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We are still talking about big pharma deals and biotech fundraising in this episode. The big news this week was Parabilis Medicines's history-making IPO. We dive into the drug developer's plans for the eye-popping $770.5 million that it raised. Next, we discuss the details of a collaboration between Merck and Protillion Biosciences to use artificial intelligence to discover multiple therapeutic candidates. Turning to some newly published research, we discuss the early results of a first-in-human clinical trial that is testing a dual vaccine against Lassa fever and rabies, a CRISPR system engineered to selectively trigger cancer cell death by chromatin shredding, and a novel mRNA delivery platform for delivering gene therapies starting with Duchenne muscular dystrophy. Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Uduak Thomas, and Fay Lin, PhD, for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base: StockWatch: Parabilis Medicines Makes Wall Street History with $770.5M IPOBy Alex Philippidis, GEN Edge, June 14, 2026Merck, Protillion Launch AI Drug Discovery Collaboration with Up-to-$510M in Milestone PaymentsBy Alex Philippidis, GEN Edge, June 16, 2026First-in-Human Trial Reports Promising Dual Lassa–Rabies Vaccine DataGEN, June 9, 2026CRISPR Shreds Undruggable Cancer Cells with PrecisionBy Fay Lin, PhD, GEN Edge, June 8, 2026New mRNA Delivery Platform Restores Muscle Function in DMD ModelsGEN, June 11, 2026Touching Base Podcast Hosted by Corinna Singleman, PhD Behind the Breakthroughs Hosted by Jonathan D. Grinstein, PhD Hosted on Acast. See acast.com/privacy for more information.
À l'occasion de la 13ᵉ édition de la conférence AFRAVIH dédiée à la lutte contre le VIH, qui se tient à Lausanne, en Suisse, nous consacrons une émission aux actualités de l'infectiologie dans le monde. Hépatite B, dengue, tuberculose, arbovirose, mpox... Les maladies infectieuses continuent de faire des ravages à l'échelle mondiale. Quelle est la situation actuelle ? Quels sont les moyens de prévention existants ? Quelles sont les prises en charge existantes ? Troisième et dernière émission, à Lausanne, à l'occasion de l'Afravih, la conférence internationale francophone dédiée à la lutte contre le VIH, les hépatites et les infections émergentes. Nous évoquons les infections qui font l'actualité et qui nécessitent à la fois surveillance rapprochée et des efforts continus en matière de prévention, de prise en charge de recherche : les arboviroses, certaines zoonoses (Mpox et fièvre de Lassa), et des infections anciennes comme la tuberculose ou l'hépatite B qui, chacune, provoque plus d'un million de décès chaque année à l'échelle planétaire. Autant de maladies qui occupent de nombreux chercheurs et cliniciens, en particulier en zone tropicale: nous leur donnons la parole. Pr Didier Koumavi Ekouévi, professeur de Santé Publique à l'Université de Lomé au Togo, chef du Département de Santé Publique Dr Ablo Prudence Wachinou, médecin pneumologue et spécialiste de la tuberculose. Maître de conférences agrégé à la faculté des Sciences de la santé à l'université d'Abomey-Calavi à Cotonou. Chef du Service Recherche et Formation au Programme National contre la Tuberculose du Bénin Pr Abdoulaye Touré, professeur de santé publique à l'université Gamal Abdel Nasser de Conakry, directeur du Centre de recherche et de formation en infectiologie de Guinée (CERFIG) Pr Placide Mbala Kingebeni, professeur à la faculté de médecine de l'université de Kinshasa. Chef de département d'Epidémiologie et Santé Globale à l'Institut National de Recherche Biomédicale, basé à Kinshasa, en République Démocratique du Congo. Programmation musicale : ► Louis Matute, Rico TK – I'll see you soon ► Yoa – Moi.
À l'occasion de la 13ᵉ édition de la conférence AFRAVIH dédiée à la lutte contre le VIH, qui se tient à Lausanne, en Suisse, nous consacrons une émission aux actualités de l'infectiologie dans le monde. Hépatite B, dengue, tuberculose, arbovirose, mpox... Les maladies infectieuses continuent de faire des ravages à l'échelle mondiale. Quelle est la situation actuelle ? Quels sont les moyens de prévention existants ? Quelles sont les prises en charge existantes ? Troisième et dernière émission, à Lausanne, à l'occasion de l'Afravih, la conférence internationale francophone dédiée à la lutte contre le VIH, les hépatites et les infections émergentes. Nous évoquons les infections qui font l'actualité et qui nécessitent à la fois surveillance rapprochée et des efforts continus en matière de prévention, de prise en charge de recherche : les arboviroses, certaines zoonoses (Mpox et fièvre de Lassa), et des infections anciennes comme la tuberculose ou l'hépatite B qui, chacune, provoque plus d'un million de décès chaque année à l'échelle planétaire. Autant de maladies qui occupent de nombreux chercheurs et cliniciens, en particulier en zone tropicale: nous leur donnons la parole. Pr Didier Koumavi Ekouévi, professeur de Santé Publique à l'Université de Lomé au Togo, chef du Département de Santé Publique Dr Ablo Prudence Wachinou, médecin pneumologue et spécialiste de la tuberculose. Maître de conférences agrégé à la faculté des Sciences de la santé à l'université d'Abomey-Calavi à Cotonou. Chef du Service Recherche et Formation au Programme National contre la Tuberculose du Bénin Pr Abdoulaye Touré, professeur de santé publique à l'université Gamal Abdel Nasser de Conakry, directeur du Centre de recherche et de formation en infectiologie de Guinée (CERFIG) Pr Placide Mbala Kingebeni, professeur à la faculté de médecine de l'université de Kinshasa. Chef de département d'Epidémiologie et Santé Globale à l'Institut National de Recherche Biomédicale, basé à Kinshasa, en République Démocratique du Congo. Programmation musicale : ► Louis Matute, Rico TK – I'll see you soon ► Yoa – Moi.
In this episode of Transmission Interrupted, host Jill Morgan of Emory University Hospital sits down with Dr. Laura Evans to discuss how U.S. healthcare systems are preparing for the unique public health challenges surrounding the upcoming 2026 FIFA World Cup. From heat-related illness and overcrowded emergency departments to infectious disease risks such as measles, influenza, COVID-19, novel influenza viruses, and endemic threats like Lassa fever, the conversation explores why preparedness for mass gatherings extends far beyond a single disease focus.Dr. Evans emphasizes the importance of situational awareness tools, including CDC resources and Boston University's Beacon platform, while reminding listeners that screening alone is never perfect. The episode highlights the continued importance of core infection prevention practices such as source control, masking when appropriate, hand hygiene, and obtaining detailed travel and exposure histories. Together, Jill Morgan and Dr. Laura Evans reinforce the principle of “identify, isolate, and inform,” discuss the value of understanding local and regional escalation pathways, and examine how World Cup planning can strengthen everyday healthcare preparedness nationwide.Questions or comments for NETEC? Contact us at info@netec.org.Visit Transmission Interrupted on the web.GuestLaura Evans, MD, MScExecutive Director of the National Special Pathogen System (NSPS) Dr. Evans is a Professor of Medicine at the University of Washington and the former Medical Director of Critical Care at the University of Washington Medical Center. Her clinical and scholarly interests focus on preparedness for HCIDs and sepsis. Before joining the University of Washington faculty, she was the Medical Director of Critical Care at NYC Health + Hospitals/Bellevue, where she helped found the Special Pathogens Program. From 2014 to 2019, Dr. Evans served as the inaugural Co-Principal Investigator of NETEC at NYC Health + Hospitals/Bellevue.HostJill Morgan, RNEmory Healthcare, Atlanta, GAJill Morgan is a registered nurse and a subject matter expert in personal protective equipment (PPE) for NETEC. For 35 years, Jill has been an emergency department and critical care nurse, and now splits her time between education for NETEC and clinical research, most of it centering around infection prevention and personal protective equipment. She is a member of the Association for Professionals in Infection Control and Epidemiology (APIC), ASTM International, and the Association for the Advancement of Medical Instrumentation (AAMI).ResourcesBeaconNETEC Resource LibraryTransmission Interrupted PodcastNSPSNETECAbout NETECA Partnership for PreparednessThe National Emerging Special Pathogens Training and Education Center's mission is to set the gold standard for special pathogen preparedness and response across health systems in the U.S. with the goals of driving best practices, closing knowledge gaps, and developing innovative resources.Our vision is a sustainable infrastructure and culture of readiness for managing suspected and confirmed special pathogen incidents across the United States public health and health care delivery systems.For more information visit NETEC on the web at www.netec.org.NETEC Consultation ServicesAssess and Advance Your Readiness for Special Pathogens with Free, Expert Consulting.NETEC offers free virtual and onsite readiness consulting to help health care facilities and EMS agencies prepare for special pathogen events. Our targeted support services are delivered by experts selected and assigned to each inquiry based on the unique needs of your organization. Have a question? Ask a NETEC expert.For more information visit: netec.org/consulting-services.
