Podcasts about PBC

Off of a controversial wekend in Vegas, where it ended up that Jai Opetaia of Australia was NOT the IBF champiion any longer for fighting the Zuffa Boxing main event, we're ready to recap his victory in the ring, have some other fight news and more on the 'Fight Freaks Unite Recap" Podcast!Host T.J. Rives and insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter have their insight on it all.They begin with the background of the IBF stripping Opetaia just before the bout in Las Vegas with American Brandon Glanton- a fight that the Aussie won easily over 12 rounds. It was still for the Ring Magazine version of the crusierweight crown and  for Opetaia's lineal cruiserweight title, but Dan wants to konw- WHAT ARE WE DOING HERE?!The guys have thoughts, including the ramifications for Opetaia down the road, etc.Also, there's a recap of former WBA featherweight titlist Mauricio Lara scoring a TKO2 over Mexican countryman Rafael Rosas on Saturday night in the main event of the Boxstrs/Chiquita Boxing card that headlined the ESPN "Knock Out" telecast.  Then, some news:WBO welterweight titleholder Devin Haney and WBA titlist Rolando Romero are negotiating a unification fight targeted for May 30 at Barclays Center in Brooklyn, New York. The bout would be PBC on Prime Video PPV and Dan has also latest.Next, undisputed junior featherweight champion Naoya Inoue will defend his crown against three-division titleholder Junto Nakatani in the long-expected and highly anticipated showdown on May 2nd at the Tokyodome in Tokyo, Ohashi Promotions announced at a news conference on Friday in Tokyo. This is a tremendous all Japanese matchup that we are looking forward to for May.We have more on Friday's announcement of the Most Valuable Promotions/ESPN deal that is long term for women's boxing to regularly be part of ESPN's linear channel and their other platforms over a multi-year deal. Alycia Baumgardner headlines the first U.S. show in April.The WBC has ordered junior welterweight titlist Dalton Smith to make his first defense against mandatory challenger and former titleholder Alberto Puello. A purse bid on April 3rd will happen, if no deal is reached before then.And, Mario Barrios announced that he will move up to junior middleweight in the wake of losing the WBC welterweight title by near-shutout decision to Ryan Garcia last month.It's all part of the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.! 

Off of a controversial wekend in Vegas, where it ended up that Jai Opetaia of Australia was NOT the IBF champiion any longer for fighting the Zuffa Boxing main event, we're ready to recap his victory in the ring, have some other fight news and more on the 'Fight Freaks Unite Recap" Podcast!Host T.J. Rives and insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter have their insight on it all.They begin with the background of the IBF stripping Opetaia just before the bout in Las Vegas with American Brandon Glanton- a fight that the Aussie won easily over 12 rounds. It was still for the Ring Magazine version of the crusierweight crown and  for Opetaia's lineal cruiserweight title, but Dan wants to konw- WHAT ARE WE DOING HERE?!The guys have thoughts, including the ramifications for Opetaia down the road, etc.Also, there's a recap of former WBA featherweight titlist Mauricio Lara scoring a TKO2 over Mexican countryman Rafael Rosas on Saturday night in the main event of the Boxstrs/Chiquita Boxing card that headlined the ESPN "Knock Out" telecast.  Then, some news:WBO welterweight titleholder Devin Haney and WBA titlist Rolando Romero are negotiating a unification fight targeted for May 30 at Barclays Center in Brooklyn, New York. The bout would be PBC on Prime Video PPV and Dan has also latest.Next, undisputed junior featherweight champion Naoya Inoue will defend his crown against three-division titleholder Junto Nakatani in the long-expected and highly anticipated showdown on May 2nd at the Tokyodome in Tokyo, Ohashi Promotions announced at a news conference on Friday in Tokyo. This is a tremendous all Japanese matchup that we are looking forward to for May.We have more on Friday's announcement of the Most Valuable Promotions/ESPN deal that is long term for women's boxing to regularly be part of ESPN's linear channel and their other platforms over a multi-year deal. Alycia Baumgardner headlines the first U.S. show in April.The WBC has ordered junior welterweight titlist Dalton Smith to make his first defense against mandatory challenger and former titleholder Alberto Puello. A purse bid on April 3rd will happen, if no deal is reached before then.And, Mario Barrios announced that he will move up to junior middleweight in the wake of losing the WBC welterweight title by near-shutout decision to Ryan Garcia last month.It's all part of the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.! 

