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In this episode, we review the high-yield topic of Adrenal Cortex and Medulla from the Endocrine section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
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In this episode of The Evolving Leader, co-hosts Jean Gomes and Scott Allender talk to neurologist and author Adam Zeman about his latest book The Shape of Things Unseen. Together they explore how imagination helps us step outside the here and now, recall the past, and anticipate the future, and why this ability matters more than ever in a world shaped by automation and accelerating change.Adam takes us inside the science of the mind's eye, from aphantasia (the inability to visualise) to hyperphantasia (imagery as vivid as reality), and unpacks what these differences reveal about creativity, culture and leadership. This conversation offers practical insights for leaders on cultivating imagination within organisations, the role of daydreaming in innovation, and how to create environments where ideas can flourish.Further materials from Adam Zeman:Zeman, A. (2025). The Shape of Things Unseen: A New Science of Imagination. Bloomsbury.Zeman, A., Milton, F., Della Sala, S. (2024). “Aphantasia and Hyperphantasia: Exploring imagery vividness extremes.” Cortex, 170, 1–14.Zeman, A. (2024). “Aphantasia: The science of visual imagery absence.” Trends in Cognitive Sciences, 28(3), 189–200. Other reading from Jean Gomes and Scott Allender:Leading In A Non-Linear World (J Gomes, 2023)The Enneagram of Emotional Intelligence (S Allender, 2023)Social:Instagram @evolvingleaderLinkedIn The Evolving Leader PodcastTwitter @Evolving_LeaderBluesky @evolvingleader.bsky.socialYouTube @evolvingleader The Evolving Leader is researched, written and presented by Jean Gomes and Scott Allender with production by Phil Kerby. It is an Outside production.Send a message to The Evolving Leader team
Crash Bandicoot is getting an animated series at Netflix with WildBrain partnering on production. Expect a bright, slapstick tone that leans into classic Crash chaos, with Cortex likely in the villain seat and a deep bench of side characters. We talk why Netflix is a strong home for game adaptations, how this compares to earlier attempts, and what details still need to be announced like casting and a showrunner. This is a nostalgia win for longtime players and an easy on-ramp for kids who are meeting Crash for the first time. 00:00 Crash Bandicoot series announced for Netflix, WildBrain on board00:12 Tone expectations: silly, slapstick, colorful, classic Crash energy00:17 Appeal for families and longtime players00:29 Earlier TV attempt that stalled and why Netflix is a better fit00:34 Track record of game adaptations on Netflix00:45 What we are watching next: casting and showrunner newsNetflix is developing a Crash Bandicoot animated series with WildBrain, aiming for high-energy slapstick and bold visuals.The show targets a wide audience, pairing kid-friendly fun with nostalgia for fans who grew up with the games.A prior version was explored elsewhere but did not move forward, which makes Netflix's infrastructure and history with game adaptations a promising sign.Big open questions remain, including voice cast, showrunner, and release timing.If Netflix taps into Cortex, Crash, and the extended roster of allies and foes, the series has room for episodic humor and fan-service deep cuts.“Crash Bandicoot is coming to Netflix… it should be silly slapstick, very colorful.”“Kids are going to dig it and the parents are going to be like, oh yeah, I played that game.”“We've seen Netflix take video game properties and turn them into really successful animations.”“The next thing we're looking for is casting and who's going to be the showrunner.”“I'm always down for nostalgia.”Enjoy the episode? Follow and subscribe to Geek Freaks, leave a quick rating and review, and share the show with a friend using #GeekFreaks. It helps more fans find the conversation.All news discussed on our shows comes from GeekFreaksPodcast.comFacebook: https://www.facebook.com/thegeekfreakspodcastThreads: https://www.threads.net/@geekfreakspodcastTwitter: https://twitter.com/geekfreakspodInstagram: https://www.instagram.com/geekfreakspodcast/Patreon: https://www.patreon.com/GeekFreakspodcastFrank on Instagram: @franklourence79What do you want most from a Crash Bandicoot series on Netflix, and who would you cast as Crash or Cortex? Send your thoughts for a chance to be featured in a future episode.Crash Bandicoot, Netflix, WildBrain, Video Game Adaptations, Dr. Neo Cortex, Animation, Nostalgia, Geek Freaks, Arcane, Cyberpunk Edgerunners, Tomb Raider, Splinter CellTimestamps and TopicsKey TakeawaysQuotesCall to ActionLinks and ResourcesFollow UsListener QuestionsApple Podcast Tags
Tue, 21 Oct 2025 11:15:00 GMT http://relay.fm/cortex/172 http://relay.fm/cortex/172 David Pierce – State of the Workflow 172 Myke Hurley Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. clean 5352 Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Incogni: Take your personal data back with Incogni! Use code CORTEX with this link and get 60% off an annual plan. Guest Starring: David Pierce Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Tue, 21 Oct 2025 11:15:00 GMT http://relay.fm/cortex/172 http://relay.fm/cortex/172 Myke Hurley Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. clean 5352 Myke talks to The Verge's David Pierce about the workflow behind his Humane AI Pin review, how he collaborates to make podcasts like The Vergecast, and how his Installer newsletter helps him highlight the positive side of the internet each week. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Incogni: Take your personal data back with Incogni! Use code CORTEX with this link and get 60% off an annual plan. Guest Starring: David Pierce Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
What if AI could actually remember like humans do?Biswaroop Bhattacharjee joins Demetrios Brinkmann to challenge how we think about memory in AI. From building Cortex—a system inspired by human cognition—to exploring whether AI should forget, this conversation questions the limits of agentic memory and how far we should go in mimicking the mind.Guest speaker: Biswaroop Bhattacharjee - Senior ML Engineer at Prem AIHost :Demetrios Brinkmann - Founder of MLOps Community~~~~~~~~ ✌️Connect With Us ✌️ ~~~~~~~Catch all episodes, blogs, newsletters, and more: https://go.mlops.community/TYExploreJoin our Slack community [https://go.mlops.community/slack]Follow us on X/Twitter [@mlopscommunity](https://x.com/mlopscommunity) or [LinkedIn](https://go.mlops.community/linkedin)] Sign up for the next meetup: [https://go.mlops.community/register]MLOps Swag/Merch: [https://shop.mlops.community/]#podcast #aiinfrastructure #aiagents #memory
THE TIM JONES AND CHRIS ARPS SHOW 0:00 SEG 1 Hostage says he was treated better after Trump won the election | St. Louis City Sheriff Alfred Montgomery is going to jail to wait for trial | Charlie Kirk’s widow accepts The Medal of Freedom on behalf of Charlie 18:03 SEG 2 DAVID STOKES, Director of Municipal Policy at the Show-Me Institute | TOPIC: Cortex Eminent Domain Extension: St. Louis lawmakers are moving to extend the Cortex innovation district’s eminent domain powers for another five years. Supporters say it’s key to continued growth, while critics question whether the authority is applied fairly across the city. | Cottleville Development Pause: Cottleville is considering a six-month moratorium on certain new housing projects to manage rapid growth. Supporters want time to update zoning rules, while builders warn it could drive development elsewhere. | University City Apartment Plan Faces Pushback: A proposal to build apartments on a rare forested plot faces resistance after a city panel said it could worsen flooding along the River Des Peres. showmeinstitute.org/author/david-stokesx.com/DavidCStokes 35:28 SEG 3 Chris’ Corner is about the guy who burnt down PA’s gov mansion pleading guilty | Trump hates his TIME Magazine cover | Trump on media coverage of Hamas deal | Trafalgar polling https://newstalkstl.com/ FOLLOW TIM - https://twitter.com/SpeakerTimJones FOLLOW CHRIS - https://twitter.com/chris_arps 24/7 LIVESTREAM - http://bit.ly/NEWSTALKSTLSTREAMS RUMBLE - https://rumble.com/NewsTalkSTL See omnystudio.com/listener for privacy information.