Programa 14/04/26: Conversamos con Erika López, trabajadora social de LASSA, sobre los servicios y programas de apoyo que brinda esta organización sin fines de lucro a migrantes y refugiados latinoamericanos en Australia del Sur; un experto en Medio Oriente analiza la situación y explica quiénes son los ganadores y perdedores del conflicto; te traemos un informe sobre las elecciones en Perú que tendrían un balotaje.
Latin American Society of South Australia (LASSA) es una organización sin fines de lucro dedicada a conectar y empoderar a la comunidad latinoamericana en Australia del Sur. Conversamos con la trabajadora social Erika López sobre los programas disponibles y el acceso a estos servicios.
Lassa fever is back in the headlines and in hospitals.As Nigeria moves deeper into 2026, fresh data from the Nigeria Centre for Disease Control and Prevention shows a troubling rise in confirmed cases and deaths across several states. Behind the numbers are families grieving, health workers under pressure, and communities once again confronting a disease that has become a seasonal threat.Why are infections increasing? Are response efforts enough? And what must Nigerians do differently this time?Today on Nigeria Daily, we unpack the rising cases, the government's response, and what this means for you.
Någon är tänd, en annan ger dåliga tv-tips och sen bråkas det om vem som är yngst och coolast. Men varför har inte Louise lyssnat på Julias feedback?Tack till Under your skin för veckans poddspons. Kod LJ20.
Welcome to a brand-new episode of Transmission Interrupted. Today, host Jill Morgan welcomes two seasoned experts, Stefanie Lane and Michael Carr, to dive deep into the critical—and often overlooked—interface between hospitals and EMS teams during the transfer of high-consequence infectious disease patients. Whether it's a suspected case of Ebola, Lassa fever, or MERS, this episode explores the intricate choreography required for safely moving these patients between facilities. Drawing from firsthand experience and lessons learned at institutions like Emory University Hospital and Massachusetts General Hospital, our guests unpack everything from EMS operational readiness and ambulance preparation to hospital infrastructure planning and waste management. Along the way, they shine a spotlight on the importance of communication, training, and forward-thinking collaboration to keep both providers and patients safe. If you work in healthcare, emergency medicine, or are just curious about what it really takes to transfer a patient with a high-risk pathogen, this episode is packed with practical tips, cautionary tales, and valuable resources. Get ready for an honest, informative look at the pivotal moments when hospital and EMS worlds intersect. Questions or comments for NETEC? Contact us at info@netec.org. Visit Transmission Interrupted on the web at netec.org/podcast. Guests Michael Carr MD, FACEP, FAEMS Emory University School of Medicine Department of Emergency Medicine Prehospital and Disaster Section Stefanie Lane MS, MPH Assistant Director, Biothreats Program Center for Disaster Medicine Massachusetts General Hospital Host Jill Morgan, RN Emory Healthcare, Atlanta, GA Jill Morgan is a registered nurse and a subject matter expert in personal protective equipment (PPE) for NETEC. For 35 years, Jill has been an emergency department and critical care nurse, and now splits her time between education for NETEC and clinical research, most of it centering around infection prevention and personal protective equipment. She is a member of the Association for Professionals in Infection Control and Epidemiology (APIC), ASTM International, and the Association for the Advancement of Medical Instrumentation (AAMI). Resources NETEC EMS Biosafety Transport for Operators course EMS Infectious Disease Playbook NETEC Emergency Medical Services (EMS) Featured Resources NETEC Emergency Medical Services (EMS) Readiness Assessment Transmission Interrupted Podcast NETEC Resource Library About NETEC A Partnership for Preparedness The National Emerging Special Pathogens Training and Education Center's mission is to set the gold standard for special pathogen preparedness and response across health systems in the U.S. with the goals of driving best practices, closing knowledge gaps, and developing innovative resources. Our vision is a sustainable infrastructure and culture of readiness for managing suspected and confirmed special
In Nigeria, fever is a household name – from malaria to typhoid, it's one of the most common reasons people visit clinics, miss work, or reach for self-medication.But there's one kind of fever that hides in plain sight — Lassa fever.How can you tell the difference between malaria, typhoid, and something far more dangerous?This is what we set to find out in today's episode of Nigeria Daily.
Send The Parable Podcast a TextHave you ever told God, this is your problem? If you like hearing people's stories and being encouraged about the ways God is working in their lives, you have found a home right here at The Parable Podcast. Meet Liz Lassa, speaker and author of The Spiritual Circle Journal, who shares about her journey of faith, the importance of journaling, and how to connect with God amidst the chaos of life. Liz shares her personal experiences with grief, the role of community support, and practical ways to help those navigating loss. Our conversation emphasizes the significance of listening to the Holy Spirit and finding time for God in busy lives, plus offering encouragement for those seeking their calling. I hope you are encouraged to think about your own story and remember your parable showcases how we can see God through all the practices of our lives.Reflection QuestionsAre you starting a new normal, like Liz? If so, I'd love for you to take a moment to give yourself the permission that your faith life may not look the same as it did before.Have there been any recent coincidences that you can now recognize God's movement in your life, and maybe take a moment to journal about that?Connect with LizWebsite | The Spiritual Circle Journal | InstagramJournaling through GriefKeywords: spiritual growth, journaling, grief, community support, Holy Spirit, busy lives, finding God, personal stories, encouragement, faithSupport the showWays to Support The Parable Podcast #1 Subscribe or Follow the podcast to ensure you catch every episode of The Parable Podcast on your preferred podcast platform (such as iTunes, Spotify). #2 Recommend this podcast to a friend, providing a great chance to begin your own Parable Conversation. #3 Looking for a speaker for your Church, Women's Group, or event? Contact Danielle to learn more.
This episode of Transmission Interrupted dives deep into the fascinating world of seasonal special pathogens, exploring the reasons why certain infectious diseases emerge and surge at specific times of year. Host Jill Morgan is joined by Dr. Susan McLellan and Dr. Lindsay Busch, two experts in infectious diseases and biocontainment, for a captivating discussion on Nipah virus and Lassa fever. From emergency rooms filled during flu season to the quirky, unexpected ways that bats and rodents drive outbreaks in far-off regions, our guests break down what makes these pathogens so unique. Learn how cultural practices, environmental changes, and climate can influence the risk of transmission, and why understanding "One Health" and anthropology is vital for outbreak control. Perfect for clinicians, public health enthusiasts, and anyone curious about how diseases move through populations, this episode offers practical insight into recognizing risk factors, travel histories, and how global disease surveillance impacts communities everywhere. Packed with real-world stories, unexpected facts, and expert advice for spotting and responding to these high-consequence infections, this episode is not to be missed. Subscribe to Transmission Interrupted for more episodes and resources: netec.org/podcast Questions or ideas for future shows? Email us at info@netec.org. Guests Lindsay Busch, MD Assistant Professor, Medicine, Emory University School of Medicine Associate Medical Director, Emory University Serious Communicable Diseases Unit Critical Care Liaison, Emory Serious Communicable Diseases Program Susan McLellan MD, MPH Director, Special Pathogens Excellence in Clinical Treatment, Readiness, and Education (SPECTRE) University of Texas Medical Branch Host Jill Morgan, RN Emory Healthcare, Atlanta, GA Jill Morgan is a registered nurse and a subject matter expert in personal protective equipment (PPE) for NETEC. For 35 years, Jill has been an emergency department and critical care nurse, and now splits her time between education for NETEC and clinical research, most of it centering around infection prevention and personal protective equipment. She is a member of the Association for Professionals in Infection Control and Epidemiology (APIC), ASTM International, and the Association for the Advancement of Medical Instrumentation (AAMI). Resources Lassa Fever resources at NETECNipah resources at NETECTransmission Interrupted PodcastNETEC YouTubeSign up for NETEC's Email Newsletter About NETEC A Partnership for Preparedness The National Emerging Special Pathogens Training and Education Center's mission is to set the gold standard for special pathogen preparedness and response across health systems in the U.S. with the goals of driving best practices, closing knowledge gaps, and developing innovative resources. Our vision is a sustainable infrastructure and culture of readiness for managing suspected and confirmed special pathogen incidents...
