Podcasts about Organ transplantation

How do you lead as a woman of colour in surgery? Join us as Hannah Maple sits down with Evelyn Mensah and Sala Abdalla to discuss the experiences of women of colour in surgery from personal stories, the impact of racism, and theirjourneys towards leadership. We delve into the importance of leadership, offering advice for aspiring women surgeons, and emphasise the power of visibility and support. Don't miss this compelling conversation that challenges and inspires!Guest: Evelyn MensahEvelyn (Evie) Mensah, Consultant Ophthalmologist and WRES Expert at London North West University Healthcare NHS Trust is part of the London and Medical WRES Strategy Groups. Evie leads ophthalmology and anti-racism initiatives globally, aiming for equitable healthcare. She championsinstitutional courage. In October 2024, Evie was appointed as the President for the Ophthalmology section of the Royal Society of Medicine. During her two year tenure she hopes to foster closer relationships between ophthalmologists andthe wider multi-disciplinary team.Guest: Sala AbdallaDr Sala Abdalla is a Consultant General, Emergency and Upper Gastrointestinal (GI) Surgeon at the London North West University Healthcare Trust. Dr Abdalla is the author of numerous publications in the field of surgery and surgical education including two textbooks; 'A History of Surgery' which she co-authored with Harold Ellis CBE FRCS, showcasing her dedication to exploring the rich history of surgical practices across the globe, and 'Cracking the general surgical interviews for ST3', which serves as a valuable preparatory resource for aspiring surgeons. DrAbdalla is deeply invested in advancing global access to surgical care. She is the founder and director of a surgical charity called Operation International UK which has close collaboration with the Royal College of Surgeons of England. Her charity delivers free surgical care and education tounderserved communities around the world. She has received two national awards for her charitable work and cites her charity as one of her proudest achievements. Hosted by: Hannah MapleHannah Maple is a Consultant Transplant and Dialysis Access surgeon based at Guys and St Thomas' NHS Foundation Trust and the lead for simulation research. Hannah is the past-Chair of the Ethical, Legal and Psychosocial aspects of Transplantation section (ELPAT) of the European Society of Organ Transplantation and completed the Emerging Leaders Fellowship, awarded by the Royal College of Surgeons of England, in 2023. Resources·       Watch Evelyn Mensah's inaugural address when appointed as the President for the Ophthalmology Section of the Royal Society of Medicine: OPT01 - Equitable, Diverse and Inclusive Ophthalmology through the Eyes of a Geordie Ghanaian - Zoom·       How can I be antiracist·       Cracking the General Surgical Interviews for ST3·       The Kennedy Review·       Medical Workforce Race Equality Standard in England·       GMC data supporting the Medical Workforce Race Equality Standard in England·       NHS Workforce Race Equality StandardNews & Updates from RCS England· RCS England is celebrating the 10-year anniversary of the Emerging Leaders programme. Applications open on 15 May and closes on 1 September 2025.· RCS England: Diversity, Equity & Inclusion / Interested in getting involved or supporting our work? Please contact: diversity@rcseng.ac.uk· The 2025 UK surgical workforce census is now open. It's quick, confidential and crucial. Your voice helps us push for real change where it matters most, from tackling workforce shortages to improving wellbeing and training. Take the census now: https://www.rcseng.ac.uk/standards-and-research/surgical-workforce-census/?utm_source=Digital&utm_medium=TheTheatre&utm_campaign=Census2025Produced by: Andrea PearsonWe would love to hear from you so please do reach out to us on social media, or email us at podcasts@rcseng.ac.uk

Jaya Tiwari, Senior Vice President of Clinical and Regulatory Affairs at XVIVO, which is focused on improving organ preservation for transplantation. Current organ preservation methods using ice coolers limit the time and distance organs can be transported.  XVIVO's perfusion technology can significantly extend the preservation time of hearts, kidneys, livers, and lungs, providing hospitals and transplant centers access to more viable organs. The company is passionate about increasing organ availability to give more patients access to life-saving transplants. Jaya explains, "I take it back to 1967 when the first heart transplant was performed in Cape Town, and the way that the heart was preserved and transported in essentially an ice box. The standard of care for the preservation of organs is still an ice or an ice cooler with ice. So, this decreases metabolic activities. So, to try to preserve the organs so that you can get them from the donor to the recipient, the problem is that the organs are not viable for a very long time, and they start to degrade very quickly. That really limits the amount of time that the organs can be on ice, transported from the donor to the recipient hospital. Because of that logistical complexity, a lot of organs are ultimately not transplanted." "There have been some preclinical studies that we've done that have shown viability of the heart tissue for up to 24 hours. But what I think is probably the most remarkable example that we've seen is that the universities in Paris have put together something called an investigator-initiated study, where they actually were able to transport a donor heart from the French West Indies to Paris for transplant. That was about 12 hours that the heart was in transport and using the device. So that's remarkable because that essentially tripled the standard preservation time for hearts. Now, in the US, we have a clinical trial where we're currently seeking approval from the FDA that it's safe and effective to use this device for up to 12 hours." #XVIVO #HealthcareInnovation #LifeSavingTechnology #PatientOutcomes #OrganTransplantation #OrganTransplants xvivogroup.com Download the transcript here

