Podcasts about Adherence

It's In the News, a look at the top headlines and stories in the diabetes community. This week's top stories: Stem Cell Islet Therapy Partnership, "Lyla's Law" Type 1 Testing Debate, Patient-Led Insulin Dosing for Gestational Diabetes, $3 Semaglutide Manufacturing, FDA GLP-1 Compounding Crackdown Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  transcript with links:  Welcome! I'm your host Stacey Simms and this is an In The News episode.. where we bringing you the top diabetes stories and headlines happening now. A reminder that you can find the sources and links and a transcript and more info for every story mentioned here in the show notes. I am definitely feeling better – that lingering cold is gone – but whew still recovering from non stop travel for the past five weeks. I have a great strech of time her at home, then going to Vegas for Brekathorugh T1D at the end of the month and we have two club 1921 events in April – Atlanta and Philly. Before we jump into the news – I need your community commercials! These have been a lot of fun, I announced them late last year – your voice on the show. All the instructions it's very easy in the show notes. Okay.. our top story this week: XX A biotech company developing stem-cell treatments for type 1 diabetes has announced a new research partnership aimed at improving the survival of transplanted insulin-producing cells. NewcelX, a clinical-stage company based in Switzerland, said it will work with Eledon Pharmaceuticals to study a combination approach. The goal is to help transplanted cells survive longer in the body by reducing the immune response that often leads to transplant rejection. If successful, the strategy could support longer-lasting islet cell replacement and move the therapy closer to becoming a functional treatment for people with type 1 diabetes. However, the companies have not yet released any safety or effectiveness data on the combination treatment, and financial details of the partnership were not disclosed. The research agreement is focused on exploring whether combining stem-cell-derived islets with targeted immune therapy can lead to longer-lasting cell transplants and improved outcomes for people with type 1 diabetes. https://www.stocktitan.net/news/ELDN/newcel-x-announces-strategic-collaboration-with-eledon-d10l1vqdofls.html XX Debate this week in the UK on whether testing for type 1 diabetes should become mandatory when children present with symptoms. The Westminster Hall debate, scheduled for 9 March, will consider calls for routine testing of babies, toddlers and young children who show signs associated with the condition. It follows a petition backing the move, dubbed 'Lyla's Law', which passed 121,000 signatures in December 2025. The campaign was launched by John Story after his two-year-old daughter, Lyla, died from diabetic ketoacidosis (DKA) on 3 May 2025, 16 hours after being diagnosed with tonsillitis. https://www.nursinginpractice.com/clinical/diabetes-and-endocrinology/diabetes-community-urged-to-call-on-mps-to-attend-lylas-law-debate/ XX     A new study suggests that people with gestational diabetes who adjust their own insulin doses may reach healthy blood sugar levels faster than those whose doses are adjusted by clinicians. Half of the participants were assigned to adjust their own insulin doses using a simple rule: increase the dose by two units if fasting blood glucose was above 95 mg/dL, decrease it by two units if it dropped below 70 mg/dL, and keep the same dose if levels fell in between. The other half had their insulin adjusted by clinicians through weekly reviews. By the end of pregnancy, both groups had similar average fasting glucose levels before delivery: about 89 mg/dL in the patient-led group and 90 mg/dL in the clinician-led group. However, those adjusting their own insulin reached their blood sugar targets more quickly, averaging 1.8 weeks compared with 2.5 weeks for those managed by clinicians. The study also found lower risks of certain complications among the patient-led group. https://www.medscape.com/viewarticle/self-insulin-dosing-leads-control-gestational-diabetes-2026a1000729 XX   A blockbuster anti-obesity and diabetes drug could cost as little as $3 per month to manufacture once it goes off patent later this month, researchers said Friday, providing a major opportunity to boost health in low and middle-income countries.   Semaglutide, the active molecule in Novo Nordisk's Ozempic and Wegovy will lose patent protection in countries such as Brazil, China, and India later this month, and researchers identified 150 countries where it was never patented. These researchers estimated it will cost as little as $3 to produce a month's supply of semaglutide, which in its branded form sells for around $200 a month in the United States. Another of the study's authors, Professor Francois Venter at the University of Witwatersrand in South Africa, said drugs to treat HIV, TB, malaria, and hepatitis are now available at prices close to production costs but still sufficient for generic manufacturers to operate. https://www.sciencealert.com/weight-loss-drugs-could-cost-just-3-a-month-to-make-as-patents-end XX Here in the US the FDA is stepping up its efforts to combat widespread GLP-1 drug compounding. In its latest offensive, the agency has unleashed a fresh set of 30 warning letters targeting telehealth companies it says make "false or misleading" claims about compounded versions of popular obesity drugs. The FDA says Compounded drugs can be important for overcoming shortages or meeting unique patient needs—but compounders should not try to compound drugs in a way that circumvents FDA's approval process." https://www.fiercepharma.com/pharma/fda-ramps-crackdown-glp-1-drug-compounders-fresh-batch-30-warning-letters XX   Check your infusion sets for an issue: Unomedical, a subsidiary of Convatec and a supplier of insulin infusion sets to diabetes tech firms, has received a warning letter from the FDA. Inspectors raised concerns with leaking infusion sets, following a regulatory assessment of Unomedical's facility in Reynosa, Mexico, last summer. Unomedical supplies infusion sets to insulin pump makers including Medtronic, Tandem Diabetes Care and Beta Bionics. In a Feb. 3 statement, Convatec said the letter focuses on reporting procedures and quality protocols and does not place restrictions on producing, marketing or distributing any of Unomedical's products.  Unomedical told the FDA in its responses that it plans to conduct a retrospective review of complaints involving serious injury or death by January and conduct additional training on complaint handling by May.   https://www.medtechdive.com/news/fda-warns-insulin-infusion-set-maker-unomedical-over-leaks-mishandled-comp/813503/ XX Nearly four in ten people with type 2 diabetes do not take their medications as prescribed, according to a new research review published in Diabetologia in November 2025.   