Podcast appearances and mentions of daniel simion

News To Reviews is a video game news and impressions podcast. Each month Zac,  Lachy and an awesome guest sit down to discuss the most interesting stories in gaming and impressions on the latest games. Forget your troubles listening to a bunch of friends talking about what they love most! New episode the first Monday or Tuesday of every month.Anthony's Streaming Channel:https://www.twitch.tv/the_king_greggMatt's Links:https://linktr.ee/hylianstagramNews:Ubisoft is in trouble- 10:38Nintendo Switch 2 details- 20:30Impressions:Split Fiction Review- 1:11:33Monster Hunter: Wilds Review- 1:20:38Assassins Creed: Shadows Impressions- 1:40:00News To Reviews links:https://linktr.ee/newstoreviewsQuestions and Feedback:newstoreviewspodcast@gmail.comPrivacy Policy: https://drive.google.com/file/d/1z8SbxvJ1tbq37XSrJKFb4tynNaFUbjA3/view?usp=sharing© 2019 News to ReviewsSound from http://soundbible.com/“News Intro” by Maximilien (http://soundbible.com/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)Sounds from https://freesound.org/“Kadel 3” by ERH (https://freesound.org/people/ERH/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)Elevator Pitch by PYC Music | https://soundcloud.com/pycmusicMusic promoted by https://www.free-stock-music.comAttribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)https://creativecommons.org/licenses/by-nd/3.0/Sound from http://soundbible.com/“Water Drops Sound” by Daniel Simion (http://soundbible.com/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)

News To Reviews is a video game news and impressions podcast. Each month Zac,  Lachy and an awesome guest sit down to discuss the most interesting stories in gaming and impressions on the latest games. Forget your troubles listening to a bunch of friends talking about what they love most! New episode the first Monday or Tuesday of every month.***Special Guest Anthony***Anthony's Streaming Channel:https://www.twitch.tv/the_king_greggNews:Elden Ring Night Reign release date- 04:12WB games is in trouble- 08:52State of Play February 2025- 20:48Impressions:Helldivers 2 Review- 59:00Monster Train Review- 1:20:45News To Reviews links:https://linktr.ee/newstoreviewsQuestions and Feedback:newstoreviewspodcast@gmail.comPrivacy Policy: https://drive.google.com/file/d/1z8SbxvJ1tbq37XSrJKFb4tynNaFUbjA3/view?usp=sharing© 2019 News to ReviewsSound from http://soundbible.com/“News Intro” by Maximilien (http://soundbible.com/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)Sounds from https://freesound.org/“Kadel 3” by ERH (https://freesound.org/people/ERH/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)Elevator Pitch by PYC Music | https://soundcloud.com/pycmusicMusic promoted by https://www.free-stock-music.comAttribution-NoDerivs 3.0 Unported (CC BY-ND 3.0)https://creativecommons.org/licenses/by-nd/3.0/Sound from http://soundbible.com/“Water Drops Sound” by Daniel Simion (http://soundbible.com/)License: CC BY (https://creativecommons.org/licenses/by/3.0/au/legalcode)

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: September 20, 2018 Apomorphine has a more than 20-year history as a therapeutic adjunct in the management of idiopathic Parkinson disease. And yet, no randomized, placebo-controlled clinical trial to show for it. As of July 2018, now there is. In this week's episode of BrainWaves, Dr. Siegler discusses the relevance, strengths, and weaknesses of the TOLEDO trial. Produced by James E. Siegler. Music by Ondrosik and Rod Hamilton. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCESKatzenschlager R, Poewe W, Rascol O, et al. Apomorphine subcutaneous infusion in patients with Parkinson's disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial. Lancet Neurol 2018;17(9):749-59. PMID 30055903 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: December 13, 2018 Want to make a name for yourself? Declare yourself chief of something. Or chief of many things, as Dr. S A Kinnier Wilson did. This week on the podcast, we commemorate his legacy and his commitment to neurology. Produced by James E Siegler. Music by Chris Zabriskie and Mystery Mammal. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCESCompston A. Progressive lenticular degeneration: a familial nervous disease associated with cirrhosis of the liver, by S. A. Kinnier Wilson, (From the National Hospital, and the Laboratory of the National Hospital, Queen Square, London) Brain 1912: 34; 295-509. Brain 2009;132(Pt 8):1997-2001. PMID 19634211S. A. Kinnier Wilson (1878-1937) Lenticular-hepatic degeneration. JAMA 1968;205(12):871-2. PMID 4877350Trocello JM, Broussolle E, Girardot-Tinant N, et al. Wilson's disease, 100 years later…. Rev Neurol (Paris) 2013;169(12):936-43. PMID 24119853Walshe JM. History of Wilson disease: a personal account. Handb Clin Neurol 2017;142:1-5. PMID 28433095 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: October 18, 2018 What do gardeners and snow skiers have in common? Well, besides the fact that both tend to enjoy the outdoors, it turns out they are also at an increased risk of peripheral nerve injury. This week on the podcast, we review the anatomy and pathophysiology of several of the most common sites of nerve damage in the lower extremity. Produced by James E Siegler. Music by Lee Rosevere. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCESBaima J, Krivickas L. Evaluation and treatment of peroneal neuropathy. Curr Rev Musculoskelet Med 2008;1(2):147-53. PMID 19468889Marciniak C. Fibular (peroneal) neuropathy: electrodiagnostic features and clinical correlates. Phys Med Rehabil Clin N Am 2013;24(1):121-37. PMID 23177035Stewart JD. Foot drop: where, why and what to do? Pract Neurol 2008;8(3):158-69. PMID 18502948 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.Originally released: December 26, 20192019 was a big year. The year of the Mueller report. The American college admissions scandals. Brexit. But it was also the year the US Women's team won the World Cup and lobbied for the equal pay of women and men in sports. It was the year of NMO, in which several pivotal trials showed the benefit of disease-modulating therapy in this condition. The year Will Smith played Genie in Aladdin.2019 was a great year. And as we wrap up 2019, this week's episode includes some of the highlights. Enjoy!Produced by James E Siegler with support from Erika Mejia, Rajat Dhar, and the entire Siegler family. Music courtesy of Axletree, Chris Zabriskie, John Paston, Kevin Mcleod, Josh Woodward, Steve Combs, Lee Rosevere, Scott Holmes, Advent Chamber Orchestra, Coldnoise, and Pachyderm. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast.REFERENCES[BRAIN FOOD]Devore EE, Kang JH, Breteler MM, Grodstein F. Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol 2012;72(1):135-43. PMID 22535616Kennedy DO, Wightman EL, Reay JL, et al. Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. Am J Clin Nutr 2010;91(6):1590-7. PMID 20357044Lefèvre-Arbogast S, Gaudout D, Bensalem J, et al. Pattern of polyphenol intake and the long-term risk of dementia in older persons. Neurology 2018;90(22):e1979-e1988. PMID 29703769Liu QP, Wu YF, Cheng HY, et al. Habitual coffee consumption and risk of cognitive decline/dementia: A systematic review and meta-analysis of prospective cohort studies. Nutrition 2016;32(6):628-36. PMID 26944757Miller MG, Hamilton DA, Joseph JA, Shukitt-Hale B. Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial. Eur J Nutr 2018;57(3):1169-80. PMID 28283823Morris MC, Tangney CC, Wang Y, et al. MIND diet slows cognitive decline with aging. Alzheimers Dement 2015;11(9):1015-22. PMID 26086182Newman JC, Covarrubias AJ, Zhao M, et al. Ketogenic diet reduces midlife mortality and improves memory in aging mice. Cell Metab 2017;26(3):547-57.e8. PMID 28877458Norton S, Matthews FE, Barnes DE, Yaffe K, Brayne C. Potential for primary prevention of Alzheimer's disease: an analysis of population-based data. Lancet Neurol 2014;13(8):788-94. Erratum in: Lancet Neurol 2014;13(11):1070. PMID 25030513Okkersen K, Jimenez-Moreno C, Wenninger S, et al. Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial. Lancet Neurol 2018;17(8):671-80. PMID 29934199Radd-Vagenas S, Duffy SL, Naismith SL,

