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This important Dementia 101 episode breaks down some of the “basics” of dementia, and guides us through the touching experiences of someone supporting a loved one. Guest Alexandra Aguzzi, who cares for her mom Anna, shares candid insights into her life as the caregiver of someone living with dementia, and reflects on moments along her and her mom's journey. Then neuroscientist, clinical neurologist and associate Professor in the Division of Neurology at the University of Alberta, Dr. Valerie Sim, helps us make sense of several major dementia diseases, including those affecting lex's mother. Visit us at defydementia.org. Our Guests: Alexandra Aguzzi, a retired civil servant, is the main caregiver to her mom, Anna Aguzzi. Early in life, Anna picked up a paintbrush and transformed a hobby into a life's passion, becoming a successful painter. Alexandra and Anna now enjoy spending time together at Baycrest, where Anna has been a resident for six years, following a diagnosis of Alzheimer's with Lewy body dementia. Dr. Valerie Sim is a neuroscientist, clinical neurologist, and Associate Professor in the Division of Neurology at the University of Alberta, as well as a scientist at the University's Centre for Prions and Protein Folding Diseases. Her research has explored dementia at many levels: from the misfolding of proteins in a tube, to growing slices of brain in a dish, to human diagnosis and treatment trials. She cares for people living with a variety of neurological disorders, including dementia, and teaches medical students and residents how to diagnose and help people living with complex neurological problems.
The tripods were out, legends were taking stats as Fantasy coaches dive into the unofficial practice matches to see which players they would like to select in their starting squads. Although we say every year that we need to be cautious with what data we extract from these games, it was good to just have footy back!In this episode, the panel does stocks up and stocks down with every match that was played last week. Which players have increased their value and which ones have dropped off? Find out what the boys think and more!The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Market Share Podcasts with Selby and Xavier Ellis Holmes Files episodes exclusive to the guide Much much more!The guide is now live! A must have for any serious Fantasy coach head over to moreirasmagic.com.au/ to order now! The guide will be updated right up until the start of round 1 and the in-season content beginsPODPOD ChallengeLeague code: JXR8EF6MAsk me on Qu Podpodafl has once again partnered with Qu platforms in 2026 to help answer your afl fantasy questions During the season - Selby and Holmesy will be recording a podcast late in the week to answer general questions and themes For a guaranteed answer and to help support the PODPOD, for a small fee you have the ability to have a personalised audio response to your afl fantasy questions There is the ability for full team reviews, questions on individual players and during the season there is the ability to ask trade questions, vc/c options and many more Head to https://askmeonqu.com/podpodafl now!Follow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesysheroesLewy: @AFLewyHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsenaDossy: @HKdos
In this episode, Trissell Hutchinson discusses exercise cueing strategies tailored to different subtypes of dementia. The conversation covers the four most common subtypes: Alzheimer's disease, vascular dementia, Lewy body dementia, and frontotemporal dementia. Each subtype is explored in terms of its characteristics, symptoms, and specific cues that can enhance patient care and therapy outcomes. The importance of understanding these differences is emphasized to provide effective support for individuals with dementia. 00:00Understanding Dementia: An Overview 02:23Alzheimer's Disease: Key Characteristics and Cues 04:46Vascular Dementia: Variability in Symptoms and Cues 06:11Lewy Body Dementia: Processing and Emotional Support 11:49Frontotemporal Dementia: Behavior and Language Variants Original published on PTonICE Jan 21 2026
Matt delves into the world of REM Sleep Behavior Disorder (RBD), a condition at the frontiers of sleep science. Normally, the brain dreams while atonia paralyzes the body in a neural magic act that is managed by brainstem nuclei activating inhibitory "brakes" in the spinal cord. When this circuit fails, the motor system remains active, enacting nightmares in real-time.RBD is hazardous - 10% of patients sustain injuries requiring medical intervention or hospitalization. It is a prodromal synucleinopathy where misfolded proteins erode the brain's architecture and 50% of patients develop Parkinson's or Lewy body dementia within a decade. Matt concludes by noting that new skin biopsy biomarkers like Syn-One now offer hope for early detection.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.One of today's sponsors, LMNT, offers a science-based electrolyte drink with no sugar or artificial ingredients. Try their new limited-time Lemonade Salt flavor! Get eight free sample packs with any order at drinklmnt.com/mattwalker. Stock up on this summer flavor while it lasts!In a supplement industry where trust is critical, Matt uses podcast supporter Puori. Their protein powders are free from hormones, GMOs, and pesticides, with every single batch third-party tested for over 200 contaminants. For protein you can trust, save 20% at puori.com/mattwalker.As always, if you have thoughts or feedback you'd like to share, please reach out:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube https://www.youtube.com/@sleepdiplomat