We review the Best Ski Boots for the new 2026 winter season, covering the best piste, all mountain and freeride ski boots. Host Iain Martin was joined by The Ski Podcast's equipment expert Al Morgan and Frazer Shand, Operations Manager at Profeet. This special episode has been made possible by the Profeet Ski Boot Lab, based in south-west London. Profeet offer expert ski boot fitting, custom insoles and ski boot modifications. SHOW NOTES Watch our ‘Best Skis of 2026' video Ski Boot definitions and terms… Shell (4:00) Last (4:30) Mondopoint (5:45) Flex (7:15) Liner (8:45) BOA (10:15) Powerstrap (12:30) Walk mode and Grip Walk (13:30) Sustainability (16:30) Function, Fit and Footbeds (18:15) Find out about the fitting process at the Profeet Ski Boot Lab (18:45) Profeet start with a biomechanical analysis and foot scan (19:45) Custom insoles (23:00) Customisation (24:00) Visiting the Dalbello factory (34:00) Get your free tickets to the London Snow Show (55:45) Profeet will be exhibiting at the London Snow Show (56:30) THE BEST SKI BOOTS OF 2026 Piste and All-Mountain Ski Boots K2 Cortex Zonal 120 BOA(26:30) £625 SIZES (MP): 24.5 - 28.5 VOLUME: Low LAST (mm): 96 – 98 WEIGHT (per boot): 2,179g (26.5MP) These are incredible boots, delivering a ton of support and superb hold, in a flex that will work far better for most skiers. K2 has offered single BOA on higher-volume boots previously, but the Cortex is the slimmest profile they've integrated this into, and this time you get the benefit of the dial and cable system on the shell and cuff, on the Zonal models. Non-Zonal Cortex models have BOA only over the foot. The softer material over the instep makes it a tad easier to get into the boot, and aids shell wrapping, when you dial in the snugness. The heel has a slimmer internal profile than their other boots, and the lace-up liner adds to the excellent hold you get. You also get a cam power strap, which is not that common on 120 flex boots, and I much prefer this strap to a Velcro option. There are two bolts on the spine, and you can remove the top one if you want a more forgiving flex profile. They offer the Cortex range right up to the £725, all-singing, all-dancing 140 flex model, which is the only one with pin inserts in the toe. Dalbello Veloce Space 120 Dual(32:00) £580 SIZES (MP): 24.5 - 30.5 VOLUME: Medium LAST (mm): 101 FLEX: 120 WEIGHT (per boot): 2,050g (27.5MP) This is the first season Dalbello has offered BOA on their boots, and they've added Dual and Single BOA models to their range, in this new Veloce Space line. Dual BOA is available on the 105, 120 and 130 flex models. The shell and cuff on the 120 are made of PU. They inject differing hardnesses of plastic, to take advantage of the phenomenal wrap you get with the BOA system. It also makes the boots easier to get on. The mouldable liner is beautifully comfortable, and the Adaptive Tongue construction, integrating memory foam, is so nice for the shins, also helping with instep comfort. The pre-shaped Ankle Sense zones enhance the heel hold. The 120 is also available in a single BOA (£540), with regular cuff buckle closure, like the 110, 100, 95 and 85. These single BOA versions get a lever you can release on the spine, allowing an easier walking motion. Head Kalibre 110 MV BOA 2(36:00) £510 SIZES (MP): 25.0 - 30.5 VOLUME: Medium LAST (mm): 100 WEIGHT (per boot): No stated weights This is Head's Dual BOA offering and is totally new. The Kalibre boots have a clean aesthetic. They inject different hardnesses or plastic into the shell, to take advantage of the superb wrap of the BOA H+i1 system. Kaliber, like many BOA offerings, is a medium volume fit, with 100mm last. They have a new liner for this range too, called Synapse. They weave in Graphene for tech-level temperature regulation. The 110 has a Velcro power strap, although £600 130 flex has a claw strap. The Kaliber line features a greater range of flexes in single BOA and four clip versions, but the BOA2 models are pretty awesome. This is the only 110 flex dual BOA model we know of for this season. Freeride Ski Boots Rossignol Alltrack 130 Elite LV LT GW (40:30) £625 SIZES (MP): 24.0 – 29.5 WALK MODE: Y, no stated ROM VOLUME: Low LAST (mm): 98 FLEX: 130 WEIGHT (per boot): 1,825g (no stated size) The Alltrack line has been redesigned for this season. They've added BOA to shell of the 102mm HV models, but we tested the narrow-last Elite LT model, which has tech inserts in the toe and heel. Even though these are 98mm last, low-volume boots, they have more room inside than some other LV boots in this category. They look sensational, have heat-mouldable liners and an innovative ski-walk mode, inspired by the work done developing the Vizion easy (rear) entry boots. Flip the ski-walk mode lever up, and the rear of the boot can tilt back, with the liner attached to the rear of the cuff with a loop to hold it in place, in order that you can easily slide in. Fasten the buckles, flex forward and the walk mode locks into the ski position, ready for the descent. To tour, flip the rear lever up, loosen the cuff buckles and power strap, and off you go. This boot skied beautifully, and I just love the way the Dual Core shells flex. Armada AR One 130 (43:00) £580 SIZES (MP): 24.5 - 29.5 WALK MODE: N VOLUME: Medium LAST (mm): 100 FLEX: 130 WEIGHT (per boot):100g (26.5MP) The AR One is Armada's first ever ski boot and it's a very impressive hybrid cabrio design blending Alpine and freeski design. Designed by Armada, it's built in partnership with their sister company, Atomic. It's a medium volume unisex boot, with a 100mm last in a size 26.5MP, in 5 flexes. The 120 and 130 are only available from 24.5MP and up, whilst the 90, 100 and 110 go down to 23.5MP. The heat mouldable shell and liner, along with excellent out-of-the-box shaping, ensures a very comfy, and customisable, fit. A tool free volume adjuster lets you create space for pressured calves, and most parts are user replaceable, improving sustainability. The top three flexes are pure PU shell, cuff and tongue, for a smooth ride. The rubber boot board does a fab job of smoothing landings and judders. The buckle setup is very different, especially the instep buckle and cable Y-configuration, securely holding you in the heel pocket. The 130 and 110 share the Team liner, whilst the others have the Pro Liner, which lacks the repositionable tongue, which allows you to adjust volume and fit over the foot. The elasticate claw power-strap on these two flexes is a superb, but the others only get a Velcro strap. Toe pin inserts on the 130 allows use with hybrid bindings like the Shift, Duke PT and the new ATK Hy. This is a fabulous downhill ski boot, with excellent lateral response, impressive power, it's smooth with great damping and superb heel hold. Scarpa 4 Quattro GT Woman (45:45) £580 SIZES (MP): 22.5 – 27.0 WALK MODE: Y, 61° ROM VOLUME: Medium LAST (mm): 101 FLEX: 90 / 110 WEIGHT (per boot): 1,510g (25.0MP) The 4-Quattro range has been an incredible success, especially the XT model which has been a benchmark freeride touring boot in recent seasons. Scarpa's dropped the XT for this winter, but they've updated the SL, they still have the 4-Quattro Pro, which Nikolai Schirmer uses and helped develop, and they've added in a new GT model in a woman's and man's version. The GT has a roomier fit, has a new 4Pro Flex GT Intuition liner, and is the warmest 4-Quattro model. You get a Velcro power strap, rather than a claw version seen on the others, and it's made using Desmopan plastic for the shell and cuff, rather than Pebax Renew, although all Quattro models have a Pebax tongue. The Desmopan CQ MBC uses bio-circular TPU, enhancing the sustainability, and reducing the CO2 footprint. You don't get the Carbon Core construction of the SL or Pro, but the GT skis better. They're an easier flex for lighter or less aggressive riders, and the fact these are such great value is a bonus. PROFEET'S CHOICE Technica Mach1 LV 130, £550 (48:30) Updated for this season with a fully redesigned shell and liner, offering a touch more instep depth but still an excellent low volume fit. From a boot fitter point of view, they are also a pleasure to work on with design features allowing for easier customisation of the shell. Feedback (51:00) I enjoy all feedback about the show, so if you enjoyed this episode, or if you have any questions about skis we didn't cover, then please let us know by leaving a comment at Instagram or Facebook – we are @theskipodcast – or by dropping me an email theskipodcast@gmail.com. You can also follow us on WhatsApp for exclusive material released ahead of the podcast. Adam Matthews on Instagram enjoyed our ‘Best Skis' episode: “Great podcast. Been looking forward to this since last year's episode” Rick on YouTube loved Al's choice of the Volkl V.Werks 100: “I rode this a lot last winter, so much that I crashed and busted my knee. But seriously, it´s an absolutely amazing ski.” There are now 276 episodes of The Ski Podcast to catch up with. You can do that too, there is so much to listen to in our back catalog, just go to theskipodcast.com and search around the tags and categories: you're bound to find something of interest. If you enjoyed this episode and would like to help the podcast, there are three things you can do: - you can follow us, or subscribe, so you never miss an episode - you can give us a review on Apple Podcasts or leave a comment on Spotify - And, if you're booking ski hire this winter, don't forget that you can help The Ski Podcast and save yourself some money on your ski hire by using the code ‘SKIPODCAST' when you book at intersportrent.com. You'll get a guaranteed additional discount, or simply take this link for your discount to be automatically applied.
