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In this episode of Run the Numbers, CJ sits down with Dan Griggs, CFO of Intercom, to break down how finance leaders should think about pricing, forecasting, and resource allocation in the AI era. Dan explains why “it's not zero” is his guiding forecasting principle, how Intercom landed on 99 cents per AI resolution for Fin, and what it means to build an AI product that could eventually cannibalize a successful SaaS core. A candid look at managing uncertainty while still making bold bets.—SPONSORS:Brex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.ai—LINKS:Dan on LinkedIn: https://www.linkedin.com/in/dan-griggs-0970181/Intercom: https://www.intercom.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:Inside Rocket Companies: M&A, Metrics, and Mortgage Moats | Brian Brownhttps://youtu.be/ttedn4AULt8—TIMESTAMPS:00:00:00 Cold Open00:01:03 Intro to Dan Griggs and Intercom's AI Pivot00:02:45 From Ice Cream to SaaS: Early Finance Lessons00:04:19 Learning the Business by Living the Operations00:06:26 Why Operational Reality Shapes Better Forecasts00:08:00 “It's Not Zero”: Forecasting the Unknowable00:10:09 Scenario Planning, Ambiguity, and Psychological Safety00:11:23 Sponsors — Brex | Metronome | RightRev00:14:43 Keeping a Mental Model of Key Business Metrics00:16:15 Using Mental Math to Sanity-Check Forecasts00:17:28 Core Ratios Every CFO Uses to Vet Decisions00:19:13 The Burn-the-Boats Moment for Intercom's AI Pivot00:20:53 Why AI Was an Existential, Not Incremental, Bet00:22:21 Which SaaS Categories AI Can Fully Replace Work00:23:04 Why Finance Hasn't Had Its AI Moment Yet00:23:39 Sponsors — Rillet | Tabs | Abacum00:27:05 Why Fin Needed Outcome-Based Pricing00:28:59 The Tradeoff Behind $0.99 Per Resolution00:30:46 Why Support Conversations Vary in Complexity00:32:01 What Drives the Unit Economics of AI Resolutions00:33:08 How Intercom Chooses Models as Costs Fall00:35:19 Replacing Generic LLMs With Domain-Specific Models00:36:08 Selling an AI Product That Could Cannibalize the Core00:38:50 Founder CEOs Versus Professional CEOs00:41:47 Hiring Mistakes and Acting on Instincts00:44:28 Intercom's Finance Software Stack00:45:49 The Craziest Expense Request#RunTheNumbersPodcast #Intercom #AICustomerSupport #OutcomeBasedPricing #CFOInsights This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
* Mailbag! We asked, you delivered!* Email from Elie: Alternative mechanics to play in Barsaive?* Cortex -- https://www.cortexrpg.com/* Earthdawn: Age of Legend -- https://www.drivethrurpg.com/en/product/176986/earthdawn-the-age-of-legend-english* Earthdawn: Savage Worlds -- https://www.drivethrurpg.com/en/product/100174/earthdawn-player-s-guide-savage-worlds-edition* Also discussed: Cypher, Genesys* Problems with Horror marks as a concept (from player perspective)* Other active Earthdawn podcasts?* Email from Maggie: Changes to the Mad Passions' temples or shrines when they went mad?* Symbols and iconography of the Mad Passions from before the Scourge?* Email from Scott: Follow up to Mailbag 268 about Beast Spirits* Another Email from Maggie: T'skrang and Obsidimen as trans metaphors* Email from Simon: Many questions about the Gate Hound magic drain power* Range of chakta birds' Mental Assault power?* Range of the crakbill's paralyzing breath?* Is there a maximum Circle (0-thread) spell that a manticore can learn?* Constrict and Grab & Bite maneuvers for the porcupine snake and troll snake?* Engulf power from an air elemental?* Descriptions of true element kernels?* Awareness vs Perception (and limits of Awareness)?* Spending Karma on secret tests (especially Awareness)?Find and Follow:Email: edsgpodcast@gmail.comYouTube: https://www.youtube.com/@EDSGPodcastFind and follow Josh: https://linktr.ee/LoreMerchantGet product information, developer blogs, and more at www.fasagames.comFASA Games on Facebook: https://www.facebook.com/fasagamesincOfficial Earthdawn Facebook Group: https://www.facebook.com/groups/officialearthdawnFASA Games Discord Channel: https://discord.gg/uuVwS9uEarthdawn West Marches: https://discord.gg/hhHDtXW
Dr. David Eagleman, PhD, is a neuroscientist, bestselling author and professor at Stanford University. We discuss how to leverage the science of neuroplasticity to learn new skills and information and how accurate and false memories form and are forgotten. We also discuss time perception and why it speeds up or slows down depending on our age and stress level. We cover dreaming and the meaning of visual and other dream content. And we discuss the neuroscience of cultural and political polarization and how to remedy it. This episode provides science-based knowledge and practical tools you can use to enhance learning and better understand your experience of life in the past, present and future. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/offer Rorra: https://rorra.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) David Eagleman (00:02:35) Neuroplasticity & Learning; Cortex, Flexibility & Repurposing, Savantism (00:11:07) Sponsors: Mateina & Rorra (00:13:27) Specialization vs Diversification, Practice; Internet & Curiosity (00:22:05) Building a Well-Rounded Brain, Tool: Critical Thinking & Creativity (00:28:18) Neuroplasticity & Adults, Tools: Novelty & Challenge (00:32:41) Neuromodulators & Plasticity, Psychedelics; Directed Plasticity (00:38:50) Sponsor: AG1 (00:39:41) Building a Better Future Self, Tool: Ulysses Contract to Avoid Bad Behaviors (00:50:13) Brain Chatter, Aphantasia & Practice (00:56:57) Specialization vs Diverse Experience, Childhood & Brain (01:00:50) Space & Time Perception, Tool: Space-Time Bridging Meditation (01:06:17) Are We Good at Estimating Time?; Fear, Time & Memory (01:11:23) Sponsor: Lingo (01:12:53) Fearful Situations & Time Perception; Joyful Events & Novelty, Tool: Do Things Differently (01:18:56) Staying in the Present, Mental Illness & Time Domains, Addiction (01:27:09) Social Media, Addiction, Curiosity (01:30:51) Vision & Auditory Deficits, Sensory Substitution, Neosensory Wristband (01:35:26) Sponsor: Function (01:37:13) Sensory Reliance, Echolocation, Potato Head Theory, Sensory Addition (01:41:36) Why We Dream, Vision & Neuroplasticity, REM Sleep, Blindness (01:49:55) Victims, Fear, Memory Drift & Recall, Eyewitness Testimony & Jury Education (01:56:10) Kids vs Adults, Memory Manipulation; Photos (01:59:27) Polarization, In vs Out Groups, Empathy; Fairness (02:06:31) Polarization, Reward vs Punishment; Propaganda, Language, Complexification (02:19:27) Current Projects; Acknowledgements (02:21:44) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of Run the Numbers, CJ sits down with Maria Izurieta, CFO of Huntress, to unpack what it really means to lead finance as a connective tissue across the organization. Drawing on experience across VC-backed, PE-owned, and public companies, Maria shares how she balances impact versus perfection, builds trust through small wins, and helps teams move from transactional finance to insight-driven decision making. They dig into data transparency, centralized BI, partnering with sales and marketing on revenue, and why the best CFOs unblock friction instead of becoming the “no” department — all while bringing a deeply people-first lens to scale.—SPONSORS:Abacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/run—LINKS:Maria on LinkedIn: https://www.linkedin.com/in/maria-izurieta-909a3b/Company: https://www.huntress.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:How the Best CFOs Lead Without Being the CEO | Ken Stillwellhttps://youtu.be/O4cx9NBqQso—TIMESTAMPS:00:00:00 Preview and Intro00:01:01 Maria's Background00:03:09 People-First Team Building00:05:16 People, Process, Systems at Scale00:07:13 Removing Friction Outside Finance00:09:15 Data Transparency & Decision-Making00:11:06 Sponsors — Abacum | Brex | Metronome00:14:22 Forward-Deployed Data00:16:21 Centralized Data vs. Silos00:19:23 Finance as Data Steward00:21:08 Cost-to-Price Feedback Loop00:22:35 Curiosity Builds Credibility00:23:43 Sponsors — RightRev | Rillet | Tabs00:27:12 Trust First, Then Impact00:30:27 Celebrating Small Wins00:31:21 From Transactions to Insights00:33:00 CFO at the Revenue Table00:34:32 Educating the Org on Metrics00:36:21 Customer-Level Margin Reality00:37:13 Using Facts to Change Decisions00:38:27 Ownership Mindset in Growth Companies00:39:10 VC vs. PE vs. Public CFO Tradeoffs00:41:02 Operating Inside Constraints00:42:18 Finding Your Stage Fit00:44:17 Building a Personal Advisor Network00:46:43 Visibility and Women in Leadership00:47:44 Work–Life Integration, Not Balance00:48:45 Lightning Round: Biggest Mistake00:50:10 Advice to Younger Self00:51:36 Finance Tech Stack00:52:01 Craziest Expense Story00:52:44 Credits#RunTheNumbersPodcast #CFOLeadership #ScalingCompanies #DataDrivenDecisions #ExecutiveLeadership This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
In this episode of Run the Numbers, CJ sits down with Ken Stillwell, CFO and COO of Pegasystems, to explore the realities of leading from the second seat. Ken shares hard-earned lessons from guiding Pega through the shift from term licenses to ARR and ACV, including how to rework sales compensation without losing trust or momentum. They discuss the limits of KPI obsession, the importance of directional clarity over false precision, and why private equity often drives sharper execution than public markets—and how to apply that discipline while still playing the long game.—SPONSORS:Tabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cj—LINKS:Ken on LinkedIn: https://www.linkedin.com/in/ken-stillwell-83a499a/Pegasystems: https://www.pega.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:How Finance Becomes a GTM Partner, Not a Bottleneck | Chris Brubakerhttps://youtu.be/T2YjdoiJtFA—TIMESTAMPS:00:00:00 Preview and Intro00:02:57 Sponsors — Tabs | Abacum | Brex00:07:26 The Strategic Value of Being Number Two00:08:46 Earnings Calls, Messaging, and Real-Time Judgment00:10:41 Using Feedback to Sharpen Executive Communication00:11:38 CFOs as Storytellers & Message Repetition00:12:31 Managing Up: Reading the Room00:13:59 Learning the Hard Way: Misreading Dynamics00:15:18 Confidence, Aggression, and Early CFO Mistakes00:15:58 Sponsors — Metronome | RightRev | Rillet00:19:45 When to Email vs Pick Up the Phone00:22:48 Tailoring Communication to Different Functions00:23:23 Audience-Specific Messaging: “Why Me?”00:25:24 Values vs Behaviors in Leadership00:28:13 Why Big Changes Need Anchoring00:31:14 Moving Pega to the Cloud00:32:43 Rewiring Sales Comp for ARR & ACV00:34:56 Sales Credibility Breakdowns with Customers00:36:20 Economics vs Trust in Sales Teams00:37:48 Balancing Field Feedback with Company Goals00:39:17 De-Emphasizing New Logos to Fix the Sales Model00:41:12 The Danger of Over-Obsessing on KPIs00:42:51 Public vs Private: Incentives and Operating Discipline00:45:57 Why Companies Go Private: Motivation Over Patience00:47:29 The Shrinking Public Markets00:47:57 Private vs Public CFO Mindsets00:49:39 Meeting Investors Where They Are00:50:16 A Risky Decision That Paid Off: Going All-In on the Cloud00:51:29 Long-Ass Lightning Round00:53:24 Ken's Finance Tech Stack & Craziest Expense00:54:39 Credits#RunTheNumbersPodcast #CFOLeadership #ExecutiveCommunication #SalesStrategy #PublicVsPrivate This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