In this episode, we discuss long-term outcomes after chest-wall irradiation for breast cancer, new treatments for psoriasis and obesity, and early results on a vaccine for Lassa fever. We review opioid deprescribing and a clinical case describes spiraling into a distant past. Perspectives examine the corporatization of health care, the health effects of new energy legislation, and Medicaid cuts affecting U.S. children.
V petek, 26. 9. 2025, se je v Cankarjevem domu v Ljubljani začela nova sezona za Srebrni abonma. Na uvodnem koncertu sezone je navdušil priznani britanski zbor Tenebrae, ki ga že četrt stoletja vodi njegov ustanovitelj Nigel Short. Zbor je predstavil program z naslovom Nebeško darilo v katerem je prepletal znane in manj znane mojstrovine 16. stoletja z glasbo polpretekle dobe in našega časa. Zbor Tenebrae velja za enega najuglednejših a cappella sestavov na svetu. Predstavlja se z izvirnimi programi z glasbo vse od 16. stoletja do našega časa in pri tem uspešno spleta zdaj bolj zdaj manj očitne vsebinske niti. Pod naslovom Nebeško darilo nas je v Gallusovi dvorani Cankarjevega doma popeljal na edinstveno glasbeno popotovanje skozi stoletja sakralne glasbe, začenši z motetom Musica Dei donum optimi Orlanda di Lassa, ki mu je najprej sledil gregorijanski koral Pange lingua, temu pa še preplet raznorodnih uglasbitev od renesanse do danes. Prvi del koncerta je sklenila Allegrijeva znamenita uglasbitev psalma Miserere mei Deus. Zbor Tenebrae je navduševal z zvokovno in intonačno izčiščenostjo, izrazno globino, ki je segala od intimnega prelivanja glasov v polifonskih odsekih do presunljive moči v homofonem zborovskem stavku, ter sijočo zlitostjo petnajstih pevcev v eno, na vseh področjih poenoteno izvajalsko telo. S subtilnimi, skoraj poduhovljenimi gestami ga je vodil Nigel Short, ki je večji del druge polovice programa namenil Giovanniju Pierluigiju da Palestrini ob njegovi 500. obletnici rojstva. Slišali smo štiri Palestrinova dela, zatem še MacMillanov Miserere, spored pa je kot poklon renesančni polifoniji smiselno zaokrožil motet Nunc dimittis Gustava Holsta. Zbor Tenebrae in Nigel Short sta za svoj nastop prejela stoječe ovacije, zbrano občinstvo pa pravcato glasbeno darilo, ki človeka nagovori, ga napelje k razmisleku in hkrati predrami marsikatere čute.
The Carousel is an episodic narrative podcast with sci-fi, fantasy and dystopia elements, set far enough into the future, space expansion is the norm, following a lonely worker, who uses powers he gains from an ancient carousel to fight against the corporate entity he once worked for. Episode 1: On a routine run for The Commission, Akhos, a Collections Specialist, stumbles upon an abandoned amusement park that has more to offer than he thinks. THE CAROUSELOn a desolate planet, Collections Specialist Akhos gains great powers from an ancient carousel, consequently stumbling upon a burgeoning revolution, led by The Obstructionists, against the corporate entity, The Commission, he once worked for. With his AI, Lassa and his new found powers to help his journey, Akhos fights horrific monsters with The Obstructionists after seeing they are helmed by a fellow Commission worker, Klaus. The series almost mirrors the style of a Greek Tragedy, told with the help of the Narrator, who just might have her own stake in the story told. Season One follows Akhos throughout his journey of gaining powers, joining The Obstructionists to fight against The Commission draining planets with The Machine, a mysterious device that gives the company its power, and learning why they inflict so much horror on the universe.Website: https://thenormies.com/the-carousel/Patreon: https://www.patreon.com/cw/thenormies/homeFourthwall: https://the-normies-shop.fourthwall.com/supportersYoutube: https://www.youtube.com/channel/UCbv2OBLeYiYe7B6WgPDnLowThe Carousel YouTube Playlist: https://www.youtube.com/playlist?list=PLbZ4CA8my7fSq6f-dBVihCKT48ZrzNw7tSocials: Instagram - the_normies X - The_Normies TikTok - thenormies Hosted on Acast. See acast.com/privacy for more information.
In Nigeria, fever is a household name – from malaria to typhoid, it's one of the most common reasons people visit clinics, miss work, or reach for self-medication.But there's one kind of fever that hides in plain sight — Lassa fever.How can you tell the difference between malaria, typhoid, and something far more dangerous?This is what we set to find out in today's episode of Nigeria Daily.
On this episode we are joined by Sara Zufan to discuss her PhD journey and recent projects. The episode covers various research experiences and challenges in the field, including the rapid detection of AMR using nanopore sequencing, COVID-19 projects, hepatitis A outbreak investigations, and Lassa virus surveillance in Liberia. The guests share insights into their professional journeys, their experiences working across different continents, and the future of microbial bioinformatics research.
