Podcasts about PBC

In the 3rd message of the Terms of Service series, Brother Luke looks at what it means to follow in the footsteps of Jesus. 02.08.26.Terms.of.Service.Part.3.Luke.Hagler

In a series I am calling the “Bible Profile” series, I look at the pre-flood patriarch Noah in this message. 02.11.26.Bible.Profile.of.Noah.Tim.McCool

A Tremendous performance by Ryan Garcia leads the weekend and we talk about his long awaited world title win on Saturday night in Vegas, plus the rest of the PPV card, a win for Leigh Wood in his all British showdown and some very intriguing fight news too on the "Fight Freaks Unite Recap Podcast!"Host T.J. Rives is back with insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter to go over it all.The start with the Ring mag DAZN PPV card Saturday night in Las Vegas ,as Ryan Garcia dominated Mario Barrios over 12 and wins the WBC welterweight crown. It was a great performance by "King Ry" and we dissect why.Next the Richardson Hitchins IBF 140 lb. defense with Oscar Duarte was canceled Saturday late morning in Vegas. Dan has the latest on what happened and why the conspiracy theorists should PIPE DOWN.Also, Gary Antuanne Russell W12 over Andy Hiraoka, and keeps the WBA junior welterweight crownFrank Martin had a draw with Nahir Albright in a junior welterweight clash.Bektemir Melikuziev deeats Sena Agbeko,and keeps WBA "Continental" super middleweight crownPlus Amari Jones and Mohammed Alakel get KOs, but American heayweight Joshua Edwards struggled over six rounds with his opponent, Brandon Colantonio.Next the Matchroom Boxing DAZN main event Saturday in Nottingham, EnglandLeigh Wood won an easy 12 rounder for the most part with Josh Warrington, in their junor lightweight rematch. Could it have been both of their final fights?Next, some NEWSHall of famer Floyd Mayweather, who turns 49 on Tuesday, announces he will exit retirement for an official fight later this summer after his spring exhibition with Mike Tyson slated for Afrrica.... WHAT ARE WE DOING HERE?!Next, in something of shocker, British welterweight star Conor Benn has signed with Zuffa Boxing, they announced on Friday. Per Dan's sources it is one-fight deal worth a staggering $15 million to fight by the end of May.  There are lots of takes, including T.J. pointing out that Zuffa is not raally revolutionizing anything... they're just like all the other promotions competing for fighters and willing to overpay to do it.And finally unified cruiserweight titleholder Gilberto “Zurdo” Ramirez and David Benavidez, the WBC light heavyweight titleholder moving up in weight, met he media on Saturday morning in Las Vegas to officially announce their May 2 PBC on Prime Video PPV fight, which will take place T-Mobile Arena.Dan has some thoughts on the kickoff presser.Hear it all on the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!

A Tremendous performance by Ryan Garcia leads the weekend and we talk about his long awaited world title win on Saturday night in Vegas, plus the rest of the PPV card, a win for Leigh Wood in his all British showdown and some very intriguing fight news too on the "Fight Freaks Unite Recap Podcast!"Host T.J. Rives is back with insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter to go over it all.The start with the Ring mag DAZN PPV card Saturday night in Las Vegas ,as Ryan Garcia dominated Mario Barrios over 12 and wins the WBC welterweight crown. It was a great performance by "King Ry" and we dissect why.Next the Richardson Hitchins IBF 140 lb. defense with Oscar Duarte was canceled Saturday late morning in Vegas. Dan has the latest on what happened and why the conspiracy theorists should PIPE DOWN.Also, Gary Antuanne Russell W12 over Andy Hiraoka, and keeps the WBA junior welterweight crownFrank Martin had a draw with Nahir Albright in a junior welterweight clash.Bektemir Melikuziev deeats Sena Agbeko,and keeps WBA "Continental" super middleweight crownPlus Amari Jones and Mohammed Alakel get KOs, but American heayweight Joshua Edwards struggled over six rounds with his opponent, Brandon Colantonio.Next the Matchroom Boxing DAZN main event Saturday in Nottingham, EnglandLeigh Wood won an easy 12 rounder for the most part with Josh Warrington, in their junor lightweight rematch. Could it have been both of their final fights?Next, some NEWSHall of famer Floyd Mayweather, who turns 49 on Tuesday, announces he will exit retirement for an official fight later this summer after his spring exhibition with Mike Tyson slated for Afrrica.... WHAT ARE WE DOING HERE?!Next, in something of shocker, British welterweight star Conor Benn has signed with Zuffa Boxing, they announced on Friday. Per Dan's sources it is one-fight deal worth a staggering $15 million to fight by the end of May.  There are lots of takes, including T.J. pointing out that Zuffa is not raally revolutionizing anything... they're just like all the other promotions competing for fighters and willing to overpay to do it.And finally unified cruiserweight titleholder Gilberto “Zurdo” Ramirez and David Benavidez, the WBC light heavyweight titleholder moving up in weight, met he media on Saturday morning in Las Vegas to officially announce their May 2 PBC on Prime Video PPV fight, which will take place T-Mobile Arena.Dan has some thoughts on the kickoff presser.Hear it all on the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

