Podcasts about PBC

The Lord views His church in very unique and specific ways – like a body, like a family, as a bride. In this message, I look at the family aspect of God’s view of His church. Is it even possible to interact as the church of God if we are not embracing the family dynamic? …

Marcela Andrés serves as President and CEO of designEDengagement, PBC, a Latina-owned education consulting firm based in Texas on a mission to reimagine how educators, families, and community members partner to support the hopes and dreams of students. Previously, Marcela was a program director for a non-profit whose mission was to advocate for public education. She was also a third- and fourth-grade teacher at a bilingual elementary school.She is the author of Purposeful Educator Connections: Five Principles to Strengthen Relationships with Students. In the book, Marcela offers critical principles to deepen relationships with students, understand the importance of context beyond compliance, foster meaningful interactions, design high-quality learning environments, and partner with key stakeholders. Purposeful Educator Connections provides high-leverage practices, case studies, and reflection questions to help educators apply these principles to their practice, ultimately improving classroom culture and student outcomes.Takeaways: The discussion posits that zip codes should not determine an individual's destiny, emphasizing the importance of equity in educational opportunities. We assert that education is a non-linear journey, where each experience contributes uniquely to personal growth and career development. The podcast highlights the significance of educators in recognizing potential in students, often before they themselves are aware of it. We explore the crucial role of family and community engagement in the educational process, emphasizing that learning occurs beyond traditional classroom settings. The conversation underscores the necessity of self-care for educators, as their wellbeing directly influences their capacity to support students effectively. Lastly, we reflect on the transformative power of relationships in education, asserting that true learning flourishes in environments where individuals feel valued and seen. Websitehttps://www.designedengagement.com/Social Media InformationIG: https://www.instagram.com/molcajete_talk/LI: https://www.linkedin.com/in/marcelaandres/Show Sponsor – National Association for Primary Education (NAPE)https://nape.org.uk/Discover more about Education on Fire

The Bible tells us to let our moderation be known unto all men. What exactly does that mean? In a time of excessive appetites for activities like youth sports, careers, or hobbies, it is vitally important we understand what moderation is. In the same way the tires on a car need to be balanced to …

When the frontier was settled in the 1800s, it was common for the wagon trains to “circle the wagons” when under attack and at night for protection, safety and interaction. In this message, I look at how we should follow that example when we are attacked by Satan and faced with trials and tragedies. 06.22.25.Circle.the.Wagons.Tim.McCool

Main Street Meets the SuperCrowd: Why This Conversation MattersJen Risley, the powerhouse editor behind the Main Street Journal, joined me once again for our monthly livestream—an ongoing collaboration we've come to call Main Street Meets the SuperCrowd. These conversations are quickly becoming a cornerstone of community-building for our shared audience—readers who are hungry for smart, actionable ideas to strengthen local economies, invest with impact, and think more holistically about systems change.If you missed the livestream, let me offer a few highlights that made this session both thought-provoking and energizing.A Meeting of Minds, Not EchoesJen and I began by acknowledging how similar our respective platforms are in terms of mission and audience. But this isn't an echo chamber. Superpowers for Good and Main Street Journal approach the same problems from different angles, drawing on unique voices, frameworks, and solutions. That makes our collaboration not just refreshing, but necessary. As Jen put it, we're both “scurrying and collecting” a deep basket of ideas and stories from the grassroots—ensuring that the best thinking doesn't go unnoticed.Trade Policy Meets Local ImpactOne of the focal points of our conversation was an essay by Michael Shuman, the Publisher of the Main Street Journal, advocating for governors to consider using “negative tariffs” as a response to federal trade policy. Michael, a lawyer and economist, doesn't just write for impact—he writes with it. His provocative suggestion: states could effectively subsidize imports that benefit local economies, pushing back against protectionist tariffs that often do more harm than good.It's a bold concept, and while it drew criticism from at least one reader, we found the idea worth exploring. The critique—that tariffs protect American jobs—misses the macroeconomic reality Michael articulates so well: we simply don't manufacture like we used to. We're not bringing back a 1950s economy, no matter how much we may long for it. What we can bring back is strong worker representation, living wages, and economic dynamism—and those don't have to come from factories alone.In fact, we discussed how strong unions, not just strong industries, were the real drivers of middle-class prosperity in the postwar era. What if we had a powerful union of fast-food workers today? Imagine how that might reshape not just wages, but career pathways in the service economy.Rethinking Nonprofits: A Heated but Needed ConversationWe pivoted to another popular topic in Jen's world—a recent post arguing that nonprofits are, in many cases, the least effective vehicle for systemic social change. That headline alone sparked strong reactions, particularly among those with nonprofit roots (Jen included). But the conversation went beyond provocation.We examined the idea that nonprofits, for all their mission-driven focus, are structurally hampered by the need to chase grants and donors. This often means they spend more time fundraising than delivering on their mission. As Jen rightly pointed out, that dynamic saps not just time and energy but also local economic value.Michael's past reporting, including a 2005 Nation cover story co-authored with Marian Fuller, argues that even progressive nonprofits could do more by rethinking their business models. And we're seeing that today—especially with entities like OpenAI, which began as a nonprofit but now operates as a public benefit corporation (PBC), a structure that allows it to serve a mission while generating revenue and attracting capital.I pushed back just slightly—out of respect for the enormous good nonprofits have done. Since the time Michael and I were born, global poverty has dropped from over 50% to roughly 10%. That's not magic. That's decades of nonprofit work on health, education, and development. But when it comes to economic development—whether in Nairobi or Nebraska—it's hard to deny that mission-driven businesses may have more horsepower than nonprofits constrained by annual fundraising cycles.Return on Integrity: Why We Invest LocalWe wrapped up by talking about a post I wrote recently: “25 Reasons to Invest Through Regulated Crowdfunding for Social Change.” Jen highlighted two that especially resonated with her. First, the power of recirculating dollars within a local economy. When a dollar is spent at a locally owned business, it circulates far more than a dollar sent to a national chain or an online platform. That's not just economics—it's a theory of change.Second, Jen was struck by how regulated crowdfunding creates fertile ground for first-time investors. She herself started with a small investment—just $96—in The Super Crowd, Inc. That entry point matters. It lowers the barriers for ordinary people to participate in building the future they want to see. When investing is local, transparent, and accessible, it ceases to be the domain of Wall Street insiders and becomes a tool for anyone with $100 and a dream.She also reminded us of a phrase I like to use: return on integrity. Impact investing isn't just about profit—it's about aligning your values with your money. It's about sleeping better at night because you're helping your neighbor launch a food truck or keep a childcare center open.A Better Future with Better ToolsOne other update I shared: we've launched a new due diligence tool for paid subscribers. Jen tested it out and found it easier and faster than our earlier prompt-based tool. While it doesn't replace the full depth of a long-form analysis, it provides a meaningful synthesis of a company's Form C—highlighting deal terms, risks, and key facts that too often go overlooked. This is especially important for newcomers who may be investing in a local business for the first time.As I said during the livestream, we're continuing to refine this tool. The goal is to build something that delivers the insight of a 20-hour research process in just 5 to 10 minutes—and makes it either free or radically affordable. That's how we grow the movement.Join the MovementThat word—movement—kept surfacing throughout our conversation. This isn't just a monthly chat. It's not just two newsletters. It's part of a broader, rising effort to put capital in the hands of people building our communities—people often excluded from traditional finance.So if you haven't yet subscribed to both publications, I'll make this pitch one more time: do it. Superpowers for Good is just $5.95/month or less with an annual plan. Main Street Journal offers insights you won't find anywhere else. For the price of one streaming service, you can subscribe to both and get a stream of ideas that actually build the future.Until next month, keep investing with your values, keep amplifying local voices, and keep believing in the power of the crowd. Get full access to Superpowers for Good at www.superpowers4good.com/subscribe