On this episode of Transmission Interrupted, host Jill Morgan of Emory University Hospital is joined by Jade Flinn from Johns Hopkins Hospital and waste management experts Ashley Perry from Daniels Health, and Alex Chapman and Cara Simaga from Stericycle. Together, they unpack the practical and regulatory challenges of managing “Category A” infectious waste generated during the care of patients with special pathogens like Ebola, Marburg, and Lassa fever.Drawing from real-world experience, including a recent Lassa fever case, the panel explores communication breakdowns, the complexities of regulatory compliance, and the critical importance of cross-functional preparedness. They clarify what qualifies as Category A waste, how it differs from routine medical waste, and the meticulous multi-step process required for safe containment, packaging, and disposal.The discussion also highlights key takeaways from recent Joint Commission standards, the necessity of engaging waste vendors before an incident occurs, and actionable strategies to reduce risk—from the patient's bedside to final disposal.Packed with practical guidance and expert insight, this episode is a must-listen for infection prevention, emergency preparedness, and clinical teams aiming to stay ready, protect staff, and safeguard their communities.Questions or comments for NETEC? Contact us at info@netec.org.Visit Transmission Interrupted on the web at netec.org/podcast.GuestsAlex ChapmanDirector of Regulatory AffairsStericycleJade Flinn, MSN, RN, CCRN, CNRN Director of Operations, Special Pathogens Center, Biocontainment Unit The Johns Hopkins Hospital Ashley PerryDirector, Hazardous Waste ServicesDaniels HealthCara Simaga, CHMMSenior Director, Regulatory AffairsStericycleHostJill Morgan, RNEmory Healthcare, Atlanta, GAJill Morgan is a registered nurse and a subject matter expert in personal protective equipment (PPE) for NETEC. For 35 years, Jill has been an emergency department and critical care nurse, and now splits her time between education for NETEC and clinical research, most of it centering around infection prevention and personal protective equipment. She is a member of the Association for Professionals in Infection Control and Epidemiology (APIC), ASTM International, and the Association for the Advancement of Medical Instrumentation (AAMI).ResourcesDaniels Health: Ebola & Other Category A Infectious Waste Daniels Health: Ebola Packaging Kit Instructions (PDF)PHMSADOT: Planning Guidance for Handling Category A Solid WastePHMSADOT: DOT Special Permit 16279Stericycle: Ebola Waste PreparednessStericycle:
In this conversation, Dennis and Ryan Maves delve into the complex world of hemorrhagic fevers, discussing various viral infections such as Ebola, Lassa fever, and dengue. They explore the symptoms, diagnosis, and treatment options available for these dangerous pathogens, emphasizing the importance of supportive care and proper waste management. The discussion also highlights the challenges faced in resource-limited settings and the need for medical intelligence and preparedness when dealing with potential outbreaks.TakeawaysViral hemorrhagic fevers are highly dangerous pathogens.Ebola is a prototype for understanding these diseases.Symptoms often start as nonspecific febrile illnesses.Diagnosis can be challenging due to overlapping symptoms.Supportive care is crucial for patient survival.Fluid management is a key aspect of treatment.Preventative measures are essential in endemic areas.Waste management is critical in handling infected materials.Medical intelligence plays a vital role in outbreak preparedness.Expertise and resources are available for managing these diseases.Chapters00:00 Introduction to Hemorrhagic Fevers03:07 Understanding Viral Hemorrhagic Fevers05:48 Symptoms and Diagnosis of Hemorrhagic Fevers14:46 Treatment and Supportive Care24:01 Preventative Measures and Waste Management32:00 Expertise and Resources for CareThank you to Delta Development Team for in part, sponsoring this podcast.deltadevteam.comFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Mpox, Ebola, VIH, fièvre de Lassa... Nous faisons un point sur les maladies infectieuses émergentes au niveau mondial et sur les défis de la recherche internationale. Quels sont aujourd'hui les virus et maladies infectieuses qui font l'objet d'études dans le cadre de recherches de nouveaux vaccins ? Certaines études lancées ont-elles concrètement permis de contenir des épidémies ? Dr Eric D'Ortenzio, médecin, épidémiologiste, Inserm / ANRS Maladies infectieuses émergentes Retrouvez l'émission en entier ici : Maladies infectieuses émergentes : les défis de la recherche internationale
Mpox, Ebola, VIH, fièvre de Lassa…. Nous faisons un point sur les maladies infectieuses émergentes au niveau mondial et sur les défis de la recherche internationale. Quelles sont les épidémies en cours dans le monde ? Comment les chercheurs s'organisent et mettent en commun leur travail ? Comment améliorer cette collaboration pour une meilleure prise en charge des épidémies, en dépit de la volte-face de l'un des acteurs majeurs – les États-Unis – de la lutte contre les épidémies, à l'échelle mondiale ? Dr Eric D'ORTENZIO, Médecin, Épidémiologiste, Inserm / ANRS Maladies infectieuses émergentes. Dr Eddy KINGANDA LUSAMAKI, Médecin Chercheur à l'Université de Kinshasa et l'Institut National de Recherche Biomédicale (INRB) à Kinshasa en RDC et post-doc à l'unité TransVIHMI à l'Institut de Recherche pour le Développement à Montpellier en France Dr Didier Koumavi EKOUEVI, Professeur de Santé Publique à l'Université de Lomé au Togo, Chef du Département de Santé Publique. Dr Mireille MPOUDI, médecin infectiologue-épidémiologiste au ministère de la Défense du Cameroun Programmation musicale :► Boypee, Brown Joel, Hyce – Another day ► Sandalia de prata, Uli Costa – Roupa de tirar
Mpox, Ebola, VIH, fièvre de Lassa…. Nous faisons un point sur les maladies infectieuses émergentes au niveau mondial et sur les défis de la recherche internationale. Quelles sont les épidémies en cours dans le monde ? Comment les chercheurs s'organisent et mettent en commun leur travail ? Comment améliorer cette collaboration pour une meilleure prise en charge des épidémies, en dépit de la volte-face de l'un des acteurs majeurs – les États-Unis – de la lutte contre les épidémies, à l'échelle mondiale ? Dr Eric D'ORTENZIO, Médecin, Épidémiologiste, Inserm / ANRS Maladies infectieuses émergentes. Dr Eddy KINGANDA LUSAMAKI, Médecin Chercheur à l'Université de Kinshasa et l'Institut National de Recherche Biomédicale (INRB) à Kinshasa en RDC et post-doc à l'unité TransVIHMI à l'Institut de Recherche pour le Développement à Montpellier en France Dr Didier Koumavi EKOUEVI, Professeur de Santé Publique à l'Université de Lomé au Togo, Chef du Département de Santé Publique. Dr Mireille MPOUDI, médecin infectiologue-épidémiologiste au ministère de la Défense du Cameroun Programmation musicale :► Boypee, Brown Joel, Hyce – Another day ► Sandalia de prata, Uli Costa – Roupa de tirar
It's a rough time for people who worry about infectious diseases. A new study shows bird flu is more widespread in U.S. cows than previously thought. Around 250 Americans have been infected with measles, including two people who died. And globally, the Democratic Republic of the Congo is struggling to contain a Mpox outbreak, Uganda is battling Ebola, Tanzania is fighting Marburg, and Lassa fever is spreading in East Africa. In the face of all that, the Trump administration has gutted funding for programs that help protect Americans from these types of diseases. Anne Rimoin, an epidemiology professor at UCLA and director of the Center for Global and Immigrant Health, talks about what's worrying her.And in headlines: Senate Democrats said they'll vote against a House bill to keep the government open past Friday, new government data showed egg prices hit another record last month, and President Donald Trump hosted the Irish Prime at the White House amid a growing trade war with the European Union.Show Notes:Subscribe to the What A Day Newsletter – https://tinyurl.com/3kk4nyz8Support victims of the fire – votesaveamerica.com/reliefWhat A Day – YouTube – https://www.youtube.com/@whatadaypodcastFollow us on Instagram – https://www.instagram.com/crookedmedia/For a transcript of this episode, please visit crooked.com/whataday
Lisette Oropesa Lawrence Brownlee Corrado Rovaris Opéra national de la Bastille In-house recording 7 February 2025
In this episode of EMS One-Stop, host Rob Lawrence welcomes back Dr. Alex Isakov, a leading expert in infectious diseases from NETEC and Emory University in Atlanta. Dr. Isakov provides valuable updates on current and emerging infectious diseases; their global impact; and the critical role EMS professionals play in identifying, isolating and protecting themselves and their patients. This discussion highlights key infectious diseases, including H5N1 (avian flu/bird flu), Mpox (previously known as monkeypox), Ebola, Marburg, Lassa fever and seasonal flu, providing EMS personnel with essential knowledge and safety protocols in light of ongoing global health concerns. Throughout the episode, Dr. Isakov offers insights into the latest outbreaks, the importance of vaccinations, and strategies for responding to potential infectious disease threats. He stresses the necessity of remaining vigilant and prepared for high-consequence diseases while maintaining optimal patient care. From the evolving threat of H5N1 to the resurgence of seasonal influenza, Dr. Isakov ensures that EMS professionals are equipped with the most relevant and up-to-date information needed to protect both themselves and their communities. Summary of key infectious diseases covered by Dr. Isakov H5N1 (avian influenza/bird flu): Dr. Isakov provides an update on the H5N1 outbreak in poultry and dairy herds, stressing the importance of limiting human exposure and watching for potential mutations that could lead to human-to-human transmission. Mpox (Clade 1B): Dr. Isakov discusses the risk of Mpox, particularly Clade 1B, which remains prevalent in Central Africa but has now spread to other countries, including the United States. He highlights the importance of identifying travel history and unusual rashes, along with strict protective measures for EMS clinicians. Ebola and Marburg: These diseases continue to present a risk, with smaller outbreaks currently ongoing in Uganda (Ebola) and Tanzania (Marburg). Dr. Isakov notes the importance of being prepared to identify and isolate individuals who may have been exposed during travel to these regions. Lassa fever: Dr. Isakov points out the ongoing concern of Lassa fever in West Africa and emphasizes that EMS professionals should be on alert for symptoms in travelers who have visited affected regions. Seasonal influenza: The seasonal flu outbreak is particularly severe this year, and Dr. Isakov underscores the importance of vaccination, especially for vulnerable populations, to reduce serious illness and hospital strain. Timeline 00:00 – Introduction to the episode and guest, Dr. Alex Isakov 01:33 – Uupdate on Mpox (Clade 1B) and its global spread 05:24 – Ebola and Marburg outbreaks: ongoing concerns in Uganda and Tanzania 08:01 – Lassa Fever in West Africa and its impact on EMS professionals 13:05 – The importance of travel vaccinations for high-risk areas like malaria zones 15:13 – Mystery illness in the Democratic Republic of Congo and the investigation into its cause 17:01 – H5N1 and avian influenza concerns, including potential human transmission risks 22:02 – Severity of the current seasonal flu outbreak and vaccination recommendations 25:24 – EMS community's role in flu and measles vaccination advocacy 29:05 – Discussing surge conditions and excess mortality during pandemics 32:01 – Closing remarks, including updates on new NITEC EMS resources Additional infectious disease resources National Emerging Special Pathogens Training & Education Center Emergency Medical Services (EMS) Featured Resources | NETEC Symptoms of Malaria | Malaria | CDC Lassa Fever Suspected in Death of U.S. Traveler Returning from West Africa | CDC Newsroom CDC A(H5N1) Bird Flu Response Update February 26, 2025 | Bird Flu | CDC Mpox | Mpox | CDC Healthcare Workers: Could it be Ebola?
