Podcasts about bone metastases

Acetabular lesions present unique challenges for interventionalists due to their location within the pelvis. In this episode of the BackTable Podcast, host Dr. Jacob Fleming interviews Dr. Jason Levy, an experienced practitioner in musculoskeletal interventional oncology based in Atlanta, Georgia, about techniques for ablating acetabular lesions. --- This podcast is supported by an educational grant from: Medtronic https://www.medtronic.com/en-us/index.html --- SYNPOSIS The doctors discuss the unique considerations involved in treating the acetabulum, including its susceptibility to various axial loading, shear, and torsion forces. Dr. Levy prefers to use radiofrequency ablation combined with cement augmentation to enhance joint stability. He outlines the procedural steps and shares his preferred imaging methods. Additionally, he addresses potential complications, such as instability from inadequate cement delivery, cement leakage into the hip joint space, and avascular necrosis. Throughout the episode, the doctors emphasize the importance of collaboration with orthopedic oncologists and staying updated on current research in musculoskeletal interventional oncology. --- TIMESTAMPS 00:00 - Introduction 05:11 - Unique Considerations for Acetabular Lesions 09:06 - Collaboration with Orthopedic Oncologists 13:10 - Anatomy and Procedural Steps 24:40 - Preventing Complications 35:25 - Concluding Thoughts --- RESOURCES BackTable MSK Ep. 17- Multidisciplinary Approach to Treating Spinal Metastases with Dr. Jason Levy and Dr. Amir Lavaf: https://www.backtable.com/shows/msk/podcasts/17/multidisciplinary-approach-to-treating-spinal-metastases BackTable VI Ep. 68- RF Ablation Therapy for Bone Metastases with Dr. Jason Levy and Dr. Sandeep Bagla: https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases BackTable MSK Ep. 12- Ortho/IR Collaboration in Private Practice: https://www.backtable.com/shows/msk/podcasts/12/ortho-ir-collaboration-in-private-practice Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study): https://pubmed.ncbi.nlm.nih.gov/33129427/ Hip Joint Distraction Technique during Cryoablation of Acetabular Bone Tumor to Prevent Femoral Head Osteonecrosis: https://www.jvir.org/article/S1051-0443(22)01119-8/fulltext

Acetabular lesions present unique challenges for interventionalists due to their location within the pelvis. In this episode of the BackTable Podcast, host Dr. Jacob Fleming interviews Dr. Jason Levy, an experienced practitioner in musculoskeletal interventional oncology based in Atlanta, Georgia, about techniques for ablating acetabular lesions. --- This podcast is supported by an educational grant from: Medtronic https://www.medtronic.com/en-us/index.html --- SYNPOSIS The doctors discuss the unique considerations involved in treating the acetabulum, including its susceptibility to various axial loading, shear, and torsion forces. Dr. Levy prefers to use radiofrequency ablation combined with cement augmentation to enhance joint stability. He outlines the procedural steps and shares his preferred imaging methods. Additionally, he addresses potential complications, such as instability from inadequate cement delivery, cement leakage into the hip joint space, and avascular necrosis. Throughout the episode, the doctors emphasize the importance of collaboration with orthopedic oncologists and staying updated on current research in musculoskeletal interventional oncology. --- TIMESTAMPS 00:00 - Introduction 05:11 - Unique Considerations for Acetabular Lesions 09:06 - Collaboration with Orthopedic Oncologists 13:10 - Anatomy and Procedural Steps 24:40 - Preventing Complications 35:25 - Concluding Thoughts --- RESOURCES BackTable MSK Ep. 17- Multidisciplinary Approach to Treating Spinal Metastases with Dr. Jason Levy and Dr. Amir Lavaf: https://www.backtable.com/shows/msk/podcasts/17/multidisciplinary-approach-to-treating-spinal-metastases BackTable VI Ep. 68- RF Ablation Therapy for Bone Metastases with Dr. Jason Levy and Dr. Sandeep Bagla: https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases BackTable MSK Ep. 12- Ortho/IR Collaboration in Private Practice: https://www.backtable.com/shows/msk/podcasts/12/ortho-ir-collaboration-in-private-practice Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study): https://pubmed.ncbi.nlm.nih.gov/33129427/ Hip Joint Distraction Technique during Cryoablation of Acetabular Bone Tumor to Prevent Femoral Head Osteonecrosis: https://www.jvir.org/article/S1051-0443(22)01119-8/fulltext