Researchers examined existing studies on medication adherence, including how often patients miss doses, why it happens, and what strategies may help. They estimated that about 38% of patients with type 2 diabetes are not fully adherent to their medications.   Adherence rates vary depending on the type of medication. About 63% to 68% of patients take oral glucose-lowering drugs as directed, while adherence drops to 43% to 54% for injectable GLP-1 medications and 41% to 64% for insulin.   Poor adherence can lead to serious consequences. One retrospective study cited in the review found that patients who consistently took their glucose-lowering medications had a 31% lower risk of hospitalization or emergency department visits.   The review also highlighted ways to improve adherence. Simplifying medication routines can help, such as using fixed-dose combination pills, which combine multiple drugs into a single tablet. Studies show these combinations are linked to better adherence and improved blood sugar control.   Pharmacists can also play an important role by providing education, reviewing medications, setting up reminders, and helping patients organize their treatment plans. The researchers noted that support should be tailored to each patient. Older adults may benefit from simpler systems and caregiver support, while younger patients may respond better to digital tools like app-based reminders.   The authors also found that measuring adherence is challenging and recommend using multiple methods, such as pharmacy records, patient interviews, and objective tests when possible.   Overall, the review concludes that personalized, multi-step approaches lasting at least three months are most effective in helping people with type 2 diabetes stay on track with their medications. https://www.pharmacytimes.com/view/type-2-diabetes-medication-adherence-rates-remain-low-and-pharmacists-can-help XX New clinical trial shows metformin does not directly reverse insulin resistance in people with type 1 diabetes. Instead, it lowers the total amount of insulin required to keep blood glucose levels within the recommended range. The findings, published in Nature Communications, challenge long-held assumptions about how metformin works in type 1 diabetes. The results may help physicians refine treatment strategies and reduce the daily demands placed on people who rely solely on insulin therapy. "Insulin resistance is a growing problem in type 1 diabetes. Not only does it make regulating blood sugar levels difficult, but it is an underappreciated risk factor for heart disease, which is one of the biggest causes of health complications and deaths in those with type 1 diabetes," says Dr. Jennifer Snaith, endocrinologist and co-lead of the study.   https://scitechdaily.com/groundbreaking-trial-reveals-unexpected-benefit-of-metformin-in-type-1-diabetes/   Tech news ahead, including updates from Sensonics, Dexcom & Tandem.. right after this…. Back ot the wnews.. XX Sensonics shares that it's secured FDA investigational device exemption (IDE) for its self-powered, battery-enabled Gemini sensor. It enrolled the first patients in the IDE trial and expects to complete that in the second half of 2026. Gemini builds on the implanted CGM to put the transmitter under the skin as well as the sensor. https://www.drugdeliverybusiness.com/senseonics-q4-2025-ide-gemini-cgm/ XX Medtronic Diabetes is now officially MiniMid, a stand alone public company. Medtronic  acquired MiniMed 25 years ago announed last May that it would spin its diabetes business off. In their statement the company points out that MiniMed is the only diabetes tech company to sell both insulin pumps and continuous glucose monitors.   https://www.investing.com/news/stock-market-news/medtronics-diabetes-unit-minimed-valued-at-53-billion-as-shares-fall-in-nasdaq-debut-4547518 XX Kevin Sayer heads back to Dexcom.. The former CEO is back in his position as executive chair of the Board, he'd stepped away for a medical leave. Dexcom (Nasdaq:DXCM) announced today in an SEC filing that former CEO Kevin Sayer has returned from his leave of absence. Sayer's return to the board comes just days after Dexcom announced a new board member. Last week, the company announced that it added Google SVP, Platforms and Devices, Rick Osterloh, to its board as well.     https://www.drugdeliverybusiness.com/kevin-sayer-returns-dexcom-board-chair/ SAN DIEGO - DexCom, Inc. (NASDAQ:DXCM) announced the appointment of Rick Osterloh to its Board of Directors, effective today, according to a press release statement.   Osterloh serves as Senior Vice President, Platforms & Devices at Google, where he oversees Android, Google Play, Chrome, and Google's hardware portfolio including Pixel phones, Google Nest devices, and Fitbit wearables. He has held this position since 2016.   https://www.investing.com/news/company-news/dexcom-appoints-google-executive-rick-osterloh-to-board-93CH-4529662 XX Sequel Med Tech announced broad national availability of its twiist™ Automated Insulin Delivery (AID) System powered by Tidepool. After U.S. FDA clearance in 2024 and a controlled launch to optimize the twiist experience, the system is now fully available nationwide. The release says: Built on Sequel's proprietary iiSure™ Technology, the system enables earlier detection of delivery issues, alerting users to blockages up to nine times faster than other AID systems1, potentially reducing the risk of unexplained high glucose and giving you time to take action before experiencing severe high blood sugar or DKA2. Designed to expand access to automated insulin delivery, twiist is available through pharmacy channels with a flexible access model, XX Tandem Diabetes Care's Mobi automated insulin delivery system is now available with Android devices. In November, Tandem announced that it received FDA approval for the Android version of its Mobi mobile app. The pump, which pairs with Tandem's Control-IQ+ algorithm, previously worked with iOS software. At the time of the clearance, it said it would commence a limited rollout before the full launch — now underway — this year.   Tandem launched Mobi in the U.S. in February 2024. It initially received FDA clearance for people with diabetes ages six and up in July 2023. The system then received expanded clearance for pediatric indications in April 2024, then later won CE mark in May 2025.   Mobi features a 200-unit insulin cartridge and an on-pump button to provide an alternative to phone control for insulin boluses. It comes in at less than half the size of the flagship Tandem pump system, the t:slim X2 pump. Mobi can fit in a coin pocket, clip to clothing or go on the body with an adhesive sleeve. https://www.drugdeliverybusiness.com/tandem-diabetes-care-launches-mobi-android/