Kevättä rinnassa ja PBC:tä korvissa. Ei ole ihmisen elämässä mitään parempaa, paitsi ehkä 4772095 jotain muuta asiaa mutta kuitenkin. Tässä uusimmassa taideteoksessa pääsette kuulemaan analyyttista keskustelua mm. lukuisista Steam-demoista, Mario Tennis Feveristä, Pokémon FireRedistä, Fletcher's Questistä, Xbox-pomojen alasajosta, Pokémon-Directin sisällöstä ja monesta muusta aurinkoisesta 01:04:54 Uutiset: Pokémon täytti pyöreitä ja paljasteli asioita R.I.P. eli Rest In Phil Lause ei enää pääty siniseen pisteeseen 01:47:35 Top 3: Resident Evil -pelit 03:03:14 Edellinen kahden viikon kysymys: Kenestä olisi pitänyt tulla Suomen uusi sosiaali- ja ter­veys­mi­nis­te­ri? Musiikit: Lion King (SNES) – Credits Pokémon FR/LG – Lavender Town Donkey Kong Bananza – Lagoon Layer Resident Evil: Deadly Silence – Save Room Resident Evil Remake – Save Room Resident Evil Gaiden – Battle Theme Backyard Baseball 97 – Main Menu Goonies II – Ending Kahden viikon kysymys: Mikä on huonoin KAIKISTA Resident Evil -peleistä?

Content warning: sexual abuse, sexual assault, childhood sexual abuse, statutory rape, human trafficking, sex trafficking, and suicide.This episode originally aired on November 29th, 2024.Lisa Phillips is a model, actress, survivor, and victim advocate who has spent much of her life all over the world. While cultivating a career in the modeling and acting industries, Lisa even found herself overseas and as a guest on Jeffrey Epstein's private island. That specific trip would become quite traumatic for Lisa, and although she would never return to the property again, she would soon be trafficked into a vast and widespread ring that enabled mass sexual assault. However, it wouldn't be until after navigating the legal system and sharing her story with other survivors of the same serial abuser, that Lisa truly was confronted by the depth of her trauma. The Broken Cycle Media team is so grateful Lisa was willing to share all that came next for her in her healing process, and in creating her beautiful podcast community entitled From Now On.Lisa's Links:From Now On Podcast: https://www.lisaphillips.la/podcastLisa Phillips' Website: https://www.lisaphillips.la/From Now On Podcast Instagram: http://www.instagram.com/fromnowonpodLisa's Instagram: http://www.instagram.com/iamlisaphillipsFor more resources and a list of related non-profit organizations, please visit http://www.somethingwaswrong.com/resourcesSources:ABC 7 Chicago. (2024, July 2). Jeffrey Epstein grand jury documents released by judge in Florida [Video]. YouTube. https://www.youtube.com/watch?v=8x8ESdS_mkU.CBS New York. (2019, July 6). Jeffrey Epstein Arrested For Sex Trafficking [Video]. YouTube. https://www.youtube.com/watch?v=0tJ9-tFKJaA&list=PPSVCohen, L. (2023, November 9). JPMorgan's $290 million settlement with Epstein accusers approved by US judge. Reuters. https://www.reuters.com/legal/us-judge-weigh-jpmorgans-290-million-settlement-with-epstein-accusers-2023-11-09/Ghislaine Maxwell Charged In Manhattan Federal Court For Conspiring With Jeffrey Epstein To Sexually Abuse Minors. (2020, July 2). United States Attorney's Office. https://www.justice.gov/usao-sdny/pr/ghislaine-maxwell-charged-manhattan-federal-court-conspiring-jeffrey-epstein-sexuallyGhislaine Maxwell Sentenced To 20 Years In Prison For Conspiring With Jeffrey Epstein To Sexually Abuse Minors. (2022, June 28). United States Attorney's Office. https://www.justice.gov/usao-sdny/pr/ghislaine-maxwell-sentenced-20-years-prison-conspiring-jeffrey-epstein-sexually-abuseNBC News. (2024, January 4). Newly unsealed documents reveal Jeffrey Epstein's relationships with powerful people [Video]. YouTube. https://www.youtube.com/watch?v=4_x7tg5YO5s&t=4sJeffrey Epstein Charged In Manhattan Federal Court With Sex Trafficking Of Minors. (2019, July 8). Press Release. https://www.justice.gov/usao-sdny/pr/jeffrey-epstein-charged-manhattan-federal-court-sex-trafficking-minorsJudge releases 2006 PBC grand jury documents in Jeffrey Epstein criminal case. (2024, July 1). [Video]. YouTube. https://www.youtube.com/watch?v=JfPV4c2Tnic&t=32sOver $150 Million Paid to Jeffrey Epstein Victims by His Estate Claim Executors in Latest Financial Filing. (2023, November 14). Inside Edition. https://www.insideedition.com/jeffrey-epstein-victims-payments-estate-valueWill We Ever Know How Many Girls Jeffrey Epstein Abused? (2019, July 19). The Cut. https://www.thecut.com/2019/07/how-many-jeffrey-epstein-victims-are-there.htmlWFLA News Channel 8. (2024, July 2). New documents reveal sordid life of Billionaire Jeffrey Epstein [Video]. YouTube. https://www.youtube.com/watch?v=HloA3-rZnFw&list=PPSV&t=72sWPBF 25 News. (2024, July 1). Judge releases grand jury records in 2008 Jeffrey Epstein criminal case [Video]. YouTube. https://www.youtube.com/watch?v=t3erEsEhjLk&t=12sWPTV News. (2024, July 1). Breakdown of newly released Epstein grand jury testimony [Video]. YouTube. https://www.youtube.com/watch?v=rCz87fmI5ks&list=PPSVThank you again to Quince for sponsoring this episode. Don't forget to go to Quince.com/WCN for free shipping and 365-day returns. That's a full year to wear it and love it. And you will. Now available in Canada, too.