Talvipakkaset paukkaa, suksi vetää ja pulkka kulkee, mutta PBC on ja pysyy. Uuttakin uudemmassa jaksossa on taas luvassa varsin paljon kaikenmoista, kun yhtä jaksoa varten on kutsuttu paikalla joka kaksi erillistä tiimiä (Hazuki, Lionhead, Cerker sekä Norsukampa, Drifu, Qlaos) ja aiheet liitävät laidasta toiseen. Uutiskentällä leikitään jälleen pressicastiä, pääosiossa visaillaan Pokemon tietäjän arvonimestä Triple Threat -visailuformaatilla ja alkuosissa pääsevät pojat pois kahleistaan puhumaan viimeisistä vajaasta kolmen kuukauden aikaisista pelailuistaan. Cerker oli Sudaillut menemään Romeo is a Dead Mania, risteyttänyt Lionheadin kanssa kissoja Mewgenicsissä sekä hieman kiipeillyt Cairnin kanssa vuorilla. Lionhead vuorostaan ihmetteli Hazukin kanssa Quarantine Zone: The Last Check -pelin logiikkaa sekä oli pelaillut niin Outer Worlds kakkosta kuin myös High on Life kakkosta. Kaiken kukkuraksi Hazuki oli tutustunut Virtual Boyn NSO pelitarjontaan, kauhistellut Resident Evil 2 remaken tunnelmia sekä etsinyt Mauri Mursun kanssa pulloja. Tätä ja paljon muuta on jälleen tämäkin jakso täynnä. 01:52:43 Uutiset: State of Play 13.02.2026 02:56:10 Visailu: Pokémon Triple Threat 03:50:37 Edellinen kahden viikon kysymys: Kenen tunnetun suomalaishenkilön toivot löytyvän Epstein-tiedostoista? Musiikit: Dredge – The Restless Town Hello Kitty Island Adventure – Metal Ways for Stressful Days Clair Obscur: Expedition 33 – In Lumière’s Name Street Fighter 6 –  Alex’s Theme – Go! Alex! Hope is Born! by JAM Project Megabonk – Bonking in the forest Pokémon Heart Gold & Soul Silver – Route 47 Magical Tetris Challenge – Minnie’s Theme Front Mission 3 – Network Neon Genesis Evangelion (N64) – Komm, süsser Tod Kahden viikon kysymys: Kenestä olisi pitänyt tulla Suomen uusi sosiaali- ja ter­veys­mi­nis­te­ri?

One of the most endearing and important things we can do for one another, is to confess our faults to each other. Whether it is unintentional or something deliberate, an essential component in the experience of loving one another, is to have the Spiritual courage to confess. 02.08.26.Confessing.Our.Faults.Tim.McCool

Here is pt. 2 of the message, One Anothering No-no’s. 02.01.26.One.Anothering.No.Nos.pt.2.Tim.McCool

In the “one anothering” series I have been preaching, I come to some “no-no’s”. There are actions that are strictly forbidden towards one another. If we are to fulfill the law of Christ in the NT – to love one another – these are things we cannot engage in. Here is pt. 1 of this …

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

Corey Irbyfalse

Join the PBC family as we open God's Word together this morning.

