Podcasts about Antifungal

Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis

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Best podcasts about Antifungal

Latest podcast episodes about Antifungal

Holistic Psychiatry Podcast
When Supplements (or Meds) Cause or Worsen Brain Symptoms

Holistic Psychiatry Podcast

Play Episode Listen Later Mar 21, 2025 14:32


Previously shared as a paid newsletter in May 2024. In previous newsletters, I've addressed many of the more common contributing factors to brain symptoms, including high pyrroles, copper-zinc imbalances, methylation imbalances, candida overgrowth, mast cell activation, mold and other forms of toxicity, and genetic variants, such as COMT and MAOA.Supplements can be needed to address each of these. Medication can also be necessary when treating mold and mast cell activation.But what happens when someone can't tolerate a supplement or medication because it worsens or creates new brain symptoms? Why, for example, could someone have problems tolerating B6 or SAMe or Methionine. Why might someone have problems with folate, niacinamide, glutathione, certain herbal treatments, antidepressants such as SSRIs, probiotics, antifungal medication or binders such as bentonite clay, activated charcoal, chlorella or cholestyramine?In this newsletter, I'll discuss:* Five common reasons a supplement or medication may worsen symptoms.* Specific supplements and medications that are more likely to do this.* How reactions may point to root causes.* Treatment steps that can improve tolerance.There can be a wide range of brain symptoms that can occur when someone is having an adverse reaction, such as fatigue, brain fog, depression, anxiety, agitation, and even psychosis or mania. I'll use “reactivity” to refer to this range of possibilities. While physical side effects can also occur, the focus here will be on brain symptoms.5 Common Reasons Supplements or Meds May Worsen Symptoms1. Immune ReactivityOur immune system is intertwined with our central nervous system. When our body's immune system reacts to a toxin, microbe, injury, or trauma, we can have inflammatory brain and physical symptoms.“Feel Like I'm Reacting to Everything” - Mast Cell ActivationIf someone is experiencing severe immune reactivity, such as mast cell activation, they may react to many supplements and medications, as well as triggers in their environment and stress. The number of triggers can help point to an exaggerated immune response. In my practice, this high immune reactivity is usually driven by mold toxicity.For many with this obstacle, starting very low and slow can prevent reactions. For others, interventions may be needed to lower immune reactivity and stabilize mast cells. This, however, can require certain supplements. For those who can't tolerate those treatments, limbic system retraining programs help calm the immune system so people can move forward more easily.Sensitivity & IntoleranceIt is possible to have immune sensitivity (or even allergy) to a supplement, though I find this less common. Herbal supplements, for example, which are high in salicylates, may cause symptoms in those with salicylate sensitivity. Certain probiotics have bacterial strains high in histamine. This is an issue for those with histamine intolerance.2. Too Much or Too Little Neurotransmitter ActivitySome people with brain symptoms have high neurotransmitter (NT) activity, and some have low. Common NT's include serotonin (5-HT), dopamine (DA), and norepinephrine (NE). I use the term “neurotransmitter activity” because it's not just about the amount of neurotransmitters present; it's also about the amount of receptors present that pick up NTs and remove them from the space between nerve cells.High Neurotransmitter ActivityToo much neurotransmitter activity can cause brain symptoms such as mania, psychosis, agitation, anxiety, panic, obsessions, compulsions, and hyperactivity. Reactions can occur if supplements or medications are given that further increase NT activity.Examples include:* Overmethylation* Slow COMT (involved in clearing DA and NE) and/or slow MAOA (involved in clearing 5HT, DA and NE)A variant on COMT and/or MAOA doesn't mean they are being expressed.What Increases Neurotransmitters?* SSRIs (Selective Serotonin Reuptake Inhibitor) increase serotonin activity* SNRIs (Serotonin and Norepinephrine Reuptake inhibitors) increase serotonin and norepinephrine activity.* Stimulant medications such as Ritalin and Adderall increase dopamine activity* SAMe and methionine increase serotonin and dopamine activityRemember that there can be times when there is a mixed picture, such as when someone is undermethylated and has a slow COMT.Low Neurotransmitter ActivityReactions can occur if supplements or medication decrease the neurotransmitter activity when it is already low. This could look like depression, apathy, fatigue, and brain fog.Examples include:* Undermethylation* Fast COMT (involved in clearing DA and NE) and/or fast MAOA (involved in clearing 5HT, DA and NE). The NTs are getting cleared too fast.What Decreases Neurotransmitters?* Folate, a nutrient that is good for a lot of people happens to be a big problem for many with psychiatric conditions. Most with underemethylation have low serotonin symptoms (depression and/or anxiety). While folate can help methylation, as an unfortunate aside, it can also further lower serotonin activity. Folate is in most multivitamins and B Complex vitamins. To learn more: Undermethylation, MTHFR & The Great Folate Debate.* Niacinamide can lowers DA and NE.Looking closely at someone's symptoms and traits and assessing methylation through bloodwork can help determine if NTs are too high, low, or mixed and what types of treatment to consider.3. Poor Detoxification or Toxic OverloadZincZinc is one of the most powerful tools I use in my work. Some people can easily tolerate it, while others can struggle. Here are some reasons someone may not tolerate zinc.* High copper—Zinc mobilizes copper. Moving too much copper at once can increase copper symptoms (anxiety, anger, hyperactivity, insomnia).* High toxicity—Zinc is a strong antioxidant. It is needed for the genetic expression of one of the most important antioxidants in our body, metallothionein.It took me 8 months to get my dose up to an optimal range, which is certainly not the norm. I unknowingly had significant mold toxicity at the time.When I start someone on zinc, I slowly build it up over 3-4 weeks. For some (like myself), even this is too fast.GlutathioneThis is the other major antioxidant. If someone is having difficulty tolerating it, they may have problems with detoxification and significant toxicity (metals, biotoxins like mold, and chemicals). These can start to be addressed in several other ways.BindersThese include bentonite clay, chlorella, activated charcoal, and cholestyramine. They bind toxins, especially mold toxins, in the GI tract. If they are started too quickly, the toxins they are supposed to remove get stirred up, which stirs up symptoms. When people say they can't tolerate certain binders, they usually weren't started low enough.There are others, but these are the most common in my experience.4. Underlying Microbial or Microbiome IssueB6B6 is very important for brain health. It is needed for making serotonin, dopamine, and GABA. We use it in all the Walsh nutrient protocols to varying degrees. In the last 10 years, we've seen a decrease in B6 tolerance. It's not clear why. I'm including it in this section because the reactivity is suspected to be related to the microbiome. Perhaps in recent years, we have had collective damage to our microbiomes from toxins and rising EMF exposure. We don't know.The good news is that P5P, the active form of B6, is usually well tolerated. In my practice, I rely heavily on P5P. I will occasionally use it in combination with B6 (if tolerated) for those with especially high pyrroles.Methionine and/or SAMeBoth are used, though usually not together, to help address undermethylation. I suspect candida or mold when someone is having difficulties tolerating either of these. These nutrients are usually better tolerated once candida and/or mold are addressed (or are starting to get addressed).5. Die-OffAnything that kills off microbes, such as candida or mold, can cause a “die off” of those microbes, release toxins, and worsen symptoms. Antifungal supplements, antifungal medication, and probiotics may cause this type of reactivity. Antifungal medications include nystatin, diflucan, itraconazole, and amphotericin B.Herbs and food-based supplements can have antimicrobial effects. Turmeric is one example. There are many others, so it's always worth checking. Worsening symptoms might point to an underlying fungal or other microbial overgrowth. It may also suggest that appropriate binders may be needed first.Addressing or preventing die-offs could mean supporting detoxification, starting binders if necessary, and, again, starting low and going slow.Antidepressants, interestingly, have been shown in labs to have antifungal effects. This does make me wonder if some people who can't tolerate them are having die-off.Root CausesKnowing someone's history of reactions can help point to underlying root causes.As you can see, there are typically ways to help someone tolerate and go on to benefit from a needed supplement or medication.As always, I welcome your thoughts and experience.Until next time,CourtneyP.S. To learn more about non-patient consultations, treatment, and monthly mentorship groups, please visit my website at:CourtneySnyderMD.comMedical Disclaimer:This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine
956 - Black Cumin Seed Oil's Remarkable Benefits (Backed by Science)

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Play Episode Listen Later Mar 3, 2025 36:32


Black cumin, also known as black seed oil, is an ancient remedy that has a multitude of surprising benefits! I was very impressed to find it improves fungal overgrowth, thyroid health, cholesterol and more. I'll dive into 10 health benefits of black cumin plus offer my recommended protocols.   Watch more videos like this

The Baby Manual
406 - Diapering and Pottying

The Baby Manual

Play Episode Listen Later Feb 5, 2025 29:49


Dr. Carole Keim talks about diapers and potty training your babies and toddlers in this episode. She discusses disposable versus cloth diapers, and the benefits of both in terms of convenience, expense, and sustainability. She shares practical advice on potty training by highlighting which items are most useful in assisting your baby in the transition from diapers to the potty. The best things to buy are highlighted here for new parents.Dr. Keim explains, in a quick summary, that the stuff that you'll need for diapering and pottying are probably some disposable diapers, some cloth diaper insides and outsides if you're using cloth, a diaper pail, some diaper creams, and then some potty training supplies. She details the best of each item, what to look for, and why it's helpful. She also explains different kinds of diaper rash and how to treat and prevent rashes. Any questions you have will be answered here or discussed in depth in previous seasons of The Baby Manual.In this episode:Disposable: Disposable diapersWater wipesDiaper pail - diaper genieDon't need: wipe warmer, peepee teepee  Cloth: Diaper outsidesDiaper insides (diaper service)Diaper pail - UbbiDon't need: Petroleum-based creams are the enemy of cloth diapers Diaper creams: Petroleum based (Vaseline, Aquaphor, A&D ointment)Zinc-oxide based (Desitin)Calendula creams - can be used instead of petroleum for cloth diapering Antifungal creams/ointments - clotrimazole, terbinafine, nystatin  Antibacterial ointments - bacitracin, neosporin, mupirocin Diaper cream spatulaPotty training: Potty chair for floor (for each room)Potty seat adapterStep stool Padded underwear (tinyundies) Info in my book The Baby ManualDon't need: sticker charts, a floor potty for the bathroom As an Amazon Associate, I earn from qualifying purchases.Dr. Keim has extensively researched the information presented in this episode. She is pulling on the knowledge of hundreds of thousands of new parents, other pediatricians, doctor moms, the Academy of Pediatrics, and breaking pediatrics news sites. Her insight and knowledge on alternative and holistic treatments can be found in her book Holistic Mamas Handbook, and her first book, The Baby Manual, covers year one of a baby's life. Follow Dr. Carole Keim on her TikTok and YouTube channels for additional tips and advice on babies and toddlers.   Resources discussed in this episode:The Holistic Mamas Handbook is available on AmazonThe Baby Manual is also available on Amazon--Dr. Carole Keim MD: linktree | tiktok | instagram

ASHPOfficial
Clinical Conversations SCSS: Antifungal TDM Controversies

ASHPOfficial

Play Episode Listen Later Dec 6, 2024 33:22


Antifungal therapeutic drug monitoring is a critical component of individualized, precision treatment for fungal infections and for antifungal stewardship. Antifungal therapeutic drug monitoring can help improve outcomes through minimizing toxicity associated with supratherapeutic drug levels and prevent treatment failure from subtherapeutic levels. Also, in vitro studies have shown that suboptimal drug levels can lead to antifungal resistance, supporting therapeutic drug monitoring's potential role in preventing the emergence of antifungal-resistant organisms. This episode podcast, we discuss outcome data when antifungal TDM is used, role of antifungal TDM with isavuconazole and echinocandins, TDM in outpatient settings, and other controversies. We will also highlight the recent antifungal TDM insights published by SIDP.   The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

Digest This
225: Stop Getting Sick With This Antimicrobial, Antiviral, & Antifungal From Nature | Carly Kremer

Digest This

Play Episode Listen Later Nov 20, 2024 70:45


In this episode, you'll discover all the benefits propolis can offer for your body and immune system. If you're looking for an alternative to antibiotics, antiviral medications, immune support, digestive support, sleep aids, and even help to combat and detox your system from microplastics, keep listening. In this interview, I sit down with Carly Kremer, the founder of Beekeeper's Naturals, a holistic supplement company that integrates and uses bee-derived products such as propolis, royal jelly, raw honey, and bee pollen synergistically to support the immune system, as well as address issues like PMS, menopause, sleep, energy, leaky gut, brain health, and even fertility. We also debunk the myth of glyphosate in honey, discuss whether organic honey really exists, explore whether the sugar in honey causes blood sugar spikes, and so much more. It's flu season, and if you're someone who always gets sick or struggles with an autoimmune system, this episode might provide the information you need for better health. I can't wait for you to listen! And remember to share this episode with anyone you think could benefit from it—we all can benefit from better health. Get 20% off + FREE bag of Beekeeper's Naturals throat lozenges  Use code: DIGEST beekeepersnaturals.com/DIGEST  Topics Discussed: - Curing tonsillitis - What propolis is - Propolis benefits - How to help with menopause symptoms - How to improve sleep - How to gain energy naturally - Nature's aid to autoimmune issues - Boosting fertility - Boosting the immune system - Royal jelly benefits - Leaky gut aids - What blocks microplastics from harming our brain - Is organic honey a scam? - Glyphosate in honey - The effects of honey on blood sugar As always, if you have any questions for the show please email us at digestthispod@gmail.com.  And if you like this show, please share it, rate it, review it and subscribe to it on your favorite podcast app.  Sponsored By:  Equip Foods Code DIGEST gets you 20% off at Equipfoods.com/digest LMNT  Get your FREE sample pack with any LMNT purchase at drinklmnt.com/DIGEST AquaTru Go to AquaTru.com enter code: DIGEST at checkout for 20% off Check Out Bethany: Bethany's Instagram: @lilsipper YouTube Bethany's Website My Digestive Support Protein Powder Gut Reset Book  Get my Newsletters (Friday Finds)

AAD's Dialogues in Dermatology
Bonus: Antifungal Resistant Dermatophytes

AAD's Dialogues in Dermatology

Play Episode Listen Later Sep 20, 2024


Avrom S. Caplan, MD, FAAD, Jeremy Gold MD/MS, Dallas Smith, MS, PharmD interviewed by Jackie Dosal, MD, FAAD

The Synthesis of Wellness
138. Pathogenicity of Candida Overgrowth | Understanding Candida-Produced Proteases, Phospholipases, & Candidalysins; Symptom Causation; & Key Strategies to Address Pathogenic Overgrowth

The Synthesis of Wellness

Play Episode Listen Later Aug 30, 2024 23:37


In today's episode, we explore the complex interactions between Candida and the gastrointestinal tract, examining how this fungus can transition from harmless commensal to pathogenic state that disrupts gut barrier functions. We dive into Candida's ability to undermine mucosal integrity through the production of candidalysin and other virulence factors like secreted aspartyl proteases, which specifically target and degrade tight junction proteins such as claudins and occludins. We'll explore the layered structure of the intestinal mucus barrier, its role in immunological defense, and how Candida's biofilm-forming capabilities further facilitate its pathogenicity. Lastly, we'll discuss tools and strategies for mitigating Candida overgrowth. Topics: 1. Gastrointestinal Tract Anatomy / Barrier Function - Mucus Layer - Description of the gastroprotective mucus barrier - Differences in mucus architecture between the small and large intestines - Composition: mucins, immunoglobulins (IgA), antimicrobial peptides - Intestinal Epithelium - Structure and function of the epithelial cell layer - Roles of different epithelial cells: enterocytes, goblet cells, enteroendocrine cells, Paneth cells - Lamina Propria - Immune cell types 2. Integrity of Tight Junctions - Tight junction proteins: claudins, occludins, junctional adhesion molecules (JAMs) - Mechanisms of tight junction regulation and response to changes in the gut environment - Impact of physiological and pathological factors on tight junction dynamics 3. Candida Pathogenicity Mechanisms - Adherence and Biofilm Formation - Mechanisms facilitating Candida adherence to epithelial cells - Structural and functional implications of biofilm formation - Enzymatic Disruption of Tight Junctions - Role of Candida-secreted aspartyl proteases (Sap) and phospholipases in degrading tight junction components - Immune System Interaction - Triggering of inflammatory cytokines by Candida presence and their effects on gut barrier function 4. Candidalysin: A Specific Virulence Factor - Genetic basis for candidalysin production via the ECE1 gene - Mechanism of action: disruption of epithelial cell membrane integrity, pore formation, and cellular damage 5. Clinical Manifestations of Candida Overgrowth - Gastrointestinal symptoms: bloating, gas, diarrhea, constipation, abdominal pain - Systemic effects: fatigue, brain fog, skin issues, mood disturbances - Nutrient absorption impairments leading to deficiencies 6. Strategies - Biofilm Disruption - Agents targeting biofilm integrity and adherence properties - Antifungal and Enzymatic Tools - Natural antifungals - Role of enzymatic supplements in biofilm and cell wall degradation - Immune Modulation and Gut Microbiota Support - Immune-modulating agents - Probiotics and prebiotics to restore and maintain healthy gut flora Thank you to our episode sponsors: 1. Check out ⁠⁠Daily Nouri⁠⁠ and use code ⁠⁠CHLOE20⁠⁠ for 20% off your order. 2. Check out ⁠⁠⁠⁠⁠⁠⁠Liver Medic ⁠and use code Chloe20 to save 20% on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠"Leaky Gut Repair"⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Brendan's YouTube Channel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/livermedic⁠⁠⁠⁠⁠⁠⁠⁠⁠ Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

We.Hannabis - Educate & Advocate Cannabis and CBD
Patchouli Essential Oil: Earthy Elixir for Mind and Body | The Strange Apothecary

We.Hannabis - Educate & Advocate Cannabis and CBD

Play Episode Listen Later Aug 23, 2024 5:46


Unveil the deep, musky world of Patchouli Essential Oil in our latest video feature from The Strange Apothecary. Known for its distinctive scent and versatile therapeutic benefits, patchouli has been cherished across various cultures for centuries. From traditional uses in ancient medicine to modern-day aromatherapy and skincare, discover how this potent oil can enhance your health and well-being. What You'll Discover in This Video: Historical Roots: Explore the ancient origins of patchouli in Asia, where it was used for medicinal purposes and as a luxury moth repellent in stored textiles. Learn about its rise to popularity in the West during the 1960s and its enduring presence in perfumery and holistic health practices. Chemical Composition: Understand the key components like Patchoulol and Alpha-Guaiene that grant patchouli oil its powerful antiseptic, anti-inflammatory, and aromatic properties. Health Benefits: Mood Enhancement: Dive into how patchouli oil's calming aroma helps alleviate stress and anxiety, promoting emotional well-being. Pain and Inflammation Relief: See how its anti-inflammatory effects can soothe conditions like arthritis and skin irritations. Antifungal and Antiseptic Uses: Learn about its efficacy in treating fungal infections and healing wounds. Beauty Benefits: Skincare: Discover the regenerative properties of patchouli oil for reducing scars, acne, and wrinkles, and how it balances oil production for both oily and dry skin types. Hair Care: Find out how it can prevent hair loss, combat dandruff, and enhance the hair's shine and overall health. Practical Applications: From its traditional role in ceremonies and medicinal treatments to contemporary uses in aromatherapy, skincare products, and even insect repellents. Usage Tips: Topical Application: Guidelines on how to mix patchouli oil with carrier oils for safe and effective skin and hair treatments. Aromatherapy: Tips for using patchouli oil in a diffuser to enhance your living space or relax the mind. Safety Precautions: Key safety advice for using patchouli oil, including conducting a patch test and guidelines for use during pregnancy and around pets and children. Whether you're drawn to its rich aroma or interested in its health-promoting properties, this video will provide you with comprehensive insights into making the most of Patchouli Essential Oil.

Infectious Disease Puscast
Infectious Disease Puscast #60

Infectious Disease Puscast

Play Episode Listen Later Aug 6, 2024 48:08


On episode #60 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/18/20 – 7/31/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Olympics Swimming in the Seine (NYTimes) Viral Twice-Yearlylenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women (NEJM) Consensus definitions of Cytomegalovirus Infection and Disease in Transplant Patients (CID) The recombinant shingles vaccine is associated with lower risk of dementia (Nature Medicine) Association of the incidence of postherpetic neuralgia with early treatment intervention of herpes zoster (International Journal of Infectious Diseases) Bacterial Updated guidelines for antimicrobial resistant gram-negative infections (IDSA) Put the Vanc Down, Flip it and Reverse it: Comparison of vancomycin and daptomycin (OFID) Durations of antibiotic treatment for acute otitis media and variability in prescribed durations (Journal of Pediatric Infectious Diseases Society) Fungal Adjunctive single-dose liposomal amphotericin to prevent cryptococcal meningitis in people with human immunodeficiency virus (HIV)–associated cryptococcal antigenemia and low plasma cryptococcal antigen (CrAg) titers(CID) Stagonospora cutaneous infection in a kidney transplant recipient: First human case (Transplant Infectious Disease) European Study of cerebral aspergillosis treated with Isavuconazole: an EFISG study (CID) Parasitic Rollout of world's second malaria vaccine begins in Ivory Coast (Healio) Executive summary: Evaluation and management of delusional infestation(CID) Parasitic contamination of soil in the Southern United States (ASTMH) Miscellaneous The potential benefits of delaying seasonal influenza vaccine selections for the northern hemisphere: A retrospective modeling study in the United States (JID) Music is by Ronald Jenkees

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine
903 - Eat These 7 Foods EVERY DAY for SIFO & Candida (Easy Fix!)