Jaya Tiwari, Senior Vice President of Clinical and Regulatory Affairs at XVIVO, which is focused on improving organ preservation for transplantation. Current organ preservation methods using ice coolers limit the time and distance organs can be transported.  XVIVO's perfusion technology can significantly extend the preservation time of hearts, kidneys, livers, and lungs, providing hospitals and transplant centers access to more viable organs. The company is passionate about increasing organ availability to give more patients access to life-saving transplants. Jaya explains, "I take it back to 1967 when the first heart transplant was performed in Cape Town, and the way that the heart was preserved and transported in essentially an ice box. The standard of care for the preservation of organs is still an ice or an ice cooler with ice. So, this decreases metabolic activities. So, to try to preserve the organs so that you can get them from the donor to the recipient, the problem is that the organs are not viable for a very long time, and they start to degrade very quickly. That really limits the amount of time that the organs can be on ice, transported from the donor to the recipient hospital. Because of that logistical complexity, a lot of organs are ultimately not transplanted." "There have been some preclinical studies that we've done that have shown viability of the heart tissue for up to 24 hours. But what I think is probably the most remarkable example that we've seen is that the universities in Paris have put together something called an investigator-initiated study, where they actually were able to transport a donor heart from the French West Indies to Paris for transplant. That was about 12 hours that the heart was in transport and using the device. So that's remarkable because that essentially tripled the standard preservation time for hearts. Now, in the US, we have a clinical trial where we're currently seeking approval from the FDA that it's safe and effective to use this device for up to 12 hours." #XVIVO #HealthcareInnovation #LifeSavingTechnology #PatientOutcomes #OrganTransplantation #OrganTransplants xvivogroup.com Listen to the podcast here

Host: Darryl S. Chutka, M.D. Guest: Julie K. Heimbach, M.D. In 2024, over 48,000 organ transplants were performed in the U.S., representing an increase over the number performed the year before. There was also an increase in the number of transplants performed internationally, offering hope to patients worldwide with organ failure. Significant advancements have been made in the field of organ transplantation, and this is responsible for the success of the organ transplantation program. What are some of the major milestones that have taken place since the initial organ transplant? How has technology improved the success of an organ transplanted? What role will xenotransplantation, or transplantation of animal organs play in the future? These are some of the questions I'll be asking my guest, Julie K. Heimbach, M.D., transplant surgeon and director of the Transplant Center at the Mayo Clinic. The topic for this podcast is “What's New in Transplant Surgery?” Learn more about this Transplant Series:  Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development Connect with Mayo Clinic's Transplant Center online at https://mayoclinic.org/transplant or on X @MayoTransplant. To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation. Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Darryl S. Chutka, M.D. Guest: C. Burcin Taner, M.D. Recently, the criteria for organ donors have expanded in order to address the increasing difference between the number of available organs and the demand for transplants. Advancements in medical technology, a better understanding of transplant immunology, and the improvement of transplant surgery techniques have allowed for the inclusion of a greater pool of donors with various health conditions, which excluded them as donors in the past. Understanding the delicate balance between expanding the criteria for transplantation and maintaining a high quality of life for the recipients has been important in advancing the field of organ transplantation. The topic for this podcast is “Expanded Donor Criteria for Organ Transplantation” and my guest is C. Burcin Taner, M.D., Professor of Surgery and Chair of the Department of Transplantation at the Florida campus of the Mayo Clinic. Learn more about our Transplant Series:  Mayo Clinic Talks: Donate Life: Transplantation Series | Mayo Clinic School of Continuous Professional Development Connect with Mayo Clinic's Transplant Center online at https://mayoclinic.org/transplant or on Twitter @MayoTransplant To learn more and register to be an organ donor please visit https://careinfo.mayoclinic.org/organ-donation. Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “The effect of rewarming ischemia on tissue transcriptome and metabolome signatures: A clinical observational study in lung transplantation.”   Dr. Van Slambrouck is a general surgeon who's just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium.   The episode explores:  How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literature prepared the team to track and evaluate it Clinical strategies to reduce RIT and directly address molecular changes   For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Those involved in the pulmonary vascular disease space should tune in again later this month for a study on the safety and efficacy of riociguat in patients with PAH.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

February is American Heart Month, and in light of that, we're bringing back an episode about a group here at Stanford Engineering that's developing 3D printing methods for human tissues and organs, a process known as bioprinting. Motivated in part by the critical need for heart transplants, Mark Skylar-Scott and his team are specifically working to bioprint tissues of the human heart. It may sound like science fiction, but it's actually just another example of the groundbreaking research we do here. We hope you'll take another listen and be inspired by the possibilities.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Mark A. Skylar-ScottMark's Lab: The Skylar-Scott Lab | Stanford MedicineConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest, Mark Skylar-Scott, a professor of bioengineering at Stanford University.(00:02:06) What is Bioprinting?The role of cells and biopolymers in printing functional biological structures.(00:03:31) Bioprinting a HeartThe potential of printing organs on demand, especially heart tissue.(00:04:38) Obtaining Cells for BioprintingUsing stem cells derived from the patient's own cells to create heart tissue.(00:06:29) Creating Multiple Cell Types for the HeartThe challenge of printing eleven different heart cell types with precision.(00:08:50) The Scaffold for 3D PrintingThe support material used in 3D printing and how it's later removed.(00:10:10) Cell Migration and Organ FormationHow cells organize themselves to form functional heart tissue.(00:12:08) Growing a Full-Sized HeartWhether they're printing full-sized hearts or starting with smaller organs.(00:13:34) Avoiding Overgrowth RisksThe role of bioreactors in shaping the early stages of the organ.(00:14:57) Scaling Up Cell ProductionThe need to generate massive numbers of cells for experimentation.(00:18:32) The Challenge of VascularizationCreating a blood vessel network to supply oxygen and nutrients.(00:22:35) Ethical Considerations in BioprintingConsent, stem cell sourcing, and the broader ethical landscape.(00:26:04) The Timeline for Bioprinted OrgansThe long timeline for bioprinted organs to reach clinical use.(00:27:24) The State of the Field & CollaborationThe collaborative, competitive biofabrication field and its rapid progress.(00:28:20) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jonathan E. Williams, MD, to discuss the paper, “Ex-Vivo Lung Perfusion: National Trends and Post-Transplant Outcomes.” Dr. Williams is a general surgery resident at the University of Michigan in Ann Arbor, with work focusing on contemporary lung preservation strategies, perfusion techniques, and particularly, EVLP. The episode explores: How the study explores the theory that EVLP use may increase transplant volumes Preserving data quality and other study limitations How to work in fields of study that sometimes yield as many questions as answers For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. Those on heart transplant teams should tune in again later this month for a study on sympathetic reinnervation in cardiac transplant recipients. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

