Podcasts about intestinal

Chaz and AJ started the show this morning with news from North Haven, where SWAT had been summoned and no one knew the full story. Things only got stranger, when it seemed no one from the town was calling in. (0:00) Claude Strother was on with Chaz and AJ a few months ago after surviving a Bobcat attack, and then had to deal with a cancer diagnosis. After a Tribe member called asking for an update, he was on this morning to share some good news, and a story from his town's "Intestinal and Testicle Festival." (11:55)  Howard Saffan, owner and president of the Hartford HealthCare Amphitheater was on the phone this morning to look forward to a busy summer season at the amp. (25:36)  Judge Lisa Wexler was in studio this morning, to share her thoughts on the Karen Read trial and some examples of crazy wills she's seen come through the court. (36:14) 

In this encore episode, we detail the gut-immune axis, focusing on the protective mucus layer and the role of lactoferrin in intestinal health. We discuss endogenous secretions and how lactoferrin functions as an antimicrobial, immunomodulatory, and iron-regulating glycoprotein, influencing microbial balance and intestinal barrier integrity. Additionally, we highlight lactoferrin testing and levels. We finish by going through supplementation as a phenomenal tool.Topics: 1. The Intestinal Barrier & Mucus Layer- The intestinal lumen, microbiome, mucus layer, epithelial cells, and lamina propria.- The mucus layer: antimicrobial peptides (AMPs) and secretory IgA (sIgA).- Intestinal epithelial cells including goblet cells and enterocytes.2. Immune Cells in the Gut- The lamina propria.- Macrophages, dendritic cells, neutrophils, B cells, T cells, mast cells, and more.3. Antimicrobial Peptides & Secretory IgA- AMPs and sIgA in the mucus layer regulate microbial balance and prevent pathogen adhesion.4. Lactoferrin: Functions & Sources- Iron-binding glycoprotein, antimicrobial and immunomodulatory properties.- Found in mucosal secretions, colostrum, and more.- Intestinal epithelial cells (IECs) and neutrophils.5. Lactoferrin's Role in Intestinal Health- Regulates iron absorption via lactoferrin receptors (LFR)on enterocytes.- Sequesters free iron, limiting bacterial growth, bacteriostatic.- Destabilizes bacterial membranes, cell lysis, bactericidal.6. Lactoferrin Levels- Neutrophils release lactoferrin during infection,increasing its presence in the large intestine.- Fecal lactoferrin levels.- Fecal calprotectin levels.7. Lactoferrin & Candida Overgrowth- Fungal membranes.- Aiding in the inhibition of biofilm formation.8. Lactoferrin Supplementation & Benefits- Supports gut microbiota, epithelial integrity, and immune modulation.- Bovine colostrum and as a supplement.9. Conclusion- The intestinal mucus layer is key to gut barrier function.- Lactoferrin plays a central role in microbial regulation and immune defense.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

What is intestinal ultrasound? How can it change the way we take care of our patients with inflammatory bowel disease? Dr. Bincy Abraham, Professor of Clinical Medicine at Houston Methodist and Director of the Fondren Inflammatory Bowel Disease Program, answers these questions and more in this episode of the Gut Doctor Podcast.

Je suis ravie de vous retrouver cette semaine pour parler d'un sujet absolument passionnant : notre microbiote intestinal. C'est un sujet qui m'intéresse particulièrement depuis plusieurs années maintenant. Même bien avant de me former à la naturopathie. Je me rappelle que je lisais déjà des livres sur le sujet dont le très célèbre : le charme discret de l'intestin, de Giulia Enders. Dans cet épisode, nous allons partir en voyage au cœur de notre microbiote intestinal pour comprendre ce que c'est un “microbiote”, où il se trouve et également à quoi il sert. Ressources mentionnées dans cet épisode : Collecte de selles en France - projet le French Gut - https://lefrenchgut.fr/ Épisode 51 - Aqui Ba Pla! podcast - Les liens secrets entre alimentation et santé : ce que vous devez savoir - https://aqui-ba-pla.lepodcast.fr/numero-51-les-liens-secrets-entre-alimentation-et-sante-ce-que-vous-devez-savoir Je suis Audrey Boyer, naturopathe certifiée, passionnée par l'humain et fondatrice d'Aqui Ba Pla! podcast. Retrouvez toutes mes actualités sur www.audrey-boyer.fr et sur les réseaux sociaux @natur_audrey

Jaume Segalés y los responsables de Mundo Natural hablan de salud y la flora intestinal.

Send us a text¿Sabías que la salud digestiva es clave para un óptimo rendimiento físico y mental? En este episodio, Fer Alvarado, platica con Ivonne Vargas, especialista en nutrición deportiva, sobre la fascinante relación entre la microbiota intestinal y el rendimiento deportivo. Descubre cómo evitar los problemas digestivos más comunes, aprende sobre estrategias integrales para mejorar tu salud digestiva y alcanzar tu máximo potencial. INVITADA: Ivonne Vargas es licenciada en nutrición y tiene una maestría en alto rendimiento deportivo y entrenamiento. También cuenta con estudios en neurociencias aplicadas al ejercicio. Ha trabajado con el equipo de triatlón del Real Madrid y el equipo paralímpico en Río 2016. 

#ElGranMusical | Karen Alarcón, Probióticos y sus beneficios para la salud intestinal by FM Mundo 98.1

EPISODIO 129 Modera: Dra. Laura Ofelia Olivares Guzmán. Invitados: Dr. Jesús Kazuo Yamamoto Furusho y Dr. Manuel Alejandro Martínez Vázquez.El tratamiento de la enfermedad inflamatoria intestinal (EII) ha sufrido una gran transformación tras la introducción de los fármacos biológicos. Gracias a ellos, los objetivos del tratamiento han evolucionado desde la respuesta y remisión clínica a objetivos más ambiciosos, como la remisión endoscópica o radiológica. Sin embargo, aunque los biológicos son muy eficaces, un porcentaje importante de pacientes no obtendrá una respuesta inicial o la perderá a lo largo del tiempo.Conoce por qué es importante monitorear a los pacientes con EII, qué implica la vigilancia, técnicas disponibles y estudios a realizar. 