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Play Episode Listen Later May 23, 2024 26:37


Eating the right foods can seem impossible when you're healing candida overgrowth and SIFO! The good news is, there are still great food options that can also help you heal! In this episode, I'll give you a list of 7 foods to eat every day, what foods to personalize to your needs, and what to avoid in order to fix candida overgrowth and SIFO. Watch now!  

JAMA Network
JAMA Dermatology : Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae

JAMA Network

Play Episode Listen Later May 15, 2024 18:31


Interview with Sudha Chaturvedi, PhD, author of Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae. Hosted by Adewole S. Adamson, MD, MPP. Related Content: Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae

JAMA Dermatology Author Interviews: Covering research on the skin, its diseases, and their treatment
Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae

JAMA Dermatology Author Interviews: Covering research on the skin, its diseases, and their treatment

Play Episode Listen Later May 15, 2024 18:31


Interview with Sudha Chaturvedi, PhD, author of Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae. Hosted by Adewole S. Adamson, MD, MPP. Related Content: Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae

Naturally Savvy
EP #1353: Integrating Antifungal Foods and Spices to Clear Out Unhealthy Candida

Naturally Savvy

Play Episode Listen Later Apr 19, 2024 37:46


SummaryIn this conversation, Lisa Davis and Amber Romaniuk discuss the connection between emotional release and weight loss. Lisa shares her experience of feeling better and losing weight after releasing emotions through crying. Amber explains that emotional release helps to reduce inflammation and water retention in the body. They also discuss Lisa's food sensitivities and the importance of eating whole foods and avoiding processed ingredients. Overall, the conversation highlights the importance of addressing emotional well-being and making mindful food choices for optimal health. In this conversation, Amber Romaniuk and Lisa Davis discuss the impact of chemicals and pesticides on the body's sensitivity to certain foods. They explore the connection between gut health, candida overgrowth, and food sensitivities. Amber provides recommendations for soothing and strengthening the intestinal lining, including the use of collagen, marshmallow root, and L-glutamine. They also discuss the integration of antifungal foods and spices, as well as the importance of addressing emotional eating and hormone imbalances. The conversation concludes with a reminder to approach the protocol gently and to monitor symptoms throughout the process.Keywordsemotional release, weight loss, inflammation, water retention, food sensitivities, whole foods, processed ingredients, chemicals, pesticides, sensitivity, food, gut health, candida overgrowth, food sensitivities, intestinal lining, collagen, marshmallow root, L-glutamine, antifungal foods, spices, emotional eating, hormone imbalancesTakeawaysEmotional release can contribute to weight loss by reducing inflammation and water retention in the body.Addressing emotional well-being is just as important as physical healing for overall health.Food sensitivities can impact overall well-being and it's important to make mindful food choices.Eating whole foods and avoiding processed ingredients can help improve health and reduce symptoms. Chemicals and pesticides in food can contribute to the body's sensitivity to certain foods.Gut health and candida overgrowth can play a role in heightened food sensitivities.Soothing and strengthening the intestinal lining can help reduce food sensitivities.Integrating antifungal foods and spices can support the body's ability to clear out unhealthy candida.Addressing emotional eating and hormone imbalances is important for overall health and well-being.Sound Bites"Releasing emotions can help release weight.""Reducing inflammation can lead to weight loss.""Weight loss is never just physical, there's a huge emotional component.""Thank you body for speaking to me.""The sensitivity can be a superpower.""The gut flora plays a role in heightened sensitivities to foods."Chapters00:00Introduction and the Impact of Emotional Release on Weight Loss05:07The Connection Between Emotional Well-being and Physical Health09:19Navigating Food Sensitivities and Making Mindful Food Choices22:07Addressing Emotional Eating and Hormone ImbalancesAI show notes are experimental. Did you find them useful?

Infectious Disease Puscast
Infectious Disease Puscast #52

Infectious Disease Puscast

Play Episode Listen Later Apr 16, 2024 34:09


On episode #51 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/28 – 4/10/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Winter vomiting disease (Open Forum Inf Dis) Ceftriaxone-Resistant Gonorrhea — China, 2022 (MMWR) Give me five days of antibiotics (JPIDS) Where did this come from (JPIDS) Differentiating cellulitis from pseudocellulitis (JAMA Derm) FLIR One Pro Neonatal Elizabethkingia anophelis meningitis from the water reservoir of automated infant milk dispenser (Eurosurveill) d-Mannose for Prevention of Recurrent UTI Among Women (JAMA Int Med) Oral vaccine for UTI potential alternative to antibiotics (Eurek!Alert) Oral vaccine for UTI trials BJUI one and BJUI two and NEJM NLRP3 inflammasome activation and type I interferon signaling predispose to necrotizing fasciitis (Cell Rep Med) Candida deep sternal wound infections: a consequence of antibiotic use? (OFID) Candida auris in US Correctional Facilities (Emerg Inf Dis) Scedosporiosis and lomentosporiosis: difficult-to-treat rare mold infections (Clin Micr Rev) Meeting the consultation surge (OFID) Music is by Ronald Jenkees

Vitality Radio Podcast with Jared St. Clair
#413: Common Misconceptions About Colloidal Silver and the Power of Topical Silver Gel with Keith Moeller

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Mar 16, 2024 58:58


Colloidal Silver might be the most criticized natural product out there. The truth is, it's one of the most clinically studied! On this episode of Vitality Radio, Jared brings Keith Moeller back to the show to talk about the most common misconceptions about the safety of all types of silver and what type has the most clinical research backing its efficacy. You'll also learn about Vitality Nutrition's new Nano-Silver Skin Gel, its many uses, and the research behind it. Keith Moeller, ND is CEO and a founder of SilverCeuticals Inc. with almost 40 years of experience working in the silver industry. He has co-authored many papers, textbooks, and other publications on silver, a number of which have been peer-reviewed and published in leading wound care, science, and health journals.Products:Nano-Silver ProductsAdditional Information:Silver - Nature's Natural Healer (free digital book)#367: Your Silver User's Guide: Colloidal, Ionic, Nano…What Does It All Mean, Is It Safe, And Does It Work?Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

I AM BIO
“On My Own”—Desperate to Stop a Resistant Bacterial Infection (REDUX)

I AM BIO

Play Episode Listen Later Feb 6, 2024 27:42


Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it's normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to mad scientist, to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/

The Robert Scott Bell Show
The RSB Show 1-17-24 - Erika Escue, Trauma And Healing, ‘Pentagon' For Diseases, Echinacea

The Robert Scott Bell Show

Play Episode Listen Later Jan 18, 2024 136:06


TODAY ON THE ROBERT SCOTT BELL SHOW: The Collapse of Credentialism, Erika Escue, Trauma and healing, Getting over the victim mentality, ‘Pentagon' for diseases, Chinese lab madness, Antibiotic Resistance, Antifungal resistance, AAP on GMOs, COVID jab recovery, Homeopathic Hit – Echinacea and MORE! http://www.robertscottbell.com/natural-remedies/the-collapse-of-credentialism-erika-escue-trauma-and-healing-getting-over-the-victim-mentality-pentagon-for-diseases-chinese-lab-madness-antibiotic-resistance-antifungal-resis/

Vitality Radio Podcast with Jared St. Clair
#389: More Amazing Herbal Medicines with Nikita and Max: Mullein, Oil of Oregano, Cat's Claw, Devil's Claw and Skullcap

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Dec 23, 2023 59:59


Max Willis and Nikita Austen are back with Jared on this episode of Vitality Radio to talk about more medicinal uses of nature's amazing herbs! This time they tackle five herbs  with wide ranging benefits from lung health to antimicrobial uses, pain, and nervous system support. You'll learn the benefits of these herbs and which ones you might want to keep on hand in your medicine cabinet.Nikita Austen is the Director of Education and Innovation Specialist for Solaray and Max Willis is Chief Innovation Science Officer for Solaray. Both always bring us such great education on herbs and their many uses!Products:Solaray Mullein LeafSolaray Oil of OreganoCat's ClawSolaray SkullcapSolaray Devil's ClawAdditional Information:Episode #355: Herbs of Calm: Passion Flower, Valerian, Holy Basil, Lemon Balm and MoreEpisode #351: Exciting New Discoveries in the Herbal Kingdom For Stress, Mood, Hormone Balance, Varicose Veins, and Much MoreEpisode #321: Four Amazing Herbs You May Not Know About: Fenugreek, Tongkat Ali, Activated Broccoli, and Black Seed Oil with Nikita AustenEpisode #320: A Sharp, Focused Mind using Bacopa and Lion's Mane with Nikita Austen

Mile 62
Episode 77: Toenail Fungus Treatment For Runners And Other Athletes

Mile 62

Play Episode Listen Later Dec 12, 2023 2:25


Toenail Fungus Treatment For Runners Tips on treating toenail fungus (onchomycosis). This video is great for all types of endurance athletes such as triathletes, ultra runners, distance runners, marathoners, and cyclists. A fungal nail infection is a common condition that can leave you with brittle, discolored nails, which is usually on your toes. It is very common for trail runners. Toe nail fungus is a lot like athlete's foot. But instead of affecting the skin on the bottom of your feet or between your toes, it invades your nails. The FDA has approved the use of tolnaftate for the treatment and prevention of athlete's foot and ringworm for over 50 years. Tolnaftate is used in well over 70 products worldwide. Formula 3 is not a suspension compound like many other products. The product has received the American Podiatric Medical Association's Seal of Approval. For best results, It is recommended to apply fast-acting, quick-absorbing Formula 3® Antifungal after taking a shower when the skin has the greatest capacity for absorption. Common types of toe nail fungus: A yeast toenail infection is usually white, a mold infection is generally a dull brown, and a dermatophyte infection is generally yellow.

The Top Line
'The Top Line': Turning down the toxicity of nature's most powerful antifungal

The Top Line

Play Episode Listen Later Dec 8, 2023 27:47


The antifungal agent Amphotericin B is highly effective against a wide range of deadly fungi and resistance is rare, even after decades of use. But it comes with a virtual guarantee of kidney damage, earning it the nickname “Ampho-terrible.”    Now, a better alternative might be on the way. Fierce Biotech Research's Helen Floersh spoke with Martin Burke, M.D., Ph.D., a chemistry professor and researcher at the University of Illinois and the founder of antifungal startup Sfunga Therapeutics, to get the story behind the new drug's design, its path to the clinic and how it could influence the next generation of antimicrobials. To learn more about the topics in this episode:  Potent new drug has all the power of nature's strongest antibiotic, without the toxicity  See omnystudio.com/listener for privacy information.

Science Will Win
Part 1 – The Battle Against Antibiotic Resistance

Science Will Win

Play Episode Listen Later Nov 15, 2023 27:49


Medicine's struggle with antibiotic resistant bacteria is reaching a crisis point. In part one of this four-part series, host Jeremiah Owyang and expert guests delve into the world of antibiotics, exploring their history, the rise of antibiotic resistance, and the story of a patient whose life was forever changed by antibiotic-resistant bacteria. They break down the critical issues at stake and discuss the multifaceted solutions needed to combat this pressing crisis – including artificial intelligence.Featured Guests:Adrian Egli, Director, Institute of Medical Microbiology, University of ZurichJay Purdy, Vice President and Therapeutic Area Lead, Global Medical Affairs, Pfizer Antibacterial and Antifungal ProgramsMary Lynne Van Poelgeest-Pomfret, President, World Federation of Incontinence and Pelvic Problems Season 3 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It's produced by Wonder Media Network.

I AM BIO
“On My Own”—Desperate to Stop a Resistant Bacterial Infection

I AM BIO

Play Episode Listen Later Nov 14, 2023 27:42


Bradley Burnam woke up one morning, looked in the mirror and found one ear twice it's normal size and his face swollen and discolored. He would spend the next several years in and out of the hospital fighting a relentless infection that would not respond to available treatments. The experience took him from patient to "mad scientist" to biotech company founder. In this episode, Bradley takes us through his desperate journey to find a cure. We also talk with the leader of an organization helping to get more antimicrobials to the marketplace.Follow us on LinkedIn, X, Facebook and Instagram. Visit us at https://www.bio.org/Click HERE to watch the documentary-style film Race Against Resistance presented by the AMR Action Fund and funding support from Pfizer Shionogi and MSD.

Nature Podcast
How to tame a toxic yet life-saving antifungal

Nature Podcast

Play Episode Listen Later Nov 8, 2023 27:55


In this episode:00:46 Modifying a fungal drug to make it less toxicAmphotericin B is a drug used to treat life-threatening fungal infections. But while it is effective against many fungal species, it is also extremely toxic to kidneys, meaning it is mostly used as a drug of last-resort. This week, a team has unpicked the mechanism behind the drug's toxicity, allowing them to modify it and reduce side effects in human kidney cells. The researchers hope this new version of the drug could become a useful tool in fighting fungal diseases.Research article: Maji et al.09:00 Research HighlightsReconstructing woolly rhino DNA using samples from fossilized hyena dung, and a soft robot that can perform surgery inside a beating heart.Research Highlight: Woolly-rhino genome emerges from cave hyena's fossilized pooResearch Highlight: A robot performs heart surgery with a strong but delicate touch11:26 Phosphorus found at the edge of our GalaxyPhosphorus is a vital element for life and for planet formation, but although abundant in the inner part of the Milky Way, it has been undetected in the outer regions of our Galaxy. Now, researchers have identified phosphorus-containing molecules huge distances from Earth, although exactly how this phosphorus was created is unclear. The team suspect that lower-mass stars are behind the phosphorus generation, and believe that the detection of the element could broaden the range of planets that may be habitable in our Galaxy.Research article: Koelemay et al.18:14 Briefing ChatWhat Osiris-REx's hypersonic capsule return could teach researchers about asteroids hitting Earth's atmosphere, and the genetic studies that could help restore the genomes of Scotland's endangered ‘Highland tigers'.Nature News: Asteroid sampler's hypersonic return thrilled scientists: here's what they learntNature News: How to keep wildcats wild: ancient DNA offers fresh insightsSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

ACCP JOURNALS
Triazole Antifungal Therapeutic Drug Monitoring - Ep 124

ACCP JOURNALS

Play Episode Listen Later Oct 24, 2023 36:21


Which triazoles warrant therapeutic drug monitoring and when and how? This paper and podcast from the Society of Infectious Diseases Pharmacists describes the pharmacokinetic principles and pharmacodynamic targets of commonly used triazole antifungals. It provides the rationale for utility of TDM within each agent. Access the paper and supplements at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2850

Clinician's Roundtable
The Latest on Antifungal Vaccines: Updates from IDWeek 2023

Clinician's Roundtable

Play Episode Listen Later Oct 13, 2023


Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Stuart M. Levitz, MD Treating fungal infections can be difficult due to the limited treatment options available, but could antifungal vaccines help change that? To catch us up on the progress being made in immunotherapeutic and vaccine strategies, Dr. Charles Turck speaks with Dr. Stuart Levitz about the “Antifungal Vaccines: Where Are We At?” session he presented at IDWeek 2023.

Conference Coverage
The Latest on Antifungal Vaccines: Updates from IDWeek 2023

Conference Coverage

Play Episode Listen Later Oct 13, 2023


Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Stuart M. Levitz, MD Treating fungal infections can be difficult due to the limited treatment options available, but could antifungal vaccines help change that? To catch us up on the progress being made in immunotherapeutic and vaccine strategies, Dr. Charles Turck speaks with Dr. Stuart Levitz about the “Antifungal Vaccines: Where Are We At?” session he presented at IDWeek 2023.

Mayo Clinic Pharmacy Grand Rounds
A Rumble in the Fungal Jungle: Review of the New Antifungal Agents

Mayo Clinic Pharmacy Grand Rounds

Play Episode Listen Later Oct 11, 2023 33:32


Natalie T. Hagy, PharmD shares new antifungal agents in the pipeline, their novel mechanisms of action, and available formulations. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Microbe Magazine Podcast
Emerging Antifungal-Resistant Dermatophytes (JCM ed.)

Microbe Magazine Podcast

Play Episode Listen Later Sep 22, 2023 29:26


Fungi that are resistant to antifungal drugs have been very much in the news and even the subject of the hugely popular television program, The Last of Us. We talk with two experts in mycology and fungal susceptibility testing about the recent descriptions of terbinafine-resistant dermatophytes in the United States. Some of the questions we will address include:  • What are the manifestations of infections caused by terbinafine-resistant dermatophytes?  • What species, including novel species, of dermatophytes are more commonly resistant to terbinafine?  • How common is terbinafine resistance in dermatophytes in the U.S.? Guests: - Dr. Shawn Lockhart - Senior Advisor at the Centers for Disease Control - Dr. Nathan Wiederhold - Director of the Fungus Testing Laboratory and a Professor at UT Health San Antonio. This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. Editors in conversation is supported by the American Society for Microbiology, which publishes JCM. If you are a member of ASM, you can get up to 50% off the publication fees when you publish in JCM or any of the ASM journals. Visit https://journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Follow EIC, Alex McAdam on twitter for JCM updates via https://twitter.com/JClinMicro and co-host, Elli Theel at https://twitter.com/ETheelPhD. Subscribe to the podcast at https://asm.org/eic

The Nonlinear Library
EA - Why we should fear any bioengineered fungus and give fungi research attention by emmannaemeka

The Nonlinear Library

Play Episode Listen Later Aug 18, 2023 5:30


Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Why we should fear any bioengineered fungus and give fungi research attention, published by emmannaemeka on August 18, 2023 on The Effective Altruism Forum. Someone asked me a question after my talk on climate change and emerging fungal pathogens. The question was, why should we give attention to fungi when we know the risk of bioengineering it can be low. Hence the weight given to viruses and bacteria. I thought through and wondered that it is interesting and the EA community should understand why this should be considered. I think in my opinion we need to take fungi very seriously for so many reasons: What we know that makes fungi pathogen interesting: There are only three known anitifungal drugs against major fungi pathogens which are not very effective. The available antifungals have narrow spectrus and high toxicity, and because of the plasticity of the fungi genome resistance is developed very easily. The seriousness of this issue was brought to fore during the COVID-19 pandemic, a number of secondary infections due to fungi pathogens were reported . The emergence of Azole resistance Aspergillus in Europe and environment is a concern as the mortality due to antibiotics resistance and limited drugs can get up to 100%. There are no vaccines for fungi. Currently, there are no immunotherapy or any vaccine available for any fungal infection. More research and funding is needed. Here is a nice paper that shows how close we are to finding a vaccine against any fungi pathogen. Candida auris the first fungi to have emerged as a result of climate change is a fungal pathogen. This is really interesting because this yeast behaves like bacteria and is naturally resistant to some antifungals. It is difficult to treat and led to the shutting down of hospitals . A Detroit hospital will stop taking patients temporarily as it tries to contain an outbreak of a rare, but potentially deadly and drug-resistant fungus. Find link to this new here. It was first discovered in 2009 and have now been reported in all the continents of the world. The CDC gives reasons why this pathogen is a problem Why is Candida auris a problem? source It causes serious infections. C. auris can cause bloodstream infections and even death, particularly in hospital and nursing home patients with serious medical problems. More than 1 in 3 patients with invasive C. auris infection (for example, an infection that affects the blood, heart, or brain) die. It's often resistant to medicines. Antifungal medicines commonly used to treat Candida infections often don't work for Candida auris. Some C. auris infections have been resistant to all three types of antifungal medicines. It's becoming more common. Although C. auris was just discovered in 2009, it has spread quickly and caused infections in more than a dozen countries. It's difficult to identify. C. auris can be misidentified as other types of fungi unless specialized laboratory technology is used. This misidentification might lead to a patient getting the wrong treatment. It can spread in hospitals and nursing homes. C. auris has caused outbreaks in healthcare facilities and can spread through contact with affected patients and contaminated surfaces or equipment. Good hand hygiene and cleaning in healthcare facilities is important because C. auris can live on surfaces for several weeks 4. Fungi are the only species that have caused the complete extinction of a species. A newspaper reported thus "A deadly fungus that has driven more species to extinction than any other pathogen has spread across Africa unnoticed. Chytrid fungus, Batrachochytrium dendrobatidis, or Bd for short, is a highly infectious fungus that affects frogs, toads, salamanders and other amphibians(Source). Although various diseases, such as white-nose syndrome resulting from the European fungu...