JHLT: The Podcast returns with a year-end recap of 2024. Each Digital Media Editor shares one of their favorite studies from JHLT in 2024 for a quick recap of last year's excellent science in advanced heart and lung disease. Studies featured: ·         Cardiac magnetic resonance assessment of acute rejection and cardiac allograft vasculopathy in pediatric heart transplant Kikano, Sandra et al. JHLT May 2024 5(43):745-754 ·         A modular simulation framework for organ allocation Rose, Johnie et al. JHLT Aug 2024 8(43):1326-1335. ·         HeartMate 3 Snoopy: Noninvasive cardiovascular diagnosis of patients with fully magnetically levitated blood pumps during echocardiographic speed ramp tests and Valsalva maneuvers Schlöglhofer, Thomas et al. JHLT Feb 2024 2(43):251-260. ·         Factors associated with acute limb ischemia in cardiogenic shock and downstream clinical outcomes: Insights from the Cardiogenic Shock Working Group Kochar, Ajar et al. JHLT Nov 2024 11(43):1846-1856.   For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

In this Leveling Up episode of the PRS Global Open Deep Cuts Podcast, Dr. Azari discusses the nuances of bread and butter hand surgery procedures like carpal tunnel and Dupuytren's fasciectomies, his approach to providing trainees with gradually increasing levels of responsibility and autonomy, how he builds rapport with patients and personalizes his approach to each patient's needs and goals, why it's sometimes important to go against your instincts when dealing with problematic patients, his interest in and lessons learned from hand transplantation, and why patients can be a bit like circling helicopters.   Dr. Kodi Azari is a Professor of Orthopaedic Surgery and Plastic Surgery at UCLA Medical center in Los Angeles, California. He serves as the Chief of Reconstructive Transplantation as well as the Medical Co-Director of Operation Mend which is a UCLA program aimed at providing complex reconstructive surgery for wounded service members injured in Operations Enduring Freedom and Iraqi Freedom.   Dr. Azari completed General Surgery and Plastic Surgery training at the University of Pittsburgh Medical Center, a Tissue Engineering Fellowship at Carnegie Mellon University, and a Hand and Microsurgery Fellowship at UCLA. He has been one of the lead surgeons on 7 hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States.   He is a founding member of the American Society for Reconstructive Transplantation, and has served as an Associate Editor for the “Annals of Plastic Surgery,” Guest Editor for “Current Concepts in Organ Transplantation,” and contributing editor for the “Yearbook of Hand and Upper Limb Surgery.”   Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas.   #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

In this compelling episode of Kidney Transplant Conversations, Valen Keefer joins us to share her extraordinary journey through the world of organ transplantation. From a young age, Valen faced the challenges of living with a chronic illness, navigating the complexities of kidney and liver transplants. Her story is one of resilience, advocacy, and empowerment. Valen discusses her impactful docuseries, "Letters of Hope," which chronicles her experiences and serves as a resource for both patients and caregivers. She highlights the importance of finding one's voice in the healthcare journey and the vital role caregivers play in the process. As a passionate advocate, Valen talks about her mission to educate and inspire others, emphasizing the significance of organ donation and the need for accurate portrayals in media. Her upcoming recognition at the Donate Life Hollywood Inspire Awards underscores her commitment to raising awareness and fostering understanding. Tune in to learn more about Valen's remarkable story, the power of community, and how individuals can live a full life post-transplant. Discover how her experiences are helping to shape a brighter future for those in the transplant community. (c) Project Advocacy 2022-2024 Link: Letter of Hope Docuseries https://valenkeefer.com/letters-of-hope-docuseries  Link: Valen Keefer Website https://valenkeefer.com/ 

On this episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the October issue of JHLT, entitled “Donor to recipient age matching in lung transplantation: A European experience.” Senior author Andrew Fisher, FRCP, PhD joins the podcast to discuss the paper. You'll hear about: European practices in lung transplantation and the donor population Main findings and takeaways How age disparities in donor matching affect outcomes Extended criteria for older donors For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. If you haven't yet tuned in for the first October episode of the podcast, scroll back in the episode history for the latest ISHLT guideline on the evaluation and care of cardiac transplant candidates. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

In this special episode of JHLT: The Podcast, the Digital Media Editors connect with Joseph Rogers, MD, the new Editor-in-Chief of JHLT. In the conversation, Dr. Rogers shares more about his vision for the Journal, how he plans to tackle the challenges and opportunities facing the publication, and a little about his life both inside and outside of medicine. In addition to being the new Editor-in-Chief, Dr. Rogers is the President and CEO of the Texas Heart Institute in Houston, a past president of the ISHLT, and a prolific contributor to the field of heart and lung transplantation. For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