I have been asked recently about the “big 4” questions in life. Those questions are, in general, 1. where to live, 2. where to work, 3. where to worship, and 4. who to marry? If we get one or more of these wrong, it spells disaster for a child of God. In this first message, …

In the final message on the terms of service of a disciple of Christ, Brother Luke looks at how faithfully being a disciple of Christ results in truly finding your life. When the most solid disciples of the Bible faced persecution and trouble, their peace of mind never left, truly showing that when we follow Jesus …

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

In the 3rd message of the Terms of Service series, Brother Luke looks at what it means to follow in the footsteps of Jesus. 02.08.26.Terms.of.Service.Part.3.Luke.Hagler

In a series I am calling the “Bible Profile” series, I look at the pre-flood patriarch Noah in this message. 02.11.26.Bible.Profile.of.Noah.Tim.McCool

A Tremendous performance by Ryan Garcia leads the weekend and we talk about his long awaited world title win on Saturday night in Vegas, plus the rest of the PPV card, a win for Leigh Wood in his all British showdown and some very intriguing fight news too on the "Fight Freaks Unite Recap Podcast!"Host T.J. Rives is back with insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter to go over it all.The start with the Ring mag DAZN PPV card Saturday night in Las Vegas ,as Ryan Garcia dominated Mario Barrios over 12 and wins the WBC welterweight crown. It was a great performance by "King Ry" and we dissect why.Next the Richardson Hitchins IBF 140 lb. defense with Oscar Duarte was canceled Saturday late morning in Vegas. Dan has the latest on what happened and why the conspiracy theorists should PIPE DOWN.Also, Gary Antuanne Russell W12 over Andy Hiraoka, and keeps the WBA junior welterweight crownFrank Martin had a draw with Nahir Albright in a junior welterweight clash.Bektemir Melikuziev deeats Sena Agbeko,and keeps WBA "Continental" super middleweight crownPlus Amari Jones and Mohammed Alakel get KOs, but American heayweight Joshua Edwards struggled over six rounds with his opponent, Brandon Colantonio.Next the Matchroom Boxing DAZN main event Saturday in Nottingham, EnglandLeigh Wood won an easy 12 rounder for the most part with Josh Warrington, in their junor lightweight rematch. Could it have been both of their final fights?Next, some NEWSHall of famer Floyd Mayweather, who turns 49 on Tuesday, announces he will exit retirement for an official fight later this summer after his spring exhibition with Mike Tyson slated for Afrrica.... WHAT ARE WE DOING HERE?!Next, in something of shocker, British welterweight star Conor Benn has signed with Zuffa Boxing, they announced on Friday. Per Dan's sources it is one-fight deal worth a staggering $15 million to fight by the end of May.  There are lots of takes, including T.J. pointing out that Zuffa is not raally revolutionizing anything... they're just like all the other promotions competing for fighters and willing to overpay to do it.And finally unified cruiserweight titleholder Gilberto “Zurdo” Ramirez and David Benavidez, the WBC light heavyweight titleholder moving up in weight, met he media on Saturday morning in Las Vegas to officially announce their May 2 PBC on Prime Video PPV fight, which will take place T-Mobile Arena.Dan has some thoughts on the kickoff presser.Hear it all on the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!