John and Mandi grease back their hair and put on their leather jackets for 2023's DARK HARVEST. Can they 1960's style rampage their way through small town conspiracies involving corn harvests, murderous malevolent pumpkin beasts, and hilarious amounts of gore? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Background Music: Within the Shadows by Karl Casey @ White Bat Audio DARK HARVEST (2023) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021.Originally released: November 14, 2019The FDA label for ACTEMRA® (tocilizumab)--the first medication approved for use in giant cell arteritis in 2017--is 40 pages long. Of the information provided in this document, which includes important dosing information, dose adjustments based on leukocyte count, clinical trial and epidemiologic data, there is a box of text on the first page of the insert. "WARNING: RISK OF SERIOUS INFECTIONS," it reads.What do you make of this warning? And with such a clear and broad-sweeping statement stamped on the medication, how do you mitigate the medico-legal risk of using this drug?This week on the program we launch into a two-part series focused on some of the events that follow major clinical trials. In part 1, we cover the three major classifications of FDA alerts for medical treatments using two examples from the neurologic pharmacopoeia. In part 2, we emphasize the importance of post-publication peer review. And both are equally instrumental in our medical decision-making.Produced by James E Siegler with the support of Michael Rubenstein (University of Pennsylvania) and Zachary Newcomer (University of Florida). Music courtesy of Coldnoise, Cuicuitte, Doctor Turtle, Jahzzar, and Peter Rudenko under a CC license. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. None of what is discussed here should be misconstrued as medical advice, so don't just go prescribing drugs off-label! (Or willy nilly, as my grandmother might say) Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast.REFERENCESBallard C, Hanney ML, Theodoulou M, et al. The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial. Lancet Neurol 2009;8(2):151-7. PMID 19138567Dorsey ER, Beck CA, Darwin K, et al. Natural history of Huntington disease. JAMA Neurol 2013;70(12):1520-30. PMID 24126537Hubers AA, van Duijn E, Roos RA, et al. Suicidal ideation in a European Huntington's disease population. J Affect Disord 2013;151(1):248-58. PMID 23876196Moore TJ, Singh S, Furberg CD. The FDA and new safety warnings. Arch Intern Med 2012;172(1):78-80. PMID 22232155Rose RV, Kass JS. Prescribing antipsychotic medications to patients with dementia: boxed warnings and mitigation of legal liability. Continuum (Minneap Minn) 2019;25(1):254-9. PMID 30707196Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA 2005;294(15):1934-43. PMID 16234500Schultz JL, Killoran A, Nopoulos PC, Chabal CC, Moser DJ, Kamholz JA. Evaluating depression and suicidality in tetrabenazine users with Huntington disease. Neurology 2018;91(3):e202-7. PMID 29925548Shen V, Clarence-Smith K, Hunter C, Jankovic J. Safety and efficacy of tetrabenazine and use of concomitant medications during long-term, open-label treatment of chorea associated with Huntington's an