Das Leben ist ein Ponyhof - Wie funktioniert Lebensfreude? Von Timo Schiemann
In dieser Folge geht es um das Prinzip Feeling is Healing – warum Fühlen so entscheidend für Heilung ist. Ich erkläre, welche Rolle das Nervensystem, die Amygdala, der präfrontale Cortex, die Insula und die sogenannte Cell Danger Response dabei spielen und warum Symptome oft ein Schutzmechanismus sind. Außerdem erfährst du, weshalb wir so häufig im Kopf bleiben und wie wir Schritt für Schritt wieder ins Fühlen kommen können. Am Ende bekommst du eine kleine Praxisübung, mit der du direkt starten kannst. Ganz viel Spaß beim Zuhören. Dein Timo
Sintonía: "Just Pickin´" - Freddy King"Deixa a tristeza" - Neno Exporta Som; "Morro do barraco sem água - Lemos e Debétio; "Seára de Oxalá" - Barbosa; "Can´t Live Without You" - Connie Laverne; "El mercado" - Alex Rodríguez; "Fish & Funjee (Komi ke kenam)" - Lantei Lamptey; "Karam Bani" - Buari; "Handsome Boy (E Wara) Pt 1 & 2" - The Rwenzori´s; "Mammy Hot Daddy Cool" - Big Youth; "Use My Body" - Mavis John; "Chanson d´un jour d´hiver" - CortexTodas las músicas extraídas de la compilación (2xLP) "Mr. Bongo Record Club Volume One" (Mr Bongo, 2016) Escuchar audio
1) Momifications au pluriel 1/2: au-delà des terres d'Égypte La momification, souvent associée à l'Égypte, est en réalité une pratique mondiale avec diverses méthodes. Des momies naturelles se forment dans des conditions extrêmes, comme le froid ou la sécheresse. Un sujet d'Anne Baecher. 2) Intelligence artificielle: décoder le langage animal Lʹintelligence artificielle nous permet dʹespérer décoder un jour le langage des autres espèces. Grâce au machine learning, notamment on a pu identifier une sorte de langage des signes chez la seiche, prédire lʹissue dʹune dispute chez les chauves-souris ou encore isoler des phonèmes dans les clics du cachalot. Des langages racontés par Lucia Sillig. 3) Les secrets du cortex Le cortex, l'écorce qui entoure notre volumineux cerveau, est une merveille de fonctionnalité, il joue un rôle dans notre créativité, empathie et régulation des pulsions. S'appuyant sur de nombreux cas cliniques et sur le fruit de ses recherches Richard Lévy dévoile les incroyables pouvoir du cortex, notamment du cortex préfrontal, dans son dernier livre : "Cortex. Percez les secrets de l'intelligence" paru chez Albin Michel en 2025. Un sujet d'Anne Baecher.
Full show: https://kNOwBETTERHIPHOP.com Artists Played: Truly Def, Aubrey West, Juni Ali, conshus, unselftitled, Rick Ross, Venna, Jorja Smith, The Allergies, Andy Cooper, Ego Ella May, Senor Kaos, Illastrate, Supastition, 4-IZE, Say She She, Stik Figa, CORTEX, MoZaic, Arrested Development, Brian Jackson, Omar, Amerigo Gazaway, Cavendish Archive, TzariZM, Oddisee, Mr. Boswell Thomas, Dan Brown, The Jack Moves, Droogie Otis, Killer Mike, OutKast, GOODie MOb, IMAKEMADBEATS
Show Notes 3 October 2025Story 1: Some Layers of Your Brain Actually Get Stronger as You AgeSource: ScienceAlert.comStory by: Michelle StarrLink: https://www.sciencealert.com/some-layers-of-your-brain-actually-get-stronger-as-you-ageResearch Paper: https://www.nature.com/articles/s41593-025-02013-1Story 2: Engineers harness light to help heart cells beat stronger and healthierSource: Knowridge.com (News from UC Irvine)Link: https://knowridge.com/2025/09/engineers-harness-light-to-help-heart-cells-beat-stronger-and-healthier/Research Paper: https://www.pnas.org/doi/10.1073/pnas.2509467122Story 3: UCSB-designed soft robot intubation device could save livesSource: UC Santa Barbara “The Current”Story by: Sonia FernandezLink: https://news.ucsb.edu/2025/022019/ucsb-designed-soft-robot-intubation-device-could-save-livesResearch Paper: https://doi.org/10.1126/scitranslmed.ads7681Story 4: Wi-Fi sleep monitoring method offers a non-intrusive, accurate alternative to more cumbersome techniquesSource: MedicalXpress.comStory by: David BradleyLink: https://www.msn.com/en-us/health/other/wi-fi-sleep-monitoring-method-offers-a-non-intrusive-accurate-alternative-to-more-cumbersome-techniques/ar-AA1Mn7tvResearch Paper: https://www.inderscience.com/info/inarticle.php?artid=148201Honorable MentionsStory: A new catalyst could make mixed plastic recycling a realitySource: Phys.orgStory by: Robert EganLink: https://phys.org/news/2025-09-catalyst-plastic-recycling-reality.htmlResearch Paper: https://www.nature.com/articles/s41557-025-01892-yStory: A New Solar Panel Shield Made From Onion Peels Outlasted Industry Plastics in TestsSource: ZME ScienceStory by: Tudor TaritaLink: https://www.zmescience.com/ecology/renewable-energy-ecology/a-new-solar-panel-shield-made-from-onion-peels-outlasted-industry-plastics-in-tests/Story: Bio-oil made with corn stalks, wood debris could plug orphaned fossil fuel wellsSource: Iowa State UniversityLink: https://www.news.iastate.edu/news/bio-oil-made-corn-stalks-wood-debris-could-plug-orphaned-fossil-fuel-wellsStory: Biochar yields triple win for cotton: Healthier soil, less water, and 87% less nitrogen runoffSource: Anthropocene MagazineStory by: Emma BryceLink: https://www.realclearscience.com/2025/08/11/biochar_yields_a_triple_win_for_cotton_1127969.html
In this episode, Jesse Gordon-Blake, PhD, delves into the intricacies of medicinal chemistry, particularly focusing on drug discovery for ALS (amyotrophic lateral sclerosis). Jesse explains the process of discovering molecules that modulate biological pathways, the difference between structure-based and phenotype-based drug design, and the role computational methods play in drug development. The conversation also explores the challenges of crossing the blood-brain barrier, the importance of validating target response, and the complexities of progressing from a theoretical compound to preclinical studies. Additionally, Jesse touches on the significance of target product profiles, CNS drug design characteristics, and the iterative nature of medicinal chemistry. He concludes by discussing his current projects at Cortex, including fundraising strategies and timelines for drug development.00:00 Introduction to Medicinal Chemistry00:37 Drug Discovery Approaches02:01 Computational Methods in Medicinal Chemistry03:21 Challenges in ALS Drug Discovery04:23 Blood-Brain Barrier and Drug Design05:29 Key Properties for CNS Drug Design08:58 Day-to-Day in Drug Discovery09:45 Early Stage Drug Development12:28 Validating Drug Targets16:15 From Theory to Animal Testing22:46 Funding and Timeline Considerations25:45 Regulatory and Manufacturing Considerations28:32 Conclusion and Contact InformationDr. Jesse Gordon-Blake is an independent biotechnology and drug discovery consultant with expertise in medicinal chemistry and neurotherapeutics. He has led efforts in small molecule and peptide therapeutic development, AI-enabled drug discovery, and biotech startup formation, and currently serves as the CSO of Cortexa Therapeutics. He earned his PhD in Medicinal Chemistry from the University of Illinois at Chicago, focusing on developing innovative small-molecule enzyme modulators for Alzheimer's disease.https://www.linkedin.com/in/jesse-gordon-blake-phd-52a26274/https://www.cortexatherapeutics.com/Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.
Wenn du trotz bester Vorsätze immer wieder in Stresssituationen scheiterst, liegt das nicht an mangelnder Motivation, sondern an einer Strategie-Lücke, die neurologisch erklärbar ist. Wir tauchen in die Neurobiologie der Gewohnheit ein und klären, warum dein Präfrontaler Cortex (dein rationales Kontrollzentrum) in Krisen "offline" geht und du auf tief verwurzelte Muster zurückgreifst. Anstelle der flüchtigen Motivation brauchst du drei tragende Säulen für dauerhafte Stabilität:Struktur: Feste Routinen und "Wenn-Dann"-Pläne nehmen dir die tägliche Entscheidung ab und programmieren dein Gehirn neu.Nervensystem-Regulation: Da Verlangen oft ein Schrei nach Beruhigung ist, lernst du körperbasierte Techniken (wie die Vagusnerv-Aktivierung), um dich gesund zu erden und innere Spannungen abzubauen.Kognitive Distanz: Du lernst, die automatisierten Gedanken ("Ich brauche das jetzt") als bloße Erzählungen zu erkennen und ihnen durch eine Beobachter-Rolle die Kontrolle zu entziehen.Diese Folge ist für alle, die verstehen wollen, dass wahre Freiheit aus dem fundierten, inneren Aufbau entsteht. Am Ende erhältst du einen klaren Fahrplan mit drei konkreten Schritten, um sofort dein stabiles Fundament für ein alkoholfreies Leben zu bauen. Hast du Fragen oder möchtest mehr erfahren? Schreib mir einfach eine Mail an hi@vladamaettig.com – ich freue mich, von dir zu hören!Du möchtest heute noch in dein Leben ohne Alkohol starten?
