Podcast appearances and mentions of Robert Strong

Did magicians discover tricks of the mind centuries before neuroscientists? Why can't you see what they're doing right in front of you? How do magicians steer your attention or appear to read your mind? Dive into the trapdoors of the human brain which allow the mind to get fooled. Join Eagleman with several guests: magician Robert Strong and cognitive neuroscientists Stephen Macknik and Susana Martinez-Conde.

Join us on 'The FreeMind Podcast' as we delve into the inspiring journey of Robert E. Strong Jr., CEO of Pretty Thai Specialty Sauces and Spices. From military service to culinary adventures, Robert shares his transition from running a popular food truck to founding a successful CPG brand. Discover the challenges and triumphs of navigating the food industry, embracing e-commerce, and building strong retail partnerships. Plus, get a heartfelt glimpse into Robert's personal life that fuels his passion for business and making a difference. Tune in for a blend of business insights and powerful storytelling!The FreeMind Podcast, sponsored by The FreeMind Group, delves into the stories of founders and senior leaders in the food and beverage industry, and beyond! Join Host, Nate Fochtman, as he interviews key figures in the food and beverage industry (and other related industries), touching upon a variety of essential topics such as their backgrounds, careers, experiences, interests and the trials and tribulations they've had to overcome. Listen as they celebrate and showcase the lives of the most influential individuals, be prepared to alter your perspective and ignite your curiosity.

Irrespective of age and culture… Magic is a wonderful world that attracts everyone. Here is why, this week's Happy Homes and Gardens has met famous magician- Robert Strong. Robert has started his magical career at the age of 12 and has been bringing joy and wonder into people's lives since then. Robert is also the Co-Author of "Amaze & Delight” Book. Here is a mesmerizing talk with her. Host: Daphne Royse

Host: Dan Holzman Holzman Studios presents the V.I.P Podcast (Very Interesting People) with special guest Magician Robert Strong.          

Irrespective of age and culture… Magic is a wonderful world that attracts everyone. Here is why, this week's Happy Homes and Gardens has met famous magician- Robert Strong. Robert has started his magical career at the age of 12 and has been bringing joy and wonder into people's lives since then. Robert is also the Co-Author of "Amaze & Delight” Book. Here is a mesmerizing talk with her. Host: Daphne Royse

The Moisture Festival releases its last interview from the Berkley sessions and we are pleased to welcome in Robert Strong. Robert is a magician, comedian, idea guy and doer of awesome things. We learn about how he found out that he is related to Harry Houdini, his encounters with Robin Williams and cold calling famous comedians … Continue reading "The Moisture Festival Podcast – Robert Strong"

Just when you thought I couldn't talk about the Strongs anymore if I tried, I found another! A surprising, previously unknown member of ancient House Strong that seemingly appeared from nowhere. And curiously about the size of the false knight, Ser Gregor Clegane. Sure there's no coincidence there.    Link to stream: https://youtu.be/vyZFMPu5sio Dying of the Light Chapter 4: https://www.patreon.com/posts/55114808 Dying of the Light chapter 2: https://www.patreon.com/posts/54241987

This week's storytellers are mystery performer Meraux Dantes, Comedy Juggler Niels Duinker, Corporate Magicians Brian Glow and Robert Strong, and Comedy Magician Shawn McMaster. This episode is entitled, "SECURITY!," and the stories all share a theme of either getting through security at the airport, dealing with law enforcement, or longing for better security in general.   Meraux Dantes: Trying to Get 4 Dozen Forks Through Security The first story is told by Meraux Dantes, a mysterious and mystical mindreader—and a charming and captivating character. Close up you’ll see him move objects without touching them and bend metal with his mind. His greatest talent is not in his fork-bending or mind-reading but in his ability to create personal connections and generate genuine warmth with every person he meets. In this story, Meraux tells about the time he tried to get four dozen forks through security at the airport. Here's where you can find out more about Meraux:  Meraux's Website   http://www.seemagiclive.com/meraux  Instagram: https://www.instagram.com/meraux_dantes/ Twitter: https://twitter.com/meraux_dantes Facebook: https://www.facebook.com/Meraux-Dantes-35018222759/ LinkedIn: https://www.linkedin.com/in/merauxdantes/   Niels Duinker: Hiding a Cut Finger Going Through Security The second story is told by Niels Duinker, a comedy juggler who has traveled the world with his act, become a multiple world record holder, and outwardly proclaims that "gravity is a joke!" In his story, Niels talks about a couple interesting experiences going through security, one in which he has to hide a cut finger.  Here's where you can find out more info about Niels: Niels' Website: http://www.comedyjuggler.com/ Amish Country Theater: http://www.amishcountrytheater.com/ Comedy Barn: http://www.comedybarn.com/ Charles Bach Theater: https://www.wonderstickets.com/   Brian Glow: Computer Under Scrutiny at Customs The third story is told by Brian Glow, a comedy magician, mentalist and illusionist in the corporate world and has been for over 40 years! In his story, Brian talks about how his brand new lap top came under very close scrutiny by some customs agents.  Here's where you can find out more about Brian: Brian's Website: http://brianglow.com/   Robert Strong: No More TSA Hassles and Living a Classig Juggler's Joke a corporate comedy magician with over 30 years experience. He's been twice voted San Francisco's Best Comedian and three times voted San Francisco's Best Magician. Whether he's producing corporate events, working the trade show floor, or strolling with close up magic, he's super easy to work with and has even been called the "nicest entertainer on the planet." In his story, Robert shares a discovery he made that makes it so TSA doesn't hassle him anymore, and then how he literally became the living embodiment of a classic juggling joke. Here's where you can find out more about Robert: Robert's Website: https://strongentertainment.com/ Robert's TEDx Talks: http://performerstories.com/robtedx   Shawn McMaster: Discovering His Cell Phone is Missing…in Mexico The final story is told by Shawn McMaster, a comedy magician who's unequaled blend of sophisticated magic and hilarious comedy has made him a highly sought-after act all over the world. His ability to blend the astonishing with the absurd has delighted countless audiences both here and abroad. Shawn tells about the time he discovered that his cellphone was missing while in Mexico. He also talks a little about his experience with the world shutting down at the beginning of the COVID outbreak. Here's where you can find out more about Shawn: Shawn's Website http://shawnmcmaster.com/   Share Your Own Stories!  Do you have comments, suggestions, or want to share your own stories? Drop me a line! performerstories@gmail.com   Exclusive Content!  Would you like exclusive content nobody else will hear? Consider supporting the shown on Patreon. You'll get the full interviews with each performer as I record them that includes all their stories all in one place with all the chat in between!   Facebook Group Come hang out in our Facebook Group! Click here to join and jump in the conversation!

This week's storytellers are Corporate magician Robert Strong, Juggler Niels Duinker, Magic Mike Brooks, and Pianist Tom Ameen. In this episode you'll hear stories that share a theme of "You Can't Make This Up!" You'll hear about an almost unfortunate coincidence at a NACA Showcase, an internationally traveling juggler getting mugged practically outside his own front door, a couple unfortunate stage faux pas involving a banana and computer software, and a fun conversation about restaurant performing and awkwardness around tips. The first storyteller is Corporate Magician Robert Strong. Based out of San Francisco, Robert is a corporate comedy magician with over 30 years experience. He's been twice voted San Francisco's Best Comedian and three times voted San Francisco's Best Magician. Whether he's producing corporate events, working the trade show floor, or strolling with close up magic, he's super easy to work with and has even been called the "nicest entertainer on the planet." In this story, Robert shares about an almost unfortunate coincidence involving him and Brian Brushwood.   The second story comes from Niels Duinker, a comedy juggler who has traveled the world with his act, become a multiple world record holder, and outwardly proclaims that "gravity is a joke!" Niels tells his story about how he, an internationally traveling entertainer, got mugged quite literally outside his own front door! The third storyteller is Magic Mike Brooks. Offering a wide variety of services from hypnosis, large-scale stage illusions, mentalism, and even close up strolling magic, Mike has become the premier choice for this kind of entertainment in and around Ohio.In his story, he talks about a couple unfortunate stage faux pas, one involving a banana and the other about how a computer pop up can screw up sound and lighting cues. Our final storyteller this episode is Tom Ameen. Tom is a Billboard Topping Pianist that's collaborated with top names in the industry like Jim Brickman and has frequently performed at many of JJ Abrams' private events. He's well-known among the Disney fan community having arranged and performed wonderful renditions of Disney classics from the theme parks and the movies. His most recent album is Stories From The Sea (Inspired by “The Outlaw Ocean” a book by Ian Urbina which is out now and can be purchased and streamed wherever you listen to your music. Here is a conversation between him and I about restaurant performing and the general awkwardness around tips. Here's where you can find out more about this week's storytellers.  Robert Strong - Corporate Magician  Robert's Website  Robert's TEDx Talks (Playlist) Niels Duinker - Juggler  Niels' Website  Comedy Barn  Amish Country Theater Magic Mike Brooks  Mike's Website Tom Ameen - Pianiat  Tom's Website Tom's New Album   Do you have comments, suggestions, or want to share your own stories? Drop me a line! performerstories@gmail.com Would you like exclusive content nobody else will hear? Consider supporting the shown Patreon. You'll get the full interviews with each performer as I record them that includes all their stories all in one place with all the chat in between! Come hang out in our new Facebook Group! Click here to join and jump in the conversation!

This week's storytellers are Carl Christman, Meraux Dantes, Shawn McMaster, Robert Strong, and Rudy Coby. In this episode you'll hear stories that share a theme of "Celebrity Encounters." A mindreader performs for a group of physicists that turns out to be the cast of a popular TV show. At a restaurant, a mentalist performs for a man who bears an uncanny resemblance to a very well-known actor. A magician performs at the Magic Castle and has surprising and hilarious encounter with a celebrity. Another magician is on the receiving end of a surprising act of gratitude from a well known actor, and finally, how one magician got conncted with and began working with one of the most well-known shock rockers in the industry. The first storyteller is Carl Christman, a magician, mentalist, teacher, and author who offers world-class mind-blowing entertainment at private and corporate events. He tells about how Three Dog Night opened for him, and then about a party he thought was for a group of physicists turned out to be for the cast of a popular sitcom.  The second story comes from Meraux Dantes, a mysterious and mystical mindreader—and a charming and captivating character based out of Orlando, FL. Close up you’ll see him move objects without touching them and bend metal with his mind. His greatest talent is not in his fork-bending or mind-reading but in his ability to create personal connections and generate genuine warmth with every person he meets. He shares a story about how he performed for a man at a restaurant who bore an uncanny resemblance to a very well known actor.  The third storyteller is Shawn McMaster, a magician who's unequaled blend of sophisticated magic and hilarious comedy has made him a highly sought-after act all over the world. His ability to blend the astonishing with the absurd has delighted countless audiences both here and abroad. In this episode he tells one story about how he met and performed for John Cleese while filling in for a friend, and another story about a surprising and humorous encounter with another celebrity that involved his act. Robert Strong is the fourth storyteller. Based out of San Francisco. Robert Strong is a corporate comedy magician with over 30 years experience. He's been twice voted San Francisco's Best Comedian and three times voted San Francisco's Best Magician. Whether he's producing corporate events, working the trade show floor, or strolling with close up magic, he's super easy to work with and has even been called the "nicest entertainer on the planet." Robert shares a story about how he was on the receiving end of a surprising act of gratitude from a well known celebrity, and another story about a famous juggler he was trying to get to take part in a festival he was producing but kept getting shot down.  The final story comes from Rudy Coby AKA Lab Man. You may have seen his ultra unique act on TV with him walking around on stage with four legs, or if you've been to a Marilyn Manson show, you've seen his work there as well, as Rudy designed all the special effects. Here he is talking about how he got connected with and started working with one of the most well-known shock rockers in the industry.  Here's where you can find out more about this week's storytellers.  Carl Christman Website Meraux Dantes Website Instagram | Facebook | Twitter Shawn McMaster Website Instagram | Facebook | Twitter Robert Strong Website TEDx Talks Rudy Coby Television Specials Facebook | Twitter Do you have comments, suggestions, or want to share your own stories? Drop me a line! performerstories@gmail.com Would you like exclusive content nobody else will hear? Consider supporting the shown Patreon. You'll get the full interviews with each performer as I record them that includes all their stories all in one place with all the chat in between! Come hang out in our Discord server! Click here for an invitation and come join the conversation!

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We are joined by special guest Joe Magician for our inaugural Halloween Livescream in which we discuss the Others and zombies, Qyburn and Robert Strong, the Nightfort, GRRM's influences and roots as a horror writer, and much more! See acast.com/privacy for privacy and opt-out information.