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: November 28, 2019 Peer review prior to publication of medical data dates back to the 9th century CE but has only really gained steam in the past 70 or 80 years. Ideally, peer review would serve as an initial filter for data that enter a permanent public scientific record. But peer review is not without flaws. In the second installment of the BrainWaves segment, “It's not over yet…,” we discuss publication as a potential source of bias and highlight the reasons why it should not be the final step of the peer review process. Produced by James E Siegler. Music courtesy of Cullah, Lee Rosevere, John Bartmann, Kevin McLeod, and Jon Watts. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Bingham C, van der Weyden MB. Peer review on the Internet: launching eMJA peer review study 2. Med J Aust 1998;169(5):240-1. PMID 9762058Godlee F, Gale CR, Martyn CN. Effect on the quality of peer review of blinding reviewers and asking them to sign their reports: a randomized controlled trial. JAMA 1998;280(3):237-40. PMID 9676667Haffar S, Bazerbachi F, Murad MH. Peer review bias: a critical review. Mayo Clin Proc 2019;94(4):670-6. PMID 30797567Jefferson T, Alderson P, Wager E, Davidoff F. Effects of editorial peer review: a systematic review. JAMA 2002;287(21):2784-6. PMID 12038911Jefferson T, Rudin M, Brodney Folse S, Davidoff F. Editorial peer review for improving the quality of reports of biomedical studies. Cochrane Database Syst Rev 2007;2007(2):MR000016. PMID 17443635Mandavilli A. Peer review: Trial by Twitter. Nature 2011;469(7330):286-7. PMID 21248816Ware M. Peer review: Benefits, perspectives, and alternatives. Publishing Research Consortium, 2008. We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

Mandi and John try to keep their heads forward and turn the subtitles on for 2019's THE VIGIL. Can they bone crack their way through giant exposition basement TVs, mouth hair, and working very hard to hear the dialog over sound effects and music? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Background Music: Within the Shadows by Karl Casey @ White Bat Audio THE VIGIL (2019) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021.Originally released: October 17, 2019College is a tough time for any kid. But it should also be exciting. Then to experience the freedoms of young adulthood, only later to face the horrifying reality of a progressive neurodegenerative condition...it's not something anyone should experience. In this week's continuation of the patient narrative series, Dr. Paul McIntosh (Duke) shares his life-changing story and his optimism about surviving a chronic neurologic illness.Produced by James E Siegler with the help of Paul McIntosh. For more information about Pompe Disease, check out the resources provided by the United Pompe Foundation at unitedpompe.com. Music for our program this week was courtesy of Ars Sonor, Franz Danzi, Lee Rosevere, and Scott Holmes. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast.REFERENCESBeltran Papsdorf TB, Howard JF Jr, Chahin N. Pearls & Oy-sters: clues to the diagnosis of adult-onset acid maltase deficiency. Neurology 2014;82(9):e73-5. PMID 24590251Cupler EJ, Berger KI, Leshner RT, et al. Consensus treatment recommendations for late-onset Pompe disease. Muscle Nerve 2012;45(3):319-33. PMID 22173792Gutiérrez-Rivas E, Bautista J, Vílchez JJ, et al. Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: a Spanish cohort. Neuromuscul Disord 2015;25(7):548-53. PMID 25998610Kishnani PS, Howell RR. Pompe disease in infants and children. J Pediatr 2004;144(5 Suppl):S35-43. PMID 15126982Kishnani PS, Corzo D, Nicolino M, et al. Recombinant human acid [alpha]-glucosidase: major clinical benefits in infantile-onset Pompe disease. Neurology 2007;68(2):99-109. PMID 17151339Klinge L, Straub V, Neudorf U, et al. Safety and efficacy of recombinant acid alpha-glucosidase (rhGAA) in patients with classical infantile Pompe disease: results of a phase II clinical trial. Neuromuscul Disord 2005;15(1):24-31. PMID 15639117Lukacs Z, Nieves Cobos P, Wenninger S, et al. Prevalence of Pompe disease in 3,076 patients with hyperCKemia and limb-girdle muscular weakness. Neurology 2016;87(3):295-8. PMID 27170567Van den Hout JM, Kamphoven JH, Winkel LP, et al. Long-term intravenous treatment of Pompe disease with recombinant human alpha-glucosidase from milk. Pediatrics 2004;113(5):e448-57. PMID 15121988van der Ploeg AT, Clemens PR, Corzo D, et al. A randomized study of alglucosidase alfa in late-onset Pompe's disease. N Engl J Med 2010;362(15):1396-406. PMID 20393176Wokke JH, Escolar DM, Pestronk A, et al. Clinical features of late-onset Pompe disease: a prospective cohort study. Muscle Nerve 2008;38(4):1236-45. PMID 18816591We believe that

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: August 22, 2019 This week on the BrainWaves podcast, finally...a REAL show about BRAINWAVES! Dr. Carolina Maciel of the University of Florida schools Jim Siegler on how to read EEG and interpret abnormal patterns across the ictal-interictal continuum. Produced by James E Siegler and Carolina Maciel. Music courtesy of Chris Zabriskie, Montplaisir, Rafael Archangel, Steve Combs, Unheard Music Concepts, and Siddhartha. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Benbadis SR, LaFrance WC Jr, Papandonatos GD, et al. Interrater reliability of EEG-video monitoring. Neurology 2009;73(11):843-6. PMID 19752450Beniczky S, Hirsch LJ, Kaplan PW, et al. Unified EEG terminology and criteria for nonconvulsive status epilepticus. Epilepsia 2013;54 Suppl 6:28-9. PMID 24001066Chong DJ, Hirsch LJ. Which EEG patterns warrant treatment in the critically ill? Reviewing the evidence for treatment of periodic epileptiform discharges and related patterns. J Clin Neurophysiol 2005;22(2):79-91. PMID 15805807Claassen J. How I treat patients with EEG patterns on the ictal-interictal continuum in the neuro ICU. Neurocrit Care 2009;11(3):437-44. PMID 19851892Gaspard N, Hirsch LJ, LaRoche SM, Hahn CD, Westover MB; Critical Care EEG Monitoring Research Consortium. Interrater agreement for Critical Care EEG Terminology. Epilepsia 2014 ;55(9):1366-73. PMID 24888711Gerber PA, Chapman KE, Chung SS, et al. Interobserver agreement in the interpretation of EEG patterns in critically ill adults. J Clin Neurophysiol 2008;25(5):241-9. PMID 18791475Hirsch LJ, LaRoche SM, Gaspard N, et al. American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2012 version. J Clin Neurophysiol 2013;30(1):1-27. PMID 23377439Newey CR, Sahota P, Hantus S. Electrographic features of lateralized periodic discharges stratify risk in the interictal-ictal continuum. J Clin Neurophysiol 2017;34(4):365-9. PMID 28166083Rubinos C, Reynolds AS, Claassen J. The ictal-interictal continuum: to treat or not to treat (and how)? Neurocrit Care 2018;29(1):3-8. PMID 29139014 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