Der Virologe Florian Krammer über die verdrängte Corona-Pandemie. Ein Podcast vom Pragmaticus. Das Thema:Wissen Sie, wieviele Menschen durch SARS-CoV-2 gestorben sind? 27 Millionen. Der Impfstoffforscher Florian Krammer blickt deshalb kritisch auf die Coronavirus-Pandemie zurück. Aber vor allem nach vorn: Während wir die Pandemie-Maßnahmen problematisieren, zum Teil zu Recht, vergessen wir, uns auf die nächste Pandemie vorzubereiten, sagt er.Unser Gast in dieser Folge: Florian Krammer ist Professor für Infektionsmedizin an der Medizinischen Universität Wien, Direktor des universitätsübergreifenden Ignaz-Semmelweis-Instituts und forscht am Institut für Mikrobiologie der Icahn School of Medicine an Impfstoffen gegen Influenza-, Corona-, Lassa-, Hanta- und Ebolaviren. Er ist Professor für Vakzinologie und Principal Investigator am dortigen CIVIC-Center, das sich auf die Entwicklung von (universellen) Influenza-Impfstoffen spezialisiert hat, sowie Ko-Direktor des Center for Vaccine Research and Pandemic Preparedness (C-VaRPP). In Wien arbeitet Krammer an der Charakterisierung von Krankheitserregern, insbesondere von Viren mit pandemischem Potenzial. Für den Pragmaticus schrieb Krammer einen Beitrag über die Tücken der Erforschung von Impfstoffen sowie über das Potenzial von Influenza-Viren eine Pandemie auszulösen.Dies ist ein Podcast von Der Pragmaticus. Sie finden uns auch auf Instagram, Facebook, LinkedIn und X (Twitter).
Happy Holidays, Constructs! What a year 2024 has been for us all! We're so grateful for the TLT community and for all of you who tuned into the show this year and helped spread the word! In this episode we wrap up Act 2 of HtN covering chapters 20-22! We hope you have a safe and spectacular holiday! Let us know what you think of the episode and we'll catch you on the flipside of 2025! Art Mentioned: Harrow and Ortus with umbrella - morganida.tumblr.com Happy Holidays and stay wicked! The Bone Squad Find Us Here! https://linktr.ee/theunlockedtomb The Unlocked Tomb Podcast Artwork by: Marceline_Art - https://www.instagram.com/marceline2174 - https://linktr.ee/marceline2174 Featuring Original Music by: Chelsea Lankes - Ghost© (Remix by Dance with the Dead (Permission for use granted by the artist) Ambient Music by UNIVERSFIELD© (Permission for use granted by the artist) Soularflair - Cue 3 - Dark-Brooding© (Permission for use granted by the artist) ROZKOL - Gather Your Remnants© (Permission for use granted by the artist) ROZKOL - SAMSARA© (Permission for use granted by the artist)
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Il y a dix ans, la Sierra Leone vivait un cauchemar, balayée par l'une des épidémies les plus meurtrières de notre époque. Ebola a fauché plus de 11 000 vies en Afrique de l'Ouest, dont près de 4 000 en Sierra Leone, semant la terreur au-delà des frontières. Si le virus semble endormi, la résurgence de cas en Guinée en 2021 a ravivé les craintes. Aujourd'hui, alors qu'une campagne de vaccination préventive vise à protéger les travailleurs en première ligne, le souvenir de cette tragédie reste vif, porté par des survivants comme Daddy Hassan Kamara et Victoria Yillia, dont les récits résonnent encore. Entre mémoire collective et espoir scientifique, la Sierra Leone cherche à se relever, tout en veillant à ce que l'histoire ne se répète pas. Dans l'arrière-cour d'une petite maison à Masiaka, petite ville nichée à une heure de Freetown, Daddy Hassan Kamara fait défiler les portraits de ses proches disparus. « Voici ma mère, elle a été la première infectée par le virus après un mauvais diagnostic du médecin », raconte ce survivant d'Ebola, le regard perdu dans ses souvenirs. Ignorant qu'elle souffrait d'Ebola, il l'a soignée à mains nues, sans protection, contractant le virus à son tour.« Un jour, des gens sont venus me voir. Ils m'ont dit : "Tu as perdu ton fils, ton père, ta belle-mère et ta femme." Ce mois de novembre, j'ai perdu neuf membres de ma famille. » Ces mots, Daddy Hassan les prononce avec une douleur contenue. Comme lui, des milliers d'autres Sierra-Léonais ont été fauchés par le virus ou ont vu leurs familles décimées.Vaccination préventive : une course contre-la-montre« Ce n'est qu'une question de temps avant que nous enregistrions une nouvelle épidémie d'Ebola », alerte le Dr Desmond Maada Kangbai, chargé de vaccination au sein du ministère de la Santé.Face à cette menace persistante, la Sierra Leone a lancé, le 30 novembre 2024, une campagne de vaccination préventive destinée aux soignants et travailleurs de première ligne. Avec le vaccin Ervebo, administré en une seule dose, les autorités espèrent éviter une répétition de la tragédie de 2014.« Les soignants sont le premier rempart contre Ebola. S'ils ne sont pas protégés, nous risquons de revivre l'enfer d'il y a dix ans », insiste le Dr Kangbai.La campagne, financée par l'Alliance mondiale des vaccins, Gavi, vise à vacciner 20 000 travailleurs de santé et autres acteurs communautaires. Destinée à couvrir les 16 districts du pays, elle bénéficie d'une logistique optimisée : bien qu'exigeant une conservation à -80°C au niveau national, le vaccin peut être stocké entre 2 et 8°C dans les districts, simplifiant ainsi sa distribution.À écouter aussiDix ans après Ebola, la Sierra Leone mise sur la vaccination préventive [1/2]Un hommage aux héros disparus« À Kailahun, j'ai perdu environ 40 de mes collègues », se souvient le Dr James Sylvester Spire, directeur de la surveillance électronique à l'Agence nationale de santé publique, créée après l'épidémie. Cet ancien chef médical régional du district de Kailahun a gardé intact le souvenir des premières heures de l'épidémie.« Lorsque le virus Ebola a commencé à sévir, personne ne voulait aller travailler à Kailahun. L'endroit était extrêmement silencieux ; si on laissait tomber une épingle, on pouvait l'entendre. Tout le monde avait fui les lieux, les gens s'étaient réfugiés dans la brousse ou ailleurs. Moi, j'étais souvent en contact avec les patients, car lors des supervisions, si vous voyez un patient malade, en tant que professionnel de santé, vous devez le soigner. Et c'est ainsi que la plupart des membres du personnel ont été infectés. »Plus loin, à Kenema, troisième plus grande ville de la Sierra-Leone, le docteur Donald Grant se tient devant une grande pierre tombale, sur un terrain poussiéreux. Les noms gravés racontent une tragédie collective : celle des travailleurs de santé tombés au front lors de l'épidémie.« Voici une liste de 40 agents de santé », indique l'ancien responsable médical du district de Kenema, en caressant la pierre du bout des doigts. « Mais ce n'est que pour Kenema. Le bilan national est bien plus lourd. »Sa voix se brise un instant. « Tous, je les connaissais tous. Chaque nom ici représente un collègue, un ami, une perte irréparable. »En 2014, tout commence lorsqu'un individu infecté en Guinée traverse la frontière pour consulter un guérisseur traditionnel en Sierra Leone. La guérisseuse succombe rapidement au virus et ses funérailles, réunissant des centaines de personnes, deviennent un foyer de contagion incontrôlable. À partir de là, la diffusion de la maladie explose.À écouter aussiSierra Leone : reconstruire la santé dix ans après Ebola [2/2]Victoria Yillia : une survivante marquée à jamaisVictoria Yillia est devenue, bien malgré elle, un symbole de la lutte contre Ebola. Elle était le « premier cas confirmé » de la Sierra Leone, diagnostiqué dans le district de Kailahun en 2014.