In this episode, Dr Gideon Hirschfield meets with patient advocate Jess Schnur to discuss challenges related to the diagnosis and management of primary biliary cholangitis (PBC) to provide actionable strategies for healthcare professionals to incorporate into patient care, including:Disease concerns and frequently asked questions from a patient perspectiveManaging symptomsTreatment options and supportive careImportance of awareness and educationPresenters:Gideon Hirschfield, MA, MB BChir, FRCP, PhDLily and Terry Horner Chair in Autoimmune Liver Disease ResearchProfessor, Division of Gastroenterology and HepatologyUniversity of TorontoDirector, The Autoimmune and Rare Liver Disease ProgrammeDirector, Francis Family Liver ClinicToronto General Hospital, University Health NetworkOntario, CanadaJess N. Schnur, BSN-RNNational PBC Patient AdvocateAmerican Liver FoundationDonation Support Services CoordinatorLifeline of OhioColumbus, OhioTo learn more, see the programHear Me: Patient Perspectives on PBC

In this podcast, Sonal Kumar, MD, MPH, meets with patient advocate Maria Morais to discuss actionable steps that healthcare providers can incorporate into the care of people with primary biliary cholangitis (PBC). Listen as they discuss:The chronic nature of PBCGoing beyond biochemical markers to assess and address symptoms such as fatigue and pruritusThe importance of referral to patient support groupsPresenters:Sonal Kumar, MD, MPHAssistant Professor of MedicineDirector, General Gastroenterology and HepatologyWeill Cornell Medical CollegeNew York, New YorkMaria G. Morais, RNVP Patient AdvocacyCanadian PBC SocietyToronto, CanadaTo learn more, see the programHear Me: Patient Perspectives on PBC

In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau discuss an illustrative patient case to demonstrate how they individualize primary biliary cholangitis (PBC) therapy for patients ​with cirrhosis. Topics covered include:AASLD guideline recommendations for second-line therapy for PBCConsiderations when using newer agents for second-line treatment of PBC in patients with cirrhosis: elafibranor and seladelparPresenters:Stuart C. Gordon, MD Professor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford HealthDetroit, MichiganNancy Reau, MD Professor of MedicineRichard B. Capps Chair of HepatologyChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRush University Medical CenterChicago, IllinoisTo learn more about PBC management, check out our program, Curbside Consults: Expert Insights on Challenges in PBC Management.Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau, use an illustrative patient case to explore the roles of ALP and other biochemical markers in PBC management, and explain what to expect from treatment. Topics covered include: How baseline ALP can affect ALP normalization after second-line treatment with elafibranor and seladelparPotential outcomes if ALP normalization cannot be achievedThe importance of managing fatigue, pruritus, and sleep disturbances independently of the biochemical responsePresenters:Stuart C. Gordon, MDProfessor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford HealthDetroit, MichiganNancy Reau, MDProfessor of MedicineRichard B. Capps Chair of HepatologyChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRush University Medical CenterChicago, IllinoisTo learn more about PBC management, check out our program, Curbside Consults: Expert Insights on Challenges in PBC Management. Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

¡CANELO ADVIERTE A CRAWFORD!CHAVEZ JUNIOR REGRESA A DEFENDER SU LEGADO ANTE JAKE PAUL!¡FRANCISCO “CHIHUAS” RODRIGUEZ SE CORONO CAMPEON INTERINO DE PESO MOSCA PRO EL CMB!¡EL“CAMARÓN” ZEPEDA SE PREPARA PARA ENFRENTAR A SHAKUR!¡4 MEXICANOS CONTINUAN CON VIDA EN EL GRAND PRIX DE BOXEO!¡RECORDAREMOS “AL ASESINO DE MANASSA” JACK DEMPSEY EN SU NATALICIO!