In this encore episode, we detail the intestinal mycobiome and the mechanisms by which beneficial microbes aid in regulating opportunistic fungal species: Candida albicans. We discuss Candida overgrowth virulence and how disruptions in microbial balance, immune function, and epithelial integrity impact Candida's pathogenicity. Additionally, we discuss the role of mast cells in the lamina propria, their involvement in mucosal immunity, and how Mast Cell Activation Syndrome (MCAS) can be exacerbated by fungal dysbiosis / microbial imbalances.Topics: 1. Introduction - The intestinal mycobiome and its role in intestinal health.  - Regulating populations of opportunistic fungal species like Candida albicans.- Mast cell activation syndrome (MCAS) intro.   2. Structure of the Intestinal Barrier- The microbiome and mucus layer: microbes, mucins, antimicrobial peptides, sIgA.- The epithelial monolayer: enterocytes, goblet cells, Paneth cells, enteroendocrine cells…- Tight junction proteins and paracellular transport.- The lamina propria beneath the epithelium: immune cells and more. 3. Candida's Pathogenicity and Barrier Disruption- Exists primarily in its yeast form, regulated by microbial competition, host immune defenses, antifungal peptides.  - Secretory IgA (sIgA) and immune surveillance mechanisms help regulate fungal populations. - Chronic stress, immune suppression, and dysbiosis can deplete sIgA, increasing susceptibility to Candida proliferation.  - Environmental triggers such as immune suppression, microbial depletion, inflammatory cytokines.- Yeast-to-hyphal transition, deeper tissue invasion.  - Secreted aspartyl proteinases (SAPs), phospholipases, candidalysin: epithelial damage.- Pattern recognition receptors (PRRs) and overgrowth detection. 4. Impact of Beneficial Bacteria on Candida Overgrowth  - Beneficial bacteria compete with Candida for nutrients and epithelial adhesion sites.  - Short-chain fatty acids (SCFAs) produced by beneficial bacteria.- Depletion of beneficial bacteria removes ecological resistance, allowing Candida to proliferate unchecked.   5. Mast Cells in the Lamina Propria and Their Role in Intestinal Immunity- Mast cell location - Upon activation, mast cells release histamine, cytokines, proteases, and more that regulate gut immune responses.  - Histamine can increase gut permeability and modulate local immune activation.  - Tryptase and chymase. - Pro-inflammatory cytokines.  6. Mast Cell Activation Syndrome (MCAS) - Mast cell hyperactivation.- Environmental triggers, toxins, chronic infections, and stress. - Candida overgrowth and mast cell activation.- Addressing microbial imbalances and reducing the body's total microbial, chemical, and toxin burden.- A diverse microbiome.   7. Conclusion- Candida overgrowth and regulation via immune defenses and beneficial bacterial competition.- MCAS, root cause approach.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

En esta entrevista para MVS Noticias con Luis Cárdenas, la Doctora Francisca Martínez Silva, gastroenteróloga del Hospital Centro Médico Nacional La Raza del IMSS, habló sobre la enfermedad inflamatoria intestinal, un trastorno crónico, complejo y fluctuante que alterna brotes y remisiones.See omnystudio.com/listener for privacy information.

La nutricionista Blanca López López, de Nutriboti, nos hablado de la enfermedad de Crohn y la colitis ulcerosa, de qué alimentos tomar y cuáles no y nos ha preparado una receta con esta comida 

Únete a PHIT Hoy

La obstrucción intestinal en gatos es una emergencia médica que ocurre cuando algo bloquea parcial o completamente el paso de alimentos y líquidos en los intestinos. Si no se trata a tiempo, puede provocar necrosis intestinal, peritonitis e incluso la muerte. petfamily.co

In this encore episode, we detail the pathophysiology of intestinal methanogen overgrowth (IMO), hydrogen-dominant small intestinal bacterial overgrowth (H₂-SIBO), and hydrogen sulfide-dominant SIBO (H₂S-SIBO), discussing their mechanistic interactions and overlap. We discuss methanogenic archaea, as well hydrogen sulfide- and hydrogen-producing microbes and their contributions to altered gastrointestinal motility, epithelial barrier function, and neuromuscular signaling. We detail host endogenous defense mechanisms, including gastric acid secretion, pancreatic enzymatic activity, bile flow, intestinal motility, and more.Topics:1. Introduction- Overview of intestinal methanogen overgrowth (IMO), hydrogen sulfide-dominant SIBO, and hydrogen-dominant SIBO  - Discussion of overlap  2. Intestinal Methanogen Overgrowth (IMO)- Characterized by an overabundance of methane-producing archaea  - Methane and intestinal transit- Bloating, abdominal discomfort, constipation  - Associated with irritable bowel syndrome with constipation (IBS-C)   3. Overlap Between IMO and SIBO Subtypes- Hydrogen as a substrate for methane and/or hydrogen sulfide production- Shared potential root causes 4. Small Intestinal Bacterial Overgrowth (SIBO) and Protective Mechanisms- The small intestine remains relatively free of bacteria due to protective mechanisms  - Gastric acid secretion - Pancreatic enzymes and bile - Intestinal motility- Structural abnormalities 5. Hydrogen-Dominant SIBO - Increased hydrogen and intestinal transit- Potential symptoms, diarrhea, postprandial bloating  - Different forms of SIBO can coexist  6. Hydrogen Sulfide-Dominant SIBO - H₂S and intestinal motility- H₂S and intestinal epithelial integrity- Symptoms, associations with IBS diarrhea    7. Host Defense Mechanisms Regulating Microbial Balance- Gastric acid secretion, pancreatic enzyme activity, bile flow, intestinal motility, and more 8. Gastric Acid and Its Role in Microbial Regulation- Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor  - Chief cells secrete pepsinogen, conversion into pepsin in acidic conditions  - Gastric acid, digestion and antimicrobial defense   9. Hypochlorhydria - Low gastric acid impairs microbial defense- Reduced acidity disrupts digestion and downstream pancreatic enzyme and bile release   10. Pancreatic Enzymes and Their Role in Microbial Regulation- Pancreatic enzymes, digestion, antimicrobial activity - Enzymes modify chyme to limit fermentable substrates that fuel microbial proliferation   11. Intestinal Motility - Coordinated contractions propel food, microbes, and waste through the GI tract  - The enteric nervous system (ENS) and gut motility- The myenteric plexus controls peristalsis, while the submucosal plexus regulates secretion and absorption   12. Conclusion- Intestinal methanogen overgrowth (IMO), hydrogen-dominant SIBO, and hydrogen sulfide-dominant SIBO - Overlap in symptoms and microbial interactions  - Host defense mechanisms, including gastric acid, pancreatic enzymes, and motility  - Intestinal motility and ENS function in microbial homeostasis  - Hydrogen sulfide as a gasotransmitterGet Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Avec Charlotte Jacquet Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Especial de prebióticos y probióticos en nuestro nuevo episodio con la Nutriconista Yarilis Tovar. Descubriendo todos sus mitos y verdades. Aprenda a tomar lo realmente necesario, además cuáles son sus efectos adversos. En la conducción Efraín Cruz. Además, una receta especial llena de probióticos y prebióticos con nuestra Chef Maivette Pérez. El horóscopo y las predicciones para el cónclave con José Aparicio. Las noticias con Efraín, porque Marcos aún no aparece. Controles técnicos: Carlos González. Diseño gráfico: Marcos Campos. FUERA DE LUGAR VENEZUELA