In this episode, Dr. Rachel is joined by Dani Perrecone and Paloma Garcia Cruz, co-founders of In the Cortex, a program that helps children and adults overcome hidden neurological blocks through brain reorganization.Dani and Paloma share their personal stories of living with disorganized brains, how they discovered the power of primitive reflex integration, and why so many behavioral, learning, and emotional struggles actually trace back to missed developmental movements in infancy.Together, they explore the science of primitive reflexes, why retained reflexes can sabotage learning and emotional regulation, and how recreating early-life movements can unlock neuroplasticity at any age. From meltdowns over shoes to road rage in adulthood, they explain how unresolved reflexes shape lifelong patterns, and how parents can finally help their kids move past them.We also dive into the systemic issues fueling these challenges, from modern birth interventions and overuse of baby gear to ever-expanding diagnostic criteria. With refreshing honesty and compassion, Dani and Paloma encourage parents to release guilt, embrace hope, and reclaim the natural movements that wire the brain for success.Highlights:Dani and Paloma's journey from disorganized brains to brain reorganization leadersWhat primitive reflexes are, and why they must integrate properlySigns of retained reflexes in children (meltdowns, sensory issues, attention struggles)How reflexes influence posture, coordination, and emotional regulationNeuroplasticity as the foundation of hope, brains can change at any ageThe link between trauma, retained reflexes, and emotional triggersWhy modern lifestyles (swaddling, walkers, devices) disrupt brain developmentPractical ways parents can support reflex integration at homeConscious parenting, grace, and breaking cycles of inherited stressCase stories of children and adults transformed through brain reorganizationAbout Dani & PalomaDani Perrecone and Paloma Garcia Cruz are the founders of In the Cortex, an innovative program that rewires the brain by addressing retained primitive reflexes. With backgrounds in brain reorganization, child development, and neurodevelopmental disorders, they've helped countless families transform learning, behavior, and emotional well-being. Their mission is simple: empower parents and children with tools to unlock the brain's full potential through movement, connection, and conscious parenting.Website: www.inthecortex.comUse code : drrachel for a % off the next group class.
Est-ce que le paracétamol aurait de réelles conséquences sur la grossesse? Les brèves du jour Les secrets du cortex Lʹénurésie nocturne, qu'est-ce que c'est?
I årets høstferie-spesialepisode tar Erlend og Henrik for seg asiatiske baner i spill som for eksempel Banzai Bonsai fra Crash Bandicoot: Wrath of Cortex, Ninja Hideway fra Mario Kart 8 Deluxe med mere. Musikk hentet fra MK8DX og Little Big Planet.Rettelse på episoden: Ice Rink Risk var også med i Mario Party Top 100, så bare lat som at Erlend snakker om den versjonen også når det blir snakket om Ice Rink Risk.Lenker:Spotify - https://open.spotify.com/show/64IL72CmS4EnaNBLI0WFdySpotify for creators - https://creators.spotify.com/pod/show/retropolApple podcasts - https://podcasts.apple.com/us/podcast/retropol/id1537295185?uo=4Pocket Casts - https://pca.st/4hi8admrRadio Public - https://radiopublic.com/retropol-WDE0P9Blue Sky - https://bsky.app/profile/retropol.bsky.social
Mon, 15 Sep 2025 13:00:00 GMT http://relay.fm/cortex/171 http://relay.fm/cortex/171 Casey Newton – State of the Workflow 171 Myke Hurley Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. clean 5014 Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. This episode of Cortex is sponsored by: Nexos.ai: All-in-one AI platform for enterprises. Get a 14 day free trial now. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Guest Starring: Stephen Hackett and Casey Newton Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Mon, 15 Sep 2025 13:00:00 GMT http://relay.fm/cortex/171 http://relay.fm/cortex/171 Myke Hurley Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. clean 5014 Myke talks to Casey Newton about his workflow for running Platformer, from idea capture to writing and publishing, and how he balances reporting with access to some of the most powerful people in tech. This episode of Cortex is sponsored by: Nexos.ai: All-in-one AI platform for enterprises. Get a 14 day free trial now. Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Guest Starring: Stephen Hackett and Casey Newton Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback
Step into a deep, dusty crate-digger's dream with this week's Sunday Funk Groove. This mix blends raw, underground funk and soulful jazz with cinematic energy and dance-floor bounce. Rare Grooves: Deep cuts from Roy Porter Sound Machine, 24 Carat Black, and Newban. Funk & Soul Power: Horn-driven bangers like Pucho & The Latin Soul Brothers' “Got Myself A Good Man.” Jazz Funk Fusion: Psychedelic, cosmic vibes from Cortex and The Awakening. Global Flavors: Latin, Brazilian, and street-funk influences that keep the set fresh and surprising. Perfect for Sunday morning coffee, an afternoon cruise, or getting the living room moving. This mix is a celebration of rhythm, groove, and that undeniable funk attitude. PLAYLIST Roy Porter Sound Machine; George Holmes – Panama - Instrumental 24 Carat Black – 24 Carat Black (Theme) Paz – Laying Eggs Greyboy; Harold Todd – Ruffneck Jazz The Awakening – Slinky Roy Porter Sound Machine – Party Time Soul Expedition – Get Down On It The 3 Pieces – Shortnin'‘ Bread Hysear Don Walker – Satisfaction Pucho & The Latin Soul Brothers – Got Myself A Good Man Newban – Father Time Sherlock Holmes Investigation – Investigation Daniel Salinas – Straussmania Cortex – Huit octobre 1971
► Hier findest du den Human Future Movement Campushttps://kurse.hd5.homodea.com/human-future-movement► Willkommen zu einer ganz besonderen Folge des Human Future Movement-Podcasts.Heute lade ich dich ein, einer Verschwörung auf die Spur zu kommen – allerdings nicht einer, die mit UFOs oder geheimen Eliten zu tun hat. Sondern einer, die uns alle täglich betrifft. Eine Verschwörung, die in unseren Köpfen stattfindet – neurologisch erklärbar, medial befeuert und gesellschaftlich verstärkt.In dieser Episode lernst du die wahren Strippenzieher kennen, die unsere Wahrnehmung auf das Negative verzerren:Die Amygdala – unser innerer Alarmsensor für GefahrDer Hippocampus – unser Erinnerungsmanager, der Muster von Angst verstärktDer anteriore cinguläre Cortex – der uns auf potenzielle Konflikte konditioniertDer Hypothalamus – unser Aufmerksamkeits-Torwächter, der in Stressphasen Positives ausblendetChronischer Stress – der uns im Dauer-Überlebensmodus hältKünstliche Algorithmen – die gezielt unsere Angst triggern, um unsere Aufmerksamkeit zu bindenUnd letztlich: Wir selbst – als Konsument:innen und Erzeuger:innen von InhaltenIch zeige dir, wie du bewusst aus diesem negativen Kreislauf aussteigen kannst.Was wäre, wenn wir anfangen würden, aktiv nach den guten Nachrichten zu suchen – und sie zu teilen?Was wäre, wenn dein nächster Klick nicht von Empörung, sondern von Mitgefühl getragen wird?Diese Episode ist ein liebevoller Weckruf für deine Medienkompetenz, deine Selbstwirksamkeit und dein Vertrauen in das Gute im Menschen.Denn: Wir sind sehr wahrscheinlich viel besser, als wir denken.Lass uns gemeinsam mehr Licht in diese Welt bringen – mutig, ehrlich und verbunden.In Verbundenheit,Veit► Alles zu Veit Lindau: https://go.veitlindau.com/bold-impact► Instagram: https://www.instagram.com/veit.lindau/► Facebook: https://www.facebook.com/veitlindau► Hier geht's zu homodea: http://go.homodea.com/hd191► Instagram: https://www.instagram.com/homodea/► Facebook: https://www.facebook.com/homodea► Schon abonniert? Hier geht's zum Human Future Movement Campus https://kurse.hd5.homodea.com/human-future-movement► Du kannst dir den Podcast überall auf Apple Podcasts, Spotify, meinem Blog, YouTube, SoundCloud und allen Podcastapps kostenlos anhören.► Wir freuen uns sehr, wenn dich die Folge inspiriert. Schreibe uns sehr gern unter podcast@veitlindau.com deine Wünsche für Gäst:innen.► Du möchtest etwas Gutes für die Welt beitragen? Die ichliebedich-Stiftung fördert weltweit integrale Projekte der Potenzialentfaltung und der Kultur des Mitgefühls, besonders für Kinder und Jugendliche.https://ichliebedich-stiftung.de/ich liebe dich-Stiftunghttps://www.paypal.com/paypalme/ichliebedichoderIBAN: DE37 6625 0030 0030 0711 46BIC: SOLADES1BAD#Medienkompetenz #BewusstSein #Positivität #HumanFutureMovement #VeitLindau