In this Join the Docs episode, the ever-charismatic Professor Jonathan Sackier and the delightfully witty Doctor Nigel Guest dive headfirst into a rollicking discussion about the medical marvels of various body parts. Picture this: a room filled with laughter as they dissect (pun intended) the critical importance of blood and organ donation, weaving in tales of heroic donors and miraculous recoveries.So, what are the ethics of organ donation? The Docs debate the merits of donating your earthly vessel to science versus becoming a mummy in a museum. And just when you think it can't get any more fascinating, they plunge into the world of umbilical cord blood and placenta, painting vivid pictures of these often-overlooked biological treasures. It's a labour of love, quite literally!Hold onto your seats as the discussion gets a bit cheeky with sperm and eggs, where The Docs' playful banter about the birds and the bees will have you in stitches. And just when you think the episode has reached its peak, they introduce the pièce de résistance: faecal transplants. Yes, you heard that right. The episode delves into the surprisingly sophisticated science of poop, sharing stories that are both mind-blowing and side-splitting. What have we learned from the past? The Docs entertain listeners with captivating tales of ancient medical practices, ranging from the bizarre to the revolutionary, offering insights into just how much progress we've made in understanding and treating the human body.The episode also features a segment on the future of medicine, where the potential advancements that could revolutionise healthcare are brought to attention. From the promise of regenerative medicine and stem cell therapy to the ethical implications of genetic engineering, the discussion is as thought-provoking as it is entertaining.So, whether you're a medical professional, a curious layperson, or simply someone who enjoys a good laugh, this episode of "Join the Docs" promises to be a captivating and enlightening experience. Tune in and join the conversation, because when it comes to understanding the human body, It's bound to be just what the doctor ordered!—--DISCLAIMER: The views and opinions expressed on Join the Docs are those of Dr. Nigel Guest, Jonathan Sackier and other people on our show. Be aware that Join the Docs is not intended to be medical advice, it is for information and entertainment purposes only - please, always take any health concerns to your doctor or other healthcare provider. We respect the privacy of patients and never identify individuals unless they have consented. We may change details, dates, place names and so on to protect privacy. Listening to Join the Docs, interacting on our social media, emailing or writing to us does not establish a doctor patient relationship.To Contact Us: For a deeper dive on this episode's issue, merchandise and exclusive content, head to www.jointhedocs.comFollow us on youtube.com/JoinTheDocs Follow us on instgram.com/JoinTheDocsFollow us on tiktok.com/JoinTheDocsFollow us on: facebok.com/JoinTheDocsFollow us on: x.com/JoinTheDocs

The United Launch Alliance's Atlas V carried out its final National Security Space Launch (NSSL). SpaceX is reportedly in talks with US and Australian officials to land and recover one of its Starship rockets off Australia's coast. Redwire plans to culture bioprinted vascularized liver tissue constructs on the ISS to determine if liver cells bioprinted on Earth can properly form functioning blood vessels in microgravity, and more. Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our weekly intelligence roundup, Signals and Space, and you'll never miss a beat. And be sure to follow T-Minus on LinkedIn and Instagram. T-Minus Guest Our guest today is Caroline Schumacher, CEO of the Astronaut Scholarship Foundation (ASF). You can connect with Caroline on LinkedIn, and learn more about ASF on their website. Selected Reading Atlas V rocket launches final national security mission- Space Exclusive: SpaceX in talks to land and recover Starship rocket off Australia's coast- Reuters Boeing Wins Space Mission Contracts Owing To Its 'Armies Of Lobbyists,' Says SpaceX CEO Elon Musk Amid Starliner Return Delay Redwire to Test 3D Bioprinted Liver Tissue in Space, Reinforcing the Company's Focus on Transforming the Future of Organ Transplantation on Earth- Business Wire A wearable device to track, analyse and predict astronaut health - iLAuNCH Equatorial Space secures pre-Series A round led by Farquhar VC with participation by Paspalis Delivery of MIRA II and MIRA III airframe structures Viasat Introduces Wearable Secure Wireless Hub for Advanced Network and Edge Communications NASA, JAXA Bounce Laser Beam Between Moon's Surface and Lunar Orbit T-Minus Crew Survey We want to hear from you! Please complete our 4 question survey. It'll help us get better and deliver you the most mission-critical space intel every day. Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at space@n2k.com to request more info. Want to join us for an interview? Please send your pitch to space-editor@n2k.com and include your name, affiliation, and topic proposal. T-Minus is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

Kennedy Concannon, PharmD discusses cytomegalovirus prophylaxis in solid organ transplantation. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities. Episodes originally aired from 2016 to 2021. Originally released: February 13, 2019 In the second half of our two-part series on complications of organ transplantation, Dr. Raj Dhar (Neurocritical Care, Washington University in St. Louis) discusses his experience managing the noninfectious complications of organ transplantation--from drug toxicities to multidisciplinary medical care. Produced by James E Siegler and Raj Dhar. Music by Steve Combs, Lee Rosevere, and Scott Holmes. Sound effects by Mike Koenig and Daniel Simion. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making. Be sure to follow us on Twitter (now X) @brainwavesaudio for the latest updates to the podcast. REFERENCES Dhar R, Young GB, Marotta P. Perioperative neurological complications after liver transplantation are best predicted by pre-transplant hepatic encephalopathy. Neurocrit Care 2008;8(2):253-8. PMID 17928960Dhar R. Neurologic complications of transplantation. Handb Clin Neurol 2017;141:545-572. PMID 28190435Mateen FJ, Dierkhising RA, Rabinstein AA, Van De Beek D, Wijdicks EF. Neurological complications following adult lung transplantation. Am J Transplant 2010;10(4):908-14. PMID 20121751Muñoz P, Valerio M, Palomo J, et al. Infectious and non-infectious neurologic complications in heart transplant recipients. Medicine (Baltimore) 2010;89(3):166-75. PMID 20453603Senzolo M, Ferronato C, Burra P. Neurologic complications after solid organ transplantation. Transpl Int 2009;22(3):269-78. PMID 19076332Wu Q, Marescaux C, Wolff V, et al. Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation. Eur Neurol 2010;64(3):169-77. PMID 20699617 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

It's Episode 13 of The Nephron Segment and it's time for NephMadness! Join us as we chat with transplant nephrologist Dr. Roslyn Mannon & transplant hepatologist Dr. Elizabeth Aby and discuss all things dual-organ transplantation: liver-kidney, pancreas-kidney, kidney after liver, kidney after pancreas, or even kidney alone?! Listen to the end to hear everyone's picks for NephMadness 2024.And to be clear, Dr. Mannon supported the Kansas City Chiefs before their Super Bowl 58 win.Submit your NephMadness brackets here (just like March Madness!) by 3/31. Maximize your changes by submitting 2 brackets per email address.Nephrons: Matthew Sparks, Samira FaroukGuests: Roslyn Mannon, Lizzie Aby