In this episode, we highlight vitamin D₃ in gastrointestinal health, with a focus on intestinal barrier function and the gut-immune axis. We discuss how vitamin D is metabolized into its active form, 1,25-dihydroxyvitamin D, and how 1,25-dihydroxyvitamin D can support the intestinal mucosa, while highlighting the intestinal epithelium and immune cells in the lamina propria. Through this, we further detail the role of regulatory T cells in supporting immune balance and modulating immune function.Topics:1. Introduction - Highlighting intestinal barrier function and the gut-immune axis with a focus on vitamin D₃ 2. Vitamin D Synthesis and Metabolism - Skin and 7-dehydrocholesterol; dietary intake.- Transported through the bloodstream bound to vitamin D binding protein.- First hydroxylation in the liver to form 25-hydroxyvitamin D₃ (25(OH)D₃).- Testing.- Second hydroxylation in the kidney to form the active 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D₃).- Local activation also occurs. 3. Intestinal Barrier Anatomy - The intestinal epithelium forms a selectively permeable monolayer that interfaces with the gut lumen.- Covered by a mucus layer: mucins, antimicrobial peptides, secretory IgA.- Mucus layer provides physical and biochemical protection.- Tight junction proteins and paracellular permeability.- Molecules crossing the epithelium. - Disruption of tight junctions, immune cell exposure to luminal contents.- The lamina propria and Gut-Associated Lymphoid Tissue (GALT). - Maintaining tolerance while defending against pathogens.  4. Vitamin D's Role in Barrier Support and Immune Modulation - 1,25-dihydroxyvitamin D₃, tight junction integrity, immune regulation, and more.- Regulatory T Cells (Tregs) and immune balance.   5. Vitamin D₂ and D₃- D₃ (cholecalciferol) is more biologically effective and binds DBP more strongly.  6. Vitamin D Levels - Levels observed in autoimmune conditions, IBS, and more.- Symptoms.- Insufficient and excessive levels of vitamin D can be detrimental.- Multi-system.  7. Conclusion - Multifactorial: Numerous factors regulate vitamin D levels.- Gastrointestinal health root cause approach.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Tener una flora intestinal en mal estado afecta tu digestión. Descubre cómo los probióticos ayudan a restaurar el equilibrio intestinal y por qué son esenciales para sentirte bien. ¡Checa nuestro artículo! #elcoachdetusalud #bienestarnatural #salud #suplementosalimenticios #remediosnaturales #nutrientes #fitoterapia #Floraintestinal #Digestión #Probióticos°°°°°°°°°°°°°°°°°°Te invito a ver el artículo de la semana: Renueva tu flora intestinal: Descubre el poder de los Probióticoshttps://elcoachdetusalud.com/renueva-tu-flora-intestinal-descubre-el-poder-de-los-probioticos/°°°°°°°°°°°°°°°°°°Déjame saber ¿qué piensas?Comenta abajo

Send us a textA groundbreaking approach to equine intestinal motility takes center stage as Drs. Barbara Delvescovo and Marta Cercone join us to discuss their pioneering research on ultrasound-guided celiac plexus blocks in horses. Their remarkable findings reveal that this technique not only restores but actually enhances intestinal motility beyond baseline levels in normal horses—without causing discomfort.Post-operative ileus remains one of the most challenging conditions in equine medicine, significantly increasing mortality rates after colic surgery. Traditional treatments often fall short, requiring a multimodal approach with limited options. This innovative nerve block technique offers a promising new tool that equine practitioners with basic ultrasound skills can implement in their practice.The conversation takes fascinating turns as we explore the researchers' diverse backgrounds, from Marta's long-standing interest in neuromodulation to Barbara's clinical practice insights. Their journey reveals how mentorship and curiosity drive scientific discovery, perfectly captured in Marta's guiding principle: "True knowledge exists in knowing that you know nothing." They also share encouraging news for horse owners—contrary to common belief, many horses return to full athletic performance after colic surgery with modern management techniques. The team is now extending their research to clinical cases and inflammatory conditions, potentially transforming how we approach equine gastrointestinal disorders. For veterinarians seeking innovative solutions to challenging cases, this episode offers valuable insights into the intersection of regional anesthesia, ultrasonography, and equine medicine.AJVR open access article: https://doi.org/10.2460/ajvr.24.11.0328INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ? JAVMA ® : https://avma.org/JAVMAAuthors AJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® : Facebook: Journal of the American Veterinary Medical Association - JAVMA | Facebook Instagram: JAVMA (@avma_javma) • Instagram photos and videos Twitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | Facebook Instagram: AJVR (@ajvroa) • Instagram photos and videos Twitter: AJVR (@AJVROA) / Twitter JAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals

In this episode, we discuss the gut-immune axis and Small Intestinal Fungal Overgrowth (SIFO), with a mechanistic focus on immune activation and epithelial barrier disruption. We detail contributing factors to and symptoms of SIFO. We further discuss the anatomical positioning and immunological functions of mast cells within the lamina propria, highlighting mast cell activation syndrome, while detailing how SIFO and SIBO can serve as upstream triggers for mast cell activation.Topics:1. The Gut-Immune Axis and Mast Cells - The intestinal epithelium forms the innermost selective barrier, coated in a protective mucus layer.- Immediately beneath lies the lamina propria, rich in immune cells including mast cells. 2. Mast Cells in the Lamina Propria - Mast cells are positioned near nerves, capillaries, lymphatics, and epithelial cells within the lamina propria.- Their anatomical location enables rapid immune surveillance and inflammatory response.- Mast cell granules store histamine and more. 3. Mast Cell Mediators - Histamine: Biogenic amine, inflammatory signaling.- Tryptase: A serine protease.- Cytokines and lipid mediators also released upon activation. 4. Mast Cell Activation Syndrome (MCAS) - Systemic: skin, respiratory tract, cardiovascular system, nervous system, and more.- The gastrointestinal tract.- Common triggers for mast cell activation. 5. Transition to Small Intestinal Fungal Overgrowth (SIFO) - Overgrowth of fungal organisms, often candida species, within the small intestine.- Contributing factors including hypochlorhydria, slowed motility, immune suppression, disrupted bacterial populations.- Overlap: SIFO, SIBO  6. Hypochlorhydria and the Stomach's Defense Role - Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor.- HCl denatures proteins and sterilizes ingested pathogens.- Chief cells secrete pepsinogen, which becomes pepsin in acidic conditions to digest proteins.- Consequences of Reduced Gastric Acidity  7. The Role of Intestinal Motility - Enteric nervous system (ENS), myenteric and submucosal plexuses.- Coordinated contractions preventing stasis and microbial overgrowth. 8. Common Symptoms of SIFO and clinical overlap with SIBO 9. Candida and Fungal Pathophysiology in the Gut - Yeast form, regulated by microbial competition and immune defenses.- Hyphal transformation.- Degrade the mucus layer, disrupt epithelial integrity, trigger inflammation. 10. Secretory IgA and Mucosal Defense - Chronic stress, immune dysfunction, dysbiosis can lower sIgA levels and weaken mucosal immunity. 11. SIFO, SIBO, and Mast Cell Activation  12. Conclusion  - Root cause approach, multi-factorial Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

En este episodio hablamos con la psiquiatra Nayra Tenorio acerca de la microbiota y la salud intestinal. Respondimos a la pregunta ¿cómo se relacionan las inflamaciones intestinales y nuestra salud mental?Te invito a que disfrutes y compartas este episodio maravilloso.Instagram: @extravagante.mente Para acceder a talleres, mentorías para mujeres y más recursos: www.extravagantemente.comPara ordenar mi libro CAMBIA TU MENTE, lo puedes adquirir desde cualquier lugar del mundo en: https://www.buscalibre.com.co/libro-cambia-tu-mente/9786280152240/p/62898417?afiliado=fdde99807c23feeee7f8Para ordenar mi libro CARTAS A UNA JOVEN DEPRIMIDA, lo puedes adquirir desde cualquier lugar del mundo en: https://www.buscalibre.com.co/libro-cartas-a-una-joven-deprimida/9786280112800/p/55709714?afiliado=fdde99807c23feeee7f8