The Bible gives multiple accounts of the dead being raised back to life in this world, but that is not the only type of resurrection we find in the scriptures. We read about our spiritual man being resurrected back to life with the new birth and about the resurrection of our bodies eternally at the end …

Primární biliární cholangitida neboli PBC je chronické onemocnění, které postupně ničí malé žlučovody a vede k fibróze a cirhóze jater nebo až k úplnému selhání tohoto orgánu. Řada lékařů ji proto zaměňuje za následky nadměrného pití alkoholu. Existuje přitom několik účinných léků – včetně dvou nových. Víc o problematice s doc. MUDr. Soňou Fraňkovou, Ph.D., zástupkyní přednosty pro klinickou hepatologii Kliniky hepatogastroenterologie IKEM. 

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• La muestra “b” de Jaime Munguía resulto positiva y ahora el mexicano espera la resolución de la Junta Británica de Control de Boxeo. • ¡Canelo y Crawford presentan su pelea en Riad! Se confirma como sede el Allegiant Stadium el mexicano nuevamente inaugurará en Las Vegas una locación para el pugilismo. • En exclusiva nos acompañan Eduardo “sugar” Nuñez, Armando “toro” Resendiz y Wilibaldo “sullo”garcia. • referee y jueces por parte de la Comisión Atlética de Nevada para los frentes de la cartelera Pacquiao-Barrios! • El presidente del Consejo Mundial de Boxeo, Mauricio Sulaimán, llegó a Arabia Saudita para presenciar la segunda fase del Grand Prix de Boxeo. El evento se celebrará este fin de semana en la ciudad de Riad con la participación de 64 peleadores en distintas divisiones. • también recordaremos la trayectoria del icónico Roberto “manos de piedra “Duran en su cumpleaños número 74

How do you decide when to move from first-line to second-line treatment for primary biliary cholangitis (PBC)? In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss this question and more, including:How and when to measure treatment responseEvidence-based goals of therapyConsiderations for second-line treatmentNew agents for second-line treatment: PPAR agonistsPresenters:Alan Bonder, MD, AGAFAssociate Professor of MedicineMedical Director of Liver TransplantDepartment of GastroenterologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolBoston, MassachusettsAparna Goel, MDAssociate Clinical Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaContent based on an online CME program supported by independent educational grants from Gilead Sciences, Inc., and Ipsen Biopharmaceuticals, Inc​.To learn more about PBC management, check out our program, Curbside Consults: Expert Insights on Challenges in PBC Management.Supported by educational grants from Gilead Sciences, Inc. and Ipsen Biopharmaceuticals, Inc

In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss how they assess the symptoms of primary biliary cholangitis (PBC) and explore how new therapeutic agents may help alleviate symptom burden. Topics include:Strategies and tools for assessing pruritusNonpharmacologic and pharmacologic management of pruritusSecond-line agents and their impact on pruritusInvestigational treatments for pruritusPresenters:Alan Bonder, MD, AGAFAssociate Professor of MedicineMedical Director of Liver TransplantDepartment of GastroenterologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolBoston, MassachusettsAparna Goel, MDAssociate Clinical Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaContent based on an online CME program supported by independent educational grants from Gilead Sciences, Inc., and Ipsen Biopharmaceuticals, Inc​.To learn more about PBC management, check out our program, Curbside Consults: Expert Insights on Challenges in PBC Management.

Are women being sold a myth about fitness during menopause? Michelle MacDonald sits down with Dr. Allan Bacon—a former surgeon turned physique coach—for a frank, science-backed conversation on women's health and fitness, the damaging fads targeting midlife women, and the importance of cultivating a healthy mindset over quick fixes. They explore the psychological traps of crash diets, the false promises of hormone-focused programs, and the influence of social media pseudoscience. Dr. Bacon breaks down how personal growth comes from evidence-based training, not magical shortcuts, and offers empowering truths about body composition, strength training, and navigating menopause with resilience and logic.Leave a rating for this podcast with one click https://ratethispodcast.com/michellemacdonald  WHAT TO LISTEN FOR0:38 Why Smart Women Fall for Fitness Fads3:14 Menopause Marketing A Feeding Frenzy11:44 Just Lift Heavy The Most Misleading Advice13:29 Do Men and Women Build Muscle the Same20:32 Age-Related Muscle Loss What's Really Happening28:22 Women Are Not Large Mice32:39 The SWAN Study Hope for Midlife Women GUEST: DR. ALLAN BACON, DDS, CPT, PBC, USAPL-CC, CNC, PN1Website | Instagram | YouTube | Facebook GroupCONNECT WITH MICHELLEWebsite | Instagram | YouTube | Facebook | X

Matt and EzRaw discuss the latest in boxing news including:News and NotesOscar De La Hoya says the media is bought and paid for and won't write and talk about certain newsOscar De La Hoya says Eddy Reynoso needs to be investigated?Oscar De La Hoya says Canelo vs Crawford will be during the day and not in prime timeOscar De Hoya states Golden Boy, PBC, and Matchroom are all working together to make fights and are not going anywhereTeofimo Lopez wears a PBC hat on his Instagram story with the date 8-16Turki Alasheik states he doesn't want anymore Tom and Jerry fightsJake Paul states he thinks Anthony Joshua, Ryan Garcia, and Canelo Alvarez are the most overrated boxersEddie Hearn says Turki does all the promotional ideas for his events and everyone else takes a back seatEZ Money Parlay of the Day, EzRaw Report Card, EzRaw BreakdownEzRaw BreakdownHitchins vs Kambosos Wardley vsHuni Mason vsNakathaliaEzra's Raw Hard CashMike's EZ moneyMatt's Best Bet.Rumor ReportQuick HitsOscar “La Migraña” Duarte vs. Kenneth “Bossman” Sims Jr. 8/2/25.Nonito Donaire return tonight vs Andres Compos -Souleymane Cissokho has officially been named the mandatory challenger to the winner of the July 19, PBC PPV on Prime bout between Mario Barrios and Manny Pacquiao.The winners of Rey Vargas vs. Carlos Castro and Bruce Carrington vs. Mateus Heita must fight each other afterThe WBC will order a bout between Interim WBC Junior Middleweight Champion Vergil Ortiz and Serhii Bohachuk. Ortiz previously defeated Bohachuk in August 2024.Edwin De Los Santos and Sampson Lewkowicz have agreed to mutually part waysFilip Hrgovic vs. David Adeleye 8/16 in SaudiThe WBO has officially ordered negotiations between Sam Noakes and Abdullah Mason for the vacant WBO Lightweight Championship. Parties have 20 days to reach agreement.Alan David Picasso vs. Kyonosuke Kameda on July 19 at the MGM Grand Garden Arena in Las Vegas as part of #PacquiaoBarriosKenshiro Teraji vs. Ricardo Sandoval, Antonio Vargas vs. Daigo Higa, Erick Rosa vs. Kyosuke Takami#MrOneTake's One TakeRead the latest news at Brunch BoxingThoughts or questions? Email us at brunchboxingqa@gmail.comHosts: Matt, and EzRawSocial: MikeProducer: Huey

