The Clinical Research Podcast

An interview with Dr Chloe Anthias, medical director of the new Cell Collection Centre has just opened by Anthony Nolan charity as part of our NIHR Nottingham Clinical Research Facility. Links a little while ago I talked to Prof Mark Bishton, who's an oncologist at the hospital about stem cell research. Listen here NIHR Nottingham Clinical Research Facility To find out more about the Anthony Nolan Cell Collection Centre, to donate to Anthony Nolan or to find out how to join the stem cell register, visit: www.anthonynolan.org This Podcast is brought to you by the NIHR Nottingham Clinical Research Facility. Follow us on @NottmCRF, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

This bulletin intro was brought you by Harriet Anderson from Research and Innovation Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. Tags: #SAPhEStudy, #Nanopore #SequencerDevice, #Tech, #RoundTableTalks, #PRES #BrainTumor Links Nanopore - https://nottinghamcrf.nihr.ac.uk/about/news/nottingham-leads-the-way-dna-sequencing-technology-could-transform-brain-tumour-diagnosis Patient transfers - nuhnt.GetInvolved@nhs.net Loughborough University round-table talks about dementia care and research - Neil.chadborn@nottingham.ac.uk. R&I Clinical support department showcase - i.antonopoulou@nhs.net Participant research experience survey - https://sites.google.com/nihr.ac.uk/crneastmidspres/survey SAPhE study - SAPhEstudy@nuh.nhs.uk This Podcast is brought to you by the ⁠Research & Innovation team at Nottingham University Hospitals NHS Trust⁠. Follow us on ⁠@ResearchNUH⁠ and ⁠@NottmBRC⁠, or email ⁠R&Icomms@nuh.nhs.uk⁠. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

Asthma is one of the most common conditions - there are 8 million of us in the UK who suffer from it.  t can range from the needing a quick puff on your inhaler if you exercise and there's a lot of pollen about it, to serious, fatal attacks, there's still a lot we don't know. That's what this interview with our respiratory physician Matthew Martin is all about. One of the things we're not sure about is to do with how people with inhalers use them - short version, we might doing it all wrong, then again we might not, this is research after all - and that's what  the second bit of the interview you're about to hear covers. More on the APEX trial: https://nottinghambrc.nihr.ac.uk/research/respiratory/airway-disease-theme

This bulletin intro was brought to you by Ian Kingsbury from East Genomics Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. #BioResource, #GLADstudy, #NIHR, #Chest drains, #PneumocystisPneumonia, #NottinghamUniversityHospitals Links East Genomics – https://www.eastgenomics.nhs.uk/ Join the world's largest study of anxiety & depression - https://gladstudy.org.uk/ PCP – If you are interested in contributing to the development of this research proposal, please contact Vikki Flemming, Consultant Clinical Scientist, Clinical Microbiology, vicki.fleming@nuh.nhs.uk  Chest drain - So If you, or someone you care for, has had a chest drain fitted as part of their treatment, please email: GetInvolved@nuh.nhs.uk BioResource – bioresource.nihr.ac.uk or Joanne.Llewellyn@nuh.nhs.uk This Podcast is brought to you by the ⁠Research & Innovation team at Nottingham University Hospitals NHS Trust⁠. Follow us on ⁠@ResearchNUH⁠ and ⁠@NottmBRC⁠, or email ⁠R&Icomms@nuh.nhs.uk⁠. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

One of the fundamentals of clinical research is the ‘blind' bit of the double-blind placebo controlled trial. If neither the researcher nor the participant know whether they're getting placebo or the drug, it removes the chances that they're unconsciously  responding in the way they think they should.  The placebo effect can account for up to 30% of a difference, so it has to be dealt with. But if you're trialling a therapy where the patient will know what's going on - like exercise for rehab, for example - it can't be blind. So how do you get round that? We spoke to clinical research  physiotherapist Paul Matthews about the challenges he faced when he was studying exercise as part of rehab for broken ankles. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

The intro this week was from Harriet Anderson, who works in the Research and Innovation team at Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at R&Icomms@nuh.nhs.uk. Links Mental health citizen science - www.gladstudy.co.uk Participant in Research Experience Survey - The results for NUH: https://www.nuh.nhs.uk/ri-feedback, and for people in the East Midlands: https://sites.google.com/nihr.ac.uk/crneastmidspres/survey NHS East Genomics - https://www.eastgenomics.nhs.uk/for-healthcare-professionals/genomic-tests/ Liver walks: email Abhishek Sheth at nuhtnt.nottinghamhepatology@nhs.net LifeArc Centre for Rare Respiratory Diseases Willow Tranter appeal - https://www.justgiving.com/page/willowsjourneywithall and Cure Leukaemia https://www.cureleukaemia.co.uk/ Babi study - https://www.babinetwork.co.uk/ This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