Las mañanas de RNE con Josep Cuní se fija, en la noticia científica, en la flora intestinal. Según un estudio preclínico dirigido por investigadores estadounidenses la microbiota o flora intestinal libera unos ácidos biliares que refuerzan la inmunidad anticancerosa. Estas estructuras recién descubiertas podrían abrir la puerta a nuevos conocimientos biológicos, sobre todo en cuanto a su interacción con los receptores humanos que detectan los ácidos biliares. Fernando Rivera Herrero, jefe del servicio de Oncología Médica del Hospital de Valdecilla de Santander y presidente del grupo cooperativo del Tratamiento de tumores digestivos, señala que este estudio "lo que significa es un avance en el conocimiento de por qué mecanismos las bacterias pueden influir en la aparición del cáncer o en la protección frente a él, pueden hacer ambas cosas". Escuchar audio

"That Time I Raided the Unconquerable Mega Dungeon"Gasp! its a Ghast...O#podcast #ttrpgs #actualplay #nerd #isekai https://www.homebrewdetritus.com/

In this encore episode, we discuss the role of histamine within the gastrointestinal tract, detailing its regulation of gastric acid secretion and impact on intestinal motility. We examine how histamine-producing enterochromaffin-like (ECL) cells, mast cells, and gut microbiota contribute to histaminergic signaling, and how enzymatic degradation via diamine oxidase (DAO) maintains homeostasis. Additionally, we discuss histamine intolerance, highlighting the impacts of dysbiosis (as well as SIBO or small intestinal bacterial overgrowth) and intestinal barrier dysfunction on DAO insufficiency and histamine accumulation.Topics: 1. Introduction to Histamine & the Gastrointestinal Tract- Role in digestion and motility- Impact of intestinal conditions such as SIBO  2. Histamine as a Biogenic Amine- Definition and classification- L-histidine and histidine decarboxylase (HDC)- Presence in various tissues, including the GI tract 3. Sources of Histamine in the Gut- Enterochromaffin-like (ECL) cells in the stomach- Mast cells in the lamina propria- Histamine-producing gut bacteria 4. Histamine's Role in Digestion & Gastric Acid Secretion- Interaction with parietal cells in the stomach- Activation of proton pumps via H₂ receptor binding- Maintenance of acidic pH for digestion- Importance of proper pH within the stomach for protecting against pathogenic microbes- Impact on downstream gut microbiota balance (e.g., SIBO) 5. Histamine & Intestinal Motility- Modulation of gut motility via H₁ and H₃ receptors- H₁ receptor activation leading to contractions (diarrhea, cramping)- H₃ receptor-mediated inhibition of neurotransmitter release (bloating, slow motility) 6. Histamine Intolerance: Definition & Mechanisms- Diamine Oxidase and histamine breakdown- DAO secretion by enterocytes (intestinal epithelial cells)- Enzymatic breakdown of histamine before absorption 7. Factors That Can Affect DAO Activity- Genetic Polymorphisms: AOC1 gene, reduced DAO expression- Cofactor Deficiencies: Copper, vitamin B6, and vitamin C as essential DAO cofactors- Importance of intestinal lining integrity for DAO production- Conditions leading to or associated with enterocyte damage- Intestinal dysbiosis and histamine accumulation- Intestinal dysbiosis & epithelial/enterocyte damage- Suppression of DAO production due to epithelial dysfunction- Small Intestinal Bacterial Overgrowth (SIBO) & Histamine 8. Symptoms of Histamine Intolerance- Gastrointestinal symptoms (bloating, gas, constipation, diarrhea, acid reflux...)- Systemic symptoms (dizziness, flushing, migraines...) 9. Identifying Potential Root Causes- Tools and supplements- Bioindividual approachThanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Jaume Segalés y los responsables de Mundo Natural nos hablan de salud y de permeabilidad intestinal.

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*Texas leads the nation in agricultural weather losses.   *Texas Panhandle topsoils are getting dry.  *The American Sheep Industry Association is asking the White House to include lamb imports in the food and agriculture tariff plans.*Extremely heavy rain caused catastrophic flooding in the Rio Grande Valley last week.  *The quality of U.S. beef is the best it's ever been. *A group of U.S. lawmakers from Texas is asking USDA to expand its efforts to prevent screwworms from reentering the country. *The final days of March brought significant rainfall to the Coastal Bend of Texas. *Intestinal parasites are a major problem for sheep and goats due to resistance to dewormers.  

El colon es la parte final del sistema digestivo. También denominado intestino grueso, se trata de un tubo encargado de extraer agua y sal antes de que sean eliminados del organismo. Es el que esta encargado de mantener un equilibrio correcto en la hidratación, a la vez que elimina residuos. En el almacenamos los desechos para luego excretarlos. Cuando no tenemos probióticos y enzimas en nuestro sistema, no podemos limpiarnos adecuadamente, esto conlleva a muchas enfermedades. Puede obtener este Programa en LA Farmacia Natural en Los Angeles, Van Nuys, Huntington Park, El Monte, Arleta, Pico Rivera, Long Beach y en Burbank o llamando a la Línea de la Salud, al 1-800-227-8428 si desean que se lo enviemos a su casa.

Jaume Segalés y los responsables de Mundo Natural nos hablan de salud y de permeabilidad intestinal aumentada.

Dans ce 15e épisode de la saison 6, nous recevons Marie-Ève Caplette, nutritionniste, pour aborder le sujet du microbiote intestinal.    Notamment, il sera question de :   Comment fonctionne le système digestif, en bref ; Qu'est-ce que le microbiote? ; Comment fonctionne t'il? ; Comment en prendre soin (fibre? probiotique? aliments fermentés...) ; Est-ce que c'est vrai que nous devrions consommer une variété différente de 30 fruits et légumes par semaine pour la santé du microbiote? ; La différence entre PRObiotique et PRÉbiotique? ; Pourquoi dit-on que le microbiote intestinal est notre 2e cerveau? ; à Quel est le lien entre microbiote et immunité? ; Et bien plus!   Bonne écoute! À écouter directement via le lecteur multimédia ci-haut ou sur Spotify, Google Podcasts et Itunes. Soutenez Infuse magazine et la production de ce podcast! Si le podcast et nos contenus vous plaisent et vous inspirent, adhérez à notre abonnement mensuel (3$/mois, sans engagement), afin de nous permettre de poursuivre notre mission, soit celle d'infuser l'envie de prendre soin de soi au quotidien. Tous les détails et exclusivités : https://infusemagazine.ca/produit/abonnement-mensuel/ || Et si vous avez des questions ou des commentaires, écrivez-nous au info@infusemagazine.ca

Lucía Prieto habla con ayuda de los especialistas de Mundo Natural de la flora intestinal, una medicina para las enfermedades neurodegenerativas.