Evidence Based Hair
Season 4, Episode 8 (Isotretinoin for SD, Iron Therapy, Memantine for TTM, Antifungal Resistance

Evidence Based Hair

Play Episode Listen Later Apr 9, 2023 68:51


Season 4, Episode 8

Pharm5
Patents ending soon, new antifungal approval, Senate on drug shortages, and more!

Pharm5

Play Episode Listen Later Mar 24, 2023 4:37


This week on Pharm5 Humira biosimilars Vyvanse, Symbicort, and more losing patents this year Rezafungin approval Senate Committee meets on drug shortages COVID-19 declassified   Connect with us! Listen to our podcast: Pharm5 Follow us on Twitter: @LizHearnPharmD   References: Sandoz receives US FDA approval for biosimilar Hyrimoz® (Adalimumab-adaz) high-concentration formulation. Novartis. http://bit.ly/3lBJ1rK. Published March 21, 2023. Accessed March 23, 2023. Humira [package insert].North Chicago, IL: AbbVie Inc. Accessed March 23, 2023. Stonehill M. Humira exclusivity expires in 2023: Will biosimilar boom benefit patients or industry? Healio. http://bit.ly/3lzQrvs. Published January 17, 2023. Accessed March 23, 2023. Amjevita™ (Adalimumab-Atto), first biosimilar to Humira®, now available in the United States. Amgen. http://bit.ly/3Z9gesm. Accessed March 23, 2023. Kansteiner F, Sagonowsky E, Becker Z, Dunleavy K, Liu A. The top 10 drugs losing us exclusivity in 2023. Fierce Pharma. https://bit.ly/3LGsm0N. Published March 13, 2023. Accessed March 23, 2023. FDA drug shortages. FDA Drug Shortages. http://bit.ly/3LLEAoY. Accessed March 23, 2023. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2022. www.ginasthma.org. Accessed March 23, 2023. Cidara Therapeutics, Inc. Cidara Therapeutics and Melinta Therapeutics announce FDA approval of Rezzayo™ (rezafungin for injection) for the treatment of Candidemia and invasive candidiasis. GlobeNewswire News Room. http://bit.ly/40utHMl. Published March 22, 2023. Accessed March 23, 2023. Thompson GR, Soriano A, Cornely OA, et al. Rezafungin versus Caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): A multicentre, double-blind, double-dummy, randomised phase 3 trial. The Lancet. 2023;401(10370):49-59. doi:10.1016/s0140-6736(22)02324-8 FDA Approves Rezzayo, a Novel Echinocandin. Infectious Disease Special Edition. https://bit.ly/3TAbn2d. Published March 23, 2023. Accessed March 23, 2023. Gauthier T. Rezafungin (Rezzayo). IDStewardship. http://bit.ly/3LHBn9X. Accessed March 23, 2023. O'Mary L. Cases of potentially deadly fungus jump 200%: CDC. Medscape. http://bit.ly/40lSRwC. Published March 22, 2023. Accessed March 23, 2023. Drug shortage health and national security risks: Underlying causes and needed reforms. Committee on Homeland Security & Governmental Affairs. https://bit.ly/3ZdX846. Published March 22, 2023. Accessed March 23, 2023. Biden signs Bill on COVID origins declassification. AP NEWS. http://bit.ly/3JCsOKJ. Published March 20, 2023. Accessed March 23, 2023. Pradhan R. End of Covid emergency will usher in changes across the US Health System. Kaiser Health News. http://bit.ly/40xC0H0. Published March 22, 2023. Accessed March 23, 2023.

Infectious Disease Puscast
Infectious Disease Puscast #21

Infectious Disease Puscast

Play Episode Listen Later Feb 6, 2023 38:07


On episode #21 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 1/18/23 – 2/1/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode The impact of cold temperature in the pattern of influenza virus infection (OFID) Janssen to discontinue Phase 3 Mosaico HIV vaccine clinical trial (JNJ) Randomized trial of vaccines for Zaire Ebola virus disease (NEJM) PD-1 blockade and lenalidomide combination therapy for Epstein-Barr virus infection (CMI) Outcomes of Daptomycin plus Ceftaroline vs alternative therapy for persistent MRSA bacteremia (IJAA) Detection of a novel strain of multidrug-non-susceptible Neisseria gonorrhoeae (The Lancet) Impact of a device to reduce blood culture contamination and false-positive central-line bloodstream infections (ICHE) Addition of anaerobic coverage for treatment of biliary tract infections (JAC) High dose Cefepime vs Carbapenems for bacteremia caused by Enterobacterales(OFID) Assessing the diagnostic performance of IGRAs for Mycobacterium tuberculosis (CID) Infective endocarditis after transcatheter aortic valve replacement (JACC) Discordant clinical and microbiological outcomes are associated with late clinical relapse in clinical trials for complicated UTIs (CID) Real-world use of bezlotoxumab and fecal microbiota transplantation for the treatment of Cdiff (OFID) Blastomycosis in New England (OFID) Management of invasive candidiasis in hematopoietic cell transplant recipients (TCT) Short course of Antifungal therapy in patients with uncomplicated Candida Bloodstream infection (OFID) Parasites and childhood stunting (Cell) Comparing complication rates of midline catheter vs. PICC line (OFID) Novel prion strain as the cause of chronic wasting disease in a moose (EID) Agreement of respiratory viruses' detection between nasopharyngeal swab and bronchoalveolar lavage in adults with pneumonia (CMI) Music is by Ronald Jenkees

#TheUndrGround
(Spotify Video) #Clips - Music Video Pull Ups

#TheUndrGround

Play Episode Listen Later Dec 13, 2022 40:15


N checks out some of his favorite music from artists like Midrange Meats, East Side Nesto, and Antifungal and talks the Balanciaga Scandal and more! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/undrground/message Support this podcast: https://anchor.fm/undrground/support

Ask Theory
093: [Medical Microbiology] Paano Nababawasan Ng Bisa Ang Mga Gamot Na Antifungal? (with Joshua Veluz)

Ask Theory

Play Episode Listen Later Sep 25, 2022 34:52


Joshua Veluz is a microbiologist and a licensed professional teacher. He is keen on discovering more applications of microorganisms that have the potential to propel the progress of human health, the environment, and society. We talked about studying the antifungal activity of Lactobacillus metabolites, medically relevant fungi and antifungal resistance, the roles marine microorganisms play in medical research, ESKAPE pathogens, working as a licensed professional teacher, and more. How to contact Joshua: Email: veluz.jt@gmail.com

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
736: Empiric vs Diagnostic Approach to Antifungal Therapy for High-Risk Neutropenic Patients with Persistent Fever

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Aug 4, 2022 3:16


Show notes at pharmacyjoe.com/episode736. In this episode, I'll discuss empiric vs pre-emptive antifungal therapy. The post 736: Empiric vs Diagnostic Approach to Antifungal Therapy for High-Risk Neutropenic Patients with Persistent Fever appeared first on Pharmacy Joe.

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
736: Empiric vs Diagnostic Approach to Antifungal Therapy for High-Risk Neutropenic Patients with Persistent Fever

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Aug 4, 2022 3:16


Show notes at pharmacyjoe.com/episode736. In this episode, I ll discuss empiric vs pre-emptive antifungal therapy. The post 736: Empiric vs Diagnostic Approach to Antifungal Therapy for High-Risk Neutropenic Patients with Persistent Fever appeared first on Pharmacy Joe.

Emerging Infectious Diseases
Detection of Antifungal-Resistant Trichophyton Strain in France

Emerging Infectious Diseases

Play Episode Listen Later May 4, 2022 19:57


Dr. Karen Wu, an EIS officer at CDC in Atlanta, and Sarah Gregory discuss the detection of an antifungal-resistant Trichophyton strain in France.

Eric Bakker - The Naturopath
What Is The Best Antifungal Supplement For Candida | Ask Eric Bakker

Eric Bakker - The Naturopath

Play Episode Listen Later Apr 26, 2022 3:40


All of your most burning questions on candida and diet answered by New Zealand Naturopath of 30 + years! In each bite-size episode, you'll get practical tips you can follow right away to improve your health and lifestyle. So go ahead and binge listen. --- Download My Candida Diet & Cleanse Guide Free Mobile App: IOS: https://apps.apple.com/ca/app/candida-diet-cleanse-guide/id1553653763 Android: https://play.google.com/store/apps/details?id=com.candida.crusher *New* Candida Diet Cleanse and Detox Planner Planner: https://amzn.to/3C9lH7u --- Subscribe to Eric Bakker - The Naturopath All of your most burning questions on candida and diet answered by New Zealand Naturopath of 30 + years! In each bite-size episode, you'll get practical tips you can follow right away to improve your health and lifestyle. So go ahead and binge listen. --- FOLLOW Eric Bakker - The Naturopath: YouTube: https://www.youtube.com/user/CandidaCrusher Twitter: https://twitter.com/ericbakker Facebook: https://www.facebook.com/ericbakker.ND?ref=tn_tnmn

The Nonlinear Library
EA - Antifungal Resistance - The Neglected Cousin of Antibiotic Resistance by Madhav Malhotra

The Nonlinear Library

Play Episode Listen Later Feb 5, 2022 1:26


Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Antifungal Resistance - The Neglected Cousin of Antibiotic Resistance, published by Madhav Malhotra on February 4, 2022 on The Effective Altruism Forum. For any researchers interested in healthcare and neglected problems, I recorded this podcast with an expert on antifungal resistance. Here are a few key stats (sources linked): Fungal diseases kill 1.7M people every year. Comparatively, cancer kills 10M per year - but also has a lot more funding & >10x more developed drugs. Fungal diseases are harder to treat than bacterial infections since fungal cells are like our cells. So drugs against them also have side effects on us. Large-scale research on them started 80 years after research on bacterial/viral diseases. More fungal species are infecting humans due to climate change. Since most fungi couldn't survive at high temperatures like in our body before. We have about 4x fewer antifungals than antibiotics being developed in any given year. But both fungi and bacteria are becoming resistant. If you have skills in biomedical or public health research and want to get involved in a more neglected field, feel free to reach out to the expert I interviewed. Or find more resources at the Global Action Fund for Fungal Infections Thanks for listening. To help us out with The Nonlinear Library or to learn more, please visit nonlinear.org.

Salad With a Side of Fries
Nutrition Nugget: Cinnamon

Salad With a Side of Fries

Play Episode Listen Later Jan 14, 2022 13:04


Nutrition Nugget! Bite-size, bonus episodes offering tips, tricks and approachable science. This week, Jenn's talking about Cinnamon. Can it really help us lose weight? Why is cinnamon used for gum and toothpaste flavors? What about Cancer? Are those claims true? How much is enough? In just a few minutes, Jenn answers all these questions and more! Like what you're hearing? Be sure to check out the full length episodes; new releases every Wednesday.  Have an idea for a nutrition nugget?   Submit it here:  https://asaladwithasideoffries.com/index.php/contact/         Become A Member: https://glow.fm/saladwithasideoffries/Want a Free Menu Plan from Jenn? https://www.tlsslim.com/bettermylifenow/weight-loss-profile/?

Salad With a Side of Fries
Nutrition Nugget: Peppermint

Salad With a Side of Fries

Play Episode Listen Later Dec 24, 2021 17:28


Nutrition Nugget! Bite-size, bonus episodes offering tips, tricks and approachable science. This week, Jenn's talking about peppermint. It's not just for Christmas! Is it really true that peppermint can help with everything from migraines and energy to weight loss and sleep? Does peppermint tea count? And why is that mint is such a popular flavor for toothpaste, mouthwash, gum...and candy canes? In just a few minutes, Jenn answers all these questions and more! Like what you're hearing? Be sure to check out the full length episodes; new releases every Wednesday.  Have an idea for a nutrition nugget?   Submit it here:  https://asaladwithasideoffries.com/index.php/contact/         Become A Member: https://glow.fm/saladwithasideoffries/Want a Free Menu Plan from Jenn? https://www.tlsslim.com/bettermylifenow/weight-loss-profile/?

#TheUndrGround
The Undrground Podcast - The Council

#TheUndrGround

Play Episode Listen Later Dec 20, 2021 114:42


Tune in as N talks Drakeo The Ruler's Passing, The Maxwell Case, Ross Walking off 85 South and more! With music from Antifungal, Soul, Arma other indie artists you'll only hear here on The Undrground! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/undrground/message Support this podcast: https://anchor.fm/undrground/support

Earth Wise
Wastewater And Ammonia | Earth Wise

Earth Wise

Play Episode Listen Later Oct 22, 2021 2:00


Ammonia is the second most produced chemical in the world.  More than half of it is used in agriculture to produce various kinds of fertilizer, to produce cotton defoliants that make cotton easier to pick, and to make antifungal agents for fruits.  Globally, ammonia represents more than a $50 billion a year market. Current methods […]

Dr. Howard Smith Oncall
Topical Antifungal Over-The-Counter Products Are Recalled

Dr. Howard Smith Oncall

Play Episode Listen Later Oct 7, 2021 1:11


  Vidcast:  https://youtu.be/0JzB-LNFuZQ   The FDA and Bayer US LLC are recalling Lotrimin® AF and Tinactin® over-the-counter (OTC) antifungal spray products.  These include products labeled as liquid and powder sprays for athlete's foot and jock itch. Involved are products with lot numbers that begin with TN, CV, or NAA.  Each of these is contaminated with unsafe levels of the organic solvent benzene.  Benzene is classified as a human carcinogen, and exposure to it can increase your risk of leukemia, bone marrow cancers, and other blood disorders all of which may be life-threatening.  If you or family members have these products, discontinue using them and discard them.  Contact Bayer by phone at 1-866-360-3266 for additional information.  To request a refund, take a photo of the product and visit lotrimin.com or tinactin.com.   https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/bayer-issues-voluntary-recall-specific-lotriminr-and-tinactinr-spray-products-due-presence-benzene   #tinactin #lotrimin #antifungal #benzene #cancer #recall  

VETgirl Veterinary Continuing Education Podcasts
Antifungal therapy with Dr. Andrew Hanzlicek | VETgirl Veterinary Continuing Education Podcasts

VETgirl Veterinary Continuing Education Podcasts

Play Episode Listen Later Sep 20, 2021 25:51


In today's VETgirl online veterinary CE podcast, we interview Dr. Andrew Hanzlicek, DACVIM, Veterinary Medical Director at Miravista Veterinary Diagnostics on everything you need to know about systemic mycoses infections in veterinary medicine. If you're not well versed in the clinical signs, treatment, and diagnostic work-up for blastomycosis, histoplasmosis, coccidioidomycosis, aspergillosis and cryptococcosis, tune in to learn it! Plus, we'll discuss what types of antifungals to reach for and how to monitor their effect! Today's VETgirl podcast is brought to you by MiraVista Veterinary Diagnostics, where we offer a wide array of diagnostic tests for systemic mycoses such as blastomycosis, histoplasmosis, coccidioidomycosis, aspergillosis and cryptococcosis as well as therapeutic drug monitoring for itraconazole. Our educational resource library provides guidelines to inform diagnostic and treatment decision making as well as current publications for reference. For more information and to receive educational newsletters, visit miravistavets.com.

Richard Syrett's Strange Planet
624 Colloidal Silver

Richard Syrett's Strange Planet

Play Episode Listen Later Sep 13, 2021 29:08


EPISODE #624 COLLOIDAL SILVER Richard talks with an inventor about making your own colloidal silver.   Guest: Bruce McBurney (deceased) was a self taught inventor, electrical and motor mechanic repairman, handy handyman according to the theory All known bacteria and viruses are killed by Colloidal Silver. In fact some 650 known bacterias are killed by Colloidal Silver. (You may want to research that yourself) But all these ugly little things in your body all have positive charges, as everything in your body works on a small amount of electric current. When you drink Colloidal Silver (which is a negative charge) it is attracted to these positive charges in your body the bad guys. If the particles size is smaller than .05 microns your colloidal generator makes the particle size 100 to 1000 times smaller than .05 microns, that allows this Colloidal Silver to go straight to the positive charge wherever it may be inside of you.   SUPPORT OUR SPONSORS!!!   Mystic Labs, Delta-8 Never Tasted This Good! The Premium manufacturer of the highest-quality and most trusted Delta-8 THC products available.  Use the Code CON15 and receive 15% off your order.  www.mysticlabsd8.com   C60EVO -The Secret is out about this powerful anti-oxidant. The Purest C60 available is ESS60.  Buy Direct from the Source.  Buy Now and Save 10% – Use Coupon Code: EVRS at Checkout!   Strange Planet Shop - If you're a fan of the radio show and the podcast, why not show it off?  Greats T-shirts, sweatshirts, mugs, and more.  It's a Strange Planet - Dress For It! BECOME A PREMIUM SUBSCRIBER FOR LESS THAN $2 PER MONTH If you're a fan of this podcast, I hope you'll consider becoming a Premium Subscriber.  For just $1.99 per month, subscribers to my Conspiracy Unlimited Plus gain access to two exclusive, commercial-free episodes per month. They also gain access to my back catalog of episodes. The most recent 30 episodes of Conspiracy Unlimited will remain available for free.  Stream all episodes and Premium content on your mobile device by getting the FREE Conspiracy Unlimited APP for both IOS and Android devices... Available at the App Store and Google Play. To become a subscriber CLICK HERE or go to www.conspiracyunlimitedpodcast.com and click on Get Access to Premium Episodes

The Dermatology Podcast
E32: Editor's Picks July 2021

The Dermatology Podcast

Play Episode Listen Later Jul 27, 2021 10:16


Join us as we go through the JEADV Editor's Picks of July 2021: (1) Novel presentation of pigtail hairs (2) Seeing the light: moving past sun protection factor and ultraviolet B when choosing sunscreen (3) Antifungal resistance may be spreading in Europe (4) Agreeing on the correct histopathologic diagnosis of melanoma Read the Editor's picks here: https://www.onlinelibrary.wiley.com/doi/10.1111/jdv.17389

Eric Bakker - The Naturopath
What Are The Best Antifungal Foods to Eat? | Eric Bakker

Eric Bakker - The Naturopath

Play Episode Listen Later Jul 19, 2021 5:54


All of your most burning questions on candida and diet answered by New Zealand Naturopath of 30 + years! In each bite-size episode, you'll get practical tips you can follow right away to improve your health and lifestyle. So go ahead and binge listen. --- Full video of this episode: https://www.youtube.com/watch?v=pHNUGHakii8 --- Download My New Candida Diet & Cleanse Guide Free Mobile App: IOS: https://apps.apple.com/ca/app/candida-diet-cleanse-guide/id1553653763 Android: https://play.google.com/store/apps/details?id=com.candida.crusher --- Subscribe to Eric Bakker - The Naturopath All of your most burning questions on candida and diet answered by New Zealand Naturopath of 30 + years! In each bite-size episode, you'll get practical tips you can follow right away to improve your health and lifestyle. So go ahead and binge listen. FOLLOW Eric Bakker - The Naturopath: YouTube: https://www.youtube.com/user/CandidaCrusher Twitter: https://twitter.com/ericbakker Facebook: https://www.facebook.com/ericbakker.ND?ref=tn_tnmn

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine
Antimicrobial Agents: When and How They May Help Your Health

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Play Episode Listen Later Jul 12, 2021 25:46


Antimicrobial agents include broad spectrum plant-based ingredients that are an option in tackling gut-related health problems. https://drruscio.com/antimicrobial-agents  My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/  If you're in need of clinical support, please visit https://austinfm.com/  Looking for more? Check out https://drruscio.com/resources 

This Week in Microbiology
245: Bacteria that protect bees from fungi

This Week in Microbiology

Play Episode Listen Later Jul 3, 2021 50:14


In this episode, how polysaccharides keep cyanobacteria afloat in the oceans so that they can carry out photosynthesis, and a symbiotic bacterium that protects honey bees from fungal infections. Become a Patron of TWiM! Links for this episode: Bacterial blooms and polysaccharides (eLife) Social life of cyanobacteria (eLife) Bacteria that protect bees from fungi (mBio) First 21 days of a bee's life (YouTube) antiSMASH (Nucl Acids Res) Delaney Miller's website Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine
Answers on Antifungal Medication, Curcumin, and Hydrogen Sulfide SIBO

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Play Episode Listen Later May 26, 2021 44:57


On today’s podcast, we will cover listener questions, including… Will an oral antifungal medication destroy my gut? Do you recommend bismuth thiol biofilm disruptors for hydrogen sulfide SIBO? Does curcumin really help with inflammation in rheumatoid arthritis? Is there enough research to support this? What should I do if I suffer from burning pain in my stomach, and HCl, apple cider vinegar, and digestive enzymes don't help? How do I get off of the PPI I'm taking when I have reflux and EOE? My eczema of 10 years cleared up while I was on the modified fast and diet from Healthy Gut, Healthy You, but it’s starting to come back as I add foods back in. What should I do? Do you recommend the peptide BPC-157 for gut issues? https://drruscio.com/answers-on-oral-antifungal-medication-bismuth-thiols-curcumin-stomach-acid  My book Healthy Gut, Healthy You is available at https://drruscio.com/getgutbook/  If you're in need of clinical support, please visit https://austinfm.com/  Looking for more? Check out https://drruscio.com/resources 

One Hour Show
Brand New Antifungal

One Hour Show

Play Episode Listen Later Apr 8, 2021 246:18


It's new to me, anyway.