On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the March issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Marty Tam, MD, an advanced heart failure and transplant cardiologist at University of Michigan in Ann Arbor, hosts this episode.   First, Dr. Tam and Digital Media Editor David Schibilsky, MD interview their first guests, Fiorella Calabrese, MD and Francesca Lunardi, MD, ScD, PhD, of University of Padova, in Padova Italy. Dr. Lunardi was first author and Dr. Calabrese was senior author on the study “Assessing the role of phosphorylated S6 ribosomal protein in the pathological diagnosis of pulmonary antibody-mediated rejection.” In the conversation, Drs. Calabrese and Lunardi share the main challenges in the current diagnostic algorithm for AMR in lung transplantation, and why this protein expression may be a future mainstay in evaluating patients with this condition.   Next, Dr. Tam and Digital Media Editor Van-Khue Ton, MD, interview their next guest, Benjamin Mackie, MD, of Tampa General Hospital. Dr. Mackie was senior author on the study “Relationship between blood and tissue-based rejection-related transcripts in heart transplantation.” In the conversation, Dr. Mackie shares the current state of rejection assessment, including new, non-invasive modalities, and how the relation between these diagnostic methods may inform clinical practice.   Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Mark Skylar-Scott is one of the world's foremost experts on the 3D printing of human tissue, cell by cell. It's a field better known as bioprinting. But Skylar-Scott hopes to take things to a level most never imagined. He and his collaborators are working to bioprint an entire living, working human heart. We're printing biology, Skylar-Scott tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Episode Reference Links:Skylar-Scott LabConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionHost Russ Altman introduces the episode, guest Mark Skylar-Scott and his work bioprinting the heart.(00:02:15) What is Bioprinting & Tissue Engineering?Explanation of bioprinting and its distinction from traditional 3D printing. Overview of the technology and its applications in tissue engineering and how to get the cells for this purpose.(00:06:37) Engineering the Cells of the HeartThe 11 different cell types of the heart that are being created, and the steps involved in printing them, scaffolding them, and how they form tissue.(00:12:23) Building Hearts: Size and Growth ConsiderationsThe scale of bio-printed hearts, potential strategies for growth and integration, & technical challenges in controlling cell growth and development. (00:15:05) Scaling Up Cell ProductionThe importance of scaling up cell production for efficient experimentation. Exploration of the transition from laboratory research to clinical implementation. (00:18:40) Vascularization: The Key to Functional Bioprinted OrgansCritical importance of creating a comprehensive vascular network & the challenges of integrating capillaries and ensuring nutrient delivery to all cells. (00:23:00) Ethical Considerations in BioprintingExamination of the ethical issues surrounding the use of human cells in bioprinting, focusing on consent and the potential for inequality in access due to cost.(00:26:12) The Future of Bioprinting: Timeline and Field DynamicsProjections about the timeline for the clinical application of bio-printed organs and the state of collaborative competition within the fabrication field. (00:28:28) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the February issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Van-Khue Ton, MD, a transplant cardiologist at Massachusetts General Hospital, hosts this episode.   First, Dr. Ton and Digital Media Editor Erika Lease, MD interview their first guest, David Jenkins, FRCS(Cth), of the Royal Papworth Hospital in Cambridge, UK. Dr. Jenkins was senior author on the study “Perioperative extracorporeal membrane oxygenation support for pulmonary endarterectomy: A 17-year experience from the UK national cohort.” In the conversation, Dr. Jenkins shares the major determinants of mortality in this patient population, differences between survivors and non-survivors, and the CTEPH classification systems involved.   Next, Dr. Ton is joined by Digital Media Editor Marty Tam, MD, to interview their next guest, Kevin Chen, a 4th year general surgery resident at Cedars-Sinai Medical Center. Dr. Chen was a first author on the study “Heart transplantation in patients from socioeconomically distressed communities.” Drs. Ton and Tam lead a lively discussion about this important paper, including the methodology behind the indices used to categorize patients, and the million-dollar question: why did patients from distressed communities fare more poorly?   Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

A recent report suggested that Indian men outrank women as organ recipients. Meanwhile, women are far more likely to donate their organs to male counterparts within their families. Further, the proportion of organ donations from deceased persons is minuscule as opposed to living donors. In this episode, Saurabh Todi and Shrikrishna Upadhyaya discuss the reasons behind the gender disparities in organ transplants in India and certain solutions to solve the demand and supply mismatch in the organ transplantation market. Reading: 4 of 5 living organ donors in India are women, 4 of 5 recipients men: Study | Pune News Do check out Takshashila's public policy courses: https://school.takshashila.org.in/courses We are @‌IVMPodcasts on Facebook, Twitter, & Instagram. https://twitter.com/IVMPodcasts https://www.instagram.com/ivmpodcasts/?hl=en https://www.facebook.com/ivmpodcasts/ You can check out our website at https://shows.ivmpodcasts.com/featured Follow the show across platforms: Spotify, Google Podcasts, Apple Podcasts, JioSaavn, Gaana, Amazon Music Do share the word with your folks  See omnystudio.com/listener for privacy information.

A pioneer and an icon in diabetes research, Camillo Ricordi, M.D., is the Professor of Surgery, Director of Cell Transplant Center and Director Emeritus of the Diabetes Research Institute at the University of Miami Miller School of Medicine, Florida (UM-DRI). He joins Cell & Gene: The Podcast's Erin Harris to discuss the biggest and most troubling challenges facing the treatment of Type 1 Diabetes (T1D). They also discuss the future of cell and organ transplantation in treating T1D as well as the latest innovations in biopreservation. 

Heart failure impacts more than 8 million people in the United States today, but with the right treatments, the course of the disease can be corrected. Dr. Nir Uriel is determined to do just that. He's spent his career pushing forward advancements to better diagnose and treat advanced heart failure patients. These advancements include a new, magnetic levitated pump that can improve the outcomes of patients denied transplantation due to their age or severity of disease, as well as breakthrough testing that analyzes cell-free DNA to detect transplant rejection, changing the course of immunosuppressive therapy. Dr. Uriel is also pioneering the use of technology to remotely monitor heart failure patients, and diagnose heart failure before symptoms even occur. In this episode, Dr. Uriel details his multifaceted methods to treating heart failure, the value of a team approach, and the importance of empathetic, patient-centered care.