Ulkona voi olla kylmä mutta PBC:tä kuunnellessa lämmin tunteiden vyöry valtaa kehon ja mielen. Kuumaa ja sensuellia puhetta irtoaa tällä kertaa mm. sellaisista peleistä kuin Darkenstein 3D, Fire Emblem Path of Radiance, Hollow Knight, Hitman (ne uudemman ajan), sekä ajankohtaisista aiheista joita tällä kertaa edustaa viimeisimmän Nintendo Directin läpikäynti. Pääosiossa kokeillaan jotain uutta, nimittäin tuttua ja turvallista top kolmosta, mutta tällä kertaa toivon mukaan vakioteemalla, eli valitun pelivuoden parhailla peleillä. Kuuntele jaksosta mitä sinun pitää tehdä jos haluat jatkossa lisää vastaavanlaisia top 3 -osioita. 01:10:58 Uutiset: Nintendo Direct: Partner Showcase – 05/02/2026 01:38:39 Top 3: Vuoden 1998 parhaat pelit 03:34:12 Edellinen kahden viikon kysymys: Mikä oli paras vuonna 1998 julkaistuista videopeleistä? Musiikit: Tomodachi Life – Map (Day) Tekken Tag Tournament – Character Select Goof Troop – Hamlet Pokémon Gold/Silver – Lance/Red TLoZ: Ocarina of Time – Kakariko Village Body Harvest – Indoor Music Dragon Quest VII Reimagined – Estard Banjo-Kazooie – Ending Kahden viikon kysymys: Kenen tunnetun suomalaishenkilön toivot löytyvän Epstein-tiedostoista?

Soul winning is a Biblical term. It is often heard in religious circles related to winning someone's soul eternally for Jesus (for example, accept Jesus, say the sinner’s prayer, be baptized, etc.). In this sermon, Brother Luke uses the account of Zacchaeus to show that the salvation in soul winning is not eternal, but a deliverance …

In this special edition episode of Liver Lineup, recorded as part of HCPLive's This Year in Medicine series, hosts Nancy Reau, MD, and Kimberly Brown, MD, break down the most consequential updates of the year across primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH), highlighting data that may reshape both near-term management and longer-term treatment strategies.Key episode timestamps:0:00:00 – Intro0:00:40 – Underuse of second‑line therapy in PBC0:03:40 – Long‑term data on PPAR agonists (elafibranor, seladelpar) in PBC0:09:35 – PSC: elafibranor (Elmwood trial) and CCL24 mAb (nabokitug)0:15:56 – Cholestasis symptoms: fatigue and pruritus and PPAR impact0:20:20 – Autoimmune hepatitis: limitations of current therapy; new agent 

Please see the following USPI, US ISI, EU SmPC and Canadian Product Monograph for complete LIVMARLI product information: US Important Safety Information (https://livmarli.com/important-safety-information/) US Prescribing Information (https://files.mirumpharma.com/livmarli/livmarli-prescribinginformation.pdf?_ga=2.264585739.54248471… EU SmPC (https://ec.europa.eu/health/documents/community-register/html/h1704.htm) Canadian Product Monograph (https://files.mirumpharma.com/livmarli/livmarli-product-monograph-en.pdf) Learn more about the latest research for Mirum’s investigational therapies: MRM-3379 (https://mirumpharma.com/wp-content/uploads/2025/09/FXS-NDD-2025-Mouse-Model-Poster_FINAL.pdf), volixibat in PSC (https://s29.q4cdn.com/633867992/files/doc_presentations/2024/Jun/Mirum-VISTAS-and-VANTAGE-Interim-Analysis-Results-Presentation.pdf) and PBC (https://mirumpharma.com/wp-content/uploads/2025/05/Heneghan-M-EASL-2025-VANTAGE-28-week-data-with-volixibat-in-PBC.pdf), and brelovitug (https://www.natap.org/2025/AASLD/AASLD_22.htm). LIVMARLI is also currently being evaluated in the Phase 3 EXPAND study (https://clinicaltrials.gov/study/NCT06553768) in additional settings of cholestatic pruritus. References What is hepatitis delta? Hepatitis B Foundation. Accessed January 14, 2026. https://www.hepb.org/research-and-programs/hepdeltaconnect/what-is-hepatitis-delta/ Agarwal K, Jucov A, Dobryanska M, et al. Brelovitug (BJT-778) monotherapy achieved 100% virologic response in patients with chronic hepatitis D: on treatment week 48 phase 2 study results. Presented at: AASLD 2025; November 7-11, 2025; Washington, D.C. Sagnelli C, Sagnelli E, Russo A, Pisaturo M, Occhiello L, Coppola N. HBV/HDV co-infection: epidemiological and clinical changes, recent knowledge and future challenges. Life (Basel). 2021;11(2):169. doi:10.3390/life11020169 Negro F, Lok AS. Hepatitis D: a review. JAMA. 2023;330(24):2376-2387. doi:10.1001/jama.2023.23242 Hunter J, Rivero-Arias O, Angelov A, Kim E, Fotheringham I, Leal J. Epidemiology of fragile X syndrome: A systematic review and meta‐analysis. doi:10.1002/ajmg.a.36511 See omnystudio.com/listener for privacy information.