You'd think that clinical researchers would welcome surprises - but they don't. Even if the results are new and groundbreaking, they want their trials and studies to run in a predictable, controlled way,. And that ability to deliver a total lack of surprise is one of the reasons that cancer research at Nottingham University Hospitals NHS Trust has made it into the top flight in the UK working with major pharmaceutical companies.  As well as clinical and scientific excellence, it's about building up relationships with our partners so that we know we can deliver on recruiting patients, managing the pharmacy needs, and study set up.  The focus is particularly on chemo-free approach to lymphoma treatment, immunotherapy such as CAR T therapy, bispecific antibodies and using data analysis to target treatments. I talked to Professor Mark Bishton, who's a consultant haemotologist and the divisional co-lead for research and innovation into cancer and associated. As well as his own research, he's responsible for delivering the trust's studies in the specialty. More information at https://www.nuh.nhs.uk/research-in-cancer This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Staff at the NIHR Nottingham Clinical Research Facility talk about the UCAB trial. The facility worked with Swedish pharmaceutical Umecrime Cognition to study using a new molecule as a treatment for Primary Biliary Cholangitis (PBC) for patients with severe symptoms of fatigue and cognitive impairment. Quick takeaways -      • one of only two UK locations for first stage drug trial     • kept to tight, complex timelines     • exceeded recruitment targets by building on existing relationships     • patients praised care and treatment The NIHR Nottingham Clinical Research Facility (CRF)  was one of just two centres worldwide – and the only UK facility – to conduct the first part of a clinical study. We were picked because of our expertise in liver disease. We hosted five patients on a purpose-built inpatient ward within the CRF, to confirm the correct dose of the molecule. During their seven-day stay, our team of research nurses and physicians assessed and cared for the patients around the clock. Nottingham CRF has 18 adult and five paediatric inpatient beds dedicated for research, alongside our dedicated outpatient and specialist clinics. In total, there is over 3,400m² of clinical space at our CRF. The PBC study was a randomised, double-blinded and placebo controlled two-part study to evaluate the pharmacokinetics, safety and tolerability, and preliminary efficacy of two dose levels of the new drug. There's more about it at https://nottinghamcrf.nihr.ac.uk/facilities/case-studies Follow us on Twitter: @NottmBRC Follow us on Instagram: @NottmHealthScience Follow us on Facebook: https://www.facebook.com/ResearchNottingham Watch a video explainer about clinical trials: https://youtu.be/SWS4FCSMWAQ  Read more at https://www.nottinghamresearch.org/get-involved and https://www.nuh.nhs.uk/take-part-in-a-trial and https://www.nuh.nhs.uk/researchvolunteers Email us at  getinvolved@nuh.nhs.uk

Contacts for his episode: COACH trial for hearing aids vs cochlear implants - More information from coachtrial.ac.uk or email coach@nottingham.ac.uk Ultrasound probe for people with trauma injuries - contact Georgia Melia at georgia.melia@nuh.nhs.uk The studies in Norfolk and Leicester into communities and genomics - www.eastgenomics.nhs.uk or email the East Genomic Medicine Service Alliance (GMSA) at egmsa@nnuh.nhs.uk The Healthcare Scientists Research Showcase tickets are at  https://www.eventbrite.co.uk/e/healthcare-scientists-research-showcase-tickets-835899837917

Bulletin 9 - developing treatments for cystic fibrosis, depression, alcoholic liver disease and eczema In this episode: We pick up on presentations from the NIHR Nottingham BRC conference, from: Dr Helen Barr, on matching medicines to gene for CF patients Prof Richard Morriss on treating depression and anxiety with transcranial magnetic stimulation - https://www.mindtech.org.uk/news-events/latest-news/brightmind-trial-improves-the-lasting-effects-of-treatment-for-severe-depression A Q and A on alcoholic liver disease - https://youtu.be/orJBGWAo8fM Finding out how often should you shower if you eczema - rapideczematrials.org/eczema-bathing-study Our YouTube channel: @NottinghamClinicalResearch This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

In this bulletin: Testing the Respirasense breathing monitor from PMD Solutions - https://www.pmd-solutions.com - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3944-respirasense-trial Bone graft augmentation and gene therapy research with Theragenix - https://theragenix.health/ https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3942-nearly-1m-for-pioneering-gene-therapy-formulation-for-bone-graft-augmentation Rib fracture pain relief - https://orif.octru.ox.ac.uk/ https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3949-can-innovative-surgery-cut-mortality-after-major-trauma-injuries Medicine showcases Clinical Academie Research Partnership awards - https://www.nihr.ac.uk/documents/clinical-academic-research-partnership-carp/30439 Robot urology surgery to lessen erectile dysfunction - https://www.theurologyfoundation.org/get-involved/urology-awareness-month

In this bulletin: Secure Data Environments - ⁠https://transform.england.nhs.uk/key-tools-and-info/data-saves-lives/secure-data-environments/⁠ Prof Guru Aithal appointed new medical lead for the Eastern Genomic Medicine Service Alliance - ⁠https://www.eastgenomics.nhs.uk Showcase of gastro intestinal research at Nottingham⁠ Meet the respiratory research team - with pizzas Networking for early career imaging researchers If you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get  your podcasts.  The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk, or visit nuh.nhs.uk/research for more information. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially.