Doc Handal Speaks! Listen Up, A Doctor's Insider Tips

Studies indicate tea tree oil has amazing antiviral properties. Everyone has the SARsCoV-2 on their minds so I must let you in on this wonderful adjunct to my medical care. Have a listen to my latest podcast on this beneficial oil. In the podcast, I refer to this blog for those that wish to read more. Cats and dogs can't be exposed to tea tree oil.

Empowering You Organically - Video Edition
This Anti-Aging Serum Breaks All the Rules

Empowering You Organically - Video Edition

Play Episode Listen Later Feb 9, 2021 43:31


When Should You Start Using Anti-Aging Skin Care Products? The wealth of products available these days to target visible signs of aging such as fine lines, crow’s feet, dark under-eye circles and dull skin are a gift and a curse. The options are so extensive that it can actually feel quite overwhelming figuring out a skin care regimen that works best. So when and where does one begin?   Experts agree that skin starts to age around 20 years old and recommend that you start the road to prevention early. “I recommend my patients to start incorporating anti-aging skin care products in their 20s and 30s, when our skin slowly starts to lose collagen,” says Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City.   Face Serum Benefits for All Ages Just like it’s never too soon to start being physically active or eating mindfully, this fundamental aspect of life also applies to skin care. Using serums loaded with incredibly important ingredients before you start seeing signs of aging and environmental assault means you'll be on track for getting (and keeping) the beautiful skin you want now and in the long term.   Keep in mind that just like your body never "gets used" to eating nutrient-dense foods, nor does your skin get used to great ingredients. Your skin craves and needs generous amounts of beneficial ingredients like antioxidants, skin-replenishing, and skin-restoring ingredients because each group helps skin be healthy and stay young-looking. Using them now does not mean they won’t work "when you really need them"; rather, they will be working for you every day of your life.   Of course, these ingredients also work after signs of aging appear, but without question, sooner is better than later!     Roots of The Aging Concept Referring to Greek mythology, the quest for immortality is embodied in the story of Eos, the immortal goddess of dawn. She falls madly in love with Tithon, a mortal human. Not supporting the idea of seeing him die, she claims for him eternity. Zeus agrees, but poor Eos realizes her mistake too late, as what she wanted for Tithon was not eternity but eternal youth. She will therefore be condemned to see him eternally grow old. This myth of ancient Greece refers directly to the current perception of aging: accept the temporary nature of life, while differing as long as possible the appearance of the signs of aging.   Today, in industrialized countries, this quest seems strongly motivated by the fear of social exclusion. Indeed, a study conducted on a cohort of 1,713 American women, over 50 years old and mostly of Caucasian type, highlights a great psychological suffering based both on the image that these women have of themselves but also on the degrading image that the rest of society sends back to them.   More than 50% of these women reported the perception of physical changes that occur during aging, notably sagging skin and wrinkles. Their cognitive adaptations to the physical experience of aging and the psychological experience of body image altered in parallel. This point is extremely important because it shows how much women correlate the initiation of their aging-related psychological malaise with the appearance of visible signs revealing their age.    Let’s get scientific for a minute…   With age, our tissues lose their function and capacity to regenerate after being damaged. A study published today in Cell by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Centro Nacional de Análisis Genómico of the Center for Genomic Regulation (CNAG-CRG) explains how dermal fibroblasts age.   The main conclusion drawn is that these fibroblasts lose their cell identity, as if they had "forgotten" what they are, and consequently their activity is altered, thus affecting tissue. The study reveals the cellular and molecular pathways affected by aging and proposes that they could be manipulated to delay or even reverse the skin aging process.   The skin is the most exposed organ of the body, and it functions as a barrier against external aggressions. It frequently experiences the direct effects of environmental exposure, including UV radiation and air pollution. Alterations in skin structure and physiology occur as natural consequences of aging and contribute to diminished skin health. These damages can be aggravated by external factors and, combined with lifestyle, result in significant biological alterations, characteristic of premature aging.   A fibroblast is a type of cell that is responsible for making the extracellular matrix and collagen.   Fibroblasts are large, flat, elongated (spindle-shaped) cells possessing processes extending out from the ends of the cell body. ... Fibroblasts produce tropocollagen, which is the forerunner of collagen, and ground substance, an amorphous gel-like matrix that fills the spaces between cells and fibres in connective tissue.   Together, this extracellular matrix and collagen form the structural framework of tissues in animals and plays an important role in tissue repair. Fibroblasts are the main connective tissue cells present in the body.   Dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame.     Why the Science Lesson? Organixx Skin has released REVERSE our anti-aging serum! When we were experimenting with formulations and ingredients, we did our science homework. We wanted to provide you with a clean, healthy, and effective product that helps turn back the hands of time.   The synergy of the fresh, clean, and pure ingredients in REVERSE address the root cause of skin aging in the 21st century – the inside factors like diminished collagen production and aging dermal cells - as well as the outside factors like UV damage and environmental factors.   Let’s dive into each ingredient…   Croda Juvinity™  Visibly reduces the signs of aging on the face and décolleté. Smoothes wrinkles, restructures and densifies the dermis. Juvinity™ delays cell senescence. It limits oxidative stress and telomere shortening to ensure optimal metabolism and replication rate as a young cell. Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Reactivates the synthesis of major dermal constituents, preserves the cytoskeleton functionality and prolongs cell lifespan by maintaining telomere length.     ARGAN STEM CELLS Referred to as “liquid gold”, argan oil is fast-absorbing and known for increasing cell regeneration, reducing the appearance of fine lines and wrinkles. Argan oil is also rich in phenols and carotenes, antioxidants that protect the skin from aging free-radical damage.   Argan stem cells are well known for their anti-aging properties. They are regenerative and work to strengthen skin's elasticity.  Argan stem cells also penetrate the skin at a deeper level, so are able to help fight the signs of aging.   Argan stem cells are the only proven stem cells with the ability to penetrate the skin's dermis, meaning they can help protect and revitalize human dermal stem cells!     RASPBERRY SEED OIL Raspberry seed oil is rich in EFAs (essential fatty acids), primarily linoleic and linolenic acids. It contains very high levels of tocopherols (Vitamin E), which act as antioxidants, and carotenoids (Vitamin A).       Because of its composition, raspberry seed oil possesses superior anti-inflammatory qualities which makes it a nice addition to face, lip and sunscreen products.    Absorbs UV rays (Oomah et al., 2000) although its efficacy as a sunscreen has not yet been confirmed. Anti-inflammatory due to high content of alpha linolenic acid (the highest in any fruit seed oil) and phytosterols, therefore helpful for eczema and psoriasis. Very high in Vitamin E – an antioxidant. Antioxidants in skin care are important to prevent oxidative damage, which can lead to premature skin aging and skin cancer. Very high levels of phytosterols that can help reduce trans-epidermal water loss, thereby helping to keep skin moisturized. Phytosterols also help to repair skin damaged by environmental factors including sun damage. It’s a great source of alpha linolenic acid – an essential fatty acid that has regenerative and anti-aging skin benefits. Red raspberry seed oil also has a low comedogenic rating of 0-1, meaning it’s not likely to clog pores.   CRANBERRY SEED OIL Cranberry Seed Oil, cold pressed from the seed of the super fruit, is unique among the fixed oils because it contains a very high essential fatty acid profile, along with a good mixed tocopherols and tocotrienols (vitamin E) content, high phytosterols, and a 1:1 ratio of omega 3 to omega 6 essential fatty acids which gives it excellent anti-oxidant activity and skin nurturing benefits.   Cranberry Seed Oil contains one of the highest antioxidants and phytosterols content of any of the vegetable / fruit oils, making it an excellent addition to your natural sun protection products where it will help to prevent photo damage.   Anti-oxidants that are consumed can reach the skin but, with free radical damage being the heaviest assault on the skin, and the cause of almost all of the signs of aging and unhealthy skin, it is beneficial to apply them topically where their protection can go to work immediately.   Antioxidant Protection Skin Conditioning and Restructuring Vitamins A, C, E, and K Enhanced Cellular Function Aids in the Skin's Absorption, and Utilization, of Essential Fatty Acids Cranberry seed oil has the perfect ratio of omega-3 to omega-6 fatty acids, meaning it will absorb into your skin very well. Exceptional Skin Moisturizer Skin Tightening Activity Natural brightener. If your face is looking a little on the dull side, use this oil for a natural glow.   TREMELLA MUSHROOM Tremella fuciformis is one of the great superfood mushrooms and longevity tonic herbs in Traditional Chinese medicine (TCM). It’s use dates back as far as 200 A.D. when it was including in one of the earliest TCM classics- the materia medica by "Shen Nong Ben Cao Jing”, the father of Chinese medicine. In ancient times, like many of the other revered medicinal mushrooms such as Reishi and Cordyceps sinensis, Tremella was only reserved for royalty, ruling family members or for rich people who could afford this highly valued superfood.   For centuries, Chinese women have been consuming Tremella in its whole mushroom form and as a mushroom extract to make their skin more moist, soft and pliable. Its recognized as one of the best tonic herbs to help maintain the health of the skin as the body ages.   Tremella mushroom belongs to the jelly fungus family and has many different names. In Chinese, it's called silver ear mushroom (pinyin: yín ěr), white wood-ear mushroom (pinyin: yín ěr), and in Japanese, it's called shiro kikurage which translates to “white tree jellyfish”. It's also commonly known as “snow fungus” and the “beauty mushroom”.   Dermatologist Dendy Engelman, the director of dermatologic surgery at Metropolitan Hospital in New York City, says the fungus acts similar to that of hydration powerhouse hyaluronic acid by pulling moisture to the skin. Hyaluronic acid can hold up to 1,000 times its weight in water, so finding an all-natural match for its hydrating power is pretty major. And snow mushroom has an extra edge. "The particles are smaller than hyaluronic acid so it penetrates the skin more easily," says Engelman.   Tremella mushroom has many restorative benefits but it's most famous for its beauty and skin enhancing properties:   Nourishes Skin Naturally Moisturizes When applied topically, Tremella generates a natural hydration film on the skin that can help relieve dryness, support overall skin health by balancing optimal hydration and enabling the skin to develop elasticity and appear more supple and full.  Improves Elasticity Tremella’s ability to absorb into the deeper layers of the skin works to enhance skin elasticity and helps plump & smooth out fine lines and wrinkles. Even better, Tremella also has an incredible ability to break down free radicals - which prevents fine lines and wrinkles from forming in the first place!  Slows Skin Aging Brightens Complexion Deeply Hydrates Inside and Out Boasts High Concentration of Vitamin D This mushroom also happens to be high in Vitamin D. When eaten, Tremella mushroom is the highest food source of the Vitamin D precursor, pro-vitamin D. When topically applied, Vitamin D has also shown impressive skin healing abilities. It helps cell growth, wound healing, and maintaining the barrier function of the skin. Basically, it’s like nature’s Band-Aid.  And now for a less-fun fact?Between the ages of 20-70, the skin’s natural ability to create Vitamin D decreases by 75%. This is why it's essential to support your skin with extra, high quality sources of Vitamin D such as Tremella.  The nutritional profile for Tremella includes: ∙ Protein and amino acids ∙ Enzymes ∙ Vitamins ∙ Minerals ∙ Polysaccharides ∙ Beta-Glucans ∙ Flavonoids ∙ Carotenoids ∙ Beta-Glucans ∙ Phenols and polyphenols ∙ Alkaloids ∙ Organic acids In addition to being a potent immune stimulant, one of nature’s richest sources of vitamin D and containing high levels of antioxidants, Tremella is brimming with medicinal properties, as you can see!   Celery Seed Extract The essential oil of celery seed is derived from the celery plant, scientifically known as Apium graveolens from the Umbelliferae plant family. Celery is not just a vegetable used for salads and stir-fries, but it is a revered herb to the Chinese as early as in the 5th century and is even widely used in the Indian Ayurvedic medicinal area.   Not only that, celery was held in high and sacred regard during the Greek era. In fact, it was believed that celery was used in the tomb of the famous Pharaoh Tutankhamun and mentioned in the works of the great and famous Roman encyclopaedist, Aulus Cornelius Celsus!   All these examples mentioned attest to the high medicinal value of celery and the essential oil derived from its plant, so let’s find out more about what celery seed essential oil can do to benefit our SKIN! Containing vitamins A, C, and K, celery extract is an antioxidant-rich ingredient that can help repel free radicals, ward off photoaging, and ensure continual cell turnover. Antioxidants are true powerhouses, both in skincare and in our diets – so suffice to say, we’re thrilled to introduce this potent ingredient in REVERSE!     Linseed Extract You've probably already heard of linseed oil which is often used in manufacturing paints and varnishes as well as inks for printing purposes. These days, it's being utilized in a lot of various products.   Did you know that the linseed extract which is expressed from the oil-rich seeds of the flax flower is also highly employed in the production of cosmetics and skincare items? This is because it's also been proven valuable for enhancing the skin's appearance and health.   Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Linseed extract is extremely high in omega-3 fatty acids, B vitamins, potassium, lecithin, magnesium, fiber, protein and zinc, which gives it strong anti-aging capabilities to reduce wrinkles and increase firmness. Three of the skin-altering conditions you can avoid if protected with linseed extract topically include; Inflammation, Aging, and Allergies     ROSE GERANIUM ESSENTIAL OIL A rose geranium is a type of geranium plant with leaves that smell strongly like roses. This species of geranium is native to certain parts of Africa.   It’s also called rose-scented geranium, sweet-scented geranium, or old-fashioned rose geranium. The plant has velvety, plush leaves and flowers that bloom pale pink or almost white.   A 2017 review of studies demonstrated that antioxidant properties in rose geranium oil may help reduce the signs of aging. The anti-inflammatory properties of rose geranium oil have been demonstrated in animal studies. In fact, one 2013 study showed rose geranium oil had a strong impact on reducing swelling in mice paws and ears. It suggested that rose geranium oil could be the basis of new anti-inflammatory drugs that may have less harmful side effects than current medications. Rose geranium oil has strong antimicrobial, antifungal, and antiviral properties. The food service industry even uses rose geranium oil as a natural preservative in some food products. In one 2017 review of studies, rose geranium was shown to reduce bacterial, fungi, and viruses that cause skin disease and infections.     RESOURCES   NEW! Organixx Skin’s – REVERSE Anti-Aging Serum https://shop.organixx.com/products/reverse-antiaging-serum?gl=5f19d0428ebf584f6d7b23c6   Organixx Skin’s – RESTORE Vitamin C Serum https://shop.organixx.com/products/restore-vitamin-c-serum?gl=5f19cf988ebf58b96e7b23c6   Organixx Skin’s – RENEW Eye Crème https://shop.organixx.com/products/renew-eye-cream?gl=5f19cf5e8ebf58f1677b23c7   Face Serum: Why You Should Use One https://www.paulaschoice.com/expert-advice/skincare-advice/anti-aging-wrinkles/why-you-should-consider-using-a-serum.html   Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics https://www.sciencedirect.com/science/article/pii/S0047637418300435   Body image, aging, and identity in women over 50: The Gender and Body Image (GABI) study https://www.tandfonline.com/doi/abs/10.1080/08952841.2015.1065140   Wikipedia https://en.wikipedia.org/wiki/Dermal_fibroblast   Human Dermal Fibroblasts (HDF) https://www.cellapplications.com/human-dermal-fibroblasts-hdf   The hallmarks of fibroblast aging. https://www.ncbi.nlm.nih.gov/pubmed/24686308   The effect of aging in primary human dermal fibroblasts https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219165   Skin ages when the main cells in the dermis lose their identity and function https://www.sciencedaily.com/releases/2018/11/181108134147.htm   Understanding Dermal Stem Cells  https://pdfs.semanticscholar.org/05d2/9b270ff706b3421eb5eaa12f154d0d882635.pdf   Activation of Mesenchymal Progenitor Cells to Correct Signs of Skin Aging http://tst.pg2.at/abstracts/data/full_papers/full_paper_19.pdf   School of Natural Skincare International https://www.schoolofnaturalskincare.com/6-reasons-to-use-raspberry-seed-oil-in-your-natural-skincare-products/   Characteristics of raspberry (Rubus idaeus L.) seed oil https://www.sciencedirect.com/science/article/pii/S0308814699002605   Cranberry Seed Oil – Unrefined http://www.ingredientstodiefor.com/item/Cranberry_Seed_Oil_Unrefined/1164   INGREDIENT SPOTLIGHT ON CRANBERRY SEED OIL https://jordansamuelskin.com/blogs/news/ingredient-spotlight-on-cranberry-seed-oil   Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils https://www.sciencedirect.com/science/article/pii/S0308814604005412   Cranberry seed oil extract and compositions containing components thereof – Patent https://patents.google.com/patent/US6641847B1/en   Ancient Beauty Secrets of Tremella Mushroom (For Flawless Skin) https://teelixir.com/blogs/news/ancient-beauty-secrets-tremella-mushroom   Medicinal Value of the Genus Tremella Pers. (Heterobasidiomycetes) (Review) http://www.dl.begellhouse.com/journals/708ae68d64b17c52,580b7b864183d53b,567a96af6caf987e.html   Mushroom Cosmetics: The Present and Future https://www.mdpi.com/2079-9284/3/3/22   Skin Wound Healing Promoting Effect of Polysaccharides Extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo Porcine Skin Wound Healing Model https://pdfs.semanticscholar.org/a84a/e79d2e3124440e80a7070c7770475485cb06.pdf   Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging https://www.sciencedirect.com/science/article/abs/pii/S175646461500554X   Pelargonium graveolens (Rose Geranium) – A Novel Therapeutic Agent for Antibacterial, Antioxidant, Antifungal and Diabetics https://www.acanceresearch.com/cancer-research/pelargonium-graveolens-rose-geranium--a-novel-therapeutic-agent-for-antibacterial-antioxidant-antifungal-and-diabetics.php?aid=18420   Rose geranium essential oil as a source of new and safe anti-inflammatory drugs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793238/   Rose Geranium Essential Oil as a Source of New and Safe Anti-Inflammatory Drugs https://pubmed.ncbi.nlm.nih.gov/24103319/       Subscribe to Empowering You Organically 
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Empowering You Organically - Audio Edition
This Anti-Aging Serum Breaks All the Rules