In this episode of the Jack Westin MCAT Podcast, Mike and Molly continue their MCAT brain anatomy series by tackling one of the most underrated topics on the exam: how the brain actually makes you move.If you've ever thought “why are there so many brain parts just for movement?” this episode is your roadmap.You'll learn:
In this episode of Run the Numbers, CJ sits down with Chris Brubaker, SVP of Finance at Postscript, who's helped build the finance function from the ground up. Chris shares how he partners with sales through deal desks, sets pricing guardrails, and makes sure finance helps close deals instead of slowing them down. They dig into his hands-on approach to automation using AI with limited engineering resources, how Postscript's metrics evolved as the company scaled, when to trust internal data over benchmarks, and where teams get tripped up. Plus, a private jet accounting story—because of course.—SPONSORS:Rillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.com—LINKS:Chris on LinkedIn: https://www.linkedin.com/in/wchrisbrubaker/Postscript: https://postscript.io/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:So You're Looking for a “Strategic” CFO? Bloomerang's Steve Isom on What That Really Meanshttps://youtu.be/cgHOtvG1CesThe IPO Playbook: Expert Advice from Lee Kirkpatrick, Twilio's Former CFOhttps://youtu.be/PTKAUD7PSWUThe CFO Case for Probabilistic Forecasting With AI | Bruno Annicqhttps://youtu.be/Dl8nDZPJMpE—TIMESTAMPS:00:00:00 Preview and Intro00:02:22 Sponsors — Rillet | Tabs | Abacum00:06:55 Interview Begins00:07:36 First Finance Hire and Early Scale at Postscript00:09:02 Usage-Based Margins, COGS, and the Twilio Parallel00:10:31 Partnering With Sales and Building Deal Desk00:13:16 Pricing Guardrails, Payback, and Deal Economics00:15:35 How Deal Desk Evolves Over Time00:16:01 Sponsors — Brex | Metronome | RightRev00:19:44 Making Finance a Deal-Closing Partner00:20:44 Automating Deal Desk With a Slack Bot00:23:48 How Technical Finance Leaders Need to Be00:25:17 Automating Without Engineering Help00:27:12 Why Human Touch Still Matters in SaaS00:27:53 Postscript's Finance Tech Stack00:28:30 ERP Migration and Month-End Efficiency00:29:42 The Reality of Continuous Close00:30:34 First Real AI Wins in Accounting00:31:18 Experimenting With AI Forecasting00:33:32 Metrics That Matter: Usage as a Leading Indicator00:35:49 How Metrics Evolve as the Company Scales00:37:41 Understanding the Product in a Usage-Based Model00:39:27 Micro-Seasonality and Forecasting Volatility00:42:21 How to Use Benchmarks Without Misusing Them00:43:50 Long-Ass Lightning Round: A Costly Modeling Mistake00:45:45 Advice to a Younger Finance Leader00:47:05 The Private Jet Accounting Story00:49:11 Credits#RunTheNumbersPodcast #FinanceLeadership #DealDesk #UsageBasedSaaS #AIinFinance This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
Thu, 15 Jan 2026 13:00:00 GMT http://relay.fm/cortex/175 http://relay.fm/cortex/175 Technology Connections – State of the Workflow 175 Myke Hurley Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. clean 3843 Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. This episode of Cortex is sponsored by: Sentry: Mobile crash reporting and app monitoring. New users get $100 in Sentry credits with code cortex26. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Guest Starring: Technology Connections Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Myke's 2026 Yearly Theme - Cortex - YouTube My 2026 Yearly Theme – The Enthusiast Technology Connections - YouTube Technology Connections | Patreon Teleprompters are clever, simple, and also pretty neat - Technology Connections - YouTube This goofy fridge has a really clever design. It's also kinda terrible. - Technology Connections - YouTube Video projectors used to be ridiculously cool - Technology Connections - YouTube Catalytic converters are simple, but getting them to work is not - Technology Connections - YouTube My car charger can boil water really fast - Technology Connections - YouTube Brown; color is weird - Technology Connections - YouTube Alec's Home Screen Tusky Pocket Casts Good Store - EcoGeek - Dishwasher Powder
Chad and Will start the new year off right by discussing their aspirations for 2026. Chad discusses this year's theme for the company of being bold and how having a clear vision keeps thoughtbot on track, the pair discuss how they plan to rise up to the challenge of being bold in their work, and Will seeks some advice on a project he's been looking to pursue. — Once you're done with this week's episode why not check out Chad's podcast recommendation of Cortex (https://www.relay.fm/cortex), a show that explores how creative people think about their work. You can find Chad all over social media as @cpytel. You can also connect with the duo via their LinkedIn pages - Chad (https://www.linkedin.com/in/cpytel/) - Will (https://www.linkedin.com/in/william-larry/) If you would like to support the show, head over to our GitHub page (https://github.com/sponsors/thoughtbot), or check out our website (https://podcast.thoughtbot.com). Got a question or comment about the show? Why not write to our hosts: hosts@giantrobots.fm This has been a thoughtbot (https://thoughtbot.com/) podcast. Stay up to date by following us on social media - LinkedIn (https://www.linkedin.com/company/150727/) - Mastodon (https://thoughtbot.social/@thoughtbot) - YouTube (https://www.youtube.com/thoughtbotvideo) - Bluesky (https://bsky.app/profile/thoughtbot.com) © 2026 thoughtbot, inc.
Thu, 15 Jan 2026 13:00:00 GMT http://relay.fm/cortex/175 http://relay.fm/cortex/175 Myke Hurley Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. clean 3843 Myke talks to Alec from Technology Connections about how he turns everyday tech into compelling videos, from topic selection and deep research to scripting, hands-on experimentation, filming, and editing entirely on his own. This episode of Cortex is sponsored by: Sentry: Mobile crash reporting and app monitoring. New users get $100 in Sentry credits with code cortex26. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Guest Starring: Technology Connections Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Myke's 2026 Yearly Theme - Cortex - YouTube My 2026 Yearly Theme – The Enthusiast Technology Connections - YouTube Technology Connections | Patreon Teleprompters are clever, simple, and also pretty neat - Technology Connections - YouTube This goofy fridge has a really clever design. It's also kinda terrible. - Technology Connections - YouTube Video projectors used to be ridiculously cool - Technology Connections - YouTube Catalytic converters are simple, but getting them to work is not - Technology Connections - YouTube My car charger can boil water really fast - Technology Connections - YouTube Brown; color is weird - Technology Connections - YouTube Alec's Home Screen Tusky Pocket Casts Good Store - EcoGeek - Dishwasher Powder
In this episode of Run the Numbers, CJ sits down with Bruno Annicq, CFO of Wellhub (formerly Gympass), to unpack a practical finance playbook built around cash discipline, sustainable growth, and simplicity. Bruno explains how he rebuilt forecasting using an AI-driven, probabilistic ensemble model, moving teams beyond single-scenario planning. They also dig into his EMPOWER planning framework, usable OKRs, and why tighter alignment between finance, HR, and wellbeing is becoming a durable lever for long-term performance.—SPONSORS:RightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.com—LINKS:Bruno on LinkedIn: https://www.linkedin.com/in/bannicq/Wellhub: https://wellhub.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:“Run Toward a Tough Market” — Developing the Hard and Soft Skills To Be a Great Finance Leaderhttps://youtu.be/iNHbkcG7YEo—TIMESTAMPS:00:00:00 Preview and Intro00:02:19 Sponsors — RightRev, Rillet, Tabs00:06:43 Accidental CFO Origin Story00:07:34 Consulting to Operations Pivot00:08:12 Why Finance Clicked for Bruno00:09:28 McKinsey Prioritization in Real World00:10:02 Eisenhower Matrix and Prioritization00:11:08 Investing in Non-Urgent Work00:13:30 Lessons From AOL Reinvention00:16:10 Sponsors — Abacum, Brex, Metronome00:20:01 Career Growth Through Hard Problems00:20:52 Broadening Skills Through Change00:23:12 Five Core Finance Principles00:24:02 Cash Is King00:25:14 Driving Sustainable Growth00:26:01 No Surprises and Forecasting00:26:07 Finance as Business Enabler00:27:22 Less Is More Philosophy00:28:47 Hardest Principle: Less Is More00:29:46 Deterministic vs Probabilistic Forecasting00:31:11 Marketplace Volatility and Forecast Error00:32:10 Ensemble Models Explained00:33:37 Forecast Accuracy Gains00:34:53 Building Models In-House00:36:46 Why Explainability Matters00:37:48 Empower Framework Introduction00:47:47 Urgency, Compounding, Long-Term Thinking00:48:10 Advice to Younger Self00:50:06 Finance Stack and Expense Stories00:52:51 Credits#RunTheNumbersPodcast #CFO #FinanceLeadership #Forecasting #AIinFinance This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