In this episode:Unlock the secrets to transforming therapy sessions with the most nuanced questioning strategies—discover how the power of inquiry can deepen connection, boost treatment adherence, and unveil true insights. If you're a therapist, student, or mental health enthusiast craving a fresh perspective on clinical questioning, this episode is your gateway to mastering the art of all-important conversations that truly matter.and relational questions—showing you how to craft inquiries that foster self-discovery instead of defensiveness. In this revealing episode, you'll learn how the small shifts in phrasing can dramatically influence the therapeutic bond and outcome. 7 probing questions of guest Byron Athene Here are seven Probable probing questions GB ask Byron Athene to delve deeper into his insights and experiences:How do you integrate the Socratic method into your therapy sessions, and what impact have you observed on client outcomes?Can you share an example where a shift from a "why" question to a more open-ended inquiry significantly changed the direction of a therapy session?In your experience, how do declarative questions influence the power dynamics between therapist and client, and how can they be used to enhance treatment adherence?What are some common pitfalls therapists face when attempting to map systemic patterns through circular questioning, and how can they avoid these traps?How do you balance the need for diagnostic precision with maintaining a natural conversational flow in therapy sessions?Can you discuss the role of silence in your therapeutic practice and how it contributes to building trust and facilitating client breakthroughs?What advice would you give to new therapists about the art of questioning, particularly in avoiding common mistakes that might hinder client progress?These questions are designed to explore Byron Athene's methodologies and insights, providing valuable perspectives for both seasoned and aspiring therapists.Unlock the secrets of effective therapeutic questioning with Grandpa Bill as he dissects the nuanced art of inquiry in psychotherapy and psychiatry. Did you know that overusing questions can inadvertently lower a client's perception of empathy — and that shifting from interrogative to declarative statements can dramatically boost treatment adherence? If you're a mental health professional, student, or even a curious layperson, this episode will transform how you understand the power of words in healing.Grandpa Bill dives deep into the subtle balance between Socratic questioning, guided discovery, and leading clients toward genuine insights — without turning the session into an interrogation. You'll discover research-backed strategies like using declarative statements to foster trust, circular questioning to map systemic patterns, and how silence and unasked questions influence the therapeutic alliance. Plus, get a firsthand look at common pitfalls like the “why trap” that can trigger defensiveness or intellectualization, and practical tips to avoid them.Questions-What Say You:How can shifting from interrogative to declarative statements boost treatment adherence?

In today's episode I talk about some of the reason's why people struggle with the long term consistency and adherence in the physique game and what to do to change that and stay consistent long term to get results. 