« J'ai attrapé la maladie d'une femme enceinte soignée par la même infirmière qui s'occupait de moi », raconte-t-elle. Transférée à l'hôpital de Kenema, pendant des semaines, Victoria a traversé un véritable calvaire : la fièvre, les douleurs insoutenables et surtout la peur. « Chaque fois qu'on essayait de poser une aiguille pour une perfusion, je saignais abondamment. »Elle a survécu, mais au prix de terribles pertes. « Quand je suis sortie de l'hôpital, mes parents étaient morts. Je ne trouvais que leurs tombes. J'ai perdu environ 21 proches à cause d'Ebola. »Le legs du Dr Sheikh Umar KhanÀ cette époque, la riposte contre Ebola est dirigée par le Dr Sheikh Umar Khan, expert en fièvres hémorragiques et seul virologue du pays.Écartant le diagnostic de la fièvre de Lassa, le Dr Khan met en place des protocoles stricts pour tenter de contenir la maladie. Mais la pression sur le personnel est immense. Beaucoup tombent malades, lui y compris.Le 29 juin 2014, le Dr Khan succombe au virus, laissant un pays en deuil.« C'était comme perdre un général en pleine bataille, se remémore le Dr Donald Grant. Tout le monde était désemparé, pensant que la guerre était déjà perdue. »Une résilience fragileDix ans après, les échos de la tragédie d'Ebola résonnent toujours dans les esprits. Si des progrès ont été réalisés, comme l'établissement de l'Agence nationale de santé publique et la modernisation des infrastructures sanitaires, beaucoup restent à faire.« L'assainissement reste un problème. Les choses les plus basiques n'ont pas encore été réglées. Avoir de l'eau courante relève encore du rêve pour beaucoup. Si vous ne vous attaquez pas à l'assainissement, les maladies comme Ebola continueront d'émerger », avertit le journaliste Umaru Fofana.Pourtant, l'espoir persiste. « Le Dr Khan m'a enseigné à toujours servir l'humanité, quelles que soient les circonstances, conclut le Dr Grant. Nous devons transmettre cette ardeur aux générations futures pour qu'elles poursuivent ce combat. »À écouter aussiEbola : le virus est-il encore une menace ?Ce reportage a été réalisé avec le concours de l'Alliance mondiale des vaccins, Gavi, financée par la fondation Bill and Melinda Gates.
TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Measles in Brooklyn NY (ABC) Measles in Washington DC (DC Health) Global childhood immunization stalls (WHO) Licensed H5N1 vaccines protect against circulating strains (Nat Med) Viruses moving without passports (European CDC) OC42-SARS-CoV-2 replacement spike virus (PNAS) Deep mutational scanning of Lassa virus glycoprotein (Immunity) Letters read on TWiV 1133 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Elemental sulfur found on Mars Kathy – Lennette Lectures at ASV, including Gail Wertz, ASV 2024 Rich – Electricity maps (Opinions: Nuclear Waste Is Misunderstood; Should We Be Worried About Nuclear Waste?) Alan – Nature sent an investigative reporter to a predatory conference Vincent – Coal-filled trains are likely sending people to the hospital Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Le virus à l'origine de la fièvre de Lassa est transmis à l'homme par contact avec de l'urine ou des excréments de rongeurs. Après une période d'incubation de 2 à 21 jours, le patient contaminé peut développer de la fièvre, des céphalées, des nausées ou encore des douleurs abdominales et des saignements. Quelles sont les régions les plus concernées par la fièvre de Lassa ? Comment éviter la contamination en étant résidant de ces régions ? Dr Marie JASPARD, Infectiologue au service des maladies infectieuses à l'hôpital Saint-Antoine APHP à Paris, chercheur pour l'INSERM, en collaboration avec ALIMA.Retrouvez l'émission dans son intégralité iciLa fièvre de Lassa
Le virus à l'origine de la fièvre de Lassa est transmis à l'homme par contact avec de l'urine ou des excréments de rongeurs. Après une période d'incubation de 2 à 21 jours, le patient contaminé peut développer de la fièvre, des céphalées, des nausées ou encore des douleurs abdominales et des saignements. Le diagnostic est uniquement possible grâce à des tests en laboratoire, ce qui rend le dépistage difficile. Le traitement de la maladie repose sur un antiviral dont l'efficacité est actuellement discutée. Quelles sont les chaînes de transmission de la maladie ? Quels sont les symptômes de la fièvre de lassa ? Comment prévenir la maladie ? Dr Marie Jaspard, Infectiologue au service des Maladies infectieuses à l'Hôpital Saint-Antoine APHP à Paris, chercheur pour l'INSERM, en collaboration avec ALIMA. Dr Ousmane Abdoulaye, médecin généraliste et adjoint coordinateur médical d'Alima sur la mission Nigeria.Programmation musicale :► Ysé – Perdre la tête► Master DJI – Sispann.
Le virus à l'origine de la fièvre de Lassa est transmis à l'homme par contact avec de l'urine ou des excréments de rongeurs. Après une période d'incubation de 2 à 21 jours, le patient contaminé peut développer de la fièvre, des céphalées, des nausées ou encore des douleurs abdominales et des saignements. Le diagnostic est uniquement possible grâce à des tests en laboratoire, ce qui rend le dépistage difficile. Le traitement de la maladie repose sur un antiviral dont l'efficacité est actuellement discutée. Quelles sont les chaînes de transmission de la maladie ? Quels sont les symptômes de la fièvre de lassa ? Comment prévenir la maladie ? Dr Marie Jaspard, Infectiologue au service des Maladies infectieuses à l'Hôpital Saint-Antoine APHP à Paris, chercheur pour l'INSERM, en collaboration avec ALIMA. Dr Ousmane Abdoulaye, médecin généraliste et adjoint coordinateur médical d'Alima sur la mission Nigeria.Programmation musicale :► Ysé – Perdre la tête► Master DJI – Sispann.
In tis episode Dr's J and Santhosh continue their exploration of disease histories, this time with a focus on Lassa fever. Along the way, they cover bollywood lyrics, yogurt drinks, preserved human brains, arena viruses, the roman empire, eponymous disease and their consequences, edible disease vectors, hemorrhagic flu season, disease symptoms and pathology, swollen baby syndrome, natural immunity, global warming and more! So sit back and relax as we gush about hemorrhagic fever!Further Readinghttps://articles.nigeriahealthwatch.com/how-lassa-went-from-a-small-nigerian-town-to-a-well-known-virus/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC286250/#:~:text=Lassa%20fever%20is%20a%20viral,tens%20of%20thousands%20of%20deaths.https://www.science.org/content/article/deadly-viral-illness-exploding-west-africa-researchers-are-scrambling-figure-out-whySupport Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comX/Twitter: @doctorjcomedy @toshyfroTiktok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTFacebook: facebook.com/travelmedicinepodcastPatreon: https://www.patreon.com/travelmedicinepodcast Supporting us monthly has all sorts of perks! You get ad free episodes, bonus musical parody, behind the scenes conversations not available to regular folks and more!! Your support helps us to pay for more guest interviews, better equipment, and behind the scenes people who know what they are doing! https://plus.acast.com/s/travelmedicinepodcast. Hosted on Acast. See acast.com/privacy for more information.