In this episode Alin and Colby  welcome on Dr. Rohan Goswami. Dr. Goswami is an advanced heart failure and transplant cardiologist at the Mayo Clinic in Jacksonville Florida. He specializes in the use of AI in the field of heart transplantation and the use of mechanical support systems as a bridge to recovery or a bridge to heart transplantation. This episodes discussions on both of those topics and much, much more! 

The JHLT Digital Media Editors explore two manuscripts from the July issue of The Journal of Heart and Lung Transplantation—one on heart transplantation and one on lung transplantation. Digital Media Editor Marty C. Tam, MD, Assistant Professor at the University of Michigan, hosts this episode.   First, hear from co-first author Kevin Chen, MD, on his team's study “Donation after circulatory death heart procurement strategy impacts utilization and outcomes of concurrently procured abdominal organs,” which comes from Cedars-Sinai. The study looks into the results of DCD organ donation depending on the technique used at procurement, mainly comparing ex-situ normothermic organ perfusion with thoracoabdominal normothermic regional perfusion (TA-NRP).   Digital Media Editors David Schibilsky, MD, and Van-Khue Ton, MD, have questions on the relationship between DCD liver and kidney procurement and heart procurement strategies, why TA-NRP livers and kidneys might differ, and the lower incidence of delayed graft function in DCD kidney transplants with TA-NRP. Dr. Chen also shares some thoughts about how this work might be incorporated into clinical practice.   Next, the editors welcome first author Jonathan P. Singer, MD, MS, from UCSF, to discuss the paper “Development of the Lung Transplant Frailty Scale (LT-FS).” Based on previous work, Dr. Singer and his colleagues set out to develop a novel frailty scale specifically for lung transplant candidates with improved performance characteristics over other frailty scales. The authors developed three lung transplant frailty measures and compared the construct and predictive validity to the existing short physical performance battery (SPPB) and the fried frailty phenotype (FFP). Their LT-FS models exhibited superior construct and predictive validity to these measures—and the addition of muscle mass and biomarkers further improved the model's performance.   Digital Media Editor Erika Lease, MD, digs in with Dr. Singer on the main findings of the study. What's unique about patients with advanced lung disease that makes them need a more specific frailty scale? How does the LT-FS outshine prior models? And what are the barriers to implementing a new model like this one in a transplant center?   Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation.  Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.    

In this episode we discuss the use of bugs (insects, arthropods, and the like) in medicine and medical research. Specifically, Mia serves us an overview of historical medical treatments using insect pulps and mashes, and Salem covers the modern use of bugs in medicine and research. As you may have heard, maggots are huge in wound treatment, but perhaps more surprisingly, helminths and spiders are also of interest to medical professionals/researchers. We also briefly mention leeches, though we don't spend too much time on them since we've already talked about their properties in the Organ Transplantation episode, so go listen to that! And remember: thank a bug today.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week the boys deep dive into the very VERY dark and twisted history of organ transplantation. In particular, Jer tells the boys about the role that Vladimir Demikhov played in it all. Demikhov was a Soviet scientist and organ transplant pioneer referred to as “the father of heart and lung transplantation.” But he isn't only famous for his work in discovering how we can transplant organs in humans. He's arguably more famous for his bat-sh*t crazy off-the-wall work in trying to create a two-headed dog. For a little palate cleanser - did you know that the water you're cleansing your palate with is just dino piss? Will AI replace the jobs of lifeguards? Finally, did you know that there are a number of animals that have “virgin births”? Crocs have recently been added to the list. Join the post-episode conversation over on Discord! https://discord.gg/expeUDN

This week the boys deep dive into the very VERY dark and twisted history of organ transplantation. In particular, Jer tells the boys about the role that Vladimir Demikhov played in it all. Demikhov was a Soviet scientist and organ transplant pioneer referred to as “the father of heart and lung transplantation.” But he isn't only famous for his work in discovering how we can transplant organs in humans. He's arguably more famous for his bat-sh*t crazy off-the-wall work in trying to create a two-headed dog. For a little palate cleanser - did you know that the water you're cleansing your palate with is just dino piss? Will AI replace the jobs of lifeguards? Finally, did you know that there are a number of animals that have “virgin births”? Crocs have recently been added to the list. Join the post-episode conversation over on Discord! https://discord.gg/expeUDN

In the United States today, there are over 110,000 people waiting for an organ transplant. And, Dr. Sandip Kapur says, 92% of those patients are waiting for a kidney. In this episode, Dr. Kapur describes a simple philosophy that helped guide Weill Cornell Medicine into one of the top kidney transplantation centers in the nation: offer the maximum amount of opportunities to transplantation that could exist. That means working with multidisciplinary teams to innovate every step of the kidney transplantation process– from making donor surgeries minimally invasive, to matching donors and recipients in new ways through the National Kidney Registry, and even pioneering research into immunotherapy, to improve success rates and patients' quality of life post-surgery.For more information visit nyp.org/Advances

Puneet Sood, MD, Medical Director, UPMC Kidney and Kidney Pancreas Transplant Program, discusses some of the misconceptions about living-donor organ transplantation and explains the process for both donors and recipients.

Puneet Sood, MD, Medical Director, UPMC Kidney and Kidney Pancreas Transplant Program, discusses some of the misconceptions about living-donor organ transplantation and explains the process for both donors and recipients.

