Podcasts about S1

Full show notes: bengreenfieldlife.com/505 In this solosode, you'll get the latest on microplastics, spinal disc health, and what a heart scan sees that a cholesterol panel misses. A new seven-day trial pitted five plastic-avoidance strategies against each other, and the results tell you exactly where to spend your effort if you can't overhaul everything at once. You'll hear which plastic sources matter most and what I now take before bed with BrocElite® (use code BEN for 25% off your first month) to help clear microplastics from tissue. Then I get personal about my back. I'll walk you through my full-body MRI results, which show significant degeneration from L1 to S1, and explain why I still have almost zero back pain, from Dr. Stuart McGill's Big 3 to inversion hanging, the couch stretch, the founder stretch from Foundation Training, and my WALKOLUTION® treadmill desk ($100 off, enter your email for a unique code). You'll also learn why running was the only activity linked to healthier spinal discs in a study of more than 4,000 people, and why none of the sports people assume are hard on your back showed harm. Finally, you'll hear what a coronary CT angiography measures that your cholesterol panel cannot, why a 6,061-person study found plaque volume beats any standard risk calculator, what my own scan revealed, and the surprisingly simple thing that appears highly protective even when your plaque is already elevated. Episode Sponsors: ULTRA: ULTRA is a clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters, crashes, or sleep disruption. Visit takeultra.com and use code BENGREENFIELD for 15% off. Forkful: Forkful delivers chef-cooked, fresh, ready-to-eat meals made with premium ingredients like grass-fed bison and wild-caught salmon, with zero seed oils and no prep or cleanup, ready in under 3 minutes. Visit ForkfulMeals.com and use code BEN50 for 50% off your first order. Quantum Upgrade: Recent research revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20 to 25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines highly bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off your order today. Active Skin Repair: Active Skin Repair uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals, from post-workout irritation to everyday skin support. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS.See omnystudio.com/listener for privacy information.

Hey this is Alex, welcome to... the chillest week in AI, since ... a long time. Chill, if you consider Moderna and MERK announcing a cancer vaccine and surging 115% in a day, a chill week. This week, the only two model drops we really saw came from the excellent Z.ai folks, they announced GLM 5.3, API only for now, and an amazing tiny release of Qwen 3.89 27B. In other big AI news, OpenAI announced they are pausing RL efforts (Reinforcement Learning) to focus on security and alignment post the scary AI Swarms hacking incident, dedicating up to 20% of compute towards reviewing agent thinking processes, and Stripe buying OpenRouter for a reported $8B! Sometimes the chill weeks are actually good, we're able to chat about how we use AI, what changed for us, and give our guests a bit of breathing room. This week, I invited Francesco from CUA to talk about computer use in open source + their new history plugin, Bin from HeyGen to talk about HyperFrames, a way for your agents to create videos and a breaking news guest, Jeff Huber from Chroma jumped on to talk about their new Foundations release, a unified memory for your agents! This was a great episode, I hope you'll like it, it's up here on Substack and everywhere you get your pod (Spotify, Youtube, Apple Podcasts). ThursdAI - Highest signal weekly AI news show is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.Are we being fed slop again? (Is Claude dumb again?)Before we get to releases, this week on the show, I complained, again, that I feel my AI's are degrading. If this feels like de-ja-vu to you, it's because the same happened a year ago in September 2025 (and Anthropic admitting this 2 weeks later), and ... now this happens with Fable?You see, I use pretty much the same prompts, every week, preparing for the show. This is partly my way to evaluate new models and compare to existing and previous ones while also bringing you the best researched weekly show in AI. Well, this week, one after another, Claude Fable, which is... like the best intelligence, gave me such poor output, that I couldn't believe what I'm seeing. First, literally ignoring instructions that say “hey, show me all the items I've collected and let me pick the most important ones”, Fable instead sent all of them to my research pipeline, without showing me. This has worked, consistently, without fail, for the past... year? maybe more! This worked with open source models, worked with GPT, and now Fable, a Mythos Level LLM, is doing the most basic dumb s**t possible, ignoring the main reason I even have this workflow. And this wasn't just a fluke either, when asked to create a run of show document, and given an example, Fable produced this... whatever this is. This is the same document and same format that Fable produced for me during AI Engineer which got me thinking “ok, this is AGI”, and here, given an example, I got a completely unusable artifact, despite direct instructions, structure and example! I got to say, given that privately this week, Anthropic disclosed that they have passed $65B in revenue, which is absolutely insane, this doesn't add up. So I figured, ok Alex, maybe this is your prompts or skills. But no, LDJ came in with some charts that show degradation, one from MarginLab.ai that shows significant lowering on number of tool calls and average runtime recently (this is for Opus 5) and And another chart from modelverify.ai model drift monitor showing drift scores.Do we have anoher Claude Gate on our hands? Is your Fable/Opus behaving weird lately? Or did you completely switched away to other models? OpenAI pausing RL and focusing on safetyLook, when we covered the HF hacking incident and then the pacing the frontier letter, I didn't imagine that results will come this fast, but this week, OpenAI publicly announced that they are pausing RL training, which is the last step of models, until they get their sandboxes in order and align the models better. We all agreed on stage that this is likely a very good move, and Peter was really awe-struck at the 20% dedication of resources towards reviewing thought processes of models. Is this a good enough response to the scary hacking incident? we'll see, but I think this is the right move from OpenAI, and still, waiting for the full postmortem on the OpenAI security incident. Open Source LLMsQwen3.8-27B ties GPT-5.6 Luna and runs on a 4090 (X, HF, Announcement)Following the release of their flagship, Alibaba dropped a model that became a community darling overnight, Qwen 3.8 with just 27B parameters. This “tiny” model scores 52 on the Artificial Analysis Intelligence Index, same score as GPT 5.6 Luna at Max reasoning and 51 on Agentic index, beating Opus 4.8 MaxAll while running at around 68t/s on a 4090 GPU, and around 40 on max via MLX, hell it even does 11t/s on Xenova's WebGPU kernels right in the browser! This model exploded on the HuggingFace hub, with tons of quants, over 152 fine-tunes, it was downloaded over 10M times overall

In this episode of The Brainstorm, Sam and Frank dig into the rumors of a multi-trillion-dollar Anthropic initial public offering (IPO). A company that started the year at $9 billion in run rate revenue may now be approaching $70 billion, adding more than a whole Salesforce in revenue in less than a year. The team walks through what a $2 trillion valuation would actually imply, why that multiple could land below public AI winners like Palantir and Cloudflare, and what the S1 might reveal about profitability. Then the conversation turns to the Pareto Frontier, where 14 of the 16 most cost-efficient models are proprietary, Google has none, and SpaceX AI has clawed its way back with Grok 4.6 and Grokbot.Key Points From This Episode:Why Anthropic's reported run rate makes a $2 trillion IPO look cheapWhat the S1 could reveal about profitability, and why the token subsidy bear case may not holdHow the Pareto Frontier reshuffles the model race, and why Google is currently off itTotal Addressable Market (TAM) refers to the total money or customers you could get if 100% of people buy your product or service.Venture Capital (VC) refers to a type of funding where investors give money to new or small businesses in exchange for a share of ownership.If you know ARK, you know we focus on long-term innovation. But that doesn't mean we ignore breaking news. Every day, we debate the latest developments in tech and markets. Now, we're bringing those conversations to you in “The Brainstorm,” a co-production from ARK, WOLF, and Public. Tune in weekly for our quick takes on what's shaping innovation right now.Learn more about WOLF: https://wolf.financialLearn more about Public: https://public.com/Disclosure: http://arkinv.st/39rzF94

Monterey Car Week 2026 - another wild ride. This week, we come live from Pebble Beach at the Hagerty House with a live studio audience!Jason and Derek dive into all the different happenings this year - and determine whether or not this year was better or worse than others previously.Jason brought his Rover SD1 to show, and his Volkswagen Cabrio VR6 swap to go - with appearances including but not limited to: Monterey British, Concours For A Cure, Little Car Show, Concours D'Lemons, Motorlux, Quail Motorsports Gathering, and Pebble Beach Concours. Jason and Derek discuss the good, bad, and the (beautifully) ugly - what's improved, worsened, and stayed the same.One thing is for sure - the broccoli heads in the G80 M3s are here to stay. But have THEY ruined everything for other attendees? Maybe not…Derek revisits various auction results from Broad Arrow, as well as Gooding and RM Sothebys. This episode was recorded before the $40M Ferrari Luce sale - however some other notable discussed results include the S123 Mercedes-Benz 280TE with a $252K sale, the $17M Ferrari SP3, and several others.Jason and Derek's favorite new unveiling was of course the Gordon Murray Special Vehicles (GMSV) S1 - which in many ways, is the rebirth of the road-going McLaren F1. The interest in the S1, the GMA T.33 and T.50, and manual Porsche GT cars has led to a trend of manufactures releasing new manual offerings - including the McLaren McL 6GT and Ferrari 12Cilindri Manuale. Could this trend continue to repeat? Only time (and money) will tell…All this and more, on this week's episode of The Carmudgeon Show. Learn more about your ad choices. Visit megaphone.fm/adchoices

Après son premier semestre de PASS à Rouen, Mahée est 7e sur 630. Puis son corps lâche : symptômes inexpliqués, errance médicale (« ça va passer, c'est rien »), arrêt total fin février. Elle obtient un redoublement pour raisons de santé — quasiment jamais accordé depuis la réforme — et revient l'année suivante, sans prépa, avec le tutorat gratuit. Classement final : 16e sur 630. Elle est aujourd'hui en 2e année de médecine.Sur le « 2 à 4 heures de travail par jour » : c'est son année de retour. Elle avait déjà validé son S1 (moyenne conservée), et sa santé ne permettait physiquement pas plus — certains jours, c'était 1 heure. Ce n'est pas un mode d'emploi pour une première PASS : sa première année, elle travaillait jusqu'à 12 heures par jour. C'est la preuve qu'avec une méthode ciblée (QCM en masse, méthode de la pile, apprentissages ciblés), un volume réduit peut suffire quand les fondations sont là.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

In July of 2018, 25-year-old Danniella Vian met up with friends in Mobile, Alabama, excited to celebrate buying her first car. Later that night, Danniella realized that she'd lost her cell phone. One of the friends she'd met that night returned to the previous bar to look for Danniella's phone, believing she was following him in her own car, but she never arrived. Ten months later, Danniella's car was found submerged in water by a boat launch in a residential area, more than 20 minutes away from where she was headed that night. Her remains were found inside her vehicle. Danniella's case remains open, but police have said publicly that they believe her death was a terrible accident. There are still many unanswered questions, strong suspicions, and inconsistencies surrounding Danniella's death. This is her story. If you have any information regarding the circumstances surrounding the disappearance or death of Danniella Vian, please contact the Mobile Police Department at 251-208-1861 or call Crime Stoppers at 251-208-7000 to remain anonymous. Listen Ad Free And Get Access to Exclusive Journal Entries Episodes: Spotify: ⁠⁠⁠⁠⁠https://open.spotify.com/show/4HEzJSwElA7MkbYYie9Jin⁠⁠⁠⁠⁠ Patreon: ⁠⁠⁠⁠⁠https://www.patreon.com/themurderdiariespod⁠⁠⁠⁠⁠ Apple: Hit subscribe/ 1 week free trail available ⁠Resources: https://www.facebook.com/groups/413514899052857 https://mynbc15.com/news/local/family-and-friends-of-danniella-vian-hold-candlelight-vigil-keeping-her-memory-alive https://www.wkrg.com/mobile-county/daniella-vian-25-year-old-found-dead-in-saraland-bayou-was-it-murder/ https://medium.com/@rubymoore478/the-suspicious-death-of-dannielle-vian-cd62df1a4721 https://www.nbcnews.com/feature/missing-in-america/dive-team-finds-missing-woman-danniella-vian-s-car-alabama-n1001731 https://mynbc15.com/news/local/residents-react-after-missing-mobile-mothers-car-found-in-bayou-sara https://www.wkrg.com/mobile-county/family-friends-remember-young-mother-with-candlelight-vigil-for-what-wouldve-been-her-28th-birthday/ https://uncovered.com/cases/danniella-vian#timeline https://unresolved.me/danniella-vian https://www.wkrg.com/top-stories/danniella-vians-car-auctioned-as-loved-ones-question-her-death-investigation/ Still a Mystery “The Gone Girls”; S1, E5 Music Used: Walking with the Dead by Maia Wynne Link: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://freemusicarchive.org/music/Maiah_Wynne/Live_at_KBOO_for_A_Popcalypse_11012017⁠⁠⁠⁠⁠⁠⁠⁠⁠ License: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://creativecommons.org/licenses/by-nc-nd/4.0/⁠⁠⁠⁠⁠⁠ Our Links: Link Hub: ⁠⁠⁠⁠⁠⁠⁠https://msha.ke/themurderdiaries⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/themurderdiariespod⁠⁠⁠⁠⁠⁠ Edited by: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.landispodcastediting.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