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It is easy to lose heart in the face of evil. Sometimes the evil that affects us can be distant – like being frustrated with politics. But sometimes it touches us directly. When it touches us directly, we need to prepare our minds to know how the Lord views and deals with such evil, as …

(0:00) Intro (1:49) About the podcast sponsor: The American College of Governance Counsel(2:36) Introduction by Professor Anat Admati, Stanford Graduate School of Business. Read the event coverage from Stanford's CASI.(4:14) Start of Interview(4:45) What inspired Karen to write this book and how she got started with journalism.(8:00) OpenAI's Nonprofit Origin Story(8:45) Sam Altman and Elon Musk's Collaboration(10:39) The Shift to For-Profit(12:12) On the original split between Musk and Altman over control of OpenAI(14:36) The Concept of AI Empires(18:04) About concept of "benefit to humanity" and OpenAI's mission "to ensure that AGI benefits all of humanity"(20:30) On Sam Altman's Ouster and OpenAI's Boardroom Drama (Nov 2023) "Doomers vs Boomers"(26:05) Investor Dynamics Post-Ouster of Sam Altman(28:21) Prominent Departures from OpenAI (ie Elon Musk, Dario Amodei, Ilya Sutskever, Mira Murati, etc)(30:55) The Geopolitics of AI: U.S. vs. China(32:37) The "What about China" Card used by US companies to ward off regulation.(34:26) "Scaling at All Costs is not leading us in a good place"(36:46) Karen's preference on ethical AI development "I really want there to be more participatory AI development. And I think about the full supply chain of AI development when I say that."(39:53) Her biggest hope and fear for the future "the greatest threat of these AI empires is the erosion of democracy."(43:34) The case of Chilean Community Activism and Empowerment(47:20) Recreating human intelligence and the example of Joseph Weizenbaum, MIT (Computer Power and Human Reason, 1976)(51:15) OpenAI's current AI research capabilities: "I think it's asymptotic because they have started tapping out of their scaling paradigm"(53:26) The state (and importance of) open source development of AI. "We need things to be more open"(55:08) The Bill Gates demo on chatGPT acing the AP Biology test.(58:54) Funding academic AI research and the public policy question on the role of Government.(1:01:11) Recommendations for Startups and UniversitiesKaren Hao is the author of Empire of AI (Penguin Press, May 2025) and an award-winning journalist covering the intersections of AI & society. You can follow Evan on social media at:X: @evanepsteinLinkedIn: https://www.linkedin.com/in/epsteinevan/ Substack: https://evanepstein.substack.com/__To support this podcast you can join as a subscriber of the Boardroom Governance Newsletter at https://evanepstein.substack.com/__Music/Soundtrack (found via Free Music Archive): Seeing The Future by Dexter Britain is licensed under a Attribution-Noncommercial-Share Alike 3.0 United States License

• ¡Ya es oficial canelo – Crawford pelearan el 13de septiembre en las vegas, así lo confirmó el tio turki!• A un mes de su regreso al boxeo profesional Manny Pacquiao es inducido al salón de la fama del boxeo…• En exclusiva el pac man nos abrió las puertas de su campamento…• A horas de conocer el resultado de la prueba “B” Mauricio Sulaiman presidente del cmb apoya a Jaime Munguia…• ¡Tras sy retiro recordaremos los mejores momentos de la carrera de Vasily Lomachenko!

#teofimolopez #gervontadavis #premierboxingchampions ThaBoxingVoice dives into the sizzling rumor: Has Teofimo Lopez Jr., the WBO junior welterweight champ, signed with Premier Boxing Champions? We unpack the buzz from X posts, including Lopez's PBC hat video with the '8.16' date, his plan to fight the Davis-Roach winner, and a fan's backlash over his racist remarks. Is this a new era for “The Takeover,” or just hype? Join us as we debate Lopez's next move, analyze his Times Square win, and explore PBC's stance. With exclusive insights, fan polls, and spicy takes, this episode is a must-listen for boxing fans craving the latest on this polarizing star. Tune in, vote, and let your voice be heard!

In this message, I look at the prayer of true pastors – that the people he preaches to will stand in the truths they are taught. 06.01.25.A.Pastors.Prayer.Tim.McCool.mp3

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#mannypacquiao #mariobarrios #premierboxingchampions Step into the ring with ThaBoxingVoice as we unpack the potential collapse of Premier Boxing Champions (PBC) with their Amazon Prime Video deal on the ropes. Why is PBC's PPV-heavy model driving fans away? With ESPN out after parting with Top Rank, and Netflix and Riyadh Season stealing the spotlight, what's next for stars like Gervonta “Tank” Davis? Joined by boxing insider Blake Avignon, we break down recent bouts, financial rumors, and boxing's shifting streaming landscape. Expect unfiltered takes, fan polls, and bold predictions on whether PBC can dodge a knockout. A must-listen for boxing fans craving the truth behind this pivotal moment! Subscribe now!