In this episode of Run the Numbers, CJ sits down with Jason Kong, General Partner at Base10 Ventures, to unpack the firm's focus on “automation for the real economy” — software built for industries most tech investors overlook, but the world depends on. Jason breaks down what makes Series B investing uniquely hard, how he evaluates back-office and vertical SaaS opportunities, and where markets tip from niche to overcrowded. They also discuss Base10's decision to donate 50% of profits to fund scholarships, plus a lightning round spanning fantasy football, shorting SaaS in 2022, and a venture take that might spark debate.—SPONSORS:Metronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metrics—LINKS:Jason on LinkedIn: https://www.linkedin.com/in/jasonykong/Base10 Partners: https://base10.vc/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:Scaling to $1B+ Revenue: From ServiceNow to Samsara | Dominic Phillipshttps://youtu.be/vBY6WZBMljw—TIMESTAMPS:00:00:00 Preview and Intro00:02:20 Sponsors — Metronome, RightRev, Rillet00:06:02 Base10 Background00:06:41 Automation for the Real Economy00:09:27 Vertical vs. Horizontal Software00:10:38 Cash Flow and Durability00:11:19 Product-Market Fit and ROI00:12:56 Growth Limits Selling to Tech00:13:19 The Size of the Real Economy00:14:16 Sponsors — Tabs, Abacum, Brex00:18:50 Base10's Giving Model00:20:30 Access, Education, and Tech00:21:53 Purpose and Founder Alignment00:22:51 Radical Transparency00:23:56 Portfolio Focus and Strategy00:24:05 Investing Ahead of Consensus00:26:29 ERP Adjacency as Alpha00:28:58 Lessons From Hedge Funds00:32:29 Public Markets Reality00:34:05 Public vs. Private Investing00:34:48 The Series B Sweet Spot00:36:49 A Bifurcated Series B Market00:38:56 Fast Series Bs and 2021 Vibes00:42:16 What Series B Looks Like Now00:44:36 Back Office Automation00:46:02 ERP-Centric Workflows00:48:33 Long-Ass Lightning Round00:49:36 Shorting SaaS in 202200:50:16 Fantasy Football and Investing00:52:57 Career Advice That Surprises00:55:03 A Contrarian Venture Take00:56:22 Credits#RunTheNumbersPodcast #SeriesB #RealEconomy #VerticalSaaS #BackOfficeAutomation This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
In this episode of Run the Numbers, CJ sits down with Dominic Phillips, CFO of Samsara, to unpack what it takes to scale a capital-intensive SaaS business from startup to public company in under a decade. Dominic reflects on his six-plus years at Samsara through hypergrowth, COVID disruption, supply chain constraints, a down-round survival raise, and an IPO at the very end of the 2021 tech window. Drawing on his earlier career at ServiceNow under Mike Scarpelli, he shares how experience across FP&A, IR, corp dev, and treasury shaped his approach to capital allocation, investor education, and analyst management. The conversation dives into asset-based pricing, selling into non-discretionary operations budgets, balancing hardware and software economics, and building credibility with a broad analyst base while scaling past $1B in ARR.—SPONSORS:Brex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/runAbacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.ai—LINKS:Dominic on LinkedIn: https://www.linkedin.com/in/dominicphillips/Company: https://www.samsara.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:“Steal Your Boss's Job”: Calendly CFO John McCauley on Leadership, Ownership & Growthhttps://youtu.be/VRpTNDIfzPYFrom SMB to Enterprise: The CFO Scaling Playbook With Andrew Casey | Mostly Classicshttps://youtu.be/kMuJ6gAuEpgDriving revenue without selling | Greg Henry of 1Passwordhttps://youtu.be/f5FsNoG8A3E—TIMESTAMPS:00:00:00 Preview & Intro00:02:40 Sponsors — Brex | Metronome | RightRev00:06:18 Interview Begins00:06:46 Dominic's Early Career00:08:47 From ServiceNow to CFO00:09:47 Joining Samsara00:10:54 COVID, Burn, and a Down Round00:12:40 IPO Messaging and Investor Education00:15:50 Sponsors — Rillet | Tabs | Abacum00:20:27 Hardware + Software Story00:21:29 What Samsara Does00:22:30 Data, AI, and ROI00:23:23 Horizontal Platform and Verticals00:24:27 Growth Drivers at Scale00:26:09 Selling Into Operations00:28:19 Change Management in Legacy Orgs00:29:46 Non-Discretionary Budgets00:33:02 Storytelling Lessons from Scarpelli00:36:14 Managing Analysts00:39:23 Earnings Timing Strategy00:41:06 Metrics and Investor Trust00:42:38 Investor Communication Channels00:44:22 Investor Days and Long-Term Vision00:45:37 Annual Planning Maturity00:48:24 Forecast Accuracy and Cadence00:49:28 The 1000-Day Strategy00:50:40 Top-Line and Margin Targets00:51:59 Capital Allocation by Function00:54:46 Becoming a CFO00:58:21 Lightning Round and a CFO Mistake01:02:41 End Credits#RunTheNumbersPodcast #CFO #ScalingCompanies #B2BSaaS #PublicMarkets This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
In this episode of Run the Numbers, CJ Gustafson sits down with Gordon Coyle, a 40-year commercial insurance veteran, to demystify one of the most anxiety-inducing topics for founders and CFOs: business insurance. Drawing on decades of experience with startups, scaleups, and regulated industries, Gordon breaks down what leaders need to know about D&O, E&O, cyber, and general liability, why investor pressure is rising, and where “cheap and easy” online policies fail when real risk hits. Through real-world examples, they explore how claims arise, how defense costs erode limits, why cyber insurance is as much about response as reimbursement, and how to balance budget, risk tolerance, and peer benchmarks—treating insurance as a critical layer of protection, not a box-checking exercise.—SPONSORS:Abacum is a modern FP&A platform built by former CFOs to replace slow, consultant-heavy planning tools. With self-service integrations and AI-powered workflows for forecasting, variance analysis, and scenario modeling, Abacum helps finance teams scale without becoming software admins. Trusted by teams at Strava, Replit, and JG Wentworth—learn more at https://www.abacum.aiBrex is an intelligent finance platform that combines corporate cards, built-in expense management, and AI agents to eliminate manual finance work. By automating expense reviews and reconciliations, Brex gives CFOs more time for the high-impact work that drives growth. Join 35,000+ companies like Anthropic, Coinbase, and DoorDash at https://www.brex.com/metricsMetronome is real-time billing built for modern software companies. Metronome turns raw usage events into accurate invoices, gives customers bills they actually understand, and keeps finance, product, and engineering perfectly in sync. That's why category-defining companies like OpenAI and Anthropic trust Metronome to power usage-based pricing and enterprise contracts at scale. Focus on your product — not your billing. Learn more and get started at https://www.metronome.comRightRev is an automated revenue recognition platform built for modern pricing models like usage-based pricing, bundles, and mid-cycle upgrades. RightRev lets companies scale monetization without slowing down close or compliance. For RevRec that keeps growth moving, visit https://www.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to close faster without fighting legacy systems. Designed to support complex revenue recognition, multi-entity operations, and real-time reporting, Rillet helps teams achieve a true zero-day close—with some customers closing in hours, not days. If you're scaling on an ERP that wasn't built in the 90s, book a demo at https://www.rillet.com/cjTabs is an AI-native revenue platform that unifies billing, collections, and revenue recognition for companies running usage-based or complex contracts. By bringing together ERP, CRM, and real product usage data into a single system of record, Tabs eliminates manual reconciliations and speeds up close and cash collection. Companies like Cortex, Statsig, and Cursor trust Tabs to scale revenue efficiently. Learn more at https://www.tabs.com/run—LINKS:Gordon on LinkedIn: https://www.linkedin.com/in/gordoncoyle/The Coyle Group: https://thecoylegroup.com/CJ on LinkedIn: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—RELATED EPISODES:The Coyle Group - Business Insurancehttps://www.youtube.com/@TheCoyleGroupNY—TIMESTAMPS:00:00:00 Preview and Intro00:01:53 Sponsors — Abacum | Brex | Metronome00:05:39 Interview Begins with Gordon Coyle00:06:23 Gordon Coyle & The Coyle Group00:07:21 Explaining Insurance on YouTube00:08:40 Turning Education into Inbound Leads00:09:40 Content as a Pull Strategy00:10:53 Insurance Complexity for Tech Founders00:13:28 Why Investors Require D&O Insurance00:14:09 What D&O Covers and Why It Matters00:15:50 Sponsors — RightRev | Rillet | Tabs00:20:19 Who D&O Covers and Rising Investor Pressure00:22:37 D&O Limits and Cost Tradeoffs00:23:21 Panic Calls and Late D&O Purchases00:24:39 How Defense Costs Erode Coverage00:25:31 Common D&O Claims and Employment Risk00:27:08 D&O vs E&O Explained00:29:12 Cyber Insurance and Social Engineering00:31:59 AI's Impact on Cyber Risk00:33:50 Real-World Ransomware Stories00:34:17 Cyber Insurance as Money and Response00:35:29 Business Email Compromise Scams00:39:43 Why Tech Still Needs General Liability00:41:16 What a BOP Covers00:42:32 Convenience vs Proper Coverage00:44:29 Surprising General Liability Claims00:46:45 Insurance Costs for Startups00:47:36 Higher Costs in High-Risk Industries00:48:26 Balancing Budget, Risk, and Coverage00:50:39 PEOs, Workers' Comp, and EPLI00:54:39 Choosing the Right Insurance Partner00:56:42 End Credits#RunTheNumbersPodcast #StartupFinance #BusinessInsurance #RiskManagement #CyberRisk This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cjgustafson.substack.com
Dan Nathan and Guy Adami host Steph Guild, Chief Investment Officer at Robinhood. Steph discusses her 2026 market outlook, reflecting on tech sector growth, AI developments, and S&P 500 predictions. She emphasizes her cautious approach for the coming year, focusing on diversification and value investing. After the break, Steve Quirk, Chief Brokerage Officer at Robinhood joins the pod. Steve talks about Robinhood's latest offerings, including prediction markets and event contracts, highlighting their rapid growth and retail investor interest. The episode also explores new AI tools like Cortex for customer portfolio management and Robinhood's new social platform aimed at fostering community and idea sharing among investors. —FOLLOW USYouTube: @RiskReversalMediaInstagram: @riskreversalmediaTwitter: @RiskReversalLinkedIn: RiskReversal Media