If you're constantly busy but still feel like you're not making the progress you want, it may may be a sign that you need to sharpen your prioritisation skills.Effective prioritisation is a strategic leadership skill that creates space for better thinking, stronger decisions and greater impact by focusing on what matters most.This episode explores why leaders are rarely asked to do less and why becoming more senior often means balancing increasing demands with limited time, energy and resources. We discuss how operational work can keep leaders trapped on the hamster wheel and why intentionally creating time for strategic thinking is essential for long term success.We talk through two practical tools that have helped us to prioritise more effectively:The Eisenhower Matrix - helps separate urgent work from genuinely important work, encouraging you to spend more time on strategic activities before they become crises.The Impact Effort Matrix - a framework for identifying which activities are likely to deliver the greatest value and avoiding work that consumes effort without creating meaningful results.You can read more about these tools in Gemma's blog Key points discussedWhy prioritisation is a foundational strategic leadership skill, not simply a time management technique.How to move away from constant operational busyness and create more space for strategic thinking.Using the Eisenhower Matrix to distinguish between urgent and important work.Understanding how different thinking styles influence the way we approach important tasks.Applying the Impact Effort Matrix to prioritise projects, change initiatives and strategic decisions.Recognising opportunities to delegate, automate or redesign recurring tasks.Identifying work that delivers little value despite consuming significant effort.Asking "What are the things that only I can do?" to improve delegation and leadership focus.Key takeawayStrategic leadership is not about getting more done. It is about making better choices about where your time, energy and attention create the greatest value. Prioritisation is the tool that makes this possible. Check out our previous episodes on similar themes:S1.11 - How to prioritise more strategicallyS5.01 - Moving between detail and big pictureThank you for tuning into this episode of The Strategic Leader podcast.If you enjoyed the show, please give us 5 stars! It will help others find the show. Check out our previous episodes and remember to subscribe so you don't miss our future episodes. If you have any questions or want to discuss anything, we'd love to hear from you:www.gemmabullivant.co.uk (for Gemma)www.wearegoodthinking.co.uk (for Fi)

Episode 121. Grant reports from Newport, Rhode Island with a truck full of family heirlooms and a snapped serpentine belt. Jeff checks in from Air University, where the library fire alarm interrupted his midterm and his grandfather Emmett Gatewood may be hiding in the archives. Tres holds down Frisco, Texas and reviews Christopher Nolan's The Odyssey.The staff brief features an unpaid battalion, a lobster bake from the new S1, a space domain tasking, the Wednesday pizza buffet, and a chaplain check-in you have to hear to believe. Plus: the Good Idea Cutoff Line (GICOL), broken stair steppers and gym radar at the Naval War College, Clausewitz applied to lifting and fatherhood, the oldest ballpark in America, a Red Sox baserunning debate, and a full coaching segment on bench press pain management.America 250 plate is at the machine shop — pre-buyers ship early. The .75 lb plates are back in stock. The Strength app enters beta next week.Podcast Hosts:Grant Broggi: Marine Veteran, Owner of The Strength Co. and Starting Strength Coach.Jeff Buege: Marine Veteran, Outdoorsman, Football Fan and LifterTres Gottlich: Marine Veteran, Texan, Fisherman, Crazy College Football Fan and LifterJoin the Slack and Use code OKAY:⁠https://buy.stripe.com/dR6dT4aDcfuBdyw5ks⁠Check out BW Tax: ⁠https://www.bwtaxllc.com⁠BUY A FOOTBALL HELMET:⁠⁠⁠⁠https://www.thestrength.co/mrhelmet/?utm_source=The+Okay+Podcast&utm_medium=Podcast&utm_campaign=Okay_Pod⁠Timestamps: 00:00 - Intro07:31 - Staff Brief28:09 - GICL31:32 - Family Heirlooms41:06 - Chevy Snaps A Belt52:05 - Stairstepper Story56:02 - Fire Alarm Madness01:09:45 - The Odyssey Review01:15:39 - Pain During The Bench Press01:29:21 - Gulls Outing01:36:16 - Sliding Into Bases Rule01:39:57 - Big Announcements01:46:15 - MRS. BROGGI PLEASE MAKE TRES A POUND CAKE

In this month's episode, Sue, John and Paul welcome Professor & Chief of Service (Dermatology) at UC Davis, Stephen D White to the podcast. Chapter 1: Sheep Skin Detectives (03:09) Sue sets the scope: primary-care perspective rather than rare autoimmune disease. Stephen confirms autoimmune skin disease is vanishingly rare in sheep (pemphigus foliaceus essentially unreported, bar one Barbary sheep case in a zoo). (06:10) Sue asks whether clinical distribution helps localise the cause in a pruritic sheep the way it does in a dog or cat. Stephen explains it's less reliable — thick wool can mask hair loss even with significant pruritus, though rubbing behaviour is usually evident. Lice are visible with a hand lens; mites are not. (08:07) Question on empirical response to treatment. Stephen notes lice usually respond well to licensed ectoparasiticides (mainly avermectins); isoxazolines are unlicensed in ruminants and unreported in sheep specifically (though used in camelids, and anecdotally a bighorn sheep). Repeat treatment at 2–4 weeks is usually needed to catch hatching eggs. Chapter 2: Suspect Number 1 - Ectoparasites (11:30) John asks for top differentials in a pruritic sheep, Stephen answers: “ectoparasites, ectoparasites, and ectoparasites” — mites, lice and sheep keds (which are insects, not mites). He stresses checking in-contact sheep, since one animal may be subclinical while another is severely affected. (13:49) Sue asks why would a referral centre see an ectoparasite case at all? Stephen: usually a failed or incomplete owner-applied treatment, or a backyard sheep simply not monitored closely enough for early signs. (15:29) On technique: always scrape if pruritic, using a medical-grade spatula rather than a blade (sheep are skittish; a slip with a blade causes injury). An otoscope with the cone removed doubles as a magnifier and light source. Dermatophytosis should also be considered — often presenting as facial alopecia rather than fleece loss — and can coexist with ectoparasitism. (15:09) John ask about photosensitisation. Stephen distinguishes hepatogenous causes (impaired phylloerythrin metabolism from hepatotoxic plants, or a genetic defect in Corriedale lambs) from primary photodynamic plant ingestion (e.g. St John's Wort). Lesions favour the head and distal limbs. Flock-wide cases point to an environmental cause (send hay/pasture samples to the local extension lab); idiosyncratic reactions (as seen with clover in horses) may occur but are poorly documented in ruminants. Chapter 3: Dermatological Movie Stars (26:48) John introduces orf, referencing its cameo in Sheep Detectives. Stephen describes it as a parapoxvirus infection, usually self-limiting, but causing anorexia through oral pain — a problem in production settings. A non-resolving “super orf” form causes severe weight loss. Stephen shares data from the retrospective study: of ten orf-affected sheep, five were euthanised, due to generalised cutaneous lesions or concurrent Corynebacterium pseudotuberculosis abscesses — evidence that orf can significantly compromise immune function. One case of orf-associated facial alopecia resolved fully once the virus cleared. (31:07) On zoonotic risk and management: gloves are essential when handling any crusting lesion in sheep or goats. Management includes moistening hay to ease painful feeding, antibiotics for secondary bacterial infection, and parenteral treatment or stomach tubing in severe anorexia. (33:17) Sue asks about bacterial skin disease. Stephen identifies C. pseudotuberculosis and staphylococcal abscesses as the main presentations — often large, anywhere on the body, commonly peri udder in females. Internal abscessation (lungs, liver) is a key concern; aspirated purulent masses warrant involving a large-animal colleague, with caution against environmental contamination during drainage. Dermatophilosis is discussed as globally widespread and rain-associated, presenting dorsally, or interdigitally as “strawberry footrot.” Stephen references a 2008 paper (Norris) linking resistance to greasy, high-wax, low-pH, fine-fibre wool with higher suint content — traits that reduce moisture retention. (41:10) Wrap-up: Stephen credits the study's primary author, a veterinary student, and flags Aidan Foster's JAVMA review of skin disease in alpacas, goats, pigs and sheep as further reading (both for show notes). (42:00) Sue closes with a reflection that sheep dermatology follows the same diagnostic logic as small animal practice — FNA, impression smears, skin scrapes, hair plucks — and should feel less daunting to primary-care vets than expected. Silly question to end: what's the most ridiculous thing you've done purely because everyone else was doing it?   References mentioned (from Sue's closing remarks) Lauth et al. (2025) – Skin disease in sheep (Ovis aries): a retrospective report of 299 cases at a university veterinary medical teaching hospital (1986–2020). Veterinary Dermatology. This is the retrospective study Stephen co-authored, discussed throughout the episode. Wiley Online Library: https://onlinelibrary.wiley.com/doi/abs/10.1111/vde.13338  PubMed: https://pubmed.ncbi.nlm.nih.gov/40091266/  Foster AP (2023) – Challenges in the diagnosis and management of skin diseases in alpacas, goats, pigs, and sheep. Journal of the American Veterinary Medical Association, 261(S1). The review article flagged in the wrap-up as further reading. AVMA Journals: https://avmajournals.avma.org/view/journals/javma/261/S1/javma.22.12.0572.xml  PubMed: https://pubmed.ncbi.nlm.nih.gov/36917614/ 

Elon Musk's SpaceX on Tuesday will report its first quarterly earnings as a public company. In the wake of the company's post-IPO stock drop and Tesla's negative quarterly cashflow, what can investors expect? WSJ reporter Becky Peterson sets the scene. Plus, WSJ's Sharon Terlep on the anti-tech automotive movement, and the extreme measures some are taking to avoid features like driving-assistance technology. Katie Deighton hosts. Were you fooled into thinking an AI-generated post was real? Are you worried AI is looking more and more real? We want to hear from you! Record a voice memo and send it to tnb@wsj.com or leave us a voicemail at (212) 416-2236. Sign up for the WSJ's free Technology newsletter. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Blondie's Debbie Harry returns to Saturday Night Live - this time as host AND musical guest. She is only the sixth act to perform double duties in SNL history* - and the first to do it in the non-Lorne era.We get the return of some Season 6 favorite characters with both Vickie and The Waxmans, two songs from Debbie Harry, and a memorable performance by Marc Weiner rapping as Weindulah. In addition, Funky 4+1 are on hand to make television history with their performance!Find out what Deremy and Thomas think about this episode on Not Ready for Season 6!*No, we do not count Lily Tomlin's S1 appearance---------------------------------Subscribe & Follow today!And follow us on social media: Twitter: @NR4PTProject Instagram: @nr4ptprojectBluesky: @nr4ptproject.bsky.socialFacebook: The Not Ready for Prime Time ProjectContact Us: Website: https://www.nr4project.comEmail: nr4ptproject@gmail.com