Empowering You Organically - Audio Edition

Play Episode Listen Later Feb 9, 2021 43:25


When Should You Start Using Anti-Aging Skin Care Products? The wealth of products available these days to target visible signs of aging such as fine lines, crow’s feet, dark under-eye circles and dull skin are a gift and a curse. The options are so extensive that it can actually feel quite overwhelming figuring out a skin care regimen that works best. So when and where does one begin?   Experts agree that skin starts to age around 20 years old and recommend that you start the road to prevention early. “I recommend my patients to start incorporating anti-aging skin care products in their 20s and 30s, when our skin slowly starts to lose collagen,” says Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City.   Face Serum Benefits for All Ages Just like it’s never too soon to start being physically active or eating mindfully, this fundamental aspect of life also applies to skin care. Using serums loaded with incredibly important ingredients before you start seeing signs of aging and environmental assault means you'll be on track for getting (and keeping) the beautiful skin you want now and in the long term.   Keep in mind that just like your body never "gets used" to eating nutrient-dense foods, nor does your skin get used to great ingredients. Your skin craves and needs generous amounts of beneficial ingredients like antioxidants, skin-replenishing, and skin-restoring ingredients because each group helps skin be healthy and stay young-looking. Using them now does not mean they won’t work "when you really need them"; rather, they will be working for you every day of your life.   Of course, these ingredients also work after signs of aging appear, but without question, sooner is better than later!     Roots of The Aging Concept Referring to Greek mythology, the quest for immortality is embodied in the story of Eos, the immortal goddess of dawn. She falls madly in love with Tithon, a mortal human. Not supporting the idea of seeing him die, she claims for him eternity. Zeus agrees, but poor Eos realizes her mistake too late, as what she wanted for Tithon was not eternity but eternal youth. She will therefore be condemned to see him eternally grow old. This myth of ancient Greece refers directly to the current perception of aging: accept the temporary nature of life, while differing as long as possible the appearance of the signs of aging.   Today, in industrialized countries, this quest seems strongly motivated by the fear of social exclusion. Indeed, a study conducted on a cohort of 1,713 American women, over 50 years old and mostly of Caucasian type, highlights a great psychological suffering based both on the image that these women have of themselves but also on the degrading image that the rest of society sends back to them.   More than 50% of these women reported the perception of physical changes that occur during aging, notably sagging skin and wrinkles. Their cognitive adaptations to the physical experience of aging and the psychological experience of body image altered in parallel. This point is extremely important because it shows how much women correlate the initiation of their aging-related psychological malaise with the appearance of visible signs revealing their age.    Let’s get scientific for a minute…   With age, our tissues lose their function and capacity to regenerate after being damaged. A study published today in Cell by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Centro Nacional de Análisis Genómico of the Center for Genomic Regulation (CNAG-CRG) explains how dermal fibroblasts age.   The main conclusion drawn is that these fibroblasts lose their cell identity, as if they had "forgotten" what they are, and consequently their activity is altered, thus affecting tissue. The study reveals the cellular and molecular pathways affected by aging and proposes that they could be manipulated to delay or even reverse the skin aging process.   The skin is the most exposed organ of the body, and it functions as a barrier against external aggressions. It frequently experiences the direct effects of environmental exposure, including UV radiation and air pollution. Alterations in skin structure and physiology occur as natural consequences of aging and contribute to diminished skin health. These damages can be aggravated by external factors and, combined with lifestyle, result in significant biological alterations, characteristic of premature aging.   A fibroblast is a type of cell that is responsible for making the extracellular matrix and collagen.   Fibroblasts are large, flat, elongated (spindle-shaped) cells possessing processes extending out from the ends of the cell body. ... Fibroblasts produce tropocollagen, which is the forerunner of collagen, and ground substance, an amorphous gel-like matrix that fills the spaces between cells and fibres in connective tissue.   Together, this extracellular matrix and collagen form the structural framework of tissues in animals and plays an important role in tissue repair. Fibroblasts are the main connective tissue cells present in the body.   Dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame.     Why the Science Lesson? Organixx Skin has released REVERSE our anti-aging serum! When we were experimenting with formulations and ingredients, we did our science homework. We wanted to provide you with a clean, healthy, and effective product that helps turn back the hands of time.   The synergy of the fresh, clean, and pure ingredients in REVERSE address the root cause of skin aging in the 21st century – the inside factors like diminished collagen production and aging dermal cells - as well as the outside factors like UV damage and environmental factors.   Let’s dive into each ingredient…   Croda Juvinity™  Visibly reduces the signs of aging on the face and décolleté. Smoothes wrinkles, restructures and densifies the dermis. Juvinity™ delays cell senescence. It limits oxidative stress and telomere shortening to ensure optimal metabolism and replication rate as a young cell. Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Reactivates the synthesis of major dermal constituents, preserves the cytoskeleton functionality and prolongs cell lifespan by maintaining telomere length.     ARGAN STEM CELLS Referred to as “liquid gold”, argan oil is fast-absorbing and known for increasing cell regeneration, reducing the appearance of fine lines and wrinkles. Argan oil is also rich in phenols and carotenes, antioxidants that protect the skin from aging free-radical damage.   Argan stem cells are well known for their anti-aging properties. They are regenerative and work to strengthen skin's elasticity.  Argan stem cells also penetrate the skin at a deeper level, so are able to help fight the signs of aging.   Argan stem cells are the only proven stem cells with the ability to penetrate the skin's dermis, meaning they can help protect and revitalize human dermal stem cells!     RASPBERRY SEED OIL Raspberry seed oil is rich in EFAs (essential fatty acids), primarily linoleic and linolenic acids. It contains very high levels of tocopherols (Vitamin E), which act as antioxidants, and carotenoids (Vitamin A).       Because of its composition, raspberry seed oil possesses superior anti-inflammatory qualities which makes it a nice addition to face, lip and sunscreen products.    Absorbs UV rays (Oomah et al., 2000) although its efficacy as a sunscreen has not yet been confirmed. Anti-inflammatory due to high content of alpha linolenic acid (the highest in any fruit seed oil) and phytosterols, therefore helpful for eczema and psoriasis. Very high in Vitamin E – an antioxidant. Antioxidants in skin care are important to prevent oxidative damage, which can lead to premature skin aging and skin cancer. Very high levels of phytosterols that can help reduce trans-epidermal water loss, thereby helping to keep skin moisturized. Phytosterols also help to repair skin damaged by environmental factors including sun damage. It’s a great source of alpha linolenic acid – an essential fatty acid that has regenerative and anti-aging skin benefits. Red raspberry seed oil also has a low comedogenic rating of 0-1, meaning it’s not likely to clog pores.   CRANBERRY SEED OIL Cranberry Seed Oil, cold pressed from the seed of the super fruit, is unique among the fixed oils because it contains a very high essential fatty acid profile, along with a good mixed tocopherols and tocotrienols (vitamin E) content, high phytosterols, and a 1:1 ratio of omega 3 to omega 6 essential fatty acids which gives it excellent anti-oxidant activity and skin nurturing benefits.   Cranberry Seed Oil contains one of the highest antioxidants and phytosterols content of any of the vegetable / fruit oils, making it an excellent addition to your natural sun protection products where it will help to prevent photo damage.   Anti-oxidants that are consumed can reach the skin but, with free radical damage being the heaviest assault on the skin, and the cause of almost all of the signs of aging and unhealthy skin, it is beneficial to apply them topically where their protection can go to work immediately.   Antioxidant Protection Skin Conditioning and Restructuring Vitamins A, C, E, and K Enhanced Cellular Function Aids in the Skin's Absorption, and Utilization, of Essential Fatty Acids Cranberry seed oil has the perfect ratio of omega-3 to omega-6 fatty acids, meaning it will absorb into your skin very well. Exceptional Skin Moisturizer Skin Tightening Activity Natural brightener. If your face is looking a little on the dull side, use this oil for a natural glow.   TREMELLA MUSHROOM Tremella fuciformis is one of the great superfood mushrooms and longevity tonic herbs in Traditional Chinese medicine (TCM). It’s use dates back as far as 200 A.D. when it was including in one of the earliest TCM classics- the materia medica by "Shen Nong Ben Cao Jing”, the father of Chinese medicine. In ancient times, like many of the other revered medicinal mushrooms such as Reishi and Cordyceps sinensis, Tremella was only reserved for royalty, ruling family members or for rich people who could afford this highly valued superfood.   For centuries, Chinese women have been consuming Tremella in its whole mushroom form and as a mushroom extract to make their skin more moist, soft and pliable. Its recognized as one of the best tonic herbs to help maintain the health of the skin as the body ages.   Tremella mushroom belongs to the jelly fungus family and has many different names. In Chinese, it's called silver ear mushroom (pinyin: yín ěr), white wood-ear mushroom (pinyin: yín ěr), and in Japanese, it's called shiro kikurage which translates to “white tree jellyfish”. It's also commonly known as “snow fungus” and the “beauty mushroom”.   Dermatologist Dendy Engelman, the director of dermatologic surgery at Metropolitan Hospital in New York City, says the fungus acts similar to that of hydration powerhouse hyaluronic acid by pulling moisture to the skin. Hyaluronic acid can hold up to 1,000 times its weight in water, so finding an all-natural match for its hydrating power is pretty major. And snow mushroom has an extra edge. "The particles are smaller than hyaluronic acid so it penetrates the skin more easily," says Engelman.   Tremella mushroom has many restorative benefits but it's most famous for its beauty and skin enhancing properties:   Nourishes Skin Naturally Moisturizes When applied topically, Tremella generates a natural hydration film on the skin that can help relieve dryness, support overall skin health by balancing optimal hydration and enabling the skin to develop elasticity and appear more supple and full.  Improves Elasticity Tremella’s ability to absorb into the deeper layers of the skin works to enhance skin elasticity and helps plump & smooth out fine lines and wrinkles. Even better, Tremella also has an incredible ability to break down free radicals - which prevents fine lines and wrinkles from forming in the first place!  Slows Skin Aging Brightens Complexion Deeply Hydrates Inside and Out Boasts High Concentration of Vitamin D This mushroom also happens to be high in Vitamin D. When eaten, Tremella mushroom is the highest food source of the Vitamin D precursor, pro-vitamin D. When topically applied, Vitamin D has also shown impressive skin healing abilities. It helps cell growth, wound healing, and maintaining the barrier function of the skin. Basically, it’s like nature’s Band-Aid.  And now for a less-fun fact?Between the ages of 20-70, the skin’s natural ability to create Vitamin D decreases by 75%. This is why it's essential to support your skin with extra, high quality sources of Vitamin D such as Tremella.  The nutritional profile for Tremella includes: ∙ Protein and amino acids ∙ Enzymes ∙ Vitamins ∙ Minerals ∙ Polysaccharides ∙ Beta-Glucans ∙ Flavonoids ∙ Carotenoids ∙ Beta-Glucans ∙ Phenols and polyphenols ∙ Alkaloids ∙ Organic acids In addition to being a potent immune stimulant, one of nature’s richest sources of vitamin D and containing high levels of antioxidants, Tremella is brimming with medicinal properties, as you can see!   Celery Seed Extract The essential oil of celery seed is derived from the celery plant, scientifically known as Apium graveolens from the Umbelliferae plant family. Celery is not just a vegetable used for salads and stir-fries, but it is a revered herb to the Chinese as early as in the 5th century and is even widely used in the Indian Ayurvedic medicinal area.   Not only that, celery was held in high and sacred regard during the Greek era. In fact, it was believed that celery was used in the tomb of the famous Pharaoh Tutankhamun and mentioned in the works of the great and famous Roman encyclopaedist, Aulus Cornelius Celsus!   All these examples mentioned attest to the high medicinal value of celery and the essential oil derived from its plant, so let’s find out more about what celery seed essential oil can do to benefit our SKIN! Containing vitamins A, C, and K, celery extract is an antioxidant-rich ingredient that can help repel free radicals, ward off photoaging, and ensure continual cell turnover. Antioxidants are true powerhouses, both in skincare and in our diets – so suffice to say, we’re thrilled to introduce this potent ingredient in REVERSE!     Linseed Extract You've probably already heard of linseed oil which is often used in manufacturing paints and varnishes as well as inks for printing purposes. These days, it's being utilized in a lot of various products.   Did you know that the linseed extract which is expressed from the oil-rich seeds of the flax flower is also highly employed in the production of cosmetics and skincare items? This is because it's also been proven valuable for enhancing the skin's appearance and health.   Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Linseed extract is extremely high in omega-3 fatty acids, B vitamins, potassium, lecithin, magnesium, fiber, protein and zinc, which gives it strong anti-aging capabilities to reduce wrinkles and increase firmness. Three of the skin-altering conditions you can avoid if protected with linseed extract topically include; Inflammation, Aging, and Allergies     ROSE GERANIUM ESSENTIAL OIL A rose geranium is a type of geranium plant with leaves that smell strongly like roses. This species of geranium is native to certain parts of Africa.   It’s also called rose-scented geranium, sweet-scented geranium, or old-fashioned rose geranium. The plant has velvety, plush leaves and flowers that bloom pale pink or almost white.   A 2017 review of studies demonstrated that antioxidant properties in rose geranium oil may help reduce the signs of aging. The anti-inflammatory properties of rose geranium oil have been demonstrated in animal studies. In fact, one 2013 study showed rose geranium oil had a strong impact on reducing swelling in mice paws and ears. It suggested that rose geranium oil could be the basis of new anti-inflammatory drugs that may have less harmful side effects than current medications. Rose geranium oil has strong antimicrobial, antifungal, and antiviral properties. The food service industry even uses rose geranium oil as a natural preservative in some food products. In one 2017 review of studies, rose geranium was shown to reduce bacterial, fungi, and viruses that cause skin disease and infections.     RESOURCES   NEW! Organixx Skin’s – REVERSE Anti-Aging Serum https://shop.organixx.com/products/reverse-antiaging-serum?gl=5f19d0428ebf584f6d7b23c6   Organixx Skin’s – RESTORE Vitamin C Serum https://shop.organixx.com/products/restore-vitamin-c-serum?gl=5f19cf988ebf58b96e7b23c6   Organixx Skin’s – RENEW Eye Crème https://shop.organixx.com/products/renew-eye-cream?gl=5f19cf5e8ebf58f1677b23c7   Face Serum: Why You Should Use One https://www.paulaschoice.com/expert-advice/skincare-advice/anti-aging-wrinkles/why-you-should-consider-using-a-serum.html   Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics https://www.sciencedirect.com/science/article/pii/S0047637418300435   Body image, aging, and identity in women over 50: The Gender and Body Image (GABI) study https://www.tandfonline.com/doi/abs/10.1080/08952841.2015.1065140   Wikipedia https://en.wikipedia.org/wiki/Dermal_fibroblast   Human Dermal Fibroblasts (HDF) https://www.cellapplications.com/human-dermal-fibroblasts-hdf   The hallmarks of fibroblast aging. https://www.ncbi.nlm.nih.gov/pubmed/24686308   The effect of aging in primary human dermal fibroblasts https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219165   Skin ages when the main cells in the dermis lose their identity and function https://www.sciencedaily.com/releases/2018/11/181108134147.htm   Understanding Dermal Stem Cells  https://pdfs.semanticscholar.org/05d2/9b270ff706b3421eb5eaa12f154d0d882635.pdf   Activation of Mesenchymal Progenitor Cells to Correct Signs of Skin Aging http://tst.pg2.at/abstracts/data/full_papers/full_paper_19.pdf   School of Natural Skincare International https://www.schoolofnaturalskincare.com/6-reasons-to-use-raspberry-seed-oil-in-your-natural-skincare-products/   Characteristics of raspberry (Rubus idaeus L.) seed oil https://www.sciencedirect.com/science/article/pii/S0308814699002605   Cranberry Seed Oil – Unrefined http://www.ingredientstodiefor.com/item/Cranberry_Seed_Oil_Unrefined/1164   INGREDIENT SPOTLIGHT ON CRANBERRY SEED OIL https://jordansamuelskin.com/blogs/news/ingredient-spotlight-on-cranberry-seed-oil   Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils https://www.sciencedirect.com/science/article/pii/S0308814604005412   Cranberry seed oil extract and compositions containing components thereof – Patent https://patents.google.com/patent/US6641847B1/en   Ancient Beauty Secrets of Tremella Mushroom (For Flawless Skin) https://teelixir.com/blogs/news/ancient-beauty-secrets-tremella-mushroom   Medicinal Value of the Genus Tremella Pers. (Heterobasidiomycetes) (Review) http://www.dl.begellhouse.com/journals/708ae68d64b17c52,580b7b864183d53b,567a96af6caf987e.html   Mushroom Cosmetics: The Present and Future https://www.mdpi.com/2079-9284/3/3/22   Skin Wound Healing Promoting Effect of Polysaccharides Extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo Porcine Skin Wound Healing Model https://pdfs.semanticscholar.org/a84a/e79d2e3124440e80a7070c7770475485cb06.pdf   Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging https://www.sciencedirect.com/science/article/abs/pii/S175646461500554X   Pelargonium graveolens (Rose Geranium) – A Novel Therapeutic Agent for Antibacterial, Antioxidant, Antifungal and Diabetics https://www.acanceresearch.com/cancer-research/pelargonium-graveolens-rose-geranium--a-novel-therapeutic-agent-for-antibacterial-antioxidant-antifungal-and-diabetics.php?aid=18420   Rose geranium essential oil as a source of new and safe anti-inflammatory drugs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793238/   Rose Geranium Essential Oil as a Source of New and Safe Anti-Inflammatory Drugs https://pubmed.ncbi.nlm.nih.gov/24103319/       Subscribe to Empowering You Organically 
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Herbal Marie
Herb Nerd Word: ANTIFUNGAL

Herbal Marie

Play Episode Listen Later Oct 3, 2020 11:01


Antifungal. https://herbalmarie.blogspot.com/p/nerdy-words.html?m=1 --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/herbalmarie/message

The Internet Book of Critical Care Podcast
IBCC Episode 98 - Antifungal Agents

The Internet Book of Critical Care Podcast

Play Episode Listen Later Sep 14, 2020 25:00


In this episode we simplify the approach to covering your invasive fungal infections in critically unwell patients.  Yeast vs Mold vs Endemic Mycoses Azoles vs Echinocandins vs Amphotericin

Empowering You Organically - Audio Edition
New Anti-Aging Serum Breaks All the Rules