California Wine Country continues with its series of repeat podcast episodes featuring women in the wine business, since there is no new show due to continuing Coronavirus coverage on home station KSRO. This episode with Rebecca Robinson from ZAP was originally recorded and aired on January 10, 2018.  Rebecca Robinson is today's featured guest on California Wine Country with Steve Jaxon and Dan Berger. Rebecca is the Executive Director of ZAP, Zinfandel Advocates and Producers. ZAP will be holding ZIN EX, the Zinfandel Experience, in San Francisco, January 18-20, 2019, dedicated to Zinfandel. Robert Larsen is also back in the studio today. He spent many years at Robert Strong and now runs The Larsen Projekt. (He was last on California Wine Country in September of last year. Here is a link to the podcast of that show.) Recap of Wines Tasted Today: 2014 Acorn Zinfandel, Heritage Vines, Alegría Vineyards, Russian River Valley. 2015 Robert Biale Vineyards Zinfandel, Black Chicken, Napa Valley. 2015 Ledson Zinfandel, Sonoma Valley Reserve, Estate Ancient Vine. 2015 Armida Zinfandel, Maple Vineyards, Dry Creek Valley, Sonoma County. Today's tastings (click to enlarge). First, Steve asks Dan Berger about his wine column published today in the Press Democrat. Dan tells that it is about the large number of 2017 white wines that will start to appear in the stores over the next two months. They will be very fresh and young but they would benefit from at least another 6 months in the bottle. Read the whole article here. Dan introduces Zinfandel as a natural grape for the United States because it doesn't grow anywhere else. It was a variety that came from Europe around the turn of the previous century. It has a lot of fruit and not a lot of other places grow it. (It is grown in Italy and known by its Italian name, Primitivo.) It has a long growing season and phenomenal flavors. It can make many different styles. Rebecca Robinson's experience in Zinfandel goes back to when she was a student at Sonoma State University. She worked in the wine industry for a while before starting as Executive Director of ZAP about 20 years ago. Rebecca Robinson on ZIN EX She describes the Zinfandel Experience, which they have been producing since 1991. They are at 3 locations this year; Thursday January 18, there is a farm to table dinner at One Market. The next day there is an educational session about growing the grape and making the wine. Then on Friday night there is a winemakers' dinner and auction to support their educational foundation. On Saturday they finish with the grand tasting at Pier 27 on the Embarcadero in San Francisco. Some events are sold out, see the websites prior to the event for all updated information. Rebecca Robinson talks about how they are telling their story of how the California winemaking business has evolved and how they were successful at promoting big tasting events early on. Dan points out that Zinfandel has become one of the most interesting varietals in terms of vineyard designations. Joel Peterson at Ravenswood was a pioneer at this. You don't just look for the brands, you look for the vineyards. Some of the vines are over 100 years old and the flavors are consistent from year to year. He mentions that it can be made into everything from white wine to port, and you will see (and taste) all of those and everything in between at the event. The Flights event on Friday is about carrying Zinfandel into the future. They celebrate the living treasures of the old vineyards, but the young winemakers are in a unique position to carry it forward. Dan discusses Zinfandel as a food wine. They all had lunch today and talked about how they go with food. Lamb goes well with Zinfandel, says Steve. The 2014 Acorn Russian River Zinfandel that they are tasting is a good example. It should be decanted at least, or left in the cellar for several years.

California Wine Country continues with its series of repeat podcast episodes featuring women in the wine business, since there is no new show due to continuing Coronavirus coverage on home station KSRO. This episode with Rebecca Robinson from ZAP was originally recorded and aired on January 10, 2018.  Rebecca Robinson is today’s featured guest on California Wine Country with Steve Jaxon and Dan Berger. Rebecca is the Executive Director of ZAP, Zinfandel Advocates and Producers. ZAP will be holding ZIN EX, the Zinfandel Experience, in San Francisco, January 18-20, 2019, dedicated to Zinfandel. Robert Larsen is also back in the studio today. He spent many years at Robert Strong and now runs The Larsen Projekt. (He was last on California Wine Country in September of last year. Here is a link to the podcast of that show.) Recap of Wines Tasted Today: 2014 Acorn Zinfandel, Heritage Vines, Alegría Vineyards, Russian River Valley. 2015 Robert Biale Vineyards Zinfandel, Black Chicken, Napa Valley. 2015 Ledson Zinfandel, Sonoma Valley Reserve, Estate Ancient Vine. 2015 Armida Zinfandel, Maple Vineyards, Dry Creek Valley, Sonoma County. First, Steve asks Dan Berger about his wine column published today in the Press Democrat. Dan tells that it is about the large number of 2017 white wines that will start to appear in the stores over the next two months. They will be very fresh and young but they would benefit from at least another 6 months in the bottle. Read the whole article here. Dan introduces Zinfandel as a natural grape for the United States because it doesn't grow anywhere else. It was a variety that came from Europe around the turn of the previous century. It has a lot of fruit and not a lot of other places grow it. (It is grown in Italy and known by its Italian name, Primitivo.) It has a long growing season and phenomenal flavors. It can make many different styles. Rebecca Robinson's experience in Zinfandel goes back to when she was a student at Sonoma State University. She worked in the wine industry for a while before starting as Executive Director of ZAP about 20 years ago. Rebecca Robinson on ZIN EX She describes the Zinfandel Experience, which they have been producing since 1991. They are at 3 locations this year; Thursday January 18, there is a farm to table dinner at One Market. The next day there is an educational session about growing the grape and making the wine. Then on Friday night there is a winemakers' dinner and auction to support their educational foundation. On Saturday they finish with the grand tasting at Pier 27 on the Embarcadero in San Francisco. Some events are sold out, see the websites prior to the event for all updated information. Rebecca Robinson talks about how they are telling their story of how the California winemaking business has evolved and how they were successful at promoting big tasting events early on. Dan points out that Zinfandel has become one of the most interesting varietals in terms of vineyard designations. Joel Peterson at Ravenswood was a pioneer at this. You don't just look for the brands, you look for the vineyards. Some of the vines are over 100 years old and the flavors are consistent from year to year. He mentions that it can be made into everything from white wine to port, and you will see (and taste) all of those and everything in between at the event. The Flights event on Friday is about carrying Zinfandel into the future. They celebrate the living treasures of the old vineyards, but the young winemakers are in a unique position to carry it forward. Dan discusses Zinfandel as a food wine. They all had lunch today and talked about how they go with food. Lamb goes well with Zinfandel, says Steve. The 2014 Acorn Russian River Zinfandel that they are tasting is a good example. It should be decanted at least, or left in the cellar for several years. They thought that other dishes would be better with other Zinfandels that are not...

Today, I'm joined by Robert Strong, who is the owner of Pretty Thai specialty sauces and spices brand, and also runs the Palmer Nicklaus Foundation, which helps local area families getting fed in hospitals in trying times. Robert was a staff sergeant in the Air Force and had some unique experiences overseas. We dine on some delicious lemongrass marinated pork shoulder, pineapple ginger panini, and pork belly carnitas. The food is all fantastic, but what's even better are the stories that Robert has to share.  Having served in the military, he shares with us what kind of food troops get to eat when they're on tour, and where the military sources its ingredients from. We also talk about how easy it is to get in shape in the army, and how important diet is to our overall health. Robert is a hilarious guy, and cuts me no slack with his wit. He has me laughing so much it's hard to eat my food, but it being so tasty I just about manage…             Time Stamps: 00:42 – Where we're getting food from and what we're eating.  01:51 – Who are guest today is and what he does.  04:24 – What Robert did in the military, and his connection with Edward Snowden.  08:33 – Roberts first and second deployment, and where he was stationed.  09:59 – Working with the Navy Seals in Iraq.  14:32 – What Robert ate while on tour.  18:23 – Where the army gets its ingredients.  20:22 – What gladiators used to eat.  21:55 – How food affects both your mind and body.  23:54 – Cooking for yourself in the military.  25:11 – Getting lean, ripped and healthy.  26:47 – Our food arrives… 33:45 – Trying the pork belly carnitas.  35:39 – Doing the Camino, and how exercise allows you to drink more.  36:33 – What we think of the panini and pork shoulder.  38:00 – How much the food was.  39:53 – The Fellatio Cafe.  43:28 – Plants that emit an ‘ultrasonic scream' when they get hurt and what that means for vegans.  49:22 – The need to move towards a grain diet due to climate change.  55:30 – Our quick fire question round.  Resources:  Austin Daily Press Pretty Thai Palmer Nicklaus Foundation The Game Changers The Fellatio Cafe TexasRealFood.com Connect with Robert Strong: LinkedIn Connect with Patrick Scott Armstrong: Instagram Facebook

Robert Strong, William Lyne Wilson Professor in Political Economy at Washington and Lee University.

SPEAKERS Adam Gazzaley Professor of Neurology, UC San Francisco; Executive Director, Neuroscape Robert Strong The Comedy Magician This program was recorded in front of a live audience at the Cubberley Community Theatre in Palo Alto on July 31st, 2019.

From ancient conjurers to quick-handed con artists to Las Vegas illusionists, magicians throughout the ages have been expertly manipulating human attention and perception to dazzle and delight us. The phenomena of cognitive and sensory illusions are responsible for the “magic” of a magic trick, but how and why? Come meet neuroscientist Adam Gazzaley and magician Robert Strong as they team up to demonstrate how magicians use our brains as their accomplices in effecting the impossible—and explain what scientists can learn about the brain by studying the methods and techniques of magic. In association with Wonderfest Learn more about your ad choices. Visit megaphone.fm/adchoices

Morning service from Pastor Robert Strong. "Man Who Is Created" Genesis 1-2. Recorded 24th of February, Sunday, 2019.

Morning service from Pastor Robert Strong. Do you make time to give God praise for the things he has done in your life? Today we look at the birth of Jesus, and the praise given to God for it. "Christmas" Luke 2:1-38. Recorded 23rd of December, Sunday, 2018.

Morning Christmas praise service from Pastor Robert Strong. God has a plan for all of us, and you can not escape God's plan. How do we respond to this? This morning, we'll be looking at Mary's response to God's plan for her. Are you ready to respond to God's plan for you? "Christmas" Luke 1:26-56. Recorded 16th of December, Sunday, 2018.

Morning service from Pastor Robert Strong. Are we prepared for God's work? Are we prepared for how God will be answering our prayers? "Christmas" God will unveil his plan for John, which will lead the way for Christ, but it won't be in the way John is prepared for. Luke 1:1-25. Recorded 9th of December, Sunday, 2018.

Morning service from Pastor Robert Strong. Today's sermon looks at the second greatest event in Christian History; the return of Jesus Christ. Do you live as if he'll be coming back any second? 2 Peter 3:1-18 . Recorded 18th of November, Sunday, 2018.

Magician and professional tradeshow presenter Robert Strong sits with TradeshowGuy Tim Patterson to discuss how to draw a crowd to a booth and what to do once you have that crowd. Also, what are some good opening lines while you're standing in a tradeshow booth? Robert Strong: http://strongtradeshows.com Check out the blog at http://tradeshowguyblog.com http://tradeshowguyexhibits.com http://tradeshowexhibitbuyerskit.com http://tradeshowsuccessbook.com - get your free copy of my book! New book: http://tradeshowsuperheroes.com

Joel & Duane give a rundown of hot topics in The Wild 5, then catch up with Tim Deaver of Bob's Sporting Goods, Robert Strong of Ruckus Outfitters, & Duane gives a coho bait wrap tutorial.

John Federico (@gadgetboy) talks with David Spark (@dspark) about his new book, Three Feet from Seven Figures: One-on-One Engagement Techniques to Qualify More Leads at Trade Shows along with his experience offering comedian-led trade show training. David is joined by Robert Strong of Strong Entertainment. This episode was recorded on-location at IAEE’s 2015 Expo! Expo! Conference.

Lady Gwyn and Yolkboy analyse the monsters of A Song of Ice and Fire: Gregor Clegane, Qyburn and Ser Robert Strong, with special attention paid to Robert Strong’s role in the upcoming novels. An advert from the world of ASoIaF and specially arranged readings complete the episode. See acast.com/privacy for privacy and opt-out information.

Robert Strong, a magician of 30 years experience and ever at ease with doing what seems to be impossible, is doing something unusual even by San Francisco and his own standards. A séance. Yes, really. Skeptic though he is, he is willing to give Harry Houdini, who has been trying for 88 years, another chance to reach us. Robert...

Interview with Kalamazoo player, Robert Strong, talking about a shooting at Wayside West. We also talk to Tom Anthony, floor manager at Wayside West. Frank tries a big bluff at Firekeepers. Music by Lansing's DJ Ryno.