In this episode, we review clinical pearls and common pitfalls of immunosuppression regimens for organ transplantation with a particular focus on tacrolimus and mycophenolate. Key Concepts Most recipients of an organ transplantation will be on a two or three drug regimen. The most common regimen is tacrolimus and mycophenolate with/without a corticosteroid. Tacrolimus is hepatically eliminated and susceptible to CYP3A4 and PGP drug interactions. Particularly at higher drug concentrations, it is associated with nephrotoxicity and neurotoxicity (among several other adverse effects). Mycophenolate is unstable in the acidic environment of the stomach. The two formulations on the market are CellCept (which uses a prodrug, mycophenolate mofetil, that is converted in the liver to an active compound) and Myfortic (an enteric-coated formulation of mycophenolic acid, which releases after exiting the stomach). The intensity of an immunosuppression regimen is determined by numerous factors, including the type of organ, how long ago the organ was transplanted, if acute rejection has occurred in the past, patient-specific risk factors, and more. Additional Resources Register to be a donor at Donate Life America (https://donatelife.net) or at the HRSA OrganDonor.gov site (https://www.organdonor.gov) Learn more about stem cell donation and transplant at https://bethematch.org

Today's guest is the Israeli sociologist, Hagai Boas, a four-time organ transplant recipient and the author of The Political Economy of Organ Transplantation, published by Routledge. Hagai is the second transplant recipient on the podcast (Sally Satel, an earlier guest, has received two kidney transplants), but I've never met anyone before who has been transplanted *four* times, or who has purchased an organ on the black market, as Hagai did with his third transplant. Boas is the director of the Science, Technology, and Society unit at Van Leer Jerusalem Institute. He is also a senior lecturer in the Department of Politics and Government at Ben-Gurion University. 

Host Catherine Price and Dr. Emile Bacha, Chief of the Division of Cardiac, Thoracic, and Vascular Surgery at NewYork-Presbyterian/Columbia discuss the history of heart surgery, ventricular assist devices, and a new frontier in cardiac surgery: The Total Artificial Heart. Dr Bacha tells the groundbreaking story of successfully fitting a pediatric patient with a Total Artificial Heart. He explains the nuances of the procedure, and how a backpack-powered heart gave his pediatric patient another chance. The views shared on this podcast solely reflect the expertise and experience of our guests. For more information visit nyp.org/Advances

Join science journalist Catherine Price as she sits down with top physicians from NewYork-Presbyterian hospital to discuss advances in their latest research, pioneering new treatments, and compassionate patient practice. From the most complex cases in pediatric surgery, to the way AI will improve disease detection and diagnostics – the work of these physicians is united by a collective mission to transform what it means to deliver patient-centered care. This is a show for healthcare professionals looking for the inside story – and real human details – behind some of medicine's greatest leaps forward. For more information visit nyp.org/Advances  

In this latest episode of ASTCT Talks, Dr. Firas El Chaer talks with Dr. Alpana Waghmare and Dr. Michael Ison to discuss the winter “Tridemic,” which includes COVID, flu and respiratory syncytial virus (RSV). They discuss the diagnostic and treatment approaches for the Tridemic in recipients of hematopoietic cell transplantation and cellular therapy, examine the precautions and best practices for recipients of hematopoietic cell transplantation and more. This podcast was recorded on December 21, 2022. About Dr. Firas El Chaer Firas El Chaer, MD, (@FirasElChaer) is an assistant professor of medicine who specializes in hematology and oncology. He completed a fellowship in infectious diseases for immunocompromised cancer patients at the combined program of Baylor College of Medicine and MD Anderson Cancer Center in Houston, Texas. He then pursued a fellowship in hematology and oncology with a focus on blood disorders. Also, he completed a built-in fellowship in stem cell transplantation at the University Of Maryland School Of Medicine. His clinical areas of interest are acute leukemia, chronic leukemia, myelodysplastic syndrome, myeloproliferative disorders, aplastic anemia, and clonal hematopoiesis and blood disorders. His research focuses on improving outcomes for acute leukemia in adults by focusing on targeted therapies and overcoming resistance mechanisms. About Dr. Alpana Waghmare Alpana Waghmare, MD, (@alpanaw) is a pediatrician who specializes in the treatment and prevention of infectious diseases with a focus on respiratory infections and their impact on vulnerable populations. Her work on viral infections in immunocompromised patients includes the often-overlooked pathogen, human rhinovirus, or HRV, which is a cause of head colds. She is working on numerous COVID-19 projects, such as studying infections in cancer patients who have received transplants or CAR T-cell therapy, and studying the host transcriptome in both healthy and immunocompromised patients in acute SARS-CoV-2 infection. About Dr. Michael Ison Michael Ison MD, MS, (@MichaelGIsonMD) completed his medical school training at University of South Florida College of Medicine and the obtained training in Internal Medicine at Oregon Health Sciences University in Portland, Oregon followed by Infectious Diseases at the University of Virginia and Transplant Infectious Diseases Training at Massachusetts General Hospital/Harvard Medical School. After spending 17 years as a Professor in the Divisions of Infectious Diseases and Organ Transplantation at Northwestern University Feinberg School of Medicine, he moved to become the Respiratory Disease Branch Chief within the Division of Microbiology and Infectious Diseases at NIAID/NIH. He also currently serves as the Editor-in-Chief of Transplant Infectious Disease.

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/public-policy

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/economics

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/law

This is the story of organ transplantation, told from the organ's point of view. Organs for transplantations come from two sources: living or post-mortem organ donations. These sources set different routes of movement from one body to another. Postmortem organ donations are mainly sourced and allocated by state agencies, while living organ donations are the result of informal relations between donor and recipient. Each route traverses different social institutions, determines discrete interaction between donor and recipient, and is charged with moral meanings that can be competing and contrasting. The political economy of organs for transplants is the gamut of these routes and their interconnections, and this book explains what such a political economy looks like: its features and contours, its negotiation of the roles of the state, market and the family in procuring organs for transplantations, and its ultimate moral justifications. Drawing on Boas' personal experiences of waiting, searching and obtaining organs, each autobiographical section of the book sheds light on a different aspect of the political economy of organs – post-mortem donations, parental donation, and organ market – and illustrates the experience of living with the fear of rejection and the intimidation of chronic shortage. Boas combines a rigorous academic analysis of the political economy of organ supply for transplantation with autobiographical narratives that illuminate the complex experience of being an organ recipient. The author, Hagai Boas invites your comments and questions. Contact him at Hagaib@vanleer.org.il Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network's Van Leer Jerusalem Series on Ideas. Write her at reneeg@vanleer.org.il. She's on Twitter @embracingwisdom. She blogs here Learn more about your ad choices. Visit megaphone.fm/adchoices