¿Puede existir la mente cuando el cerebro apenas está ahí? En este episodio de Hemispherics exploramos casos clínicos extremos —hidrocefalias masivas, hemisferectomías, microcefalia— y estados límite de conciencia como la lucidez terminal, la conciencia bajo anestesia o las experiencias cercanas a la muerte. Historias reales, bien documentadas, que desafían la idea simplista de que “la mente es solo el cerebro”. No para abrazar lo místico, sino para ampliar el marco: plasticidad extrema, redes alternativas, conciencia distribuida y los límites reales de lo que hoy sabemos. Un viaje a los bordes de la neurociencia, donde las respuestas no son claras… pero las preguntas son fascinantes. Referencias del episodio: 1. Asaridou, S. S., Demir-Lira, Ö. E., Goldin-Meadow, S., Levine, S. C., & Small, S. L. (2020). Language development and brain reorganization in a child born without the left hemisphere. Cortex; a journal devoted to the study of the nervous system and behavior, 127, 290–312. https://doi.org/10.1016/j.cortex.2020.02.006 (https://pubmed.ncbi.nlm.nih.gov/32259667/). 2. Feuillet, L., Dufour, H., & Pelletier, J. (2007). Brain of a white-collar worker. Lancet (London, England), 370(9583), 262. https://doi.org/10.1016/S0140-6736(07)61127-1 (https://pubmed.ncbi.nlm.nih.gov/17658396/). 3. Green, A. J., Yates, J. R., Taylor, A. M., Biggs, P., McGuire, G. M., McConville, C. M., Billing, C. J., & Barnes, N. D. (1995). Severe microcephaly with normal intellectual development: the Nijmegen breakage syndrome. Archives of disease in childhood, 73(5), 431–434. https://doi.org/10.1136/adc.73.5.431 (https://pubmed.ncbi.nlm.nih.gov/8554361/). 4. Kofman, K., & Levin, M. (2025). Cases of unconventional information flow across the mind-body interface. Mind and Matter, 23(1), Article 13. https://doi.org/10.5376/mm2025.13 (https://www.ingentaconnect.com/content/imp/mm/2025/00000023/00000001/art00003). 5. Lewin R. (1980). Is your brain really necessary?. Science (New York, N.Y.), 210(4475), 1232–1234. https://doi.org/10.1126/science.7434023 (https://pubmed.ncbi.nlm.nih.gov/7434023/). 6. Merker B. (2007). Consciousness without a cerebral cortex: a challenge for neuroscience and medicine. The Behavioral and brain sciences, 30(1), 63–134. https://doi.org/10.1017/S0140525X07000891 (https://pubmed.ncbi.nlm.nih.gov/17475053/). 7. Parnia, S., Spearpoint, K., de Vos, G., Fenwick, P., Goldberg, D., Yang, J., Zhu, J., Baker, K., Killingback, H., McLean, P., Wood, M., Zafari, A. M., Dickert, N., Beisteiner, R., Sterz, F., Berger, M., Warlow, C., Bullock, S., Lovett, S., McPara, R. M., … Schoenfeld, E. R. (2014). AWARE-AWAreness during REsuscitation-a prospective study. Resuscitation, 85(12), 1799–1805. https://doi.org/10.1016/j.resuscitation.2014.09.004 (https://pubmed.ncbi.nlm.nih.gov/25301715/). 8. Parnia, S., Keshavarz Shirazi, T., Patel, J., Tran, L., Sinha, N., O'Neill, C., Roellke, E., Mengotto, A., Findlay, S., McBrine, M., Spiegel, R., Tarpey, T., Huppert, E., Jaffe, I., Gonzales, A. M., Xu, J., Koopman, E., Perkins, G. D., Vuylsteke, A., Bloom, B. M., … Deakin, C. D. (2023). AWAreness during REsuscitation - II: A multi-center study of consciousness and awareness in cardiac arrest. Resuscitation, 191, 109903. https://doi.org/10.1016/j.resuscitation.2023.109903 (https://pubmed.ncbi.nlm.nih.gov/37423492/). 9. Ross, J. P., Post, S. G., & Scheinfeld, L. (2024). Lucidity in the Deeply Forgetful: A Scoping Review. Journal of Alzheimer's disease : JAD, 98(1), 3–11. https://doi.org/10.3233/JAD-231396 (https://pmc.ncbi.nlm.nih.gov/articles/PMC10977389/). 10. Sandhu, K., & Dash, H. (2009). Awareness during anaesthesia. Indian journal of anaesthesia, 53(2), 148–157 (https://pubmed.ncbi.nlm.nih.gov/20640115/). 11. Teresi, J. A., Ramirez, M., Ellis, J., Tan, A., Capezuti, E., Silver, S., Boratgis, G., Eimicke, J. P., Gonzalez-Lopez, P., Devanand, D. P., & Luchsinger, J. A. (2023). Reports About Paradoxical Lucidity from Health Care Professionals: A Pilot Study. Journal of gerontological nursing, 49(1), 18–26. https://doi.org/10.3928/00989134-20221206-03 (https://pmc.ncbi.nlm.nih.gov/articles/PMC11100277/). 12. Timmermann, C., Roseman, L., Williams, L., Erritzoe, D., Martial, C., Cassol, H., Laureys, S., Nutt, D., & Carhart-Harris, R. (2018). DMT Models the Near-Death Experience. Frontiers in psychology, 9, 1424. https://doi.org/10.3389/fpsyg.2018.01424 (https://pubmed.ncbi.nlm.nih.gov/30174629/).
Episode summaryWhat happens when you close your eyes and try to “see” something in your mind? For some people it's a full-colour mental movie. For others it's hazy, fleeting or completely blank. In this episode, Dr Sabina Brennan explores the neuroscience of mental imagery, including eigengrau (that grainy ‘intrinsic grey' most people notice in darkness), the spectrum from aphantasia to hyperphantasia and why visualisation is less about forcing pictures and more about learning how your brain constructs experience.In this episode, Sabina coversWhy “seeing nothing” when you visualise doesn't mean you're bad at imaginationEigengrau – what that smoky grey tells us about baseline visual activityAphantasia and hyperphantasia – two ends of the imagery vividness spectrumMental imagery in brain terms: top-down simulation meeting bottom-up perceptionWhy worry is often a “mental movie” and how imagery can amplify emotionHow imagery is used in sport, performance, rehab and therapyTools in Three: how to work with imagery whatever your baselineKey takeawaysImagery varies hugely between people and it's normal.Visualisation isn't just visual – sound, touch, movement, emotion and language can carry imagination too.The goal isn't perfect pictures, it's intentional rehearsal that shapes attention, expectation and behaviour.The most effective visualisation tends to be process-focused, not just outcome-focused.Tools in Three1. Know your baseline – stop forcing a cinema screen. Work with your strongest channel (words, sensation, sound, movement).2. Build a multisensory practice – start with a real object, then recreate it with eyes closed. Add texture, temperature, weight, sound. Pair calming imagery with slow breathing.3. Apply imagery intentionally and aim for process – rehearse the steps, the likely wobble moments and how you'll recover, not just the “trophy scene”.Memorable lines (pull quotes)“Imagination isn't about pictures. It's about possibility.”“Worry is often imagery too – the brain running mental movies of what might go wrong.”“Aphantasia is not an imagination failure. It is a different format for thinking.”References (as cited in the episode)Zeman A, Dewar M, Della Sala S. Lives without imagery – Congenital aphantasia. Cortex. 2015.S6E6 - Visualisation beefed up …Pearson J. The human imagination: the cognitive neuroscience of visual mental imagery. Nat Rev Neurosci. 2019.Milton F, et al. Aphantasia and hyperphantasia: extreme differences in visual imagery vividness. Cortex. 2021.Tagsvisualisation, mental imagery, aphantasia, hyperphantasia, eigengrau, neuroscience of imagination, memory, anxiety, sport psychology, mental rehearsal, guided imagery, manifesting, brain predictionSupport this show http://supporter.acast.com/superbrain. Hosted on Acast. See acast.com/privacy for more information.
Apple and Google issue emergency updates to patch zero-days. Google links five additional Chinese state-backed hacking groups to “React2Shell.” France's Ministry of the Interior was hit by a cyberattack. Atlassian patches roughly 30 third-party vulnerabilities. Microsoft says its December 2025 Patch Tuesday updates are breaking Message Queuing. Researchers uncovered a massive exposed database with nearly 4.3 billion professional records openly accessible online. Britain's new MI6 chief warns of an “aggressive, expansionist, and revisionist” Russia. Monday Business Brief. On today's Threat Vector, Michael Heller from Unit 42 chats with security leaders Greg Conti and Tom Cross to unpack the hacker mindset and the idea of “dark capabilities”. A cyber holiday gift guide for the rest of us. Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. Threat Vector Segment In this segment of Threat Vector, host Michael Heller, Managing Editor for Cortex and Unit 42 and Executive Producer of the podcast, sits down with long-time security leaders Greg Conti and Tom Cross to unpack the hacker mindset and the idea of “dark capabilities” inside modern technology companies. You can listen to their full discussion here. Be sure to catch new episodes of Threat Vector by Palo Alto Networks every Thursday on your favorite podcast app. Selected Reading Apple, Google forced to issue emergency 0-day patches (The Register) Google links more Chinese hacking groups to React2Shell attacks (Bleeping Computer) French Interior Ministry confirms cyberattack on email servers (Bleeping Computer) Atlassian Patches Critical Apache Tika Flaw (SecurityWeek) Microsoft: December security updates cause Message Queuing failures (Bleeping Computer) 16TB of MongoDB Database Exposes 4.3 Billion Lead Gen Records (Hackread) MI6 chief warns 'front line is everywhere' and signals intent to pressure Putin (The Record) Saviynt raises $700 million in Series B growth equity financing. (The CyberWire Business Brief) Last-minute cybersecurity and privacy gifts your friends and family won't hate (This Week In Security) Share your feedback. What do you think about CyberWire Daily? Please take a few minutes to share your thoughts with us by completing our brief listener survey. Thank you for helping us continue to improve our show. Want to hear your company in the show? N2K CyberWire helps you reach the industry's most influential leaders and operators, while building visibility, authority, and connectivity across the cybersecurity community. Learn more at sponsor.thecyberwire.com. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices
Snowflake VP of Product Management Chris Child joins Tristan Handy to unpack Snowflake's AI roadmap and what it means for data teams. They discuss the evolution from Snowpark to Cortex and Snowflake Intelligence, how to govern agents with row- and column-level controls, and why Snowflake is investing in Apache Iceberg and the Open Semantic Interchange initiative (dbt Labs recently open sourced MetricsFlow, the technology that powers the dbt Semantic Layer, to align with the goals of OSI). Chris also shares a vision for the next five years of data engineering: fewer bespoke pipelines, more standardization and semantics, and a bigger focus on business context and data products. For full show notes and to read 6+ years of back issues of the podcast's companion newsletter, head to https://roundup.getdbt.com. The Analytics Engineering Podcast is sponsored by dbt Labs.