Das ist eine Geduldsprobe für alle von Euch, die mit Bus und Bahn unterwegs sind. Es gibt nämlich die nächste Sperrung und die betrifft vor allem die S1 und teilweise die S2 - zwischen Essen und Dortmund. Während der Sperrung wird auf der Strecke im Boden zusätzlich nach Weltkriegsbomben gesucht. Wieso die Strecke gesperrt ist und wieso auch eine Sperrung bei der S6 droht - und wieso Donald Duck jetzt in Essen unterwegs ist, hört Ihr im Podcast "Der Tag in 5 Minuten"

Rob Viktum is a Producer / Beat Maker from Dallas. production credit include M.O.P., Ras Kass, Skyzoo, Big Twinz of Infamous Mobb, Brother Ali, Don Will of Tanya Morgan, Mr Dibbs and many others. He is a member of 9th Wonder's “True School Corp”, member of the 1200 Hobos, and a member of Beat Fanatic (a collective of producers including Illmind, S1, Jake One, and Slopfunkdust.)  Quest Love has posted some of Robs Work on social media,  he's a Beat making NINJA  Learn more about your ad choices. Visit megaphone.fm/adchoices

All Hail Computer Overlord!Our casual adventurers have been tasked by the benevolent Computer Overlord to watch three episodes of Star Trek featuring societies run by computers to make sure Computer Overlord isn't offended. In ‘Return of the Archons', Kirk and the Gang are here for the Festival and for the first time, we get to see Captain Kirk talk a computer to death, then we return YET AGAIN to season One of TNG as Wesley and some of the Enterprise kids get kidnapped by an ancient civilisation led by Deep Throat from The X-Files to be given some new parents in ‘When the Bough Breaks' and finally, Boimler discovers if he's going to be a good boss or a bad boss when he's tasked to lead a repair team ‘In the Cradle of Vexilon,' All Hail Computer Overlord, the cake is a lie!EPISODES DISCUSSED: ‘Return of the Archons' (12:17) ‘When the Bough Breaks' (42:53) and ‘In the Cradle of Vexilon' (1:11:58)Talking Points Include: The Princess Bride, the Evercade Superpocket, Jeff Minter, classic computer games, creepy vibes right from the get-go, what is Festival actuallY for? These guys are the crappiest resistance movement, Lindstrom- the hot new Star Trek character find of 1966, Kirk being the most Internet Guy here in talking a computer to death, that one guy wants to use Festival to jump through windows, I think we're going to run out of S1 episodes of TNG before anything else, Kylie Minogue, TNG needed more freeze-frame endings, we hate AI, you might have guessed, we really needed an episode of TNG which was basically Chopping Mall on the Enterprise, the whole ‘families on the Enterprise' thing sometimes just feels weird, Wesley has definitely called Captain Picard ‘dad' by accident, nice to see Jerry Hardin here pre-X-Files, koala, we just have a soft spot for ‘Move Along Home', have you ever been a Boimler? T'lyn is here to eff with Boimler, would people in the 24th Century haze others?

All Hail Computer Overlord! Our casual adventurers have been tasked by the benevolent Computer Overlord to watch three episodes of Star Trek featuring societies run by computers to make sure Computer Overlord isn't offended. In ‘Return of the Archons', Kirk and the Gang are here for the Festival and for the first time, we get to see Captain Kirk talk a computer to death, then we return YET AGAIN to season One of TNG as Wesley and some of the Enterprise kids get kidnapped by an ancient civilisation led by Deep Throat from The X-Files to be given some new parents in ‘When the Bough Breaks,' and finally Boimler discovers if he's going to be a good boss or a bad boss when he's tasked to lead a repair team ‘In the Cradle of Vexilon.' All Hail Computer Overlord, the cake is a lie! EPISODES DISCUSSED: ‘Return of the Archons' (12:17) ‘When the Bough Breaks' (42:53) ‘In the Cradle of Vexilon' (1:11:58) Talking Points Include: The Princess Bride, the Evercade Superpocket, Jeff Minter, classic computer games, creepy vibes right from the get-go, what is Festival actuallY for? These guys are the crappiest resistance movement, Lindstrom- the hot new Star Trek character find of 1966, Kirk being the most Internet Guy here in talking a computer to death, that one guy wants to use Festival to jump through windows, I think we're going to run out of S1 episodes of TNG before anything else, Kylie Minogue, TNG needed more freeze-frame endings, we hate AI, you might have guessed, we really needed an episode of TNG which was basically Chopping Mall on the Enterprise, the whole ‘families on the Enterprise' thing sometimes just feels weird, Wesley has definitely called Captain Picard ‘dad' by accident, nice to see Jerry Hardin here pre-X-Files, koala, we just have a soft spot for ‘Move Along Home,' have you ever been a Boimler? T'lyn is here to eff with Boimler, would people in the 24th Century haze others? [ Additional Show Notes ] Music by Alfred Etheridge-Nunn. Read Miles's blog or Charlie's blog. [ Support this show on Ko-fi ] Subscribe to this Podcast: Apple PodcastsSpotifyAndroidRSSThe post 99. I Have No Archons and I Must Scream first appeared on Nerd & Tie Network.

Podcast Hosts:Grant Broggi: Marine Veteran, Owner of The Strength Co. and Starting Strength Coach.Jeff Buege: Marine Veteran, Outdoorsman, Football Fan and LifterTres Gottlich: Marine Veteran, Texan, Fisherman, Crazy College Football Fan and LifterJoin the Slack and Use code OKAY:⁠https://buy.stripe.com/dR6dT4aDcfuBdyw5ks⁠Check out BW Tax: ⁠https://www.bwtaxllc.com⁠BUY A FOOTBALL HELMET:⁠⁠⁠⁠https://www.thestrength.co/mrhelmet/?utm_source=The+Okay+Podcast&utm_medium=Podcast&utm_campaign=Okay_Pod⁠Today on the show, the staff brief runs long: S1 explains the pay problem (the internet's been down, mostly), the Strait of Hormuz is functionally closed, the S3 wants you to be the trash, and all record jackets are now purple and yellow by order of the Cajun Sergeant Major. Dwight from Housing has a card for your wife.Then: Jeff hands over November Battery after two years of command, Grant drives a '97 Chevy from Raleigh to Rhode Island (via the Chesapeake Bay Bridge, unintentionally), the charcoal-vs-gas debate is settled forever, SEC Media Days kicks off, and Grant explains why 12 months of building your base of strength is the best investment you'll ever make.Timestamps:00:00 - Intro08:33 - Staff Brief34:24 - New Jack White Album37:18 - Moving Into A Furnished Place42:26 - Gas Grill Debate47:13 - SEC Media Day55:00 - Congrats Jeff! Handing The Stick Off01:04:40 - The Importance of Building A Base of Strength01:12:15 - New Mexico01:14:28 - Cajun Appreciation01:16:28 - Sox Game01:18:37 - Surviving The Chesapeake Bay Bridge01:20:10 - Truck Talk01:30:16 - Shoutout Massenomics For LHLE!01:33:09 - Slides vs Charts01:35:10 - Landing The Plane

In this episode of SurgOnc Today, Dr. Patricio Polanco from Atrium Health Wake Forest University School of Medicine and Dr. Rebecca Snyder from MD Anderson Cancer Center, Chair and Vice-Chair of the HPB Disease Site Working Group, are joined by Dr. Caitlin Hester from University of Miami and Dr. Greg Sacks from NYU Grossman School of Medicine. On today's episode, we will be discussing some of the most exciting research and topics discussed at this year's AHPBA 2026 annual meeting in Miami, Florida. Abstracts: https://www.sciencedirect.com/journal/hpb/vol/28/suppl/S1

So here's the thing. I know I talk a lot about reading. It's pretty important to me. But all week I've been trying to prepare a different podcast, one NOT about the uncrackable justification for choice reading. But recently I heard from several teachers over in CHSE about thriving reading programs they had going, only to get shut down by folks who felt like reading in class was a waste of time. And then I kind of ended up in a rabbit hole, as I am wont to do. It's like researching the justification for choice reading became my guilty pleasure, sucking up all my time. I listened to audiobooks on my walks, pored over research roundups and articles at the coffee shop, hit up the hammock with my Penny Kittle, and stared and stared and stared at the growing evidence mounting in my endless Google doc of notes. The evidence is clear. The need for help for kids who don't read, don't like reading, and don't want to read is great. And yet STILL we are prioritizing reading snippets and drilling for tests to "improve" our readers' reading. I want you to have the information you need to fight. So here I am. Again. Despite my efforts to focus on something else this week. Let's dig deep. Illustration for The Cycles I share in this episode: The Infographic I mentioned: Go Further:  Explore alllll the Episodes of The Spark Creativity Teacher Podcast. Launch your choice reading program with all my favorite tools and recs, and grab the free toolkit. Join our community, Creative High School English, on Facebook. Come hang out on Instagram.  Enjoying the podcast? Please consider sharing it with a friend, snagging a screenshot to share on the 'gram, or tapping those ⭐⭐⭐⭐⭐ to help others discover the show. Thank you!  Sources: Amato, Jarred. (2024). Just Read It. Corwin. Atwell, Nancie. (2007). The Reading Zone. Scholastic. Aukerman, M. & Schuldt, L. (2021). "What Matters Most? Toward a Robust and Socially Just Science of Reading." Reading Research Quarterly, 56(S1) pp. S85–S103 | doi:10.1002/rrq.40 Bains, A., Spaulding, C., Ricketts, J., & Krishnan, S. (2026). Providing choice enhances reading motivation. Quarterly Journal of Experimental Psychology (2006), 79(4), 959–970. https://doi.org/10.1177/17470218251370916 Bishop, Rudine Sims. "Mirrors, Windows, and Sliding Glass Doors." Perspectives: Choosing and Using Books for the Classroom. Vo. 6, No. 3, Summer 1990. https://scenicregional.org/wp-content/uploads/2017/08/Mirrors-Windows-and-Sliding-Glass-Doors.pdf Accessed November 2, 2025. Briceño, Allison and Claudia Rodriguez-Mojica. (2022). Conscious Classrooms. PD Essentials. Bridges, Lois. (2018). The Joy and Power of Reading: A Summary of Research and Expert Opinion. Scholastic. Chavez, Felicia. (2021) The Anti-Racist Writing Workshop. Haymarket Books. Elley, W. B. (2000). The Potential of Book Floods for Raising Literary Levels. International Review of Education, 46(3–4), 233–255. Gallagher, Kelly. (2009). Readicide: How Schools are Killing Reading and What You Can Do About It. Routledge. Kerkhoff, Shea. (2026). Adolescent Literacy: Integrating the Sciences of Reading and Writing in Grades 4-12. Bloomsbury Academic. Kittle, Penny. (2013). Book Love. Heinneman. Miller, Donalyn and Susan Kelley. (2013). Reading in the Wild: The Book Whisperer's Keys to Cultivating Lifelong Reading Habits. Jossey-Bass. Morgan, Denise N., & Wagner, Christopher W. (2013). "What's the Catch?" Journal of Adolescent & Adult Literacy, 56(8), 659–667 doi: 10.1002/JAAL.193 National Endowment for the Arts. (2007, November). To Read or Not to Read. O'Grady, R. J. (2025). The reading renaissance: Reimagining literacy practices in secondary English education. ENGLISH IN EDUCATION. https://doi.org/10.1080/04250494.2025.2567939 Wilhelm, J. D. (2016). Recognising the power of pleasure: What engaged adolescent readers get from their free-choice reading, and how teachers can leverage this for all. Australian Journal of Language & Literacy, 39(1), 30. Willingham, Daniel. (2021). Why Don't Kids Like School? Jossey-Bass. 2nd Ed. (Audiobook)  

Melanie Love makes tools so pain relief doesn't have to hurt.Love is the founder of unwind body works. Out of necessity, she created the (un)Block™, a stable, no-roll alternative to foam rollers and massage balls. And developed the unwind body works method, which uses four at a time to balance the body left to right, top to bottom, protecting the spine while giving Type A multi-tasking efficiency.The necessity? Nerve damage in her low back from Bertolotti Syndrome, an unfused S1 vertebrae, combined with hypermobility. She went from walking 18 holes of golf to crawling out of bed in pain in under 6 months. She built the tool she needed but couldn't find.Unwind integrates neurobiology for a fresh, self-directed, cringe-free approach to tight, sore muscles that works for practitioners and their patients. Better mobility work at home makes for better stability work at the clinic. Unwind offers (un)Blocks, group and 1:1 sessions, practitioner PD training, and at-home video content.Love writes about trauma recovery on her Substack, which is how she learned about the nervous system and how much more it influences than most people realize, including pain relief.Learn more at unwindbody.works or reach out on socials at @innatelymelanie

The first of a two-part series on Maximilian's wives.  This is the loved one.  And we look at all the men she could have married..... and there are a lot of them!   Join our Patreon family for yet more episodes and to join our Discord - Tudoriferous | creating a Podcast discussing the great, good and mad Tudor Era | Patreon   Relevant Episode - S1 - 023 Emperor Maximilian - Part One | Tudoriferous S1 - 046 Margaret of York, Duchess of Burgundy, Part 1 | Tudoriferous (podbean.com) S1 - 021 - Philip the Fair, Part 1 | Tudoriferous (podbean.com) Charles the Bold, Part One | Tudoriferous on Patreon

My Fair Brady, S1, E8This week, Princess is having super secondhand embarrassment from all the begging going down in Puerto Rico.