This recording features audio versions of September 2024 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Multidisciplinary Delphi Consensus on Safety of Combining Transarterial Radioembolization with Yttrium-90 Microspheres with Systemic Anticancer Agents for the Treatment of Liver Malignancy ReadImage-Guided Energy Ablation for Palliation of Painful Bony Metastases—A Systematic Review ReadImpact of Percutaneous Cryoablation on Renal Function in Patients with Stage I Renal Cell Carcinoma: A Systematic Review and Meta-Analysis ReadPredictive Factors for Recurrent Hemoptysis after Bronchial Artery Embolization in Patients with Lung Cancer ReadRadiofrequency Ablation in Patients with Interstitial Lung Disease and Lung Neoplasm: A Retrospective Multicenter Study ReadEffectiveness of Genicular Artery Embolization for Reducing Synovitis as Assessed by Contrast-Enhanced MR Imaging in Knee Osteoarthritis: A Pilot Study ReadHepatobiliary Infection after Transjugular Intrahepatic Portosystemic Shunt Creation in Patients with Prior Biliary Intervention: A Multi-Institution Retrospective Study ReadJVIR and SIR thank all those who helped record this episode:Host:Manbir Singh Sandhu, University of California Riverside School of MedicineAudio editor:Sonya Choe, University of California Riverside School of MedicineAbstract readers:Maximillian Hayama, Duke University School of MedicineIsabelle Barbosa, Frank H. Netter MD School of MedicineDaniel Roh, Loma Linda University School of MedicineSiddak Dhaliwal, University of Missouri School of MedicineEric Chang, University of Illinois-Chicago College of MedicineJoy Achuonjei, MD, Northwell HealthMaximillian Denys, University of California Riverside School of MedicineSupport the Show.

Ronald Chen, MD, MPH, FASTRO, hosts a conversation on the background, methodology, primary recommendations, and implications of the updated External Beam Radiation Therapy for Palliation of Symptomatic Bone Metastases: An ASTRO Clinical Practice Guideline. Alongside Tracy Balboni, MD, MPH, and Sara Alcorn, MD, they discuss recent data and changes to practice patterns such as increased use of advanced treatment approaches (e.g., stereotactic radiation) and reirradiation. The guidelines address five key questions in this context, built upon a systematic review of the available literature and with assessment of evidence quality and recommendation strength.

Send us a Text Message.If you ask any rehab professional what scares them the most about oncology patients, their answer 99.9% of the time will be bone metastases.  And this fear is keeping rehab professionals from actually helping their patients with cancer (even those without bone mets).The fact is patients with bone metastases benefit from rehab, from exercise, & from physical activity.  High-quality evidence overwhelmingly supports these benefits & demonstrates that there are very safe ways to administer & dose movement for patients with bone metastases.  Dr. Susan Maltser joins us in this week's replay episode to discuss HOW._______________Writing your oncology specialty exam case report is a huge undertaking.And it's easy to make silly mistakes that can derail your entire writing process.That's why you need my brand new FREE masterclass: The 3 Step Framework for a Finished Case ReportSave your seat at TheOncoPT.com/frameworkFollow TheOncoPT on Instagram.Follow TheOncoPT on TikTok.Follow TheOncoPT on Twitter.

In the first episode of the ACRO podcast CURiE edition, CURiE editor Dr. Jessica Schuster speaks with author Dr. Larry Berk about his published article, "Hemibody Irradiation for Bone Metastases: A Meta-Analysis." Contemporary Updates: Radiotherapy Innovation & Evidence (CURiE) is the official publication platform of the American College of Radiation Oncology through the Cureus Journal of Medical Science.