In episode 242, Coffey talks with Lee Colan about rebuilding human connection in a technology-driven, hybrid workplace.  They discuss the loneliness epidemic and its impact on employee wellbeing; differences between social isolation and emotional loneliness; remote work and the rise of frictionless digital experiences; Gallup and BetterUp data on workplace friendships and retention; the decline of socializing with coworkers outside work; practical rituals like high-low check-ins during meetings; the cultural effects of hybrid work and hot desking; personalization of workspaces to reinforce belonging; AI disruption of career paths and entry-level roles; the growing value of human-centered leadership skills; and a four-step model for building meaningful professional relationships.  Lee Colan's next book “The Connection Key: How to Unlock Your Positive Impact and Enhanced Wellbeing” releases in September.  For HR teams who discuss this podcast in their team meetings, we've created a discussion starter PDF to help guide your conversation. Download it here https://goodmorninghr.com/EP242  Good Morning, HR is brought to you by Imperative—Bulletproof Background Checks. For more information about our commitment to quality and excellent customer service, visit us at https://imperativeinfo.com.   If you are an HRCI or SHRM-certified professional, this episode of Good Morning, HR has been pre-approved for half a recertification credit. To obtain the recertification information for this episode, visit https://goodmorninghr.com.   About our Guest:  Lee J. Colan, Ph.D. is Lee is an organizational psychologist and CEO advisor. He possesses a rare combination of skills as a corporate executive, business consultant, thought leader, prolific author, artful facilitator, and engaging presenter.   Lee applies an in-depth understanding of business, science, people, and organizations to help leaders and organizations grow. As a result, he quickly helps leaders bring order where there is chaos, clarity where there is ambiguity and growth where there is decline. Lee is a John C. Maxwell Leadership Award finalist and Thinkers50 nominee for Top Management Thinker globally.  He has authored 16 popular leadership books that have been translated into 10 languages, including the bestselling Engaging the Hearts and Minds of All Your Employees, Stick with It: Mastering the Art of Adherence and Healthy Leadership. He has also created over 50 products that equip and encourage leaders at every level. Expertise CEO advisement, executive coaching, strategy planning and execution, employee engagement, keynote speaking, leadership training.  Education Doctoral degree, Organizational Psychology, George Washington University Bachelor's degree, Psychology and Communications, Summa Cum Laude, Florida State University Background  Lee brings 25 years of hands-on industry and consulting experience to his clients. He worked in various leadership roles with American Airlines, Sandoz (Novartis) and FoxMeyer (McKesson). He also held consulting positions with two premier firms: Booz, Allen & Hamilton and Mercer. His last corporate post was as Vice President for Physician Reliance Network (U.S. Oncology), one of the fastest growing NASDAQ companies at the time.  Lee currently serves as an Independent Director and member of the Personnel Committee for Pacific Seafood Group, the largest vertically integrated seafood company in North America. He is a former director for Aztec Systems who was ultimately sold to a private equity firm. He also served on the Advisory Board for ASSET InterTech who was acquired in 2021 by Constellation Software.  Lee Colan can be reached at https://thelgroup.com https://www.linkedin.com/in/leecolan  https://www.facebook.com/TheLGroupInc  https://www.instagram.com/leecolan  https://www.youtube.com/user/LeeJColan  About Mike Coffey:  Mike Coffey is an entrepreneur, licensed private investigator, business strategist, HR consultant, and registered yoga teacher. In 1999, he founded Imperative, a background investigations and due diligence firm helping risk-averse clients make well-informed decisions about the people they involve in their business. Imperative delivers in-depth employment background investigations, know-your-customer and anti-money laundering compliance, and due diligence investigations to more than 300 risk-averse corporate clients across the US, and, through its PFC Caregiver & Household Screening brand, many more private estates, family offices, and personal service agencies. Imperative has been named a Best Places to Work, the Texas Association of Business' small business of the year, and is accredited by the Professional Background Screening Association.  Mike shares his insight from 25+ years of HR-entrepreneurship on the Good Morning, HR podcast, where each week he talks to business leaders about bringing people together to create value for customers, shareholders, and community. Mike has been recognized as an Entrepreneur of Excellence by FW, Inc. and has twice been recognized as the North Texas HR Professional of the Year.  Mike serves as a board member of a number of organizations, including the Texas State Council, where he serves Texas' 31 SHRM chapters as State Director-Elect; Workforce Solutions for Tarrant County; the Texas Association of Business; and the Fort Worth Chamber of Commerce, where he is chair of the Talent Committee. Mike is a certified Senior Professional in Human Resources (SPHR) through the HR Certification Institute and a SHRM Senior Certified Professional (SHRM-SCP). He is also a Yoga Alliance registered yoga teacher (RYT-200) and teaches multiple times each week. Mike and his very patient wife of 29 years are empty nesters in Fort Worth.   Learning Objectives: Identify the business impact of workplace loneliness and disconnection. Apply a simple four-step model to strengthen team relationships. Embed connection-building rituals into meetings and daily leadership practices. 

The Middle East is on edge after US and Israeli strikes killed Iran's Supreme Leader, Ali Khamenei. It triggered retaliatory missile attacks, emergency U.N. meetings and protests across several countries. World leaders are divided, while civilians across the region brace for further escalation. Sakina Kamwendo spoke to Associate Professor of Public International Law, at the University of Johannesburg (UJ) Professor Sikwani Ncube

Are you optimizing inhaler choice and technique to achieve better outcomes? Credit available for this activity expires: 2/27/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/prescription-practice-respiratory-diseases-overcoming-2026a100058h?ecd=bdc_podcast_libsyn_mscpedu

An interview with Alantheus Thompson, Groe SolutionsSo the members benefit from having that layer of accountability if they are working with a trainer. And if not just more broadly, the gyms, being able to know what they're doing and when they are going to get a new piece of equipment that aligns with them, or they're going to implement a new training program instead of getting them bombarded with a marketing campaign that doesn't apply to them, you can get really specific, and you're more likely to get aligned to the people that you care about.Alantheus ThompsonGroe Solutions origin storyAddressing club operator pain pointsValue for club operators, fitness professionals and membersBoosting member retention with adherence, accountability and communityGroe Solutions' ultimate visionUsing verified activity to expand accessibilityTracking adherence and progression dataReturn on investment for fitness programmingEntrepreneurship in the fitness industrySolving the member retention problemSupporting behavior change Increasing accessibility with technologyhttps://www.movetolivemore.com/https://www.movetolivemore.com/bookhttps://www.linkedin.com/company/move-to-live-more@MovetoLiveMore 

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In this episode, Jacob and Coach Blake dive into one of the biggest challenges in coaching—adherence. They break down what adherence really means, why clients struggle to stick to plans, and how coaches can respond when things go off track. From under-reporting food intake to handling clients who never start (or stop following) their plan, this episode is packed with practical tools and strategies to improve consistency and results.