Multi-Tenant-Systeme sind besser Single-Tenant-SystemeMultitenant Architekturen sind oft eine unterschätzte Herausforderung in der Softwareentwicklung. Stell dir vor, du betreibst eine Plattform, die tausende Kunden gleichzeitig sauber, performant und sicher bedienen soll – und ein einziger Fehler könnte im schlimmsten Fall alle Daten gleichzeitig gefährden. Klingt nach einem echten Albtraum? Ist es auch! Und genau deshalb tauchen wir in dieser Episode tief in die Welt von Multitenant-Systemen ein.Mit dabei ist Max Schellhorn, AWS Solutions Architect und Experte für SaaS, Cloud und serverless Architekturen. Gemeinsam diskutieren wir, warum Multitenant-Systeme mehr sind als nur ein WHERE-Klausel im SQ-StatementL, wie du echte Daten- und Sicherheitsisolation erreichst, welche Cloud-nativen Mechanismen relevant sind und wie cell-basierte Architekturen im Praxiseinsatz funktionieren.Wir klären was ein klassisches Single-Tenant-Setup ist wann moderne Cell- und Shuffle-Sharding-Konzepte zum Einsatz kommen sollten, räumen mit Mythen auf und liefern handfeste Tipps, wie du als Developer, Cloud Engineer oder CTO dein System flexibel, resilient und kostenoptimiert skalierst – ohne dabei den Fokus auf Security, Margen und Ops zu verlieren. Am Ende weißt du, wie sich Multitenancy modelliert, was wirklich zählt und warum „Multitenant ist das bessere Single Tenant“ mehr als ein Tech-Buzzword ist.Bonus: Im Outro gibt's den vermutlich schlechtesten Gemini-Witz zu Multitenancy.Unsere aktuellen Werbepartner findest du auf https://engineeringkiosk.dev/partnersDas schnelle Feedback zur Episode:
Hypertrophié chez nous les humains, le cortex préfrontal nous permet de décoder le monde, d'orchestrer la pensée, d'anticiper l'action, de peser le pour et le contre et de nous libérer des automatismes. Et si c'était dans le cortex que se nichait notre seul espace de liberté ? Ravis de vous retrouver pour explorer les superpouvoirs du cortex et plus précisément du cortex préfrontal, hypertrophié chez nous les humains. C'est lui le véritable chef d'orchestre de notre cerveau, ce qui fait de nous ce que nous sommes. Pourquoi est-ce grâce à ce cortex que nous avons tous en tête (enfin je l'espère) juste derrière le front, que nous pouvons décoder le monde, orchestrer la pensée, anticiper l'action, peser le pour et le contre, prendre des décisions, être créatifs et sortir des automatismes ? Et si c'était là dans le cortex préfrontal que se nichait notre seul espace de liberté ? Avec Richard Levy, spécialiste du cortex préfrontal, professeur de Neurologie à Sorbonne Université. Pour son ouvrage Cortex : percez les secrets de l'intelligence paru chez Albin Michel. Musiques diffusées pendant l'émission - Okay Temiz, Sylvain Kassap - On Yedi - Celia Kameni – Used.
Hypertrophié chez nous les humains, le cortex préfrontal nous permet de décoder le monde, d'orchestrer la pensée, d'anticiper l'action, de peser le pour et le contre et de nous libérer des automatismes. Et si c'était dans le cortex que se nichait notre seul espace de liberté ? Ravis de vous retrouver pour explorer les superpouvoirs du cortex et plus précisément du cortex préfrontal, hypertrophié chez nous les humains. C'est lui le véritable chef d'orchestre de notre cerveau, ce qui fait de nous ce que nous sommes. Pourquoi est-ce grâce à ce cortex que nous avons tous en tête (enfin je l'espère) juste derrière le front, que nous pouvons décoder le monde, orchestrer la pensée, anticiper l'action, peser le pour et le contre, prendre des décisions, être créatifs et sortir des automatismes ? Et si c'était là dans le cortex préfrontal que se nichait notre seul espace de liberté ? Avec Richard Levy, spécialiste du cortex préfrontal, professeur de Neurologie à Sorbonne Université. Pour son ouvrage Cortex : percez les secrets de l'intelligence paru chez Albin Michel. Musiques diffusées pendant l'émission - Okay Temiz, Sylvain Kassap - On Yedi - Celia Kameni – Used.
Cortex CEO Sam Fiorello with Michael Calhoun discussing C2N Diagnostics, a medical tech company, having big plans to expand its presence in the Cortex Innovation District.
In this episode of FYI, ARK CEO Cathie Wood and Analyst Nick Grous sit down with Vlad Tenev, Co-Founder and CEO of Robinhood. Together they explore how Robinhood is redefining retail investing and financial services—from expanding access to private markets and tokenized assets to transforming its product ecosystem into a fintech super app.Vlad discusses Robinhood's long-term vision at the intersection of capitalism and democracy, why retail ownership matters more in the age of AI, and how the company is building around the upcoming $124 trillion generational wealth transfer. He also shares the strategic thinking behind Robinhood's expansion into credit, crypto, and international markets, including the development of its own blockchain and stablecoin.Finally, they explore the role of AI in Robinhood's platform evolution, including the launch of Cortex, and the guiding philosophy behind the company's product velocity and value-driven subscription model.Key Points From This Episode:00:00:00 Introduction00:11:10 Cathie and Vlad discuss how navigating the bear market made Robinhood and ARK stronger.00:13:25 Vlad outlines Robinhood's mission and long-term opportunity to empower retail through ownership.00:17:28 ARK's and Robinhood's shared focus on expanding retail access to private markets through innovation and regulation.00:20:45 Why treating retail investors as a first-class constituency is an underutilized advantage for public companies.00:23:32 How Robinhood's product velocity and innovation position it to capture assets during the $124T generational wealth shift.00:24:34 Designing features that work across extended families and using AI to eliminate frictions in moving assets between institutions.00:29:24 How the company decides when to partner, build in-house, or acquire based on speed, capability gaps, and strategic alignment.00:33:16 Vlad explains how Robinhood adapted its crypto strategy across regulatory cycles, culminating in its European tokenization launch.00:39:42 The internal "aha moment" that led to Robinhood's push into tokenizing real-world assets—from equities to real estate.00:43:44 The tradeoff between adopting existing chains and owning the full product experience via Robinhood Chain.00:45:38 How Robinhood sees the stablecoin market evolving—especially in terms of yield, utility, and international access.00:52:40 Breaking down Robinhood's growing credit product suite and the reasoning behind its Sage Home Loans partnership model.00:58:41 How Robinhood is using AI to simplify investing and help users understand market movements and options strategies.01:02:13 The extent to which Robinhood is using fine-tuned AI models across internal operations, especially customer service.01:04:49 Why the traditional view that retail investors aren't “ready” for private markets no longer applies in the internet era.01:07:41 Vlad shares how the company is thinking about retention vs. pricing as Gold adoption scales.01:10:16 Cathie and Vlad reflect on the shared mission to educate investors and broaden access to financial innovation.
Lithium: Not Just for Moods, but for Memories. A new Nature study links low lithium levels in the brain—not the blood—to early Alzheimer's, with mouse data showing memory nearly restored when lithium was reintroduced. In this episode of Blasphemous Nutrition, I unpack the science, the hype, and the hazards: from plaques that “kidnap” lithium, why supplements aren't the go-to, to the foods and waters where this quiet mineral naturally shows up. Eat your veggies, savor your seafood, and pour that mineral water—because lithium might be your brain's unsuspecting guardian.Find Research Citations and Transcript at Blasphemous Nutrition on SubstackWork with AimeePhotography by: Dai Ross PhotographyPodcast Cover Art: Lilly Kate CreativeCHAT ME UP: let me know what's on your mind by texting here! How to Leave a Review on Apple Podcasts Via iOS Device1. Open Apple Podcast App (purple app icon that says Podcasts).2. Go to the icons at the bottom of the screen and choose “search”3. Search for “Blasphemous Nutrition”4. Click on the SHOW, not the episode.5. Scroll all the way down to “Ratings and Reviews” section6. Click on “Write a Review” (if you don't see that option, click on “See All” first)7. Rate the show on a five-star scale (5 is highest rating) and write a review!8. Bask in the glow of doing a good deed that makes a difference!
The results from a new longitudinal study contradict classic findings in monkeys but may not warrant a rewriting of the textbooks just yet.