In this episode, we detail the intestinal mycobiome and the mechanisms by which beneficial microbes aid in regulating opportunistic fungal species: Candida albicans. We discuss Candida overgrowth virulence and how disruptions in microbial balance, immune function, and epithelial integrity impact Candida's pathogenicity. Additionally, we discuss the role of mast cells in the lamina propria, their involvement in mucosal immunity, and how Mast Cell Activation Syndrome (MCAS) can be exacerbated by fungal dysbiosis / microbial imbalances.Topics: 1. Introduction - The intestinal mycobiome and its role in intestinal health.  - Regulating populations of opportunistic fungal species like Candida albicans.- Mast cell activation syndrome (MCAS) intro.   2. Structure of the Intestinal Barrier- The microbiome and mucus layer: microbes, mucins, antimicrobial peptides, sIgA.- The epithelial monolayer: enterocytes, goblet cells, Paneth cells, enteroendocrine cells…- Tight junction proteins and paracellular transport.- The lamina propria beneath the epithelium: immune cells and more. 3. Candida's Pathogenicity and Barrier Disruption- Exists primarily in its yeast form, regulated by microbial competition, host immune defenses, antifungal peptides.  - Secretory IgA (sIgA) and immune surveillance mechanisms help regulate fungal populations. - Chronic stress, immune suppression, and dysbiosis can deplete sIgA, increasing susceptibility to Candida proliferation.  - Environmental triggers such as immune suppression, microbial depletion, inflammatory cytokines.- Yeast-to-hyphal transition, deeper tissue invasion.  - Secreted aspartyl proteinases (SAPs), phospholipases, candidalysin: epithelial damage.- Pattern recognition receptors (PRRs) and overgrowth detection. 4. Impact of Beneficial Bacteria on Candida Overgrowth  - Beneficial bacteria compete with Candida for nutrients and epithelial adhesion sites.  - Short-chain fatty acids (SCFAs) produced by beneficial bacteria.- Depletion of beneficial bacteria removes ecological resistance, allowing Candida to proliferate unchecked.   5. Mast Cells in the Lamina Propria and Their Role in Intestinal Immunity- Mast cell location - Upon activation, mast cells release histamine, cytokines, proteases, and more that regulate gut immune responses.  - Histamine can increase gut permeability and modulate local immune activation.  - Tryptase and chymase. - Pro-inflammatory cytokines.  6. Mast Cell Activation Syndrome (MCAS) - Mast cell hyperactivation.- Environmental triggers, toxins, chronic infections, and stress. - Candida overgrowth and mast cell activation.- Addressing microbial imbalances and reducing the body's total microbial, chemical, and toxin burden.- A diverse microbiome.   7. Conclusion- Candida overgrowth and regulation via immune defenses and beneficial bacterial competition.- MCAS, root cause approach.Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠Peach Cider Vinegar⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Event Objectives:Define pediatric intestinal failure and evaluate its prognosis.Create a successful nutritional medical and surgical plan for children with pediatric intestinal failure.Identify remaining challenges in the treatment of pediatric intestinal failure.Claim CME Credit Here!

This episode covers intestinal obstruction.Written notes can be found at https://zerotofinals.com/paediatrics/gastro/obstruction/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

ZENcillamete es un camino práctico para redescubrir la simpleza de la vida y así experimentar la plenitud a cada instante. Roberto Cuéllar, su autor, nos comparte de qué manera podemos vivir siendo más flexibles para poder conectar con el verdadero gozo a cada paso. Un intestino feliz es un libro escrito por la doctora María Dolores de la Puerta en el que nos explica cómo la microbiota mejora nuestra salud mental y nos ayuda a entender y procesar mejor nuestro mundo emocional.

In this episode, we detail the pathophysiology of intestinal methanogen overgrowth (IMO), hydrogen-dominant small intestinal bacterial overgrowth (H₂-SIBO), and hydrogen sulfide-dominant SIBO (H₂S-SIBO), discussing their mechanistic interactions and overlap. We discuss methanogenic archaea, as well hydrogen sulfide- and hydrogen-producing microbes and their contributions to altered gastrointestinal motility, epithelial barrier function, and neuromuscular signaling. We detail host endogenous defense mechanisms, including gastric acid secretion, pancreatic enzymatic activity, bile flow, intestinal motility, and more.Topics:1. Introduction- Overview of intestinal methanogen overgrowth (IMO), hydrogen sulfide-dominant SIBO, and hydrogen-dominant SIBO  - Discussion of overlap  2. Intestinal Methanogen Overgrowth (IMO)- Characterized by an overabundance of methane-producing archaea  - Methane and intestinal transit- Bloating, abdominal discomfort, constipation  - Associated with irritable bowel syndrome with constipation (IBS-C)   3. Overlap Between IMO and SIBO Subtypes- Hydrogen as a substrate for methane and/or hydrogen sulfide production- Shared potential root causes 4. Small Intestinal Bacterial Overgrowth (SIBO) and Protective Mechanisms- The small intestine remains relatively free of bacteria due to protective mechanisms  - Gastric acid secretion - Pancreatic enzymes and bile - Intestinal motility- Structural abnormalities 5. Hydrogen-Dominant SIBO - Increased hydrogen and intestinal transit- Potential symptoms, diarrhea, postprandial bloating  - Different forms of SIBO can coexist  6. Hydrogen Sulfide-Dominant SIBO - H₂S and intestinal motility- H₂S and intestinal epithelial integrity- Symptoms, associations with IBS diarrhea    7. Host Defense Mechanisms Regulating Microbial Balance- Gastric acid secretion, pancreatic enzyme activity, bile flow, intestinal motility, and more 8. Gastric Acid and Its Role in Microbial Regulation- Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor  - Chief cells secrete pepsinogen, conversion into pepsin in acidic conditions  - Gastric acid, digestion and antimicrobial defense   9. Hypochlorhydria - Low gastric acid impairs microbial defense- Reduced acidity disrupts digestion and downstream pancreatic enzyme and bile release   10. Pancreatic Enzymes and Their Role in Microbial Regulation- Pancreatic enzymes, digestion, antimicrobial activity - Enzymes modify chyme to limit fermentable substrates that fuel microbial proliferation   11. Intestinal Motility - Coordinated contractions propel food, microbes, and waste through the GI tract  - The enteric nervous system (ENS) and gut motility- The myenteric plexus controls peristalsis, while the submucosal plexus regulates secretion and absorption   12. Conclusion- Intestinal methanogen overgrowth (IMO), hydrogen-dominant SIBO, and hydrogen sulfide-dominant SIBO - Overlap in symptoms and microbial interactions  - Host defense mechanisms, including gastric acid, pancreatic enzymes, and motility  - Intestinal motility and ENS function in microbial homeostasis  - Hydrogen sulfide as a gasotransmitterThank you to our episode sponsors:1. Shop ⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠Peach Cider Vinegar⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠. 2. Shop ⁠CYLN's⁠ full skincare line ⁠here⁠.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