Dr. Bea worked with the US Army Corps of Engineers, and Royal Dutch Shell around the world. His research and teaching have focused on risk assessment and management of engineered systems. He is co-founder of Center for Catastrophic Risk Management at UCB.TranscriptSpeaker 1: Spectrum's next Speaker 2: [inaudible].Speaker 1: Welcome to spectrum the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay [00:00:30] area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hey there and good afternoon. My name is Renee Rao and I'll be hosting today's show. Today. We present part one of two interviews with Robert B. Professor emeritus of civil and environmental engineering at UC Berkeley. Dr B served as an engineer with the U S Army Corps of Engineers, Shell oil, shell development, and Royal Dutch Shell. His work has taken him to more than 60 locations around the [00:01:00] world. His engineering work has focused on marine environments. While his research and teaching have focused on risk assessment and management of engineered systems, he's a cofounder of the center for catastrophic risk management at UC Berkeley. In part one, safety and risk management are discussed. Speaker 1: Bobby, welcome to spectrum. Thank you. Pleasure. You're part of the center for catastrophic risk management. How did that get started and what's the mission? What's the goal? Well, [00:01:30] it started on an airplane coming to California from New Orleans, Louisiana. In November, 2005 on the plate with me was professor Raymond c department, Civil Environmental Engineer. In the early days after Katrina, New Orleans flooding, there were still dragging bodies out, e Eric [00:02:00] and coming, our thinking was, well, why couldn't we help found a group here at Berkeley that would bring together interdisciplinary professionals both in the academic, in Ironman and outside to address catastrophic potential failures, disasters in two frameworks, one after they happen and two before they happen, after [00:02:30] the intent is not blame, shame or hurt, but rather to learn deeply how they happen so that then you can bring it back to prevention mitigation. So we got off the plane, I met with our Dean, Dean Sastry and said, could you tell us how to become a senator here at Berkeley?Speaker 1: I'll never forget it. He got up from his test, walked around to the other side, touch me on the left and right shoulders and said, your center. [00:03:00] That telephone center happened and today the center continues to exist under the leadership of Professor Carlene Roberts and continuing to address a wide variety of accidents that have happened. And once we are working to help not happen. Thank you. Berkeley and the funding is, there is an interesting question. Initially [00:03:30] we thought, well we'll turn to the university for funding. That was not as easy as some of us thought because university was already seriously stretched for funding, just funding itself. So at that point we turned two directions. First Direction principally because of my background was to industry and said, hey and a strength, would you fund research here [00:04:00] and return for your research funding. We'll give you great students with great research backgrounds and research results. Speaker 1: They became excellent funders. We turned to government homeland security for example, or the National Science Foundation. Similar responses. So the funding has come from both industry, commerce and government. Essentially all we had to ask university four [00:04:30] and it's been a precious resource to even ask for it. It has been space and support staff. Are there any of the centers projects that you'd want to talk about? There's I think two. One was a center for catastrophic risk management project at its inception sent bro, PG and e a disaster certainly to the people that were close to land one 32 [00:05:00] that exploded. We followed that disaster from the day it started and carried it all the way through the federal investigations at state investigations and drew from that very, very important lessons, preventative lessons. The other project that has been playing out sort of in sequence with it is in San Pedro, California, the San Pedro, low pressure gas [00:05:30] storage facilities. Speaker 1: It's in a neighborhood and you can see these large gas storage tanks. You can see roads nearby. You can see Walmart in shopping centers and schools and hospitals and homes and you'd say this sounds pretty dangerous. Founded back in the 1950s period. It's pretty old, kind of like Bobby in pre oh and worn out and [00:06:00] it's severed w we call risk creep, which means when they built the tanks and the facilities there, there weren't any people, there was a port to import the gas so forth. But suddenly we've got now densely packed, I'm going to call it political social community infrastructure system, which if you blow out those tanks, we've got big trouble. Houston, well we took on San Pedro in an attempt to help the homeowners that people [00:06:30] actually live there draw or call appropriate attention to the hazard so that they could get appropriate evaluation. Speaker 1: Mid Asian, we haven't been very successful. I think many people say, well, hasn't blown up. It's not gonna blow up. Other people who say, I think I smelled gas and an explosion is not far behind. And then you turn to the state regulation system and say, [00:07:00] well, who's responsible? Answer everybody. Nobody. And at that point it sinks back into the everyday activity of that community and our society. So one horrible experience. We learned a lot of lessons and I'm watching PG and e n r California Public Utilities Commission go through the learning experiences and they're obviously painful. But on the preventative side, art record is looking [00:07:30] pretty dismal. Yeah, that's tough. That's similar to the Chevron fire that was in Richmond and cause you're right, these things get built when they're far away and then developers build right up to them. Same with airports and all sorts of faculty. Speaker 1: Chevron refinery is what our latest investigation and it's got a story behind it because one of the stalwart sponsors at work that's been done by the center for catastrophic [00:08:00] risk management has been Chevron. In fact, they were a member of um, 10 years study that we conducted here concerning how organizations manage very high risk systems successfully. Chevron was one of the successful organizations. So when we saw Richmond go poof, boon, we said something's changed. [00:08:30] They had a sterling record for their operations here. What happened? Well, the story comes that this business of risk assessment management of these complex systems is one damn thing after another. And if you get your attention diverted like, oh, we need to make more money, you start diverting precious human resources working to achieve, say that he them [00:09:00] safety starts to degrade and at that point roasty Pintful only stay rusty so long at that point, poof, boom. Speaker 3: You're listening to spectrum on k a Alex Berkeley. Brad swift is interviewing Bob, be a civil and environmental engineer at UC Berkeley. In the next segment they talk about collaboration. Speaker 4: [00:09:30] Talk about some of the people you've collaborated with and the benefits that flow from Speaker 1: that kind of work. That's been one of the real blessings of my life has been collaboration. One of the things that dealing with complex problems and systems and most afraid of is myself. I'm afraid of myself because I know I'll think about something [00:10:00] in a single boy and I'll think about it from the knowledge I have and then all develop a solution or insight to how something happens. Given that set of intellectual tools and so learned to be afraid of myself and I get very comfortable is when I have people who don't think like me, who will in fact listen to me and then respectfully when I finished they say, [00:10:30] Oh, you're wrong. Here's why. And then of course out rock back and I say, okay, he explains more or less, let's get there. And what I have found in evitable Lee is I end up at a different point than where I started, which tells me the power of collaboration can be extremely strong as long as collaboration is knowledgeable and respectful. If it gets to be ignorance at work and it's disrespectful, you can expect Bob [00:11:00] to become pretty nasty. [inaudible]. Speaker 4: In reflection on your activities in civil engineering and in academia, does civil engineering need to change in some way or is there a subtle change happening that you recognize? Speaker 1: I think there's subtle change having and proud. I think I see it starting to sprout here at Berkeley. The change that's happening is that you struck on with your earlier question concerning collaboration. [00:11:30] So it turns out to be the power of civil engineering collaboration. We've actually got people in engineering working with people in political science, public health business. That is an extremely encouraging sign. As long as we can keep that collaboration going in the right directions. If you do that, do it well. Then this symphony of disasters and accidents, we'll hear that [00:12:00] music go down a lot. You sort of made famous, the civil engineering course one 80 and you're not teaching that anymore, right? That's correct. Did you pass it on to someone you know and give them the blessing? I tried to, yeah. C e one e engineering systems is what it was called, I think was teachable for me because of the experiences. Speaker 1: [00:12:30] I came here after 35 years, 36 years of industry work, and I've been working as laborers since I was 14 went to work as a roofer roofing crew in Florida. I'm not too smart, and so I was able to bring that background experience into the classroom and virtually turned the students loose, said we don't want you to do is first formed into teams. Well a year [00:13:00] at Berkeley, we tend to be what I call a star system student is independent. They gotta be the best in the class working together as something not encouraged. Well, I would say to hell with the star system, we're going to work as a team. So teamwork came in and that's because that hit very strong training through the Harvard Executive Master of Business Administration Program on teamwork and organization and that kind of stuff. So I brought that in and then said, well you have all this [00:13:30] technical stuff. Speaker 1: Get out of Berkeley, go out there and meet the real people, meet some real experts outside of the Berkeley experts and go solve problems. So essentially I turned them loose, but I kept him from hurting themselves. It worked beautifully. Well notice you can't then turn back to normal Berkeley faculty and say, teach it. It's not reasonable because he's not had that [00:14:00] experience. You could think about team teaching, but then you'd say, well ob, we have trouble with enough funding to teach with one person in a class, much less teen teaching. So I sort of agreed with myself to hope somebody remembers and when the university has more resources they could in fact return to these times of real life experience classes. The students that came [00:14:30] through that sort of experiences have made some remarkable contributions already. Good kids. Has anyone approached you about doing any of this online teaching? Speaker 1: Yes, and I steadily said no. The reason is a saying that I was given by a very dear friend and a collaborator, University of Washington, Seattle said a bomb. [00:15:00] Engineers want to believe the planet is not inhabited. We don't like people were antisocial. Go to a party and you can tell it immediately you were in a corner, you know, talking boring shop. Well let, don't want to contribute to e offline internet generation of engineers who do let her work with each other. I have all the liberating intellectual things in the classroom outside of the classroom. So [00:15:30] [inaudible] been very supportive. We need more human contact. Speaker 2: [inaudible]Speaker 5: spectrum is a public affairs show on KALX Berkeley. Our guest is professor Bob B of UC Berkeley. In the next segment they speak about safety. Speaker 2: Aw. Speaker 1: Is there anything that I haven't asked you about that you want to talk about? One of the things [00:16:00] that as I leave my career period in my career at Berkeley that makes me sad for Berkeley really got my attention during the Macondo disaster. Many good friends that I still have at DPE that were in fact involved in the causation of the accident kept saying, well, what we did we thought was safe. The thing that makes me say [00:16:30] is we still have a course to teach engineers what the word means and how to quantify it so that then people can look at it and say, this is acceptable. Those people could be from the school football or public hill. This kind of risk management not happening here. That's I had, and I can look forward. I think all of us can two continuing problems in this area because of a lack of appropriate [00:17:00] education. The engineering thinking in many cases is w explicit thinking about uncertainties, variability and is devoid of thinking intensely about the potential effects. Uh, human malfunctions. The engineer goes through a career of saying the weld will be done according to specifications. There's where it pumps up. [00:17:30] The engineers. Education is one a deals with an imaginary world. There is no significant uncertainty. You sorta by code specification or however inspection do away with that and things will be perfectly [inaudible]. Guess what? It's not the human factor, the human factor. Speaker 4: Given that there's always going to be that human factor [00:18:00] at risk management seems to be a quandary of the open-endedness of it. When do you feel you've done enough of it? When do you feel confident that you're ready to say, yes, I'm prepared for all circumstances? No one can know all things yet at the same time, you do as much as you can or what can you afford? Right. It comes down to the money side of it again. Yeah. I Speaker 1: love your question. I got on this while I was here, so I didn't come in here knowing this [00:18:30] one, when I came in to this risk assessment, management got into the depths of it. I had to do a lot of reading and reading. I was doing coming from many different industries and parts of the world said, oh well risk assessment and even a proactive think before predict cause like you were saying. But the falling that is, you can't predict everything, but they never said it. Okay. And the next thing you said was it's reactive [00:19:00] so that when something bad happens, you reflect on it, learn from it, and you manage the consequences. Well, I'm sitting here and by the way, I came here without a phd, but I got one, all of them white. I introduced interactive management and I'm sitting at home trying to think how to do something for a PhD dissertation that's new. Speaker 1: And I said, oh, there's proactive and there's reactive that gotta be interactive. How in the hell can I learn about this? And I end up working [00:19:30] with two pediatric emergency room management teams, a BB team, I call them [inaudible] into hospital Los Angeles, the other San Francisco general mortality rate, same number of beds in air emergency room wards was a factor of 10 higher in San Francisco. So we went and observed them, students with me, and we started interactive management. The baby can't tell you what's wrong with it [00:20:00] and yet the medical team has to be able to diagnose it, invoke corrective action to save the life and the success shows up in mortality. So we got deep into that and that entered interacted management. Hey, story goes on. We're working with commercial aviation, U S air, United Airlines and southwest airlines. U Us air comes to a confidential meeting and says, [00:20:30] well, we found out where we had five fatal accidents five years in a row. Speaker 1: We had given our flight crews instructions. They were to leave the gate on time without exception. Well, the five that had crashes did the checkout on the taxi out. Two of them found that they didn't have enough fuel to make the next airport unless they have tail. Winston. Of course they had headwinds. Well then experience in his interactive [00:21:00] management. The guy shows up at our doorstep here in Maine, sully Sullenberger and he's learning about what we have been learning. He's heard through u s air about this interactive management. Boy Did we carry him through it and boy did. He carry us through perfect example of how you can prepare a very complex hazardous system to succeed [00:21:30] in the face of failure. What they did that morning and he sent me an email that morning before they took off from the Guardian when they took all laws, both engines totally not predictable, did the scan or the alternative airports and what would happen if they didn't have enough flight path to make it turn toward the Hudson and pulled off. That was totally prepared for including design of back water back flow valves through the air intakes into [00:22:00] the Airbus. He knew what he was doing. Look at the flight inclination of the plane coming into the river. Looks like barefoot skiers toes up. Speaker 1: There's the power of the thinking so you do end up measuring safety just to, you said you never sure you got the spit on it or right. Something could happen out of the blue. Somebody walks across the street that's not supposed to. You then have to have the ability to get through [00:22:30] the system quickly and have the correct response. That's part of risk assessment management. Unfortunately, BP never learned it before the conduct so that when it really hit hard, it hit hard. That night they couldn't respond. They froze and they killed 11 people at White. Yeah, I read the report that you did on that and I was like potboiler. [00:23:00] It's really riveting stuff. Yup. Speaker 1: That's an amazing tale. Yeah, it makes me so overwhelming. Go sailing. You say all in the bay, Yo God, you know? Yeah. I'd taken the boat to Mexico taking the channel islands twice. I'm single handed sailor. Oh really? I've lost my ass once. Those exciting tale about [00:23:30] disaster preparation, I guess sailing alone is a good sort of a risk management hands on practice reason. You'd say, come on Bob, you got it. He's somewhat here, man. I've learned. When I say go, I can only sale, which means I can't think about Katrina or beat pea or San Bruno. I've got to focus totally on that boat and sailing. If not, I ask here quick. So it's a relief and that's why you do the [00:24:00] solo rather than have other people on board. Then you get sloppy, sloppy, and et cetera. Yeah, and so most of my sailing is done solo. Speaker 6: No [inaudible]. Speaker 3: If you're interested in the center for catastrophic risk management and it's riveting reports, visit the website, c c r n. Dot berkeley.edu [00:24:30] to listen to any and every past episode of spectrum for free. Visit our archive on iTunes university. The link is tiny url.com/calyx spectrum. Now two of the science and technology events happening locally over the next two weeks. Cheese, Yucca boss and I presented a calendar Speaker 7: this Tuesday, November 19th the SF ask a scientist's lecture series. [00:25:00] We'll present a talk by a neuroscientist, Adam Gazzaley and magician Robert Strong from ancient conjures to big ticket Las Vegas. Illusionists. Magicians have been expertly manipulating human attention and perception to dazzle and delight us. The team will demonstrate how magicians use our brains as their accomplices in effecting the impossible and explain what scientists can learn about the brain by studying the methods and techniques of magic. The event will take place on Tuesday, November 19th at 7:00 PM in Stanford's geology corner. Auditorium Room [00:25:30] Number One oh five and building number three 20 of Stanford's main quad. Speaker 3: This Wednesday, November 20th the UC Berkeley Archeological Research Facility will host a seminar on indigenous food ways and landscape management. Since 2007 a multidisciplinary research team has been working to implement an Eto archeological approach to explore indigenous landscape management on the central coast of California. This presentation includes results of a study associated with UC Berkeley Graduate Student Rob Casseroles, [00:26:00] dissertation research, which takes a historical ecological approach to integrating major sources of data, including fiery ecology of contemporary landscapes and results of macro botanical analysis of indigenous settlements. The event is open to all audiences and will be held on November 20th from 12 to 1:00 PM in room one oh one of the archaeological research facility on the UC Berkeley campus and now Chase Jakubowski with our new story. Speaker 7: This story is from the UC Berkeley new center. [00:26:30] CRISPR stands for clustered regularly interspaced short palindromic repeats for nearly two decades after Japanese researchers first discovered CRISPR in bacteria in 1987 scientists dismissed it as junk DNA, far from being junk. CRISPR was actually a way of storing the genetic information of an invading virus in the form of Palindromic DNA sequence. The bacteria used this genetic information to target the viral invader by chopping [00:27:00] it up with powerful CRISPR associated enzymes capable of cleaving its DNA molecule, just like a pair of molecular scissors. The mystery of CRISPR was resolved by Jennifer Doudna of the University of California Berkeley, a specialist in RNA about seven years ago. Downer was asked by a university colleague to look into this genetic particularity of bacteria and quickly became fascinated. The more we looked into it, the more it seemed extremely interesting. Professor Doudna [00:27:30] said then in 2011 she met Emmanuelle Carpentier of Ooma University in Sweden at a scientific conference. Speaker 7: Professor Carpentier told professor down a of another kind of CRISPR system that seemed to rely on a single gene called c a s nine both professors collaborated on the project and an August last year published what is now considered the seminal paper showing that cas nine was an enzyme capable of cutting both [00:28:00] strands of DNA double helix at precisely the point dictated by a programmable RNA sequence. In other words, an RNA molecule that could be made to order. It has worked beautifully on plants and animals. Professors Doudna and sharpen ta had found the holy grail of genetic engineering, a method of cutting and stitching DNA accurately and simply anywhere in a complex genome. I'm tremendously excited about the possibility of this discovery having a real impact on people's [00:28:30] lives. Maybe we'll offer the opportunity to do therapeutics that we've not been able to do in the past. Professor Doudna said her team is already working on possible ways of using the cas nine system to disrupt the damaging chromosomes responsible for down syndrome or the extra repetitive sequences of DNA that lead to Huntington's disease. What's exciting is that you can see the potential and it's certainly going to drive a lot of research to try to explore it as a potential human therapeutic tool. Speaker 3: [00:29:00] Mm. Don't forget to tune in next week to your part two professor B's interview. He and Brad Swift will discuss the California Delta and shoreline retreat. Okay. The music heard during this show was written and produced by Alex Simon. Thank you for listening to spectrum. If you have comments about the show, please send them to us via email. [00:29:30] Our email address is spectrum KALX. Hey, yahoo.com join us in two weeks. [inaudible]. See acast.com/privacy for privacy and opt-out information.