Empowering You Organically - Audio Edition

Play Episode Listen Later Aug 3, 2020 43:31


When Should You Start Using Anti-Aging Skin Care Products? The wealth of products available these days to target visible signs of aging such as fine lines, crow’s feet, dark under-eye circles and dull skin are a gift and a curse. The options are so extensive that it can actually feel quite overwhelming figuring out a skin care regimen that works best. So when and where does one begin?   Experts agree that skin starts to age around 20 years old and recommend that you start the road to prevention early. “I recommend my patients to start incorporating anti-aging skin care products in their 20s and 30s, when our skin slowly starts to lose collagen,” says Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City.   Face Serum Benefits for All Ages Just like it’s never too soon to start being physically active or eating mindfully, this fundamental aspect of life also applies to skin care. Using serums loaded with incredibly important ingredients before you start seeing signs of aging and environmental assault means you'll be on track for getting (and keeping) the beautiful skin you want now and in the long term.   Keep in mind that just like your body never "gets used" to eating nutrient-dense foods, nor does your skin get used to great ingredients. Your skin craves and needs generous amounts of beneficial ingredients like antioxidants, skin-replenishing, and skin-restoring ingredients because each group helps skin be healthy and stay young-looking. Using them now does not mean they won’t work "when you really need them"; rather, they will be working for you every day of your life.   Of course, these ingredients also work after signs of aging appear, but without question, sooner is better than later!     Roots of The Aging Concept Referring to Greek mythology, the quest for immortality is embodied in the story of Eos, the immortal goddess of dawn. She falls madly in love with Tithon, a mortal human. Not supporting the idea of seeing him die, she claims for him eternity. Zeus agrees, but poor Eos realizes her mistake too late, as what she wanted for Tithon was not eternity but eternal youth. She will therefore be condemned to see him eternally grow old. This myth of ancient Greece refers directly to the current perception of aging: accept the temporary nature of life, while differing as long as possible the appearance of the signs of aging.   Today, in industrialized countries, this quest seems strongly motivated by the fear of social exclusion. Indeed, a study conducted on a cohort of 1,713 American women, over 50 years old and mostly of Caucasian type, highlights a great psychological suffering based both on the image that these women have of themselves but also on the degrading image that the rest of society sends back to them.   More than 50% of these women reported the perception of physical changes that occur during aging, notably sagging skin and wrinkles. Their cognitive adaptations to the physical experience of aging and the psychological experience of body image altered in parallel. This point is extremely important because it shows how much women correlate the initiation of their aging-related psychological malaise with the appearance of visible signs revealing their age.    Let’s get scientific for a minute…   With age, our tissues lose their function and capacity to regenerate after being damaged. A study published today in Cell by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Centro Nacional de Análisis Genómico of the Center for Genomic Regulation (CNAG-CRG) explains how dermal fibroblasts age.   The main conclusion drawn is that these fibroblasts lose their cell identity, as if they had "forgotten" what they are, and consequently their activity is altered, thus affecting tissue. The study reveals the cellular and molecular pathways affected by aging and proposes that they could be manipulated to delay or even reverse the skin aging process.   The skin is the most exposed organ of the body, and it functions as a barrier against external aggressions. It frequently experiences the direct effects of environmental exposure, including UV radiation and air pollution. Alterations in skin structure and physiology occur as natural consequences of aging and contribute to diminished skin health. These damages can be aggravated by external factors and, combined with lifestyle, result in significant biological alterations, characteristic of premature aging.   A fibroblast is a type of cell that is responsible for making the extracellular matrix and collagen.   Fibroblasts are large, flat, elongated (spindle-shaped) cells possessing processes extending out from the ends of the cell body. ... Fibroblasts produce tropocollagen, which is the forerunner of collagen, and ground substance, an amorphous gel-like matrix that fills the spaces between cells and fibres in connective tissue.   Together, this extracellular matrix and collagen form the structural framework of tissues in animals and plays an important role in tissue repair. Fibroblasts are the main connective tissue cells present in the body.   Dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame.     Why the Science Lesson? Organixx Skin has released REVERSE our anti-aging serum! When we were experimenting with formulations and ingredients, we did our science homework. We wanted to provide you with a clean, healthy, and effective product that helps turn back the hands of time.   The synergy of the fresh, clean, and pure ingredients in REVERSE address the root cause of skin aging in the 21st century – the inside factors like diminished collagen production and aging dermal cells - as well as the outside factors like UV damage and environmental factors.   Let’s dive into each ingredient…   Croda Juvinity™  Visibly reduces the signs of aging on the face and décolleté. Smoothes wrinkles, restructures and densifies the dermis. Juvinity™ delays cell senescence. It limits oxidative stress and telomere shortening to ensure optimal metabolism and replication rate as a young cell. Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Reactivates the synthesis of major dermal constituents, preserves the cytoskeleton functionality and prolongs cell lifespan by maintaining telomere length.     ARGAN STEM CELLS Referred to as “liquid gold”, argan oil is fast-absorbing and known for increasing cell regeneration, reducing the appearance of fine lines and wrinkles. Argan oil is also rich in phenols and carotenes, antioxidants that protect the skin from aging free-radical damage.   Argan stem cells are well known for their anti-aging properties. They are regenerative and work to strengthen skin's elasticity.  Argan stem cells also penetrate the skin at a deeper level, so are able to help fight the signs of aging.   Argan stem cells are the only proven stem cells with the ability to penetrate the skin's dermis, meaning they can help protect and revitalize human dermal stem cells!     RASPBERRY SEED OIL Raspberry seed oil is rich in EFAs (essential fatty acids), primarily linoleic and linolenic acids. It contains very high levels of tocopherols (Vitamin E), which act as antioxidants, and carotenoids (Vitamin A).       Because of its composition, raspberry seed oil possesses superior anti-inflammatory qualities which makes it a nice addition to face, lip and sunscreen products.    Absorbs UV rays (Oomah et al., 2000) although its efficacy as a sunscreen has not yet been confirmed. Anti-inflammatory due to high content of alpha linolenic acid (the highest in any fruit seed oil) and phytosterols, therefore helpful for eczema and psoriasis. Very high in Vitamin E – an antioxidant. Antioxidants in skin care are important to prevent oxidative damage, which can lead to premature skin aging and skin cancer. Very high levels of phytosterols that can help reduce trans-epidermal water loss, thereby helping to keep skin moisturized. Phytosterols also help to repair skin damaged by environmental factors including sun damage. It’s a great source of alpha linolenic acid – an essential fatty acid that has regenerative and anti-aging skin benefits. Red raspberry seed oil also has a low comedogenic rating of 0-1, meaning it’s not likely to clog pores.   CRANBERRY SEED OIL Cranberry Seed Oil, cold pressed from the seed of the super fruit, is unique among the fixed oils because it contains a very high essential fatty acid profile, along with a good mixed tocopherols and tocotrienols (vitamin E) content, high phytosterols, and a 1:1 ratio of omega 3 to omega 6 essential fatty acids which gives it excellent anti-oxidant activity and skin nurturing benefits.   Cranberry Seed Oil contains one of the highest antioxidants and phytosterols content of any of the vegetable / fruit oils, making it an excellent addition to your natural sun protection products where it will help to prevent photo damage.   Anti-oxidants that are consumed can reach the skin but, with free radical damage being the heaviest assault on the skin, and the cause of almost all of the signs of aging and unhealthy skin, it is beneficial to apply them topically where their protection can go to work immediately.   Antioxidant Protection Skin Conditioning and Restructuring Vitamins A, C, E, and K Enhanced Cellular Function Aids in the Skin's Absorption, and Utilization, of Essential Fatty Acids Cranberry seed oil has the perfect ratio of omega-3 to omega-6 fatty acids, meaning it will absorb into your skin very well. Exceptional Skin Moisturizer Skin Tightening Activity Natural brightener. If your face is looking a little on the dull side, use this oil for a natural glow.   TREMELLA MUSHROOM Tremella fuciformis is one of the great superfood mushrooms and longevity tonic herbs in Traditional Chinese medicine (TCM). It’s use dates back as far as 200 A.D. when it was including in one of the earliest TCM classics- the materia medica by "Shen Nong Ben Cao Jing”, the father of Chinese medicine. In ancient times, like many of the other revered medicinal mushrooms such as Reishi and Cordyceps sinensis, Tremella was only reserved for royalty, ruling family members or for rich people who could afford this highly valued superfood.   For centuries, Chinese women have been consuming Tremella in its whole mushroom form and as a mushroom extract to make their skin more moist, soft and pliable. Its recognized as one of the best tonic herbs to help maintain the health of the skin as the body ages.   Tremella mushroom belongs to the jelly fungus family and has many different names. In Chinese, it's called silver ear mushroom (pinyin: yín ěr), white wood-ear mushroom (pinyin: yín ěr), and in Japanese, it's called shiro kikurage which translates to “white tree jellyfish”. It's also commonly known as “snow fungus” and the “beauty mushroom”.   Dermatologist Dendy Engelman, the director of dermatologic surgery at Metropolitan Hospital in New York City, says the fungus acts similar to that of hydration powerhouse hyaluronic acid by pulling moisture to the skin. Hyaluronic acid can hold up to 1,000 times its weight in water, so finding an all-natural match for its hydrating power is pretty major. And snow mushroom has an extra edge. "The particles are smaller than hyaluronic acid so it penetrates the skin more easily," says Engelman.   Tremella mushroom has many restorative benefits but it's most famous for its beauty and skin enhancing properties:   Nourishes Skin Naturally Moisturizes When applied topically, Tremella generates a natural hydration film on the skin that can help relieve dryness, support overall skin health by balancing optimal hydration and enabling the skin to develop elasticity and appear more supple and full.  Improves Elasticity Tremella’s ability to absorb into the deeper layers of the skin works to enhance skin elasticity and helps plump & smooth out fine lines and wrinkles. Even better, Tremella also has an incredible ability to break down free radicals - which prevents fine lines and wrinkles from forming in the first place!  Slows Skin Aging Brightens Complexion Deeply Hydrates Inside and Out Boasts High Concentration of Vitamin D This mushroom also happens to be high in Vitamin D. When eaten, Tremella mushroom is the highest food source of the Vitamin D precursor, pro-vitamin D. When topically applied, Vitamin D has also shown impressive skin healing abilities. It helps cell growth, wound healing, and maintaining the barrier function of the skin. Basically, it’s like nature’s Band-Aid.  And now for a less-fun fact?Between the ages of 20-70, the skin’s natural ability to create Vitamin D decreases by 75%. This is why it's essential to support your skin with extra, high quality sources of Vitamin D such as Tremella.  The nutritional profile for Tremella includes: ∙ Protein and amino acids ∙ Enzymes ∙ Vitamins ∙ Minerals ∙ Polysaccharides ∙ Beta-Glucans ∙ Flavonoids ∙ Carotenoids ∙ Beta-Glucans ∙ Phenols and polyphenols ∙ Alkaloids ∙ Organic acids In addition to being a potent immune stimulant, one of nature’s richest sources of vitamin D and containing high levels of antioxidants, Tremella is brimming with medicinal properties, as you can see!   Celery Seed Extract The essential oil of celery seed is derived from the celery plant, scientifically known as Apium graveolens from the Umbelliferae plant family. Celery is not just a vegetable used for salads and stir-fries, but it is a revered herb to the Chinese as early as in the 5th century and is even widely used in the Indian Ayurvedic medicinal area.   Not only that, celery was held in high and sacred regard during the Greek era. In fact, it was believed that celery was used in the tomb of the famous Pharaoh Tutankhamun and mentioned in the works of the great and famous Roman encyclopaedist, Aulus Cornelius Celsus!   All these examples mentioned attest to the high medicinal value of celery and the essential oil derived from its plant, so let’s find out more about what celery seed essential oil can do to benefit our SKIN! Containing vitamins A, C, and K, celery extract is an antioxidant-rich ingredient that can help repel free radicals, ward off photoaging, and ensure continual cell turnover. Antioxidants are true powerhouses, both in skincare and in our diets – so suffice to say, we’re thrilled to introduce this potent ingredient in REVERSE!     Linseed Extract You've probably already heard of linseed oil which is often used in manufacturing paints and varnishes as well as inks for printing purposes. These days, it's being utilized in a lot of various products.   Did you know that the linseed extract which is expressed from the oil-rich seeds of the flax flower is also highly employed in the production of cosmetics and skincare items? This is because it's also been proven valuable for enhancing the skin's appearance and health.   Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Linseed extract is extremely high in omega-3 fatty acids, B vitamins, potassium, lecithin, magnesium, fiber, protein and zinc, which gives it strong anti-aging capabilities to reduce wrinkles and increase firmness. Three of the skin-altering conditions you can avoid if protected with linseed extract topically include; Inflammation, Aging, and Allergies     ROSE GERANIUM ESSENTIAL OIL A rose geranium is a type of geranium plant with leaves that smell strongly like roses. This species of geranium is native to certain parts of Africa.   It’s also called rose-scented geranium, sweet-scented geranium, or old-fashioned rose geranium. The plant has velvety, plush leaves and flowers that bloom pale pink or almost white.   A 2017 review of studies demonstrated that antioxidant properties in rose geranium oil may help reduce the signs of aging. The anti-inflammatory properties of rose geranium oil have been demonstrated in animal studies. In fact, one 2013 study showed rose geranium oil had a strong impact on reducing swelling in mice paws and ears. It suggested that rose geranium oil could be the basis of new anti-inflammatory drugs that may have less harmful side effects than current medications. Rose geranium oil has strong antimicrobial, antifungal, and antiviral properties. The food service industry even uses rose geranium oil as a natural preservative in some food products. In one 2017 review of studies, rose geranium was shown to reduce bacterial, fungi, and viruses that cause skin disease and infections.     RESOURCES   NEW! Organixx Skin’s – REVERSE Anti-Aging Serum https://shop.organixx.com/products/reverse-antiaging-serum?gl=5f19d0428ebf584f6d7b23c6   Organixx Skin’s – RESTORE Vitamin C Serum https://shop.organixx.com/products/restore-vitamin-c-serum?gl=5f19cf988ebf58b96e7b23c6   Organixx Skin’s – RENEW Eye Crème https://shop.organixx.com/products/renew-eye-cream?gl=5f19cf5e8ebf58f1677b23c7   Face Serum: Why You Should Use One https://www.paulaschoice.com/expert-advice/skincare-advice/anti-aging-wrinkles/why-you-should-consider-using-a-serum.html   Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics https://www.sciencedirect.com/science/article/pii/S0047637418300435   Body image, aging, and identity in women over 50: The Gender and Body Image (GABI) study https://www.tandfonline.com/doi/abs/10.1080/08952841.2015.1065140   Wikipedia https://en.wikipedia.org/wiki/Dermal_fibroblast   Human Dermal Fibroblasts (HDF) https://www.cellapplications.com/human-dermal-fibroblasts-hdf   The hallmarks of fibroblast aging. https://www.ncbi.nlm.nih.gov/pubmed/24686308   The effect of aging in primary human dermal fibroblasts https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219165   Skin ages when the main cells in the dermis lose their identity and function https://www.sciencedaily.com/releases/2018/11/181108134147.htm   Understanding Dermal Stem Cells  https://pdfs.semanticscholar.org/05d2/9b270ff706b3421eb5eaa12f154d0d882635.pdf   Activation of Mesenchymal Progenitor Cells to Correct Signs of Skin Aging http://tst.pg2.at/abstracts/data/full_papers/full_paper_19.pdf   School of Natural Skincare International https://www.schoolofnaturalskincare.com/6-reasons-to-use-raspberry-seed-oil-in-your-natural-skincare-products/   Characteristics of raspberry (Rubus idaeus L.) seed oil https://www.sciencedirect.com/science/article/pii/S0308814699002605   Cranberry Seed Oil – Unrefined http://www.ingredientstodiefor.com/item/Cranberry_Seed_Oil_Unrefined/1164   INGREDIENT SPOTLIGHT ON CRANBERRY SEED OIL https://jordansamuelskin.com/blogs/news/ingredient-spotlight-on-cranberry-seed-oil   Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils https://www.sciencedirect.com/science/article/pii/S0308814604005412   Cranberry seed oil extract and compositions containing components thereof – Patent https://patents.google.com/patent/US6641847B1/en   Ancient Beauty Secrets of Tremella Mushroom (For Flawless Skin) https://teelixir.com/blogs/news/ancient-beauty-secrets-tremella-mushroom   Medicinal Value of the Genus Tremella Pers. (Heterobasidiomycetes) (Review) http://www.dl.begellhouse.com/journals/708ae68d64b17c52,580b7b864183d53b,567a96af6caf987e.html   Mushroom Cosmetics: The Present and Future https://www.mdpi.com/2079-9284/3/3/22   Skin Wound Healing Promoting Effect of Polysaccharides Extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo Porcine Skin Wound Healing Model https://pdfs.semanticscholar.org/a84a/e79d2e3124440e80a7070c7770475485cb06.pdf   Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging https://www.sciencedirect.com/science/article/abs/pii/S175646461500554X   Pelargonium graveolens (Rose Geranium) – A Novel Therapeutic Agent for Antibacterial, Antioxidant, Antifungal and Diabetics https://www.acanceresearch.com/cancer-research/pelargonium-graveolens-rose-geranium--a-novel-therapeutic-agent-for-antibacterial-antioxidant-antifungal-and-diabetics.php?aid=18420   Rose geranium essential oil as a source of new and safe anti-inflammatory drugs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793238/   Rose Geranium Essential Oil as a Source of New and Safe Anti-Inflammatory Drugs https://pubmed.ncbi.nlm.nih.gov/24103319/   Subscribe to Empowering You Organically 
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Empowering You Organically - Video Edition
New Anti-Aging Serum Breaks All the Rules