Episode 213: HIV PrEP Review H. Nicole Magaña, medical student, reviews the history of PrEP and outlines the currently FDA-approved medications used for HIV prevention. Dr. Arreaza provides additional perspective on long-acting injectable options, including how quickly they begin to protect patients after initiation.   Written by Nicole Magana, MSIV, American University of the Caribbean. Comments and edits by Hector Arreaza, MD. You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice. Pre-exposure prophylaxis for HIV. Previous episodes related to HIV:  -Episode 67, HIV history (September 2021) -Episode 68, HIV transmissibility (October 2021) -Episode 70 (October 2021), HIV prevention (including HIV Prep with oral medications) -Episode 98 (June 2022), we introduced Apretude, the first injectable for HIV PrEP. Apretude was approved in December 2021.  What is Pre-Exposure prophylaxis (PrEP)? Pre-exposure prophylaxis, or PrEP, is the use of antiretroviral medications taken by individuals who are HIV-negative to prevent HIV acquisition. There are 30,000 new HIV infections annually in the US.  How effective is it? When taken as prescribed, PrEP is highly effective at reducing the risk of HIV transmission through sexual exposure and injection drug use. Patients who are adherent to PrEP can lower their risk of contracting HIV by 99%. The effectiveness of oral PrEP is highly adherence dependent. In trials with 70% adherence, the relative risk of HIV acquisition was 0.27, compared to 0.51 with 40-70% adherence and no significant benefit with adherence ≤40%. How does PrEP work? PrEP works by maintaining therapeutic drug levels in the bloodstream and in target tissues. If HIV exposure occurs, viral replication is inhibited, preventing the establishment of infection. Brief History of PrEP. The concept of PrEP originated from early animal studies demonstrating that antiretroviral medications could prevent retroviral transmission when administered before exposure. In 2010, the iPrEx trial showed that daily oral tenofovir disoproxil fumarate (known as Truvada) with emtricitabine significantly reduced HIV acquisition among men who have sex with men and transgender women. This was the first large clinical trial to demonstrate the effectiveness of PrEP. In 2012, the FDA approved oral Truvada, which is TDF/FTC (tenofovir disoproxil and emtricitabine) for HIV prevention. Since then, additional studies have expanded indications and introduced new formulations, including long-acting injectable options. Who Should Be Offered PrEP? PrEP should be considered for any HIV-negative individual at increased risk of HIV acquisition, including Men who have sex with men, transgender individuals, heterosexual men and women with an HIV-positive partner, individuals with recent bacterial sexually transmitted infections, people who inject drugs, individuals engaging in condomless sex with partners of unknown HIV status. Remember that PrEP should be offered in a nonjudgmental, patient-centered manner, make it a safe space to talk openly about prevention of HIV.  Available HIV PrEP Options. Daily Oral PrEP: There are 2 formulations of Tenofovir. There is Tenofovir disoproxil fumarate (TDF)/ Truvada and Tenofovir alafenamide (TAF)/ Descovy. Each is available in a tablet combined with Emtricitabine a nucleoside reverse transcriptase inhibitor. Truvada: It is approved for all populations at risk through sexual exposure or injection drug use. Something to look out for before starting this medication is for pre-existing CKD. Do not give to patients who have an estimated glomerular filtration rate of less than 60 mL/min. (6) Descovy: This option is approved for men who have sex with men and transgender women but is not approved for individuals at risk through receptive vaginal sex. It has less impact on renal function and bone mineral density compared to Truvada. It can be used in moderately reduced kidney function (GFR between 30-60 mL/min). Truvada and Descovy are taken orally once a day.  After patients start taking these medications, when are they considered to be protected?  Nicole: With daily oral PrEP, guidelines differ with WHO and International Aids Society-USA stating it takes about 7 days, while CDC states 21 days to allow for adequate concentration in tissues (1). Adherence is critical for efficacy. Injectable HIV PrEP. In 2021, the FDA approved the first Injectable PrEP option Long-acting cabotegravir (CAB-LA)- known on the market as Apretude. Cabotegravir is an integrase strand transfer inhibitor administered as an intramuscular injection.Dosing consists of an initial injection, a second injection one month later, and then maintenance injections every two months (1). Another option is Lenacapavir (Yeztugo). The Yeztugo as a pre-exposure prophylaxis (PrEP) for HIV in Oct 2024. Yeztugo is the first and only FDA-approved HIV prevention treatment that requires just two injections per year, offering a long-acting option for people who weigh at least 35kg. It is given as 2 injections every 6 months. First dose is given with 2 tablets on Day 1 and Day 2, then every 6 months 2 injections on the same day. Clinical trials, including HPTN 083 and HPTN 084, demonstrated that injectable cabotegravir is superior to daily oral PrEP in preventing HIV infection. This advantage is largely due to improved adherence rather than differences in intrinsic drug potency. There have been no head-to-head comparisons between Yeztugo and Apretude, but they are both very effective. Apretude starts protecting 7 days after the first dose, and Yeztugo starts protecting 2 hours after Day 2 (if patient takes the oral loading dose) or 3-4 weeks if no oral load is taken. Injectable PrEP is particularly beneficial for patients who struggle with daily pill adherence, have trouble swallowing pills, prefer a discreet option, have difficulty storing their medication or have renal or bone disease that limits the use of tenofovir-based regimens like Truvada and Descovy (6). In one unpublished report by Medline, patients who received Apretude had an increase in bone mineral density compared to those who received Truvada (1). Tests prior to starting PrEP. Before initiating PrEP, patients must be confirmed to be HIV-negative. Baseline evaluation includes HIV testing with a fourth-generation antigen/antibody assay, HIV RNA testing if acute infection is suspected, renal function testing for oral PrEP, Hepatitis B screening, sexually transmitted infection screening, and pregnancy testing when appropriate. PrEP should not be started in individuals with known or suspected acute HIV infection. Monitoring for patients on HIV PrEP. Monitoring typically includes HIV testing every 2 to 3 months, STI screening every 3 to 6 months, renal function monitoring for those on oral PrEP (tenofovir- based), ongoing adherence and risk-reduction counseling. And for injectable PrEP, adherence to the injection schedule is essential, as delayed dosing may increase the risk of resistance if HIV infection occurs. HIV PrEP is not a prevention for other STIs. Screening for STIs and counseling about prevention is essential. Breakthrough HIV infections on PrEP are rare and most often associated with poor adherence or delayed diagnosis. Truvada is more studied in all populations and is considered safe during pregnancy and breastfeeding. There is less data regarding the injectable option in patients who are pregnant, may become pregnant, or whose primary risk factor is injection drug use (1). Injectable PrEP provides an important alternative for patients with chronic kidney disease and bone disease (1). Key Takeaway Pre-exposure prophylaxis is a safe, effective, and evidence-based strategy for HIV prevention. With both daily oral and long-acting injectable options available, PrEP can be individualized to meet patient needs. Normalizing PrEP discussions in clinical practice is essential to reducing new HIV infections and advancing public health goals.  Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!  References: Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel. The Journal of the American Medical Association. 2025. Gandhi RT, Landovitz RJ, Sax PE, et al. Long-Acting Lenacapavir Acts as an Effective Preexposure Prophylaxis in a Rectal SHIV Challenge Macaque Model. The Journal of Clinical Investigation. 2023. Bekerman E, Yant SR, VanderVeen L, et al. Pharmacokinetics and Safety of Once-Yearly Lenacapavir: A Phase 1, Open-Label Study. Lancet. 2025. Jogiraju V, Pawar P, Yager J, et al.