A Tremendous performance by Ryan Garcia leads the weekend and we talk about his long awaited world title win on Saturday night in Vegas, plus the rest of the PPV card, a win for Leigh Wood in his all British showdown and some very intriguing fight news too on the "Fight Freaks Unite Recap Podcast!"Host T.J. Rives is back with insider Dan Rafael of his Fight Freaks Unite Substack and Newsletter to go over it all.The start with the Ring mag DAZN PPV card Saturday night in Las Vegas ,as Ryan Garcia dominated Mario Barrios over 12 and wins the WBC welterweight crown. It was a great performance by "King Ry" and we dissect why.Next the Richardson Hitchins IBF 140 lb. defense with Oscar Duarte was canceled Saturday late morning in Vegas. Dan has the latest on what happened and why the conspiracy theorists should PIPE DOWN.Also, Gary Antuanne Russell W12 over Andy Hiraoka, and keeps the WBA junior welterweight crownFrank Martin had a draw with Nahir Albright in a junior welterweight clash.Bektemir Melikuziev deeats Sena Agbeko,and keeps WBA "Continental" super middleweight crownPlus Amari Jones and Mohammed Alakel get KOs, but American heayweight Joshua Edwards struggled over six rounds with his opponent, Brandon Colantonio.Next the Matchroom Boxing DAZN main event Saturday in Nottingham, EnglandLeigh Wood won an easy 12 rounder for the most part with Josh Warrington, in their junor lightweight rematch. Could it have been both of their final fights?Next, some NEWSHall of famer Floyd Mayweather, who turns 49 on Tuesday, announces he will exit retirement for an official fight later this summer after his spring exhibition with Mike Tyson slated for Afrrica.... WHAT ARE WE DOING HERE?!Next, in something of shocker, British welterweight star Conor Benn has signed with Zuffa Boxing, they announced on Friday. Per Dan's sources it is one-fight deal worth a staggering $15 million to fight by the end of May.  There are lots of takes, including T.J. pointing out that Zuffa is not raally revolutionizing anything... they're just like all the other promotions competing for fighters and willing to overpay to do it.And finally unified cruiserweight titleholder Gilberto “Zurdo” Ramirez and David Benavidez, the WBC light heavyweight titleholder moving up in weight, met he media on Saturday morning in Las Vegas to officially announce their May 2 PBC on Prime Video PPV fight, which will take place T-Mobile Arena.Dan has some thoughts on the kickoff presser.Hear it all on the "Fight Freaks Unite Recap Podcast" and make sure to follow/subscribe on Apple/Spreaker/Spotify, etc.!

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

Talvipakkaset paukkaa, suksi vetää ja pulkka kulkee, mutta PBC on ja pysyy. Uuttakin uudemmassa jaksossa on taas luvassa varsin paljon kaikenmoista, kun yhtä jaksoa varten on kutsuttu paikalla joka kaksi erillistä tiimiä (Hazuki, Lionhead, Cerker sekä Norsukampa, Drifu, Qlaos) ja aiheet liitävät laidasta toiseen. Uutiskentällä leikitään jälleen pressicastiä, pääosiossa visaillaan Pokemon tietäjän arvonimestä Triple Threat -visailuformaatilla ja alkuosissa pääsevät pojat pois kahleistaan puhumaan viimeisistä vajaasta kolmen kuukauden aikaisista pelailuistaan. Cerker oli Sudaillut menemään Romeo is a Dead Mania, risteyttänyt Lionheadin kanssa kissoja Mewgenicsissä sekä hieman kiipeillyt Cairnin kanssa vuorilla. Lionhead vuorostaan ihmetteli Hazukin kanssa Quarantine Zone: The Last Check -pelin logiikkaa sekä oli pelaillut niin Outer Worlds kakkosta kuin myös High on Life kakkosta. Kaiken kukkuraksi Hazuki oli tutustunut Virtual Boyn NSO pelitarjontaan, kauhistellut Resident Evil 2 remaken tunnelmia sekä etsinyt Mauri Mursun kanssa pulloja. Tätä ja paljon muuta on jälleen tämäkin jakso täynnä. 01:52:43 Uutiset: State of Play 13.02.2026 02:56:10 Visailu: Pokémon Triple Threat 03:50:37 Edellinen kahden viikon kysymys: Kenen tunnetun suomalaishenkilön toivot löytyvän Epstein-tiedostoista? Musiikit: Dredge – The Restless Town Hello Kitty Island Adventure – Metal Ways for Stressful Days Clair Obscur: Expedition 33 – In Lumière’s Name Street Fighter 6 –  Alex’s Theme – Go! Alex! Hope is Born! by JAM Project Megabonk – Bonking in the forest Pokémon Heart Gold & Soul Silver – Route 47 Magical Tetris Challenge – Minnie’s Theme Front Mission 3 – Network Neon Genesis Evangelion (N64) – Komm, süsser Tod Kahden viikon kysymys: Kenestä olisi pitänyt tulla Suomen uusi sosiaali- ja ter­veys­mi­nis­te­ri?