The Oncology Journal Club - Delivering Oncology News DifferentlyThe Oncology Podcast, brought to you by The Oncology Network, is proud to present Episode 2 in the second series of The Oncology Journal Club.Our Host Professor Craig Underhill has a great interview on onco-burnout. Dr Kate Clarke talks us through breast cancer highlights from 2023 and Professor Christopher Jackson gets stuck into Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases.We also have a fascinating selection of quick bites with the usual high-level analysis and entertaining banter.For papers, bios and other links visit the Show Notes on our website.For the latest oncology news visit www.oncologynews.com.au.We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.The Oncology Podcast - An Australian Oncology Perspective

In this episode of the BackTable Podcast, host Dr. Jacob Fleming and guest Dr. Jack Jennings discuss advancements in interventional oncology, specifically regarding cryoablation for bone metastases. Dr. Jennings is an interventional musculoskeletal radiologist at Washington University School of Medicine and President of the American Society of Spine Radiology. They discuss the results of the MOTION Study, the benefits of industry collaboration, and the future of robotic guidance systems in interventional procedures. They also explain techniques like hydrodissection and pneumodissection in detail. With constant advancements in technology such as guidance navigation systems to reduce pain from bone metastases, it is crucial for interventional radiologists to adapt to these changes. At the end of the episode the doctors give a shout out to the upcoming Society of Interventional Oncology (SIO) 2024 meeting and the enriching opportunities that it offers for interventional radiologists. --- CHECK OUT OUR SPONSOR Boston Scientific Visual ICE Cryoablation System https://www.bostonscientific.com/en-US/products/cryoablation/visual-ice.html --- SHOW NOTES 00:00 - Introduction 02:25 - Overview of the MOTION Study 04:23 - Benefits and Challenges of Cryoablation 09:37 - Results of the MOTION Study 12:13 - Future of Interventional Oncology 19:38 - Role of Imaging Guidance in Cryoablation 23:07 - Future of Robotic Guidance Systems 31:40 - Importance of Industry Partnerships --- RESOURCES Society of Interventional Oncology Annual Meeting, Long Beach, CA January 25th-29th: https://www.sio-central.org/Events/Annual-Scientific-Meeting/Registration Interventional Oncology MOTION Multicenter Study: https://www.bostonscientific.com/en-EU/medical-specialties/interventional-radiology/interventional-oncology/latest-evidence/motion-study.html Percutaneous image-guided cryoablation of painful metastases involving bone: multicenter trial: https://pubmed.ncbi.nlm.nih.gov/23065947/ Cryoablation Needles from Boston Scientific: https://www.bostonscientific.com/en-US/products/cryoablation/visual-ice/visual-ice-cryoablation-needles.htm

In this episode of the BackTable Podcast, host Dr. Jacob Fleming and guest Dr. Jack Jennings discuss advancements in interventional oncology, specifically regarding cryoablation for bone metastases. Dr. Jennings is an interventional musculoskeletal radiologist at Washington University School of Medicine and President of the American Society of Spine Radiology. They discuss the results of the MOTION Study, the benefits of industry collaboration, and the future of robotic guidance systems in interventional procedures. They also explain techniques like hydrodissection and pneumodissection in detail. With constant advancements in technology such as guidance navigation systems to reduce pain from bone metastases, it is crucial for interventional radiologists to adapt to these changes. At the end of the episode the doctors give a shout out to the upcoming Society of Interventional Oncology (SIO) 2024 meeting and the enriching opportunities that it offers for interventional radiologists. --- CHECK OUT OUR SPONSOR Boston Scientific Visual ICE Cryoablation System https://www.bostonscientific.com/en-US/products/cryoablation/visual-ice.html --- SHOW NOTES 00:00 - Introduction 02:25 - Overview of the MOTION Study 04:23 - Benefits and Challenges of Cryoablation 09:37 - Results of the MOTION Study 12:13 - Future of Interventional Oncology 19:38 - Role of Imaging Guidance in Cryoablation 23:07 - Future of Robotic Guidance Systems 31:40 - Importance of Industry Partnerships --- RESOURCES Society of Interventional Oncology Annual Meeting, Long Beach, CA January 25th-29th: https://www.sio-central.org/Events/Annual-Scientific-Meeting/Registration Interventional Oncology MOTION Multicenter Study: https://www.bostonscientific.com/en-EU/medical-specialties/interventional-radiology/interventional-oncology/latest-evidence/motion-study.html Percutaneous image-guided cryoablation of painful metastases involving bone: multicenter trial: https://pubmed.ncbi.nlm.nih.gov/23065947/ Cryoablation Needles from Boston Scientific: https://www.bostonscientific.com/en-US/products/cryoablation/visual-ice/visual-ice-cryoablation-needles.htm