We explore the FDA's expansion of Wakix as the first non-scheduled treatment for pediatric cataplexy; a Taltz and Zepbound combo shows promise in skin clearance for patients with psoriasis and obesity; we also look at the frontier of mental health with synthetic psilocybin; there's phase 3 results from a potential new treatment for chronic inducible hives; and a long-acting HIV injection could be a game-changer for patients who struggle with the daily pill grind.  

Shoulder and elbow injuries in pitchers are as old as baseball itself. Measures to lower the risk of these injuries have been evolving for decades, with a nationalized though heterogenous effort from state to state implemented in the mid-2010s. Adherence to pitch counts and mandatory days of rest in between outings, for example, are common restrictions placed upon pitchers to try and keep them safe. Dr. Peter Kriz, MD and his team from Boston Children's Hospital look back to see if these policies made any impact. Have the pitching restriction regulations designed to keep pitchers safe actually worked?

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Send a textLeitlinien sind ein zentrales Instrument der Qualitätssicherung in der Intensivmedizin – ihre konsequente Umsetzung im klinischen Alltag bleibt jedoch eine Herausforderung. In dieser Episode diskutieren wir eine multizentrische Studie aus Critical Care Medicine, die ein interoperables, automatisiertes System zur Überwachung der Leitlinienadhärenz auf Intensivstationen evaluiert.Lichtner G, Schiefenhövel F, Gashi B, et al.Multicenter Evaluation of an Interoperable System for Automated Guideline Adherence Monitoring in ICUs.Critical Care Medicine. 2026;54:119–128.DOI: 10.1097/CCM.0000000000006961Die Umsetzung evidenzbasierter Leitlinien auf Intensivstationen ist durch hohe klinische Komplexität, heterogene IT-Strukturen und inkonsistente Dokumentation limitiert. Manuelle Adhärenzprüfungen sind zeitaufwendig, fehleranfällig und kaum skalierbar. Ziel der vorliegenden multizentrischen Beobachtungsstudie war die Entwicklung, Validierung und Anwendung eines interoperablen Systems zur automatisierten Überwachung der Leitlinienadhärenz in der Intensivmedizin.In fünf universitären Zentren wurden retrospektiv über 82 000 Intensivaufenthalte (entsprechend mehr als 2,2 Millionen Patiententagen) analysiert. Sechs exemplarische Empfehlungen aus insgesamt 41 intensivmedizinischen Leitlinien wurden in ein standardisiertes, computerinterpretierbares Format überführt. Die Leitlinienrepräsentation erfolgte mittels HL7 FHIR, während klinische Routinedaten aus den Krankenhausinformationssystemen über das OMOP Common Data Model harmonisiert wurden. Für ausgewählte Zeiträume erfolgte zusätzlich eine manuelle Adhärenzbewertung durch erfahrene Intensivmediziner:innen, die als Referenz diente.Das automatisierte System identifizierte Anwendbarkeit und Adhärenz der Leitlinienempfehlungen mit einer Genauigkeit von 97 % und übertraf damit signifikant die manuelle Bewertung durch Ärzt:innen (86,6 %). Gleichzeitig zeigte sich ein massiver Effizienzgewinn: Während manuelle Reviews etwa 2 Patiententage pro Minute erlaubten, verarbeitete das System mehr als 2000 Patiententage pro Sekunde. Die Analyse offenbarte erhebliche Unterschiede in der Leitlinienadhärenz zwischen Zentren, Empfehlungen und Zeitverläufen, wobei Dokumentationsqualität, sich wandelnde Evidenz (z. B. während der COVID-19-Pandemie) und unpräzise formulierte Empfehlungen zentrale Einflussfaktoren waren.Die Studie zeigt, dass interoperable, automatisierte Systeme eine hochskalierbare und valide Grundlage für kontinuierliche Qualitätsmessung in der Intensivmedizin bieten. Gleichzeitig unterstreichen die Ergebnisse die Notwendigkeit strukturierter Dokumentation und klar operationalisierbarer Leitlinien, um das volle Potenzial digitaler Qualitätsinstrumente auszuschöpfen.Heute im Studio: Jochen Gandowitz, wissenschaftlicher Mitarbeiter der Klinik für Anästhesiologie am UKHD