One of the most endearing and important things we can do for one another, is to confess our faults to each other. Whether it is unintentional or something deliberate, an essential component in the experience of loving one another, is to have the Spiritual courage to confess. 02.08.26.Confessing.Our.Faults.Tim.McCool

In the “one anothering” series I have been preaching, I come to some “no-no’s”. There are actions that are strictly forbidden towards one another. If we are to fulfill the law of Christ in the NT – to love one another – these are things we cannot engage in. Here is pt. 1 of this …

Here is pt. 2 of the message, One Anothering No-no’s. 02.01.26.One.Anothering.No.Nos.pt.2.Tim.McCool

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

Join the PBC family as we open God's Word together this morning.

Corey Irbyfalse

Soul winning is a Biblical term. It is often heard in religious circles related to winning someone's soul eternally for Jesus (for example, accept Jesus, say the sinner’s prayer, be baptized, etc.). In this sermon, Brother Luke uses the account of Zacchaeus to show that the salvation in soul winning is not eternal, but a deliverance …

In this special edition episode of Liver Lineup, recorded as part of HCPLive's This Year in Medicine series, hosts Nancy Reau, MD, and Kimberly Brown, MD, break down the most consequential updates of the year across primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH), highlighting data that may reshape both near-term management and longer-term treatment strategies.Key episode timestamps:0:00:00 – Intro0:00:40 – Underuse of second‑line therapy in PBC0:03:40 – Long‑term data on PPAR agonists (elafibranor, seladelpar) in PBC0:09:35 – PSC: elafibranor (Elmwood trial) and CCL24 mAb (nabokitug)0:15:56 – Cholestasis symptoms: fatigue and pruritus and PPAR impact0:20:20 – Autoimmune hepatitis: limitations of current therapy; new agent 

Please see the following USPI, US ISI, EU SmPC and Canadian Product Monograph for complete LIVMARLI product information: US Important Safety Information (https://livmarli.com/important-safety-information/) US Prescribing Information (https://files.mirumpharma.com/livmarli/livmarli-prescribinginformation.pdf?_ga=2.264585739.54248471… EU SmPC (https://ec.europa.eu/health/documents/community-register/html/h1704.htm) Canadian Product Monograph (https://files.mirumpharma.com/livmarli/livmarli-product-monograph-en.pdf) Learn more about the latest research for Mirum’s investigational therapies: MRM-3379 (https://mirumpharma.com/wp-content/uploads/2025/09/FXS-NDD-2025-Mouse-Model-Poster_FINAL.pdf), volixibat in PSC (https://s29.q4cdn.com/633867992/files/doc_presentations/2024/Jun/Mirum-VISTAS-and-VANTAGE-Interim-Analysis-Results-Presentation.pdf) and PBC (https://mirumpharma.com/wp-content/uploads/2025/05/Heneghan-M-EASL-2025-VANTAGE-28-week-data-with-volixibat-in-PBC.pdf), and brelovitug (https://www.natap.org/2025/AASLD/AASLD_22.htm). LIVMARLI is also currently being evaluated in the Phase 3 EXPAND study (https://clinicaltrials.gov/study/NCT06553768) in additional settings of cholestatic pruritus. References What is hepatitis delta? Hepatitis B Foundation. Accessed January 14, 2026. https://www.hepb.org/research-and-programs/hepdeltaconnect/what-is-hepatitis-delta/ Agarwal K, Jucov A, Dobryanska M, et al. Brelovitug (BJT-778) monotherapy achieved 100% virologic response in patients with chronic hepatitis D: on treatment week 48 phase 2 study results. Presented at: AASLD 2025; November 7-11, 2025; Washington, D.C. Sagnelli C, Sagnelli E, Russo A, Pisaturo M, Occhiello L, Coppola N. HBV/HDV co-infection: epidemiological and clinical changes, recent knowledge and future challenges. Life (Basel). 2021;11(2):169. doi:10.3390/life11020169 Negro F, Lok AS. Hepatitis D: a review. JAMA. 2023;330(24):2376-2387. doi:10.1001/jama.2023.23242 Hunter J, Rivero-Arias O, Angelov A, Kim E, Fotheringham I, Leal J. Epidemiology of fragile X syndrome: A systematic review and meta‐analysis. doi:10.1002/ajmg.a.36511 See omnystudio.com/listener for privacy information.