In this episode, host Dr. Eric Keller interviews Dr. Sean Tutton about palliative care as an interventionalist, how he became interested in palliative care, and why he believes it is a crucial aspect of patient care in interventional radiology. --- CHECK OUT OUR SPONSOR RADPAD® Radiation Protection https://www.radpad.com/ --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn free AMA PRA Category 1 CMEs: https://earnc.me/OYDxfn --- SHOW NOTES The role of palliative care is to talk with patients about their goals, make them comfortable, optimize medical management, help patients understand their diagnosis, and coordinate care. Though palliative care involvement does not mean a patient is close to death, many palliative care patients will enroll in hospice at some point. Once in hospice, life-prolonging therapies are no longer pursued. Hospice care is a benefit of Medicare. It has support such as home care, and it can be expensive but is covered by the government. Due to this, there are guidelines that need to be adhered to. Frequently, palliative interventional pain procedures such as a celiac plexus block or neurolysis may not be covered so patients may have to come off hospice to get the procedure, then go back on. Next, we talk about how an IR can start to incorporate these ideals and practices into their daily work. Dr. Tutton emphasizes that you don't need to do the fellowship. You can start rounding with palliative care, go to their conferences, and establish relationships. Having residents and fellows rotate with palliative care is a great way for future IRs to learn how to practice with a palliative care mindset, and also to educate palliative care on the minimally invasive options that IR can offer to patients such as nerve blocks and ablations. By adopting palliative care ideals as an interventionalist, you can help your patients achieve better pain control, improve their cognition and reduce narcotics use. Dr. Tutton recommends all IRs understand the medical management of post-op pain for any procedure they perform. He provides a standard medication regimen for a patient having an ablation. He uses Tylenol 1g pre-op and gabapentin 300-600mg 48-72hrs before the procedure and intraoperative steroids and NSAIDs such as Decadron 8-10mg and Toradol 10-30mg. All of these have level 1 data, help reduce narcotic requirements, and help with post-op nausea and pain. He discharges patients on a Medrol dose pack, ibuprofen, Tylenol, and gabapentin for a couple of days. Doing a nerve block can help as well, he frequently does ankle, digital, intercostal, and hypogastric blocks for his MSK and palliative interventions. --- RESOURCES Ep.199: Advanced Minimally Invasive Pain Interventions with Dr. Prologo https://www.backtable.com/shows/vi/podcasts/199/advanced-minimally-invasive-pain-interventions Ep. 68: RF Ablation for Bone Metastases with Dr. Levy and Dr. Bagla https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases

Drs Sandhya Srinivas and Rana R. McKay discuss bone health and survivorship, including risk factors and potential side effects with androgen deprivation therapy in patients with prostate cancer. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/988732). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Metastases in Prostate Cancer https://pubmed.ncbi.nlm.nih.gov/29661810/ Do Dietary Calcium and Vitamin D Matter in Men With Prostate Cancer? https://pubmed.ncbi.nlm.nih.gov/29765146/ Zoledronic Acid: A Review of Its Use in the Management of Bone Metastases and Hypercalcaemia of Malignancy https://pubmed.ncbi.nlm.nih.gov/12558465/ Denosumab in Osteoporosis https://pubmed.ncbi.nlm.nih.gov/24289327/ Alpha Emitter Radium-223 and Survival in Metastatic Prostate Cancer https://pubmed.ncbi.nlm.nih.gov/23863050/ Effect of Longer-Interval vs Standard Dosing of Zoledronic Acid on Skeletal Events in Patients With Bone Metastases: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/28030702/ The Prevention of Fragility Fractures in Patients With Non-Metastatic Prostate Cancer: A Position Statement by the International Osteoporosis Foundation https://pubmed.ncbi.nlm.nih.gov/29088899/ Decreased Fracture Rate by Mandating Bone Protecting Agents in the EORTC 1333/PEACEIII Trial Combining Ra223 With Enzalutamide Versus Enzalutamide Alone: An Updated Safety Analysis. https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.15_suppl.5002 Addition of Radium-223 to Abiraterone Acetate and Prednisone or Prednisolone in Patients With Castration-Resistant Prostate Cancer and Bone Metastases (ERA 223): A Randomised, Double-Blind, Placebo-Controlled, Phase 3 Trial https://pubmed.ncbi.nlm.nih.gov/30738780/