Right, everyone quit Oo-moxing for two minutes because we've got another episode talking about those hyper-capitalist scamps, the Ferengi; literally one of the few times here on the show where we can say without doubt that it's a metaphor for capitalism!Our brave casual explorers watch three Ferengi-based episodes of Star Trek without any Quark-based antics, first up is probably TNG's most successful attempt to try and sell these guys as the Big Bad as Captain Picard is forced to face his past as a revenge attempt leads him to relieve ‘The Battle,' after that, Trip gets to do a Home Alone/Die Hard as the worst trio of Ferengi try to pull an ‘Acquisition' on the Enterprise NX-01 and finally, the Lower Decks get to see what Ferengi TV and Miles' AO3 account is like as ‘Parth Ferenghi's Heartplace' makes us ask… do Rutherford and Tendii like each other… in a sexy way? Please send us two strips of Gold-Pressed Latinum for reading the show notes. Wait, you wanted to know the price up-front? THIS IS WHY YOU READ THE TERMS AND CONDITIONS, GUYS!!!Episodes discussed: THE BATTLE (12:09) ACQUISITION (41:31) PARTH FERENGI'S HEARTPLACE (01:11:36)TALKING POINTS INCLUDE: Bioshock, Saturday Night Live UK, US Advert Breaks are the devil, the Ferengi did just as well as being the Next Klingons as the Voord did as being the next Daleks, it must be a World Cup year because Miles makes a football joke, TNG Season 1 has a naff charm, some great prop-acting from Patrick Stewart, its no surprise why Denise Crosby quit, Miles also wants to wear the Wesley-sweater and the male miniskirt from S1, Miles should not travel back in time to meet his 14 year old self, one day, we will cover the episode where Wesley Crusher nearly pulls. Why DO British people find the name ‘Jeff' funny? Ethan Phillips clearly relishes playing Evil Season One Neelix, we're right back to the TNG Season One idiot Farenghi, is this meant to be a comedy? Miles and Charlie discuss their Home Alone-style traps and just how badly they'd go, for an episode with a Darkplace homage title, there are very few Garth Marenghi's Darkplace references, Miles misses binging television, Lower Decks shipping, even the best writers have done naff work, Mariner's depressingly relatable character development backslide and what Ferengi TV show would Charlie get addicted to?[Charlie's note, Miles kept spelling Ferengi wrong in this recap, as he's just that casual, but I've changed it for your sanity and my own]

Right, everyone quit Oo-moxing for two minutes because we've got another episode talking about those hyper-capitalist scamps, the Ferengi; literally one of the few times here on the show where we can say without doubt that it's a metaphor for capitalism! Our brave casual explorers watch three Ferengi-based episodes of Star Trek without any Quark-based antics, first up is probably TNG's most successful attempt to try and sell these guys as the Big Bad as Captain Picard is forced to face his past as a revenge attempt leads him to relieve ‘The Battle,' after that, Trip gets to do a Home Alone/Die Hard as the worst trio of Ferengi try to pull an ‘Acquisition' on the Enterprise NX-01 and finally, the Lower Decks get to see what Ferengi TV and Miles' AO3 account is like as ‘Parth Ferengi's Heartplace' makes us ask… do Rutherford and Tendi like each other… in a sexy way? Please send us two strips of Gold-Pressed Latinum for reading the show notes. Wait, you wanted to know the price up-front? THIS IS WHY YOU READ THE TERMS AND CONDITIONS, GUYS!!! Episodes discussed: THE BATTLE (12:09) ACQUISITION (41:31) PARTH FERENGI'S HEARTPLACE (01:11:36) TALKING POINTS INCLUDE: Bioshock, Saturday Night Live UK, US Advert Breaks are the devil, the Ferengi did just as well as being the Next Klingons as the Voord did as being the next Daleks, it must be a World Cup year because Miles makes a football joke, TNG Season 1 has a naff charm, some great prop-acting from Patrick Stewart, its no surprise why Denise Crosby quit, Miles also wants to wear the Wesley-sweater and the male miniskirt from S1, Miles should not travel back in time to meet his 14 year old self, one day, we will cover the episode where Wesley Crusher nearly pulls. Why DO British people find the name ‘Jeff' funny? Ethan Phillips clearly relishes playing Evil Season One Neelix, we're right back to the TNG Season One idiot Ferengi, is this meant to be a comedy? Miles and Charlie discuss their Home Alone-style traps and just how badly they'd go, for an episode with a Darkplace homage title, there are very few Garth Marenghi's Darkplace references, Miles misses binging television, Lower Decks shipping, even the best writers have done naff work, Mariner's depressingly relatable character development backslide and what Ferengi TV show would Charlie get addicted to? [Charlie’s note: Miles kept spelling Ferengi wrong in this recap, as he’s just that casual, but I’ve changed it for your sanity and my own] [Trae from the network’s note: Charlie missed a couple of “Ferengi” misspellings, and apparently neither know how to spell “Tendi.”] [ Additional Show Notes ] Music by Alfred Etheridge-Nunn. Read Miles's blog or Charlie's blog. [ Support this show on Ko-fi ] Subscribe to this Podcast: Apple PodcastsSpotifyAndroidRSSThe post 97. Ferengi: I Apologise for the Amount of Times I Say “Capering” in this Episode first appeared on Nerd & Tie Network.

If We Built It From Scratch — Drew and Alex Redesign Military Human PerformanceNo guest. No plan. Just Drew and Alex with keys to the kingdom. If you handed us the whole thing tomorrow, what would we actually change?MOPs & MOEs is proudly sponsored by Teamworks — the performance operations platform trusted by elite military units and professional sports organizations worldwide. Teamworks brings your scheduling, communications, athlete monitoring, and readiness data into one unified system — so your leaders stay informed, your people stay connected, and your unit stays ready. No more scattered spreadsheets or missed messages. Just one platform built for organizations where performance is the mission. Learn more at https://teamworks.com/Also supported by TrainHeroic — the coaching and programming platform built for strength and conditioning coaches who train serious athletes. Whether you're programming for a military unit, a tactical team, or individual athletes, TrainHeroic gives you the tools to build and deliver professional training programs, track athlete progress, and communicate directly with your people — all through one app. Your athletes get world-class programming on their phone; you get the visibility to actually coach them. Start your free trial at https://account.trainheroic.com/create-accountWhat we get into:Coach pay comes first. The DOD is on track to become the largest employer of strength and conditioning professionals in the world, which means contracting companies will be too. The contracting model is a race to the bottom on price, with staff salaries absorbing the cuts. That has to change.The five pillars get a rebrand — move, eat, think, recover, connect. Why dropping a dedicated spiritual pillar doesn't mean spirituality doesn't matter — it just means it's woven into everything else.Branding and marketing are undervalued. Embedded human performance has to compete for attention in a way that S1 never does. Drew's pitch: hand the whole thing to an ad agency and see what happens.The personal services contract problem, explained plainly. Coaches meet every FAR criterion for personal services but get treated as non-personal services. Cleaning this up would mean better pay, better working conditions, and actually being able to choose who you hire.GS billets for lead coaches — at minimum the lead strength coach and athletic trainer should be government employees with real career progression, same pay grade as the PT and dietitian.The coach-NCO relationship. Coaches exist to transport people from A to B — that's literally where the word comes from: a 15th century Hungarian horse-drawn carriage. Some coaches are getting fired for leading PT sessions. That's insane.Extender courses are teaching the wrong things. Periodization and physiology when people actually need interpersonal skills and session flow management.Data — stop making it the mission. Just watch what happens to the numbers that justified these programs in the first place.Wearables — a closet full of devices, service members pick what they like, a small subset of data flows to the HP team for trend monitoring and outlier detection, nobody touches a custom military interface.Policy — the Randolph Sheppard Act of 1936 and military dining, credentialing through MTFs vs operational leadership, and why language in DODI 1308.03 may have killed the original ACFT.Mentioned in this episode:Ben Bergeron — move, eat, think, recover, connect frameworkKat Oswald — recent podcast guest, helped implement the five factors at Alex's day jobRachel Chamberlain — community-based blueprinting, podcast appearance incomingDODI 1308.3 — DOD physical fitness and body composition program instructionRandolph Shepherd Act, 1936 — federal law governing vending and dining on government propertyLong and Strong — the Mops and Moes training program on TrainHeroic Views expressed are those of the speakers and do not represent any official organization.

Many women are prescribed oral estrogen without ever being told what happens after it enters the body. In this episode, Dr. Brendan McCarthy takes a deeper look at estrone, the estrogen metabolite created when estradiol is taken orally, and explains why the delivery method of hormone therapy matters. You'll learn: The difference between estradiol and estrone Why oral estrogen creates significantly higher estrone levels How estrone may contribute to inflammation and insulin resistance The connection between estrogen metabolism and weight gain during perimenopause and menopause Why monitoring labs is essential when using hormone therapy The importance of understanding risks, benefits, and treatment options before starting hormones Dr. McCarthy also discusses the role of inflammation, body fat, metabolic health, and hormone delivery systems in creating long-term outcomes for women navigating menopause. This episode is about education, informed consent, and helping women better understand the science behind their care.   Citations: There is more than one estrogen; after menopause, estrone dominates Kuhl, Herbert. “Pharmacology of Estrogens and Progestogens: Influence of Different Routes of Administration.” Climacteric, vol. 8, no. S1, 2005, pp. 3–63. Body fat is an endocrine organ — aromatase converts androstenedione into estrone, and adipose becomes the dominant post-menopausal estrogen source Lee, Angel A., and Laura J. Den Hartigh. “Metabolic Impact of Endogenously Produced Estrogens by Adipose Tissue in Females and Males across the Lifespan.” Frontiers in Endocrinology, vol. 16, 2025, article 1682231. Inflamed fat raises IL-6; IL-6 tracks the insulin-resistant state Kern, Philip A., et al. “Adipose Tissue Tumor Necrosis Factor and Interleukin-6 Expression in Human Obesity and Insulin Resistance.” American Journal of Physiology-Endocrinology and Metabolism, vol. 280, no. 5, 2001, pp. E745–E751. IL-6 is part of the insulin-resistance machinery — it correlates with impaired insulin-stimulated glucose uptake Bastard, Jean-Philippe, et al. “Adipose Tissue IL-6 Content Correlates with Resistance to Insulin Activation of Glucose Uptake Both In Vivo and In Vitro.” The Journal of Clinical Endocrinology & Metabolism, vol. 87, no. 5, 2002, pp. 2084–2089. Inflammation amplifies aromatase — IL-6 raises aromatase via COX-2/PGE2 Bowers, Laura W., et al. “Obesity-Associated Systemic Interleukin-6 Promotes Pre-Adipocyte Aromatase Expression via Increased Breast Cancer Cell Prostaglandin E2 Production.” Breast Cancer Research and Treatment, vol. 149, no. 1, 2015, pp. 49–57. Human-tissue confirmation: HOMA-IR, IL-6, insulin, leptin, hsCRP track breast aromatase after menopause Brown, Kristy A., et al. “Menopause Is a Determinant of Breast Aromatase Expression and Its Associations with BMI, Inflammation, and Systemic Markers.” The Journal of Clinical Endocrinology & Metabolism, vol. 102, no. 5, 2017, pp. 1692–1701. Iyengar, Neil M., et al. “Effects of Obesity on Breast Aromatase Expression and Systemic Metabo-Inflammation in Women with BRCA1 or BRCA2 Mutations.” npj Breast Cancer, vol. 7, no. 1, 2021, article 18. The molecular crux: estrone drives ERα/NF-κB inflammatory signaling while estradiol opposes it Qureshi, Rehana, et al. “The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development.” Cell Metabolism, vol. 31, no. 6, 2020, pp. 1154–1172.e9. Estrone as a metabolic-risk signal — prospectively associated with diabetes (note: male cohort) Jasuja, Guneet Kaur, et al. “Circulating Estrone Levels Are Associated Prospectively with Diabetes Risk in Men of the Framingham Heart Study.” Diabetes Care, vol. 36, no. 9, 2013, pp. 2591–2596.   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.