ESAT3AM returns with every glass shattered and multiple calls from the network with 2023's LATE NIGHT WITH THE DEVIL. Can they keep their ratings up in spite of cold reading regurgitating psychics, mesmeric worm obsessed skeptics and an ending with Kubrickian levels of weird stuff to unpack? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Background Music:Within the Shadows by Karl Casey @ White Bat Audio LATE LIGHT WITH THE DEVIL(2023) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: August 8, 2019 Clean up on aisle 4! Or should it be IL-4? In this week's installment of the BrainWaves Podcast, we immerse ourselves into the microscopic environment of Alzheimer disease pathology. It's interesting, it's messy, and whoever made this mess is also responsible for the clean-up. Produced by James E Siegler. Music courtesy of Andy Cohen, Brendan Kinsella, Cuicuitte, Damiano Baldoni, Kai Engel, Nctrnm. Sound effects by Mike Koenig, Blastfx.com, Caroline Ford, Robertv, and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Arranz AM, De Strooper B. The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications. Lancet Neurol 2019;18(4):406-14. PMID 30795987Breitner JC, Baker LD, Montine TJ, et al. Extended results of the Alzheimer's disease anti-inflammatory prevention trial. Alzheimers Dement 2011;7(4):402-11. PMID 21784351Chun H, Lee CJ. Reactive astrocytes in Alzheimer's disease: a double-edged sword. Neurosci Res 2018;126:44-52. PMID 29225140Heneka MT, Carson MJ, El Khoury J, et al. Neuroinflammation in Alzheimer's disease. Lancet Neurol 2015;14(4):388-405. PMID 25792098Kumar A, Singh A, Ekavali. A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacol Rep 2015;67(2):195-203. PMID 25712639Maragakis NJ, Rothstein JD. Mechanisms of disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2006;2(12):679-89. PMID 17117171Mattsson N, Zetterberg H, Hansson O, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA 2009;302(4):385-93. PMID 19622817Wisniewski T, Konietzko U. Amyloid-beta immunisation for Alzheimer's disease. Lancet Neurol 2008;7(9):805-11. PMID 18667360Yan R, Vassar R. Targeting the β secretase BACE1 for Alzheimer's disease therapy. Lancet Neurol 2014;13(3):319-29. PMID 24556009 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: May 30, 2019 Since January 1, 2019, there have been nearly 900 confirmed measles cases across 24 states in the United States. This is 10 times greater than the number of cases in the US 3 years ago, and it is the largest outbreak the US has seen since 1994. The month of May also marks the first reported case of measles in the state of Pennsylvania, where BrainWaves is produced. So this week on the program, Jim Siegler speaks with Dr. Erika Mejia (pediatrician) about the medical and sociopolitical triggers for this outbreak, the misconceptions of the measles-mumps-rubella vaccine, and finally, what you can do to keep measles from "going viral."* Produced by James E Siegler and Erika Mejia. Music courtesy of Advent Chamber Orchestra, Coldnoise, Josh Woodward, Kevin McLeod, and Lee Roosevere. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Bester JC. Measles and measles vaccination: a review. JAMA Pediatr 2016;170(12):1209-15. PMID 27695849Bester JC. Not a matter of parental choice but of social justice obligation: children are owed measles vaccination. Bioethics 2018;32(9):611-19. PMID 30229958Campbell H, Andrews N, Brown KE, Miller E. Review of the effect of measles vaccination on the epidemiology of SSPE. Int J Epidemiol 2007;36(6):1334-48. PMID 18037676Fournet N, Mollema L, Ruijs WL, et al. Under-vaccinated groups in Europe and their beliefs, attitudes and reasons for non-vaccination; two systematic reviews. BMC Public Health 2018;18(1):196. PMID 29378545Maglione MA, Das L, Raaen L, et al. Safety of vaccines used for routine immunization of U.S. children: a systematic review. Pediatrics 2014;134(2):325-37. PMID 25086160Murch SH, Anthony A, Casson DH, et al. Retraction of an interpretation. Lancet 2004;363(9411):750. PMID 15016483Perry RT, Halsey NA. The clinical significance of measles: a review. J Infect Dis 2004;189 Suppl 1:S4-16. PMID 15106083Poland GA, Jacobson RM. The age-old struggle against the antivaccinationists. N Engl J Med 2011;364(2):97-9. PMID 21226573Trump's tweet:  https://twitter.com/realdonaldtrump/status/449525268529815552?lang=en  *Truth be told, measles claims the lives of 100,000 people around the globe every year. It has already gone viral. This was just a figure of speech. We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: May 16, 2019 It would be an understatement to say that endovascular thrombectomy has revolutionized acute stroke management. As of 2018, the American Heart Association recommends treatment up to 24 hours after time last seen normal for select patients. This week on the BrainWaves podcast, Dr. Tudor Jovin--PI for the DAWN and REVASCAT clinical trials--summarizes the history of thrombectomy trials and what it is about our current strategies that have breathed new life into a technique that has historically fizzled. Produced by James E Siegler and Jesse Thon. Music courtesy of Cuicuitte, Coldnoise, Medyn, Jon Watts, Lee Rosevere, and Mystery Mammal. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Campbell BC, Majoie CB, Albers GW, et al. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol 2019;18(1):46-55. Erratum in: Lancet Neurol 2019 Mar;18(3):e2. PMID 30413385Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387(10029):1723-31. PMID 26898852Gross BA, Jadhav AP, Jankowitz BT, Jovin TG. The ongoing revolution in thrombectomy: expanding inclusion criteria to larger cores. World Neurosurg 2018;120:393-94. PMID 30292027Heit JJ, Wintermark M. Perfusion computed tomography for the evaluation of acute ischemic stroke: strengths and pitfalls. Stroke 2016;47(4):1153-8. PMID 26965849Jadhav AP, Molyneaux BJ, Hill MD, Jovin TG. Care of the post-thrombectomy patient. Stroke 2018;49(11):2801-07. PMID 30355218Konstas AA, Goldmakher GV, Lee TY, Lev MH. Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke, part 2: technical implementations. AJNR Am J Neuroradiol 2009;30(5):885-92. PMID 19299489Nogueira RG, Jadhav AP, Haussen DC, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 2018;378(1):11-21. PMID 29129157Román LS, Menon BK, Blasco J, et al. Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol 2018;17(10):895-904. PMID 30264728 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: February 13, 2019 In the second half of our two-part series on complications of organ transplantation, Dr. Raj Dhar (Neurocritical Care, Washington University in St. Louis) discusses his experience managing the noninfectious complications of organ transplantation--from drug toxicities to multidisciplinary medical care. Produced by James E Siegler and Raj Dhar. Music by Steve Combs, Lee Rosevere, and Scott Holmes. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Dhar R, Young GB, Marotta P. Perioperative neurological complications after liver transplantation are best predicted by pre-transplant hepatic encephalopathy. Neurocrit Care 2008;8(2):253-8. PMID 17928960Dhar R. Neurologic complications of transplantation. Handb Clin Neurol 2017;141:545-572. PMID 28190435Mateen FJ, Dierkhising RA, Rabinstein AA, Van De Beek D, Wijdicks EF. Neurological complications following adult lung transplantation. Am J Transplant 2010;10(4):908-14. PMID 20121751Muñoz P, Valerio M, Palomo J, et al. Infectious and non-infectious neurologic complications in heart transplant recipients. Medicine (Baltimore) 2010;89(3):166-75. PMID 20453603Senzolo M, Ferronato C, Burra P. Neurologic complications after solid organ transplantation. Transpl Int 2009;22(3):269-78. PMID 19076332Wu Q, Marescaux C, Wolff V, et al. Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation. Eur Neurol 2010;64(3):169-77. PMID 20699617 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: December 20, 2018 This week, part 2 of our two-part primer on Huntington disease. Treatment. From tried-and-true therapies to the latest-and-greatest compounds being studied in clinical trials. Enjoy! Produced by James E Siegler and Steven Aradi. Music by Mike Durek, Jesse Spillane, Lee Rosevere, Jason Shaw, and Dr. Turtle. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Bates GP, Dorsey R, Gusella JF, et al. Huntington disease. Nat Rev Dis Primers 2015;1:15005. PMID 27188817Claassen DO, Carroll B, De Boer LM, et al. Indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease. J Clin Mov Disord 2017;4:3. PMID 28265459Paulsen JS, Nehl C, Hoth KF, et al. Depression and stages of Huntington's disease. J Neuropsychiatry Clin Neurosci 2005;17(4):496-502. PMID 16387989 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: December 6, 2018 You may be able to recognize chorea. But what does it make you think of besides Huntington disease? In this two-part series, we'll cover the clinical manifestations, differential diagnosis, and management of Huntington disease. In part 1, Dr. Travis Lewis (University of Pennsylvania) creates a framework for hyperkinetic movement disorders and Huntington disease. Part 2 will focus on the current and future therapeutics of this neurodegenerative condition. Produced by Travis Lewis and James E Siegler. Music by Azevedo Silva, Chris Zabriskie, Cullah, John Bartmann, and Nuno Adelaida. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Bates GP, Dorsey R, Gusella JF, et al. Huntington disease. Nat Rev Dis Primers 2015;1:15005. PMID 27188817Ghosh R, Tabrizi SJ. Huntington disease. Handb Clin Neurol 2018;147:255-78. PMID 29325616Reilmann R, Leavitt BR, Ross CA. Diagnostic criteria for Huntington's disease based on natural history. Mov Disord 2014;29(11):1335-41. PMID 25164527Walker RH. Chorea. Continuum (Minneap Minn) 2013;19(5 Movement Disorders):1242-63. PMID 24092289Wild EJ, Tabrizi SJ. The differential diagnosis of chorea. Pract Neurol 2007;7(6):360-73. PMID 18024776 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: November 22, 2018 Of the "reversible" causes of dementia, normal pressure hydrocephalus may be the most controversial. But there is something to be said about how surgical intervention alters the physiology of patients who present with gait impairment, ventriculomegaly, and normal CSF pressure. This week on the show, we discuss the clinical features and the controversy behind this diagnosis. Produced by James E Siegler. Music by Ghost, Jon Watts, Julie Maxwell, Komiku, and Kevin McLeod. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Gallia GL, Rigamonti D, Williams MA. The diagnosis and treatment of idiopathic normal pressure hydrocephalus. Nat Clin Pract Neurol 2006;2(7):375-81. PMID 16932588Kazui H, Miyajima M, Mori E, Ishikawa M; SINPHONI-2 Investigators. Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomised trial. Lancet Neurol 2015;14(6):585-94. PMID 25934242Klassen BT, Ahlskog JE. Normal pressure hydrocephalus: how often does the diagnosis hold water? Neurology 2011;77(12):1119-25. PMID 21849644Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM. Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 2005;57(3 Suppl):S4-16; discussion ii-v. PMID 16160425Williams MA, Relkin NR. Diagnosis and management of idiopathic normal-pressure hydrocephalus. Neurol Clin Pract 2013;3(5):375-85. PMID 24175154 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: October 25, 2018 Every time you order an MRI with contrast, you should think to yourself, "Why do I need contrast?" Then, "If I need contrast, what are the risks?" This week's show is all about the risks of routine neuroimaging. Produced by James E Siegler. Music by Little Glass Men, Loyalty Freak Music, and Kevin McLeod. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES McDonald RJ, McDonald JS, Kallmes DF, et al. Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology 2015;275(3):772-82. PMID 25742194Pullicino R, Radon M, Biswas S, Bhojak M, Das K. A review of the current evidence on gadolinium deposition in the brain. Clin Neuroradiol 2018;28(2):159-69. PMID 29523896Rogosnitzky M, Branch S. Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms. Biometals 2016;29(3):365-76. PMID 27053146 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: November 8, 2018 A patient comes into the emergency department. They've got a headache. You get some basic labs, a chest x-ray, and a CT scan. And then you get a drug screen. But does this information even help you? And could it hurt the patient? This week on the BrainWaves podcast, Dr. Emily Rosenthal shares her experience with Dr. Kelley Humbert on the ethics of toxicology "screening" and how she manages patients with a substance use disorder. Produced by Emily Rosenthal, Kelley Humbert, and Jim Siegler. Music by Montplaisir, Lee Rosevere, and Kevin McLeod. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @brainwavesaudio for the latest updates to the podcast. REFERENCES Bates GP, Dorsey R, Gusella JF, et al. Huntington disease. Nat Rev Dis Primers 2015;1:15005. PMID 27188817Eisen JS, Sivilotti ML, Boyd KU, Barton DG, Fortier CJ, Collier CP. Screening urine for drugs of abuse in the emergency department: do test results affect physicians' patient care decisions? CJEM 2004;6(2):104-11. PMID 17433159Jones HE, Kaltenbach K, Heil SH, et al. Neonatal abstinence syndrome after methadone or buprenorphine exposure. N Engl J Med 2010;363(24):2320-31. PMID 21142534Lager PS, Attema-de Jonge ME, Gorzeman MP, Kerkvliet LE, Franssen EJ. Clinical value of drugs of abuse point of care testing in an emergency department setting. Toxicol Rep 2017;5:12-17. PMID 29270362Silver B, Miller D, Jankowski M, et al. Urine toxicology screening in an urban stroke and TIA population. Neurology 2013;80(18):1702-9. PMID 23596074Smith PC, Schmidt SM, Allensworth-Davies D, Saitz R. A single-question screening test for drug use in primary care. Arch Intern Med 2010;170(13):1155-60. PMID 20625025Tenenbein M. Do you really need that emergency drug screen? Clin Toxicol (Phila) 2009;47(4):286-91. PMID 19514875 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: October 11, 2018 As the name suggests, "evidence-based medicine" is dependent on published evidence to support our clinical practice and medical decision-making. Implicit in this is the notion that all published evidence reflects the truth that underlies the biology, pathophysiology, and pharmacology of our health. This is not the case. Clinical research and published findings can be extremely limited, and what you read in Lancet and NEJM should be interpreted with caution. In this week's episode of the "I wonder" series, where Jim Siegler speaks with Ali Hamedani on various topics in medicine and neurology, the speakers review the major biases inherent to the practice and interpretation of clinical research. Produced by James E Siegler. Music by Jahzzar, Kai Engel, and Lee Rosevere. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. REFERENCES Anonymous. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988;2(8607):349-60. PMID 2899772Kazui H, Miyajima M, Mori E, Ishikawa M; SINPHONI-2 Investigators. Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomised trial. Lancet Neurol 2015;14(6):585-94. PMID 25934242Montalban X, Hauser SL, Kappos L, et al. Ocrelizumab versus placebo in primary progressive multiple sclerosis. N Engl J Med 2017;376(3):209-20. PMID 28002688Smith GC, Pell JP. Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials. BMJ 2003;327(7429):1459-61. PMID 14684649 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: August 2, 2018 How visual information transforms from pixels into people is more complex than dots becoming lines, lines becoming shapes, and shapes becoming faces. Your brain makes assumptions about all kinds of sensory information--even without you knowing it. Dr. Geoffrey Aguirre, a neuroscientist who specializes in vision processing, explains how we know what we can't really explain. Produced by James E Siegler and Geoff Aguirre. Music by Cullah, Jon Watts, Lovira, Loyalty Freak Music, and Scott Holmes. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. REFERENCES Psalta L, Young AW, Thompson P, Andrews TJ. The Thatcher illusion reveals orientation dependence in brain regions involved in processing facial expressions. Psychol Sci 2014;25(1):128-36. PMID 24264941Thompson P. Margaret Thatcher: a new illusion. Perception 1980;9(4):483-4. PMID 6999452 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: September 27, 2018 When is eye pain an ophthalmological issue, and when is it a neurologic issue? This week, neuro-ophthalmologist and glaucoma specialist Dr. Ahmara Ross simplifies ocular pain for the day-to-day neurologist. Produced by James E Siegler and Ahmara Ross. Music by Yan Terrien, Unheard Music Concepts, Steve Combs, and Scott Holmes. Sound effects by Mike Koenig, Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @BrainWave saudio for the latest updates to the podcast. REFERENCES Fiore DC, Pasternak AV, Radwan RM. Pain in the quiet (not red) eye. Am Fam Physician 2010;82(1):69-73. PMID 20590074Friedman DI. The eye and headache. Continuum (Minneap Minn) 2015;21(4 Headache):1109-17. PMID 26252594Lee AG, Al-Zubidi N, Beaver HA, Brazis PW. An update on eye pain for the neurologist. Neurol Clin 2014;32(2):489-505. PMID 24703541Waldman CW, Waldman SD, Waldman RA. A practical approach to ocular pain for the non-ophthalmologist. Pain Manag 2014;4(6):413-26. PMID 25494693 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