Interventional Radiologist Jason Levy and Radiation Oncologist Amir Lavaf discuss the benefits of a Multidisciplinary Approach in the Treatment of Spinal and Bone Metastases. --- SHOW NOTES In this episode, Dr. Jason Levy and Dr. Amir Lavaf join Dr. Michael Barraza to discuss their multidisciplinary approach to treating spinal metastases. We examine the collaborative efforts between IR and radiation oncologists, and we break down the indications for treating spinal metastases. We discuss pain control and local control rates, and how doctors are working to improve them. Dr. Levy and Dr. Lavaf tell us why they are able to get better survival numbers when they approach the primary and metastatic disease at the same time. We explain how to work with tumor boards and different groups of doctors to make spinal metastases treatment easier. We discuss how to reduce risk of delayed skeletal events and radiation failure after spinal metastases treatment. We go over some of the challenges of working with the tumor board, and why it is important to develop relationships with medical oncologists and the importance of continuing systemic therapies. --- RESOURCES BackTable Podcast Episode 68: RF Ablation Therapy for Bone Metastases https://www.backtable.com/shows/vi/podcasts/68/rf-ablation-therapy-for-bone-metastases

If you ask any rehab professional what scares them the most about oncology patients, their answer 99.9% of the time will be bone metastases.  And this fear is keeping rehab professionals from actually helping their patients with cancer (even those without bone mets).The fact is patients with bone metastases benefit from rehab, from exercise, & from physical activity.  High-quality evidence overwhelmingly supports these benefits & demonstrates that there are very safe ways to administer & dose movement for patients with bone metastases.  Dr. Susan Maltser is on the podcast today to discuss HOW.Writing your oncology specialty exam case report is a huge undertaking. And it's easy to make silly mistakes that can derail your entire writing process.Make sure you're not forgetting these 5 crucial things when writing your case report!Grab your FREE checklist now! Case Report Writing Workshop is my proven method to transform your blank screen into a complete first draft of your case report, without pulling out your hair in the process. Best of all, it's approved for 8 PT CEU hours! Enroll today at TheOncoPT.com/casereport.Follow TheOncoPT on Instagram.Follow TheOncoPT on TikTok.Follow TheOncoPT on Twitter.

Bone metastases can happen to many people who have cancer. They are most common in people who have breast cancer or prostate cancer. Bone metastases are often painful which is why it's so important to get an early diagnosis to reduce a patient's pain.  Listen in to learn what to expect after being diagnosed with bone metastases. You'll also learn about the different types of bone metastases, the diagnosis process and treatment options.   What You'll Learn: Bone metastases are different from bone cancer. (2:00) Our bodies are always breaking down and building bone. (4:00) There are three types of bone metastases: osteolytic, osteoblastic and mixed. (4:45) The most common symptom is pain. But fractures and elevated calcium levels can also occur. (7:18) Pain from bone metastases is constant and really hard to relieve without treatment. (9:05) To get a diagnosis doctors will typically order x-rays and other scans. (10:10) The most important thing is to get the pain under control as quickly as possible. (14:30) Medications that inhibit the processes of bone resorption are sometimes prescribed. (17:00)  Radiation therapy and radionuclide therapy are two other ways to treat bone metastases. (18:00) Radionuclide is when a patient is injected with radioisotopes for pain relief. (22:24)   Ideas worth sharing: "Though bone metastases are common in certain types of cancer they're possible in all types of cancer." - Dr. Rosalyn Morrell   "If you're experiencing pain, we want to get the pain under control as quickly as possible." - Dr. Rosalyn Morrell   "Usually you can get very rapid pain relief from radiation therapy." - Dr. Rosalyn Morrell   "Which form of therapy you receive is dependent upon your clinical scenario." - Dr. Rosalyn Morrell   "If you have cancer and are feeling pain that feels like it's arising from a bone, inform your healthcare provider. You want to be diagnosed sooner rather than later." - Dr. Rosalyn Morrell   Resources: Rosalyn Morrell, MD: Website