Fri, 12 Dec 2025 17:00:00 GMT http://relay.fm/cortex/174 http://relay.fm/cortex/174 Marques Brownlee (MKBHD) – State of the Workflow 174 Myke Hurley Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. clean 4875 Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. This episode of Cortex is sponsored by: Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Guest Starring: Marques Brownlee Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback MKBHD.com MKBHD - Marques Brownlee - YouTube The Studio - YouTube WVFRM Podcast - YouTube Auto Focus - YouTube TickTick OnePlus 15 Review: This is Not Normal! - MKBHD - YouTube Do Bad Reviews Kill Companies? - MKBHD - YouTube Wait... Smart Glasses are Suddenly Good? - MKBHD - YouTube Marques' Home Screen Superhuman Arc Dia MKBHD Store
Fri, 12 Dec 2025 17:00:00 GMT http://relay.fm/cortex/174 http://relay.fm/cortex/174 Myke Hurley Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. clean 4875 Myke talks to Marques Brownlee about how he builds his reviews, from shaping a product narrative and writing scripts to collaborating with his team, deciding what becomes a video, and managing the pressure of creating at massive scale. This episode of Cortex is sponsored by: Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Guest Starring: Marques Brownlee Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback MKBHD.com MKBHD - Marques Brownlee - YouTube The Studio - YouTube WVFRM Podcast - YouTube Auto Focus - YouTube TickTick OnePlus 15 Review: This is Not Normal! - MKBHD - YouTube Do Bad Reviews Kill Companies? - MKBHD - YouTube Wait... Smart Glasses are Suddenly Good? - MKBHD - YouTube Marques' Home Screen Superhuman Arc Dia MKBHD Store
Pour cette fin d'année, Contre-addictions vous propose de découvrir ou redécouvrir des épisodes qui ont marqué les premières saisons du podcast.
Day 2 of F3: Future of Freight Festival brings the energy, the insights, and the triple-threat lineup. Host Malcolm Harris goes live from downtown Chattanooga to dive into the evolving world of freight tech, AI, payments, and innovation—straight from the leaders building the future. Guest #1 — Garrett Wolfe, EVP of Market Strategy, TriumphGarrett breaks down Triumph's purpose-built, verified freight transaction network, how their data and payments ecosystem powers trust, fraud prevention, and smarter decision-making, and why AI is a tool—not a buzzword—to be deployed when it improves customer outcomes.Guest #2 - Daniel Lucas, VP of Innovation & Business Strategy, UFSDaniel brings a decade-plus of logistics and tech experience to talk about AI as a freight copilot—and why companies must standardize their processes before plugging AI into their workflow. Guest #3 — Danielle Villegas, Chief Product Officer, PCSPCS flips the script by putting midsize carriers first. Danielle shares how their embedded AI engine, Cortex, is driving efficiency, accuracy, and profitability—plus, her team wins Best in Show live on the air. Watch on YouTube Visit our sponsor Subscribe to the WTT newsletter Apple Podcasts Spotify More FreightWaves Podcasts #WHATTHETRUCK #FreightNews #supplychain Learn more about your ad choices. Visit megaphone.fm/adchoices
Day 2 of F3: Future of Freight Festival brings the energy, the insights, and the triple-threat lineup. Host Malcolm Harris goes live from downtown Chattanooga to dive into the evolving world of freight tech, AI, payments, and innovation—straight from the leaders building the future. Guest #1 — Garrett Wolfe, EVP of Market Strategy, TriumphGarrett breaks down Triumph's purpose-built, verified freight transaction network, how their data and payments ecosystem powers trust, fraud prevention, and smarter decision-making, and why AI is a tool—not a buzzword—to be deployed when it improves customer outcomes.Guest #2 - Daniel Lucas, VP of Innovation & Business Strategy, UFSDaniel brings a decade-plus of logistics and tech experience to talk about AI as a freight copilot—and why companies must standardize their processes before plugging AI into their workflow. Guest #3 — Danielle Villegas, Chief Product Officer, PCSPCS flips the script by putting midsize carriers first. Danielle shares how their embedded AI engine, Cortex, is driving efficiency, accuracy, and profitability—plus, her team wins Best in Show live on the air. Watch on YouTube Visit our sponsor Subscribe to the WTT newsletter Apple Podcasts Spotify More FreightWaves Podcasts #WHATTHETRUCK #FreightNews #supplychain Learn more about your ad choices. Visit megaphone.fm/adchoices
Na semana que marca dois anos da famigerada hérnias tour, a @katbarcelos chega no episódio de hoje com a explicação do sumiço dela, duas dicas valiosas e um quadro totalmente novo na timeline do Vortex!Use o nosso link e garanta descontos absurdos de até 50% na sua matrícula na Black November da Alura: https://alura.com.br/vortex Host: Katiucha Barcelos. Instagram: @katbarcelos | Twitter/X: @katiuchaInstagram: @feedvortexBluesky: @feedvortex.bsky.sociaTwitter: @feedvortexTiktok: @feedvortexReddit: r/feedvortexGrupo paralelo não-oficial do Vortex no telegram: https://t.me/+BHlkG92BfPU5ZjdhEsse grupo é dos ouvintes, para os ouvintes e pelos ouvintes. Não temos qualquer afiliação oficial ou responsabilidade por QUALQUER COISA falada neste grupoLink do post do episódio nas redes sociais:InstagramTwitterLinks comentados no episódio:Linda Linda Linda (Filme) - 2005 O post icônico Kat Maromba Livro "The Great Good Place" Clipe comemorativo de Haikyuu: 20 anos de formação da banda Burnout SyndromesMAD do mangá de Haikyuu Produção: Thyara Castro, Bruno Azevedo e Aparecido SantosEdição: Joel SukeIlustração da capa: Brann Sousa
Tue, 11 Nov 2025 13:15:00 GMT http://relay.fm/cortex/173 http://relay.fm/cortex/173 Hank Green – State of the Workflow 173 Myke Hurley Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. clean 4839 Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Stuff: Organize your life and achieve your goals. Get 50% off your first year of Extra Stuff with code STUFF. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Guest Starring: Hank Green Links and Show Notes: Submit Feedback
Tue, 11 Nov 2025 13:15:00 GMT http://relay.fm/cortex/173 http://relay.fm/cortex/173 Myke Hurley Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. clean 4839 Myke talks to Hank Green about how he manages an impossibly full creative life — from YouTube and Crash Course to books, businesses, and Good.Store — using simple tools, structured weeks, selective meetings, delegation, and a constant flow of new ideas. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Stuff: Organize your life and achieve your goals. Get 50% off your first year of Extra Stuff with code STUFF. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Guest Starring: Hank Green Links and Show Notes: Submit Feedback
In this episode, we review the high-yield topic of Adrenal Cortex and Medulla from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode of The Evolving Leader, co-hosts Jean Gomes and Scott Allender talk to neurologist and author Adam Zeman about his latest book The Shape of Things Unseen. Together they explore how imagination helps us step outside the here and now, recall the past, and anticipate the future, and why this ability matters more than ever in a world shaped by automation and accelerating change.Adam takes us inside the science of the mind's eye, from aphantasia (the inability to visualise) to hyperphantasia (imagery as vivid as reality), and unpacks what these differences reveal about creativity, culture and leadership. This conversation offers practical insights for leaders on cultivating imagination within organisations, the role of daydreaming in innovation, and how to create environments where ideas can flourish.Further materials from Adam Zeman:Zeman, A. (2025). The Shape of Things Unseen: A New Science of Imagination. Bloomsbury.Zeman, A., Milton, F., Della Sala, S. (2024). “Aphantasia and Hyperphantasia: Exploring imagery vividness extremes.” Cortex, 170, 1–14.Zeman, A. (2024). “Aphantasia: The science of visual imagery absence.” Trends in Cognitive Sciences, 28(3), 189–200. Other reading from Jean Gomes and Scott Allender:Leading In A Non-Linear World (J Gomes, 2023)The Enneagram of Emotional Intelligence (S Allender, 2023)Social:Instagram @evolvingleaderLinkedIn The Evolving Leader PodcastTwitter @Evolving_LeaderBluesky @evolvingleader.bsky.socialYouTube @evolvingleader The Evolving Leader is researched, written and presented by Jean Gomes and Scott Allender with production by Phil Kerby. It is an Outside production.Send a message to The Evolving Leader team
Crash Bandicoot is getting an animated series at Netflix with WildBrain partnering on production. Expect a bright, slapstick tone that leans into classic Crash chaos, with Cortex likely in the villain seat and a deep bench of side characters. We talk why Netflix is a strong home for game adaptations, how this compares to earlier attempts, and what details still need to be announced like casting and a showrunner. This is a nostalgia win for longtime players and an easy on-ramp for kids who are meeting Crash for the first time. 00:00 Crash Bandicoot series announced for Netflix, WildBrain on board00:12 Tone expectations: silly, slapstick, colorful, classic Crash energy00:17 Appeal for families and longtime players00:29 Earlier TV attempt that stalled and why Netflix is a better fit00:34 Track record of game adaptations on Netflix00:45 What we are watching next: casting and showrunner newsNetflix is developing a Crash Bandicoot animated series with WildBrain, aiming for high-energy slapstick and bold visuals.The show targets a wide audience, pairing kid-friendly fun with nostalgia for fans who grew up with the games.A prior version was explored elsewhere but did not move forward, which makes Netflix's infrastructure and history with game adaptations a promising sign.Big open questions remain, including voice cast, showrunner, and release timing.If Netflix taps into Cortex, Crash, and the extended roster of allies and foes, the series has room for episodic humor and fan-service deep cuts.“Crash Bandicoot is coming to Netflix… it should be silly slapstick, very colorful.”“Kids are going to dig it and the parents are going to be like, oh yeah, I played that game.”“We've seen Netflix take video game properties and turn them into really successful animations.”“The next thing we're looking for is casting and who's going to be the showrunner.”“I'm always down for nostalgia.”Enjoy the episode? Follow and subscribe to Geek Freaks, leave a quick rating and review, and share the show with a friend using #GeekFreaks. It helps more fans find the conversation.All news discussed on our shows comes from GeekFreaksPodcast.comFacebook: https://www.facebook.com/thegeekfreakspodcastThreads: https://www.threads.net/@geekfreakspodcastTwitter: https://twitter.com/geekfreakspodInstagram: https://www.instagram.com/geekfreakspodcast/Patreon: https://www.patreon.com/GeekFreakspodcastFrank on Instagram: @franklourence79What do you want most from a Crash Bandicoot series on Netflix, and who would you cast as Crash or Cortex? Send your thoughts for a chance to be featured in a future episode.Crash Bandicoot, Netflix, WildBrain, Video Game Adaptations, Dr. Neo Cortex, Animation, Nostalgia, Geek Freaks, Arcane, Cyberpunk Edgerunners, Tomb Raider, Splinter CellTimestamps and TopicsKey TakeawaysQuotesCall to ActionLinks and ResourcesFollow UsListener QuestionsApple Podcast Tags