Advancements in our understanding of primary biliary cholangitis (PBC) and new therapeutic agents have reshaped the care landscape of PBC. Listen now to learn how these developments are helping to redefine and elevate treatment goals. Topics covered include:How and when to assess treatment responseRisk factors in PBCBiochemical treatment response and fibrosis stage as predictors of transplant-free survivalDynamics of liver stiffness measurements and clinical outcomes in PBCThe importance of bilirubin and alkaline phosphatase normalizationThis episode is the first of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/44ZJ5osPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify.   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

New therapeutic agents for second-line treatment are raising the bar for primary biliary cholangitis (PBC) management. Listen now to learn how to incorporate these new agents into clinical practice and how these agents will impact attainment of treatment goals.Topics covered include:Available agents for second-line treatment of PBCAn overview of clinical trial data supporting second-line agents:Obeticholic acid (OCA)BezafibrateElafibranorSeladelparThis episode is the second of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/48MEc3rPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn how symptom management should be considered independently of PBC management, and how new therapeutic agents can help.Topics covered include:Mechanisms of pruritus and fatigue in PBCNonpharmacologic treatment optionsAn overview of clinical trial data supporting second-line agents for symptom management:BezafibrateElafibranorSeladelparInvestigational agents:VolixibatLinerixibatSetanaxibThis episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode:https://bit.ly/44ZJ5osPresenters:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologySchool of MedicineUniversity of California DavisSacramento, CaliforniaAparna Goel, MDClinical Associate Professor of MedicineDivision of Gastroenterology and HepatologyStanford UniversityPalo Alto, CaliforniaAliya F. Gulamhusein, MD, MPH, FRCPCProfessorship in PSC ResearchClinician Investigator, Toronto General HospitalAssistant Professor, University of TorontoDivision of Gastroenterology and HepatologyUniversity Health NetworkToronto, CanadaGet access to all of our new episodes by subscribing to the Decera Clinical Education Medical Specialties Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Liver Lineup: Updates & Unfiltered Insights, host Nancy Reau, MD, sits down with Kris Kowdley, MD, to discuss evolving approaches in cholestatic liver disease, with a particular focus on primary biliary cholangitis (PBC).Key episode timestamps:0:00:00 – Guest intro & evolution of PBC therapy0:07:34 – Redefining biochemical response & earlier assessment0:16:26 – OCA withdrawal & positioning PPARs/fibrates0:22:16 – Diagnosing AMA‑negative PBC0:25:58 – Genetic cholestasis panels & PFIC spectrum0:29:45 – Symptom burden, pruritus, & IBAT inhibitors0:35:17 – Bone health & closing remarks