In Guinea bricht 2014 das Ebolafieber aus. Die Epidemie verbreitet sich über mehrere westafrikanische Länder und gilt als größte seit Entdeckung des Ebolavirus 1976. Von Martina Meißner.
TWiV reviews resurgence of Lassa fever in West Africa, at least 3 paralytic cases of cVDPV2 in Zimbabwe, CWD from eating prion-laden plants, measles in New Orleans and Broward County Florida, failure of Florida Surgeon General to support vaccination, a measles variant in Switzerland, SARS-CoV-2 persistent infections, leaky blood-brain-barrier for long COVID brain fog, West Nile virus transmitted among mosquitoes by the excreta, and viroid-like colonists of human microbiomes. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Resurgence of Lassa fever (Science) cVDPV2 in Zimbabwe (UNICEF) CWD from eating plants (CIDRAP) Measles in New Orleans (LA Dept Health) SARS-CoV-2 persistent infections (Nature) Leaky BBB for brain fog of long COVID (Nat Neurosci) Measles in Broward County FL (7 News) Failure of FL Surgeon General to support vaccination (X) Measles variant (Eurosurveillance) West Nile virus transmitted among mosquitos by excreta (bioRxiv) Mosquito life cycle (YouTube) Viroid-like colonists of human microbiomes (bioRxiv) Letters read on TWiV 1091 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Sustainable energy in America 2024 factbook Kathy – Life Magnified USPS stamps Rich – “How plants communicate with each other when in danger” by Kasha Patel (Original Nature Communications article) Alan – A Sargasso Sea of Space card game. Vincent – Tell Me When It's Over by Paul Offit Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
TWiV reviews a fatal Alaskapox case, MERS in Kenya, diagnostic tests for Nipah and Lassa diseases, HPV vaccination rates in the US, cases of measles in Arizona and Minnesota, hepatitis C virus-derived RNA circles in infected cells, and prevention of respiratory virus transmission by resident memory CD8+ T cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Fatal case of Alaskapox (AK Beacon) MERS in Kenya (Emerg Inf Dis) Diagnostic tests for Nipah and Lassa (CEPI) Measles in Arizona and Minnesota HCV-derived circular RNAs (PNAS) Resident memory CD8 T cells prevent respiratory virus transmission (Nature) Letters read on TWiV 1087 1:24:33 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Visualizing Science: Illustration and Beyond Brianne – Vaccination from the Misinformation Virus and Invisible Corps Alan – Preventing needlephobia in kids Vincent – Two new Djs I discovered Rosana Nun and Sunset Cartel Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
Dr. Mireille Kamariza is an Assistant Professor in the Department of Bioengineering at UCLA and co-founder and CEO of OliLux Biosciences, a company dedicated to providing low- cost, portable and reliable diagnostic devices in low-resource settings. She is a chemical biologist with expertise building diagnostics tools against infectious organisms. With a background in chemical biology and infectious disease research, she researches new tools to selectively probe molecular activity of live cells, in real-time, with versatile applications in research and medicine. She was previously a Junior Fellow at the Harvard Society of Fellows working with Prof. Pardis Sabeti at the Broad Institute of Harvard and MIT. There, she worked on developing CRISPR-Cas13 assays to detect bloodborne viruses such as Ebolavirus, Lassa virus, Yellow Fever virus, and many others. Prior to her appointment at Harvard, she completed her doctoral studies in Biology at Stanford University where she developed a new diagnostic technology for the rapid and simple detection of tuberculosis at the point-of-care. This project was awarded a Bill & Melinda Gates Foundation grant to test their diagnostic devices in places with high levels of disease. In addition, her work was translated into what is now OliLux Biosciences. Dr. Kamariza has received numerous awards, including being named as one of Chemical & Engineering News's Talented 12 in 2020 and Endpt's 20 under 40 in 2023. In December 2022, Nature Medicine named Dr. Kamariza as one of 11 early-career researchers to watch. --- Support this podcast: https://podcasters.spotify.com/pod/show/theia-hc/support
HEDEP, Kılıçdaroğlu ile Özdağ arasında imzalanan protokolü "utanç belgesi" olarak nitelendirirken, işbirliğine engel olmayacağını vurguladı. Yunanistan, Türk vatandaşlarına Ege adalarında kapıda vize imkanı tanıyacaklarını söyledi. Bu bölüm Lassa hakkında reklam içermektedir. “Yaya Geçitlerinde Sağlam Duruyoruz, Hayatı Koruyoruz!” kampanyasını buradan izleyebilirsiniz. #SağlamsaLassa
TWiV reviews a Lassa virus mRNA vaccine that confers protection against disease without inducing neutralizing antibodies, and a CRISPR-based method for engineering the genome of RNA viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Virologist Bob Lamb dies (Northwestern Now) Lassa virus mRNA vaccine (Nat Commun) CRISPR engineering of RNA viruses (Sci Adv) Letters read on TWiV 1045 Timestamps by Jolene. Thanks! Weekly Picks Angela – More than 5,000 new species discovered in Pacific deep-sea mining hotspot (journal article) Brianne – The story of our universe may be starting to unravel Rich – Sunlight Changes Unequally All Year Long Alan – Arm swing asymmetry in overground walking Vincent – The Farm at the Javits Center Listener Pick Asal – Ig Nobel Prizes honor zombie spiders, rock-licking scientists, and a clever commode Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
When Ebola virus was first spotted in west Africa at the end of 2013, few people were ready. The region had no developed or systematic health system, patients were scattered across remote rural areas, and other infections, such as malaria, were common and mimicked the early symptoms.But a team in remote Kenema, in Sierra Leone, had been working to fight a different virus – Lassa Fever. They had set up a clinic with diagnostic testing and communications with the outside world. A team of experts had been trained in how to detect and diagnose viral hemorrhagic fevers. They may not have been expecting Ebola, but they had the expertise and some of the equipment and infrastructure needed to help people understand what was happening as the deadly and frightening virus started to spread across borders.Dr. Robert Garry, who specializes in viruses, had helped set up the team studying Lassa in west Africa. He helped the world understand what was going on with Ebola and quickly understood that his team's preparations in Kenema had helped in the fight to track and control the virus.Such preparations also helped when COVID-19 started spreading around the world in 2020.In this episode of One World, One Health, listen as Dr. Garry explains how he got interested in studying viruses and how preparedness matters in fighting global threats.
What if you could explore the world of One Health in Nigeria and learn from top scientists, like Dr. Nathan Shehu, Dr. Pam Luka, and Dr. Loya Inka Asala? In this fascinating episode, we dive into the West African Center for Emerging Infection Diseases program, and its goal to rebuild expertise on arboviruses, collect and identify mosquitoes, and assay them for potential virus-carrying. Join us as we discuss the power of cross-training and the importance of approaching global health with humility.We also take a closer look at the passion and achievements of our guests' medical careers. Dr. Shehu shares his journey to his current research on Lassa fever, while Dr. Pam Luka talks about his childhood at his father's veterinary clinic at the MVRI campus and his journey as a sales rep. Discover how these experiences have shaped their paths and the importance of recognizing different levels of staff in healthcare and research. Don't miss our exploration of understanding and managing Lassa fever, the challenges of saving patients with Lassa fever, and the importance of early diagnosis and compassionate care.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don't forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don't hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Twitter @Infectious_SciInstagram @tick_virusFacebook Infectious Science PodcastSee you next time for a new episode!
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Dr. Miles Carroll, the professor of emerging viruses at the Pandemic Sciences Institute at Oxford University in the United Kingdom, and Sarah Gregory discuss the influence of landscape patterns on exposure to Lassa fever virus in Guinea.