A puzzling pair of Case Reports from the most recent issue of the journal. First up (1:35) is a man in his mid-fifties, presenting with lumbar spine fractures, which then developed into confusion, vomiting, and abdominal pain. An x-ray showed  dilated intestinal loops and his blood sodium levels were low. https://pn.bmj.com/content/25/1/87 The second case (23:06) involves a 21-yo woman, who presented  at 18 weeks pregnant with  multiple episodes of right upper limb tonic extension, and subsequently developed new-onset refractory status epilepticus (NORSE). https://pn.bmj.com/content/25/1/56    The case reports discussion is hosted by Prof. Martin Turner¹, who is joined by Dr. Ruth Wood² and Dr. Xin You Tai³ for a group examination of the features of each presentation, followed by a step-by-step walkthrough of how the diagnosis was made. These case reports and many others can be found in the February 2025 issue of the journal. (1) Professor of Clinical Neurology and Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, and Consultant Neurologist at John Radcliffe Hospital. (2) Neurology Registrar, University Hospitals Sussex. (3) Clinical Academic Fellow, Nuffield Department of Clinical Neurosciences, Oxford University, and Neurology Specialty registrar, Oxford University Hospital.  Please subscribe to the Practical Neurology podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3vVPClm) or Spotify (https://spoti.fi/4baxjsQ). We'd love to hear your feedback on social media - @PracticalNeurol. Production and editing by Letícia Amorim and Brian O'Toole. Thank you for listening. 

In this episode, we detail the gut-immune axis, focusing on the protective mucus layer, antimicrobial peptides, and the role of lactoferrin in intestinal health. We discuss endogenous secretions and how lactoferrin functions as an antimicrobial, immunomodulatory, and iron-regulating glycoprotein, influencing microbial balance and intestinal barrier integrity. Additionally, we highlight lactoferrin testing and levels. We finish by going through supplementation as a phenomenal tool.Topics: 1. The Intestinal Barrier & Mucus Layer- The intestinal lumen, microbiome, mucus layer, epithelial cells, and lamina propria.- The mucus layer: antimicrobial peptides (AMPs) and secretory IgA (sIgA).- Intestinal epithelial cells including goblet cells and enterocytes.2. Immune Cells in the Gut- The lamina propria.- Macrophages, dendritic cells, neutrophils, B cells, T cells, mast cells, and more.3. Antimicrobial Peptides & Secretory IgA- AMPs and sIgA in the mucus layer regulate microbial balance and prevent pathogen adhesion.4. Lactoferrin: Functions & Sources- Iron-binding glycoprotein, antimicrobial and immunomodulatory properties.- Found in mucosal secretions, colostrum, and more.- Intestinal epithelial cells (IECs) and neutrophils.5. Lactoferrin's Role in Intestinal Health- Regulates iron absorption via lactoferrin receptors (LFR)on enterocytes.- Sequesters free iron, limiting bacterial growth, bacteriostatic.- Destabilizes bacterial membranes, cell lysis, bactericidal.6. Lactoferrin Levels- Neutrophils release lactoferrin during infection,increasing its presence in the large intestine.- Fecal lactoferrin levels.- Fecal calprotectin levels.7. Lactoferrin & Candida Overgrowth- Fungal membranes.- Aiding in the inhibition of biofilm formation.8. Lactoferrin Supplementation & Benefits- Supports gut microbiota, epithelial integrity, and immunemodulation.- Bovine colostrum and as a supplement.9. Conclusion- The intestinal mucus layer is key to gut barrier function.- Lactoferrin plays a central role in microbial regulationand immune defense.Thank you to our episode sponsors:1. Shop ⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠Peach Cider Vinegar⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠here⁠⁠⁠⁠. 2. Shop CYLN's full skincare line here.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

If you're looking to lose serious weight, then you're going to want to pay close attention to this lesson. I will be sharing with you 3 fasting schedules that allow your metabolism to burn stubborn fat. Whether you've never practiced fasting before, or have been practicing fasting for years, you will benefit from this lesson. I've taken the information you're about to learn from my brand new book, Metabolic Freedom, which will be released on May 13th 2025, but you can pre order now and get $997 in FREE gifts. Let's start with the first fasting schedule, 12 hours. Lower insulin Complete digestion Redistribute blood flow (energy diversion) The second fasting schedule is 36 hours, here's what happens inside your body during this timeframe. Intestinal stem cells reboot Autophagy and mitophagy is enhanced Insulin drops significantly (serious fat loss) Muscle is preserved via growth hormone The third fasting schedule is a 48 hour fast. This resets your dopamine receptors. Scenesscent zombie cells get removed via apoptosis More fat loss is achieved through enhanced ketone production. Brain gets fired up. Inflammation and oxidative stress dramatically reduced.  Spiritual feeling. BDNF boost The ideal rotation for fat loss… You're done eating Sunday at 6pm… Continue fasting until Tuesday at 6pm (48 hour fast complete) Wednesday: eat 3 meals per day, 8am, 12pm, 6pm (12 hour fast) Thursday  eat 3 meals per day, 8am, 12pm, 6pm (12 hour fast) Friday eat 3 meals per day, 8am, 12pm, 6pm (12 hour fast) Fast from Friday 6pm until Sunday morning at 6am (36 hour fast complete), then eat at 12pm and then 6pm on Sunday. Links and Resources:

In this new episode Drs. Jason Silverman and Temara Hajjat sit down with Dr. Michael Dolinger to review intestinal ultrasound and how it will transform how we care for children with inflammatory bowel disease.Michael Dolinger, MD, is the Director of Pediatric Inflammatory Bowel Disease and an Assistant Professor of Pediatrics at NYU Grossman School of Medicine. During his fellowship training, Dr. Dolinger became the first gastroenterology fellow in the United States to be trained and certified to perform intestinal ultrasound for inflammatory bowel disease activity monitoring. He has co-founded the Intestinal Ultrasound Group of the United States and Canada (iUSCAN) and now leads global training, education, and research efforts on the use of intestinal ultrasound as a non-invasive monitoring tool in inflammatory bowel disease care.Learning objectivesReview the role for intestinal ultrasound in the diagnosis and monitoring of inflammatory bowel disease in children including its strengths and weaknesses.Discuss the training path to certification in intestinal ultrasound.Review strategies and considerations for integrating intestinal ultrasound into pediatric gastroenterology clinics.Episode linksIUS as a pre-screening tool in clinical trials IUS guide to billing and credentialing IUS to predict endoscopic healing in children with CDiUSscan.orgSupport the showThis episode may be eligible for CME credit! Once you have listened to the episode, click this link to claim your credit. Credit is available to NASPGHAN members (if you are not a member, you should probably sign up). And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Bluesky, Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.