Dr. Bea worked with the US Army Corps of Engineers, and Royal Dutch Shell around the world. His research and teaching have focused on risk assessment and management of engineered systems. He is co-founder of Center for Catastrophic Risk Management at UCB.TranscriptSpeaker 1: Spectrum's next Speaker 2: [inaudible].Speaker 1: Welcome to spectrum the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay [00:00:30] area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hey there and good afternoon. My name is Renee Rao and I'll be hosting today's show. Today. We present part one of two interviews with Robert B. Professor emeritus of civil and environmental engineering at UC Berkeley. Dr B served as an engineer with the U S Army Corps of Engineers, Shell oil, shell development, and Royal Dutch Shell. His work has taken him to more than 60 locations around the [00:01:00] world. His engineering work has focused on marine environments. While his research and teaching have focused on risk assessment and management of engineered systems, he's a cofounder of the center for catastrophic risk management at UC Berkeley. In part one, safety and risk management are discussed. Speaker 1: Bobby, welcome to spectrum. Thank you. Pleasure. You're part of the center for catastrophic risk management. How did that get started and what's the mission? What's the goal? Well, [00:01:30] it started on an airplane coming to California from New Orleans, Louisiana. In November, 2005 on the plate with me was professor Raymond c department, Civil Environmental Engineer. In the early days after Katrina, New Orleans flooding, there were still dragging bodies out, e Eric [00:02:00] and coming, our thinking was, well, why couldn't we help found a group here at Berkeley that would bring together interdisciplinary professionals both in the academic, in Ironman and outside to address catastrophic potential failures, disasters in two frameworks, one after they happen and two before they happen, after [00:02:30] the intent is not blame, shame or hurt, but rather to learn deeply how they happen so that then you can bring it back to prevention mitigation. So we got off the plane, I met with our Dean, Dean Sastry and said, could you tell us how to become a senator here at Berkeley?Speaker 1: I'll never forget it. He got up from his test, walked around to the other side, touch me on the left and right shoulders and said, your center. [00:03:00] That telephone center happened and today the center continues to exist under the leadership of Professor Carlene Roberts and continuing to address a wide variety of accidents that have happened. And once we are working to help not happen. Thank you. Berkeley and the funding is, there is an interesting question. Initially [00:03:30] we thought, well we'll turn to the university for funding. That was not as easy as some of us thought because university was already seriously stretched for funding, just funding itself. So at that point we turned two directions. First Direction principally because of my background was to industry and said, hey and a strength, would you fund research here [00:04:00] and return for your research funding. We'll give you great students with great research backgrounds and research results. Speaker 1: They became excellent funders. We turned to government homeland security for example, or the National Science Foundation. Similar responses. So the funding has come from both industry, commerce and government. Essentially all we had to ask university four [00:04:30] and it's been a precious resource to even ask for it. It has been space and support staff. Are there any of the centers projects that you'd want to talk about? There's I think two. One was a center for catastrophic risk management project at its inception sent bro, PG and e a disaster certainly to the people that were close to land one 32 [00:05:00] that exploded. We followed that disaster from the day it started and carried it all the way through the federal investigations at state investigations and drew from that very, very important lessons, preventative lessons. The other project that has been playing out sort of in sequence with it is in San Pedro, California, the San Pedro, low pressure gas [00:05:30] storage facilities. Speaker 1: It's in a neighborhood and you can see these large gas storage tanks. You can see roads nearby. You can see Walmart in shopping centers and schools and hospitals and homes and you'd say this sounds pretty dangerous. Founded back in the 1950s period. It's pretty old, kind of like Bobby in pre oh and worn out and [00:06:00] it's severed w we call risk creep, which means when they built the tanks and the facilities there, there weren't any people, there was a port to import the gas so forth. But suddenly we've got now densely packed, I'm going to call it political social community infrastructure system, which if you blow out those tanks, we've got big trouble. Houston, well we took on San Pedro in an attempt to help the homeowners that people [00:06:30] actually live there draw or call appropriate attention to the hazard so that they could get appropriate evaluation. Speaker 1: Mid Asian, we haven't been very successful. I think many people say, well, hasn't blown up. It's not gonna blow up. Other people who say, I think I smelled gas and an explosion is not far behind. And then you turn to the state regulation system and say, [00:07:00] well, who's responsible? Answer everybody. Nobody. And at that point it sinks back into the everyday activity of that community and our society. So one horrible experience. We learned a lot of lessons and I'm watching PG and e n r California Public Utilities Commission go through the learning experiences and they're obviously painful. But on the preventative side, art record is looking [00:07:30] pretty dismal. Yeah, that's tough. That's similar to the Chevron fire that was in Richmond and cause you're right, these things get built when they're far away and then developers build right up to them. Same with airports and all sorts of faculty. Speaker 1: Chevron refinery is what our latest investigation and it's got a story behind it because one of the stalwart sponsors at work that's been done by the center for catastrophic [00:08:00] risk management has been Chevron. In fact, they were a member of um, 10 years study that we conducted here concerning how organizations manage very high risk systems successfully. Chevron was one of the successful organizations. So when we saw Richmond go poof, boon, we said something's changed. [00:08:30] They had a sterling record for their operations here. What happened? Well, the story comes that this business of risk assessment management of these complex systems is one damn thing after another. And if you get your attention diverted like, oh, we need to make more money, you start diverting precious human resources working to achieve, say that he them [00:09:00] safety starts to degrade and at that point roasty Pintful only stay rusty so long at that point, poof, boom. Speaker 3: You're listening to spectrum on k a Alex Berkeley. Brad swift is interviewing Bob, be a civil and environmental engineer at UC Berkeley. In the next segment they talk about collaboration. Speaker 4: [00:09:30] Talk about some of the people you've collaborated with and the benefits that flow from Speaker 1: that kind of work. That's been one of the real blessings of my life has been collaboration. One of the things that dealing with complex problems and systems and most afraid of is myself. I'm afraid of myself because I know I'll think about something [00:10:00] in a single boy and I'll think about it from the knowledge I have and then all develop a solution or insight to how something happens. Given that set of intellectual tools and so learned to be afraid of myself and I get very comfortable is when I have people who don't think like me, who will in fact listen to me and then respectfully when I finished they say, [00:10:30] Oh, you're wrong. Here's why. And then of course out rock back and I say, okay, he explains more or less, let's get there. And what I have found in evitable Lee is I end up at a different point than where I started, which tells me the power of collaboration can be extremely strong as long as collaboration is knowledgeable and respectful. If it gets to be ignorance at work and it's disrespectful, you can expect Bob [00:11:00] to become pretty nasty. [inaudible]. Speaker 4: In reflection on your activities in civil engineering and in academia, does civil engineering need to change in some way or is there a subtle change happening that you recognize? Speaker 1: I think there's subtle change having and proud. I think I see it starting to sprout here at Berkeley. The change that's happening is that you struck on with your earlier question concerning collaboration. [00:11:30] So it turns out to be the power of civil engineering collaboration. We've actually got people in engineering working with people in political science, public health business. That is an extremely encouraging sign. As long as we can keep that collaboration going in the right directions. If you do that, do it well. Then this symphony of disasters and accidents, we'll hear that [00:12:00] music go down a lot. You sort of made famous, the civil engineering course one 80 and you're not teaching that anymore, right? That's correct. Did you pass it on to someone you know and give them the blessing? I tried to, yeah. C e one e engineering systems is what it was called, I think was teachable for me because of the experiences. Speaker 1: [00:12:30] I came here after 35 years, 36 years of industry work, and I've been working as laborers since I was 14 went to work as a roofer roofing crew in Florida. I'm not too smart, and so I was able to bring that background experience into the classroom and virtually turned the students loose, said we don't want you to do is first formed into teams. Well a year [00:13:00] at Berkeley, we tend to be what I call a star system student is independent. They gotta be the best in the class working together as something not encouraged. Well, I would say to hell with the star system, we're going to work as a team. So teamwork came in and that's because that hit very strong training through the Harvard Executive Master of Business Administration Program on teamwork and organization and that kind of stuff. So I brought that in and then said, well you have all this [00:13:30] technical stuff. Speaker 1: Get out of Berkeley, go out there and meet the real people, meet some real experts outside of the Berkeley experts and go solve problems. So essentially I turned them loose, but I kept him from hurting themselves. It worked beautifully. Well notice you can't then turn back to normal Berkeley faculty and say, teach it. It's not reasonable because he's not had that [00:14:00] experience. You could think about team teaching, but then you'd say, well ob, we have trouble with enough funding to teach with one person in a class, much less teen teaching. So I sort of agreed with myself to hope somebody remembers and when the university has more resources they could in fact return to these times of real life experience classes. The students that came [00:14:30] through that sort of experiences have made some remarkable contributions already. Good kids. Has anyone approached you about doing any of this online teaching? Speaker 1: Yes, and I steadily said no. The reason is a saying that I was given by a very dear friend and a collaborator, University of Washington, Seattle said a bomb. [00:15:00] Engineers want to believe the planet is not inhabited. We don't like people were antisocial. Go to a party and you can tell it immediately you were in a corner, you know, talking boring shop. Well let, don't want to contribute to e offline internet generation of engineers who do let her work with each other. I have all the liberating intellectual things in the classroom outside of the classroom. So [00:15:30] [inaudible] been very supportive. We need more human contact. Speaker 2: [inaudible]Speaker 5: spectrum is a public affairs show on KALX Berkeley. Our guest is professor Bob B of UC Berkeley. In the next segment they speak about safety. Speaker 2: Aw. Speaker 1: Is there anything that I haven't asked you about that you want to talk about? One of the things [00:16:00] that as I leave my career period in my career at Berkeley that makes me sad for Berkeley really got my attention during the Macondo disaster. Many good friends that I still have at DPE that were in fact involved in the causation of the accident kept saying, well, what we did we thought was safe. The thing that makes me say [00:16:30] is we still have a course to teach engineers what the word means and how to quantify it so that then people can look at it and say, this is acceptable. Those people could be from the school football or public hill. This kind of risk management not happening here. That's I had, and I can look forward. I think all of us can two continuing problems in this area because of a lack of appropriate [00:17:00] education. The engineering thinking in many cases is w explicit thinking about uncertainties, variability and is devoid of thinking intensely about the potential effects. Uh, human malfunctions. The engineer goes through a career of saying the weld will be done according to specifications. There's where it pumps up. [00:17:30] The engineers. Education is one a deals with an imaginary world. There is no significant uncertainty. You sorta by code specification or however inspection do away with that and things will be perfectly [inaudible]. Guess what? It's not the human factor, the human factor. Speaker 4: Given that there's always going to be that human factor [00:18:00] at risk management seems to be a quandary of the open-endedness of it. When do you feel you've done enough of it? When do you feel confident that you're ready to say, yes, I'm prepared for all circumstances? No one can know all things yet at the same time, you do as much as you can or what can you afford? Right. It comes down to the money side of it again. Yeah. I Speaker 1: love your question. I got on this while I was here, so I didn't come in here knowing this [00:18:30] one, when I came in to this risk assessment, management got into the depths of it. I had to do a lot of reading and reading. I was doing coming from many different industries and parts of the world said, oh well risk assessment and even a proactive think before predict cause like you were saying. But the falling that is, you can't predict everything, but they never said it. Okay. And the next thing you said was it's reactive [00:19:00] so that when something bad happens, you reflect on it, learn from it, and you manage the consequences. Well, I'm sitting here and by the way, I came here without a phd, but I got one, all of them white. I introduced interactive management and I'm sitting at home trying to think how to do something for a PhD dissertation that's new. Speaker 1: And I said, oh, there's proactive and there's reactive that gotta be interactive. How in the hell can I learn about this? And I end up working [00:19:30] with two pediatric emergency room management teams, a BB team, I call them [inaudible] into hospital Los Angeles, the other San Francisco general mortality rate, same number of beds in air emergency room wards was a factor of 10 higher in San Francisco. So we went and observed them, students with me, and we started interactive management. The baby can't tell you what's wrong with it [00:20:00] and yet the medical team has to be able to diagnose it, invoke corrective action to save the life and the success shows up in mortality. So we got deep into that and that entered interacted management. Hey, story goes on. We're working with commercial aviation, U S air, United Airlines and southwest airlines. U Us air comes to a confidential meeting and says, [00:20:30] well, we found out where we had five fatal accidents five years in a row. Speaker 1: We had given our flight crews instructions. They were to leave the gate on time without exception. Well, the five that had crashes did the checkout on the taxi out. Two of them found that they didn't have enough fuel to make the next airport unless they have tail. Winston. Of course they had headwinds. Well then experience in his interactive [00:21:00] management. The guy shows up at our doorstep here in Maine, sully Sullenberger and he's learning about what we have been learning. He's heard through u s air about this interactive management. Boy Did we carry him through it and boy did. He carry us through perfect example of how you can prepare a very complex hazardous system to succeed [00:21:30] in the face of failure. What they did that morning and he sent me an email that morning before they took off from the Guardian when they took all laws, both engines totally not predictable, did the scan or the alternative airports and what would happen if they didn't have enough flight path to make it turn toward the Hudson and pulled off. That was totally prepared for including design of back water back flow valves through the air intakes into [00:22:00] the Airbus. He knew what he was doing. Look at the flight inclination of the plane coming into the river. Looks like barefoot skiers toes up. Speaker 1: There's the power of the thinking so you do end up measuring safety just to, you said you never sure you got the spit on it or right. Something could happen out of the blue. Somebody walks across the street that's not supposed to. You then have to have the ability to get through [00:22:30] the system quickly and have the correct response. That's part of risk assessment management. Unfortunately, BP never learned it before the conduct so that when it really hit hard, it hit hard. That night they couldn't respond. They froze and they killed 11 people at White. Yeah, I read the report that you did on that and I was like potboiler. [00:23:00] It's really riveting stuff. Yup. Speaker 1: That's an amazing tale. Yeah, it makes me so overwhelming. Go sailing. You say all in the bay, Yo God, you know? Yeah. I'd taken the boat to Mexico taking the channel islands twice. I'm single handed sailor. Oh really? I've lost my ass once. Those exciting tale about [00:23:30] disaster preparation, I guess sailing alone is a good sort of a risk management hands on practice reason. You'd say, come on Bob, you got it. He's somewhat here, man. I've learned. When I say go, I can only sale, which means I can't think about Katrina or beat pea or San Bruno. I've got to focus totally on that boat and sailing. If not, I ask here quick. So it's a relief and that's why you do the [00:24:00] solo rather than have other people on board. Then you get sloppy, sloppy, and et cetera. Yeah, and so most of my sailing is done solo. Speaker 6: No [inaudible]. Speaker 3: If you're interested in the center for catastrophic risk management and it's riveting reports, visit the website, c c r n. Dot berkeley.edu [00:24:30] to listen to any and every past episode of spectrum for free. Visit our archive on iTunes university. The link is tiny url.com/calyx spectrum. Now two of the science and technology events happening locally over the next two weeks. Cheese, Yucca boss and I presented a calendar Speaker 7: this Tuesday, November 19th the SF ask a scientist's lecture series. [00:25:00] We'll present a talk by a neuroscientist, Adam Gazzaley and magician Robert Strong from ancient conjures to big ticket Las Vegas. Illusionists. Magicians have been expertly manipulating human attention and perception to dazzle and delight us. The team will demonstrate how magicians use our brains as their accomplices in effecting the impossible and explain what scientists can learn about the brain by studying the methods and techniques of magic. The event will take place on Tuesday, November 19th at 7:00 PM in Stanford's geology corner. Auditorium Room [00:25:30] Number One oh five and building number three 20 of Stanford's main quad. Speaker 3: This Wednesday, November 20th the UC Berkeley Archeological Research Facility will host a seminar on indigenous food ways and landscape management. Since 2007 a multidisciplinary research team has been working to implement an Eto archeological approach to explore indigenous landscape management on the central coast of California. This presentation includes results of a study associated with UC Berkeley Graduate Student Rob Casseroles, [00:26:00] dissertation research, which takes a historical ecological approach to integrating major sources of data, including fiery ecology of contemporary landscapes and results of macro botanical analysis of indigenous settlements. The event is open to all audiences and will be held on November 20th from 12 to 1:00 PM in room one oh one of the archaeological research facility on the UC Berkeley campus and now Chase Jakubowski with our new story. Speaker 7: This story is from the UC Berkeley new center. [00:26:30] CRISPR stands for clustered regularly interspaced short palindromic repeats for nearly two decades after Japanese researchers first discovered CRISPR in bacteria in 1987 scientists dismissed it as junk DNA, far from being junk. CRISPR was actually a way of storing the genetic information of an invading virus in the form of Palindromic DNA sequence. The bacteria used this genetic information to target the viral invader by chopping [00:27:00] it up with powerful CRISPR associated enzymes capable of cleaving its DNA molecule, just like a pair of molecular scissors. The mystery of CRISPR was resolved by Jennifer Doudna of the University of California Berkeley, a specialist in RNA about seven years ago. Downer was asked by a university colleague to look into this genetic particularity of bacteria and quickly became fascinated. The more we looked into it, the more it seemed extremely interesting. Professor Doudna [00:27:30] said then in 2011 she met Emmanuelle Carpentier of Ooma University in Sweden at a scientific conference. Speaker 7: Professor Carpentier told professor down a of another kind of CRISPR system that seemed to rely on a single gene called c a s nine both professors collaborated on the project and an August last year published what is now considered the seminal paper showing that cas nine was an enzyme capable of cutting both [00:28:00] strands of DNA double helix at precisely the point dictated by a programmable RNA sequence. In other words, an RNA molecule that could be made to order. It has worked beautifully on plants and animals. Professors Doudna and sharpen ta had found the holy grail of genetic engineering, a method of cutting and stitching DNA accurately and simply anywhere in a complex genome. I'm tremendously excited about the possibility of this discovery having a real impact on people's [00:28:30] lives. Maybe we'll offer the opportunity to do therapeutics that we've not been able to do in the past. Professor Doudna said her team is already working on possible ways of using the cas nine system to disrupt the damaging chromosomes responsible for down syndrome or the extra repetitive sequences of DNA that lead to Huntington's disease. What's exciting is that you can see the potential and it's certainly going to drive a lot of research to try to explore it as a potential human therapeutic tool. Speaker 3: [00:29:00] Mm. Don't forget to tune in next week to your part two professor B's interview. He and Brad Swift will discuss the California Delta and shoreline retreat. Okay. The music heard during this show was written and produced by Alex Simon. Thank you for listening to spectrum. If you have comments about the show, please send them to us via email. [00:29:30] Our email address is spectrum KALX. Hey, yahoo.com join us in two weeks. [inaudible]. Hosted on Acast. See acast.com/privacy for more information.