In this episode, we catch up cheese monger extraordinaire Lassa Skinner about the many hair pin turns she has taken in her storied career as a cheese professional. Lassa is co-founder of Culture magazine, author of two books; 'Cheese for Dummies' and 'Cheese Boards to Share', and also is the mind behind Counter Culture events to help further cheesesmongers' education.Heritage Radio Network is a listener supported nonprofit podcast network. Support Cutting the Curd by becoming a member!Cutting the Curd is Powered by Simplecast.
The question of the SARS-CoV-2 origin: whether it was a zoonotic spillover from a wet market, or an engineered virus that escaped from the Wuhan Institute of Virology, is seemingly a debate that will never go away. Most interestingly, while scientists with specific domain expertise seem to be building a consensus towards the former, public opinion appears to be trending towards the latter. This delta between expert and popular opinion has been helped along by the frothy discourse in mainstream and social media, with most figures that we cover in this podcast dead-set certain that it came from a lab. Most recently, Sam Harris hosted on his Making Sense podcast the molecular biologist Alina Chan and. science writer Matt Ridley, spokespersons for the lab leak case, and authors of "Viral: The Search for the Origin of COVID-19". To a layperson, and certainly to Sam, they put forward a rather watertight case. Intrinsic to the arguments advanced were the ideas that (a) experts in the area were refusing to engage with and unable to answer their arguments, and (b) a strong implication that there is a conspiracy of silence among virologists not just in China but internationally, to suppress the lab leak hypothesis.So, as a case study in the public understanding of science, it seems like a pretty pickle indeed. To help unravel the pickle(?) in this somewhat special episode, we are joined by three virologists who are amply qualified to address the topic; both in terms of the evidence and whether they are involved in a conspiracy of silence.Kristian Andersen is a Professor in the Department of Immunology and Microbiology at Scripps Research. He focuses on the relationship between host and pathogen, using sequencing, fieldwork, experimentation, and computational biology methods. He has spearheaded large international collaborations investigating the emergence, spread and evolution of deadly pathogens, including SARS-CoV-2, Zika virus, Ebola virus, West Nile virus, and Lassa virus.Prof Michael Worobey, is the head of the department of Ecology and Evolutionary Biology at the University of Arizona. His work focuses on the genomes of viruses, using molecular and computational biology, to understand the origins, emergence and control of pandemics. Recently, his interdisciplinary work on SARS-CoV-2 has shed light on how and when the virus originated and ignited the COVID-19 pandemic in China and how SARS-CoV-2 emerged and took hold in North America and Europe.Prof Edward "Eddie" Holmes, is an NHMRC Leadership Fellow & Professor of Virology at the Faculty of Medicine and Health at Sydney University, a member of the Sydney Institute for Infectious Diseases, a Fellow of the Australian Academy of Science and a Fellow of The Royal Society. He is known for his work on the evolution and emergence of infectious diseases, particularly the mechanisms by which RNA viruses jump species boundaries to emerge in humans and other animals. He has studied the emergence and spread of such pathogens as SARS-CoV-2, influenza virus, dengue virus, HIV, hepatitis C virus, myxoma virus, RHDV and Yersinia pestis.All three researchers have specialist expertise and decades of experience directly applicable to tracking viruses and their adaption to humans, and, fair to say, are fairly eminent in their fields (Eddie in particular!). Further, they are among the relatively small set of researchers collecting and analysing primary evidence on the origins of SARS-CoV-2, communicating their findings in top-ranked journals, including Nature and Science. In this episode, Chris and Matt put to this trio of Professors the claims rasied by lab leak advocates to see what these (damn conspirators) experts have to say for themselves.LinksSam Harris Making Sense
Sarah Gilbert is the Said Professor of Vaccinology at the University of Oxford. She works on vaccines for many different emerging pathogens, including influenza, Nipah, MERS, Lassa, Crimean-Congo haemorrhagic fever, and in 2020, she initiated the SARS-CoV-2 vaccine project. Working with Oxford colleagues she is able to take novel vaccines from design to clinical development, with a particular interest in the rapid transfer of vaccines into manufacturing and first in human trials. She is the Oxford Project Leader for ChAdOx1 nCoV-19, a vaccine against the novel coronavirus, SARS-CoV-2 which is now in use in many countries around the world. Read more in her book Vaxxers: A Pioneering Movement in Scientific History
On episode #13 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 9/29/22 – 10/12/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Efficacy and safety of switching to Dolutegravir/Lamivudine versus continuing Tenofovir Alafenamide (CID) Antibiotic combinations reduce Staphylococcus aureus clearance (Nature) Cholera Vaccine: Recommendations of the advisory committee on immunization practices (CDC) Detection of Treponema pallidum DNA during early syphilis stages (CID) Association between toxoplasmosis and bipolar disorder (Journal of Psychiatry) The efficacy of soap against schistosome cercariae (PLOS NTD) Recurrent ESBL Escherichia coli urosepsis in a pediatric renal transplant patient (NIH) After action review of the response to an outbreak of Lassa fever in Sierra Leone (PLOS NTD) Music is by Ronald Jenkees
Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Tom Monath Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Fever by John Fuller (Amazon) Crozet BioPharma Timestamps by Jolene. Thanks! Weekly Picks Dickson – Jazz – Small Group #3: Dave Brubeck Quartet. Dave Brubeck, Piano; Joe Morello, Drums, Paul Desmond, Alto Saxophone, Eugene Wright, Bass: Signature Album: Time Out. Signature Song: Take Five. Rich – Wilderness Safaris (wiki) Alan – Madhouse at the End of the Earth, by Julian Sancton Vincent – Raymond Chandler and his protagonist Philip Marlowe. Listener Picks Philip – Students bitten by bats inside college residence hall Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv
Today on TruNews, If you think the Needle Nazis have retreated, you need to think again. Their needles are retreating, but not their evil schemes to infect humanity with their devilish pharmakeia vaccines. The Needle Nazis encountered strong resistance to their scheme to vaccinate the entire human population with Covid 19 vaccines. Too many people became aware that the substances were not vaccines, but instead, were mRNA gene therapy drugs. The news media called it vaccine hesitancy. I call it wisdom. How will the Needle Nazis overcome gene therapy vaccine resistance? The next time the Pharmaceutical Nazis may not need their needles. They may give you the vaccine through the air. National Geographic recently reported that scientists are working on contagious vaccines. You heard me correctly. I did not say vaccines to stop contagious diseases. Instead, they are developing vaccines that are contagious. In other words, your brother-in-law who watches CNN and still wears a mask while driving in his car alone will readily get vaccinated and become contagious. He will come to your house and infect you with the vaccine, not the virus. You will have to avoid vaccinated people to avoid being vaccinated. The National Geographic magazine said: Imagine a cure that's as contagious as the disease it fights—a vaccine that could replicate in a host's body and spread to others nearby, quickly and easily protecting a whole population from microbial attacks. That's the goal of several teams around the world who are reviving controversial research to develop self-spreading vaccines.Researchers are currently developing self-spreading vaccines for Ebola, bovine tuberculosis, and Lassa fever, a viral disease spread by rats that cause upward of 300,000 infections annually in parts of West Africa. The approach could be expanded to target other zoonotic diseases, including rabies, West Nile virus, Lyme disease, and the plague.My friend, only the blood of Jesus Christ can protect us from such madness in the last days. I will fight the Needle Nazis for as long as I live. The Davos crowd calls it the Great Reset. They are resetting the world. My Bible says there's an even greater reset coming that will reset the cosmos. I call it the Greatest Reset.With financial support from many of you, we produced a movie called The Greatest Reset. Episode One is the Beast Rising. I am pleased to tell you that the film is finished. It is currently under legal review by a prestigious law firm. When the lawyers sign off on the movie in the coming weeks or sooner, we will release the film immediately.Matt Skow is the director and he's here today to talk about the film and show us some video clips from the documentary. Rick Wiles, Matt Skow. Airdate 4/8/22https://www.greatestresetmovie.com/