Mon, 18 Aug 2025 14:00:00 GMT http://relay.fm/cortex/170 http://relay.fm/cortex/170 Simone Giertz – State of the Workflow 170 Myke Hurley Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. clean 4408 Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Simone Giertz Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Simone Giertz - YouTube Yetch Studio The Coat Hinger – Yetch Studio A chair built for your half-dirty clothes - Simone Giertz - YouTube Why I spent 3 years working on a coat hanger - Simone Giertz - YouTube Fusion 360 Patch Cap – Yetch Studio Screwdriver Ring – Yetch Studio Coat Hingers – Foldable Coat Hangers – Kickstarter The Every Day Calendar – Kickstarter The Every Day Goal Calendar – Yetch Studio Spool Table – Yetch Studio What I've learned from 10 years on YouTube - Simone Giertz - YouTube Yetch Studio – Instagram Edge Piece Puzzle – Yetch Studio Why sales is the worst part of my job - Simone Giertz - YouTube Simone's Home Screen Brick Microsoft To Do Microsoft To Do Paper Apps™ TO•DO Notebook – Gladden Design Pencil Dice™ – Gladden Design
Mon, 18 Aug 2025 14:00:00 GMT http://relay.fm/cortex/170 http://relay.fm/cortex/170 Myke Hurley Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. clean 4408 Myke talks to Simone Giertz about her workflow for turning ideas into products, from early sketches and CAD prototypes to manufacturing, launching, and running a product studio alongside her YouTube channel. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Factor: Healthy, fully-prepared food delivered to your door. Use code cortex50off Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Simone Giertz Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Simone Giertz - YouTube Yetch Studio The Coat Hinger – Yetch Studio A chair built for your half-dirty clothes - Simone Giertz - YouTube Why I spent 3 years working on a coat hanger - Simone Giertz - YouTube Fusion 360 Patch Cap – Yetch Studio Screwdriver Ring – Yetch Studio Coat Hingers – Foldable Coat Hangers – Kickstarter The Every Day Calendar – Kickstarter The Every Day Goal Calendar – Yetch Studio Spool Table – Yetch Studio What I've learned from 10 years on YouTube - Simone Giertz - YouTube Yetch Studio – Instagram Edge Piece Puzzle – Yetch Studio Why sales is the worst part of my job - Simone Giertz - YouTube Simone's Home Screen Brick Microsoft To Do Microsoft To Do Paper Apps™ TO•DO Notebook – Gladden Design Pencil Dice™ – Gladden Design
Craig sat down with Cam Banks, a prolific RPG creator who has worked on many of the games on your RPG shelf.************************************Support the show for as little as $1 a month: Add this to the end of your link on DriveThruRPG to support the show: ?affiliate_id=1044145Example: https://preview.drivethrurpg.com/en/product/397612/Court-of-Blades--Scandal-Forged-in-the-Dark?affiliate_id=1044145Check out our live-streaming content on Twitch Don't miss our RPG Actual Plays, tutorials, and gaming content on YouTube Listen to an excellent board game podcast Go to the Writer's Room for 7th Sea Adventures!Check out the great games from A Couple of Drakes:Listen to Tales of the ManticoreFollow us on Facebook, Follow on BlueSky
Full show: https://kNOwBETTERHIPHOP.com Artists Played: Overlordz, JBiz, MyGrane McNastee, conshus, MoZaic, MidaZ, Synopse, Travisty the Lazy Emcee, Jewbei, Merna, MRKBH, Rico James, Demae, Skipp Whitman, Tane, Sam-Kun, CORTEX, Kassa Overall, Juni Ali, Wordsworth, The Jack Moves, Yugen Blakrok, MELONYX, The Heart and Brain, Isaiah Irahkiev, M-Dot, Hermanos Gutierrez, Leon Bridges, BuddieRoe, Sly Drexler, OutKast, GOODie MOb, IMAKEMADBEATS
This week on EYE ON NPI we're working without wires - it's the new RM2 module from Raspberry Pi (https://www.digikey.com/en/product-highlight/r/raspberry-pi/radio-module-2-wireless-connectivity) which will let you add 2.4GHz WiFi / Bluetooth LE and Bluetooth Classic over an SDIO interface at a great price. The RM2 is built on the technology stack that Raspberry Pi has been working on for many years in adding built-in wireless to their microcomputers and microcontrollers. For example, starting with the Raspberry Pi 3 (https://www.digikey.com/short/59j9179b), the trading company has been integrating WiFi/Bluetooth to their single-board computers. With tight integration and onboard antenna, it's easy to bring up a new board with networking and native Linux kernel support. To do that, Pi has used the CYW43438 (https://www.digikey.com/short/8pfmdctc) and CYW43455 (https://www.digikey.com/short/99wr3vbq) which supports 2.4G and 5G. When the RP2040 microcontroller chip (https://www.digikey.com/short/bnh55qj4) was released in 2021 along with the Pico board (https://www.digikey.com/short/0p02nwh2) - a year later they came out with the Pico W (https://www.digikey.com/short/bzjt9bcp) for only a few $ more. Instead of trying to design an all-in-one WiFi microcontroller, Pi decided to go the same route they did with the Pi SBC: have a co-processor that adds wireless and then offer the firmware support to make it easy for folks to make IoT projects with a powerful arm Cortex chip. Not surprisingly, the RP2350's Pico 2 also came out with a Pico 2 W (https://www.digikey.com/short/ph2b4dmn) variant pretty quickly. Both W boards have a tinned radio module at the end, reminiscent of the CYW chipsets on the Pi SBCs - in this case they feature the CYW43439 (https://www.digikey.com/short/2tj7twdc) which can do 2.4 GHz WiFi/BT/BLE but not 5GHz to keep the price low. For folks who wanted to built upon the Pico W or 2W with their own design, integrating the CYW43439 (https://www.digikey.com/short/2tj7twdc) is non-trivial: it's a BGA chip which requires adding an antenna, managing traces and impedances as well as getting emitter certifications. So, it's not surprising that Pi trading has designed a standalone module that folks can solder into their designs to take advantage of the high-integration between the RP2 chipset and the CYW43439. The RM2 module (https://www.digikey.com/short/vp58vnh3) comes with antenna, tin and chunky castellated pads that can be pick-and-place'd or hand soldered. We've already seen this module used in some existing designs like the Pico Plus 2W from Pimoroni (https://www.digikey.com/short/rpjcp849). Communication with the CYW43439 (https://www.digikey.com/short/2tj7twdc) inside the module is done over SPI plus some IRQ and reset lines. Note that while, in theory, you could connect this module to any microcontroller with a TCP/IP stack like lwip, it really is only designed and supported with RP2-series microcontrollers. That's because the Pico SDK (https://www.raspberrypi.com/documentation/pico-sdk/networking.html) which integrates the firmware uploading and WiFi stack is not really portable to other microcontrollers and there's a cyw32-driver (https://github.com/georgerobotics/cyw43-driver) that is not open source. We did notice that there's an 'open source' reverse-engineered driver on github (https://github.com/jbentham/picowi) - experimentation will be required for those interested! Bluetooth is more freely licensed via BTStack (https://github.com/bluekitchen/btstack) If you want to add the new RM2 module from Raspberry Pi (https://www.digikey.com/en/product-highlight/r/raspberry-pi/radio-module-2-wireless-connectivity) to your next RP2xxx microcontroller design, for tried-and-tested wireless with lots of platform support, you can pick up some right now from DigiKey! Order today and your fresh modules will ship instantly so you can start integration by tomorrow afternoon. https://www.digikey.com/short/vp58vnh3
From the earliest months of life, we rely on faces to help us navigate the world. They tell us who's safe, who's familiar, and whether they're paying attention to us. But do our responses to faces develop gradually as our brains mature? Or are we born prewired to lock onto the human face. In this episode of Under the Cortex, cognitive scientists Rebecca Saxe of MIT and Heather Kosakowski of Harvard University join host Scott Sleek to discuss their groundbreaking findings, published in Current Directions in Psychological Science, about the development of the brain's face-processing network. If you're interested in learning more about this research, visit psychologicalscience.org. Send us your thoughts and questions at underthecortex@psychologicalscience.org. Under the Cortex is going on hiatus and won't be recording new episodes for the foreseeable future. Explore our archive of 150 episodes filled with scientific insights, stories from editors and researchers, and conversations worth revisiting again and again!
The new study challenges a long-held view that the barrel cortex exclusively encodes sensory signals from the whiskers.
Justin Drake introduces his Lean Ethereum vision. The SEC launches Project Crypto. Alchemy launches the Cortex blockchain engine. And developers discuss concerns over gas limit cap EIP-7825. Read more: https://ethdaily.io/752 Disclaimer: Content is for informational purposes only, not endorsement or investment advice. The accuracy of information is not guaranteed.