Zoologist Toni Bodi is currently developing a genomic diagnostic screen for Alzheimer’s disease and is a founding member of the Berkeley Bio Labs new bio hacker space. Nature magazine.TranscriptSpeaker 1: Spectrum's next. Speaker 2: Aw. [inaudible] [inaudible] [inaudible] [inaudible] [inaudible]. Speaker 1: Welcome to spectrum the science [00:00:30] and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hi and good afternoon. My name is Brad Swift. I'm the host of today's show. Our guest is Tony Bodhi Hickerson, a zoologist who was part of a cognitive study of howler monkeys in Mexico. Tony is trying to organize a noninvasive [00:01:00] dolphin study in the wild using wireless network technology. She is currently developing a genomic diagnostic screen for Alzheimer's disease and is a founding member of the Berkeley bio labs, a new bio hackerspace. Tony talks about cognition, Alzheimer's disease, and creating a scientific community resource in the bay area. Rick Karnofsky and Renee Rau interview Tony on this edition of spectrum. Speaker 4: So welcome to spectrum. [00:01:30] I'm Rick Karnofsky here with Brad swift and Renee Rao. Our guest today on spectrum is Tony Bodhi, Hickerson and zoologist. Welcome to spectrum. Thank you for having me. Can you give us a little bit of a description of what you work on? Kind of a brief overview for the audience. That cognition is essentially the ability to receive and process information and the most abstract form. And we kind of think of it as mental processes, which can be both conscious and subconscious. [00:02:00] And so I do research on cognitive abilities of wildlife and at the moment I'm also working on an application in humans. What wildlife do you look at? Um, well I have looked at primates and I've been also involved in a dolphin project. So high functioning mammals. And how do you assess their cognitive abilities? Well, you can do behavioral studies, which is what I primarily do. Speaker 4: And of course just looking at the anatomy as well. So [00:02:30] I try to be as noninvasive as possible. I don't work in a lab with monkeys in a cage. I actually work in the wilderness and follow monkeys around all day. So where do you do that? I was doing that in Mexico for my last study with seven months and from Sunup I watched the sun come up and uh, the howler monkeys, which is a species that I was working on would call in the morning. That's how we'd find them. So we trek through the jungle and find them and then start our study. And it would usually last, well it would last until sundown. So depending on how many hours a like we had [00:03:00] [inaudible] Speaker 5: can you just walk us through what the study was and what you looked at in the howler monkeys and how you interpreted it? Speaker 4: Well, this study, I was a, the head field managers, so it wasn't my particular study, but I was managing all the data collection and uh, we were looking at two different species of Holler monkey. And they're hybrids. So there's hybrid zone in Mexico where both of these species, which we believe based on genetic evidence have been separated for about 3 million [00:03:30] years. They have different number of sex chromosomes. They're very morphologically different, are coming together and meeting successfully. They also have very different social structures and one group tends to be far more aggressive than the other one is much more communal. It has large groups up to 25 30 and the other one usually has three to five. So to see how behaviorly they come together and genetically they come together because in one cross if you have a female of a and a male of B, they can [00:04:00] have an offspring. But if you inverse it they cannot. So it's really interesting also genetically to see how things recombine. What kinds of data did you take? Oh, we took auditory, so we, they're hollow monkeys. So we had all their calls, which it changes from group to group and obviously from species to species. We also took a lot of behavioral information, affiliative, so like affection and aggressive behavior, like attacks and genetic [00:04:30] information through and study captures as well as fecal samples. Speaker 5: I'm just super curious about what it was like following the Heller monkeys and spending literally all day with them. You, Speaker 4: I started to go insane. You actually do. Um, no, it was a really profound life experience for sure. And I couldn't have designed a better project to be part of. Like if I had designed my dream project, it would have been this project. When I started this project, I didn't speak Spanish and [00:05:00] every single person in my team only spoke Spanish, so I learned Spanish very fast. But during the process of learning a second language, you have this inability to completely express yourself and it kind of makes you go insane. And then when you couple that with standing in the middle of like a really humid forest, you know, surrounded by mosquitoes and following monkeys running through the canopy. I got you about month five I think, and I realized that I started to go insane. [00:05:30] When I yelled at an ant out loud, I paused and just laughed hysterically to myself and realize that like this is the point where like I've reached my mental break. Then I'm yelling at ants and I need to get to a city as soon as possible. Speaker 2: Okay. Our guest today on spectrum is Tony Bodhi Hickerson, but she answers to Tony Bodhi in the next, she talks about her idea for a dolphin stone. [00:06:00] This is k a l x Berkeley. Speaker 4: And what do you do with the dolphins? Uh, the Dolphin project, uh, is not a field project, unfortunately at the moment. It's an education campaign for the international mantle project, which is responsible for all dolphin safe tuna that you've ever seen as well as the documentary, the cove. So they're very avid group on [inaudible]. [00:06:30] And so I was putting together a campaign to try and inspire people that they're really intense creatures and why maybe we should respect them. Speaker 5: You tell us a little bit about those abilities and why they're so intense. Speaker 4: There are three groups of mammals that have large brains that's great. Apes, elephants and marine mammals. And the dolphins came from a very different evolutionary path. So they have different [00:07:00] structures, which is also really interesting. They don't have the prefrontal Cortex, which is what we tend to associate with being human, the sort of emotional side of being human. But they have a very intense limbic system, which is also associated with emotions and bonding behavior and sexual behavior. Dolphins have sort of this mixed reputation of being very kind of aggressive and also being really altruistic almost in their actions. [00:07:30] So looking at not only the hard facts of the biological side of things of like what structures they have and what those abilities are, but also case studies of look at these sort of altruistic behaviors. So their ability to perceive the world around them and to react in an emotional state is potentially really profound. Speaker 5: And um, in your study to sort of understand all the ways that the Dolphin perceives the world and the way that it often feels these things, are you looking at the structures in their brains and seeing [00:08:00] the corresponding place where these thought processes and these perceptions happen? Or are you just observing behavior or are you doing both? Speaker 4: Well, hopefully both. So I'm currently designing a project, which is hopefully gonna do exactly what you just said. Our tools at the moment are very limited, especially because we want to be as noninvasive as possible. Animals don't react in captivity the way that they react in the wild. And obviously they don't have the same space or social structure to be able to do the same sorts of things. [00:08:30] There is an up and coming technology that I hope to apply to this sort of research which would allow biological data to be recorded in real time and it would be completely noninvasive. It would be almost like a sticker, so there'd be no puncturing. There would be no need for captivity. Hopefully we could even apply it with minimal stress to the animal and with that we could have gps data body, we could potentially record the vibrations from their echolocation [00:09:00] and also neurological data and this would be the first information of its kind to be able to correlate if there's an approach or an affiliative behavior between two individuals, what areas of their brain are actually being, you know, lit up and that could really profoundly affect what we know about their structure. Speaker 4: Yeah, that that is sounds really exciting. So it would be noninvasive. Do you know how that works? That must be really amazing. The technology that I'm, I'm hoping to work with [00:09:30] is a flexible microchip and I'm hoping to be working with some of the innovators to make it appliable to dolphins and something that would stick for up to a month. They should scan very quickly, so that is a restraint. I don't know as much of the engineering side of it because I'm not as much tech, but from my conversations with the people developing it, it seems like it might not be up to use for a year or two, but hopefully eventually we'll get [00:10:00] there and we'll have a better understanding of how one of the smartest animals on the planet. Thanks. Are other people currently doing anything more invasive? Captivity can be a very invasive process. How animals and captivity get in captivity are often from Dolphin Slaughters, which kill hundreds of their fellow pod mates to get a handful of dolphins because a live dolphin that is pristine, [00:10:30] you know mark free that goes into entertainment or goes into a laboratory studies. They get taken out and they get sold for hundreds of thousands of dollars and the rest of them get slaughtered and sold into the meat markets. Speaker 6: Mm MM. Speaker 3: You are listening to spectrum on k a l x Berkeley. Our guest today is Tony Bow-tie Hickerson. Tony is a zoologist. In the next segment she talks about diagnosing Alzheimer's disease. Speaker 4: [00:11:00] I actually wanted to ask you a little bit about the work you're doing with Alzheimer's and dice diagnostic work. Could you maybe tell us a little bit about how the process of diagnosing Alzheimer's works currently and what you're hoping to change about that? Well, there really isn't much in terms of diagnosis that's out for the general public. What I'm actually attempting to do, and initially it was for my own curiosity and you know obviously see the potential for other people to use it as [00:11:30] well. I wanted to test myself on this gene. So there is a gene called apoe e and there are three expressions of it and they account for about 95% of all Hymers, one of these types of accounts for 50% of all hammers. I can essentially locate this gene snippet out of the enormous strand of DNA and then look at their two spots where [00:12:00] the nucleotide is a certain sequence that I can tell you. Speaker 4: If that is type one, two or three of that apathy and off of that, they're very strong statistics that will tell you that you have a very high likelihood or very low likelihood of getting Alzheimer's by a certain age. And it's sort of a spectrum due to the fact that we're deployed. So we have two copies of this gene. So if you have this like really strong negative version and one positive version, you will [00:12:30] have later onset Ohio Hymers. Then if you have two really negative versions, but there are really strong numbers that tell us what your likelihood is. But what I would like to do is to make it something that's very accessible for everyone. I don't want to produce this and market it as some expensive tests that's going to just perpetuate this whole medical debt system. I want this to be something that people can access and know for themselves to be able to plan [00:13:00] for their own future and to be able to take care of themselves and their family members more effectively and responsibly. Speaker 4: So it's pretty similar to the aggressive cancer testing would you say? Or? Um, yeah, it's fairly similar. I haven't looked exactly at that one to see. I believe it is also a snip, which is like this single nucleotide change. So it should be very similar. Do you want to tell us a little bit about the process of you sort of isolating this gene? Did you go through and read the papers [00:13:30] and see that this gene was associated with it and develop the processes snippet on your own or I'm in the process of developing the process to snippet. So right now I'm troubleshooting the primer. So the, the molecule that you use to actually cut the DNA, what I have is currently binding to itself. So it is also binding to the site that I want it to, but it's also binding to itself. So I'm trying to sort that issue out. Speaker 4: It's a process that needs to be critiqued a bit before. I'm willing to, you know, expose more [00:14:00] people to the answers cause I want to make sure that it is very accurate before I would to give someone those sorts of answers. You're currently doing some form of genetic screening and you previously did all of these behavioral studies. It's quite a transition. So how, how did you make that transition? Well they're both in principle based on cognition, mental abilities and so all Hymers is the degradation of cognitive abilities, the degradation of being able to recall information as well as [00:14:30] the breakdown of even motor skills and language skills and so that is profoundly interesting to me to to understand where and how cognitive abilities act and then to understand how they're dismantled is the cycle of, of the process of understanding exactly how things work. A lot of times we figure out what parts of the brain do what based on lesion studies, which is causing and disruption. Speaker 4: The initial draw [00:15:00] to this was for my own curiosity. And that was sparked because my father has severe dementia. So I wanted to know for him, is this all Hymers or is it something environmental? And so I want to develop a test for him, for myself and for the public to know what's their likelihood so that they can plan for the future. Are there other differentiating factors you could look at as well besides this, besides this gene? So the gene is pretty profound and [00:15:30] it's significance in whether or not people get all hammers. But there's, there's also, you know, of course a lot of different factors and I should mention that like echoey is a specific kind of all hammers. It's not early onset and not all dementia is Alzheimer's. There's lots of ways to get dementia in old age. So this isn't like a yes, no test. Speaker 4: If you have a really great diagnostic and it looks like you're clear for this, it doesn't mean that when you hit 80 that you're not gonna have problems [00:16:00] still. You still have to take care of yourself. And a lot of studies have shown that simple things and everyone says this, but simple things like diet and exercise. If you exercise on a regular basis, you can break down a lot of these corrosive molecules that cause a lot of mental problems, cause a lot of cardiovascular problems and you have to keep your metabolism up to deal with this and your body will also, you know, work to heal itself. It's just really profound what control you have over your future. [00:16:30] Like I don't want to give people this test and say you're doing, I feel that you two have a lot more control than a lot of people want to admit over the future. And so take responsibility for yourself and take care of your body. Go exercise and eat well and have lots of friends and learn new languages and go travel. See the world Speaker 2: spectrum is a science and technology show on KALX Berkeley. Our guest [00:17:00] today is Tony Bodhi Hickerson in the next segment that Tony talks about, the new Berkeley Bio lab. Speaker 4: So you're involved in a biohacker space. Uh, yes. So actually as of last weekend we moved into a space in Valeho which is my n when the other core members lab on the, hopefully we will be also opening a space [00:17:30] in Berkeley eventually, but for now we're in relay hope and it's essentially like a hacker space, but it's in biotech in general and you pay a membership and you have access to the lab and the materials to do your own research, detached from corporate biases and the strains of academia. So we provide a space in the community to kind of teach each other and [00:18:00] to work in and we allow real hard science to take place and sort of a pioneer setting. What's the name of it and how does it compare it to bio curious and some of the other spaces in the bay area? Speaker 4: Sure. The name of the lab is going to be Berkeley bio labs. Some of the other entities that will be occurring within this lab is a June cell technologies. We're trying to be much more accessible in that our membership [00:18:30] is only going to be $100 a month, whereas a lot of other bio spaces are $2,000 and up a month. I think that having more spaces isn't necessarily a bad thing. We tend to be a little bit more focused on regenerative medicine and stem cell research, so people who are more focused along that lines might be more attracted to work with us, but certainly weren't. We're not discriminating against people who aren't in stem cell research or regenerative medicine. That's just what we tend to do. I shouldn't ask you if you could [00:19:00] tell us a little bit more about the projects that are happening in the space now. Speaker 4: At the moment, we haven't even opened up yet. We were literally still moving all of the giant centrifuges and automated robots. And so right now I'm is my project as well as John's London, which is one of the founding members of the biohacker lab and he works in regenerative medicine and stem cells. [00:19:30] And once we kind of get settled and open our doors, we'll hopefully be screening lots of potential innovators to come and join our project and not necessarily his project but you know, whatever inspires them to try and you know, make a difference. And what will that screening process look like? It'll honestly be very personal. We're going to just meet with people one on one and see what they're interested in doing, what they have done and what they want to see in the future. It's much more about the people and [00:20:00] their drive to do something than the letters after their name. Speaker 4: We all feel that someone who's really driven to take the four or five years after a bachelor's and do their own research potentially has a lot more to offer than someone who might not know what they want to do in his just signing up for pastry. Cause they feel like it's the next step. So we're definitely open to pioneers, innovators and people who are willing to scrap to make a change. How are you getting the word out about the a space? [00:20:30] Well, actually the, the first thing that has happened so far on the 24th I believe it was, we had a paper written about us in nature. And so that was the first real publicity, and this is the second. So the article was called biotechnology independent streak. If anyone cares to look it up in the July 24th issue, it's gotta be super expensive to have all of the high mated robots and the giant centrifuge. Speaker 4: How are you financing [00:21:00] the space? All of the equipment is already owned by John. He's been working in biotech for quite some time and it has accumulated a very impressive stock of machinery and equipment and he's more than happy to share, to enable other people. He's been really phenomenal and assisting me and getting into a lab space, she's really enabled me to be able to do research that I would never be able to do on my own. And he's doing that for hopefully a lot of other people and so [00:21:30] I would hope to perpetuate that and help people get into it and start making a difference. What do you anticipate the future of the hackerspace pain? Well, we hope that we find lots of driven people who want to come and we are overflowing with scientists until we need to open up another space. I would love to see this be a scientific movement. Speaker 4: Science is all about curiosity. It's about having a question and figuring out how to find the answer and I think that that's [00:22:00] something in our education system that a lot of times is not really taught. People are taught facts, they're not taught. How do you figure facts out? You know? It's not about memorization. It's about teaching yourself how to think. How did you get into science? I have always been profoundly curious, but actually I started out as an art major and about two and a half years in I got called into my advisor's [00:22:30] office and I said, you can't take any more science classes. Told me you filled up all your electives and another semester. And if you take another science class, then we're going to kick you out of the fine arts school. So I said, okay. And I put in an application at another university and switched into science because I thought it was completely absurd that they would hinder me from taking science classes, but it was just a curiosity to understand how [00:23:00] the molecular and biological world works. Understand, you know, how life happens and how stars are born. It's something that I don't understand why every single person doesn't have this profound emotional response to understanding all Tony, thanks for joining. Yes, thank you. Speaker 2: Oh, [inaudible]. If you can not always catch spectrum broadcasts, know that shows are archived [00:23:30] on iTunes university, we have created a simple link to the archive just for you. The link is tiny url.com/calyx spectrum. No, a few of the science and technology events happening locally over the next two weeks. Rick Karnofsky and I present the calendar. Speaker 3: Tuesday. August 27th the UC Berkeley Botanical Gardens [00:24:00] will host a guided butterfly walk. Join Sally Levinson, the gardens resident caterpillar lady on a walk through the amazing collections of the botanical garden in search of butterflies to register for a butterfly walk, which is free with admission email garden@berkeley.edu the butterfly walk will be held from three to 4:00 PM on Tuesday, August 27th at the UC Berkeley Botanical Gardens. At this month, [00:24:30] actual science, you can learn how the properties of diamonds are uniquely suited for scientific research. Christine beavers is a research scientist based at the advanced light source at Lawrence Berkeley National Lab. Her specialty is crystallography, which is the determination of 3d structures of molecules from crystals using x-rays. Actual science will be on Thursday, August 29th at 6:00 PM [00:25:00] at actual cafe six three three four San Pablo Avenue in Oakland and mission is free. UC Berkeley is holding its first monthly blood drive of the school year on August 29th you can make an appointment online, but walk-ins are also welcome. Speaker 3: You are eligible to donate if you are in good health way, at least 110 pounds and are 17 years or older. The blood drive will be on Thursday, August 29th in the Anna had [00:25:30] alumni house on the UC Berkeley campus. It will last from 9:00 AM to 3:00 PM you can make an appointment or find more information at the website. Red cross.org using the sponsor code you see be wonder fest and ask a scientist present the neuroscience of magic on Wednesday, September 4th at the [inaudible] street food park, 48 [00:26:00] 11th street in San Francisco. You CSF professor of neuroscience, Adam Gazzaley and the comedy magician, Robert Strong. We'll lead discussions from ancient conjurers t quick handed con artists, two big ticket Las Vegas illusionists magicians. Throughout the ages, I've been expertly manipulating human at attention and perception to dazzle and delight us. [00:26:30] Of course, you know that the phenomenon of cognitive and sensory illusions are responsible for the magic, but you've got to admit it still kind of freaks you out when some guy in a top hat defies the of nature right in front of your eyes. The event is free. Now, two news stories. Speaker 3: Berkeley News Center reports a new theory by fluid dynamics experts at the University of California Berkeley shows how Zombie vorticies [00:27:00] help lead to the birth of a new star reporting in the journal Physical Review Letters, a team led by computational physicist Philip Marcus shows how variations in gas density led to instability, which generates the whirlpool like vorticies needed for stars to form. The Zombie reference is an astronomical nod to pop culture and because of the so called dead zones in which these vorticies exist, this new model has caught the [00:27:30] attention of Marcus's colleagues at UC Berkeley, including Richard Klein, adjunct professor of astronomy and fellow star formation expert, Christopher McKee, UC Berkeley professor of physics and astronomy. They were not part of the work described in physical review letters but are collaborating with Marcus to put the Zombie vorticies through more tests. Science daily reports the identification of what may be the earliest known [00:28:00] biomarker associated with the risk of developing Alzheimer's disease. Speaker 3: The results suggest that this novel potential biomarker is present in cerebral spinal fluid at least a decade before signs of dementia manifest. If our initial findings can be replicated by other laboratories, the results will change the way we currently think about the causes of Alzheimer's Disease said Dr Ramon true? Yes. Research professor [00:28:30] at the CSIC Institute of Biomedical Research of Barcelona and lead author of the study that was published in annals of neurology. This discovery may enable us to search for more effective treatments that can be administered during the preclinical stage. These C S I c researchers demonstrated that a decrease in the content of micro chondrial DNA in cerebral spinal fluid may be a preclinical indicator [00:29:00] for Alzheimer's disease. Furthermore, there may be a direct causal relationship Speaker 6: [inaudible].Speaker 1: The music hub during this show was written and produced by Alex Simon. Thank you for listening to spectrum. If you have comments about the show, please send them to us via email. Address [00:29:30] is spectrum dot k. Alright. yahoo.com join us in two weeks at this same time. [inaudible]. See acast.com/privacy for privacy and opt-out information.