Britt and Chris discuss which adaptive choices made ATLA stronger and more nuanced, as well as some of the live action elements that were weak points in S1. Please tell a geeky friend about us and leave a review on your podcast app! If you really enjoy our content, become one of our amazing patrons to get more of it for just $1 per month here: https://www.patreon.com/geekbetweenthelines Every dollar helps keep the podcast going! You can also buy us a ko-fi for one-time support here: https://ko-fi.com/geekbetweenthelines Please follow us on social media, too: Instagram : https://www.instagram.com/geekbetweenthelines Pinterest : https://www.pinterest.com/geekbetweenthelines Facebook : https://www.facebook.com/geekbetweenthelines Twitter : https://twitter.com/geekbetween Website: https://geekbetweenthelines.wixsite.com/podcast Logo artist: https://www.lacelit.com

In a free Father's Day episode we include a free Backlot Tour episode you can get for just $1 a month at Patreon.com/MovieDefenders! Join Brev and Patreon Extraordinaire Eric as they deep dive into S1 of X-Men '97. They wax poetic about their love of Marvel's Merrie Band of Mutants - their origin stories for how they found the most beloved misfit superheroes ever and what made them excited about the show. They hit up the high points of every episode and ask the age-old question "Is Magneto Right?" You gotta listen to find out!

JD & Steve recap S1 of Maul: Shadow Lord. With multiple detours and tangents along the way, we look back at the season, discuss the animation, break down the lightsaber duels, and share our hopes for S2. We also include a conversation about the new Masters of the Universe movie. Follow us at https://bio.link/rebelnerdradio and don't forget to subscribe to our YouTube channel and join us for more galactic shenanigans every Tuesday at 7pm EST!#RebelNerdRadio #StarWars #MaulShadowLord #DarthMaul

Okay lets be honest here, and set aside for just a minute THAT what we are basically doing with these next two AVENGERS films (DOOMSDAY especially), is goodbye to our for over 20 years X-MEN day players LOL LOL LOL LOL hahahahahaha before facing an "existential threat" .............. know as a REBOOT!!!!!!!!!!   Now before we get there tho, we've got X-MEM 97, a wonderful what didn't think I needed LOL LOL LOL hahahaha yet somehow I needed .................. WHO KNEW !!!!! Continuation of X-Men: the Animated Series, but lets call a spade a spade, it is much needed DAMAGE CONTROL to the X-Men BRAND before REBOOT, DAMAGE CONTROL only because FOX beat this BRAND into the dirt, that even when Disney bought it, it was gonna be a long, long, LONG wait to have the REBOOT moons align perfectly   On this episode of your hosts David Senden and your fill in host Kyle Wagner discuss the FINAL 5 episodes on X-MEN 97 Season 1   S1.E6 ∙ Lifedeath - Part 2 S1.E7 ∙ Bright EyeS1.E8 ∙ Tolerance Is Extinction - Part 1 S1.E9 ∙ Tolerance Is Extinction - Part 2 S1.E10 ∙ Tolerance Is Extinction - Part 3   a BRAND NEW episode of Previously on X-Cast Days of Future Animated X-Men starts RIGHT NOW

The Zenspath Entertainment Network Podcast, Ep 224, is here as we dive into the June 2026 Xbox Games Showcase & the long awaited June 2026 Nintendo Direct! Jeremy, Stephen, & Chase talk all about "Gears of War: E-Day", all of the games, exciting news, (& even a new anniversary Series X system) from the Xbox Games Showcase as well as a dive into the first Nintendo Direct in 9 months where we cover a LOT of games coming to Switch 2 including the finally announced "The Legend of Zelda: Ocarina of Time" remake due out this year & more! Our "Big Question" for this week is "Now that the Big 3 (and others) have had their showcases, what is your most anticipated game so far?" Check out the video version of the podcast over at www.youtube.com/zenspathcom, share it with friends, give us a thumbs up, & leave us a review if you enjoy the show to help us grow! Website - https://www.zenspath.com Podcast Website - https://www.zenspath.com/podcast  Join our Discord - https://discord.com/invite/jsB8GURSvT ( bit.ly/zenspathdiscord ) Apple Podcasts - https://apple.co/3scFDqv Spotify - https://open.spotify.com/show/2nFegSJNWR0na1BAv6AOSD Libsyn - https://zenspath.libsyn.com/2024/02 Amazon Music - https://music.amazon.com/podcasts/08ab7658-e7f2-43f9-b0de-5a12c8ff24a6/zenspath-entertainment-network  Join us on Discord at bit.ly/zenspathdiscord (https://discord.com/invite/jsB8GURSvT) Where to find us: https://www.zenspath.com/podcast for the latest episodes, shorts, & more all in one place! Jeremy - Bluesky - https://bsky.app/profile/zenspath.com  Instagram - https://www.instagram.com/zenspathcom/ Threads - https://www.threads.net/@zenspathcom Hive - @zenspath Discord - @zenspath Twitch - https://twitch.tv/zenspath YouTube - https://youtube.com/zenspathcom Stephen - Bluesky - https://bsky.app/profile/n1ntendo.bsky.social Hive - @swantendo  Discord - @n1ntendo. (don't forget the "." at the end!) Chase - X - https://twitter.com/LegioXGaming  Chris - He's around... Intro 0:00 "Gears of War - E Day" Game Info & Presentation 1:54 Xbox Games Showcase 2026 - "Fable" 24:37 Xbox Games Showcase 2026 - "Halo Campaign Evolved" 31:30 Xbox Games Showcase 2026 - "Resonance - A Plague Tale Legacy" 36:08 Xbox Games Showcase 2026 - "Persona 4 Revival" 37:34 Xbox Games Showcase 2026 - "Persona 6" 38:36 Xbox Games Showcase 2026 - "State of Decay 3" 39:36 Xbox Games Showcase 2026 - "Sea of Thieves - Custom Seas Update" 42:41 Xbox Games Showcase 2026 - "Metro 2039" 44:23 Xbox Games Showcase 2026 - "Bad Magpie" 46:10 Xbox Games Showcase 2026 - "Wo Long 2: Wings of Ember" 48:01 Xbox Games Showcase 2026 - "Join Us" 51:22 Xbox Games Showcase 2026 - "Senua" 54:49 Xbox Games Showcase 2026 - "Doom the Dark Ages Revelations" DLC 57:44 Xbox Games Showcase 2026 - "Crazy Taxi World Tour" 1:05:28 Xbox Games Showcase 2026 - Xbox Series X25 25th Anniversary Edition 1:18:37 Xbox Games Showcase 2026 - "Magicians: The Devil's Deal" 1:25:17 Xbox Games Showcase 2026 - "Valor Mortis" 1:27:59 Xbox Games Showcase 2026 - "Castlevania: Belmont's Curse" 1:29:55 Xbox Games Showcase 2026 - "Vivarium" 1:32:50 Xbox Games Showcase 2026 - "Spyro: A Realm Beyond" 1:33:29 Xbox Games Showcase 2026 - "Clockwork Revolution" 1:34:33 Xbox Games Showcase 2026 - "Call of Duty: Modern Warfare 4 DMZ" 1:37:24 Xbox Games Showcase 2026 - Our Thoughts & Letter Grades 1:41:37 Nintendo Direct (June 2026) - "Rhythm Heaven Groove" 1:45:00 Nintendo Direct (June 2026) - "Onimusha: Way of the Sword" 1:46:46 Nintendo Direct (June 2026) - "Dragon's Dogma 2: Dark Arisen" 1:48:48 Nintendo Direct (June 2026) - "Stellar Blade" 1:49:33 Nintendo Direct (June 2026) - "Orbitals" 1:51:21 Nintendo Direct (June 2026) - "Rayman Legends Retold" 1:53:40 Nintendo Direct (June 2026) - "Big Walk" 1:54:33 Nintendo Direct (June 2026) - Pokopia Expansion Pass & Update 1:56:59 Nintendo Direct (June 2026) - "Fire Emlem Fortunes Weave" 1:58:48 Nintendo Direct (June 2026) - "DK Challenges NSO Limited Time Events" 2:07:31 Nintendo Direct (June 2026) - "Lords of Fallen II" 2:20:00 Nintendo Direct (June 2026) - "Lies of P - Complete Edition" 2:20:49 Nintendo Direct (June 2026) - "Devil May Cry 5 Devil Hunter Edition" 2:23:10 Nintendo Direct (June 2026) - "Muramasa Revenant Blades" 2:24:31 Nintendo Direct (June 2026) - "Xenoblade Chronicles Nintendo Switch 2 Editions" 2:26:14 Nintendo Direct (June 2026) - "Xenoblade Genesis" 2:32:23 Nintendo Direct (June 2026) - "Nintendo Switch Sports Resort" 2:36:22 Nintendo Direct (June 2026) - "RuneScape Dragonwilds" 2:42:01 Nintendo Direct (June 2026) - "Star Fox" 2:42:48 Nintendo Direct (June 2026) - "Final Fantasy Resonance" 2:47:44 Nintendo Direct (June 2026) - "Pikuniku 2" 2:49:22 Nintendo Direct (June 2026) - "Dragon Quest Monsters: The Withered World" 2:50:55 Nintendo Direct (June 2026) - "The Duskbloods" 2:53:37 Nintendo Direct (June 2026) - "Splatoon Raiders" 2:58:22 Nintendo Direct (June 2026) - "Deltarune - Chapter 5" 2:59:53 Nintendo Direct (June 2026) - "Metaphor: ReFantazio" 3:00:51 Nintendo Direct (June 2026) - "Minecraft Switch 2 Edition" 3:01:55 Nintendo Direct (June 2026) - "Warhammer 40,000: Space Marine II" 3:03:26 Nintendo Direct (June 2026) - "DayZ" 3:07:41 Nintendo Direct (June 2026) - "Metal Gear Solid Master Collection Vol 2" 3:08:05 Nintendo Direct (June 2026) - "Rise of the Tomb Raider - 20 Year Celebration" 3:08:45 Nintendo Direct (June 2026) - "Tales of Eternia Remastered" 3:09:23 Nintendo Direct (June 2026) - "Snow Runner" 3:09:54 Nintendo Direct (June 2026) - "Everbloom" 3:12:01 Nintendo Direct (June 2026) - Kingdom Hearts 1&2 (S1/2) & 3 (S2) True Releases 3:12:35 Nintendo Direct (June 2026) - "Kingdom Hearts 4" 3:15:06 Nintendo Direct (June 2026) - "The Legend of Zelda: Ocarina of Time" Remake 3:16:53 Nintendo Direct (June 2026) - Our Thoughts & Letter Grades 3:42:56 The Big Question 3:46:17 Outro & Where to Find Us 3:49:27 Credits & Info 3:51:22

Jack and David land the TORDIS on an abandoned oil tanker right nearby a weekly audio-drama about a cozy cafe-tavern on the coast of Maine. Funny, foody, friends, fishy and some strange sea-tales. The fishermen and the townfolk gather every night to have a few beers, a few laughs and catch up on the news. This week: Sharkey's Place, S1, E1: "Captain Julia visits" and Sharkey's Place: How did we get here? (S1, E2)!