Tue, 21 Oct 2025 11:15:00 GMT http://relay.fm/cortex/172 http://relay.fm/cortex/172 David Pierce – State of the Workflow 172 Myke Hurley Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. clean 5352 Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Incogni: Take your personal data back with Incogni! Use code CORTEX with this link and get 60% off an annual plan. Guest Starring: David Pierce Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Tue, 21 Oct 2025 11:15:00 GMT http://relay.fm/cortex/172 http://relay.fm/cortex/172 Myke Hurley Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. clean 5352 Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Incogni: Take your personal data back with Incogni! Use code CORTEX with this link and get 60% off an annual plan. Guest Starring: David Pierce Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
What if AI could actually remember like humans do?Biswaroop Bhattacharjee joins Demetrios Brinkmann to challenge how we think about memory in AI. From building Cortex—a system inspired by human cognition—to exploring whether AI should forget, this conversation questions the limits of agentic memory and how far we should go in mimicking the mind.Guest speaker: Biswaroop Bhattacharjee - Senior ML Engineer at Prem AIHost :Demetrios Brinkmann - Founder of MLOps Community~~~~~~~~ ✌️Connect With Us ✌️ ~~~~~~~Catch all episodes, blogs, newsletters, and more: https://go.mlops.community/TYExploreJoin our Slack community [https://go.mlops.community/slack]Follow us on X/Twitter [@mlopscommunity](https://x.com/mlopscommunity) or [LinkedIn](https://go.mlops.community/linkedin)] Sign up for the next meetup: [https://go.mlops.community/register]MLOps Swag/Merch: [https://shop.mlops.community/]#podcast #aiinfrastructure #aiagents #memory
THE TIM JONES AND CHRIS ARPS SHOW 0:00 SEG 1 Hostage says he was treated better after Trump won the election | St. Louis City Sheriff Alfred Montgomery is going to jail to wait for trial | Charlie Kirk’s widow accepts The Medal of Freedom on behalf of Charlie 18:03 SEG 2 DAVID STOKES, Director of Municipal Policy at the Show-Me Institute | TOPIC: Cortex Eminent Domain Extension: St. Louis lawmakers are moving to extend the Cortex innovation district’s eminent domain powers for another five years. Supporters say it’s key to continued growth, while critics question whether the authority is applied fairly across the city. | Cottleville Development Pause: Cottleville is considering a six-month moratorium on certain new housing projects to manage rapid growth. Supporters want time to update zoning rules, while builders warn it could drive development elsewhere. | University City Apartment Plan Faces Pushback: A proposal to build apartments on a rare forested plot faces resistance after a city panel said it could worsen flooding along the River Des Peres. showmeinstitute.org/author/david-stokesx.com/DavidCStokes 35:28 SEG 3 Chris’ Corner is about the guy who burnt down PA’s gov mansion pleading guilty | Trump hates his TIME Magazine cover | Trump on media coverage of Hamas deal | Trafalgar polling https://newstalkstl.com/ FOLLOW TIM - https://twitter.com/SpeakerTimJones FOLLOW CHRIS - https://twitter.com/chris_arps 24/7 LIVESTREAM - http://bit.ly/NEWSTALKSTLSTREAMS RUMBLE - https://rumble.com/NewsTalkSTL See omnystudio.com/listener for privacy information.
We review the Best Ski Boots for the new 2026 winter season, covering the best piste, all mountain and freeride ski boots. Host Iain Martin was joined by The Ski Podcast's equipment expert Al Morgan and Frazer Shand, Operations Manager at Profeet. This special episode has been made possible by the Profeet Ski Boot Lab, based in south-west London. Profeet offer expert ski boot fitting, custom insoles and ski boot modifications. SHOW NOTES Watch our ‘Best Skis of 2026' video Ski Boot definitions and terms… Shell (4:00) Last (4:30) Mondopoint (5:45) Flex (7:15) Liner (8:45) BOA (10:15) Powerstrap (12:30) Walk mode and Grip Walk (13:30) Sustainability (16:30) Function, Fit and Footbeds (18:15) Find out about the fitting process at the Profeet Ski Boot Lab (18:45) Profeet start with a biomechanical analysis and foot scan (19:45) Custom insoles (23:00) Customisation (24:00) Visiting the Dalbello factory (34:00) Get your free tickets to the London Snow Show (55:45) Profeet will be exhibiting at the London Snow Show (56:30) THE BEST SKI BOOTS OF 2026 Piste and All-Mountain Ski Boots K2 Cortex Zonal 120 BOA(26:30) £625 SIZES (MP): 24.5 - 28.5 VOLUME: Low LAST (mm): 96 – 98 WEIGHT (per boot): 2,179g (26.5MP) These are incredible boots, delivering a ton of support and superb hold, in a flex that will work far better for most skiers. K2 has offered single BOA on higher-volume boots previously, but the Cortex is the slimmest profile they've integrated this into, and this time you get the benefit of the dial and cable system on the shell and cuff, on the Zonal models. Non-Zonal Cortex models have BOA only over the foot. The softer material over the instep makes it a tad easier to get into the boot, and aids shell wrapping, when you dial in the snugness. The heel has a slimmer internal profile than their other boots, and the lace-up liner adds to the excellent hold you get. You also get a cam power strap, which is not that common on 120 flex boots, and I much prefer this strap to a Velcro option. There are two bolts on the spine, and you can remove the top one if you want a more forgiving flex profile. They offer the Cortex range right up to the £725, all-singing, all-dancing 140 flex model, which is the only one with pin inserts in the toe. Dalbello Veloce Space 120 Dual(32:00) £580 SIZES (MP): 24.5 - 30.5 VOLUME: Medium LAST (mm): 101 FLEX: 120 WEIGHT (per boot): 2,050g (27.5MP) This is the first season Dalbello has offered BOA on their boots, and they've added Dual and Single BOA models to their range, in this new Veloce Space line. Dual BOA is available on the 105, 120 and 130 flex models. The shell and cuff on the 120 are made of PU. They inject differing hardnesses of plastic, to take advantage of the phenomenal wrap you get with the BOA system. It also makes the boots easier to get on. The mouldable liner is beautifully comfortable, and the Adaptive Tongue construction, integrating memory foam, is so nice for the shins, also helping with instep comfort. The pre-shaped Ankle Sense zones enhance the heel hold. The 120 is also available in a single BOA (£540), with regular cuff buckle closure, like the 110, 100, 95 and 85. These single BOA versions get a lever you can release on the spine, allowing an easier walking motion. Head Kalibre 110 MV BOA 2(36:00) £510 SIZES (MP): 25.0 - 30.5 VOLUME: Medium LAST (mm): 100 WEIGHT (per boot): No stated weights This is Head's Dual BOA offering and is totally new. The Kalibre boots have a clean aesthetic. They inject different hardnesses or plastic into the shell, to take advantage of the superb wrap of the BOA H+i1 system. Kaliber, like many BOA offerings, is a medium volume fit, with 100mm last. They have a new liner for this range too, called Synapse. They weave in Graphene for tech-level temperature regulation. The 110 has a Velcro power strap, although £600 130 flex has a claw strap. The Kaliber line features a greater range of flexes in single BOA and four clip versions, but the BOA2 models are pretty awesome. This is the only 110 flex dual BOA model we know of for this season. Freeride Ski Boots Rossignol Alltrack 130 Elite LV LT GW (40:30) £625 SIZES (MP): 24.0 – 29.5 WALK MODE: Y, no stated ROM VOLUME: Low LAST (mm): 98 FLEX: 130 WEIGHT (per boot): 1,825g (no stated size) The Alltrack line has been redesigned for this season. They've added BOA to shell of the 102mm HV models, but we tested the narrow-last Elite LT model, which has tech inserts in the toe and heel. Even though these are 98mm last, low-volume boots, they have more room inside than some other LV boots in this category. They look sensational, have heat-mouldable liners and an innovative ski-walk mode, inspired by the work done developing the Vizion easy (rear) entry boots. Flip the ski-walk mode lever up, and the rear of the boot can tilt back, with the liner attached to the rear of the cuff with a loop to hold it in place, in order that you can easily slide in. Fasten the buckles, flex forward and the walk mode locks into the ski position, ready for the descent. To tour, flip the rear lever up, loosen the cuff buckles and power strap, and off you go. This boot skied beautifully, and I just love the way the Dual Core shells flex. Armada AR One 130 (43:00) £580 SIZES (MP): 24.5 - 29.5 WALK MODE: N VOLUME: Medium LAST (mm): 100 FLEX: 130 WEIGHT (per boot):100g (26.5MP) The AR One is Armada's first ever ski boot and it's a very impressive hybrid cabrio design blending Alpine and freeski design. Designed by Armada, it's built in partnership with their sister company, Atomic. It's a medium volume unisex boot, with a 100mm last in a size 26.5MP, in 5 flexes. The 120 and 130 are only available from 24.5MP and up, whilst the 90, 100 and 110 go down to 23.5MP. The heat mouldable shell and liner, along with excellent out-of-the-box