Are Omicron-specific booster shots more effective than the original boosters? Find out about this and more in today's PV Roundup podcast.

Comprehensive, relevant and insightful conversations about health and medicine happen here… on MedStar Health DocTalk. … real conversations with physician experts from around the largest healthcare system in the Maryland-DC region.It takes as much as 1200 to 1800 pounds of pressure to break the human thigh bone. But an unexpected snap of that bone could be the first sign of the one cancer we don't talk enough about: sarcomas, or - bone cancer.  Dr. Albert Aboulafia, head of the Division of Orthopedic Oncology for MedStar Health in Baltimore AND medical director of the Weinberg Cancer Institute at MedStar Franklin Square Medical Center, shares information on bone tumors known as Osteosarcoma. 

In this episode, Chris Parker, MD, and Bertrand Tombal, MD, PhD, discuss the clinical implications of the latest data on radiopharmaceuticals in the treatment of patients with metastatic castration-resistant prostate cancer (CRPC). Topics include:Data from the PEACE-3 trial on the effect of bone-protective agents on fracture risk with enzalutamide plus radium-223Efficacy and toxicity of PSMA lutetium plus standard of care in the VISION trialOngoing trials evaluating radionuclides in combination with other agents in metastatic CRPCPresenters:Chris Parker, MDProfessor of Prostate OncologyInstitute of Cancer ResearchClinical OncologistDepartment of Uro-oncologyRoyal Marsden HospitalSutton, Surrey, United KingdomBertrand Tombal, MD, PhDProfessor of UrologyInstitut de Recherche Clinique (IRC)Cliniques universitaires Saint-LucChairmanDepartment of SurgeryCliniques universitaires Saint-LucBrussels, BelgiumLink to full program, including downloadable slides: https://bit.ly/36IEnNE

Interview with Dr. Catherine Van Poznak, author of Association of Osteonecrosis of the Jaw With Zoledronic Acid Treatment for Bone Metastases in Patients With Cancer

Interview with Dr. Catherine Van Poznak, author of Association of Osteonecrosis of the Jaw With Zoledronic Acid Treatment for Bone Metastases in Patients With Cancer

Ep. 68 RF Ablation Therapy for Bone Metastases with Dr. Jason Levy and Dr. Sandeep Bagla by BackTable

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Dr. Rahul Aggarwal, Oncologist, UCSF. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34970]

Interview with Quynh-Nhu Nguyen, M.D., author of Single-Fraction Stereotactic vs Conventional Multifraction Radiotherapy for Pain Relief in Patients With Predominantly Nonspine Bone Metastases: A Randomized Phase 2 Trial

Interview with Quynh-Nhu Nguyen, M.D., author of Single-Fraction Stereotactic vs Conventional Multifraction Radiotherapy for Pain Relief in Patients With Predominantly Nonspine Bone Metastases: A Randomized Phase 2 Trial

Welcome to Prostate Cancer & You, a series of podcasts sponsored by the Massachusetts Prostate Cancer Coalition. Today's podcast features an interview Adam Kibel, MD, chief, Division of Urology at Brigham and Women's Hospital and the Elliott Carr Cutler professor of surgery in urology, Harvard Medical School. On this podcast he discusses the many changes and advances that have been made in the treatment of prostate cancer in the last several years. He is a member of the MPCC Medical Advisory Committee. At the May 10 Prostate Cancer Symposium he will be a panelist on "Treating the Prostate with Radiation or Surgery in Men with a Small Number of Bone Metastases" with Drs. Paul Nguyen and Matthew Robinson, MD Go here for more information and to register.