New therapeutic agents for second-line treatment are raising the bar for primary biliary cholangitis (PBC) management. Listen now to learn how to incorporate these new agents into clinical practice and how these agents will impact attainment of treatment goals.Topics covered include:Available agents for second-line treatment of PBCAn overview of clinical trial data supporting second-line agents:Obeticholic acid (OCA)BezafibrateElafibranorSeladelparThis episode is the second of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/48MEc3rPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn how symptom management should be considered independently of PBC management, and how new therapeutic agents can help.Topics covered include:Mechanisms of pruritus and fatigue in PBCNonpharmacologic treatment optionsAn overview of clinical trial data supporting second-line agents for symptom management:BezafibrateElafibranorSeladelparInvestigational agents:VolixibatLinerixibatSetanaxibThis episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode:https://bit.ly/44ZJ5osPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Advancements in our understanding of primary biliary cholangitis (PBC) and new therapeutic agents have reshaped the care landscape of PBC. Listen now to learn how these developments are helping to redefine and elevate treatment goals. Topics covered include:How and when to assess treatment responseRisk factors in PBCBiochemical treatment response and fibrosis stage as predictors of transplant-free survivalDynamics of liver stiffness measurements and clinical outcomes in PBCThe importance of bilirubin and alkaline phosphatase normalizationThis episode is the first of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/44ZJ5osPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify.   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Liver Lineup: Updates & Unfiltered Insights, host Nancy Reau, MD, sits down with Kris Kowdley, MD, to discuss evolving approaches in cholestatic liver disease, with a particular focus on primary biliary cholangitis (PBC).Key episode timestamps:0:00:00 – Guest intro & evolution of PBC therapy0:07:34 – Redefining biochemical response & earlier assessment0:16:26 – OCA withdrawal & positioning PPARs/fibrates0:22:16 – Diagnosing AMA‑negative PBC0:25:58 – Genetic cholestasis panels & PFIC spectrum0:29:45 – Symptom burden, pruritus, & IBAT inhibitors0:35:17 – Bone health & closing remarks

Tune in to listen as expert faculty, Dr Christopher L. Bowlus and Dr Sonal Kumar, discuss recent developments in treating primary biliary cholangitis (PBC) with new and emerging agents, as well as strategies to integrate these advances into clinical practice.Topics covered include: Methods of Assessing PBC Disease ProgressionNewer Agents for Second-line Treatment of PBCPrioritizing Symptom Management and Quality of Life With PBC TreatmentPresenters:Christopher L. Bowlus, MDLena Valenta Professor and ChiefDivision of Gastroenterology and HepatologySchool of Medicine University of California Davis Sacramento, CaliforniaSonal Kumar, MD, MPHAssistant Professor of MedicineDivision of Gastroenterology and HepatologyWeill Cornell Medical CollegeNew York, New YorkLink to full program: https://bit.ly/43nHx6UGet access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Listen in as Nancy Reau, MD, reviews key highlights of the most impactful primary biliary cholangitis (PBC) research and gain insights on how to apply these new advances to clinical practice. Topics covered include:Treatment GoalsLong-term Data With PPAR AgonistsInvestigational Therapies for PruritusPresenter: Nancy Reau, MDProfessor of MedicineRichard B. Capps Chair of HepatologyChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRush University Medical CenterChicago, IllinoisTo download the accompanying slides, visit the program page for this episode: https://bit.ly/4b2d6YD Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Recent advances in primary biliary cholangitis (PBC) care have resulted in a new focus on personalized care and symptom management. Tune in to learn from patient advocate, Maria G. Morais, RN, how you can integrate patient insights and priorities into treatment plans for PBC. Topics covered include:The Canadian PBC Society Survey: Comorbidities and Treatment GoalsDefining and Achieving Goal-Driven Care for PBCRecent Advances in PBC ManagementNewer Agents for Second-line Treatment of PBCPresenters:Maria G. Morais, RNPBC Transplant PatientVP Patient AdvocacyCanadian PBC SocietyToronto, CanadaLink to full program:https://bit.ly/44ySoL3Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