Recent advances in primary biliary cholangitis (PBC) care have resulted in a new focus on personalized care and symptom management. Tune in to learn from patient advocate, Maria G. Morais, RN, how you can integrate patient insights and priorities into treatment plans for PBC. Topics covered include:The Canadian PBC Society Survey: Comorbidities and Treatment GoalsDefining and Achieving Goal-Driven Care for PBCRecent Advances in PBC ManagementNewer Agents for Second-line Treatment of PBCPresenters:Maria G. Morais, RNPBC Transplant PatientVP Patient AdvocacyCanadian PBC SocietyToronto, CanadaLink to full program:https://bit.ly/44ySoL3Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Listen in as Nancy Reau, MD, reviews key highlights of the most impactful primary biliary cholangitis (PBC) research and gain insights on how to apply these new advances to clinical practice. Topics covered include:Treatment GoalsLong-term Data With PPAR AgonistsInvestigational Therapies for PruritusPresenter: Nancy Reau, MDProfessor of MedicineRichard B. Capps Chair of HepatologyChief, Section of HepatologyAssociate Director, Solid Organ TransplantationRush University Medical CenterChicago, IllinoisTo download the accompanying slides, visit the program page for this episode: https://bit.ly/4b2d6YD Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Tune in to listen as expert faculty, Dr Christopher L. Bowlus and Dr Sonal Kumar, discuss recent developments in treating primary biliary cholangitis (PBC) with new and emerging agents, as well as strategies to integrate these advances into clinical practice.Topics covered include: Methods of Assessing PBC Disease ProgressionNewer Agents for Second-line Treatment of PBCPrioritizing Symptom Management and Quality of Life With PBC TreatmentPresenters:Christopher L. Bowlus, MDLena Valenta Professor and ChiefDivision of Gastroenterology and HepatologySchool of Medicine University of California Davis Sacramento, CaliforniaSonal Kumar, MD, MPHAssistant Professor of MedicineDivision of Gastroenterology and HepatologyWeill Cornell Medical CollegeNew York, New YorkLink to full program: https://bit.ly/43nHx6UGet access to all of our new podcasts by subscribing to the Decera Clinical Education Infectious Disease Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Ryan Adamsfalse

Join the PBC family as we open God's Word together this morning.

In the Terms of Service series, Brother Luke looks at the Lord’s instruction to follow him. When we think of following, we often think in terms of following directions. We follow directions to arrive at an accomplished end or desired outcome, whether it’s cooking, driving, or assembling something. When we reach the end of our …

In Galatians 6, we are told to bear one another’s burdens, and then, that we should bear our own burden. If we ever think there is a contradiction in the scripture, it can only be in our own minds. If we look closely at what Paul is teaching, we see glorious instruction on how we …

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As I continue preaching on the “one anothers” of the NT, in this message I look at how we are to be likeminded towards one another, and to receive one another, and admonish one another. 01.18.26.Likeminded.Tim.McCool

Join the PBC family as we open God's Word together this morning.

Ursodiol (ursodeoxycholic acid) is a prescription bile acid medication used to dissolve cholesterol gallstones, prevent gallstones during rapid weight loss, and treat liver diseases like primary biliary cholangitis (PBC) by reducing toxic bile acids and cholesterol production. It works by changing bile composition, making it less saturated with cholesterol, and is available as oral medication. Of course, it is also the foundational medication for treatment of diagnosed Intrahepatic Cholestasis of Pregnancy (ICP). Does this medication reduce adverse perinatal outcomes? In this episode, we will review a new study from the Green Journal, which will be out in February 2026, examining the recurrence risk for ICP using data from NY. In a patient with prior history of ICP, is there any guidance on monitoring of serum bile acids in the subsequent pregnancy before symptoms develop? We will explain. PLUS we will review the data on whether Ursodiol may hold promise in recurrence prevention or in reduction of adverse outcomes once the condition is diagnosed. Listen in for details. 1. 2019: Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, Chambers J, Hunter R, Dorling J, Williamson C, Thornton JG; PITCHES study group. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet. 2019 Sep 7;394(10201):849-860. doi: 10.1016/S0140-6736(19)31270-X. Epub 2019 Aug 1. PMID: 31378395; PMCID: PMC6739598. https://pubmed.ncbi.nlm.nih.gov/31378395/2. February 08, 2025: Rahim, Mussarat N et al. Pregnancy and the liver. The Lancet. 2021; Volume 405, Issue 10477, 498 – 513 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02351-1/fulltext3. SMFM CS 53; 20214. Rosenberg, Henri M. MD; Sarker, Minhazur R. MD; Ramos, Gladys A. MD; Bianco, Angela MD; Ferrara, Lauren MD; DeBolt, Chelsea A. MD. Intrahepatic Cholestasis of Pregnancy Recurrence in a Subsequent Pregnancy. Obstetrics & Gynecology 147(2):p 239-241, February 2026. | DOI: 10.1097/AOG.0000000000006033 https://journals.lww.com/greenjournal/fulltext/2026/02000/intrahepatic_cholestasis_of_pregnancy_recurrence.13.aspx5. Ovadia C, Sajous J, Seed PT et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2021 Jul;6(7):547-558. doi: 10.1016/S2468-1253(21)00074-1. Epub 2021 Apr 27. PMID: 33915090; PMCID: PMC8192305.6. EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy. European Association for the Study of the Liver; 2023