Zoologist Toni Bodi is currently developing a genomic diagnostic screen for Alzheimer's disease and is a founding member of the Berkeley Bio Labs new bio hacker space. Nature magazine.TranscriptSpeaker 1: Spectrum's next. Speaker 2: Aw. [inaudible] [inaudible] [inaudible] [inaudible] [inaudible]. Speaker 1: Welcome to spectrum the science [00:00:30] and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hi and good afternoon. My name is Brad Swift. I'm the host of today's show. Our guest is Tony Bodhi Hickerson, a zoologist who was part of a cognitive study of howler monkeys in Mexico. Tony is trying to organize a noninvasive [00:01:00] dolphin study in the wild using wireless network technology. She is currently developing a genomic diagnostic screen for Alzheimer's disease and is a founding member of the Berkeley bio labs, a new bio hackerspace. Tony talks about cognition, Alzheimer's disease, and creating a scientific community resource in the bay area. Rick Karnofsky and Renee Rau interview Tony on this edition of spectrum. Speaker 4: So welcome to spectrum. [00:01:30] I'm Rick Karnofsky here with Brad swift and Renee Rao. Our guest today on spectrum is Tony Bodhi, Hickerson and zoologist. Welcome to spectrum. Thank you for having me. Can you give us a little bit of a description of what you work on? Kind of a brief overview for the audience. That cognition is essentially the ability to receive and process information and the most abstract form. And we kind of think of it as mental processes, which can be both conscious and subconscious. [00:02:00] And so I do research on cognitive abilities of wildlife and at the moment I'm also working on an application in humans. What wildlife do you look at? Um, well I have looked at primates and I've been also involved in a dolphin project. So high functioning mammals. And how do you assess their cognitive abilities? Well, you can do behavioral studies, which is what I primarily do. Speaker 4: And of course just looking at the anatomy as well. So [00:02:30] I try to be as noninvasive as possible. I don't work in a lab with monkeys in a cage. I actually work in the wilderness and follow monkeys around all day. So where do you do that? I was doing that in Mexico for my last study with seven months and from Sunup I watched the sun come up and uh, the howler monkeys, which is a species that I was working on would call in the morning. That's how we'd find them. So we trek through the jungle and find them and then start our study. And it would usually last, well it would last until sundown. So depending on how many hours a like we had [00:03:00] [inaudible] Speaker 5: can you just walk us through what the study was and what you looked at in the howler monkeys and how you interpreted it? Speaker 4: Well, this study, I was a, the head field managers, so it wasn't my particular study, but I was managing all the data collection and uh, we were looking at two different species of Holler monkey. And they're hybrids. So there's hybrid zone in Mexico where both of these species, which we believe based on genetic evidence have been separated for about 3 million [00:03:30] years. They have different number of sex chromosomes. They're very morphologically different, are coming together and meeting successfully. They also have very different social structures and one group tends to be far more aggressive than the other one is much more communal. It has large groups up to 25 30 and the other one usually has three to five. So to see how behaviorly they come together and genetically they come together because in one cross if you have a female of a and a male of B, they can [00:04:00] have an offspring. But if you inverse it they cannot. So it's really interesting also genetically to see how things recombine. What kinds of data did you take? Oh, we took auditory, so we, they're hollow monkeys. So we had all their calls, which it changes from group to group and obviously from species to species. We also took a lot of behavioral information, affiliative, so like affection and aggressive behavior, like attacks and genetic [00:04:30] information through and study captures as well as fecal samples. Speaker 5: I'm just super curious about what it was like following the Heller monkeys and spending literally all day with them. You, Speaker 4: I started to go insane. You actually do. Um, no, it was a really profound life experience for sure. And I couldn't have designed a better project to be part of. Like if I had designed my dream project, it would have been this project. When I started this project, I didn't speak Spanish and [00:05:00] every single person in my team only spoke Spanish, so I learned Spanish very fast. But during the process of learning a second language, you have this inability to completely express yourself and it kind of makes you go insane. And then when you couple that with standing in the middle of like a really humid forest, you know, surrounded by mosquitoes and following monkeys running through the canopy. I got you about month five I think, and I realized that I started to go insane. [00:05:30] When I yelled at an ant out loud, I paused and just laughed hysterically to myself and realize that like this is the point where like I've reached my mental break. Then I'm yelling at ants and I need to get to a city as soon as possible. Speaker 2: Okay. Our guest today on spectrum is Tony Bodhi Hickerson, but she answers to Tony Bodhi in the next, she talks about her idea for a dolphin stone. [00:06:00] This is k a l x Berkeley. Speaker 4: And what do you do with the dolphins? Uh, the Dolphin project, uh, is not a field project, unfortunately at the moment. It's an education campaign for the international mantle project, which is responsible for all dolphin safe tuna that you've ever seen as well as the documentary, the cove. So they're very avid group on [inaudible]. [00:06:30] And so I was putting together a campaign to try and inspire people that they're really intense creatures and why maybe we should respect them. Speaker 5: You tell us a little bit about those abilities and why they're so intense. Speaker 4: There are three groups of mammals that have large brains that's great. Apes, elephants and marine mammals. And the dolphins came from a very different evolutionary path. So they have different [00:07:00] structures, which is also really interesting. They don't have the prefrontal Cortex, which is what we tend to associate with being human, the sort of emotional side of being human. But they have a very intense limbic system, which is also associated with emotions and bonding behavior and sexual behavior. Dolphins have sort of this mixed reputation of being very kind of aggressive and also being really altruistic almost in their actions. [00:07:30] So looking at not only the hard facts of the biological side of things of like what structures they have and what those abilities are, but also case studies of look at these sort of altruistic behaviors. So their ability to perceive the world around them and to react in an emotional state is potentially really profound. Speaker 5: And um, in your study to sort of understand all the ways that the Dolphin perceives the world and the way that it often feels these things, are you looking at the structures in their brains and seeing [00:08:00] the corresponding place where these thought processes and these perceptions happen? Or are you just observing behavior or are you doing both? Speaker 4: Well, hopefully both. So I'm currently designing a project, which is hopefully gonna do exactly what you just said. Our tools at the moment are very limited, especially because we want to be as noninvasive as possible. Animals don't react in captivity the way that they react in the wild. And obviously they don't have the same space or social structure to be able to do the same sorts of things. [00:08:30] There is an up and coming technology that I hope to apply to this sort of research which would allow biological data to be recorded in real time and it would be completely noninvasive. It would be almost like a sticker, so there'd be no puncturing. There would be no need for captivity. Hopefully we could even apply it with minimal stress to the animal and with that we could have gps data body, we could potentially record the vibrations from their echolocation [00:09:00] and also neurological data and this would be the first information of its kind to be able to correlate if there's an approach or an affiliative behavior between two individuals, what areas of their brain are actually being, you know, lit up and that could really profoundly affect what we know about their structure. Speaker 4: Yeah, that that is sounds really exciting. So it would be noninvasive. Do you know how that works? That must be really amazing. The technology that I'm, I'm hoping to work with [00:09:30] is a flexible microchip and I'm hoping to be working with some of the innovators to make it appliable to dolphins and something that would stick for up to a month. They should scan very quickly, so that is a restraint. I don't know as much of the engineering side of it because I'm not as much tech, but from my conversations with the people developing it, it seems like it might not be up to use for a year or two, but hopefully eventually we'll get [00:10:00] there and we'll have a better understanding of how one of the smartest animals on the planet. Thanks. Are other people currently doing anything more invasive? Captivity can be a very invasive process. How animals and captivity get in captivity are often from Dolphin Slaughters, which kill hundreds of their fellow pod mates to get a handful of dolphins because a live dolphin that is pristine, [00:10:30] you know mark free that goes into entertainment or goes into a laboratory studies. They get taken out and they get sold for hundreds of thousands of dollars and the rest of them get slaughtered and sold into the meat markets. Speaker 6: Mm MM. Speaker 3: You are listening to spectrum on k a l x Berkeley. Our guest today is Tony Bow-tie Hickerson. Tony is a zoologist. In the next segment she talks about diagnosing Alzheimer's disease. Speaker 4: [00:11:00] I actually wanted to ask you a little bit about the work you're doing with Alzheimer's and dice diagnostic work. Could you maybe tell us a little bit about how the process of diagnosing Alzheimer's works currently and what you're hoping to change about that? Well, there really isn't much in terms of diagnosis that's out for the general public. What I'm actually attempting to do, and initially it was for my own curiosity and you know obviously see the potential for other people to use it as [00:11:30] well. I wanted to test myself on this gene. So there is a gene called apoe e and there are three expressions of it and they account for about 95% of all Hymers, one of these types of accounts for 50% of all hammers. I can essentially locate this gene snippet out of the enormous strand of DNA and then look at their two spots where [00:12:00] the nucleotide is a certain sequence that I can tell you. Speaker 4: If that is type one, two or three of that apathy and off of that, they're very strong statistics that will tell you that you have a very high likelihood or very low likelihood of getting Alzheimer's by a certain age. And it's sort of a spectrum due to the fact that we're deployed. So we have two copies of this gene. So if you have this like really strong negative version and one positive version, you will [00:12:30] have later onset Ohio Hymers. Then if you have two really negative versions, but there are really strong numbers that tell us what your likelihood is. But what I would like to do is to make it something that's very accessible for everyone. I don't want to produce this and market it as some expensive tests that's going to just perpetuate this whole medical debt system. I want this to be something that people can access and know for themselves to be able to plan [00:13:00] for their own future and to be able to take care of themselves and their family members more effectively and responsibly. Speaker 4: So it's pretty similar to the aggressive cancer testing would you say? Or? Um, yeah, it's fairly similar. I haven't looked exactly at that one to see. I believe it is also a snip, which is like this single nucleotide change. So it should be very similar. Do you want to tell us a little bit about the process of you sort of isolating this gene? Did you go through and read the papers [00:13:30] and see that this gene was associated with it and develop the processes snippet on your own or I'm in the process of developing the process to snippet. So right now I'm troubleshooting the primer. So the, the molecule that you use to actually cut the DNA, what I have is currently binding to itself. So it is also binding to the site that I want it to, but it's also binding to itself. So I'm trying to sort that issue out. Speaker 4: It's a process that needs to be critiqued a bit before. I'm willing to, you know, expose more [00:14:00] people to the answers cause I want to make sure that it is very accurate before I would to give someone those sorts of answers. You're currently doing some form of genetic screening and you previously did all of these behavioral studies. It's quite a