Peau, bouche, poumon, vessie… plusieurs parties de notre corps sont occupées par un microbiote, c'est-à-dire un ensemble de bactéries, champignons et virus. C'est le cas de notre intestin qui abrite un millier d'espèces différentes de micro-organismes, principalement des bactéries. À quoi sert le microbiote intestinal ? Que se passe-t-il lorsqu'il est déséquilibré ? Comment en prendre soin ? Pr Harry Sokol, professeur en Gastro-Entérologie à l'Hôpital Saint-Antoine, à Paris et enseignant à la Faculté de Médecine de Sorbonne Université. Directeur du Centre de transplantation fécale de l'APHP, chercheur à l'Inserm et à l'INRAE et auteur de l'ouvrage Les extraordinaires pouvoirs du ventre. Un fabuleux voyage au cœur de notre microbiote, une bande dessinée illustrée par Judy, parue chez Deboeck Superieur Pr Christian Tzeuton, gastro-entérologue à l'Hôpital général de Douala au Cameroun et Centre Médical des Capucines, président d'honneur de la Société camerounaise de gastro-entérologie Bastien Corsat, délégué de l'Association AFA 75 Crohn–RCH–France. Patient atteint de la maladie de Crohn.Programmation musicale :► Olamide ; Asake – Amapinao► iZem ; Lucas Santtana – Maria Antonieta.(Rediffusion)

Peau, bouche, poumon, vessie… plusieurs parties de notre corps sont occupées par un microbiote, c'est-à-dire un ensemble de bactéries, champignons et virus. C'est le cas de notre intestin qui abrite un millier d'espèces différentes de micro-organismes, principalement des bactéries. À quoi sert le microbiote intestinal ? Que se passe-t-il lorsqu'il est déséquilibré ? Comment en prendre soin ? Pr Harry Sokol, professeur en Gastro-Entérologie à l'Hôpital Saint-Antoine, à Paris et enseignant à la Faculté de Médecine de Sorbonne Université. Directeur du Centre de transplantation fécale de l'APHP, chercheur à l'Inserm et à l'INRAE et auteur de l'ouvrage Les extraordinaires pouvoirs du ventre. Un fabuleux voyage au cœur de notre microbiote, une bande dessinée illustrée par Judy, parue chez Deboeck Superieur Pr Christian Tzeuton, gastro-entérologue à l'Hôpital général de Douala au Cameroun et Centre Médical des Capucines, président d'honneur de la Société camerounaise de gastro-entérologie Bastien Corsat, délégué de l'Association AFA 75 Crohn–RCH–France. Patient atteint de la maladie de Crohn.Programmation musicale :► Olamide ; Asake – Amapinao► iZem ; Lucas Santtana – Maria Antonieta.(Rediffusion)

Las enfermedades gastrointestinales son las terceras más comunes en México, con 3.2 millones de casos en 2022 y esto sólo de las que fueron reportadas. Por esa razón @denissephit quiso tocar el tema con el Dr. José Bandera, quien es médico especialista en Gastroenterología del Centro Médico ABC y médico adscrito al departamento de gastroenterología del Instituto Nacional de Nutrición Salvador Zubirán. En este capítulo resolverás esas dudas que te da miedo preguntar: ¿Cuántas veces debemos ir al baño? ¿En qué momento la distensión o diarrea ya es anormal? ¿Qué tanto sirven los probióticos y sobretodo, ¿Qué podemos hacer para mejorar nuestra salud intestinal?Transforma tu cuerpo y hábitos con Phit. Entrena donde quieras y desde 20 minutos diarios. Síguenos en Instagram.

In this episode, we go through the gut-immune axis and mycobiome, focusing on the mechanisms underlying intestinal fungal overgrowth. We highlight the roles of the intestinal mucus layer, intestinal epithelial cells, lamina propria, and secretory immunoglobulin A (sIgA) in maintaining homeostasis and defending against fungal overgrowth. We also detail the pathogenic transition of Candida from its commensal yeast form to an invasive hyphal state, as well as the resulting disruptions to immune function. Topics 1. Introduction to the Gut-Immune Axis and Mycobiome    - The gut-immune axis and mycobiome.    - Exploring intestinal fungal overgrowth.   2. Overview of the Gastrointestinal Lining    - Anatomy of the intestinal lining: lumen and microbiome, mucus layer, epithelial monolayer, and lamina propria.    - The dual role of the mucus layer: physical and biochemical barrier.    - Composition of mucus.   3. Goblet Cells and Mucus Production    - Goblet cells as critical producers of mucin glycoproteins and their role in mucus barrier integrity.    - Signals for mucin release, such as mechanical stress.   4. The Lamina Propria and Gut-Associated Lymphoid Tissue (GALT)    - Layers beneath the epithelium    - Peyer's patches, mesenteric lymph nodes, isolated lymphoid follicles, and intraepithelial lymphocytes.    - Immune tolerance and defense against pathogens.   5. Peyer's Patches    - Positioning of Peyer's patches.    - The transition of microbial density from the small intestine to the colon and its immune implications.   6. Immune Cells in the Lamina Propria    - Overview of macrophages, dendritic cells, mast cells, plasma cells, and lymphocytes.    - Their role in maintaining immunological equilibrium in the gut.   7. The Mycobiome and Pathogenic Transition of Candida    - Candida's transition from yeast to hyphal form.    - Regulation of Candida by microbial competition and immune surveillance.    - Factors promoting pathogenicity: immune suppression, lacking beneficial microbes, more.   8. Virulence Factors of Candida    - Secretion of hydrolytic enzymes such as SAPs and phospholipases.    - Degradation of sIgA and its consequences for immune evasion.    - Adhesins that facilitate fungal binding.   9. Intestinal Barrier Disruption by Candida    - Penetration of the mucus layer and epithelial barrier by Candida hyphae.    - Disruption of tight junctions and the resulting increased intestinal permeability.    - Inflammatory cascade triggered by fungal antigens and microbial toxins entering the lamina propria.   10. Biofilm Formation     - The role of biofilms in shielding fungal cells from immune attack and antifungal treatments.   11. Small Intestinal Fungal Overgrowth (SIFO)     - Intestinal dysmotility, low stomach acid, immunocompromise.     - Possible symptoms of SIFO.     - Discussion of the overlap between SIFO, SIBO, histamine intolerance, and other gastrointestinal conditions. - Root cause. Thank you to our episode sponsors: 1. Shop ⁠Fresh Press Farms⁠' Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection ⁠here⁠. 2. Check out ⁠⁠⁠⁠⁠Ulyana Organics'⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Tallow Wild Yam Cream⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Healing Facial Oil⁠⁠⁠⁠⁠, and use code ⁠⁠⁠⁠⁠CHLOE10⁠⁠⁠⁠⁠ 10% off your order. 3. Check out Spectrum Sciences' Serums and The Vitamin B12 Protocol here, and use code CHLOE15 for 15% off. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

On Today’s Show: 00:00:00  Introduction 02:50:13  Every City Has A Cult 08:19:23  The Mountain Dew Baja Prophecies 13:25:04  Pastor Manning Is Running For Mayor: Get Rid Of Da Poop 18:15:13  Homeless Man Pushed A Turd Through A Park Bench 23:04:01  How To Attract Women With Large Penises 28:41:24  Support Distorted View Daily 30:30:00  Sisterly Brawl […] The post Let The Scent Of Your Intestinal Mucus Drive Women Crazy first appeared on Distorted View Daily.