Everyone is looking for happiness. Being happy is a wonderful way to feel. But the reality of life is that happiness can be difficult to achieve and more difficult to hang onto. In this message, I look at how to find happiness in the context of Peter’s clear teaching on discipleship. 05.28.25.How.to.Find.Happiness.Tim.McCool

• ¡EDDY REYNOSO SOLO ENTRENA A MUNGUIA, EL NO ES RESPONSABLE MAS QUE, DE LO DEPORTIVO, SAUL ALVAREZ• ¡ARMANDO RESENDUZ DA LA CAMPANADA Y SE CORONA CAMPEON INTERINO EN 168 LIBRAS!• ¡MANNY PACQUIAO Y MARIO BARRIOS PRESENTARON SU PELEA EN ESTADOS UNIDOS!• HABRA REVANCHA ENTRE NAVARRETE Y CHARLY SUAREZ!• PITBILL CRUZ VS TASHIRO FIERRO PARA EL 19 DE JULIO• ¡A NUEVE AÑOS DE SU PARTIDA, RECORDAREMOS LA VIDA DE MUHAMMAD ALI!

Jesus tells us that in order for a man to find his life he must first lose it. That might seem like an unusual statement if we only look at it from a superficial perspective. In this sermon, Brother Luke looks at the life of Paul to get a better understanding of what it means …

Erin Blanchfield learned minutes before walkouts that Maycee Barber dropped out of the UFC Vegas 107 main event. LT and BC go over the circumstances regarding the last-minute cancellation and what this means for Barber's future. Also, what is next for Blanchfield? The fellas go over the rest of the card including Mateusz Gamrot's impressive win against Ludovit Klein. And Ramiz Brahimaj and Dustin Jacoby both notched first-round wins. Plus, the guys go over the results from the PBC card, news about a location change for Noche UFC and a look at this weekend's UFC 316 event.See omnystudio.com/listener for privacy information.

#PlantResendiz #CharloLaManna #calebplant On this explosive episode of #TBVPodcast, Thaboxingvoice dives into the May 31, 2025, PBC on Prime Video card from Las Vegas! We break down Caleb Plant defending his WBA interim super middleweight title against Armando Resendiz in a 12-round clash. Jermall Charlo returns against Thomas LaManna in a 10-round super middleweight bout, setting up a potential Plant showdown. Plus, we preview Yoenli Feliciano Hernandez vs. Kyrone Davis and Isaac Lucero vs. Omar Valenzuela. Join us for expert analysis, bold predictions, and the latest boxing buzz!

In the series from I Thessalonians, I look at a statement made by the Apostle Paul. He says that the church at Thessalonica was appointed to afflictions. When we are in the fire of afflictions, the heat shows what is in our heart. In this message, I look at how we face affliction and how …

Everyone agrees that the plant you grow will always be the same as the seed you plant. Corn seeds don’t yield apple trees. The Bible is clear that we will reap what we sow. If we sow to the flesh we will reap destruction. Our problem as children of God is not a lack of understanding this, but it comes …

Another weekend and another shocker main event, as Caleb Plant was upset in Las Vegas. We discuss that bout, the undercard and also fight cards for Golden Boy Promotions and Matchroom Boxing from Friday on the latest "Fight Freaks Unite Recap Podcast."Host T.J. Rives and insider Dan Rafael of his Fight Feaks Unite Substack and newsletter are back.The discuss.The PBC on Prime Video card Saturday in Las Vegasas little known Armando Resendiz upset Caleb Plant and wins the WBA interim 168 lb. title. Is this more verifcation that Plant's better days are behind him? And what does it do to the possible fight with super middleweight Jermall Charlo, who scored a TKO6 over Thomas "Cornflake" LaManna.They also talk the middleweight Yoenli Hernandez decisioning Kyrone Davis and also, junior middleweight Isaac Lucero with a quick TKO over Omar Valenzuela. Next a recap of the Golden Boy DAZN main event Friday in Las VegasSuper middleweight Bektemir Melikuziev wins a tremendous decision over Darius Fulghum in a WBA eliminator. More on this bout.Plus, there was a solid Matchroom DAZN card Friday in Guadalajara, MexicoLight heavyweight Khalil Coe TKO6 over Manuel Gallegos in a rematch and avenges his TKO loss. And, junior featherweight Murodjon Akhmadaliev earns a TKO8 against Luis Castillo and up next is Sept. 14 Naoa Inoue challenge for the undisputed 122 lb. belts.Some NewsDevin Haney-Teofimo Lopez back ON for Aug. 16th after Teofimo apologized to Turki Alashikh.The Manny Pacquiao-Mario Barrios full PPV undercard wsa announced Saturday in Vegas and the fighters met briefly with the media.Sadly, Hall of Famer Mike McCallum died in Las Vegas at age 68. One of the greats! He won titles at 154 lb., 160 lb., and 175 lb. We reminisceNostalgiaJune 1, 2019 – 6 years ago Sunday – late replacement opponent Andy Ruiz TKO7 Anthony Joshua in a massive upset to win the unified WBO/IBF/WBA heavyweight title in their first fight. Big Dan ringside at MSG. (Watch more on this huge upset on our Big Fight Weekend Youtube page)Hear it all on the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!