Links to show items Equity in Doctoral Education through Partnership and Innovation programme - https://www.ntu.ac.uk/c/equity-in-doctoral-education-through-partnership-and-innovation MRI PhDs - https://www.nottingham.ac.uk/research/beacons-of-excellence/precision-imaging/current-opportunities/studentships/nihr-nottingham-brc/index.aspx AERIFY study - https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/aerify-3/ AMAS report - https://acmedsci.ac.uk/policy/policy-projects/future-proofing-uk-health-research AMAS video - https://youtu.be/tWduBG3XSBE QGenome - https://www.eastgenomics.nhs.uk/about-us/news-and-events/launch-of-qgenome-across-the-east-gmsa/ Roman Foundation - https://theromefoundation.org/rome-foundation-fellows/rome-foundation-fellows-2023/ CRF conference registration - https://meetinnottingham.bzon.uk/ukcrf23-registration/ Research Excellence Awards - https://www.nuh.nhs.uk/research-excellence-awards-2023 This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Spend an evening with blood, urine, saliva and Nottingham researchers, looking to the future of research at NUH, helping children and young people with mental crises, and how to show a researcher you love them. Links: BioResource event booking - https://www.eventbrite.com/e/574447577167 NUH medical director Keith Girling on why the Nottingham BioResource is good for patients – https://youtu.be/AC49MnM_CtY Previous podcast with Natasha Hill, Nottingham bioresource manager - https://youtu.be/bQJ0S4l7uF8 SaPHE study explained - https://youtu.be/ldtPG21slEo Book tickets to the SaPHE study even - https://www.eventbrite.co.uk/e/the-saphe-study-disseminationcelebration-event-tickets-549208496397 SaPHE study website - sites.google.com/nihr.ac.uk/saphepathway/home NIHR Nottingham Clinical Research Facility – www.nottinghamcrf.nihr.ac.uk NUH medical director Keith Girling on talks about the  CRF video - https://youtu.be/DWre8K7z4NQ UK CRF conference Registration - https://meetinnottingham.bzon.uk/ukcrf23-registration/ Staff awards - https://www.nuh.nhs.uk/research-excellence-awards-2023 Download a transcript of this episode. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

In this clinical research bulletin from Nottingham: Notts County legend Les Bradd has been helping our researchers investigating football-related injuries. https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3927-notts-county-fc-legend-les-is-helping-researchers-investigating-playing-injuries We hit national and international headlines this week for study which identified 500 genes linked to lung health https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3932-nottingham-researchers-lead-gene-study-to-enable-personalised-lung-health-care a review of Covid treatments for vulnerable people in Nottingham showed that being white, female and better-off, meant you were more likely to accept covid-19 treatment https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3930-white-female-better-off-vulnerable-patients-more-likely-to-accept-covid-19-treatment-nottingham-study-shows If you fancy spending an evening discussing the possible uses of blood, urine, saliva and body tissue, together with their related health data, then we have an online event you'll love - https://www.eventbrite.com/e/574447577167 If you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get  your podcasts.  The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC or email R&Icomms@nuh.nhs.uk, or visit nuh.nhs.uk/research for more information. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially.

In this episode - clinical research news of ASSIST MS study, World Hearing Day, NIHR researcher appointments, Liver Partnership launch, and the Tummy Tracker app for cystic fibrosis patients. Links ASSIST-MS - https://www.nihr.ac.uk/news/ground-breaking-ai-research-aims-to-improve-tests-and-treatments-for-thousands-of-patients/32852 World Hearing Day - https://worldhearingday.org/ Nottingham partnership - 3925-people-living-with-dementia-and-hearing-conditions-invited-to-shape-future-research Prof Morriss reconfirmed - https://arc-em.nihr.ac.uk/news-events/news/arc-east-midlands-theme-lead-reappointed-nihr-senior-investigator NIHR Nottingham BRC Mental Health and Technology researchers -https://nottinghambrc.nihr.ac.uk/research/mental-health-technology/mental-health-technology-team NIHR Nottingham BRC leadership team - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/leadership-team KLIFAD open access registration - https://bmjopen.bmj.com/content/bmjopen/11/11/e054954.full.pdf Dr Subhani talks about the Liver Partnership - https://youtu.be/7BZEB6VbeHQ NIHR Nottingham BRC Gastrointestinal & Liver team https://nottinghambrc.nihr.ac.uk/research/gastrointestinal-liver/gastrointestinal-liver-team CF Tummytracker app - https://cftummytracker.org This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUHand @NottmBRC, or email R&Icomms@nuh.nhs.uk, or visit nuh.nhs.uk/researchfor more information.