In this episode of Liver Lineup: Updates and Unfiltered Insights, hosts Kimberly Brown, MD, and Nancy Reau, MD, break down new research on liver transplantation, hepatocellular carcinoma (HCC), and the ongoing evolution of surveillance strategies in chronic liver disease. Drawing on their extensive experience as transplant hepatologists, Brown and Reau place new data into practical context, highlighting where evidence may meaningfully inform practice and where unanswered questions remain.Key episode timestamps:0:00:00 – Introduction0:00:19 – Frailty & Transplant Evaluation0:02:54 – How Centers Use Frailty Measures0:04:37 – Practicalities of the Six‑Minute Walk0:06:10 – MELD 3.0 and Sex/Size Disparities0:08:42 – Exception Points & Size Constraints0:10:05 – Need for a Dynamic MELD System0:10:19 – Immunotherapy as Bridge/Downstaging for HCC0:13:34 – Real‑World Use of IO Around Transplant0:15:22 – Managing Rejection Risk0:19:03 – MASLD Population & Surveillance Gaps0:20:21 – Adherence to HCC Surveillance0:22:42 – Practical Barriers: AFP, Ultrasound, Radiology Reports0:24:02 – Shift Toward Blood-Based Surveillance0:26:01 – How AFP-L3 and DCP Are Used in Practice0:27:39 – Rising AFP, Imaging Strategy & Broader Trend to Blood Tests0:28:27 – Guidelines vs Real-World Practice0:29:37 – Closing Thoughts on Guidelines & Early Detection

Adherence to oral antipsychotics is frequently disrupted by complex dosing schedules and side effects. This module examines the clinical benefits of long-acting injectables (LAIs), including steadier blood concentrations and improved patient tolerance. Learn how the latest LAI formulations can transform treatment adherence and long-term stability. After listening, be sure to move on to Module 3 to learn about emerging treatments for cognitive symptoms. Note: This podcast expires on 2/17. Click the link below to claim your CME/NCPD/CPE credit. https://bit.ly/436dYa5

Welcome to Hacking Your ADHD. I'm your host, William Curb. Today, I'm joined by Skye Waterson for our research recap series, where we dive into a single research paper to find practical takeaways. In this episode, we're discussing a paper called "Adherence, Persistence and Medication Discontinuation in Patients with Attention Deficit Hyperactivity Disorder: A Systematic Literature Review." This study asks: what's happening in the real world with medication adherence? Are people taking their meds, and if not, why? I found this paper through a presentation by Bill Dobson at the 2025 ADHD conference in Kansas City, and it really blew me away. If you'd life to follow along on the show notes page you can find that at https://HackingYourADHD.com/268 https://tinyurl.com/56rvt9fr - Unconventional Organisation Affiliate link https://tinyurl.com/y835cnrk - YouTube https://www.patreon.com/HackingYourADHD - Patreon

First detailed in 1972, clean intermittent catheterization has remained a cornerstone of urological care for more than half a century. Despite major advances in device design and materials, one challenge continues to stand out: ensuring patients can confidently and consistently adhere to the procedure.In this ICS Podcast episode, host Daniele Bianchi, urologist from Italy, explores the real‑world barriers to clean intermittent catheterization adherence. He speaks with Enrico Finazzi Agrò, urologist (Italy), and Angie Rantell, specialist nurse (UK), who share their clinical experience, insights, and practical suggestions for improving patient engagement and support. Together, they reveal what truly makes a difference for patients, and what the urology community can learn moving forward. Through its annual meeting and journal, the International Continence Society (ICS) has been advancing multidisciplinary continence research and education worldwide since 1971. Over 3,000 Urologists, Uro-gynaecologists, Physiotherapists, Nurses and Research Scientists make up ICS, a thriving society dedicated to incontinence and pelvic floor disorders. The Society is growing every day and welcomes you to join us. If you join today, you'll enjoy substantial discounts on ICS Annual Meeting registrations and free journal submissions. Joining ICS is like being welcomed into a big family. Get to know the members and become involved in a vibrant, supportive community of healthcare professionals, dedicated to making a real difference to the lives of people with incontinence.

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- Overview of Cancer Treatments - Definition of Adherence: Taking Your Pills on Schedule - Its Important Role in Managing Cancer - Barriers to Taking Your Pills - Practical Tips to Overcome These Barriers, Including Family, Partners & Others - Computer, Tablet & Phone Reminders Including Emails, Texts & Apps - Planning Ahead: Lead Time in Refilling Prescriptions, Weekends, Travel & Holidays - Communicating with Your Health Care Team about Adherence with Reminders from Your Pharmacy & Pharmacist - Clinical Trials on Adherence - The Increasing Role of Telehealth/Telemedicine Appointments - Guidelines to Prepare for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

In this episode of SleepTech Talk, we're joined by Aubrey Sawyer, President and Co-Founder, and Michelle Alencar, PhD, Chief Science Officer and Co-Founder of inHealth and CoachLinq, to discuss how developing better habits—especially in the new year—can transform sleep outcomes and improve adherence to PAP therapy.We dive into why PAP adherence is one of the biggest challenges in sleep medicine, and how coaching, behavior science, and data-driven approaches can help patients stick to therapy, maintain motivation, and achieve long-term success.Whether you're a sleep clinician, DME/HME professional, or someone personally using PAP therapy, this conversation offers practical insights into:Why patients struggle with PAP complianceHow habit formation impacts sleep and exerciseThe role of coaching in long-term adherenceUsing behavioral science to drive sustainable health outcomesHow sleep technology can support—not replace—human behavior change