Empowering You Organically - Video Edition

Play Episode Listen Later Aug 3, 2020 43:31


When Should You Start Using Anti-Aging Skin Care Products? The wealth of products available these days to target visible signs of aging such as fine lines, crow’s feet, dark under-eye circles and dull skin are a gift and a curse. The options are so extensive that it can actually feel quite overwhelming figuring out a skin care regimen that works best. So when and where does one begin?   Experts agree that skin starts to age around 20 years old and recommend that you start the road to prevention early. “I recommend my patients to start incorporating anti-aging skin care products in their 20s and 30s, when our skin slowly starts to lose collagen,” says Y. Claire Chang, a board-certified cosmetic dermatologist at Union Square Laser Dermatology in New York City.   Face Serum Benefits for All Ages Just like it’s never too soon to start being physically active or eating mindfully, this fundamental aspect of life also applies to skin care. Using serums loaded with incredibly important ingredients before you start seeing signs of aging and environmental assault means you'll be on track for getting (and keeping) the beautiful skin you want now and in the long term.   Keep in mind that just like your body never "gets used" to eating nutrient-dense foods, nor does your skin get used to great ingredients. Your skin craves and needs generous amounts of beneficial ingredients like antioxidants, skin-replenishing, and skin-restoring ingredients because each group helps skin be healthy and stay young-looking. Using them now does not mean they won’t work "when you really need them"; rather, they will be working for you every day of your life.   Of course, these ingredients also work after signs of aging appear, but without question, sooner is better than later!     Roots of The Aging Concept Referring to Greek mythology, the quest for immortality is embodied in the story of Eos, the immortal goddess of dawn. She falls madly in love with Tithon, a mortal human. Not supporting the idea of seeing him die, she claims for him eternity. Zeus agrees, but poor Eos realizes her mistake too late, as what she wanted for Tithon was not eternity but eternal youth. She will therefore be condemned to see him eternally grow old. This myth of ancient Greece refers directly to the current perception of aging: accept the temporary nature of life, while differing as long as possible the appearance of the signs of aging.   Today, in industrialized countries, this quest seems strongly motivated by the fear of social exclusion. Indeed, a study conducted on a cohort of 1,713 American women, over 50 years old and mostly of Caucasian type, highlights a great psychological suffering based both on the image that these women have of themselves but also on the degrading image that the rest of society sends back to them.   More than 50% of these women reported the perception of physical changes that occur during aging, notably sagging skin and wrinkles. Their cognitive adaptations to the physical experience of aging and the psychological experience of body image altered in parallel. This point is extremely important because it shows how much women correlate the initiation of their aging-related psychological malaise with the appearance of visible signs revealing their age.    Let’s get scientific for a minute…   With age, our tissues lose their function and capacity to regenerate after being damaged. A study published today in Cell by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Centro Nacional de Análisis Genómico of the Center for Genomic Regulation (CNAG-CRG) explains how dermal fibroblasts age.   The main conclusion drawn is that these fibroblasts lose their cell identity, as if they had "forgotten" what they are, and consequently their activity is altered, thus affecting tissue. The study reveals the cellular and molecular pathways affected by aging and proposes that they could be manipulated to delay or even reverse the skin aging process.   The skin is the most exposed organ of the body, and it functions as a barrier against external aggressions. It frequently experiences the direct effects of environmental exposure, including UV radiation and air pollution. Alterations in skin structure and physiology occur as natural consequences of aging and contribute to diminished skin health. These damages can be aggravated by external factors and, combined with lifestyle, result in significant biological alterations, characteristic of premature aging.   A fibroblast is a type of cell that is responsible for making the extracellular matrix and collagen.   Fibroblasts are large, flat, elongated (spindle-shaped) cells possessing processes extending out from the ends of the cell body. ... Fibroblasts produce tropocollagen, which is the forerunner of collagen, and ground substance, an amorphous gel-like matrix that fills the spaces between cells and fibres in connective tissue.   Together, this extracellular matrix and collagen form the structural framework of tissues in animals and plays an important role in tissue repair. Fibroblasts are the main connective tissue cells present in the body.   Dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame.     Why the Science Lesson? Organixx Skin has released REVERSE our anti-aging serum! When we were experimenting with formulations and ingredients, we did our science homework. We wanted to provide you with a clean, healthy, and effective product that helps turn back the hands of time.   The synergy of the fresh, clean, and pure ingredients in REVERSE address the root cause of skin aging in the 21st century – the inside factors like diminished collagen production and aging dermal cells - as well as the outside factors like UV damage and environmental factors.   Let’s dive into each ingredient…   Croda Juvinity™  Visibly reduces the signs of aging on the face and décolleté. Smoothes wrinkles, restructures and densifies the dermis. Juvinity™ delays cell senescence. It limits oxidative stress and telomere shortening to ensure optimal metabolism and replication rate as a young cell. Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Reactivates the synthesis of major dermal constituents, preserves the cytoskeleton functionality and prolongs cell lifespan by maintaining telomere length.     ARGAN STEM CELLS Referred to as “liquid gold”, argan oil is fast-absorbing and known for increasing cell regeneration, reducing the appearance of fine lines and wrinkles. Argan oil is also rich in phenols and carotenes, antioxidants that protect the skin from aging free-radical damage.   Argan stem cells are well known for their anti-aging properties. They are regenerative and work to strengthen skin's elasticity.  Argan stem cells also penetrate the skin at a deeper level, so are able to help fight the signs of aging.   Argan stem cells are the only proven stem cells with the ability to penetrate the skin's dermis, meaning they can help protect and revitalize human dermal stem cells!     RASPBERRY SEED OIL Raspberry seed oil is rich in EFAs (essential fatty acids), primarily linoleic and linolenic acids. It contains very high levels of tocopherols (Vitamin E), which act as antioxidants, and carotenoids (Vitamin A).       Because of its composition, raspberry seed oil possesses superior anti-inflammatory qualities which makes it a nice addition to face, lip and sunscreen products.    Absorbs UV rays (Oomah et al., 2000) although its efficacy as a sunscreen has not yet been confirmed. Anti-inflammatory due to high content of alpha linolenic acid (the highest in any fruit seed oil) and phytosterols, therefore helpful for eczema and psoriasis. Very high in Vitamin E – an antioxidant. Antioxidants in skin care are important to prevent oxidative damage, which can lead to premature skin aging and skin cancer. Very high levels of phytosterols that can help reduce trans-epidermal water loss, thereby helping to keep skin moisturized. Phytosterols also help to repair skin damaged by environmental factors including sun damage. It’s a great source of alpha linolenic acid – an essential fatty acid that has regenerative and anti-aging skin benefits. Red raspberry seed oil also has a low comedogenic rating of 0-1, meaning it’s not likely to clog pores.   CRANBERRY SEED OIL Cranberry Seed Oil, cold pressed from the seed of the super fruit, is unique among the fixed oils because it contains a very high essential fatty acid profile, along with a good mixed tocopherols and tocotrienols (vitamin E) content, high phytosterols, and a 1:1 ratio of omega 3 to omega 6 essential fatty acids which gives it excellent anti-oxidant activity and skin nurturing benefits.   Cranberry Seed Oil contains one of the highest antioxidants and phytosterols content of any of the vegetable / fruit oils, making it an excellent addition to your natural sun protection products where it will help to prevent photo damage.   Anti-oxidants that are consumed can reach the skin but, with free radical damage being the heaviest assault on the skin, and the cause of almost all of the signs of aging and unhealthy skin, it is beneficial to apply them topically where their protection can go to work immediately.   Antioxidant Protection Skin Conditioning and Restructuring Vitamins A, C, E, and K Enhanced Cellular Function Aids in the Skin's Absorption, and Utilization, of Essential Fatty Acids Cranberry seed oil has the perfect ratio of omega-3 to omega-6 fatty acids, meaning it will absorb into your skin very well. Exceptional Skin Moisturizer Skin Tightening Activity Natural brightener. If your face is looking a little on the dull side, use this oil for a natural glow.   TREMELLA MUSHROOM Tremella fuciformis is one of the great superfood mushrooms and longevity tonic herbs in Traditional Chinese medicine (TCM). It’s use dates back as far as 200 A.D. when it was including in one of the earliest TCM classics- the materia medica by "Shen Nong Ben Cao Jing”, the father of Chinese medicine. In ancient times, like many of the other revered medicinal mushrooms such as Reishi and Cordyceps sinensis, Tremella was only reserved for royalty, ruling family members or for rich people who could afford this highly valued superfood.   For centuries, Chinese women have been consuming Tremella in its whole mushroom form and as a mushroom extract to make their skin more moist, soft and pliable. Its recognized as one of the best tonic herbs to help maintain the health of the skin as the body ages.   Tremella mushroom belongs to the jelly fungus family and has many different names. In Chinese, it's called silver ear mushroom (pinyin: yín ěr), white wood-ear mushroom (pinyin: yín ěr), and in Japanese, it's called shiro kikurage which translates to “white tree jellyfish”. It's also commonly known as “snow fungus” and the “beauty mushroom”.   Dermatologist Dendy Engelman, the director of dermatologic surgery at Metropolitan Hospital in New York City, says the fungus acts similar to that of hydration powerhouse hyaluronic acid by pulling moisture to the skin. Hyaluronic acid can hold up to 1,000 times its weight in water, so finding an all-natural match for its hydrating power is pretty major. And snow mushroom has an extra edge. "The particles are smaller than hyaluronic acid so it penetrates the skin more easily," says Engelman.   Tremella mushroom has many restorative benefits but it's most famous for its beauty and skin enhancing properties:   Nourishes Skin Naturally Moisturizes When applied topically, Tremella generates a natural hydration film on the skin that can help relieve dryness, support overall skin health by balancing optimal hydration and enabling the skin to develop elasticity and appear more supple and full.  Improves Elasticity Tremella’s ability to absorb into the deeper layers of the skin works to enhance skin elasticity and helps plump & smooth out fine lines and wrinkles. Even better, Tremella also has an incredible ability to break down free radicals - which prevents fine lines and wrinkles from forming in the first place!  Slows Skin Aging Brightens Complexion Deeply Hydrates Inside and Out Boasts High Concentration of Vitamin D This mushroom also happens to be high in Vitamin D. When eaten, Tremella mushroom is the highest food source of the Vitamin D precursor, pro-vitamin D. When topically applied, Vitamin D has also shown impressive skin healing abilities. It helps cell growth, wound healing, and maintaining the barrier function of the skin. Basically, it’s like nature’s Band-Aid.  And now for a less-fun fact?Between the ages of 20-70, the skin’s natural ability to create Vitamin D decreases by 75%. This is why it's essential to support your skin with extra, high quality sources of Vitamin D such as Tremella.  The nutritional profile for Tremella includes: ∙ Protein and amino acids ∙ Enzymes ∙ Vitamins ∙ Minerals ∙ Polysaccharides ∙ Beta-Glucans ∙ Flavonoids ∙ Carotenoids ∙ Beta-Glucans ∙ Phenols and polyphenols ∙ Alkaloids ∙ Organic acids In addition to being a potent immune stimulant, one of nature’s richest sources of vitamin D and containing high levels of antioxidants, Tremella is brimming with medicinal properties, as you can see!   Celery Seed Extract The essential oil of celery seed is derived from the celery plant, scientifically known as Apium graveolens from the Umbelliferae plant family. Celery is not just a vegetable used for salads and stir-fries, but it is a revered herb to the Chinese as early as in the 5th century and is even widely used in the Indian Ayurvedic medicinal area.   Not only that, celery was held in high and sacred regard during the Greek era. In fact, it was believed that celery was used in the tomb of the famous Pharaoh Tutankhamun and mentioned in the works of the great and famous Roman encyclopaedist, Aulus Cornelius Celsus!   All these examples mentioned attest to the high medicinal value of celery and the essential oil derived from its plant, so let’s find out more about what celery seed essential oil can do to benefit our SKIN! Containing vitamins A, C, and K, celery extract is an antioxidant-rich ingredient that can help repel free radicals, ward off photoaging, and ensure continual cell turnover. Antioxidants are true powerhouses, both in skincare and in our diets – so suffice to say, we’re thrilled to introduce this potent ingredient in REVERSE!     Linseed Extract You've probably already heard of linseed oil which is often used in manufacturing paints and varnishes as well as inks for printing purposes. These days, it's being utilized in a lot of various products.   Did you know that the linseed extract which is expressed from the oil-rich seeds of the flax flower is also highly employed in the production of cosmetics and skincare items? This is because it's also been proven valuable for enhancing the skin's appearance and health.   Protects the cells from oxidative damage and ensures optimal mitochondrial activity. Linseed extract is extremely high in omega-3 fatty acids, B vitamins, potassium, lecithin, magnesium, fiber, protein and zinc, which gives it strong anti-aging capabilities to reduce wrinkles and increase firmness. Three of the skin-altering conditions you can avoid if protected with linseed extract topically include; Inflammation, Aging, and Allergies     ROSE GERANIUM ESSENTIAL OIL A rose geranium is a type of geranium plant with leaves that smell strongly like roses. This species of geranium is native to certain parts of Africa.   It’s also called rose-scented geranium, sweet-scented geranium, or old-fashioned rose geranium. The plant has velvety, plush leaves and flowers that bloom pale pink or almost white.   A 2017 review of studies demonstrated that antioxidant properties in rose geranium oil may help reduce the signs of aging. The anti-inflammatory properties of rose geranium oil have been demonstrated in animal studies. In fact, one 2013 study showed rose geranium oil had a strong impact on reducing swelling in mice paws and ears. It suggested that rose geranium oil could be the basis of new anti-inflammatory drugs that may have less harmful side effects than current medications. Rose geranium oil has strong antimicrobial, antifungal, and antiviral properties. The food service industry even uses rose geranium oil as a natural preservative in some food products. In one 2017 review of studies, rose geranium was shown to reduce bacterial, fungi, and viruses that cause skin disease and infections.     RESOURCES   NEW! Organixx Skin’s – REVERSE Anti-Aging Serum https://shop.organixx.com/products/reverse-antiaging-serum?gl=5f19d0428ebf584f6d7b23c6   Organixx Skin’s – RESTORE Vitamin C Serum https://shop.organixx.com/products/restore-vitamin-c-serum?gl=5f19cf988ebf58b96e7b23c6   Organixx Skin’s – RENEW Eye Crème https://shop.organixx.com/products/renew-eye-cream?gl=5f19cf5e8ebf58f1677b23c7   Face Serum: Why You Should Use One https://www.paulaschoice.com/expert-advice/skincare-advice/anti-aging-wrinkles/why-you-should-consider-using-a-serum.html   Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics https://www.sciencedirect.com/science/article/pii/S0047637418300435   Body image, aging, and identity in women over 50: The Gender and Body Image (GABI) study https://www.tandfonline.com/doi/abs/10.1080/08952841.2015.1065140   Wikipedia https://en.wikipedia.org/wiki/Dermal_fibroblast   Human Dermal Fibroblasts (HDF) https://www.cellapplications.com/human-dermal-fibroblasts-hdf   The hallmarks of fibroblast aging. https://www.ncbi.nlm.nih.gov/pubmed/24686308   The effect of aging in primary human dermal fibroblasts https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219165   Skin ages when the main cells in the dermis lose their identity and function https://www.sciencedaily.com/releases/2018/11/181108134147.htm   Understanding Dermal Stem Cells  https://pdfs.semanticscholar.org/05d2/9b270ff706b3421eb5eaa12f154d0d882635.pdf   Activation of Mesenchymal Progenitor Cells to Correct Signs of Skin Aging http://tst.pg2.at/abstracts/data/full_papers/full_paper_19.pdf   School of Natural Skincare International https://www.schoolofnaturalskincare.com/6-reasons-to-use-raspberry-seed-oil-in-your-natural-skincare-products/   Characteristics of raspberry (Rubus idaeus L.) seed oil https://www.sciencedirect.com/science/article/pii/S0308814699002605   Cranberry Seed Oil – Unrefined http://www.ingredientstodiefor.com/item/Cranberry_Seed_Oil_Unrefined/1164   INGREDIENT SPOTLIGHT ON CRANBERRY SEED OIL https://jordansamuelskin.com/blogs/news/ingredient-spotlight-on-cranberry-seed-oil   Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils https://www.sciencedirect.com/science/article/pii/S0308814604005412   Cranberry seed oil extract and compositions containing components thereof – Patent https://patents.google.com/patent/US6641847B1/en   Ancient Beauty Secrets of Tremella Mushroom (For Flawless Skin) https://teelixir.com/blogs/news/ancient-beauty-secrets-tremella-mushroom   Medicinal Value of the Genus Tremella Pers. (Heterobasidiomycetes) (Review) http://www.dl.begellhouse.com/journals/708ae68d64b17c52,580b7b864183d53b,567a96af6caf987e.html   Mushroom Cosmetics: The Present and Future https://www.mdpi.com/2079-9284/3/3/22   Skin Wound Healing Promoting Effect of Polysaccharides Extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo Porcine Skin Wound Healing Model https://pdfs.semanticscholar.org/a84a/e79d2e3124440e80a7070c7770475485cb06.pdf   Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging https://www.sciencedirect.com/science/article/abs/pii/S175646461500554X   Pelargonium graveolens (Rose Geranium) – A Novel Therapeutic Agent for Antibacterial, Antioxidant, Antifungal and Diabetics https://www.acanceresearch.com/cancer-research/pelargonium-graveolens-rose-geranium--a-novel-therapeutic-agent-for-antibacterial-antioxidant-antifungal-and-diabetics.php?aid=18420   Rose geranium essential oil as a source of new and safe anti-inflammatory drugs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793238/   Rose Geranium Essential Oil as a Source of New and Safe Anti-Inflammatory Drugs https://pubmed.ncbi.nlm.nih.gov/24103319/   Subscribe to Empowering You Organically 
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MedMechanix
MM8: OTC Med Guide

MedMechanix

Play Episode Listen Later Jul 31, 2020 52:10


Join us for a basic guide to over the counter medications for providers. We will cover cough, runny nose, allergies, acid reflux, pain, antifungals. We also go over guidelines on how to choose the right combination cold and flu medications.  Today's PDF Handout: https://www.medmechanix.com/wp-content/uploads/2020/07/otc.pdf Our website: https://www.medmechanix.com Dextromethorphan study link: https://jamanetwork.com/journals/jamapediatrics/fullarticle/571638 Steroid Potency Article: https://www.verywellhealth.com/steroids-topical-steroid-strengths-1068832

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School
Simple Nursing Pharmacology Antifungal NCLEX Questions

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School

Play Episode Listen Later Jun 15, 2020 3:04


Free quiz & full course at https://Simplenursing.com/nursing-school  Pharmacology Master Class - 100 videos not on YouTube - Try it for Free!    Pharmacology Master Class - Try it for Free: https://Simplenursing.com/nursing-school  100 videos not on YouTube    FREE Access to new app + 1,000 videos not on youtube!  https://Simplenursing.com/nursing-school   NCLEX FREE TRIAL:  https://simplenursing.com/NCLEX   STAY IN TOUCH

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School
Simple Nursing Pharmacology Antifungal Nystatin

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School

Play Episode Listen Later Jun 15, 2020 3:02


Free quiz & full course at https://Simplenursing.com/nursing-school  Pharmacology Master Class - 100 videos not on YouTube - Try it for Free!    Pharmacology Master Class - Try it for Free: https://Simplenursing.com/nursing-school  100 videos not on YouTube    FREE Access to new app + 1,000 videos not on youtube!  https://Simplenursing.com/nursing-school   NCLEX FREE TRIAL:  https://simplenursing.com/NCLEX   STAY IN TOUCH

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School
Simple Nursing Pharmacology Antifungal AmphotericinB

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School

Play Episode Listen Later Jun 15, 2020 0:30


Free quiz & full course at https://Simplenursing.com/nursing-school  Pharmacology Master Class - 100 videos not on YouTube - Try it for Free!    Pharmacology Master Class - Try it for Free: https://Simplenursing.com/nursing-school  100 videos not on YouTube    FREE Access to new app + 1,000 videos not on youtube!  https://Simplenursing.com/nursing-school   NCLEX FREE TRIAL:  https://simplenursing.com/NCLEX   STAY IN TOUCH

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School
Simple Nursing Pharmacology Antifungal Fluconazole

The Simple Nursing Podcast - The Simplest Way To Pass Nursing School

Play Episode Listen Later Jun 15, 2020 0:52


Free quiz & full course at https://Simplenursing.com/nursing-school  Pharmacology Master Class - 100 videos not on YouTube - Try it for Free!    Pharmacology Master Class - Try it for Free: https://Simplenursing.com/nursing-school  100 videos not on YouTube    FREE Access to new app + 1,000 videos not on youtube!  https://Simplenursing.com/nursing-school   NCLEX FREE TRIAL:  https://simplenursing.com/NCLEX   STAY IN TOUCH

Empowered Patient Podcast
Antifungal and Antiviral Conjugates Platforms Fighting Infectious Diseases with Jeff Stein Cidara Therapeutics TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later May 26, 2020


Jeff Stein, President and CEO, Cidara Therapeutics talks about  their antifungal platform rezafungin now in Phase 3 clinical development to address the needs of the vulnerable population of patients hospitalized for something else who get a life-threatening fungal infection in the hospital. Jeff also explains their Cloudbreak Antiviral Conjugates platform that is being used to target influenza and COVID-19.  Cidara is not developing vaccines or monoclonal antibodies rather long-acting drugs that are virucidal and that recruit the immune system to clean up the infection. He also clearly describes the differences between fungi and viruses. @CidaraThera @JeffStein #coronavirus #COVID19 #influenza #fungalinfections #antifungal #antiviral Cidara.com Listen to the podcast here

Empowered Patient Podcast
Antifungal and Antiviral Conjugates Platforms Fighting Infectious Diseases with Jeff Stein Cidara Therapeutics

Empowered Patient Podcast

Play Episode Listen Later May 26, 2020 17:27


Jeff Stein, President and CEO, Cidara Therapeutics talks about  their antifungal platform rezafungin now in Phase 3 clinical development to address the needs of the vulnerable population of patients hospitalized for something else who get a life-threatening fungal infection in the hospital. Jeff also explains their Cloudbreak Antiviral Conjugates platform that is being used to target influenza and COVID-19.  Cidara is not developing vaccines or monoclonal antibodies rather long-acting drugs that are virucidal and that recruit the immune system to clean up the infection. He also clearly describes the differences between fungi and viruses. @CidaraThera @JeffStein #coronavirus #COVID19 #influenza #fungalinfections #antifungal #antiviral Cidara.com Download the transcript

Dermatology Weekly
Treatment adherence to topicals for psoriasis, plus coronavirus prompts cancellation of AAD

Dermatology Weekly

Play Episode Listen Later Mar 12, 2020 17:58


Consider poor adherence rather than recalcitrant disease in psoriasis patients who do not respond to topical treatment. Dr. Vincent DeLeo talks with Dr. Nwanneka Okwundu and Dr. Steven Feldman about strategies to promote better treatment adherence. They discuss factors that contribute to poor adherence and offer tips to motivate patients to stick to their treatment regimens. “There’s a lot we can do to get people to use their medicine better.  ... Our job is to get people well. And to do that, we have to make the right diagnosis, prescribe the right therapy, and do those things that need to be done to get patients to put the medicine on,” explains Dr. Feldman. * * *   We also bring you the latest in dermatology news and research: 1. Coronavirus outbreak prompts cancellation of AAD annual meetingThe American Academy of Dermatology annual meeting is the latest large medical conference to be canceled because of the coronavirus disease 2019 (COVID-19) outbreak. 2. Antifungal drug terbinafine appears safe for pregnancyTreatment with terbinafine during pregnancy does not appear to increase the risk of major malformations or spontaneous abortions. 3. Toys may be the culprit for children with contact allergiesA variety of toys such as video game controllers, tablets, dolls, bikes, and toy cars, can cause contact dermatitis in children because of the nature of their respective ingredients. *  *  *   Things you will learn in this episode: A recent study evaluated whether psoriasis patients who were resistant to topical corticosteroids responded under conditions designed to promote treatment adherence, which included telephone reminders, frequent study visits, and use of a spray vehicle vs. an ointment. Most participants improved in all measurement parameters, but the randomized group of patients who received telephone calls showed more improvement in disease severity than those who did not receive telephone calls. “This idea that topical therapy doesn’t work, I think, is based on a misconception. It’s based on our observations that it doesn’t work, but we’re not seeing how poorly compliant patients are. If we take people who fail topical therapy and do things to really get them to use their topical medication well, their skin disease clears up,” Dr. Feldman explains. In addition to making the diagnosis and prescribing treatment, dermatologists play an important role in getting psoriasis patients to use their medications: “If you tell people, ‘Here, put this topical therapy on. It’s messy, I’ll see you in 3 months,’ you’ll be like a piano teacher saying, ‘Here’s a really complicated piece of music, practice it every day, I’ll see you at the recital in 3 months.’ It’s just not going to sound like a very good recital,” Dr. Feldman notes. Practical alternatives to frequent office visits that dermatologists can use to answer patient questions and promote treatment adherence include virtual visits (teledermatology) and electronic interactions (telephone calls, email correspondence). It is important to prescribe therapies that are consistent with a patient’s preferred vehicle. “If the patient prefers a spray, give them a spray. If they want an ointment, give them an ointment. They are more likely to use it that way,” Dr. Okwundu recommends. When starting patients on a new treatment, hold them accountable by having them check in with you to let you know how they are doing. “Maybe we don’t need to see people every 3 days, but we need to make sure patients realize we care about them, because they don’t want to let us down if we have the kind of strong human relationship with them and then we have to hold them accountable,” Dr. Feldman advises. *  *  *   Hosts: Nick Andrews; Vincent A. DeLeo, MD (University of Southern California, Los Angeles) Guests: Nwanneka Okwundu, DO; Steven R. Feldman, MD, PhD (both are with Wake Forest University, Winston-Salem, N.C.). Show notes by: Alicia Sonners, Melissa Sears, Elizabeth Mechcatie *  *  *   You can find more of our podcasts at http://www.mdedge.com/podcasts      Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgeDerm

Outbreak News Interviews
Aspergillosis, a new kind of antifungal drug and World Aspergillosis Day

Outbreak News Interviews

Play Episode Listen Later Feb 28, 2020 12:35


Today is World Aspergillosis Day, a day to raise awareness about a fungal infection that kills more than one million people globally each year. Joining me now to talk about aspergillosis, a new kind of antifungal drug and World Aspergillosis Day is Marco Taglietti, M.D. Dr Taglietti is the president and chief executive officer of SCYNEXIS and an infectious disease expert.

Outbreak News Interviews
Aspergillosis, a new kind of antifungal drug and World Aspergillosis Day

Outbreak News Interviews

Play Episode Listen Later Feb 27, 2020 12:35


Today is World Aspergillosis Day, a day to raise awareness about a fungal infection that kills more than one million people globally each year. Joining me now to talk about aspergillosis, a new kind of antifungal drug and World Aspergillosis Day is Marco Taglietti, M.D. Dr Taglietti is the president and chief executive officer of […] The post Aspergillosis, a new kind of antifungal drug and World Aspergillosis Day appeared first on Outbreak News Today.