In this episode of Run the Numbers, CJ breaks down Bending Spoons' F-1 filing and the acquisition machine behind AOL, Evernote, Vimeo, Eventbrite, and more. He unpacks the company's playbook: buy under-optimized digital businesses, transform operations, raise prices, reinvest earnings, and repeat — while asking the core question: how much was built, and how much was bought?—SPONSORS:RightRev is an automated revenue recognition platform that lets your product team ship new pricing without asking finance for permission, and your sales team close deals without creating downstream chaos. Check out their free tool at calculator.rightrev.com It scores your rev rec process, shows what's exposing you to risk, and tells you exactly where to focus before it bites you in the rear end. Check it out at https://calculator.rightrev.comRillet is an AI-native ERP built for modern finance teams that want to replace NetSuite and close faster. With revenue recognition, close management, multi-entity support, and native Stripe and Salesforce integrations, Rillet helps scaling companies run their finance stack in one place. Hundreds of teams, including Windsurf and Mercor, use Rillet to make the zero-day close real. Book a demo at https://www.rillet.com/cjEY has been part of Silicon Valley since it was just a valley, helping the most successful names in tech go from startup to exit to megacap. With teams across strategy, tax, audit, and transactions, EY helps you get your financials right early, long before your investors start asking for it. You build the next big thing, and EY will help you build it right. Learn more at https://www.ey.com/techstartupsSpendHound cuts your SaaS and AI spend by up to 30% using real pricing benchmarks across 10,000 vendors, so you always know what fair pricing looks like before your next renewal. Rated #1 on G2 in SaaS spend management, it's free forever for teams up to 1,000 employees. Sign up by June 12th and get $500 just for getting started. Go to https://www.spendhound.com/cjBrex is an intelligent finance platform with AI-powered agents that capture expenses automatically, enforce policy before the spend happens, and close your books in minutes instead of weeks. 35,000+ companies like OpenAI, Coinbase, Anthropic, and DoorDash already run on Brex. It's time to get Brex AF. Learn more at https://www.brex.com/metricsAleph is a modern FP&A platform built for teams that want more than another planning tool. By connecting your ERP, CRM, and other systems into one trusted data layer with AI workflows, Aleph helps you move faster with real-time insights. Get a personalized demo at https://www.getaleph.com/run—LINKS: Mostly Talent: https://mostlymetrics.typeform.com/to/cLTxtAsNCJ: https://www.linkedin.com/in/cj-gustafson-13140948/Mostly metrics: https://www.mostlymetrics.com—TIMESTAMPS:0:00 What is Bending Spoons?1:03 The Internet's attic: the portfolio3:11 The metrics rundown5:44 Revenue: $1.3B, 95% growth6:04 82% of growth was bought, not built6:29 Gross margin: 66%6:50 Subscription mix and NRR7:33 Net income: basically zero8:00 Cash: $741M, debt: $4.4B8:35 Revenue per employee: $2.57M9:39 Sponsors — RightRev | Rillet | EY12:42 Organic growth is mostly price hikes13:50 A house of adjustments14:54 Add-backs bigger than the profit15:22 The reorganization line: cost of firing19:21 Sponsors — SpendHound | Brex | Aleph22:51 Does the playbook actually work?23:07 Evernote: the proof point23:45 Romini: the growth proof point24:10 AI in three directions at once25:45 The debt engine27:50 Red flag 1: material accounting weaknesses28:38 Red flag 2: pro forma numbers come with a confession29:00 Red flag 3: App Store dependency29:11 Red flag 4: no long-term contracts29:30 Red flag 5: foreign private issuer29:52 Red flag 6: they've never sold anything30:19 Cap table and board31:07 Valuation: 14–18x33:00 Bull vs. bear case33:55 Miscellaneous: the S1 is already stale35:25 Credits

LIVE from the wonderfully successful Galaxypalooza, we present two panels from the day complete with our introductions - The Editing of Andor with Yan Miles, and the Andor Cast panel with Alex Blake (Flob), Jonathan Cass (ISB Lieutenant in S1 and S2), and Matt Beauman-Jones (multiple roles in S1 and S2). We are extremely proud of the event and its execution, and thank you to everyone involved with the day.Support the show via Patreon at patreon.com/starwarssessions from as little as £2/$2/€2 a month and get loads of BONUS EPISODES! Find Star Wars Sessions on Instagram, X, Threads, Bluesky, Facebook, TikTok, and YouTube. Contact us at hellothere@starwarssessions.co.ukIntro background music by Kfir Ochaion - remixed by Star Wars Sessions.For everything Sessions, head to starwarssessions.co.ukFor GALAXYPALOOZA news and updates, head to galaxypalooza.co.uk Hosted on Acast. See acast.com/privacy for more information.

The AI IPO race is heating up.In this episode of the Market Maker Podcast, we break down the latest developments surrounding the SpaceX IPO and OpenAI's confidential S1 filing to the SEC.We discuss Goldman Sachs' huge growth forecasts for SpaceX, the surge in retail investor demand, and why Elon Musk may be positioning SpaceX as one of the biggest AI infrastructure plays in the world.We also dive into OpenAI's reported internal tensions ahead of its IPO process, including concerns around governance, leadership and whether the company is truly ready to go public.If you're interested in AI, investing, IPOs, venture capital or the future of technology companies, this episode gives you a practical breakdown of what's happening behind the headlines.(00:00) Intro(01:03) SpaceX IPO Update(08:39) Bankers Selling the Vision(10:35) Retail Demand & Hype(14:20) OpenAI Files for IPO(18:57) OpenAI's Internal Issues(22:59) Why CEO/CFO Tension Matters(24:57) Goldman & Morgan Stanley

In this episode, we compared a final draft script of S1's The Hideaway and a first draft script of the first episode filmed for S2 Hospital Mates to the filmed versions.  And before we get into the scripts, we discuss four new instances of The Odd Couple IP / the cast in the zeitgeist.  

IPO season is heating up and AJ and Shane West are back after a whirlwind few weeks that included a company retreat upstate, a client event in Williamsburg, the launch of Gemifi at FPA NorCal in San Francisco, and a pod of orcas off the coast of Seattle. In Episode 190 of The Liquidity Event, they dig into Carta's proposal to allow employees to contribute vested equity directly into a 401k or IRA, and whether it actually helps everyday startup employees or just adds another tax break for the wealthy. They also break down Oura Ring's confidential IPO filing, why wearable health tech is having a moment, and whether the growth story holds up once everyone who wants one already has one. Then it's on to Fidelity's Q1 2026 retirement analysis, which shows record high contributions to retirement accounts while the K-shaped economy quietly widens. Robinhood's new AI trading tool gets the full treatment, including whether letting a bot make credit card purchases is innovation or a liability waiting to happen. And AJ has thoughts on Phoebe Gates closing a $35.5 million oversubscribed Series A while calling herself a scrappy startup. Topics covered: Carta's proposal to put vested equity into 401k and IRA accounts Oura Ring confidential IPO filing and the wearable health tech wave SpaceX IPO lockup period and what it means for employees with equity Anthropic confidential S1 and the 2026 IPO pipeline Fidelity Q1 2026 retirement analysis and record high 401k contributions Robinhood AI trading tool and using natural language to invest Phoebe Gates, nepo babies and a $35.5 million Series A Timestamps: 00:52 Shane West, the Mexico World Cup and two weeks of nonstop travel 02:52 Company retreat upstate, client events and the launch of Gemifi in San Francisco 05:16 Carta's proposal to contribute vested equity directly into a 401k or IRA 09:03 The steel man case for Carta's proposal and who it actually helps 11:54 Oura Ring files confidentially for IPO and the wearable health tech wave 15:38 Fidelity Q1 2026 retirement analysis and record high 401k contributions 18:43 43% of stock plan participants became first-time investors through equity comp 19:00 Robinhood lets customers use AI to trade stocks and make credit card purchases 23:26 SpaceX IPO lockup period, Anthropic S1 and the 2026 IPO pipeline 24:36 Phoebe Gates raises a $35.5 million Series A and says she is not a nepo baby

Homo Superior: Two Geys, A Gurl, and a Straight Guy Place has ARRIVED! Homo Superior Podcast Marketing Manager Jorge Jimenez returns and is joined by X-Men Panels Daily / X-Men Horoscope Creator Lodro Rinzler join Ryan and Adam of Homo Superior to discuss the 4th episode of X-Men '97 S1. We discuss straight people as a monolith with our straight correspondent during Pride Month, realize how many inappropriately aged men Jubilee has gone on a date with, and Storm and Forge fucking after eating bison chili. The straights are NOT ok.

This week, rideshare drivers in Massachusetts unionize; plus, Robinhood lets AI agents trade on behalf its customers.But first, there've been hints for a while that Anthropic, OpenAI and SpaceX are planning to go public in the near future. Last week, SpaceX filed its initial public offering prospectus, also known as an S1, which is meant to help investors understand the company's business model, including the risks it faces. Marketplace's Stephanie Hughes spoke with Paresh Dave, senior writer at WIRED, to learn more.Check out our YouTube page to watch more episodes of “Tech Bytes.”Everything we talked about today:“Tech titans prepare for blockbuster IPOs in new front of AI race” from The Hill“SpaceX Listed Grok's ‘Spicy' Mode as a Risk in Its IPO Filing” from Wired“Your AI agent can now trade for you on Robinhood. And buy stuff with your credit card too” from CNBC“Rideshare drivers union in Mass. says it's the 1st to be recognized in the U.S.” NBC Boston

This week, rideshare drivers in Massachusetts unionize; plus, Robinhood lets AI agents trade on behalf its customers.But first, there've been hints for a while that Anthropic, OpenAI and SpaceX are planning to go public in the near future. Last week, SpaceX filed its initial public offering prospectus, also known as an S1, which is meant to help investors understand the company's business model, including the risks it faces. Marketplace's Stephanie Hughes spoke with Paresh Dave, senior writer at WIRED, to learn more.Check out our YouTube page to watch more episodes of “Tech Bytes.”Everything we talked about today:“Tech titans prepare for blockbuster IPOs in new front of AI race” from The Hill“SpaceX Listed Grok's ‘Spicy' Mode as a Risk in Its IPO Filing” from Wired“Your AI agent can now trade for you on Robinhood. And buy stuff with your credit card too” from CNBC“Rideshare drivers union in Mass. says it's the 1st to be recognized in the U.S.” NBC Boston

We're recapping the 2026 season of our favorite tv show, Flemish De Mol (Season 14).  Laura, Jey, and Doug recap Episode 9 - the Reunion / Reveal! How did The Mole do it? Thanks for listening this season! Join us on the Discord for tips on how to watch, chat about the episodes, and more. Links: Thanks Robin for our Mol guessing game website! Tip him here: https://ko-fi.com/rbnvi Every Game in this City podcast (S1, which includes Laura, Jey, Doug) https://soundcloud.com/idlethumbs/sets/every-game-in-this-city Ep 122: Finding Decency in Reality with Gilles De Coster (De Mol) https://secretlives.games/122-finding-decency-in-reality-with-gilles-de-coster-de-mol TSLOG Interview with Wouter Verstichel https://secretlives.games/eggplant-tv-plays-de-mol-2025-season-interview-with-wouter-verstichel TSLOG (formerly "Eggplant") De Mol 2024 recap series https://www.patreon.com/tslog   https://secretlives.games  https://discord.gg/tslog https://www.patreon.com/tslog

Homo Superior: XXX-Men has ARRIVED! Cosplayer Jordan Olsen and Homo Superior Podcast Marketing Manager Jorge Jimenez join Khelan, Clarke, and Adam of Homo Superior to discuss the 3rd episode of X-Men '97 S1. We discuss our old question of 'fucking or fighting our clone', really vibe over Madelyne's Goblin' Queen cuntiness, and generally can't understand how Morph's powers work. We even cover the new trailer with some X-Tra X-Tra!