In Galatians 6, we are told to bear one another’s burdens, and then, that we should bear our own burden. If we ever think there is a contradiction in the scripture, it can only be in our own minds. If we look closely at what Paul is teaching, we see glorious instruction on how we …

In the Terms of Service series, Brother Luke looks at the Lord’s instruction to follow him. When we think of following, we often think in terms of following directions. We follow directions to arrive at an accomplished end or desired outcome, whether it’s cooking, driving, or assembling something. When we reach the end of our …

Ryan Adamsfalse

As I continue preaching on the “one anothers” of the NT, in this message I look at how we are to be likeminded towards one another, and to receive one another, and admonish one another. 01.18.26.Likeminded.Tim.McCool

Join the PBC family as we open God's Word together this morning.

Ursodiol (ursodeoxycholic acid) is a prescription bile acid medication used to dissolve cholesterol gallstones, prevent gallstones during rapid weight loss, and treat liver diseases like primary biliary cholangitis (PBC) by reducing toxic bile acids and cholesterol production. It works by changing bile composition, making it less saturated with cholesterol, and is available as oral medication. Of course, it is also the foundational medication for treatment of diagnosed Intrahepatic Cholestasis of Pregnancy (ICP). Does this medication reduce adverse perinatal outcomes? In this episode, we will review a new study from the Green Journal, which will be out in February 2026, examining the recurrence risk for ICP using data from NY. In a patient with prior history of ICP, is there any guidance on monitoring of serum bile acids in the subsequent pregnancy before symptoms develop? We will explain. PLUS we will review the data on whether Ursodiol may hold promise in recurrence prevention or in reduction of adverse outcomes once the condition is diagnosed. Listen in for details. 1. 2019: Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, Chambers J, Hunter R, Dorling J, Williamson C, Thornton JG; PITCHES study group. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet. 2019 Sep 7;394(10201):849-860. doi: 10.1016/S0140-6736(19)31270-X. Epub 2019 Aug 1. PMID: 31378395; PMCID: PMC6739598. https://pubmed.ncbi.nlm.nih.gov/31378395/2. February 08, 2025: Rahim, Mussarat N et al. Pregnancy and the liver. The Lancet. 2021; Volume 405, Issue 10477, 498 – 513 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02351-1/fulltext3. SMFM CS 53; 20214. Rosenberg, Henri M. MD; Sarker, Minhazur R. MD; Ramos, Gladys A. MD; Bianco, Angela MD; Ferrara, Lauren MD; DeBolt, Chelsea A. MD. Intrahepatic Cholestasis of Pregnancy Recurrence in a Subsequent Pregnancy. Obstetrics & Gynecology 147(2):p 239-241, February 2026. | DOI: 10.1097/AOG.0000000000006033 https://journals.lww.com/greenjournal/fulltext/2026/02000/intrahepatic_cholestasis_of_pregnancy_recurrence.13.aspx5. Ovadia C, Sajous J, Seed PT et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2021 Jul;6(7):547-558. doi: 10.1016/S2468-1253(21)00074-1. Epub 2021 Apr 27. PMID: 33915090; PMCID: PMC8192305.6. EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy. European Association for the Study of the Liver; 2023

On our Wednesday night service, I have begun a series that looks at certain Biblical characters. The first two characters are Adam and Eve. 01.14.26.Adam.and.Eve.Tim.McCool

Continuing in the “One Anothering” series, I come to the very specific instruction on how to love one another in Christian liberty. 01.11.26.Christian.Liberty.Tim.McCool