LaserNailTherapyClinic
Toenail Fungus in Athletes

LaserNailTherapyClinic

Play Episode Listen Later Feb 1, 2020 1:51


Laser Nail Therapy - Cure Your Nail Fungus Today! http://www.lasernailtherapy.com (800) 672-0625 Fungal toenails is one of the most common issues why people visit a podiatrist. Fungi can infect the nail after an injury or trauma from playing sports such as football or basketball. As an athlete, you can be highly susceptible to a fungal infection. Another reason to get a fungal infection is the environment your toenails are in. The shoes you wear is the perfect environment for fungus to thrive. It is usually moist and warm due to sweat. The problem is, if you get fungus in your toenails, it can be very difficult to get rid of. It is almost impossible to treat it without professional help. If you ignore the problem, it will just get worse and more difficult to treat. And because the infection starts small, you might not notice it right away until it is too late. Common treatment options that are readily available are topical treatments such as antifungal creams or solutions. These topical treatments may seem easy but it is not very effective. Another option is oral medication. This type of treatment is more effective than topicals, but it has harmful side effects. Antifungal pills can cause liver damage, stomach issues, and skin rashes. The most effective way to eradicate a fungal infection of the toenails is with laser treatment. In our clinics, we use the FDA approve PinPointe Laser. This is the most effective laser in the market, and does not harm the nail or the surrounding skin nor cause any dangerous side effects.. If you have nail fungus or it’s symptoms, give us a call at (800)672-0625 to schedule a Free Consultation with our doctors or visit our website at http://www.lasernailtherapy.com

Radio Naturopath
Radio Naturopath Episode 241: Neem the Antifungal, Body Lotion, Microbiome Food Test, Genetic Testing

Radio Naturopath

Play Episode Listen Later Jan 20, 2020 57:40


All about NEEM, an ayurvedic herb that cured my athlete’s foot, I’m so excited! Plus other things Neem helps, like hair, skin and nails, and reducing inflammation and infections. Body lotion can be nice as long as it has natural ingredients. There’s this new test, Viome, where you send in a stool sample and it […]

CReATe Connect Podcast
ALS Untangled Series: Ep. 21 - Anti-fungals

CReATe Connect Podcast

Play Episode Listen Later Nov 13, 2019 9:21


One group has reported evidence of fungal infections in the brains of patients who died from ALS. Here we explore the potential explanations for this finding, and the potential for anti-fungal medications as an ALS treatment.

CReATe Connect Podcast
ALS Untangled Series: Ep. 21 - Anti-fungals

CReATe Connect Podcast

Play Episode Listen Later Nov 13, 2019 9:21


One group has reported evidence of fungal infections in the brains of patients who died from ALS. Here we explore the potential explanations for this finding, and the potential for anti-fungal medications as an ALS treatment.

The Cultivate Wellness Podcast
Ep 39 - Dr. Rob MacCuspie, Silver Nano Particles and Human Health

The Cultivate Wellness Podcast

Play Episode Listen Later Sep 11, 2019 47:34


Dr. Rob MacCuspie, Director of Science at Natural Immunogenics Corporation joins us to discuss silver and human health! Is silver antibacterial? Yes. Antiviral? Yes. Antifungal?! YES! web: cultivatewellnesspodcast.com social: @cultivatewellnesspodcast Always brought to you by Peoples Rx, Austin's Favorite Pharmacy!

Big JuJu Media (NEW)
SHOW #321 - Topless Tarot, Global INFECTION Alert, NEW Antifungal Soaps, And More!

Big JuJu Media (NEW)

Play Episode Listen Later Apr 9, 2019 30:24


SHOW #321 - Topless Tarot, Global INFECTION Alert, NEW Antifungal Soaps, And More to help you GET BETTER with your dreams, your manifestation techniques, so much more that I'm shocked at how much there is to give you over the psychic airwaves! --- Support this podcast: https://anchor.fm/bigjujumedia/support

Big JuJu Media (Original)
SHOW #321 - Topless Tarot, Global INFECTION Alert, NEW Antifungal Soaps, And More!

Big JuJu Media (Original)

Play Episode Listen Later Apr 8, 2019 30:25


SHOW #321 - Topless Tarot, Global INFECTION Alert, NEW Antifungal Soaps, And More to help you GET BETTER with your dreams, your manifestation techniques, so much more that I'm shocked at how much there is to give you over the psychic airwaves!

The Urban Farm Podcast with Greg Peterson
412: William Bruneau on The Genus Sida

The Urban Farm Podcast with Greg Peterson

Play Episode Listen Later Jan 1, 2019 41:13


Growing an herbal antibiotic. In This Podcast: Bill Bruneau suffered from what eventually was diagnosed as a leaky gut caused by using pharmaceutical antibiotics. Knowing that plants had medicinal powers he searched out which ones were natural antibiotics and came upon limited but intriguing information on the genus Sida. He waited for someone to write a book about this super-weed and when no one did, Bill knew he had to do it. Listen as Bill lists just a few of the many illnesses he uses Sida to treat or prevent.   Don't miss an episode! Click here to sign up for podcast updatesor visit www.urbanfarm.org/podcast In 1982, Bill and his wife started Bountiful Gardens Seeds, which is part of the small non-profit Ecology Action of the Mid-peninsula. Ecology Action is an organization that has been diligently working to save the world's soil for the last 45 years, refining and promoting a bio-intensive farming method that actually creates soil while being very productive.   While Bill is an herbal hobbyist, medicinal herbs and preventative medicine have been at the core of his family's health for at least 50 years and when he discovers one that is as good as Sida appeared to be, he wanted to know everything about it. A scientist at heart, he did intensive research into the known benefits of Sida for over a year, seeking out peer-reviewed research on Sida, and in particular studies on Sida acuta. The results have exceeded his wildest expectations.   Go to www.urbanfarm.org/sida for more information and links on this podcast, and to find our other great guests. 412: William Bruneau on the Genus Sida

Dr. Carolyn Dean Live
Dr. Carolyn Dean LIVE

Dr. Carolyn Dean Live

Play Episode Listen Later Oct 23, 2018


Have you or someone you love been advised to avoid iodine supplementation? Allopathetic doctors are most likely to make this recommendation followed by naturopathic doctors that don’t understand the role of iodine in the body. The typical mistake with iodine supplementation is the shallow understanding that its only role is as a substrate for the formation of thyroid hormone. Not so. Every cell in the body needs iodine: Iodine is required to prevent an attack from the sea of microbes they are surrounded by. Our bodies are saturated by 10 times more germs than human cells and iodine functions like chlorine in a pool keeping germs at bay. For example, white blood cells cannot effectively guard against infection without adequate amounts of iodine. Iodine is responsible for the formation of the normal architecture of the glandular tissue, e.g. breast, thyroid, ovary, & prostate, Iodine is utilized in the management of insulin and is effective in lowering blood sugar. Elevates pH (Iodine is an alkalinizing agent) Iodine is necessary for the production of all the hormones of the body (adrenals, ovaries, testicles, etc.)testicles Therefore, much more iodine is needed than just for thyroid hormone formation! Iodine has tremendous therapeutic actions at the cellular level – iodine can act as an alkalinizing agent, an Antibacterial, an Antiparasitic, an Antifungal an Antiviral and a Detoxifying agent If you have been advised to take iodine by a doctor or medical professional, then you’ll want to take iodine that is fully absorbed at the cellular level and in a balanced dose along with the other minerals it requires for beneficial interactions in the body. Tonight on our internet based radio show, we'll be talking with Dr. Carolyn Dean about Iodine - Proper Supplementation for Optimal Health along with a wide range of health topics and safe solutions. You will love hearing the beneficial interactions with our callers and hosts alike including the body/mind connection, identifying the 'conflict' in the 'conflict basis' of disease and much more!!

Dr. Carolyn Dean Live
Dr. Carolyn Dean LIVE

Dr. Carolyn Dean Live

Play Episode Listen Later Oct 23, 2018


Have you or someone you love been advised to avoid iodine supplementation? Allopathetic doctors are most likely to make this recommendation followed by naturopathic doctors that don’t understand the role of iodine in the body. The typical mistake with iodine supplementation is the shallow understanding that its only role is as a substrate for the formation of thyroid hormone. Not so. Every cell in the body needs iodine: Iodine is required to prevent an attack from the sea of microbes they are surrounded by. Our bodies are saturated by 10 times more germs than human cells and iodine functions like chlorine in a pool keeping germs at bay. For example, white blood cells cannot effectively guard against infection without adequate amounts of iodine. Iodine is responsible for the formation of the normal architecture of the glandular tissue, e.g. breast, thyroid, ovary, & prostate, Iodine is utilized in the management of insulin and is effective in lowering blood sugar. Elevates pH (Iodine is an alkalinizing agent) Iodine is necessary for the production of all the hormones of the body (adrenals, ovaries, testicles, etc.)testicles Therefore, much more iodine is needed than just for thyroid hormone formation! Iodine has tremendous therapeutic actions at the cellular level – iodine can act as an alkalinizing agent, an Antibacterial, an Antiparasitic, an Antifungal an Antiviral and a Detoxifying agent If you have been advised to take iodine by a doctor or medical professional, then you’ll want to take iodine that is fully absorbed at the cellular level and in a balanced dose along with the other minerals it requires for beneficial interactions in the body. Tonight on our internet based radio show, we'll be talking with Dr. Carolyn Dean about Iodine - Proper Supplementation for Optimal Health along with a wide range of health topics and safe solutions. You will love hearing the beneficial interactions with our callers and hosts alike including the body/mind connection, identifying the 'conflict' in the 'conflict basis' of disease and much more!!

Dr. Carolyn Dean Live
Dr. Carolyn Dean LIVE

Dr. Carolyn Dean Live

Play Episode Listen Later Oct 22, 2018


Have you or someone you love been advised to avoid iodine supplementation? Allopathetic doctors are most likely to make this recommendation followed by naturopathic doctors that don’t understand the role of iodine in the body. The typical mistake with iodine supplementation is the shallow understanding that its only role is as a substrate for the formation of thyroid hormone. Not so. Every cell in the body needs iodine: Iodine is required to prevent an attack from the sea of microbes they are surrounded by. Our bodies are saturated by 10 times more germs than human cells and iodine functions like chlorine in a pool keeping germs at bay. For example, white blood cells cannot effectively guard against infection without adequate amounts of iodine. Iodine is responsible for the formation of the normal architecture of the glandular tissue, e.g. breast, thyroid, ovary, & prostate, Iodine is utilized in the management of insulin and is effective in lowering blood sugar. Elevates pH (Iodine is an alkalinizing agent) Iodine is necessary for the production of all the hormones of the body (adrenals, ovaries, testicles, etc.)testicles Therefore, much more iodine is needed than just for thyroid hormone formation! Iodine has tremendous therapeutic actions at the cellular level – iodine can act as an alkalinizing agent, an Antibacterial, an Antiparasitic, an Antifungal an Antiviral and a Detoxifying agent If you have been advised to take iodine by a doctor or medical professional, then you’ll want to take iodine that is fully absorbed at the cellular level and in a balanced dose along with the other minerals it requires for beneficial interactions in the body. Tonight on our internet based radio show, we'll be talking with Dr. Carolyn Dean about Iodine - Proper Supplementation for Optimal Health along with a wide range of health topics and safe solutions. You will love hearing the beneficial interactions with our callers and hosts alike including the body/mind connection, identifying the 'conflict' in the 'conflict basis' of disease and much more!!

Dr. Carolyn Dean Live
Dr. Carolyn Dean LIVE

Dr. Carolyn Dean Live

Play Episode Listen Later Oct 22, 2018


Have you or someone you love been advised to avoid iodine supplementation? Allopathetic doctors are most likely to make this recommendation followed by naturopathic doctors that don’t understand the role of iodine in the body. The typical mistake with iodine supplementation is the shallow understanding that its only role is as a substrate for the formation of thyroid hormone. Not so. Every cell in the body needs iodine: Iodine is required to prevent an attack from the sea of microbes they are surrounded by. Our bodies are saturated by 10 times more germs than human cells and iodine functions like chlorine in a pool keeping germs at bay. For example, white blood cells cannot effectively guard against infection without adequate amounts of iodine. Iodine is responsible for the formation of the normal architecture of the glandular tissue, e.g. breast, thyroid, ovary, & prostate, Iodine is utilized in the management of insulin and is effective in lowering blood sugar. Elevates pH (Iodine is an alkalinizing agent) Iodine is necessary for the production of all the hormones of the body (adrenals, ovaries, testicles, etc.)testicles Therefore, much more iodine is needed than just for thyroid hormone formation! Iodine has tremendous therapeutic actions at the cellular level – iodine can act as an alkalinizing agent, an Antibacterial, an Antiparasitic, an Antifungal an Antiviral and a Detoxifying agent If you have been advised to take iodine by a doctor or medical professional, then you’ll want to take iodine that is fully absorbed at the cellular level and in a balanced dose along with the other minerals it requires for beneficial interactions in the body. Tonight on our internet based radio show, we'll be talking with Dr. Carolyn Dean about Iodine - Proper Supplementation for Optimal Health along with a wide range of health topics and safe solutions. You will love hearing the beneficial interactions with our callers and hosts alike including the body/mind connection, identifying the 'conflict' in the 'conflict basis' of disease and much more!!

SipNSci
Codeine Crazy: Natural Products and Antifungal Resistance

SipNSci

Play Episode Listen Later Aug 31, 2018 82:32


This episode I talk to Tanei The Science Guy about natural product synthesis, anti fungal resistance, and how all the Future grade drugs have a lot more in common than you think. Get more from Tanei at @TJRicks_TSP or at https://www.taneithescienceguy.com/subscribe.

Building Fortunes Radio with Host Peter Mingils
Pure Light Bulbs Antifungal Anti bacterial Peter Mingils Roger K Young

Building Fortunes Radio with Host Peter Mingils

Play Episode Listen Later Sep 6, 2017 31:00


Pure Light Bulbs Antifungal Anti bacterial Peter Mingils Roger K Young

Revive Yourself Podcast With Ryan Martin
026 – Revive Yourself – Daniel & Lindsay Crouch From Guiltless Superfoods On Why They Started The Guiltless Brand, Their 7 Seed Flour, Antifungal Foods & Much More

Revive Yourself Podcast With Ryan Martin

Play Episode Listen Later Aug 28, 2017 67:24


On today’s show I have Daniel and Lindsay Crouch from Guiltless Superfoods. I first came across Daniel & Lindsay whilst researching Doug Kaufmann’s antifungal diet. Some of the recipes Doug recommended contained Guiltless Superfoods tortillas, and seeing as tortillas are conventionally made with wheat and yeast, (both of which are not allowed on an antifungal diet) I took a closer look at the ingredients. What I found when researching into the ingredients was Daniel & Lindsay had replaced the wheat & yeast with their very own 7 seed flour blend. As soon as I saw this I knew I had to take a deeper look into their brand and some of the other foods they were making. What I found was exciting to say the least. There were doughnuts, cookies and muffins all made with this 7 seed flour and with none of the health destroying ingredients we are used to seeing in these delicious foods. One look at the reviews also told you just how tasty these foods were. I knew right then and there I had to get these guys on the show and get behind what they are doing. On the show we discussed: Daniel’s health journey and what made him and Lindsay start Guiltless Foods Lindsay’s background as a chef and her challenges making the 7 seed blend What is in the 7 seed blend and what makes the flour so powerful The powers of an antifungal diet How the Guiltless Foods have improved their own health Whether their kids enjoyed the foods The quality of their ingredients and the challenges they faced bringing the products to market What new products they have on the horizon & much more This really was a fun interview and the energy both Daniel & Lindsay brought to the episode was contagious and a testament to their personal health. What they are doing is game changing, and I definitely want to make their products available to people in the UK in the future. You can find Daniel & Lindsay here: www.guiltlesssuperfoods.com Enjoy the show and don’t forget to share it with your friends and family, as well as writing a comment, or a review on itunes. To Your Health & Happiness Ryan

Dermcast.tv Dermatology Podcasts
Newest Antifungal Agents

Dermcast.tv Dermatology Podcasts

Play Episode Listen Later Feb 8, 2017


From the SDPA Annual Summer Dermatology Conference 2016, held June 1 – 5 in Austin, Texas. Topic: Newest Antifungal Agents Faculty: Ted Rosen, MD Learning Objectives: 1.) To understand the mycological epidemiology of common fungal infections of the skin 2.) To have enhanced understanding of the particular shortcomings of antifungal [...]

FDA Drug Safety Podcasts
FDA Drug Safety Podcast: FDA cautions about dosing errors when switching between different oral formulations of antifungal Noxafil (posaconazole); label changes approved

FDA Drug Safety Podcasts

Play Episode Listen Later Jan 12, 2016 3:00


FDA Drug Safety Podcast: FDA cautions about dosing errors when switching between different oral formulations of antifungal Noxafil (posaconazole); label changes approved

Know The Cause Podcast
Osteoporosis - Episode 7

Know The Cause Podcast

Play Episode Listen Later Dec 16, 2015 14:53


Statin drugs, before they were used to lower your cholesterol levels, were used to kill fungus! Even more interesting is the fact that some research shows that lowering cholesterol isn’t the only thing that statin drugs can do-they might also grow bone. But I caution you that taking statin drugs is not, in my humbled opinion, the safest way to go, if you have bone loss. Statins have become the darlings of Wall Street, but be careful because the last darling of Wall Street may have injured more women than they helped; hormone replacement therapy, or HRT. The point of this podcast is to familiarize you with the bone loss-fungus link. Antifungal supplements and lifestyle changes may be in order, including diet and exercise, when brittle bones or bone loss is diagnosed.

LaserNailTherapyClinic
Nail Polish Can Cure Your Nail Fungus

LaserNailTherapyClinic

Play Episode Listen Later Jul 31, 2015 1:15


Have you ever thought about covering up your unsightly fungal nails without infecting or reinfecting yourself? Perhaps you have thought about doing so with nail polish, but still want your nails to breathe. Well the solution is here and i know just the one. Scientists and polishing companies have developed nail polishes with antifungal remedies in them. This means that nail fungus sufferers can now cover up those embarrassing discolored and bruised up nails without feeling like they are causing more harm than good. There are several brand options out there and many of them have different remedy properties. Some include tea tree oil, others contain something with a little more powerful antifungal agents such as acetate. Both of these are safe options and have no harmful side effects. You may find these antifungal nail polishes online or in some clinics, such as our own, Laser Nail Therapy Clinic. We also offer the polishes on our website under “shop” tab or you may purchase them in any one of our offices. Antifungal nail polishes are a great way in not only covering up your embarrassing nail fungus, but also serve to help treat your nails in the process. For more information, please contact our office at 3939 J St. Suite 270 Sacramento, CA 95819 (800) 672-0625

Smart Digestion Radio
SDR 15: The 15 Powerful Benefits of Cinnamon

Smart Digestion Radio

Play Episode Listen Later Feb 26, 2014 24:59


Did you know that countries throughout history battled over cinnamon? Or that the spice was once used as a form of currency? After listening to this episode, I’m sure you’ll see why. That’s because today, I’m going to share with you all the amazing health benefits of cinnamon. This spice has been used for more than 2,000 years for just about everything, from healing colds and coughs to boosting mood and memory. Listen in to hear how cinnamon can be used to help with blood sugar, circulation, and so much more. You can find show notes and more information by clicking here: http://thedigestiondoctor.com/15

Real Health - No Seriously!
Episode 7 - Raw Apple Cider Vinegar

Real Health - No Seriously!

Play Episode Listen Later Mar 12, 2012 24:03


Why is Raw Apple Cider Vinegar so great? Find out why. Learn about its many uses and how it can help you attain great health.

Medizin - Open Access LMU - Teil 17/22
Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

Medizin - Open Access LMU - Teil 17/22

Play Episode Listen Later Jan 1, 2011


The use of antimycotic drugs in fungal infections is based on the concept that they suppress fungal growth by a direct killing effect. However, amphotericin and nystatin have been reported to also trigger interleukin-1β (IL-1β) secretion in monocytes but the molecular mechanism is unknown. Here we report that only the polyene macrolides amphotericin B, nystatin, and natamycin but none of the tested azole antimycotic drugs induce significant IL-1β secretion in-vitro in dendritic cells isolated from C57BL/6 mouse bone marrow. IL-1β release depended on Toll-like receptor-mediated induction of pro-IL-1β as well as the NLRP3 inflammasome, its adaptor ASC, and caspase-1 for enzymatic cleavage of pro-IL-1β into its mature form. All three drugs induced potassium efflux from the cells as a known mechanism for NLRP3 activation but the P2X7 receptor was not required for this process. Natamycin-induced IL-1β secretion also involved phagocytosis, as cathepsin activation as described for crystal-induced IL-1β release. Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1β secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1. We conclude that beyond their effects on fungal growth, these antifungal drugs directly activate the host's innate immunity.

Focus on Allergy
Antifungal Treatment for Asthma

Focus on Allergy

Play Episode Listen Later May 1, 2009


Guest: John Heffner, MD Host: Maurice Pickard, MD Do allergies to various types of fungi trigger worsening of asthma? Are patients with severe asthma sensitive to certain species of fungus more than others? Dr. John Heffner, professor of medicine at the Oregon Health and Science University, discusses how patients with asthma might benefit from antifungal agents. Does off-label use of itraconazole for patients with severe asthma require long-term adherence for optimal asthma control? Dr. Maurice Pickard hosts.

Focus on Allergy
Antifungal Treatment for Asthma

Focus on Allergy

Play Episode Listen Later May 1, 2009


Guest: John Heffner, MD Host: Maurice Pickard, MD Do allergies to various types of fungi trigger worsening of asthma? Are patients with severe asthma sensitive to certain species of fungus more than others? Dr. John Heffner, professor of medicine at the Oregon Health and Science University, discusses how patients with asthma might benefit from antifungal agents. Does off-label use of itraconazole for patients with severe asthma require long-term adherence for optimal asthma control? Dr. Maurice Pickard hosts.