Live footy is back, unofficial practice matches are here and Opening Round is just around the corner! For months we have been researching players, looking at structures and building our AFL Fantasy squads. Today we get a look behind the curtains and get an official team reveal from Lewy who consistently finds himself at the top of the rankings!In this episode, the panel starts with all of the hot topics that have emerged since the last podcast recording. They then go through line by line for Lewy's team reveal, with Lewy giving in-depth knowledge on every player he has selected whilst Holmesy and Harmey quiz him on players who have missed out and the key structural questions. Lastly, the listener questions are back in 2026 so the boys dust them off and answer a bunch that weren't answered throughout the podcast!The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Market Share Podcasts with Selby and Xavier Ellis Holmes Files episodes exclusive to the guide Much much more!The guide is now live! A must have for any serious Fantasy coach head over to moreirasmagic.com.au/ to order now! The guide will be updated right up until the start of round 1 and the in-season content beginsPODPOD ChallengeLeague code: JXR8EF6MAsk me on Qu Podpodafl has once again partnered with Qu platforms in 2026 to help answer your afl fantasy questions During the season - Selby and Holmesy will be recording a podcast late in the week to answer general questions and themes For a guaranteed answer and to help support the PODPOD, for a small fee you have the ability to have a personalised audio response to your afl fantasy questions There is the ability for full team reviews, questions on individual players and during the season there is the ability to ask trade questions, vc/c options and many more Head to https://askmeonqu.com/podpodafl now!Follow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesysheroesLewy: @AFLewyHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsenaDossy: @HKdos
Dr. Greg Cooper and Dr. David G. Coughlin discuss the role of αSyn-SAAs in diagnosing DBL and their relationship with Alzheimer's disease biomarkers. Show citation: Coughlin DG, Jain L, Khrestian M, et al. CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression. Neurology. 2025;105(12):e214346. doi:10.1212/WNL.0000000000214346 Show transcript: Dr. Greg Cooper: Hi, this is Dr. Greg Cooper. I just finished interviewing Dr. David Coughlin for this week's Neurology Podcast. For today's Neurology Minute, I'm hoping you can tell us the main points of your paper. Dr. David Coughlin: The main points of this paper in my mind is that α-Synuclein seed amplification assays from cerebrospinal fluid samples is useful in confirming the presence of synuclein pathology in people with clinically suspected dementia with Lewy bodies. But also that, for people who have synuclein positivity, that the presence of Alzheimer's disease mixed pathology is associated with a worse cognitive progression over time. Dr. Greg Cooper: Thank you Dr. Coughlin, for that summary and for all of your work on this topic. Please check out this week's podcast to hear the full interview and read the full article published in Neurology, CSF α-Synuclein Seed Amplification Assays and Alzheimer's Disease Biomarkers in Dementia with Lewy Bodies. Thank you.
Dr. Greg Cooper talks with Dr. David G. Coughlin about the role of αSyn-SAAs in diagnosing dementia with Lewy bodies and their relationship with Alzheimer disease biomarkers. Read the related article in Neurology®. Disclosures can be found at Neurology.org.
Many patients will affirm seeing clouds shaped like animals or other similar phenomena, which is why confirming pareidolia (seeing meaningful images in meaningless visual stimuli) is such a tricky symptom in dementia with Lewy bodies (DLB). While it may not be exclusive to DLB, placing such symptoms in the context of "the company it keeps" is a key method to narrowing down the diagnosis. The Editors' Choice paper for the February 2026 issue of Practical Neurology is a practical guide to the clinical diagnosis and management of DLB. Authors Dr. Sarah Fullam¹ ² and Dr. Seán O'Dowd¹ ³ join PN podcast editor Dr. Amy Ross Russell to discuss their work. They describe the importance of the initial examination, from the patient's gait to difficulties in word retrieval. They also touch on challenges in the use of biomarkers, which drugs may be helpful, and how to advise patients and their carers. Read the paper: Dementia with Lewy bodies: a practical guide to clinical diagnosis and management Special thanks to The Podcast Studios Dublin for their assistance with the recording of this episode. (1) Tallaght Institute of Memory and Cognition, Tallaght University Hospital, Dublin, Ireland (2) Trinity College Dublin School of Medicine, Dublin, Ireland (3) Trinity College Dublin Academic Unit of Neurology, Dublin, Ireland Please subscribe to the Practical Neurology podcast on your favourite platform to get the latest episodes. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3vVPClm) or Spotify (https://spoti.fi/4baxjsQ). We'd love to hear your feedback on social media - @PracticalNeurol. This episode was hosted by PN's podcast editor Dr. Amy Ross Russell. Production by Amy Ross Russell and Brian O'Toole. Editing by Brian O'Toole. Thank you for listening.
Kamila Biedrzycka gości Tomasza Trelę z Nowej Lewicy, który bez owijania w bawełnę komentuje napięcia na linii Polska–USA. Trela MOCNO broni Włodzimierza Czarzastego, uderza w Donalda Trumpa i OSTRZEGA Karola Nawrockiego przed "LEWYM SIEROPOWYM". ŻĄDA też WYCOFANIA zaproszenia dla Skalika. Rozmowa o granicach sojuszu z Ameryką i pytaniu: sojusz czy polityczne poddaństwo? Posłuchaj! Oglądaj Express Biedrzyckiej na żywo w serwisie YouTube. Więcej informacji o programie na stronie Super Expressu.