Editors’ Summary by Phil B. Fontanarosa, MD, MBA, Executive Editor of JAMA, the Journal of the American Medical Association, for the January 3, 2017 issue

Dr. Benjamin Levy, Mount Sinai Health Systems, compares zoledronic acid and denosumab, two agents used for treatment of bone metastases in lung cancer.

Dr. Benjamin Levy, Mount Sinai Health Systems, compares zoledronic acid and denosumab, two agents used for treatment of bone metastases in lung cancer.

Dr. Benjamin Levy, Mount Sinai Health Systems, compares zoledronic acid and denosumab, two agents used for treatment of bone metastases in lung cancer.

Radiation therapy can be very helpful in treating painful bone metastases or those at risk for causing a fracture due to compromise of bone strength. Dr. Vivek Mehta reviews the basics of this approach. 

Radiation therapy can be very helpful in treating painful bone metastases or those at risk for causing a fracture due to compromise of bone strength. Dr. Vivek Mehta reviews the basics of this approach. 

Radiation therapy can be very helpful in treating painful bone metastases or those at risk for causing a fracture due to compromise of bone strength. Dr. Vivek Mehta reviews the basics of this approach. 

Dr Sten Nilsson from Karolinska University Hospital, Stockholm, Sweden joins ecancer at ASCO GU 2014 to discuss recent data from the phase III ALSYMPCA trial. The discussion includes how radium-223 is an effective treatment against mCRPC and bone metastases.

Background: Breast cancer is the most common malignancy and the second leading cause of death in women. Because bone metastases are a common finding in patients with breast cancer, they are of major clinical concern. Methods: In 115 consecutive patients with bone metastases secondary to breast cancer, 132 surgical procedures were performed. Medical records and imaging procedures were reviewed for age, treatment of the primary tumor, clinical symptoms, surgical treatment, complications, and survival. Results: The overall survival of patients with metastatic breast cancer was dependent on the site and the amount of the metastases. Age was not a prognostic factor for survival. If the result of the orthopaedic surgery was a wide resection (R0) survival was significantly better than in the R1 (marginal resection - tumor resection in sane tissue) or R2 (intralesional resection) situation. Concerning the orthopaedic procedures there was no survival difference. Conclusion: In conclusion a wide (R0) resection and the absence of pathological fracture and visceral metastases were predictive for longer survival in univariate analysis. Age and the type of orthopaedic surgery had no impact on survival in multivariate analysis. The resection margins lost significance. The standard of care for patients with metastatic breast cancer to the bone requires a multidisciplinary approach.

A. Oliver Sartor, M.D Tulane University Hospital New Orleans, LA

Background: Surgery is the primary treatment of skeletal metastases from renal cell carcinoma, because radiation and chemotherapy frequently are not effecting the survival. We therefore explored factors potentially affecting the survival of patients after surgical treatment. Methods: We retrospectively reviewed 101 patients operatively treated for skeletal metastases of renal cell carcinoma between 1980 and 2005. Overall survival was calculated using the Kaplan-Meier method. The effects of different variables were evaluated using a log-rank test. Results: 27 patients had a solitary bone metastasis, 20 patients multiple bone metastases and 54 patients had concomitant visceral metastases. The overall survival was 58% at 1 year, 37% at 2 years and 12% at 5 years. Patients with solitary bone metastases had a better survival (p < 0.001) compared to patients with multiple metastases. Age younger than 65 years (p = 0.036), absence of pathologic fractures (p < 0.001) and tumor-free resection margins (p = 0.028) predicted higher survival. Gender, location of metastases, time between diagnosis of renal cell carcinoma and treatment of metastatic disease, incidence of local recurrence, radiation and chemotherapy did not influence survival. Conclusions: The data suggest that patients with a solitary metastasis or a limited number of resectable metastases are candidates for wide resections. As radiation and chemotherapy are ineffective in most patients, surgery is a better option to achieve local tumor control and increase the survival.