transition. So how, how did you make that transition? Well they're both in principle based on cognition, mental abilities and so all Hymers is the degradation of cognitive abilities, the degradation of being able to recall information as well as [00:14:30] the breakdown of even motor skills and language skills and so that is profoundly interesting to me to to understand where and how cognitive abilities act and then to understand how they're dismantled is the cycle of, of the process of understanding exactly how things work. A lot of times we figure out what parts of the brain do what based on lesion studies, which is causing and disruption. Speaker 4: The initial draw [00:15:00] to this was for my own curiosity. And that was sparked because my father has severe dementia. So I wanted to know for him, is this all Hymers or is it something environmental? And so I want to develop a test for him, for myself and for the public to know what's their likelihood so that they can plan for the future. Are there other differentiating factors you could look at as well besides this, besides this gene? So the gene is pretty profound and [00:15:30] it's significance in whether or not people get all hammers. But there's, there's also, you know, of course a lot of different factors and I should mention that like echoey is a specific kind of all hammers. It's not early onset and not all dementia is Alzheimer's. There's lots of ways to get dementia in old age. So this isn't like a yes, no test. Speaker 4: If you have a really great diagnostic and it looks like you're clear for this, it doesn't mean that when you hit 80 that you're not gonna have problems [00:16:00] still. You still have to take care of yourself. And a lot of studies have shown that simple things and everyone says this, but simple things like diet and exercise. If you exercise on a regular basis, you can break down a lot of these corrosive molecules that cause a lot of mental problems, cause a lot of cardiovascular problems and you have to keep your metabolism up to deal with this and your body will also, you know, work to heal itself. It's just really profound what control you have over your future. [00:16:30] Like I don't want to give people this test and say you're doing, I feel that you two have a lot more control than a lot of people want to admit over the future. And so take responsibility for yourself and take care of your body. Go exercise and eat well and have lots of friends and learn new languages and go travel. See the world Speaker 2: spectrum is a science and technology show on KALX Berkeley. Our guest [00:17:00] today is Tony Bodhi Hickerson in the next segment that Tony talks about, the new Berkeley Bio lab. Speaker 4: So you're involved in a biohacker space. Uh, yes. So actually as of last weekend we moved into a space in Valeho which is my n when the other core members lab on the, hopefully we will be also opening a space [00:17:30] in Berkeley eventually, but for now we're in relay hope and it's essentially like a hacker space, but it's in biotech in general and you pay a membership and you have access to the lab and the materials to do your own research, detached from corporate biases and the strains of academia. So we provide a space in the community to kind of teach each other and [00:18:00] to work in and we allow real hard science to take place and sort of a pioneer setting. What's the name of it and how does it compare it to bio curious and some of the other spaces in the bay area? Speaker 4: Sure. The name of the lab is going to be Berkeley bio labs. Some of the other entities that will be occurring within this lab is a June cell technologies. We're trying to be much more accessible in that our membership [00:18:30] is only going to be $100 a month, whereas a lot of other bio spaces are $2,000 and up a month. I think that having more spaces isn't necessarily a bad thing. We tend to be a little bit more focused on regenerative medicine and stem cell research, so people who are more focused along that lines might be more attracted to work with us, but certainly weren't. We're not discriminating against people who aren't in stem cell research or regenerative medicine. That's just what we tend to do. I shouldn't ask you if you could [00:19:00] tell us a little bit more about the projects that are happening in the space now. Speaker 4: At the moment, we haven't even opened up yet. We were literally still moving all of the giant centrifuges and automated robots. And so right now I'm is my project as well as John's London, which is one of the founding members of the biohacker lab and he works in regenerative medicine and stem cells. [00:19:30] And once we kind of get settled and open our doors, we'll hopefully be screening lots of potential innovators to come and join our project and not necessarily his project but you know, whatever inspires them to try and you know, make a difference. And what will that screening process look like? It'll honestly be very personal. We're going to just meet with people one on one and see what they're interested in doing, what they have done and what they want to see in the future. It's much more about the people and [00:20:00] their drive to do something than the letters after their name. Speaker 4: We all feel that someone who's really driven to take the four or five years after a bachelor's and do their own research potentially has a lot more to offer than someone who might not know what they want to do in his just signing up for pastry. Cause they feel like it's the next step. So we're definitely open to pioneers, innovators and people who are willing to scrap to make a change. How are you getting the word out about the a space? [00:20:30] Well, actually the, the first thing that has happened so far on the 24th I believe it was, we had a paper written about us in nature. And so that was the first real publicity, and this is the second. So the article was called biotechnology independent streak. If anyone cares to look it up in the July 24th issue, it's gotta be super expensive to have all of the high mated robots and the giant centrifuge. Speaker 4: How are you financing [00:21:00] the space? All of the equipment is already owned by John. He's been working in biotech for quite some time and it has accumulated a very impressive stock of machinery and equipment and he's more than happy to share, to enable other people. He's been really phenomenal and assisting me and getting into a lab space, she's really enabled me to be able to do research that I would never be able to do on my own. And he's doing that for hopefully a lot of other people and so [00:21:30] I would hope to perpetuate that and help people get into it and start making a difference. What do you anticipate the future of the hackerspace pain? Well, we hope that we find lots of driven people who want to come and we are overflowing with scientists until we need to open up another space. I would love to see this be a scientific movement. Speaker 4: Science is all about curiosity. It's about having a question and figuring out how to find the answer and I think that that's [00:22:00] something in our education system that a lot of times is not really taught. People are taught facts, they're not taught. How do you figure facts out? You know? It's not about memorization. It's about teaching yourself how to think. How did you get into science? I have always been profoundly curious, but actually I started out as an art major and about two and a half years in I got called into my advisor's [00:22:30] office and I said, you can't take any more science classes. Told me you filled up all your electives and another semester. And if you take another science class, then we're going to kick you out of the fine arts school. So I said, okay. And I put in an application at another university and switched into science because I thought it was completely absurd that they would hinder me from taking science classes, but it was just a curiosity to understand how [00:23:00] the molecular and biological world works. Understand, you know, how life happens and how stars are born. It's something that I don't understand why every single person doesn't have this profound emotional response to understanding all Tony, thanks for joining. Yes, thank you. Speaker 2: Oh, [inaudible]. If you can not always catch spectrum broadcasts, know that shows are archived [00:23:30] on iTunes university, we have created a simple link to the archive just for you. The link is tiny url.com/calyx spectrum. No, a few of the science and technology events happening locally over the next two weeks. Rick Karnofsky and I present the calendar. Speaker 3: Tuesday. August 27th the UC Berkeley Botanical Gardens [00:24:00] will host a guided butterfly walk. Join Sally Levinson, the gardens resident caterpillar lady on a walk through the amazing collections of the botanical garden in search of butterflies to register for a butterfly walk, which is free with admission email garden@berkeley.edu the butterfly walk will be held from three to 4:00 PM on Tuesday, August 27th at the UC Berkeley Botanical Gardens. At this month, [00:24:30] actual science, you can learn how the properties of diamonds are uniquely suited for scientific research. Christine beavers is a research scientist based at the advanced light source at Lawrence Berkeley National Lab. Her specialty is crystallography, which is the determination of 3d structures of molecules from crystals using x-rays. Actual science will be on Thursday, August 29th at 6:00 PM [00:25:00] at actual cafe six three three four San Pablo Avenue in Oakland and mission is free. UC Berkeley is holding its first monthly blood drive of the school year on August 29th you can make an appointment online, but walk-ins are also welcome. Speaker 3: You are eligible to donate if you are in good health way, at least 110 pounds and are 17 years or older. The blood drive will be on Thursday, August 29th in the Anna had [00:25:30] alumni house on the UC Berkeley campus. It will last from 9:00 AM to 3:00 PM you can make an appointment or find more information at the website. Red cross.org using the sponsor code you see be wonder fest and ask a scientist present the neuroscience of magic on Wednesday, September 4th at the [inaudible] street food park, 48 [00:26:00] 11th street in San Francisco. You CSF professor of neuroscience, Adam Gazzaley and the comedy magician, Robert Strong. We'll lead discussions from ancient conjurers t quick handed con artists, two big ticket Las Vegas illusionists magicians. Throughout the ages, I've been expertly manipulating human at attention and perception to dazzle and delight us. [00:26:30] Of course, you know that the phenomenon of cognitive and sensory illusions are responsible for the magic, but you've got to admit it still kind of freaks you out when some guy in a top hat defies the of nature right in front of your eyes. The event is free. Now, two news stories. Speaker 3: Berkeley News Center reports a new theory by fluid dynamics experts at the University of California Berkeley shows how Zombie vorticies [00:27:00] help lead to the birth of a new star reporting in the journal Physical Review Letters, a team led by computational physicist Philip Marcus shows how variations in gas density led to instability, which generates the whirlpool like vorticies needed for stars to form. The Zombie reference is an astronomical nod to pop culture and because of the so called dead zones in which these vorticies exist, this new model has caught the [00:27:30] attention of Marcus's colleagues at UC Berkeley, including Richard Klein, adjunct professor of astronomy and fellow star formation expert, Christopher McKee, UC Berkeley professor of physics and astronomy. They were not part of the work described in physical review letters but are collaborating with Marcus to put the Zombie vorticies through more tests. Science daily reports the identification of what may be the earliest known [00:28:00] biomarker associated with the risk of developing Alzheimer's disease. Speaker 3: The results suggest that this novel potential biomarker is present in cerebral spinal fluid at least a decade before signs of dementia manifest. If our initial findings can be replicated by other laboratories, the results will change the way we currently think about the causes of Alzheimer's Disease said Dr Ramon true? Yes. Research professor [00:28:30] at the CSIC Institute of Biomedical Research of Barcelona and lead author of the study that was published in annals of neurology. This discovery may enable us to search for more effective treatments that can be administered during the preclinical stage. These C S I c researchers demonstrated that a decrease in the content of micro chondrial DNA in cerebral spinal fluid may be a preclinical indicator [00:29:00] for Alzheimer's disease. Furthermore, there may be a direct causal relationship Speaker 6: [inaudible].Speaker 1: The music hub during this show was written and produced by Alex Simon. Thank you for listening to spectrum. If you have comments about the show, please send them to us via email. Address [00:29:30] is spectrum dot k. Alright. yahoo.com join us in two weeks at this same time. [inaudible]. Hosted on Acast. See acast.com/privacy for more information.