On our Wednesday night service, I have begun a series that looks at certain Biblical characters. The first two characters are Adam and Eve. 01.14.26.Adam.and.Eve.Tim.McCool

Continuing in the “One Anothering” series, I come to the very specific instruction on how to love one another in Christian liberty. 01.11.26.Christian.Liberty.Tim.McCool

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Matt and EzRaw discuss the latest in boxing news, including:News and Notes- Oscar De La Hoya throws down the gauntlet to Jaron Ennis and Eddie Hearn. Says Vergil Ortiz vs. Boots will have to be a 60-40 split in favor of Ortiz. Fair or foul?- Ryan García vs. Mario Barrios details to be announced on Monday. Buzz check?- Robert García says that Bam Rodriguez will fight the winner of Naoya Inoue-Junto Nakatani. What are the odds Bam actually makes the jump?- Dmitry Bivol is aiming for a spring return to the ring against Michael Eifert, according to his manager. How should boxing fans feel about this development?- Fabio Wardley targeting Tyson Fury in 2026. Is this a good fight for Fury?- Jaime Munguia joins Canelo Alvarez in turning down the IBF Super Middleweight title shot against Osleys Iglesias. Thoughts? Does anyone want smoke with the Tornado?- Zuffa Boxing officially announced Callum Walsh vs. Carlos Ocampo, as first reported by Brunch Boxing. How are we feeling about the Zuffa kickoff?- Frank Martin is pushing for a fight with IBF champion Richardson Hitchins. PBC willing to make the fight. What are the odds Hitchins takes the fight?- Curmel Moton set to return on February 28 at a Manny Pacquiao Promotions show. Thoughts on where Moton is at in his career?- Subriel Matias had his gloves rejected by the NY Athletic Commission, following a complaint from Dalton Smith's team, Rob Tebbutt reports. Will this have any effect on the fight?EZ Money Parlay of the Day, EzRaw Report Card, EzRaw Breakdown - EzRaw Report Card and EzRaw Breakdown: Subriel Matias vs. Dalton Smith, Agit Kabayel vs. Damian Knyba- Mike's Ez Money Parlay, Ezra's Raw Hard Cash and Matt's Best Bet. Booking the Territory: Boxing Draft Recap, Picks for January-February- The guys held their 3rd annual boxing draft. Who won?- The guys make their picks on this week's bouts, and more. How did they do so far?Quick Hits- The IBF to order welterweight champion Lewis Crocker to face mandatory challenger Liam Paro, Tokkers reports. Thoughts on this decision?- The IBF has granted an extension for the Frank Sanchez-Richard Torrez IBF title eliminator, as both sides work towards a deal. Who wins this potential bout?- Albert Ramirez defends his interim WBA Lightweight Heavyweight Championship against Lerrone Richards on February 5. How are we feeling about Ramirez?- Brandon Adams-Caoimhin Agyarko reach deal for IBF title eliminator in April.

In the ongoing series on the terms of discipleship, Brother Luke looks at Jesus’ commandment to follow Him. We can follow people and things for many different reasons and in many ways. In this sermon Brother Luke compares the way we ‘follow’ people on social media platforms because of our interest in what they are doing to following …

In the first message of the new year, I look at the lessons of Psalm 40. Waiting and listening to the Lord is a skill to develop. It is even harder to develop in our culture because of earbuds, music and noise blaring in restaurants and gas stations. Getting in a quiet place to wait …

In the “one another” series, I look at specific ways that the NT gives us to love one another, as Jesus instructed. 12.28.25.One.Anothering.Each.Other.Tim.McCool

In the 2nd sermon on the terms of discipleship, Brother Luke looks at Jesus’ instruction that we are to take up our cross. The cross that Jesus carried was a symbol of many things, including being a picture of the burdens that evil men place on us for being servants of the Most High God. …

In Matthew 16, we read of Jesus Christ preaching about what is expected of his disciples. In the same way an athlete or solider may be told what is expected of them as being a part of a team or army, Jesus gives clear instruction on the terms of service for his disciples. In this …

As I continue in the “one anothering” series, in this message I look at the characteristics of agape love. 12.10.25.Characteristics.of.Agape.Love.Tim.McCool