Instant Reaction to Armando Resendiz' split decision win over Caleb Plant t win the WBA Super Middleweight Title. Plus a full breakdown on the PBC on Prime card.#ArmandoResendiz #plantreséndiz@toro_resendiz1 @premierboxing

Dr. John Sweetenham shares highlights from Day 3 of the 2025 ASCO Annual Meeting, including new research for the treatment of advanced renal cell carcinoma and 2 studies on novel approaches in non-small cell lung cancer. Transcript Dr. John Sweetenham: Hello, I'm Dr. John Sweetenham, the host of the ASCO Daily News Podcast, with my takeaways on selected abstracts from Day 3 of the 2025 ASCO Annual Meeting. Today's selection features studies addressing the treatment of advanced renal cell carcinoma and 2 studies exploring novel approaches in non-small cell lung cancer. My disclosures are available in the transcript of this episode. The first abstract is number 4505. This study, led by Dr. Toni Choueiri of the Dana-Farber Cancer Institute, describes the final analysis of the CheckMate 214 trial, which compared the combination of nivolumab and ipilimumab with sunitinib for the first-line treatment of advanced renal cell carcinoma. The ipi-nivo combination is approved for the frontline treatment of intermediate and poor-risk advanced renal cell carcinoma based on the primary analysis of the CheckMate 214 trial, which demonstrated a higher response rate and longer overall survival compared with sunitinib. Today's presentation provided the final safety and efficacy results for the trial with long-term follow-up of more than 9 years.  The intent-to-treat (ITT) population in this trial comprised 550 patients randomized to nivo and ipi versus 546 who received sunitinib. The final analysis showed sustained long-term benefit for the combination therapy. Patients given nivolumab plus ipi had a 29% reduction in the risk for death compared with sunitinib. For patients with intermediate or poor-risk disease, there was a 31% reduction in the risk of death.   The probability of remaining in response through 8 years was more than doubled with nivolumab plus ipilimumab versus sunitinib in the ITT population at 48% versus 19%, and in the intermediate and poor-risk population at 50% versus 23%. The other important observation is that patients with favorable-risk disease appeared to have a 20% reduction in the risk for death at 9 years and more durable responses. This suggests a possible delayed benefit for ipi and nivo in this group since these differences were not seen in the earlier analysis.   No new safety signals emerged with longer follow-up, and the results confirm the use of ipi and nivo as a standard front-line combination therapy in this disease. Since this combination has been in widespread use for some years, the results are not surprising although the subgroup analysis suggesting benefit in favorable-risk patients is likely to inform practice in the future.   Today's second abstract is number is 8506, which was presented by Dr. Tony Mok from the Chinese University of Hong Kong, describing results from the phase 3 HERTHENA-Lung02 trial. This trial compared the antibody-drug conjugate patritumab deruxtecan with platinum-based chemotherapy in patients with EGFR-mutated advanced non-small cell lung cancer following a third-generation tyrosine kinase inhibitor (TKI).  Patritumab deruxtecan, also known as HER3-DXd, comprises a fully human anti-HER3 IgG3 monoclonal antibody conjugated to a topoisomerase 1 inhibitor payload, and showed activity in a previous phase 2 trial in patients relapsing after EGFR TKI and chemotherapy.   In this phase 3 study, this agent was compared with platinum-based chemotherapy in eligible patients with an EGFR-activating mutation who had previously received 1 or 2 EGFR TKIs, at least one of which was a third-generation drug, with relapse or progression after this therapy. Five hundred and eighty-six patients were enrolled, with progression-free survival as the primary endpoint.  The primary analysis showed a 9-month progression-free survival of 29% for the experimental arm compared with 19% for platinum-based chemotherapy, for a hazard ratio of 0.77 and a P value of 0.011. With higher progression-free survival rates at 6 months and 12 months, HER3-DXd also had a better objective response rate (35.2% versus 25.3%) compared with platinum-based chemotherapy (PBC), and HER3-DXd also extended intracranial progression-free survival compared with PBC in patients with brain metastases, with a hazard ratio of 0.75. Grade 3 or more treatment-related adverse events occurred in 73% of patients treated with HER3-DXd and 57% of patients who received PBC. HER3-DXd had a higher rate of grade or more 3 thrombocytopenia, and drug-related interstitial lung disease occurred in 5% of patients in the HER3-DXd arm.   The follow-up will need more time to mature since no overall survival data are currently available, but definitely an agent to watch with interest. Moving on to today's final abstract, 8500, was presented by Dr. Pasi Jänne from the Dana-Farber Cancer Institute, describing results from the phase 2 portion of the KRYSTAL-7 study. This study is exploring the use of a potent KRAS inhibitor, adagrasib, in combination with pembrolizumab in patients with advanced or metastatic KRASG12C- mutated non-small cell lung cancer.  Adagrasib has already received accelerated approval in the U.S. for previously treated locally advanced or metastatic NSCLC with a KRASG12C mutation. A previous report from the KRYSTAL-7 study demonstrated encouraging activity in combination with pembrolizumab in the frontline setting for this patient group who also had more than 50% expression of PD-L1. The presentation today described efficacy and safety data for this drug combination across all PD-L1 expression levels.  One hundred and forty-nine patients with a median age of 67 years were treated with the combination, 104 of whom had PD-L1 expression level results available, representing the so-called biomarker population in this trial. The overall response rate for the entire study population was 44%. In the biomarker population, the overall response rate ranged from 36% in those with less than 1% PD-L1 expression to 61% for those with more than 50% expression. For all patients, the median response duration was just over 26 months, and the median progression-free and overall survival rates were 11 and 18.3 months respectively.    For the biomarker population, the median progression-free and overall survival were highest in those patients with more than 50% PD-L1. No new safety issues emerged from this analysis; the most frequent toxicities were nausea, diarrhea, and increases in transaminases. Immune-related toxicities included pneumonitis, hypothyroidism, and hepatitis. These are important results and the results of the phase 3 portion of KRYSTAL-7, which compares first-line therapy with adagrasib plus pembro versus pembro alone in the KRASG12C mutated/PD-L1 more than 50% group, will be informative. For those patients with lower levels of PD-L1 expression, the authors suggest that the treatment escalation may be beneficial, possibly including the addition of chemotherapy.  That concludes today's report. Thanks for listening and I hope you will join me again tomorrow to hear more top takeaways from ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts.  Disclaimer:  The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  Find out more about today's speaker:    Dr. John Sweetenham    Follow ASCO on social media:     @ASCO on Twitter    @ASCO on Bluesky    ASCO on Facebook    ASCO on LinkedIn     Disclosures:   Dr. John Sweetenham:    No relationships to disclose

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Luke Thomas, Brian Campbell and the Morning Kombat crew are back on a Friday to preview this weekend's UFC Fight Night featuring Erin Blanchfield vs. Maycee Barber. The fellas go through the latest boxing headlines including PBC previews of Caleb Plant vs. Armando Resendiz and Jermall Charlo vs. Thomas Lamanna. Plus, Teofimo Lopez going after Turki Alalshikh in a social media outburst costs him. What do LT and BC make of the latest antics from Lopez? And the UFC might make a return to ESPN. Will it go over well with the fanbase? Happy Friday Donks!See omnystudio.com/listener for privacy information.