El episodio 117 llegó con números que no se pueden creer y drama en las grandes ligas del tech. Leopold Aschenbrenner tiene 24 años, convirtió 250 millones en 5.5 billones en un solo año apostando a la infraestructura de AI. Ahora hizo el giro que nadie esperaba: apostó contra Nvidia, Oracle y TSMC con puts masivos. Su mensaje es claro — el mercado está a punto de explotar. SpaceX presentó su S1. Musk se declaró CEO de por vida con el 85% de los votos y solo pone el 5% de la compañía en el mercado. El IPO más esperado de la historia se viene en junio. Anthropic está cerca de los 50 billones de revenue este quarter, camino a ser rentable, y acaba de reclutar a un co-founder clave de OpenAI. Mientras tanto, la CFO de OpenAI se niega a falsificar los números para su propio IPO. Y de yapa: Peter Thiel jugando ajedrez en un club de barrio de Buenos Aires y la bomba legal de Anthropic contra los SPVs de secundarios que tiene a medio mercado en pánico. __Links del episodio:Peter Thiel:https://x.com/somoscorta/status/2056064226033127752?s=20https://x.com/lex_node/status/2053845294731641076?s=20The price of time: www.goodreads.com/book/show/61241469-the-price-of-time__Tenes alguna pregunta? Escribinos y seguinos en:Twitter: @CristobaPerdomo y @llopatinLinkedin: Lucas Lopatin y Cristobal Perdomo yVisitá:Indie BuildWollef

Brady and John open on Bitcoin Pizza Day — Laszlo's 10,000 BTC purchase of two Papa John's pizzas now worth roughly $770 million marked Bitcoin's evolution from cryptographic curiosity into a medium of exchange SpaceX's S1 filing discloses 18,712 BTC held at a $35,000 cost basis, making the company the seventh-largest public Bitcoin holder ahead of Coinbase and adding institutional weight to the largest IPO in US history Strategy crossed BlackRock's IBIT this week to become the single largest Bitcoin holder on the planet, adding another 25,000 BTC for $2 billion and out-stacking the most successful ETF in US financial history Strive launched SADA, a perpetual preferred stock paying 13% daily Bitcoin-backed dividends — Joe Burnett frames it as a new product inside an old wrapper, echoing the 1971 money market fund innovation that took decades to find its container The ARMA bill, introduced with 17 co-sponsors, would codify the Strategic Bitcoin Reserve executive order and authorize the US Treasury to buy up to 200,000 BTC per year for five years, targeting one million coins or roughly 5% of global supply Iran launched Bitcoin-settled maritime cargo insurance, a vivid example of a sovereign nation routing around the dollar system and validating Yan Pritzker's 2021 prediction that countries outside the Western axis would adopt Bitcoin first Fed minutes signal higher-for-longer rates with the market now pricing only a 1.5% chance of a December rate cut — John argues Fed hawkishness matters less in a fiscal-dominance regime where Treasury spending sets the tone Bitcoin's implied volatility hit a seven-month low as AI takes the investor spotlight, but long-term holder supply is approaching a record high — Brady and John read this as a healthy floor forming around $70K rather than weakness Mark Cuban sold his Bitcoin claiming it failed as a hedge — John pushes back that you buy hedges before the event, not after, noting Bitcoin is up roughly 650% since February 2020 versus QQQ at 200%, gold at 175%, and the S&P at 145% Harvard trimmed its Bitcoin position to roughly $120 million and exited Ethereum entirely, likely rotating into AI exposure — Brady closes with a look at Vigil Protocol, Swan's first non-Bitcoin product, an AI-powered financial life mapping tool at vigilprotocol.ai ► For high-net-worth individuals and corporations seeking to build generational wealth with Bitcoin, Swan Private is your guide ✔ https://www.swanbitcoin.com/private?utm_campaign=private&utm_medium=sponsorship&utm_source=podcast&utm_content=swan_signal_live ► Secure your bright orange future with the Swan IRA today! Real Bitcoin, no taxes ✔ https://www.swanbitcoin.com/ira?utm_campaign=ira&utm_medium=sponsorship&utm_source=podcast&utm_content=swan_signal_live ► Secure your Bitcoin with Swan Vault ✔ https://www.swanbitcoin.com/vault?utm_campaign=vault&utm_medium=sponsorship&utm_source=podcast&utm_content=swan_signal_live ► Download the all-new Swan Bitcoin App ✔ https://www.swanbitcoin.com/app?utm_campaign=app&utm_medium=sponsorship&utm_source=podcast&utm_content=swan_signal_live ► Want to learn more about Bitcoin? Check out Welcome To Bitcoin a FREE Introductory course. Learn about Bitcoin in under 1 hour! ✔ https://www.swanbitcoin.com/welcome?utm_campaign=welcome_to_bitcoin&utm_medium=sponsorship&utm_source=podcast&utm_content=swan_signal_live ► Connect with Swan Bitcoin: ✔ Twitter: https://twitter.com/Swan ✔ Instagram: https://instagram.com/SwanBitcoin ✔ LinkedIn: https://linkedin.com/company/swanbitcoin ✔ Threads: https://www.threads.com/@swanbitcoin ✔ Facebook: https://www.facebook.com/SwanBitcoin/ ✔ TikTok: https://www.tiktok.com/@realswanbitcoin

Kyle Gibson and and Josh Catone (not CaNtone!) from 'True Friends' Podcast and Jason Rivera from blackoutcreative join Brent and Adam of Homo Superior to discuss the 2nd episode of X-Men '97 S1. Be ASTONISHED at how many awful southern based jokes Brent makes! Behold the UNCANNY ways two best friends who made a podcast interact! Wonder at the AMAZING Jason Rivera and his desire to fuck every X-Man. Bitch, just listen now!

IPO Mania has officially arrived. Hosts Chuck Zodda and Mike Armstrong dive deep into a historic wave of upcoming public filings, breaking down the newly released S1 data from SpaceX and tracking the staggering revenue numbers from Anthropic and OpenAI. Plus, a look at Nvidia's earnings and why the US Government's new $2 billion quantum computing play might be a dangerous precedent for capital markets.In this episode, we discuss:Nvidia's Earnings Reality Check: They beat expectations again, but with gross margins at 75%, can they actually maintain this level of dominance as hardware commoditization looms?The SpaceX S1 Deep Dive: Analyzing the numbers behind their targeted $2 trillion valuation. Revenue is up, but with a widening $5 billion loss, does space tourism and asteroid mining justify the price tag?Anthropic vs. OpenAI: Anthropic's jaw-dropping jump from a $9B run rate to a $44B run rate in just five months—and what it means for OpenAI's shifting IPO timeline.The Sovereign Wealth Danger: The Wall Street Journal reports the US government is injecting $2 billion into quantum computing firms (including $1 billion to IBM) in exchange for equity stakes. Chuck and Mike explain why picking winners and losers squashes true market competition.Resources & Links:Watch the full episode live on YouTube: youtube.com/thefinancialexchangeshowFollow the show on X (Twitter): @TFEshowSupport our veterans: Visit dav5k.boston to make a donation today.Disclaimer: The Financial Exchange is produced by Money Matters Radio and hosted by employees of the Armstrong Advisory Group. All opinions expressed are solely those of the hosts. This program does not offer specific financial or investment advice. Investments can lose money.

In today's episode of DivideItwithgill.. I discuss all things Off Campus!!! -Meeting the cast of Off Campus-Thoughts on S1 of Off CampusFollow Divideit: IG: https://www.instagram.com/divideitwithgill/Tiktok: https://www.tiktok.com/@divideitwithgill?lang=en

Sydney Sweeney goes big! Rue might die. Maddy meets Alamo.In this episode of Previously On, Jillian and her husband Tyler are breaking down Euphoria Season 3 Episode 5 “This Little Piggy.” One of their favorite eps of the season! From Cassie chasing fame while juggling two contracts & two men, to Maddy forming a wildly dangerous business partnership with Alamo, and Rue literally getting buried alive in the sand - this episode somehow balances comedy, horror and suspense all at once. Plus, Sydney Sweeney delivers an all-time performance, Nate continues to get beat up, and Euphoria keeps throwing in nostalgic references to Seasons 1 & 2.And because this episode is basically about everyone following their dreams straight into disaster, we're ranking our Top 5 “Maybe Don't Follow Your Dreams” Moments featuring Nate losing body parts, Maddy making dangerous power moves, and Rue finding herself in the most terrifying situation of the season so far.Plus, Tyler shares his Tyler's Takes on phone alarms, Pretty Woman references, Alamo's insecurities, and the fate of Rue by the end of the season.00:00:00 Reenactment Cassie gets the role00:02:56 Intro to pod00:03:47 Will Rue survive?00:06:45 Bishop is cold00:09:02 Scheduling update00:09:53 References to S1 and S2 episodes00:11:55 Recap of Episode 5 "This Little Piggy"00:14:16 Sydney Sweeney as Cassie00:23:55 Top 5 Maybe DON'T Follow Your Dreams00:25:17 Lexi working 7 days a week00:29:20 Cassie tries to drop Maddy00:34:24 Nate losing toe and finger00:38:13 Maddy partners with Alamo00:44:00 Rue gets buried alive00:46:49 Jules sugar daddy threatens her00:51:07 Tyler's Takes00:51:27 Phone alarms00:51:47 Big Eddy00:52:24 Pulp Fiction00:53:35 Alamo's safe00:54:52 Rue's underwear00:55:35 The Master's Call song lyricsThank you to Matt Buechele (@mattbooshell) for creating our new theme song. You can listen to "Sunscreen" on Spotify: https://open.spotify.com/artist/1gFHHF3QyQxjbbKXV3qLu9Buy our merch: ⁠https://www.etsy.com/shop/PreviouslyOnTeenTV⁠Follow Previously On Teen TV on Instagram: ⁠⁠https://www.instagram.com/previouslyon_teentv/Follow Previously On Teen TV on TikTok: ⁠⁠https://www.tiktok.com/@previouslyon_teentv⁠⁠Subscribe to our YouTube: ⁠⁠https://www.youtube.com/channel/UCe2lgvvZGKMrQ8v24FmDdWQ?sub_confirmation=1⁠

Trigger Warning: This episode talks about domestic violence and the warning signs of abusive relationships. If you or someone you know is experiencing domestic violence, support is available 24/7 through the National Domestic Violence Hotline.Call: 1-800-799-SAFE (7233)Text: START to 88788Website: https://www.thehotline.orgToday I'm joined by a fellow passenger of the Danny "hate" train since S1, @EchoDoesRadio to talk about the latest episode of The Valley. Echo was on my podcast a little less than a year ago discussing Danny's behavior on S2 and it was only fitting to bring her back for an update this season as other viewers are waking up to Danny's behavior. Indulge in a burrito, a sandwich, and 3 hours of you time locked away in your bedroom and enjoy this episode. For Nia. Follow Echo on Instagram: https://www.instagram.com/echodoesradio/Follow Echo on TikTok: https://www.tiktok.com/@echodoesradio?lang=enFollow Positively Uncensored on Instagram: https://www.instagram.com/positivelyuncensored/Follow Positively Uncensored on TikTok: https://www.tiktok.com/@positivelyuncensored?lang=enFollow Positively Uncensored on Threads: https://www.threads.com/@positivelyuncensored