Weekly updates from research and innovation team at Nottingham University Hospitals NHS Trust and NIHR Nottingham Biomedical Research Centre Links Methotrexate study - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3925-methotrexate-study Tinnitus research - https://www.mdpi.com/2076-3425/12/4/484 PrAISED study - Video - https://youtu.be/VB6GET95Sgg - https://www.nottingham.ac.uk/research/groups/healthofolderpeople/projects/praised/ University of Nottingham respiratory research professorship application - https://jobs.nottingham.ac.uk/vacancy.aspx?ref=MED630022 CARP research grants - https://www.nihr.ac.uk/documents/clinical-academic-research-partnerships-carp/30439 BRAID breast cancer study - https://www.nottingham.ac.uk/research/groups/nottinghambreastcancerresearchcentre/index.aspx More information about research and innovation in general at Nottingham on the Nottingham University Hospital NHS Trust website which is www.nuh.nhs.uk/research, and about the NIHR Nottingham Biomedical Research Centre on our website, which is at nottinghambrc.ac.uk - and ourr email and social media links are there too. If you want to stay up to day with the clinical research podcast, you can find us on iTunes, Spotify, Google and where-ever you normally get your podcasts. The more shows are rated and reviewed, the easier it is for search engines to find us, so if you can subscribe and rate and review us, you'll be doing it for science.

We've launched a new podcast, it's a short update on research in Nottingham, and it's for both researchers and anyone interested in clinical research and it's out every fortnight. The first episode covers the Nottingham methotrexate study which has piqued worldwide interest and sparked tens of thousands of tweets, as well as research into dementia, tinnitus and breast cancer. We've also got details of grants, job vacancies and other support for researchers. If you're already subscribed to the Nottingham Clinical Research podcast, it'll show up in your feed without you doing anything at all. If you're not, search for Nottingham Clinical Research where-ever you normally get your podcast.

As the NIHR Nottingham Biomedical Research Centre embarks on its second tranche of funding, we're developing our existing partnerships with other clinical research organisations in the East Midlands, especially Nottingham Trent University. One of our closest links there is Professor John Hunt, who's Head of NTU's medical technologies and advanced materials research theme. He's also just taken on a role as deputy director of the NIHR Nottingham Clinical Research Facility, based at Nottingham University Hospitals NHS Trust. I talked to him about his own research in clinical sciences, and particularly biomaterials, as well as his new role at the clinical research facility Links NIHR Nottingham Biomedical Research Centre NIHR Nottingham Clinical Research Facility NTU's Medical Technologies Innovation Facility This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Chronic lung diseases are the third biggest cause of death in the world, and in Nottinghamshire, about 1 in 8 people have been diagnosed with asthma or COPD - so finding new treatments is high on the list for clinical researchers. And our particular expertise here is understanding how the disease works at a cellular level and it's why we're part of new £8.8million study funded by the Wellcome Trust. But environmental factors - like smoking, or working down a mine - are only part of the story. Genetic make up means some people are more at risk than others, and this study is about understanding how we can detect who's more likely to develop lung disease. It's being led here by Nottingham University Hospitals NHS Trust respiratory consultant Professor Ian Hall, who's also the director of the NIHR Nottingham Biomedical Research Centre. Read more about the announcement here. This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

October is a vital and important month for many ethnic minorities especially the Black community. In the UK Black History Month is celebrated every year with a different theme. This year's theme is ‘Action not words'. In recent years we have seen the rise of Black communities and individuals sharing their experiences about the inequalities and injustices they go through. In this episode we speak to Tony Ndung'u, an emergency department nurse with a passion for research. We discussed the meaning of this year's BHM theme, also his journey into research and Pre-doctoral Clinical and Practitioner Academic Fellowship Scheme also known as the PCAF, looking at where ethnic minorities get their health information particularly during the pandemic. The Health Education England (HEE)/NIHR scheme offers salaried time to develop a doctoral fellowship application and to undertake funded academic training. It's open to early career researchers from the health and care professions (excluding doctors and dentists) who are committed to a clinical academic or practitioner academic career.

Leaps forward in the understanding of the Human Genome in recent years stand to offer huge benefits to patients - including the possibility of personalised care. As a large acute hospital, Nottingham University Hospitals NHS Trust is one of the organisations at the forefront of this exciting health revolution, which also brings some challenges. But what does Genomics mean in reality to healthcare professionals working at NUH? And how can they access genetic medicine services - including testing for patients, in their day-to-day practice? Dr Matt Hall, a consultant nephrologist based at Nottingham University Hospitals NHS Trust, is medical lead for the Genomics Medicines Service Alliance (GMSA), which is trying to embed genetic medicine into everyday practice. Episode links: The National Genomic Test Directories - www.england.nhs.uk/publication/national-genomic-test-directories/ East Genomics – eastgenomics.nhs.uk. This includes information on how to request a test for your patients If you are a clinician: https://www.eastgenomics.nhs.uk/for-healthcare-professionals/genomic-tests/referral-forms-index/ Genomics Education resources – genomicseducation.hee.nhs.uk This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Genomics is the future of healthcare which we're told will revolutionise how patients are treated – but what is it, exactly? And how can healthcare professionals use it day to day? Dr Matt Hall, a Consultant Nephrologist at Nottingham University Hospitals NHS Trust, is the medical lead for the Genomics Medicines Service Alliance (GMSA), which means he's leading how genetic medicine is becoming embedded in everyday practice, and he's our next interviewee. So now's your chance to find out in the next episode the Clinical Research podcast.