Most of the rhetoric today uses the second coming of Christ to strike fear in our minds. If a preacher says, “Are you ready for His coming?”, it usually refers to making sure you are eternally saved, so when He shows, you will be ready in that way. But the Bible teaches eternal salvation is …

A familiar fighter returns to the Las Vegas limelight, plus, some prominent fighters are in the news for the wrong reasons and we explain it all on the newest "Big Fight Weekend Preview Podcast."Host T.J. Rives and insider Dan Rafael are back aboard to go over everything.They begin with:A Recap of the Ohashi Promotions card on Wednesday in Yokohama, JapanYoshiki Takei TKO1 Yuttapong Tongdee and retains WBO bantamweight title.Plus, Eduardo Nunez wins easily in 12 rounds over Masanori Rikiishi and wins the vacant IBF junior lightweight title. Dan has a lot on both Next, a Preview of the PBC on Prime Video card Saturday night at Mandalay Bay in Las VegasCaleb Plant returns against little known. Armando Resendiz, 12 rounds, for Plant's WBA interim super middleweight title. More importantly is he's likely fighting Jermall Charlo next. Charlo first takes on. Thomas LaManna in a 10 rounds super middleweight bout. The boys discuss.NewsJaime Munguia tested positive for foreign testosterone in his system in a VADA test related to his May 3rd rematch win over Bruno Surace. What's going to happen now and does Surace get the no-contest ruling?  Dan has more on his reporting on the supposed Aug. 16 Teofimo Lopez-Devin Haney agreed to bout, but fight falling apart over Lopez's tweet storm in which he insulted Turki Alashikh. WHAT ARE WE DOING HERE?!Ryan Garcia undergoes right hand surgery, and the plans for Fall fight in limbo for now.Top Rank July 26th card officially announced, Xander Zayas-Jorge Garcia for vacant WBO junior middleweight title & featherweight Bruce “Shu Shu” Carrington vs. Mateus Heita for the vacant WBC interim title in the co-featureYudai Shigeoka, the former WBC strawweight titlist, posted to social media on Thursday to provide an update on older brother and former IBF strawweight titlist Ginjiro Shigeoka, including that he is breathing on his own.NostalgiaWe encourage you to find our Youtube page for some thoughts on HOFer Johnny Tapia, a fan favorite, who died back on May 27, 2012 – 13 years ago on Tuesday.Meanwhile, for all our podcat content keep it locked in on this feed on Apple/Spreaker/Spotify, etc.! 

King David desired to bring the ark of the covenant home to his new house in Jerusalem. This was a good thing. But the way David went about it, displeased the Lord. How many times do we have issues we deal with, and we go about it the wrong way? In this message, I look …

We play catch up with the reports surrounding Turki and his plans for Canelo-Crawford and Teofimo's beef with him. And we look to the PBC on Prime weekend card.

In the first message of our recent annual meeting, Elder Tim Lawrence of Bethel PBC near Nashville, preaches about sticking to the script, or scriptures. The Lord has preserved for us in His Word everything we need to know about Him and about how to navigate the pitfalls of this fallen world. 05.03.25.Sticking.to.the.Script.Tim.Lawrence

In the final message of the May meeting, Elder Graham Sims speaks about the ways in which the Lord restores vision. Sometimes it can be in a physical way like Jesus did with the blind, but sometimes it can be spiritual vision. 05.04.25.Restoring.Vision.Graham.Sims

Have we been affected by worldwide deceptions like global warming or evolution? Or have we been affected by lying? Or what about slander or gossip? Have we experienced personal attacks during opportunities to minister? Have we ever dealt with betrayal? Have we refused to forgive others? Has our family been attacked in some way? Has …

On this edition of the show, insider Dan Rafael is one on one with former IBF world super middleweight champ Caleb Plant.Plant, who defends the WBA's "interim super middleweight title" against Armando Resendiz in the main event of the PBC on Prime Video card on May 31 in Las Vegas, is looking to set up a fight later in the year against Jermall Charlo. Charlo is returning from a long layoff in the co-feature.They covered a variety of topics including, Caleb being in the ring with Canelo Alvarez in an undisputed 168 lb. title bout in 2022 and whether, he believes there could be a rematch down the line or not?It's all on this special edition of the "Fight Freaks Unite Podcast" on this feed and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!And, also SEE this interview on our Big Fight Weekend Youtube page!