Why do we avoid retracing our steps—even when it helps us reach our goals faster? In this episode of Under the Cortex, host Özge Gürcanlı Fischer-Baum speaks with Kristine Cho and Clayton Critcher from the University of California, Berkeley about their latest research on doubling-back aversion: the tendency to resist more efficient paths if they require undoing prior effort. Across four studies involving performance tasks and virtual navigation, Kristine finds that people often choose less efficient strategies simply to avoid feeling like their past actions were a waste. This aversion, while related to the sunk-cost fallacy, has its own unique psychological fingerprint. Tune in to learn how our perceptions of effort, progress, and meaning can lead us astray—even when we know better. If you're interested in learning more about this research, visit psychologicalscience.org. Send us your thoughts and questions at underthecortex@psychologicalscience.org.
Is your engineering team running like the wild, wild west? What does engineering excellence look like in practice?In this episode, Ganesh Datta, co-founder and CTO of Cortex, explores what it takes to achieve engineering excellence. Ganesh shares lessons from his own journey, from early bug-fixing to building a company focused on engineering excellence.We discuss how platform engineering and internal developer platforms (IDPs) can help teams scale, improve reliability, and align with business outcomes. Ganesh also explains why culture, leadership, and clear metrics matter more than any single tool.If you're looking to make your engineering team a true business driver, this conversation is for you.Key topics discussed:How to define engineering excellence and why it's tied to business outcomes.The critical role of leadership in connecting engineering initiatives to business values.When to invest in platform engineering and internal developer platforms as your team grows.Common misconceptions about platform engineering.The importance of clear metrics, shared language, and transparency for continuous improvement.Building a culture that supports operational excellence through rituals and repeated messaging.Real-world examples of using generative AI to accelerate platform adoption and incident analysis.Timestamps:(00:00) Trailer & Intro(01:56) Career Turning Points(07:50) The Practice of Finding the Patterns in Issues(11:39) The Definition of Engineering Excellence(17:10) The Leader's Role in Engineering Excellence(22:31) Aligning Engineering Excellence with the Business Outcomes(26:30) The Importance of Metrics in Engineering Excellence(33:35) The Culture that Drives Engineering Excellence(39:05) Platform Engineering and Internal Developer Platform(45:02) The Biggest Misconception of Platform Engineering or IDP(50:36) Cortex as an Engineering Excellence Platform(52:39) Generative AI Use Case in Platform Engineering(55:26) 3 Tech Lead Wisdom_____Ganesh Datta's BioGanesh Datta is a Co-Founder & CTO of Cortex. Before co-founding Cortex, he was a Principal Software Engineer at Mission Lane where he was responsible for driving the development of real-time underwriting infrastructure. At LendUp, Ganesh was a Senior Software Engineer leading the development and optimization of the company's decisioning infrastructure and financial account management system. Ganesh holds a bachelor of science in computer science from the University of California San Diego.Follow Ganesh:LinkedIn – linkedin.com/in/gsdattaTwitter – x.com/gsdattaWebsite – www.cortex.ioEmail – ganesh@cortex.ioJoin Ganesh & Cortex at IDPCon in NYC – ipdcon.comLike this episode?Show notes & transcript: techleadjournal.dev/episodes/225.Follow @techleadjournal on LinkedIn, Twitter, and Instagram.Buy me a coffee or become a patron.
Thu, 17 Jul 2025 13:45:00 GMT http://relay.fm/cortex/169 http://relay.fm/cortex/169 John Gruber – State of the Workflow 169 Myke Hurley Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. clean 5543 Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: John Gruber Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Daring Fireball Daring Fireball: The M4 iPad Pros MacBook Pro - Apple Studio Display - Apple Daring Fireball: Something Is Rotten in the State of Cupertino Getting Things Done - Wikipedia Field Notes Tot Markdown - Wikipedia Daring Fireball: Introducing Markdown Daring Fireball: Markdown The Enthusiast – Myke's New Blog This is how Apple rolls – John Gruber – Macworld The Talk Show Dithering Sandwich Daring Fireball: WWDC 2007 Keynote News Daring Fireball: Dive Into Markdown Daring Fireball: Internal Letter Circulates at Apple -- and Leaks to The Verge -- Pushing Back Against Returning to the Office Apple Extended Keyboard - Wikipedia tinkerBOY ADB Keyboard/Mouse to USB Converter ThinkPad Silent Bluetooth Mouse MarsEdit BBEdit John's Home Screen Daring Fireball: Kotoba: The Best iOS Dictionary App You've Never Heard Of Sequel Sofa Callsheet Tapestry NetNewsWire Ivory Things Sidekick Pocket
Thu, 17 Jul 2025 13:45:00 GMT http://relay.fm/cortex/169 http://relay.fm/cortex/169 Myke Hurley Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. clean 5543 Myke interviews John Gruber of Daring Fireball. They take a deep-dive into how John's writing takes shape – from capturing ideas and drafting articles to the meticulous editing behind his influential work. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: John Gruber Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Daring Fireball Daring Fireball: The M4 iPad Pros MacBook Pro - Apple Studio Display - Apple Daring Fireball: Something Is Rotten in the State of Cupertino Getting Things Done - Wikipedia Field Notes Tot Markdown - Wikipedia Daring Fireball: Introducing Markdown Daring Fireball: Markdown The Enthusiast – Myke's New Blog This is how Apple rolls – John Gruber – Macworld The Talk Show Dithering Sandwich Daring Fireball: WWDC 2007 Keynote News Daring Fireball: Dive Into Markdown Daring Fireball: Internal Letter Circulates at Apple -- and Leaks to The Verge -- Pushing Back Against Returning to the Office Apple Extended Keyboard - Wikipedia tinkerBOY ADB Keyboard/Mouse to USB Converter ThinkPad Silent Bluetooth Mouse MarsEdit BBEdit John's Home Screen Daring Fireball: Kotoba: The Best iOS Dictionary App You've Never Heard Of Sequel Sofa Callsheet Tapestry NetNewsWire Ivory Things Sidekick Pocket
Tue, 24 Jun 2025 18:30:00 GMT http://relay.fm/cortex/168 http://relay.fm/cortex/168 Austin Evans – State of the Workflow 168 Myke Hurley Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. clean 5899 Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Zocdoc: Find the right doctor, right now with Zocdoc. Sign up for free. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Austin Evans Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Austin Evans - YouTube iPhone 16 Pro and iPhone 16 Pro Max - Apple iPhone 12 Mini - I'm switching! - Austin Evans - YouTube Samsung Galaxy S25 Edge Why the S25 Edge is BETTER than I thought - Austin Evans - YouTube I'm NEVER Switching Again - Samsung Z Flip 6 - Austin Evans - YouTube iMac - Apple OWC 11-Port Thunderbolt Dock MacBook Pro - Apple Surface Pro – Microsoft Microsoft Recall - Wikipedia Austin's iPhone Home Screen Austin's Android Home Screen Claude Descript The End of YouTubers - Austin Evans - YouTube Google Gemini ChatGPT ChatGPT Thumbnail of Austin Todoist Google Calendar Spotify Google Docs Notion Is DealDash a SCAM? - Austin Evans - YouTube Final Cut Pro for Mac CapCut Mac mini - Apple Slack Adobe Creative Cloud This Is - YouTube Denki - YouTube The Tech of F1 is WILD - Inside Red Bull Racing - Austin Evans - YouTube Frame.io iPad mini - Apple Kindle Paperwhite Steam Deck WF-1000XM5 | Sony Bathys | Focal Arrivé Larson Backpack | TUMI Osmo Pocket 3 - DJI DJI Mic - DJI
Tue, 24 Jun 2025 18:30:00 GMT http://relay.fm/cortex/168 http://relay.fm/cortex/168 Myke Hurley Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. clean 5899 Myke kicks off the new ‘State of the Workflow' series with YouTuber Austin Evans. They explore the apps, gear, and systems—like dual phones, YouTube Shorts strategies, and analytics deep dives—that fuel Austin's creativity and 1.5 billion views. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Zocdoc: Find the right doctor, right now with Zocdoc. Sign up for free. Sentry: Mobile crash reporting and app monitoring. Get 6 months of the Team plan free with code cortex. Guest Starring: Austin Evans Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback Austin Evans - YouTube iPhone 16 Pro and iPhone 16 Pro Max - Apple iPhone 12 Mini - I'm switching! - Austin Evans - YouTube Samsung Galaxy S25 Edge Why the S25 Edge is BETTER than I thought - Austin Evans - YouTube I'm NEVER Switching Again - Samsung Z Flip 6 - Austin Evans - YouTube iMac - Apple OWC 11-Port Thunderbolt Dock MacBook Pro - Apple Surface Pro – Microsoft Microsoft Recall - Wikipedia Austin's iPhone Home Screen Austin's Android Home Screen Claude Descript The End of YouTubers - Austin Evans - YouTube Google Gemini ChatGPT ChatGPT Thumbnail of Austin Todoist Google Calendar Spotify Google Docs Notion Is DealDash a SCAM? - Austin Evans - YouTube Final Cut Pro for Mac CapCut Mac mini - Apple Slack Adobe Creative Cloud This Is - YouTube Denki - YouTube The Tech of F1 is WILD - Inside Red Bull Racing - Austin Evans - YouTube Frame.io iPad mini - Apple Kindle Paperwhite Steam Deck WF-1000XM5 | Sony Bathys | Focal Arrivé Larson Backpack | TUMI Osmo Pocket 3 - DJI DJI Mic - DJI