In this episode, we explore some of the neural and cellular mechanisms underlying gastrointestinal motility, emphasizing the roles of the enteric nervous system (ENS) and interstitial cells of Cajal (ICCs) in coordinating smooth muscle contractions throughout the digestive tract. We detail disruptions in motility seen in dysautonomia, intestinal methanogen overgrowth (IMO), and small intestinal bacterial overgrowth (SIBO). And, we finish with a brief discussion on the impacts of low stomach acid. Topics: 1. Introduction to Gastrointestinal Motility - Coordinated contractions of smooth muscle that move food, liquid, and waste through the gastrointestinal (GI) tract. - Neural, hormonal, and microbial factors. - Intestinal methanogen overgrowth (IMO) and small intestinal bacterial overgrowth (SIBO). 2. Neural Regulation of Gut Motility - The enteric nervous system (ENS) embedded in the walls of the GI tract. - The ENS, central nervous system (CNS), and vagus nerve. - The myenteric plexus governs motor control and peristalsis, while the submucosal plexus regulates secretion, absorption, and blood flow. - Stress and motility 3. Cellular Regulation of Gut Motility - Interstitial cells of Cajal (ICCs), pacemaker cells located near smooth muscle cells. - ICCs generate slow-wave electrical activity. - Acetylcholine enhances smooth muscle contraction. 4. Dysmotility and Potential Contributing Factors - Impaired ICC function, smooth muscle dysfunction, nervous system dysfunction. - Dysautonomia, a dysfunction of the autonomic nervous system. - External stressors, hormonal imbalances, and more. 5. Intestinal Methanogen Overgrowth (IMO) - Characterized by an overgrowth of methane-producing archaea in the intestines. - Excess methane production affects smooth muscle activity and can slow intestinal transit. - Symptoms such as bloating, abdominal discomfort, constipation. - Breath testing. 6. Small Intestinal Bacterial Overgrowth (SIBO) - Excessive bacterial colonization in the small intestine, disrupting normal gut function. - Protective mechanisms including stomach acid and intestinal motility. - Low stomach acid (hypochlorhydria) reduces the acidic environment needed to inhibit bacterial colonization. - Bloating, diarrhea/constipation, and more. 7. Overlap Between IMO and SIBO - Excess hydrogen produced in SIBO can serve as a substrate for methane production in IMO. - Can exacerbate each other, creating a loop that worsens symptoms. 8. Addressing Dysmotility and Overgrowth - Determining the root cause of dysmotility. - Dysmotility can involve multiple regions of the GI tract. Thank you to our episode sponsors: 1. Shop Fresh Press Farms' Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection here. 2. Check out ⁠⁠⁠⁠Ulyana Organics'⁠⁠⁠⁠ ⁠⁠⁠⁠Tallow Wild Yam Cream⁠⁠⁠⁠ and ⁠⁠⁠⁠Healing Facial Oil⁠⁠⁠⁠, and use code ⁠⁠⁠⁠CHLOE10⁠⁠⁠⁠ 10% off your order. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Todos mis recursos con descuentos, links, cursos, consultas y TODO los encuentras en este unico link solo dale click y te lleva todo https://linktr.ee/dulcedagda Episodio 213

The panelists review common conditions leading to pediatric intestinal failure. They will also discuss the importance of multidisciplinary care that children receive as patients of the UF Pediatric Intestinal Rehabilitation Program.

In this episode, we go through the role of histamine within the gastrointestinal tract, exploring its regulation of gastric acid secretion and impact on intestinal motility. We examine how histamine-producing enterochromaffin-like (ECL) cells, mast cells, and gut microbiota contribute to histaminergic signaling, and how enzymatic degradation via diamine oxidase (DAO) maintains homeostasis. Additionally, we discuss histamine intolerance, highlighting the impacts of dysbiosis (as well as SIBO or small intestinal bacterial overgrowth) and intestinal barrier dysfunction on DAO insufficiency and histamine accumulation. Topics: 1. Introduction to Histamine & the Gastrointestinal Tract Role in digestion and motility Impact of intestinal conditions such as SIBO 2. Histamine as a Biogenic Amine Definition and classification L-histidine and histidine decarboxylase (HDC) Presence in various tissues, including the GI tract 3. Sources of Histamine in the Gut Enterochromaffin-like (ECL) cells in the stomach Mast cells in the lamina propria Histamine-producing gut bacteria 4. Histamine's Role in Digestion & Gastric Acid Secretion Interaction with parietal cells in the stomach Activation of proton pumps via H₂ receptor binding Maintenance of acidic pH for digestion Importance of proper pH within the stomach for protecting against pathogenic microbes Impact on downstream gut microbiota balance (e.g., SIBO) 5. Histamine & Intestinal Motility Modulation of gut motility via H₁ and H₃ receptors H₁ receptor activation leading to contractions (diarrhea, cramping) H₃ receptor-mediated inhibition of neurotransmitter release (bloating, slow motility) 6. Histamine Intolerance: Definition & Mechanisms Diamine Oxidase and histamine breakdown DAO secretion by enterocytes (intestinal epithelial cells) Enzymatic breakdown of histamine before absorption 7. Factors That Can Affect DAO Activity Genetic Polymorphisms: AOC1 gene, reduced DAO expression Cofactor Deficiencies: Copper, vitamin B6, and vitamin C as essential DAO cofactors Importance of intestinal lining integrity for DAO production Conditions leading to or associated with enterocyte damage Intestinal dysbiosis and histamine accumulation Intestinal dysbiosis & epithelial/enterocyte damage Suppression of DAO production due to epithelial dysfunction Small Intestinal Bacterial Overgrowth (SIBO) & Histamine 8. Symptoms of Histamine Intolerance Gastrointestinal symptoms (bloating, gas, constipation, diarrhea, acid reflux...) Systemic symptoms (dizziness, flushing, migraines...) 9. Identifying Potential Root Causes Tools and supplements Bioindividual approach Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Join Revero Waitlist: https://revero.com/join Jessica overcame MMIHS, visceral myopathy, chronic urinary retention, intestinal failure, failure to thrive, and chronic constipation on the carnivore diet. Instagram: https://www.instagram.com/chealthcollective/ Twitter: https://x.com/CHealthCollect YouTube: https://youtube.com/@chealthcollect Website: https://chealthcollective.org/ Timestamps: 00:00 Trailer and introduction. 04:48 Severe digestive issues led to pseudo obstructions. 07:36 GAPS diet improved daughter's health rapidly. 12:00 Helping children worldwide with health recovery guidance. 16:29 Volvulus is life-threatening; school dietary concerns. 18:29 Careful with diet due to past trauma. 22:56 Autoimmune issues managed with a natural diet. 23:37 Improved health with keto and carnivore diet. 27:44 Carnivore diet might reduce scar tissue. 31:17 Bone broth replaces electrolytes, avoiding g-tube. 35:32 Meat-based diet improved children's behavior and cognition. 39:10 Baby's eczema treated with beef tallow, diet. 42:52 Desperation led to faith, prayer, and vows. 45:53 Carnivore diet could transform children's health outcomes. 48:22 Intestinal transplants have severe lifelong complications. 50:04 Where to find Jessica. See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . ‪#revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation   #humanfood #AnimalBased #ZeroCarb #DietCoach  #FatAdapted #Carnivore #sugarfree  ‪