Timestamps:0:00 Intro01:54 How did you get started in the field of histocompatibility?03:44 Was that a mentor that helped you find this new role and pathway, or was there a particular patient that you took care of that opened your eyes to these other possibilities in lab medicine?05:28 What are a few things that you think healthcare professionals in general should understand about organ transplantation?07:51 Maybe for you, as someone who was practicing first in orthopedic surgery, and then making this transition to systems thinking, what has that been like and how do you navigate that now?09:23 How does the laboratory and histocompatibility support organ transplantation? What kind of work happens behind the scene that enables this transplant to be as successful as possible?11:53 Is the laboratory involved with the care of the transplant patient beyond the acute transplant? What does that look like?13:09 What do you predict is on the horizon for histocompatibility?14:50 How could somebody support organ transplantation?16:47 Outro

In this episode, Alex chats with Dr. Robert Montgomery, one of the world's foremost organ transplantation and research experts. Dr. Montgomery is the Chairman and Professor of Surgery at NYU Langone Health and is the Director of the NYU Langone Transplant Institute, one of the US' top transplant centers. Dr. Montgomery has been at the forefront of organ transplantation for decades as both a surgeon and a patient. He was the first surgeon to receive an implantable defibrillator after a genetic heart condition caused multiple cardiac arrests. Later, he received a heart transplant as a patient in the first clinical trials with hepatitis C-positive hearts. He was part of the teams that developed the laparoscopic procedure for live kidney donation, conceived the idea of domino-paired donations, created the Hopkins protocol for desensitization, and, more recently, completed the first successful investigational kidney and heart xenotransplantations. We discuss:The life & death & life & death & life of Robert Montgomery: the story of his heartThe state of the organ transplantation field: problems with quantity, quality, and consistency How does the US organ transplant waitlist work?Different organ sources: live donors, deceased donors, altruistic donors, domino transplants, hepatitis-C positive donorsThe opioid epidemic in the context of organ transplantation: a harrowing source of organsCutting-edge research: how xenotransplantations and bioartificial organs can solve the organ transplantation crisisAdvanced surgical methods: robotics and AI in organ transplantsHow to style your mustache with the world's foremost expert in organ transplantation

Molly A. McCord, PharmD, describes pediatric-specific differences in pharmacokinetics as it applies to commonly used immunosuppressants, discusses concerns related to medication formulations, monitoring, and adherence in the pediatric population, reviews pediatric solid organ transplantation pharmacotherapeutic controversies in immunosuppression and infection prevention. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter! You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.   

We've talked about blood transfusions, now it's time for its sister field: organ transplantations! Just like blood transfusions relied on ABO compatibility to work, organ transplantation scientists ran into the issue of immune system compatibility- something that is still giving us trouble. We talk about how the field evolved through time, and how the discovery of immunosuppressants contributed to safer transplants- kinda. We also discuss sketchy practices and practitioners, and the future of transplants in the form of immune cells, biopolymers or perhaps xenotransplants.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Stacy A. Bernard, PharmD, BCPS, BCTXP, reviews anti-hypertensive agents and their use in the longitudinal care of a solid organ transplant patient, relates drug-drug interactions between statins and immunosuppressive therapies to dyslipidemia treatment decisions in a solid organ transplant patient, discusses short- and long-term considerations when selecting an anticoagulation regimen for a solid organ transplant patient. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter! You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.   

There's a lot behind organ transplantation. Which organs can we transplant? When does someone need a transplant? How do we choose who gets one? And what are the ethical dilemmas surrounding transplantation? In this episode, we answer all these questions and more, including what patients can do to advocate for themselves if they do find themselves needing a transplant. We also explore UChicago Medicine's unique role in the history of liver transplantation and debunk common misconceptions about the field, including the myth that doctors will change the quality of care if someone is listed as a organ donor. They don't!Dr. Michael Millis is a Professor of Surgery and the Vice Chair of Global Surgery at UChicago Medicine. He is an expert in adult and pediatric transplant surgery. Dr. Millis is also a pioneer of new techniques for liver operation. His innovations have helped the University of Chicago perform more liver transplants than any other program in the region over the past 15 years. Dr. John Fung is a Professor of Surgery and the Chief of the Section of Transplant Surgery at UChicago Medicine. He is a renowned leader in the field of organ transplantation, including liver, kidney, pancreas, and intestinal transplantation. Dr. Fung has spearheaded the use of new minimally invasive surgical transplant techniques. Dr. Fung was one of the physicians leaders of the transplant care team that made history in December 2018, after performing two triple-organ transplants within 27 hours.Dr. Milda Saunders is an Associate Professor of Medicine at UChicago Medicine and the Interim Associate Dean for Health Equity, Diversity, and Inclusion at the Pritzker School of Medicine. Dr. Saunders' broad research interests include health disparities and quality of care, particularly related to chronic kidney disease. Her work has examined how a person's residence and site of care are associated with health outcomes. Dr. Kumaran Shanmugarajah is a fourth year surgery resident at UChicago Medicine and the Scientific Director of the Organ Perfusion Lab. He has worked internationally exploring the clinical application of basic science innovation. His interests include transplant immunology, organ engineering, and healthcare delivery models.“Deep Cuts: Exploring Equity in Surgery” comes to you from the Department of Surgery at UChicago Medicine. Our host is Dr. Jen Vigneswaran. Our senior producer is Tony Liu. Our engineer is Paul Braun. Our podcast cover art comes to you from Pombie Silverman, episode art from Sam Higgins, and music from Sen Morimoto off of Sooper Records. A special thanks this week to Reem Hamoda.