Episode web page: https://bit.ly/4l51qH3 ----------------------- Got a question? Want to recommend a guest? Or do you want to tell me how the show can be better? Send me a voice message via email at podcast@usertesting.com ----------------------- In this episode of Insights Unlocked, we sit down with Dheerja Kaur, Vice President of Product Management at Robinhood, for a deep dive into how thoughtful design, strategic innovation, and customer obsession can transform industries—especially one as complex and regulated as finance. Dheerja brings insights from her journey across major brands like ESPN and The Skimm, sharing how those experiences shaped her unique approach to building products that are not only functional and beautiful but also deeply human. Designing for obsessive user bases: How Dheerja's work with passionate communities—from sports fans to finance enthusiasts—has underscored the value of user loyalty and brand ethos. Democratizing finance through design: A look at how Robinhood lowered economic barriers and emphasized intuitive user experiences to make investing more accessible to everyone. Embracing complexity without sacrificing clarity: Dheerja discusses how her team balances regulatory requirements with elegant product design that promotes user education and confidence. Coaching with ‘Spidey sense': Learn how she develops product intuition in her teams without micromanaging, and how recognizing subtle signals can lead to better outcomes. A culture of experimentation: Why Robinhood encourages teams to pursue bold ideas—even at the risk of failure—and how this fuels long-term growth and innovation. Harnessing real-time insights: Discover how customer feedback from support, surveys, and experimentation informs Robinhood's product strategy and user experience. AI and the future of product design: Dheerja shares Robinhood's early experiments with AI, including the new Cortex product, and how first-principles thinking guides their approach. Championing inclusive leadership: Dheerja reflects on her own experience navigating imposter syndrome and why she prioritizes supporting women and underrepresented groups in tech. Dheerja on LinkedIn: https://www.linkedin.com/in/dheerja/ Robinhood website: https://robinhood.com/ Dheerja's website: https://www.dheerja.com/ Bobby on LinkedIn: https://www.linkedin.com/in/bmeixner Learn more about Insights Unlocked: https://www.usertesting.com/podcast
TransMissions Podcast: Transformers News and Reviews! - All Shows Feed
With the Quartet gathered and Prime Arbiter Cortex ready to speak, Carapace, Sweet Spot, Magnum, and Spindrift stand before the leadership of the Harmonium to receive their long-awaited recognition. A stirring speech from Cortex signals a historic shift—Harmonium will seek alliance with Cybertron. But as rewards are given and honors bestowed, one voice among the Quartet remains conspicuously silent… We want to hear your feedback! Post a comment here or email feedback for Empire Of Rust directly to rust@transmissionspodcast.com! Want some TransMissions swag? Check out our online shop, powered by TeePublic! Like what we’re doing and want to help make our podcast even better? If you already support us, thank you! Show Notes: Intro [0:00:00] Chapter 1 – Harmony In The Harmonium [0:08:37] Chapter 2 – Magnum Maximus [0:30:31] Chapter 3 – Triumphant Return [0:55:29] Closing [1:13:56] If you enjoy Empire of Rust, please rate us and subscribe on Apple Podcasts,… Continue reading The post Empire Of Rust 137 – The Great Machine Gets An Upgrade appeared first on TransMissions Podcast Network.
Thu, 29 May 2025 17:15:00 GMT http://relay.fm/cortex/167 http://relay.fm/cortex/167 Ten Years of Cortex 167 CGP Grey and Myke Hurley Grey and Myke look back on ten years of the show. Grey and Myke look back on ten years of the show. clean 5707 Grey and Myke look back on ten years of the show. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Rocket Money: Cancel unwanted subscriptions and manage your expenses. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Zocdoc: Find the right doctor, right now with Zocdoc. Sign up for free. Links and Show Notes: Special episode artwork illustrated by Ceej Rowland. Get Moretex – More Cortex, with no ads. Submit Feedback Introducing Relay FM's 2015 Summer Pilots — Relay #133: The Ethics of AI Art #134: AI Art Will Make Marionettes Of Us All Before It Destroys The World #59: The 7 Habits of Highly Effective People #165: How to Win Friends and Influence People #119: Thinking, Fast and Slow #120: Episode Out of Time: Rio Heist #143: Apple Vision Pro: Experiencing the Future #32: Dropping Acid #149: Rock, Paper, Scissors Grey's Original Home Screen Myke's Original Home Screens
Fri, 25 Apr 2025 17:45:00 GMT http://relay.fm/cortex/166 http://relay.fm/cortex/166 The Social Network 166 CGP Grey and Myke Hurley Grey and Myke watch the 2010 biopic 'The Social Network'. They discuss their thoughts on the film, its portrayal of Facebook's early days, and how it prompted them to reflect on their own use of social media today. Grey and Myke watch the 2010 biopic 'The Social Network'. They discuss their thoughts on the film, its portrayal of Facebook's early days, and how it prompted them to reflect on their own use of social media today. clean 5466 Subtitle: Cortex Movie ClubGrey and Myke watch the 2010 biopic 'The Social Network'. They discuss their thoughts on the film, its portrayal of Facebook's early days, and how it prompted them to reflect on their own use of social media today. This episode of Cortex is sponsored by: Squarespace: Save 10% off your first purchase of a website or domain using code CORTEX. Rocket Money: Cancel unwanted subscriptions and manage your expenses. Fitbod: Get stronger, faster with a fitness plan that fits you. Get 25% off your membership. Zocdoc: Find the right doctor, right now with Zocdoc. Sign up for free. Links and Show Notes: Get Moretex – More Cortex, with no ads. Submit Feedback The Social Network - Wikipedia DP/30: The Social Network, screenwriter Aaron Sorkin - YouTube The Social Network (soundtrack) - Wikipedia Jesse Eisenberg: I don't want to think of being associated with Mark Zuckerberg - BBC News [iOS 18.4 DB1] New setting for the stock mail app that returns back to inbox after deleting a message instead of automatically going to
In this Huberman Lab Essentials episode, I explain how hormones regulate hunger, appetite and feelings of satiety (fullness), along with strategies to help control appetite. I describe how the body senses nutrient levels and how the brain processes these signals to stimulate hunger or suppress appetite. I also discuss how certain foods can help curb hunger, while processed foods and emulsifiers can interfere with satiety signals, leading to overeating. Additionally, I cover how lifestyle factors such as exercise and meal timing regulate blood glucose levels, which in turn impact hunger and appetite. Huberman Lab Essentials episodes are approximately 30 minutes long and focus on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, while our full-length episodes will continue to be released every Monday. This Huberman Lab Essentials is from the full-length Huberman Lab episode, “How Our Hormones Control Our Hunger, Eating & Satiety.” Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Mateina: https://drinkmateina.com/huberman LMNT: https://drinklmnt.com/huberman For all Huberman Lab sponsors, visit hubermanlab.com/sponsors. Timestamps 00:00:00 Huberman Lab Essentials; Hunger & Appetite 00:00:56 Hunger, Hypothalamus, Cortex & Mouth 00:04:46 Sponsor: David Protein 00:06:02 Melanocyte-Stimulating Hormone, AgRP Neurons, Ghrelin, Tool: Regular Meal Timing 00:10:13 Cholecystokinin (CCK), Tool: Omega-3s, Amino Acids & Blunting Appetite 00:13:26 Sponsor: AG1 00:14:30 Highly-Processed Foods, Emulsifiers, Tool: Whole Foods & Satiety Signals 00:19:10 Insulin, Glucose, Type 1 & 2 Diabetes 00:22:16 Sponsor: Mateina 00:23:41 Insulin & Glucagon, Tools: Food Order, Movement & Blood Glucose 00:27:26 Tool: Exercise & Stable Blood Sugar 00:29:38 Metformin, Ketogenic Diet, Blood Glucose 00:31:59 Sponsor: LMNT 00:33:16 Diabetes, Urine & Blood Sugar 00:35:40 Caffeine, Tool: Yerba Mate, Glucagon-Like Peptide -1 (GLP-1), Appetite 00:38:49 Recap & Key Takeaways Disclaimer & Disclosures
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