Ryan Adamsfalse

Matt and EzRaw discuss the latest in boxing news, including:News and Notes- Oscar De La Hoya throws down the gauntlet to Jaron Ennis and Eddie Hearn. Says Vergil Ortiz vs. Boots will have to be a 60-40 split in favor of Ortiz. Fair or foul?- Ryan García vs. Mario Barrios details to be announced on Monday. Buzz check?- Robert García says that Bam Rodriguez will fight the winner of Naoya Inoue-Junto Nakatani. What are the odds Bam actually makes the jump?- Dmitry Bivol is aiming for a spring return to the ring against Michael Eifert, according to his manager. How should boxing fans feel about this development?- Fabio Wardley targeting Tyson Fury in 2026. Is this a good fight for Fury?- Jaime Munguia joins Canelo Alvarez in turning down the IBF Super Middleweight title shot against Osleys Iglesias. Thoughts? Does anyone want smoke with the Tornado?- Zuffa Boxing officially announced Callum Walsh vs. Carlos Ocampo, as first reported by Brunch Boxing. How are we feeling about the Zuffa kickoff?- Frank Martin is pushing for a fight with IBF champion Richardson Hitchins. PBC willing to make the fight. What are the odds Hitchins takes the fight?- Curmel Moton set to return on February 28 at a Manny Pacquiao Promotions show. Thoughts on where Moton is at in his career?- Subriel Matias had his gloves rejected by the NY Athletic Commission, following a complaint from Dalton Smith's team, Rob Tebbutt reports. Will this have any effect on the fight?EZ Money Parlay of the Day, EzRaw Report Card, EzRaw Breakdown - EzRaw Report Card and EzRaw Breakdown: Subriel Matias vs. Dalton Smith, Agit Kabayel vs. Damian Knyba- Mike's Ez Money Parlay, Ezra's Raw Hard Cash and Matt's Best Bet. Booking the Territory: Boxing Draft Recap, Picks for January-February- The guys held their 3rd annual boxing draft. Who won?- The guys make their picks on this week's bouts, and more. How did they do so far?Quick Hits- The IBF to order welterweight champion Lewis Crocker to face mandatory challenger Liam Paro, Tokkers reports. Thoughts on this decision?- The IBF has granted an extension for the Frank Sanchez-Richard Torrez IBF title eliminator, as both sides work towards a deal. Who wins this potential bout?- Albert Ramirez defends his interim WBA Lightweight Heavyweight Championship against Lerrone Richards on February 5. How are we feeling about Ramirez?- Brandon Adams-Caoimhin Agyarko reach deal for IBF title eliminator in April.

In the ongoing series on the terms of discipleship, Brother Luke looks at Jesus’ commandment to follow Him. We can follow people and things for many different reasons and in many ways. In this sermon Brother Luke compares the way we ‘follow’ people on social media platforms because of our interest in what they are doing to following …

This week on the Team Lally Real Estate Radio Show, we interview Mark Faildo of Premier Benefit Consultants. He demystifies Medicare—what it covers, when to plan, how income affects premiums, and why many Hawaii residents qualify for affordable, even zero-premium plans. Mark also shares critical planning tips for those approaching age 65, military retirees, and anyone looking to avoid costly lifelong penalties by getting Medicare right the first time.We also have our Experts We Trust. Danny Langerman of DHA Financial explains why today's market conditions still favor buyers, why VA loans remain one of the best financing options available, and how to think strategically about refinancing. Renee Ube of Your VA Match joins the conversation to share how delegating the right tasks to virtual assistants can unlock growth, scale your business, and multiply your time when done with clarity and feedback.Who is Mark Faildo?Mark Faildo is a dedicated Medicare expert with deep roots in Hawaii, having grown up in Kalihi and earned his diploma from Farrington High School. Before moving into the world of Medicare education and planning, Mark built a successful career in the hospitality industry, managing food and beverage operations at renowned local hotels including Hilton Hawaiian Village, Sheraton Waikiki, and the Prince Kuhio Hotel, and later advancing into leadership as a District Manager with Starbucks. He also served his country with honor, retiring after 22 years with the Army National Guard and Army Reserve, an experience that shaped his service-first mindset. After navigating the confusing landscape of Medicare while helping his own parents, Mark committed himself to mastering the system; sixteen years later, he now guides individuals and families through Medicare with compassion, integrity, and clarity, helping them make confident, informed decisions about their options as a licensed agent with Premier Benefit Consultants.PbchawaiiPremier Benefit Consultants (PBC) is a well-established, independent Medicare insurance agency that specializes in helping people understand and navigate the often complex world of Medicare — absolutely free of charge. With over 100 local agents across the Hawaiian Islands, PBC offers personalized consultations, Medicare group education, and company Medicare planning to individuals, families, employers, and community groups, treating clients like family and making sure they have the right coverage for their unique needs. They represent every Medicare Advantage plan available in Hawaii, allowing them to provide unbiased advice and tailor solutions based on what's truly best for each client. Committed to service, integrity, and education since 2008, PBC prides itself on phenomenal customer care, ongoing support during and after enrollment, and accessible communication with agents speaking many languages to serve Hawaii's diverse communities.To reach Mark Faildo, you may contact him in the following ways:Phone: 808-292-7092Email: Mark@pbchawaii.comWebsite: https://www.pbchawaii.com/