In this episode, I explain what a real fat loss plateau actually is, whether plateaus are metabolic in nature, and how to use an adherence audit to break plateaus without drastic calorie cuts.   Chapters: 00:06 What Plateaus Really Are (and Aren't) 00:47 The Biggest Plateau Misconception 01:17 Motivation Dip vs Precision Dip 02:42 What a Real Plateau Actually Is 03:03 Why Weight Loss Is Not Linear 04:25 The Adherence Audit Framework 08:18 Hidden Variables That Stall Progress 10:27 Why You Shouldn't Rush Changes 13:51 When to Actually Adjust Calories or Activity 14:41 Adherence as a Long-Term Skill 16:48 Precision Reset and Final Framework 17:22 Final Thoughts and CTA   Next steps: 1) Book a 1-1 strategy session with my team to find out more: https://www.rntfitness.com/applynow  2) Take our free transformation quiz: https://www.rntfitness.com/transform 3) Rate your current health: https://scorecard.rntfitness.com/health    Follow RNT Fitness: Website - http://www.rntfitness.com LinkedIn - https://uk.linkedin.com/company/rnt-fitness Instagram - http://www.instagram.com/rnt_fitness   Follow Akash: LinkedIn - https://uk.linkedin.com/in/akash-vaghela  Instagram - http://www.instagram.com/akashvaghela  

Medication mismanagement is one of the most costly and preventable problems in healthcare as it impacts patient safety, outcomes, and billions in annual spending. In this episode, we're joined by Yoona Kim, who cofounded Arine to use AI-driven medication intelligence for improving patient outcomes. Join us in a conversation about the key factors that contribute to medication errors, why culturally sensitive care is central to Arine's approach, and how smarter use of data can shape future healthcare policy.Yoona Kim is the co-founder and CEO of the healthcare technology company Arine. After studying human biology at Stanford, she was trained as both a pharmacist (PharmD from the University of California San Francisco) and health economist (PhD from the University of Texas at Austin). She previously served as Vice President at Proteus Digital Health and held leadership positions in research and consulting at global pharmaceutical companies.

In this special edition on Adherence to Medications our host, Dr. Neil Skolnik will discuss medication adherence and the role of clinicians, pharmacies and pharmacists in helping with medication adherence. This special episode is supported by an independent educational grant from Amazon. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Susan Kuchera, M.D. - Clinical Assistant Professor of Family and Community Medicine at the Sidney Kimmel Medical College of Thomas Jefferson University and Program Director of the Family Medicine Residency at Jefferson Health Abington. Tess Carey, PharmD, Clinical Advisor for Amazon Pharmacy  Selected references: Better Medications Adherence Lowers Cardiovascular Events, Stroke, and All-Cause Mortality Risk: A Dose-Response Meta-Analysis. Journal of Cardiovascular Development and Disease. 2021, 8, 146. Adherence to antihypertensive medications for secondary prevention of cardiovascular disease events: a dose-response meta-analysis. Public Health 196 (2021) 179e185 Medication nonadherence - definition, measurement, prevalence, and causes: reflecting on the past 20 years and looking forwards. Frontiers in Pharmacology, March 2025. DOI 10.3389/fphar.2025.1465059  

Welcome to the Mind Muscle Connection Podcast!Peter Fitschen is back on the podcast for round four, and this one dives deep into Bodybuilding vs. Gen Pop Fat Loss Sustainability Thresholds, Reverse Dieting and More. We cover everything from smart prep timelines to post-diet recovery to why sustainability looks very different for competitors vs. lifestyle clients.We break down where most people go wrong in fat loss phases, how aggressive you can really be, plus Peter shares what he's doing differently now as a coach with over 100 pro cards under his belt and what that means for his own training and prep plans moving forward.This is a very interesting and insightful episode, so don't miss out!Let's talk about:Introduction to Peter FitschenUpdate on PeterFat lossBiofeedback, Adherence, and Gen Pop CoachingDiet quality & Meal timing in prepWhen to stop a fat loss phasePost-Show recovery & body fat set pointDifferent post-diet approaches for Gen PopPeter's training & nutritionPeter Fitschen's Instagram:https://www.instagram.com/fitbodyphysique/?hl=enPeter Fitschen's Website:https://fitbodyphysique.com/Follow me on Instagram for more information and education:  jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: https://chipper-producer-6244.kit.com/26b5c9f94a

In this research-driven episode, Dr. Scott Watier and Tommy Welling break down a comprehensive meta-analysis comparing multiple intermittent fasting protocols, revealing what actually works for sustainable weight loss and metabolic health improvement. They examine alternate day fasting, 5:2 fasting, and time-restricted eating, comparing outcomes for weight loss, cholesterol improvements, insulin resistance reduction, and long-term adherence rates. The hosts deliver crucial perspective on the trade-offs between aggressive protocols that produce faster results versus sustainable baseline approaches that support consistency through life's challenges. With the holiday season in full swing between Thanksgiving and Christmas, they provide a realistic framework for maintaining progress without perfectionism or all-or-nothing thinking. This episode helps you understand why chasing the fastest results often backfires, how to customize fasting protocols to match your lifestyle, and why taking the pressure off during the holidays—while maintaining a simple 16:8 baseline—can actually set you up for greater long-term success than aggressive restriction followed by complete abandonment of your fasting practice. ⁠⁠⁠⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Resources and Downloads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Partner Links: Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Our Community: Let's continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12309044/pdf/12937_2025_Article_1178.pdf

Chinese Foreign Minister Wang Yi says the one-China principle is the political foundation of China-Germany ties, and leaves no room for ambiguity. German Foreign Minister Johann Wadephul says Germany's commitment to the one-China principle will not change.

Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Yolanda D. McElroy (aka “Dr. Yo-Yo”).

Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Yolanda D. McElroy (aka “Dr. Yo-Yo”).

Two-time Emmy and three-time NAACP Image Award-winning television Executive Producer Rushion McDonald interviewed Dr. Yolanda D. McElroy (aka “Dr. Yo-Yo”).