Nottingham's long been a leader in researching and treating blood cancer - we pioneered blood stem cell transplantation and we're still one of the biggest centres in the UK. We bring together oncology, clinical haemotology, neuro imaging and surgery and over the last five years we've increased our experimental cancer research trials by 30 percent. So it's naturally one of the priorities of our new Clinical Research Facility, which recently had its £2.6 million pound funding confirmed by the National Institute for Health and Social Care Research. The Nottingham facility's team delivers early phase experimental trials not just in cancer, but across the board, including areas such as gastro intestinal disorders, inflammatory conditions, musculoskeletal conditions and respiratory diseases. It's closely integrated with the hospital and is expanding its inpatient, day beds and out patient facilities, including for children as well as adults. Its new deputy director is Professor Chris Fox, a consultant haematologist at Nottingham University Hospitals NHS Trust, who has a track record of research into lymphoma and stem cell transplantation, among other things. I spoke to him as he was taking up his new post. Links NIHR Nottingham Clinical Research Facility Follow Prof Fox on Twitter Cancer research at Nottingham University Hospitals NHS Trust This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Newly appointed NIHR Nottingham Clinical Research Facility deputy director Prof Chris Fox talks about cancer research.

However good research is, if it stays in the lab or on a hard drive somewhere, isn't going to help anyone and of course the reality is that researchers do literally get points for how many people see their publications. But how do you do that? How do break out of the world of peer reviewed journals and This episode is an interview with Rory Cellan Jones who was the BBC's tech editor so he's been explaining complicated stories to mainstream audiences - by which I mean non-technical audience =s - for forty years. Now he's freelance, publishing a weekly newsletter and tweeting about tech, and particularly health tech. He's also been diagnosed with Parkinson's so unsurprisingly he has a particular interest in its treatment. I met him recently at a conference organised by Health Data Research UK and sat down with him to pick his brains about the care and feeding of journalists - how researchers can get journalists' attention, how to explain complicated, nuanced ideas to journalists, and whether being a patient has given him a new perspective. Rory's Twitter is @ruskin147. He's the author of a book about social media use, 'Always On' and his newsletter is at https://rorycellanjones.substack.com This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

However good your research is, if it stays in the lab or on a hard drive somewhere, isn't going to help anyone, or let alone improve your REF number. But how do you cut through and explain your research to a wider audience? In the next episode of the Nottingham Clinical Research podcast, I talked to former BBC tech editor Rory Cellan Jones (@ruskin147)about how to explain science to non-scientists. You can hear our conversation on the Nottingham clinical research podcast by searching for - astonishingly - Nottingham Clinical Research podcast where-ever you usually get your podcasts, and explore the dozens of episodes also about - astonishingly - clinical research Nottingham. This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

One in eight women in the UK will be diagnosed with breast cancer, and like most cancers, the sooner it can be detected, the better the patient's prospects. That's why there's a national screening programme for women over fifty. which has been successful at cutting the mortality rate. But it's a one size fits all solution at a time where medicine is getting more personalised. Some breast tissue is denser than others, and the denser it is, the more likely it is to develop a cancer, and the more aggressive that cancer is likely to be. So anything that can help differentiate fom person to person what's going on, early on, will improve how effectively we can treat cancer. Being able to use dye to help imaging is one of those ways, and Nottingham University Hospitals NHS Trust was one of the first hospitals to be able to to carry out contrast mammograms using dye. That expertise has meant we're part of the BRAID trial the acronym in this case stands for Breast Screening – Risk Adaptive Imaging for Density and means we can offer it at early stage in the process. Dr Elisabetta Giannotti, a consultant breast radiologist, is leading the trial at Nottingham. More information on the the BRAID study website: https://radiology.medschl.cam.ac.uk/research/research-themes/breast-imaging/braid-trial/ This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

If your child was seriously ill enough that they had to take their nutrients through a tube into their stomach, you might assume as a parent, you'd follow everything medics told you to the letter. But a few years ago, doctors and nurses began to realise that rather than the prescribed commercial 'feed', a lot of those parents were giving their child real food - blended up. Researchers started to ask what the effect of this would be.  But for Professor Jane Coad, who's now head of Nottingham's Centre for Children and Young People's Health Research, there was a deeper question to ask. You can Prof Coad on Twitter at @CoadProfessor. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