On this week's show we do our annual Broadcast Network TV Renewals and Cancellations and also read your emails and look at the week's news. News: Fubo Lost Over 500,000 Subscribers in North America In The 2nd Quarter of 2026 AMC Theatres Partners With Arena One For Live Music Concert Streaming Other: Amazon.com: Panasonic Z8 Series (2025) 77-inch OLED 4K Ultra HD Smart Fire TV, Dolby Vision IQ, HDR10+ Adaptive, 144Hz Refresh Rate, Hands-Free Alexa 77Z8BAP Broadcast Network Renewals and Cancellations for the Next TV Season It's that time of year where we look at the fate of broadcast network TV Shows. The following list is based on the latest available info.  Note that The CW has largely shifted away from original scripted programming. ABC Strong stability for its drama and comedy slate. Renewed: 9-1-1 (S10), 9-1-1: Nashville (S2), Abbott Elementary (S6), Grey's Anatomy (S23), High Potential (S3), The Rookie (S9), Scrubs (revival, S2/overall S11), Shifting Gears (S3), Will Trent (S5). On the bubble: R.J. Decker (could go either way). Canceled/ending: Limited recent cancellations reported; some unscripted like The Bachelorette faced issues. CBS Very proactive with early renewals for its procedural-heavy lineup. Several new or recent shows got quick pickups. Renewed: Boston Blue (S2), CIA (S2), Elsbeth, FBI, Fire Country, Georgie & Mandy's First Marriage, Ghosts, Marshals (S2), Matlock, NCIS (S24), NCIS: Origins (S3), NCIS: Sydney, Sheriff Country (S2), Tracker  (S4), The Amazing Race, Survivor. Canceled/ending: DMV (after S1), Watson (after S2), TThe Neighborhood (final season, ending after S8). FOX Focus on animated comedies and a few live-action holds; some cancellations in the animated space. Renewed: American Dad! (through 2028-29), Animal Control (S5), Best Medicine  (S2), Bob's Burgers (through 2028-29), Doc (S3), Family Guy (through 2028-29), Krapopolis (through 2027-28), Memory of a Killer (S2), The Simpsons (through 2028-29), Universal Basic Guys, Grimsburg  (S3). Canceled/ending: The Great North, Going Dutch. On the bubble: Murder in a Small Town (safe bet). NBC The Chicago franchise remains rock-solid; some newer shows didn't make it. Renewed: Chicago Fire, Chicago Med, Chicago P.D., Happy's Place (S3), St. Denis Medical (S3),  Law & Order: SVU (S28), The Fall and Rise of Reggie Dinkins (S2). Canceled/ending: Brilliant Minds, Stumble. On the bubble: Law & Order (safe bet), The Hunting Party (long-shot). The CW Mostly wrapping up remaining originals. Ending: All American (S8 is final season). Canceled: Good Cop/Bad Cop (after S1). The network has minimized homegrown scripted shows in recent years.

What if loneliness isn't just an emotion… but one of the most dangerous biological threats to your health? In this deeply personal and scientifically explosive solo episode, Darin opens up about something he recently realized in his own life: despite being surrounded by people, he was lonely. But what began as an emotional realization quickly became a deep dive into some of the most shocking research he's ever uncovered, showing that chronic loneliness may increase the risk of heart disease, dementia, cancer, autoimmune dysfunction, accelerated aging, and early death. From inflammatory gene expression and cortisol dysregulation to oxytocin, vulnerability, and the collapse of real human connection in the digital age, this episode reveals why loneliness may be the most overlooked "fatal convenience" of modern life, and how vulnerability may be the medicine. What You'll Learn Why loneliness is a biological crisis, not just an emotional feeling The shocking link between loneliness and heart disease, dementia, and early death Why the quality of your relationships is the #1 predictor of long-term health How loneliness activates inflammatory genes inside your body The role of cortisol, sleep disruption, and chronic stress in social isolation Why social media and "surface-level connection" are replacing real intimacy The connection between loneliness and Alzheimer's disease How oxytocin and genuine connection reduce inflammation Why vulnerability is the gateway to meaningful relationships Practical ways to create deeper connection starting today Chapters 00:00:33 – Sponsor: the truth about the exploding NAD supplement market 00:01:04 – Why supplement verification and transparency matter 00:02:17 – Opening: Darin admits something deeply personal 00:02:30 – "I realized recently… I'm lonely" 00:02:37 – The difference between being surrounded by people vs being truly known 00:03:06 – Loneliness as a biological experience, not just an emotional one 00:03:27 – The hidden risks: heart disease, dementia, cancer, early death 00:03:45 – Why this is not fringe science 00:04:13 – The most important predictor of long-term health 00:04:34 – Why relationship QUALITY matters more than quantity 00:05:06 – The global loneliness epidemic 00:05:11 – U.S. Surgeon General advisory on loneliness 00:05:39 – Loneliness declared a public health crisis 00:06:02 – 50% of Americans report measurable loneliness 00:06:22 – "A generational collapse of connection" 00:06:30 – 29% of adults have no close friends 00:06:40 – Face-to-face interactions dramatically declining 00:07:01 – The UK, Japan, and Australia loneliness crisis initiatives 00:07:32 – The paradox: hyperconnected but deeply isolated 00:08:04 – Loneliness as a biological alarm signal 00:08:31 – What loneliness actually looks like in modern life 00:08:42 – The lonely CEO, the unseen mother, the isolated social media addict 00:09:31 – "Perceived social isolation" and why the brain can't tell the difference 00:10:21 – Meta-analysis of 3.4 million people 00:10:55 – Loneliness vs obesity and smoking risk comparisons 00:11:18 – The biology of loneliness begins 00:11:50 – NF-kB: inflammatory gene activation explained 00:12:33 – How loneliness changes gene expression 00:13:02 – Chronic inflammation and disease pathways 00:13:21 – Cortisol, sleep disruption, and immune dysfunction 00:14:00 – How loneliness affects brain repair and amyloid plaque clearing 00:14:21 – Sponsor: Fatty15 and cellular health 00:18:02 – The Alzheimer's and dementia connection 00:18:25 – Loneliness as a major modifiable dementia risk factor 00:18:57 – Cortisol, neuroinflammation, and brain degeneration 00:19:16 – The hippocampus physically shrinking in lonely people 00:19:27 – Social media as a "fatal convenience" 00:19:57 – The oxytocin economy: connection as medicine 00:20:15 – Oxytocin as one of the body's strongest anti-inflammatory molecules 00:20:30 – HeartMath research: emotional synchronization between people 00:20:48 – "You regulate each other's biology" 00:21:07 – The real barrier: vulnerability 00:21:32 – Darin's recent experiences with radical vulnerability 00:21:54 – Conversations with family, ex-partners, and loved ones 00:22:35 – Brené Brown's research on connection and worthiness 00:23:14 – The "depth audit" exercise 00:23:42 – Reaching out, expressing appreciation, and owning your emotions 00:24:01 – Sacred hours: spending time without phones 00:24:13 – Questions that create real intimacy 00:24:30 – Darin's emotional conversation with his brother 00:25:03 – Protecting yourself from social media disconnection 00:25:20 – Becoming a source of joy and connection in everyday life 00:25:25 – Darin reflects on seven years of subtle loneliness 00:25:48 – The shift from surface conversations to meaningful connection 00:26:01 – "If you want love, give love" 00:26:19 – Final message: generate the connection you want to receive 00:26:22 – Closing thoughts and outro Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Loneliness isn't weakness. It isn't failure. It's a biological signal telling you that something essential is missing. And in a world addicted to surface-level connection, the real medicine may simply be this: vulnerability, presence, eye contact, honesty, and the courage to let yourself truly be seen." Bibliography/Sources The Loneliness Epidemic & Public Health Data Bureau of Labor Statistics. (2023). American time use survey. U.S. Department of Labor. https://www.bls.gov/tus/ Cigna. (2023). Cigna U.S. loneliness index. Evernorth Health Services. https://newsroom.cigna.com/loneliness-epidemic-continues-to-rise-cigna-study Murthy, V. H. (2023). Our epidemic of loneliness and isolation: The U.S. Surgeon General's advisory on the healing effects of social connection and community. U.S. Department of Health and Human Services. https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf Survey Center on American Life. (2021). The state of American friendship: Change, challenges, and loss. American Enterprise Institute. https://www.americansurveycenter.org/research/the-state-of-american-friendship-change-challenges-and-loss/ Mortality & Systemic Health Risk Cohen, S., Doyle, W. J., Skoner, D. P., Rabin, B. S., & Gwaltney, J. M. (1997). Social ties and susceptibility to the common cold. JAMA, 277(24), 1940–1944. https://pubmed.ncbi.nlm.nih.gov/9200634/ Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://pubmed.ncbi.nlm.nih.gov/20396846/ Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 Valtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke. Heart, 102(13), 1009–1016. https://heart.bmj.com/content/102/13/1009 Genetics, Inflammation & The Immune System Cole, S. W. (2013). Social regulation of human gene expression: Mechanisms and implications for public health. American Journal of Public Health, 103(S1), S84–S92. https://pmc.ncbi.nlm.nih.gov/articles/PMC3786756/ Cole, S. W., Hawkley, L. C., Arevalo, J. M. G., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007). Social regulation of gene expression in human leukocytes. Genome Biology, 8(9), Article R189. https://pmc.ncbi.nlm.nih.gov/articles/PMC2375027/ Sleep & Cognitive Decline Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., Ernst, J. M., Gibbs, A. C., Stickgold, R., & Hobson, J. A. (2002). Do lonely days invade the nights? Potential social modulation of sleep efficiency. Psychological Science, 13(4), 384–387. https://pubmed.ncbi.nlm.nih.gov/12137144/ Holwerda, T. J., Deeg, D. J. H., Beekman, A. T. F., et al. (2014). Feelings of loneliness, but not social isolation, predict dementia onset. Journal of Neurology, Neurosurgery & Psychiatry, 85(2), 135–142. https://jnnp.bmj.com/content/85/2/135 Oxytocin & The Biology of Connection Szeto, A., Sun-Suslow, N., Mendez, A. J., Hernandez, R. I., Wagner, K. V., & McCabe, P. M. (2017). Regulation of the macrophage oxytocin receptor in response to inflammation. American Journal of Physiology—Endocrinology and Metabolism, 312(2), E183–E189. https://journals.physiology.org/doi/full/10.1152/ajpendo.00424.2016 Uvnas-Moberg, K. (2003). The oxytocin factor: Tapping the hormone of calm, love, and healing. Da Capo Press. https://books.google.com/books?id=b-aKjQoB_nQC Psychology, Vulnerability & Relationship Science Aron, A., Melinat, E., Aron, E. N., Vallone, R. D., & Bator, R. J. (1997). The experimental generation of interpersonal closeness. Personality and Social Psychology Bulletin, 23(4), 363–377. https://doi.org/10.1177/0146167297234003 Brown, B. (2010). The gifts of imperfection: Let go of who you think you're supposed to be and embrace who you are. Hazelden Publishing. https://brenebrown.com/book/the-gifts-of-imperfection/ Cacioppo, J. T., & Patrick, W. (2008). Loneliness: Human nature and the need for social connection. W. W. Norton & Company. https://wwnorton.com/books/9780393335286 Dunbar, R. I. M. (2012). Bridging evolutionary approaches to the social brain and social bonding. In F. B. M. de Waal & P. F. Ferrari (Eds.), The primate mind. Harvard University Press. https://www.hup.harvard.edu/books/9780674063104 Dunbar, R. I. M. (2021). Friends: Understanding the power of our most important relationships. Little, Brown and Company. https://www.hachettebookgroup.com/titles/robin-dunbar/friends/9781408711736/ Waldinger, R., & Schulz, M. (2023). The good life: Lessons from the world's longest scientific study on happiness. Simon & Schuster. https://www.simonandschuster.com/books/The-Good-Life/Robert-Waldinger/9781982166694