Ryan Adamsfalse

In the first message of the new year, I look at the lessons of Psalm 40. Waiting and listening to the Lord is a skill to develop. It is even harder to develop in our culture because of earbuds, music and noise blaring in restaurants and gas stations. Getting in a quiet place to wait …

In the “one another” series, I look at specific ways that the NT gives us to love one another, as Jesus instructed. 12.28.25.One.Anothering.Each.Other.Tim.McCool

In the 2nd sermon on the terms of discipleship, Brother Luke looks at Jesus’ instruction that we are to take up our cross. The cross that Jesus carried was a symbol of many things, including being a picture of the burdens that evil men place on us for being servants of the Most High God. …

In Matthew 16, we read of Jesus Christ preaching about what is expected of his disciples. In the same way an athlete or solider may be told what is expected of them as being a part of a team or army, Jesus gives clear instruction on the terms of service for his disciples. In this …

As I continue in the “one anothering” series, in this message I look at the characteristics of agape love. 12.10.25.Characteristics.of.Agape.Love.Tim.McCool

Ryan Adamsfalse

Ryan Adamsfalse

Listen in as Nancy Reau, MD, reviews key highlights of the most impactful primary biliary cholangitis (PBC) research and gain insights on how to apply these new advances to clinical practice. Topics covered include:Treatment GoalsLong-term Data With PPAR AgonistsInvestigational Therapies for PruritusPresenter: Nancy Reau, MDProfessor of MedicineRichard B. Capps Chair of HepatologyChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRush University Medical CenterChicago, IllinoisTo download the accompanying slides, visit the program page for this episode: https://bit.ly/4b2d6YD  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

 Unlock the secrets behind peak physique and next-level coaching in this “Peak Physique Podcast.” Join host Andre Adams, NASM Master Trainer and IFBB Physique Olympian, alongside featured guest, Dr. Guillermo Escalante, the lead SME behind the new NASM Physique and Bodybuilding Coach (PBC) course. Curious about what sets the PBC apart? Get insider insights on the making of this revolutionary certification, the high-profile NASM partnership with the NPC and IFBB Pro League, and a behind-the-scenes look at the industry's most respected experts shaping the curriculum—think Brad Schoenfeld, Eric Helms, Scott Stevenson, and more. But that's just the start! Andre and Dr. G. break down advanced hypertrophy training strategies—supersets, drop sets, rest-pause sets, and giant sets—including practical applications to break your muscle-building plateaus. Plus, hear the latest science on muscle protein synthesis and segmental hypertrophy for real-world physique sculpting. The encore presentation goes deep on a hot, often misunderstood topic: the prevalence and cardiovascular risks of anabolic androgenic steroids (AAS) for both bodybuilders and everyday gym-goers. Learn why honest healthcare communication is critical, discover which biomarkers to watch, and get actionable advice on safe, effective evidence-based coaching. Whether you're prepping for the stage, growing your client base, or hungry for muscle science, this episode delivers expert-tested tactics and thought-provoking discussion you won't find anywhere else. Tune in and level up your knowledge—your results (and heart health) will thank you! If you like what you just consumed, leave us a 5-star review, and share this episode with a friend to help grow our NASM health and wellness community! The content shared in this podcast is solely for educational and entertainment purposes. It is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek out the guidance of your healthcare provider or other qualified professional. Any opinions expressed by guests and hosts are their own and do not necessarily reflect the views of NASM. Introducing NASM One, the membership for trainers and coaches. For just $35/mo, get unlimited access to over 300 continuing education courses, 50% off additional certifications and specializations, EDGE Trainer Pro all-in-one coaching app to grow your business, unlimited exam attempts and select waived fees. Stay on top of your game and ahead of the curve as a fitness professional with NASM One. Click here to learn more. https://bit.ly/3zoMWyV

Jesus gave a new commandment for disciples in the New Testament – to love one another. In this message, I introduce the “one anotherings” in the New Testament age, observing what a unique and dynamic shift this was for worshippers of God. 12.07.25.One.Anotherings.Tim.McCool