When a child or young person comes to hospital in an emergency and mental health issues are clearly involved, how do we know how we can help them best? Health professionals can be unsure what to look for, what to do about they see, and how to judge how much they're helping the situation. Dr Joseph Manning MBE, a clinical academic nurse at Nottingham University Hospitals NHS Trust and NIHR lecturer at the University of Nottingham, is leading the SAPHE study which is researching how to make treatment of children and young people with mental health crises more effective and consistent. It's doing that by working **with** those children and young people. Joseph mentioned Prof Jane Coad, another of our researchers at Nottingham, and there's an interview with her coming up in and episode soon. Links SAPHE study website You can follow both @josephcmanning and Prof Jane Coad - @coadprofessor - on Twitter This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

When a child or young person comes to hospital in an emergency and mental health issues are clearly involved, how do we know how we can help them best? Health professionals can be unsure what to look for, what to do about they see, and how to judge how much they're helping the situation. Dr Joseph Manning MBE, a clinical academic nurse at Nottingham University Hospitals NHS Trust and NIHR lecturer at the University of Nottingham, is leading the SAPHE study which is researching how to make treatment of children and young people with mental health crises more effective and consistent. It's doing that by working **with** those children and young people. Joseph mentioned Prof Jane Coad, another of our researchers at Nottingham, and there's an interview with her coming up in and episode soon. Links SAPHE study website You can follow both @josephcmanning and Prof Jane Coad - @coadprofessor - on Twitter This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

About one in eight people in the UK have asthma attacks and researchers at the Nottingham Asthma Centre (part of Nottingham University Hospitals NHS Trust) are studying how to stop the early symptoms of an attack turning into a serious event. We need volunteers to help us research the different triggers and symptoms, so we can find new ways to treat the condition and reduce the use of steroid tablets, which can have undesirable side effects. This study is about recording your breathing and other signs - we are not testing any new treatments and your current treatment won't change. If you are interested in taking part in this study, please contact Karen Shaw or Rob Needham at the Nottingham Asthma Centre Karen Shaw or Rob Needham , or visit nuh.nhs.uk/research. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Alcoholism is one of the biggest factors in liver disease, and a dual diagnosis of alcoholism and mental health problems is very common - it's more than solely a physical illness - so understanding how to support people as they recover from alcoholism is a really important way to help cut liver disease. Mohsen Subhani is a clinical research fellow and a liver disease specialist at NIHR Nottingham Biomedical Research Centre, and he's the lead author on a newly published study in pulling together research on alcoholism and mental health in a new study. He and fellow researchers used a sample of eleven thousand studies to analyse the complicated interactions between mental health and alcoholism. Link to the study: https://doi.org/10.1371/journal.pone.0268034 This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

This interview with Professor Ana Valdes was done in February but we're only posting it now (in April) because it relates to a paper she co-authored which has only just been published in the Lancet Infectious Diseases. It's about covid and the Zoe app, and focuses on the omicron variant. Now government funding for the Zoe app's been stopped (though the app itself is still going strong) and omicron has been superceded by BA2, and in part thanks to this study, the official UK symptom list for covid has been updated. So as well as talking about the Lancet paper, I asked Professor Valdes about how viruses evolve over time and whether the laws of natural selection would tend to push them towards having less severe effects. But we started off with what made this study different to its predecessors. Links Zoe App Lancet article Prof Ana Valdes This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

The contents of your stomach may not seem to have much to do with skin cancer, but one of our studies seems to show that there are specific microbiome bugs which may be the key to treating melanoma more effectively with immunotherapy. Exactly how the microbiome helps us fight cancer is still a newish area of research and this study is one of the largest of its kind, with data from across the UK, the Netherlands, and Barcelona. It's just been published in Nature Medicine, and I talked to one of the authors, Amrita Vijay, who's a research fellow at the University of Nottingham. The Nature Medicine article is here (may need a subscription): https://www.nature.com/articles/s41591-022-01695-5 This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Good things come in small packages, as the saying goes, and this could certainly be applied to the sexual health research team at NUH. As well as seeing around 50,000 patients a year, they were the top recruiter in the trust in 2018, and have got over 150 patients on to a game-changing prophylaxis for HIV. Research and Innovation's Andrew Bennett caught up with Dr Ashini Fox, who's a consultant physician and research lead for the Sexual Health Team, and with Sarah Chadwick, who's Clinical Nurse Specialist and Research nurse.

Find out how we're breaking down the barriers to better health for women everywhere.

Research needs data and data needs - in the end - patients. Our researchers spend a lot of time Identifying the right patients for our studies, and more importantly, our patients spend a lot of time helping us. The more efficiently we can use the samples and other data they give us, the more we can help them. That's what the new Nottingham Bioresource is about - it pulls together samples and data from patients into one central bank, which is secure, controlled and confidential. Then we can help researchers identify the data they need, and let them access it in the most useful secure way possible. So everybody wins. That's the theory. To find out more, we talked to Jen Boston, Head of Research Governance and Quality at Nottingham University Hospitals NHS Trust, and to Natasha Hill, the bioresource operations manager - who explained how it's going to help researchers. If you would like to give us your views about the use of data and tissue samples in clinical research then you can join the conversation now on the Research InSight website: https://researchinsight.org.uk This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