Mandi and John put on sweat inducing leather and answer every unknown number for 2023's SUITABLE FLESH. Can they body swap their way through reverse camera crushings, hypno-stabbing, and awkward admissions from husbands? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg SUITABLE FLESH (2023) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi grab their cellphone necklaces and start memorizing maps for 2006's SILENT HILL. Can they barbwire crawl their way through acid spitting tube men, EZ-peel Anna, and the crispification of Cybil? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg SILENT HILL (2006) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John grab their "chicken" cookies and massively rewrite Roman Mythology for 2020's CUPID. Can we valentine our way through cutthroat card throwing, one dozen throat roses and the evil that is... THE POPULAR GIRL? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg CUPID (2020) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi prepare their most potent poking sticks and grab change for the pay toilets while watching 1991's ALLIGATOR 2: THE MUTATION. Can they wade their way through villainous land developing genetics lab owners, pathetic politicians and the most antisocial alligator on the west coast? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg ALLIGATOR 2: THE MUTATION (1991) Trailer. Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

ESat3AM finishes it's look at anthology horror with GUILLERMO DEL TORO'S CABINET OF CURIOSITIES S1E5: "PICKMAN'S MODEL". Will the sight of spooky art drive them to the brink of madness? or is it just the accents? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

ESat3AM continues it's look at anthology horror with ARE YOU AFRAID OF THE DARK: S2E9 "THE TALE OF MIDNIGHT MADNESS" Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own

ESat3AM continues it's look at anthology horror with TALES FROM THE CRYPT S6E1: LET THE PUNISHMENT FIT THE CRIME. Can we talk our way out of this or are we to stuck out in the sticks? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

ESat3am starts out a month long look at anthology horror from the small screen with CREEPSHOW SEASON 1, EPISODE 6: SKINCRAWLERS. Can they slide their way through Chunk or Hunk, taco snobbery or eyeball wigglers? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John start the New Year off right with 2023's COCAINE BEAR. Can they snort their way through lines of laughably bad park punks, abysmally inaccurate park rangers, and rampaging ursine hopped up on booger sugar? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for COCAINE BEAR (2023) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi bake a fresh batch of skin cookies and ready the old snatching tent for 2017's MOTHER KRAMPUS. Can they force push their way through convoluted murder plots, Christmas light sticks, and neck candy canes? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for MOTHER KRAMPUS (2017) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John ready their fingers for tiny door opening and do their best not to feed their dog a car for 2021's THE ADVENT CALENDAR. Can they ICH their way through stolen little blue pills of MURDER, sympathetic truck crushing, and French rules for surviving a horror movie? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for THE ADVENT CALENDER (2021) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi put on their track suits and dream of better movies while suffering through 2023's IT'S A WONDERFUL KNIFE. Can they drag their feet through bland characters with vaguely defined connections, Costuming and Actors who deserved to be in a better movie, and some kind of drone plot point that comes out of nowhere and makes no sense? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for IT'S A WONDERFUL KNIFE (2023) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John grab their train robbing bandannas and open every suspicious trunk we can find for 2020's THE PALE DOOR. Can we old-school gunfight our way out of burned witch prostitutes, sudden bird emesis and the shear awesomeness that is Dodd? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for EPISODE 210: THE PALE DOOR (2020) (2020) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.  Originally released: December 27, 2018 As I'm sitting in a coffee shop in upstate New York this holiday season, procrastinating on the various papers that need writing, bills that need paying, and Christmas cards that need writing, I can't help but feel comforted by the warm relief of a cup of coffee. The rich aroma and jolting heat, which come with the promise of productivity. There's nothing like it. So before resigning to my post-holiday to-do list, I thought I would start the day off re-mastering a prior show we put out in 2017 on the neuroscience behind your morning mocha. Enjoy! Produced by James E Siegler. Music by Andy Cohen and Little Glass Men. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @BrainWavesaudio for the latest updates to the podcast. REFERENCES Ferré S. An update on the mechanisms of the psychostimulant effects of caffeine. J Neurochem 2008;105(4):1067-79. PMID 18088379Martín ED, Buño W. Caffeine-mediated presynaptic long-term potentiation in hippocampal CA1 pyramidal neurons. J Neurophysiol 2003;89(6):3029-38. PMID 12783948Nawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A, Feeley M. Effects of caffeine on human health. Food Addit Contam 2003;20(1):1-30. PMID 12519715Park CA, Kang CK, Son YD, et al. The effects of caffeine ingestion on cortical areas: functional imaging study. Magn Reson Imaging 2014;32(4):366-71. PMID 24512799Pelchovitz DJ, Goldberger JJ. Caffeine and cardiac arrhythmias: a review of the evidence. Am J Med 2011;124(4):284-9. PMID 21435415Ribeiro JA, Sebastião AM. Caffeine and adenosine. J Alzheimers Dis 2010;20 Suppl 1:S3-15. PMID 20164566  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: March 14, 2019 In 2016, we heard the results of the MGTX trial--a pivotal investigation that demonstrated the efficacy of thymectomy for select patients with non-thymomatous myasthenia gravis. This spring, we saw the long-term follow-up data from the MGTX investigators. In this week's re-run, we summarize these data, critique it, and reflect on how it may change clinical practice. Produced by James E Siegler. Music courtesy of Scott Holmes and Lee Rosevere. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @BrainWaves audio for the latest updates to the podcast. REFERENCES Blalock A, Harvey AM, Ford FR, Lilienthal JL. The treatment of myasthenia gravis by removal of the thymus gland. JAMA 1941;117:1529-33.Oosterhuis HJ. Observations of the natural history of myasthenia gravis and the effect of thymectomy. Ann N Y Acad Sci 1981;377:678-90. PMID 6951492Wolfe GI, Kaminski HJ, Aban IB, et al. Randomized trial of thymectomy in myasthenia gravis. N Engl J Med 2016;375(6):511-22. Erratum in: N Engl J Med 2017;376(21):2097. [Dosage error in article text]. PMID 27509100Wolfe GI, Kaminski HJ, Aban IB, et al. Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial. Lancet Neurol 2019;18(3):259-68. PMID 30692052  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