Discover how to recognize the burden of primary biliary cholangitis (PBC)-associated pruritus and make evidence-based treatment decisions to improve patient quality of life. Credit available for this activity expires: 5/22/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/breaking-news-what-youre-itching-know-about-primary-biliary-2025a1000clq?ecd=bdc_podcast_libsyn_mscpedu

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It's another lighter weekend of action, although there is a prominent world title on the line in the Far East. We go over the matchups and have plenty of news, including Manny Pacquiao confirming his return and more on the "Big Fight Weekend Preview Podcast"Host T.J. Rives returns with insider Dan Rafael to go over it all on this edition.They start with the preview of the Queensberry DAZN card Saturday in Glasgow, ScotlandFormer undisputed 140 lb. champ Josh Taylor is back meeting a little known fighter in Ekow Essuman, in a welterweight clash. Does Taylor have anything left?Also, promising heavyweight Moses Itauma is on this card against little known Mike Balogun and it should be a big night for Itauma. The boys also preview the Kameda Promotions / ProBox TV main event Saturday in Osaka, JapanThis sees the return of American Angelo Leo against Tomoki Kameda, for Leo's IBF featherweight title in his first defense. Leo has big things in mind, but is going on the road in this one. Next, here briefly from former IBF 168 lb. champ Caleb Plant with DanPlant defends WBA interim super middleweight title vs. Armando Resendiz in the PBC on Prime Video main event May 31 at Mandalay Bay in Las Vegas News Pacquiao is officially back, and announces July 19th Mario Barrios fight on social media. His training has opened with Freddie Roach at Wild Card boxing club in L.A.Also, Dan is reporting that besides the bouts he's already reported that will be on the PPV (Fundora-Tszyu 2 and Pitbull-Fierro 2), the PPV will also include former 122 lb. and 126 lb. titlist  Brandon Figueroa vs. former title challenger Joey Gonzalez.Former IBF junior welterweight titlist Liam Paro will face Jonathan Navarro in a 10-rounder contracted at 144 pounds in the main event of a No Limit Boxing card on June 25 in Cairns, Australia. Paro's first fight since losing the IBF 140 title to Richardson Hitchins in December.And, we talk more about the death of all-time great Nino Benvenuti at 87 earlier this week.. The Italian legend was 1960 Olympic gold medalist, undisputed junior middleweight champion, two-time undisputed middleweight champion and was 2-1 in one boxing's most famed trilogies against Emile Griffith all for the undisputed 160 title. Some knowledge for the younger fans!Nostalgia May 22, 2010 – 15 years go on Thursday – the unfortunate fourth fight between featherweights Rafael Marquez and Israel Vazquez, who predictably got destroyed via KO3 in his final fight. and....May 22, 1993 – 32 years ago on Thursday – Roy Jones easy wiped out Bernard Hopkins in 12 rounds to win the vacant IBF middleweight title for his first world title in the co-feature of Riddick Bowe's easy KO2 in a mismatch with Jesse Ferguson to retain the heavyweight title. Goto our Big Fight Weekend Youtube paget to watch these here: https://www.youtube.com/@bigfightweekend9132/featuredAnd make sure to follow this podcast feed on Apple/Spreaker/Spotify, etc.! 

OpenAI's recent announcement that its nonprofit would “retain control” of its for-profit business sounds reassuring. But this seemingly major concession, celebrated by so many, is in itself largely meaningless.Litigator Tyler Whitmer is a coauthor of a newly published letter that describes this attempted sleight of hand and directs regulators on how to stop it.As Tyler explains, the plan both before and after this announcement has been to convert OpenAI into a Delaware public benefit corporation (PBC) — and this alone will dramatically weaken the nonprofit's ability to direct the business in pursuit of its charitable purpose: ensuring AGI is safe and “benefits all of humanity.”Right now, the nonprofit directly controls the business. But were OpenAI to become a PBC, the nonprofit, rather than having its “hand on the lever,” would merely contribute to the decision of who does.Why does this matter? Today, if OpenAI's commercial arm were about to release an unhinged AI model that might make money but be bad for humanity, the nonprofit could directly intervene to stop it. In the proposed new structure, it likely couldn't do much at all.But it's even worse than that: even if the nonprofit could select the PBC's directors, those directors would have fundamentally different legal obligations from those of the nonprofit. A PBC director must balance public benefit with the interests of profit-driven shareholders — by default, they cannot legally prioritise public interest over profits, even if they and the controlling shareholder that appointed them want to do so.As Tyler points out, there isn't a single reported case of a shareholder successfully suing to enforce a PBC's public benefit mission in the 10+ years since the Delaware PBC statute was enacted.This extra step from the nonprofit to the PBC would also mean that the attorneys general of California and Delaware — who today are empowered to ensure the nonprofit pursues its mission — would find themselves powerless to act. These are probably not side effects but rather a Trojan horse for-profit investors are trying to slip past regulators.Fortunately this can all be addressed — but it requires either the nonprofit board or the attorneys general of California and Delaware to promptly put their foot down and insist on watertight legal agreements that preserve OpenAI's current governance safeguards and enforcement mechanisms.As Tyler explains, the same arrangements that currently bind the OpenAI business have to be written into a new PBC's certificate of incorporation — something that won't happen by default and that powerful investors have every incentive to resist.Full transcript and links to learn more: https://80k.info/twChapters:Cold open (00:00:00)Who's Tyler Whitmer? (00:01:35)The new plan may be no improvement (00:02:04)The public hasn't even been allowed to know what they are owed (00:06:55)Issues beyond control (00:11:02)The new directors wouldn't have to pursue the current purpose (00:12:06)The nonprofit might not even retain voting control (00:16:58)The attorneys general could lose their enforcement oversight (00:22:11)By default things go badly (00:29:09)How to keep the mission in the restructure (00:32:25)What will become of OpenAI's Charter? (00:37:11)Ways to make things better, and not just avoid them getting worse (00:42:38)How the AGs can avoid being disempowered (00:48:35)Retaining the power to fire the CEO (00:54:49)Will the current board get a financial stake in OpenAI? (00:57:40)Could the AGs insist the current nonprofit agreement be made public? (00:59:15)How OpenAI is valued should be transparent and scrutinised (01:01:00)Investors aren't bad people, but they can't be trusted either (01:06:05)This episode was originally recorded on May 13, 2025.Video editing: Simon Monsour and Luke MonsourAudio engineering: Ben Cordell, Milo McGuire, Simon Monsour, and Dominic ArmstrongMusic: Ben CordellTranscriptions and web: Katy Moore