One of the problems for treating gastro intestinal conditions is that it's hard to predict exactly how things dissolve in our guts. The food industry would dearly like to know more, and so would our gastro intestinal researchers, because if we knew how things fall apart in our colons, we can make drugs for conditions like Crohn's disease far more effective. But even with the latest imaging techniques that we use in Nottingham, it's difficult to see what's going on inside someone and for patients, it's uncomfortable. So - that's why we're use a mechanical colon, made by colleagues at @NIHRBhamBRC in Birmingham. Dr Luca Marciani, Professor in Gastrointestinal Imaging at Nottingham Biomedical Research Centre, told me about the project. This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

This week is #tinnitusweek, organised by @BritishTinnitus. But for the ten percent of the population who have the condition - every week is tinnitus week. I talked to @DrDavidBaguley, who's a Professor of Hearing Sciences at the University of Nottingham and heads up the Clinical Hearing Sciences group within the NIHR Nottingham Biomedical Research Centre (@hearingnihr), about the the research he and colleagues are doing into the condition. More information NIHR Nottingham Biomedical Research Centre hearing theme British Tinnitus Association and Tinnitus Week This Podcast is brought to you by the NIHR Nottingham Biomedical Research Centre. Follow us on @NottmBRC, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

How can you make a difference as a clinical researcher? University of Nottingham respiratory medicine professor and NHS consultant, Dominick Shaw, talks to Matt Hurst about the four things you need to when you're starting out. Read more on his blog post at 50 at 50: Standing on the shoulders of giants This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where ever you get your podcasts, and like/review us on Apple Podcasts especially. It's for Science.

How we make the most of their huge capacity for data, and processing, and artificial intelligence and the issues they might bring is actually the bit that is increasingly important these days, and this episode is a discussion about what Nottingham data scientists are doing in that area. You'll hear Phil Quinlan, who's the head of Digital Research Service at the University of Nottingham, and Associate Director at Health Data Research UK Dr Louise Bramley, Head of Nursing and Midwifery Research and Innovation at Nottingham University Hospitals Dr Sam Cox, who's a Senior Research Software Engineer at the University of Nottingham Grazziela Figueredo, a Senior Research Data Scientist at the university of Nottingham Hannah Jackson, who's an NIHR Pre Doctoral Clinical Academic Fellow - researches nursing informatics Nottingham University Hospitals, University of Nottingham and Health Research Data UK are launching a new discussion programme around the use of data in our research. Research Insight will be launched in January 2022 and will invite contributions from the public, patients, researchers and industry on developing safer ways of working with data, the best tools to support research projects and enabling innovation by use of data This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

For obvious and unavoidable reasons, all the research heroes experiences this year have been about dealing with Covid, but this particular hero had something else going on. Before Covid, Zoe Rose, was a research nurse in gastroenterology, but she was also coping with a personal tragedy of her own. Looking back on it now, she talks about how the intensity of the work during that first wave, and the help of a supportive team around her, help her find a way towards her own recovery. It's a really thoughtful and thought provoking interview, and Zoe talks very openly about her own mental health and how knowing she was able to help other people helped her. Now she works in the the Rapid Response Team, handling research across many specialisms at NUH - it's the R and I version of special forces. Content warning - there's some discussion of suicide in this episode. If you're affected by issues in the episode you can find help on: https://www.samaritans.org https://www.nhs.uk/mental-health/feelings-symptoms-behaviours/behaviours/help-for-suicidal-thoughts/ This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

'Big data' is often a bogeyman term, but at the start of the Covid-19 outbreak, reworking how we used data helped keep Nottingham University Hospitals NHS Trust running, and our radiologists were at the forefront of pioneering diagnostic techniques. Interviewees Dr Andrew Fogarty, NUH chest medicine physician and University of Nottingham epidemiologist Dr Mark Simmonds, who had just taken up to the role of divisional director for Medicine at NUH a few weeks before the pandemic struck Dr Iain Au-Yong, consultant radiologist at NUH Dr Tim Card, gastroenterologist at NUH gastroenterologist and University of Nottingham clinical epidemiologist They also mention two epidemiologists on the team from the University of Nottingham - Professor Joe West, and Professor Colin Crooks. You can listen to interviews with more of our leading scientists, clinicians and academics by subscribing to The Clinical Research Podcast on your favourite Podcast app. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

This week our guest is Professor Guru Aithal, Deputy Director of the NIHR Nottingham Biomedical Research Centre and a world-leading researcher in gastrointestinal and liver disorders. Professor Aithal talks to Matt Hurst from Research & Innovation about how science and his own personal experiences have shaped his views on why every researcher needs to build trust with ethnic communities. In a wide-ranging conversation Professor Aithal gives his perspective on the lasting legacy of historic unethical research practices, the impact of Black Lives Matter, COVID-19 vaccine hesitancy and health inequalities. He draws on his own research in the UK and in India into the impact of diet on gastrointestinal health and also the significant inequality in rates of premature death from liver disease in different populations. For more information about Professor Aithal's research please visit: www.nottinghambrc.nihr.ac.uk/research/gastrointestinal-liver You can listen to interviews with more of our leading scientists, clinicians and academics by subscribing to The Clinical Research Podcast on your favourite Podcast app. If you enjoyed this episode then please rate, review and subscribe. This will help others to find our Podcast and raise awareness of clinical research. Do it for the science.