shaping, ensures a very comfy, and customisable, fit. A tool free volume adjuster lets you create space for pressured calves, and most parts are user replaceable, improving sustainability. The top three flexes are pure PU shell, cuff and tongue, for a smooth ride. The rubber boot board does a fab job of smoothing landings and judders. The buckle setup is very different, especially the instep buckle and cable Y-configuration, securely holding you in the heel pocket. The 130 and 110 share the Team liner, whilst the others have the Pro Liner, which lacks the repositionable tongue, which allows you to adjust volume and fit over the foot. The elasticate claw power-strap on these two flexes is a superb, but the others only get a Velcro strap. Toe pin inserts on the 130 allows use with hybrid bindings like the Shift, Duke PT and the new ATK Hy. This is a fabulous downhill ski boot, with excellent lateral response, impressive power, it's smooth with great damping and superb heel hold. Scarpa 4 Quattro GT Woman (45:45) £580 SIZES (MP): 22.5 – 27.0 WALK MODE: Y, 61° ROM VOLUME: Medium LAST (mm): 101 FLEX: 90 / 110 WEIGHT (per boot): 1,510g (25.0MP) The 4-Quattro range has been an incredible success, especially the XT model which has been a benchmark freeride touring boot in recent seasons. Scarpa's dropped the XT for this winter, but they've updated the SL, they still have the 4-Quattro Pro, which Nikolai Schirmer uses and helped develop, and they've added in a new GT model in a woman's and man's version. The GT has a roomier fit, has a new 4Pro Flex GT Intuition liner, and is the warmest 4-Quattro model. You get a Velcro power strap, rather than a claw version seen on the others, and it's made using Desmopan plastic for the shell and cuff, rather than Pebax Renew, although all Quattro models have a Pebax tongue. The Desmopan CQ MBC uses bio-circular TPU, enhancing the sustainability, and reducing the CO2 footprint. You don't get the Carbon Core construction of the SL or Pro, but the GT skis better. They're an easier flex for lighter or less aggressive riders, and the fact these are such great value is a bonus. PROFEET'S CHOICE Technica Mach1 LV 130, £550 (48:30) Updated for this season with a fully redesigned shell and liner, offering a touch more instep depth but still an excellent low volume fit. From a boot fitter point of view, they are also a pleasure to work on with design features allowing for easier customisation of the shell. Feedback (51:00) I enjoy all feedback about the show, so if you enjoyed this episode, or if you have any questions about skis we didn't cover, then please let us know by leaving a comment at Instagram or Facebook – we are @theskipodcast – or by dropping me an email theskipodcast@gmail.com. You can also follow us on WhatsApp for exclusive material released ahead of the podcast. Adam Matthews on Instagram enjoyed our ‘Best Skis' episode: “Great podcast. Been looking forward to this since last year's episode” Rick on YouTube loved Al's choice of the Volkl V.Werks 100: “I rode this a lot last winter, so much that I crashed and busted my knee. But seriously, it´s an absolutely amazing ski.” There are now 276 episodes of The Ski Podcast to catch up with. You can do that too, there is so much to listen to in our back catalog, just go to theskipodcast.com and search around the tags and categories: you're bound to find something of interest. If you enjoyed this episode and would like to help the podcast, there are three things you can do: - you can follow us, or subscribe, so you never miss an episode - you can give us a review on Apple Podcasts or leave a comment on Spotify - And, if you're booking ski hire this winter, don't forget that you can help The Ski Podcast and save yourself some money on your ski hire by using the code ‘SKIPODCAST' when you book at intersportrent.com. You'll get a guaranteed additional discount, or simply take this link for your discount to be automatically applied.
1) Momifications au pluriel 1/2: au-delà des terres d'Égypte La momification, souvent associée à l'Égypte, est en réalité une pratique mondiale avec diverses méthodes. Des momies naturelles se forment dans des conditions extrêmes, comme le froid ou la sécheresse. Un sujet d'Anne Baecher. 2) Intelligence artificielle: décoder le langage animal Lʹintelligence artificielle nous permet dʹespérer décoder un jour le langage des autres espèces. Grâce au machine learning, notamment on a pu identifier une sorte de langage des signes chez la seiche, prédire lʹissue dʹune dispute chez les chauves-souris ou encore isoler des phonèmes dans les clics du cachalot. Des langages racontés par Lucia Sillig. 3) Les secrets du cortex Le cortex, l'écorce qui entoure notre volumineux cerveau, est une merveille de fonctionnalité, il joue un rôle dans notre créativité, empathie et régulation des pulsions. S'appuyant sur de nombreux cas cliniques et sur le fruit de ses recherches Richard Lévy dévoile les incroyables pouvoir du cortex, notamment du cortex préfrontal, dans son dernier livre : "Cortex. Percez les secrets de l'intelligence" paru chez Albin Michel en 2025. Un sujet d'Anne Baecher.
Full show: https://kNOwBETTERHIPHOP.com Artists Played: Truly Def, Aubrey West, Juni Ali, conshus, unselftitled, Rick Ross, Venna, Jorja Smith, The Allergies, Andy Cooper, Ego Ella May, Senor Kaos, Illastrate, Supastition, 4-IZE, Say She She, Stik Figa, CORTEX, MoZaic, Arrested Development, Brian Jackson, Omar, Amerigo Gazaway, Cavendish Archive, TzariZM, Oddisee, Mr. Boswell Thomas, Dan Brown, The Jack Moves, Droogie Otis, Killer Mike, OutKast, GOODie MOb, IMAKEMADBEATS
In this episode, Jesse Gordon-Blake, PhD, delves into the intricacies of medicinal chemistry, particularly focusing on drug discovery for ALS (amyotrophic lateral sclerosis). Jesse explains the process of discovering molecules that modulate biological pathways, the difference between structure-based and phenotype-based drug design, and the role computational methods play in drug development. The conversation also explores the challenges of crossing the blood-brain barrier, the importance of validating target response, and the complexities of progressing from a theoretical compound to preclinical studies. Additionally, Jesse touches on the significance of target product profiles, CNS drug design characteristics, and the iterative nature of medicinal chemistry. He concludes by discussing his current projects at Cortex, including fundraising strategies and timelines for drug development.00:00 Introduction to Medicinal Chemistry00:37 Drug Discovery Approaches02:01 Computational Methods in Medicinal Chemistry03:21 Challenges in ALS Drug Discovery04:23 Blood-Brain Barrier and Drug Design05:29 Key Properties for CNS Drug Design08:58 Day-to-Day in Drug Discovery09:45 Early Stage Drug Development12:28 Validating Drug Targets16:15 From Theory to Animal Testing22:46 Funding and Timeline Considerations25:45 Regulatory and Manufacturing Considerations28:32 Conclusion and Contact InformationDr. Jesse Gordon-Blake is an independent biotechnology and drug discovery consultant with expertise in medicinal chemistry and neurotherapeutics. He has led efforts in small molecule and peptide therapeutic development, AI-enabled drug discovery, and biotech startup formation, and currently serves as the CSO of Cortexa Therapeutics. He earned his PhD in Medicinal Chemistry from the University of Illinois at Chicago, focusing on developing innovative small-molecule enzyme modulators for Alzheimer's disease.https://www.linkedin.com/in/jesse-gordon-blake-phd-52a26274/https://www.cortexatherapeutics.com/Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.
In this episode, Dr. Rachel is joined by Dani Perrecone and Paloma Garcia Cruz, co-founders of In the Cortex, a program that helps children and adults overcome hidden neurological blocks through brain reorganization.Dani and Paloma share their personal stories of living with disorganized brains, how they discovered the power of primitive reflex integration, and why so many behavioral, learning, and emotional struggles actually trace back to missed developmental movements in infancy.Together, they explore the science of primitive reflexes, why retained reflexes can sabotage learning and emotional regulation, and how recreating early-life movements can unlock neuroplasticity at any age. From meltdowns over shoes to road rage in adulthood, they explain how unresolved reflexes shape lifelong patterns, and how parents can finally help their kids move past them.We also dive into the systemic issues fueling these challenges, from modern birth interventions and overuse of baby gear to ever-expanding diagnostic criteria. With refreshing honesty and compassion, Dani and Paloma encourage parents to release guilt, embrace hope, and reclaim the natural movements that wire the brain for success.Highlights:Dani and Paloma's journey from disorganized brains to brain reorganization leadersWhat primitive reflexes are, and why they must integrate properlySigns of retained reflexes in children (meltdowns, sensory issues, attention struggles)How reflexes influence posture, coordination, and emotional regulationNeuroplasticity as the foundation of hope, brains can change at any ageThe link between trauma, retained reflexes, and emotional triggersWhy modern lifestyles (swaddling, walkers, devices) disrupt brain developmentPractical ways parents can support reflex integration at homeConscious parenting, grace, and breaking cycles of inherited stressCase stories of children and adults transformed through brain reorganizationAbout Dani & PalomaDani Perrecone and Paloma Garcia Cruz are the founders of In the Cortex, an innovative program that rewires the brain by addressing retained primitive reflexes. With backgrounds in brain reorganization, child development, and neurodevelopmental disorders, they've helped countless families transform learning, behavior, and emotional well-being. Their mission is simple: empower parents and children with tools to unlock the brain's full potential through movement, connection, and conscious parenting.Website: www.inthecortex.comUse code : drrachel for a % off the next group class.
Est-ce que le paracétamol aurait de réelles conséquences sur la grossesse? Les brèves du jour Les secrets du cortex Lʹénurésie nocturne, qu'est-ce que c'est?