John and Mandi grab their finest train attire and ignore all telegrams for 1989's BEYOND THE DOOR 3. Can they locomote their way through pancake makeup'd villagers, tilting crossing signs and a train so bloodthirsty it'll circle back and kill you in the middle of a lake? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for BEYOND THE DOOR 3 (1989) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John anoint themselves with oil and hop on to their Vespas for 2023's THE POPE'S EXORCIST. Can we pray our way through closet demon beat downs, guilt ridden cardinal eating, or the books being good? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for THE POPE'S EXORCIST (2023) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: October 14, 2018 There is nothing mysterious about the chemistry of the cerebrospinal fluid. Cells. Protein. Glucose. But the interplay of these unique components can give you incredible insight into the state of the central nervous system. This week, we revisit a prior episode where Dr. Mike Rubenstein reviews his approach to interpreting CSF results. And then we have an update at the end regarding recent advances in CSF analysis. Produced by James E Siegler and Michael Rubenstein. Music by Steve Combs. Sound effects by Mike Koenig and Daniel Simion. Voiceover by Patrick Green (German). BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. If you like what you hear, let us know, and rate the show! REFERENCES Deisenhammer F, Bartos A, Egg R, et al. Guidelines on routine cerebrospinal fluid analysis. Report from an EFNS task force. Eur J Neurol 2006;13(9):913-22. PMID 16930354Frederiks JA, Koehler PJ. The first lumbar puncture. J Hist Neurosci 1997;6(2):147-53. PMID 11619518Messacar K, Schreiner TL, Van Haren K, et al. Acute flaccid myelitis: a clinical review of US cases 2012-2015. Ann Neurol 2016;80(3):326-38. PMID 27422805Nagel MA, Cohrs RJ, Mahalingam R, et al. The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology 2008;70(11):853-60. PMID 18332343Seehusen DA, Reeves MM, Fomin DA. Cerebrospinal fluid analysis. Am Fam Physician 2003;68(6):1103-8. PMID 14524396Shah KH, Edlow JA. Distinguishing traumatic lumbar puncture from true subarachnoid hemorrhage. J Emerg Med 2002;23(1):67-74. PMID 12217474  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

ESat3AM returns to find a popup where a podcast should be in 2022's SPIRIT HALLOWEEN: THE MOVIE. Can we haunt our way through murderous animatronics, modded foam dart guns and a surprisingly well acted tale fit for the whole family? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for SPIRIT HALLOWEEN: THE MOVIE (2022) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021. Originally released: June 20, 2019 You might think George Clooney gets his devilishly handsome smile from well-polished genes or a long history of acting lessons. As it turns out, he has mild residual weakness from a remote Bell palsy. In this week's installment of the BrainWaves podcast, we've got even more factoids about the facial nerve as we revisit a prior show that originally aired in January 2017. We've touched up the audio a bit, so get comfortable and grab a pen; you may want to take notes on this one. Produced by James E Siegler. Music courtesy of Marcos H. Bolanos, Jon Watts & Lee Rosevere. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter @BrainWaves audio for the latest updates to the podcast. REFERENCES Gaio E, Marioni G, de Filippis C, Tregnaghi A, Caltran S, Staffieri A. Facial nerve paralysis secondary to acute otitis media in infants and children. J Paediatr Child Health 2004;40(8):483-6. PMID 15265194Gilden DH. Clinical practice. Bell's Palsy. N Engl J Med 2004;351(13):1323-31. PMID xxxxxxxHabel A. Ueber Fortbestehen von Tic convulsif bei gleichseitiger Hemiplegie. Deutsche Med Wchnschr 1898;24:189.Sweeney CJ, Gilden DH. Ramsay Hunt syndrome. J Neurol Neurosurg Psychiatry 2001;71(2):149-54. PMID 11459884  We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

John and Mandi ready their axes and watch out for sharp stones in 2020's BOYS FROM COUNTY HELL. Can they dodge rampaging bulls that aren't actually bulls, drunken hemophagic security guards and William's mom messing up the plan? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for BOYS FROM COUNTY HELL (2020) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John grab their craziest straws and aim for the giant red nose for 1988's KILLER KLOWNS FROM OUTER SPACE! Can they honk their way through homely homicidal harlequins, furiously fist fighting funnymen and some kind of weird popcorn clown eggs? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for KILLER KLOWNS FROM OUTER SPACE (1988) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi sharpen their axes and check their sleeping bags on the floor for spiders with 2022's A TOWN FULL OF GHOSTS. Can they get a return on investment while dealing with Bert-I.-Growing wasp nests, ghost whiskey and the maze that really should've been torn down on the first day? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for A TOWN FULL OF GHOSTS (2022) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

John and Mandi walk on to death row and check most of their weapons at the door for 2023's NEFARIOUS. Can they converse their way through demonic mind games, cruel denials of last meals and realistic finger snapping all while having a very deep and sometimes disturbing discussion on theology? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for NEFARIOUS (2023) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.

Mandi and John buy prepackaged foods and water purifiers for 1987's THE CURSE. Can they deal with Evil Craven and his ominous banjo, melty mom and the iron hands of Farmer Crane? Get more of us! Email: esat3am@gmail.com/ Twitter: @ESAT3AM Facebook: http://www.facebook.com/ESAT3AM/ Website: https://esat3am.com/ Leave us a voicemail: https://anchor.fm/everythings-scary-at-3-am Credits Photo by Gabriel- @natural https://unsplash.com/photos/qUcNy_NSeoo Opening music: "Ghost Stories" by Alex Lisi https://www.youtube.com/channel/UC2Wkg85Gabk3DkC14DdUohg Trailer for THE CURSE (1987) Additional audio from: Daniel Simion http://soundbible.com/2170-Clock-Chimes-4x.html All opinions are our own.