Our guest this episode is Helen Navarra from the Children's Research Team at Nottingham University Hospitals NHS Trust. Helen is in conversation with Andrew Bennett and explains how COVID-19 changed everything for families taking part in clinical research at our hospitals. Helen herself is one of several members of the Children's Research Team, as well as the whole team and the work they did in partnership with the Cripps Health Centre in Nottingham, who received multiple nominations in our COVID-19 Research Heroes Awards last year. Helen explains the support they were able to give to children, young people and families which enabled them to take part in COVID-19 research. You can listen to interviews with some of our other COVID-19 Research Heroes, and many more people speaking about their research, by subscribing to The Clinical Research Podcast on your favourite Podcast app. This will help the work of heroes like the Children's Research Team get to a wider audience and to spread the word about research more generally. Thank you.

An introduction to a report on a joint project between Nottingham University Hospitals NHS Trust (and the Major Trauma Centre it hosts), and national charities Redthread and the Health Foundation. Violent crime victims are often caught up in a lifestyle that's going to see them returning to Nottingham's emergency department over and over again, often with more and more serious injuries. It's not just a healthcare issue, it's also about law and order, safeguarding and social care. But while we're treating their injuries, there's also a chance to break that repeated pattern. Nottingham University Hospitals sees a lot of victims of violence, partly because it's in a big city, but also because it hosts the Major Trauma Centre for the East Midlands region. We've been working with Redthread and the Health Foundation on how we can bring together healthcare, law and order, and social care, and we've just published a report on what we found. This report has been written independently under the guidance of The Health Foundation, an independent charity committed to bringing about better health and health care for people in the UK. Other links: The Health Foundation Redthread East Midlands Major Trauma Centre This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where ever you get your podcasts, and like/review us on Apple Podcasts especially. It's for science.

Kathryn Fairbrother is the new Head of Nursing for Research & Innovation at Nottingham University Hospitals NHS Trust. In this episode of The Clinical Research Podcast she talks about what inspired her as a nurse to get involved in clinical research and how she is hoping to now inspire other nurses - and healthcare professionals - to embark on their own research careers. Kathryn is in conversation with Matt Hurst from the Research & Innovation Communications Team. The Clinical Research Podcast is written and produced by the Research & Innovation team at Nottingham University Hospitals NHS Trust. To find out more about our research please visit: www.nuh.nhs.uk/research or follow us on Twitter @ResearchNUH. You can email us at: R&IComms@nuh.nhs.uk If you haven't already, please subscribe to the podcast where ever you get your podcasts, and like/review us as this helps other people to find our episodes. It's for science.

This episode's Research Hero is Laura Looby a children's clinical research nurse - normally. Fairly early on in the Covid outbreak it became clear that relatively few children were being affected so she was drafted to help with adult covid patients many of whom were at the other end of the age spectrum. She mentions 'dex' at one point. That's dexamethasone, one of the drugs trialled against Covid-19 early on, which turned out to be so effective it very quickly became part of the standard treatment. it's a really clear example of how research can lead to clinical treatment and researchers talk about it a lot. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

In the UK, about 1.3 million people are living with COPD - chronic obstructive pulmonary disease - , and there's no cure - but there's a lot of research into its treatment. In one type of COPD, emphysema, disease destroys alveoli in the lung so they can't transfer oxygen into the blood. It doesn't just mean there's less working lung, it means the now useless lung is taking up chest space so the patient can't inhale as deeply as they need to in order to get sufficient oxygen to the remaining working alveoli. So treatment often focuses on creating space in the chest so that patients can inhale more deeply - that means either surgery, or finding a way to make the emphysematic lung tissue take up less space. And either of those approaches have their own complications. Respiratory consultant Sam Kemp has recently joined Nottingham University Hospitals NHS Trust and part of his work is testing a new technique with the potential to help patients with condition, working with US company Pulmonx. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

Ask most people who they are, and they'll talk about their job, their likes and dislikes, their appearance. But there's another way of defining your identity - by the groups of people you mix with. We're a social species and who we choose to be with affects how we see the world, and ourselves. It can be a vital part of mental health. That's why occupational therapist and researcher Emilia Deakin chose to study how people with psychosis interact with the groups as they recover, for a study for her PhD, called UNFOLD. And then lockdown happened, and all of the normal social groups stopped. She told me how she solved the problem. As of August 2021, UNFOLD is still recruiting, so if you'd like to know more about it you can email emilia.deakin@nottingham.ac.uk. There's more infomation on the study website, https://www.researchintorecovery.com/research/unfold/ This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust with the NIHR Nottingham Biomedical Research Centre. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.