Mon, 15 Sep 2025 13:00:00 GMT http://relay.fm/cortex/171 http://relay.fm/cortex/171 Casey Newton – State of the Workflow 171 Myke Hurley Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. clean 5014 Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. This episode of Cortex is sponsored by: Nexos.ai: All-in-one AI platform for enterprises. Get a 14 day free trial now. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Guest Starring: Stephen Hackett and Casey Newton Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Mon, 15 Sep 2025 13:00:00 GMT http://relay.fm/cortex/171 http://relay.fm/cortex/171 Myke Hurley Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. clean 5014 Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. This episode of Cortex is sponsored by: Nexos.ai: All-in-one AI platform for enterprises. Get a 14 day free trial now. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Guest Starring: Stephen Hackett and Casey Newton Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Hypertrophié chez nous les humains, le cortex préfrontal nous permet de décoder le monde, d'orchestrer la pensée, d'anticiper l'action, de peser le pour et le contre et de nous libérer des automatismes. Et si c'était dans le cortex que se nichait notre seul espace de liberté ? Ravis de vous retrouver pour explorer les superpouvoirs du cortex et plus précisément du cortex préfrontal, hypertrophié chez nous les humains. C'est lui le véritable chef d'orchestre de notre cerveau, ce qui fait de nous ce que nous sommes. Pourquoi est-ce grâce à ce cortex que nous avons tous en tête (enfin je l'espère) juste derrière le front, que nous pouvons décoder le monde, orchestrer la pensée, anticiper l'action, peser le pour et le contre, prendre des décisions, être créatifs et sortir des automatismes ? Et si c'était là dans le cortex préfrontal que se nichait notre seul espace de liberté ? Avec Richard Levy, spécialiste du cortex préfrontal, professeur de Neurologie à Sorbonne Université. Pour son ouvrage Cortex : percez les secrets de l'intelligence paru chez Albin Michel. Musiques diffusées pendant l'émission - Okay Temiz, Sylvain Kassap - On Yedi - Celia Kameni – Used.
In this episode of FYI, ARK CEO Cathie Wood and Analyst Nick Grous sit down with Vlad Tenev, Co-Founder and CEO of Robinhood. Together they explore how Robinhood is redefining retail investing and financial services—from expanding access to private markets and tokenized assets to transforming its product ecosystem into a fintech super app.Vlad discusses Robinhood's long-term vision at the intersection of capitalism and democracy, why retail ownership matters more in the age of AI, and how the company is building around the upcoming $124 trillion generational wealth transfer. He also shares the strategic thinking behind Robinhood's expansion into credit, crypto, and international markets, including the development of its own blockchain and stablecoin.Finally, they explore the role of AI in Robinhood's platform evolution, including the launch of Cortex, and the guiding philosophy behind the company's product velocity and value-driven subscription model.Key Points From This Episode:00:00:00 Introduction00:11:10 Cathie and Vlad discuss how navigating the bear market made Robinhood and ARK stronger.00:13:25 Vlad outlines Robinhood's mission and long-term opportunity to empower retail through ownership.00:17:28 ARK's and Robinhood's shared focus on expanding retail access to private markets through innovation and regulation.00:20:45 Why treating retail investors as a first-class constituency is an underutilized advantage for public companies.00:23:32 How Robinhood's product velocity and innovation position it to capture assets during the $124T generational wealth shift.00:24:34 Designing features that work across extended families and using AI to eliminate frictions in moving assets between institutions.00:29:24 How the company decides when to partner, build in-house, or acquire based on speed, capability gaps, and strategic alignment.00:33:16 Vlad explains how Robinhood adapted its crypto strategy across regulatory cycles, culminating in its European tokenization launch.00:39:42 The internal "aha moment" that led to Robinhood's push into tokenizing real-world assets—from equities to real estate.00:43:44 The tradeoff between adopting existing chains and owning the full product experience via Robinhood Chain.00:45:38 How Robinhood sees the stablecoin market evolving—especially in terms of yield, utility, and international access.00:52:40 Breaking down Robinhood's growing credit product suite and the reasoning behind its Sage Home Loans partnership model.00:58:41 How Robinhood is using AI to simplify investing and help users understand market movements and options strategies.01:02:13 The extent to which Robinhood is using fine-tuned AI models across internal operations, especially customer service.01:04:49 Why the traditional view that retail investors aren't “ready” for private markets no longer applies in the internet era.01:07:41 Vlad shares how the company is thinking about retention vs. pricing as Gold adoption scales.01:10:16 Cathie and Vlad reflect on the shared mission to educate investors and broaden access to financial innovation.
Lithium: Not Just for Moods, but for Memories. A new Nature study links low lithium levels in the brain—not the blood—to early Alzheimer's, with mouse data showing memory nearly restored when lithium was reintroduced. In this episode of Blasphemous Nutrition, I unpack the science, the hype, and the hazards: from plaques that “kidnap” lithium, why supplements aren't the go-to, to the foods and waters where this quiet mineral naturally shows up. Eat your veggies, savor your seafood, and pour that mineral water—because lithium might be your brain's unsuspecting guardian.Find Research Citations and Transcript at Blasphemous Nutrition on SubstackWork with AimeePhotography by: Dai Ross PhotographyPodcast Cover Art: Lilly Kate CreativeCHAT ME UP: let me know what's on your mind by texting here! How to Leave a Review on Apple Podcasts Via iOS Device1. Open Apple Podcast App (purple app icon that says Podcasts).2. Go to the icons at the bottom of the screen and choose “search”3. Search for “Blasphemous Nutrition”4. Click on the SHOW, not the episode.5. Scroll all the way down to “Ratings and Reviews” section6. Click on “Write a Review” (if you don't see that option, click on “See All” first)7. Rate the show on a five-star scale (5 is highest rating) and write a review!8. Bask in the glow of doing a good deed that makes a difference!
Mon, 18 Aug 2025 14:00:00 GMT http://relay.fm/cortex/170 http://relay.fm/cortex/170 Simone Giertz – State of the Workflow 170 Myke Hurley Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. clean 4408 Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Simone Giertz Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Simone Giertz - YouTube Yetch Studio The Coat Hinger – Yetch Studio A chair built for your half-dirty clothes - Simone Giertz - YouTube Why I spent 3 years working on a coat hanger - Simone Giertz - YouTube Fusion 360 Patch Cap – Yetch Studio Screwdriver Ring – Yetch Studio Coat Hingers – Foldable Coat Hangers – Kickstarter The Every Day Calendar – Kickstarter The Every Day Goal Calendar – Yetch Studio Spool Table – Yetch Studio What I've learned from 10 years on YouTube - Simone Giertz - YouTube Yetch Studio – Instagram Edge Piece Puzzle – Yetch Studio Why sales is the worst part of my job - Simone Giertz - YouTube Simone's Home Screen Brick Microsoft To Do Microsoft To Do Paper Apps™ TO•DO Notebook – Gladden Design Pencil Dice™ – Gladden Design
Mon, 18 Aug 2025 14:00:00 GMT http://relay.fm/cortex/170 http://relay.fm/cortex/170 Myke Hurley Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. clean 4408 Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Simone Giertz Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Simone Giertz - YouTube Yetch Studio The Coat Hinger – Yetch Studio A chair built for your half-dirty clothes - Simone Giertz - YouTube Why I spent 3 years working on a coat hanger - Simone Giertz - YouTube Fusion 360 Patch Cap – Yetch Studio Screwdriver Ring – Yetch Studio Coat Hingers – Foldable Coat Hangers – Kickstarter The Every Day Calendar – Kickstarter The Every Day Goal Calendar – Yetch Studio Spool Table – Yetch Studio What I've learned from 10 years on YouTube - Simone Giertz - YouTube Yetch Studio – Instagram Edge Piece Puzzle – Yetch Studio Why sales is the worst part of my job - Simone Giertz - YouTube Simone's Home Screen Brick Microsoft To Do Microsoft To Do Paper Apps™ TO•DO Notebook – Gladden Design Pencil Dice™ – Gladden Design
Thu, 17 Jul 2025 13:45:00 GMT http://relay.fm/cortex/169 http://relay.fm/cortex/169 John Gruber – State of the Workflow 169 Myke Hurley Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. clean 5543 Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: John Gruber Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Daring Fireball Daring Fireball: The M4 iPad Pros MacBook Pro - Apple Studio Display - Apple Daring Fireball: Something Is Rotten in the State of Cupertino Getting Things Done - Wikipedia Field Notes Tot Markdown - Wikipedia Daring Fireball: Introducing Markdown Daring Fireball: Markdown The Enthusiast – Myke's New Blog This is how Apple rolls – John Gruber – Macworld The Talk Show Dithering Sandwich Daring Fireball: WWDC 2007 Keynote News Daring Fireball: Dive Into Markdown Daring Fireball: Internal Letter Circulates at Apple -- and Leaks to The Verge -- Pushing Back Against Returning to the Office Apple Extended Keyboard - Wikipedia tinkerBOY ADB Keyboard/Mouse to USB Converter ThinkPad Silent Bluetooth Mouse MarsEdit BBEdit John's Home Screen Daring Fireball: Kotoba: The Best iOS Dictionary App You've Never Heard Of Sequel Sofa Callsheet Tapestry NetNewsWire Ivory Things Sidekick Pocket
Tue, 24 Jun 2025 18:30:00 GMT http://relay.fm/cortex/168 http://relay.fm/cortex/168 Austin Evans – State of the Workflow 168 Myke Hurley Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. clean 5899 Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Zocdoc: Find the right doctor, right now with Zocdoc. Sign up for free. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Austin Evans Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Austin Evans - YouTube iPhone 16 Pro and iPhone 16 Pro Max - Apple iPhone 12 Mini - I'm switching! - Austin Evans - YouTube Samsung Galaxy S25 Edge Why the S25 Edge is BETTER than I thought - Austin Evans - YouTube I'm NEVER Switching Again - Samsung Z Flip 6 - Austin Evans - YouTube iMac - Apple OWC 11-Port Thunderbolt Dock MacBook Pro - Apple Surface Pro – Microsoft Microsoft Recall - Wikipedia Austin's iPhone Home Screen Austin's Android Home Screen Claude Descript The End of YouTubers - Austin Evans - YouTube Google Gemini ChatGPT ChatGPT Thumbnail of Austin Todoist Google Calendar Spotify Google Docs Notion Is DealDash a SCAM? - Austin Evans - YouTube Final Cut Pro for Mac CapCut Mac mini - Apple Slack Adobe Creative Cloud This Is - YouTube Denki - YouTube The Tech of F1 is WILD - Inside Red Bull Racing - Austin Evans - YouTube Frame.io iPad mini - Apple Kindle Paperwhite Steam Deck WF-1000XM5 | Sony Bathys | Focal Arrivé Larson Backpack | TUMI Osmo Pocket 3 - DJI DJI Mic - DJI