Tempted by the fallacy of climbing the corporate ladder of success, Robert Strong worked for 15 years from to build a life of financial freedom. He found himself losing more of personal life with each promotion he was awarded. When Robert realized that working 75+ hours a week to build someone else's dream was taking him away from precious moments with his family – he decided there needed to be a change. He connected with a multi-level marketing opportunity and with no technical expertise was able to create a website promoting his new business. Seeking the guidance of those who had achieved the success that he sought, Robert was able to bring thousands of people to his site and successfully promote his business. Listen as he shares how he escaped the corporate pyramid scheme and give actionable steps for anyone else to do the same. Takeaways: “When one teaches two learn.” – Tweet This “When you start to creating results you start attracting people.” – Tweet This “It's not until the moment that you give up that you've truly failed.” – Tweet This “It's my responsibility to share any education I have with my MLM team.” – Tweet This “You need three things for success – a partner, a guide, and a strategy.” – Tweet This “If I wake up two hours before you then I have a two hour head start on the day.” – Tweet This “Knowledge is always shared in MLM. In corporate people share less to protect their jobs.” – Tweet This “Create your MLM strategy based on what you like to do, otherwise you won't do it long enough.” – Tweet This “Leaders in corporate only want to help you when you're not in a position to take their position.” – Tweet This   Full Post: http://goo.gl/wNmMc Catalyst Community: http://www.catalystmlm.com More Interviews: http://catalystmlm.com/category/interviews Connect on Facebook: http://www.facebook.com/catalystmlm Connect on Twitter: http://www.twitter.com/catalystmlm Connect on Instagram: http://instagram.com/catalystmlm Connect on Pinterest: http://www.pinterest.com/catalystmlm