Forwards forwards forwards… Every year we lose the gun mids with forward status yet, we are usually left with some solid value.. This year however, it feels the trickiest it has been to nail down 6 starting options that we are comfortable with in our starting squads.. To Sheez or not to Sheez? Can we pay up for premiums with an early bye? How many mid-pricers is too many? All this and more on the podcast this week!In this episode, the panel discusses everything you need to know in terms of the forward line. Lewy reveals his projected top 6 and the boys discuss who we can consider starting, the breakout guys are discussed in length as well as all the mid-priced guys who we may need to consider if the forward rookies don't present. We deliberately left this position until last to analyse to provide as much up to date information as possible, so this is not one to miss!The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Market Share Podcasts with Selby and Xavier Ellis Holmes Files episodes exclusive to the guide Much much more!The guide is now live! A must have for any serious Fantasy coach head over to moreirasmagic.com.au/ to order now! The guide will be updated right up until the start of round 1 and the in-season content beginsFollow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesysheroesLewy: @AFLewyHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsenaDossy: @HKdos
Is dementia the same thing as Alzheimer disease? Not exactly, and that difference can matter a lot when new symptoms show up.In this episode, Teepa Snow and Greg Phelps explain that dementia is an umbrella term and Alzheimer disease is one specific type of dementia under that umbrella. They then discuss the way that each form of dementia, with its specific pattern of brain change, can result in different real-life challenges—such as how visual hallucinations and frequent falls are far more common in some forms (like Lewy body dementia) and why sudden hallucinations in someone diagnosed with Alzheimer dementia may be a cue to look for something else that may be going on (illness, medication issues, etc.). In this episode, you'll learn:• What dementia means—and why it's not one single diagnosis• The basics of what's often typical in Alzheimer patterns over time • Why hallucinations, delusions, and sudden body changes can be important to noticeWant a deeper dive beyond today's episode? Watch Teepa's Understanding Different Dementias (12-part recorded series) to learn common patterns, changes to notice, and how your approach can shift based on the type of dementia.This podcast is educational and not medical advice. If symptoms change suddenly or feel urgent, consider contacting a licensed healthcare professional.This podcast is distributed on third-party platforms (including Spotify and Apple Podcasts) to make listening more accessible and convenient for our community. Our presence on any platform does not indicate endorsement of that platform, its owners, its policies, moderation decisions, advertising practices, or any other content hosted or shared there. The views and opinions expressed in this episode are those of the speakers and do not necessarily reflect the views of Positive Approach to Care® (PAC™).
Bails, Jordy & Lewy from The PODPOD take a look at Port Adelaide and their relevant players for the upcoming 2026 season!You can follow us on X @AFLFantasyFans or YouTube @AFLFantasyFanatics, & please subscribe wherever you listen to podcasts & give us a 5-star review!Thanks!
Honestly, what the ruck? Every year the rucks are one of the hardest lines to select in our AFL Fantasy starting squads. Jordy wants to “set and forget,” Lewy likes the idea of paying up for one and then finding value and Harmey genuinely has no idea where he wants to go. Come and join us as we talk all things rucks!In this episode, the panel discusses everything you need to know in terms of the ruck line. The lads discuss strategy and structure and whether you can or should pay up in the top tier with the impending ruck rule changes. They discuss allllllll relevant options they believe should be considered whilst chatting about whether it is viable to start a red dot rookie at R3. The decisions here will shape what money you have left to spend in other lines and is crucial in finding the balance that will set you up for success!The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Market Share Podcasts with Selby and Xavier Ellis Much much more!The guide is now live! A must have for any serious Fantasy coach head over to moreirasmagic.com.au/ to order now! The guide will be updated right up until the start of round 1 and the in-season content beginsFollow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesysheroesLewy: @AFLewyHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsenaDossy: @HKdos
Dr Sam Moxon, narrates his blog written for Dementia Researcher. In this blog, Sam reflects on the reality of Lewy body dementia through both his research background and his experience caring for his grandfather. He explores why LBD is so difficult to diagnose, how symptoms fluctuate, and how families are often left without clarity or closure. The piece speaks to the emotional weight of uncertainty and the importance of continuing to talk about LBD, not to find neat answers, but to help future families feel less alone. Find the original text, and narration here on our website. https://www.dementiaresearcher.nihr.ac.uk/blog-never-truly-known-the-reality-of-lewy-body-dementia/ -- Dr Sam Moxon is a biomaterials Research Fellow at University of Birmingham. His expertise falls on the interface between biology and engineering. His PhD focussed on regenerative medicine and he now works on trying to develop 3D bioprinting techniques with human stem cells, so that we better understand and treat degenerative diseases. Outside of the lab he hikes through the Lake District and is an expert on all things Disney. -- Enjoy listening and reading our blogs? We're always on the look out for new contributors, drop us a line and share your own research and careers advice dementiaresearcher@ucl.ac.uk This podcast is brought to you in association with the NIHR, Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Join our community: https://onelink.to/dementiaresearcher
Adam Smith narrates his post from the Dementia Researcher Community. In this post Adam reflects on conversations with carers who support people experiencing hallucinations, particularly in Lewy body dementia. Drawing on real encounters, he explores the uncertainty, emotional labour, and isolation that often sit beneath everyday care, and why awareness and shared understanding matter. Find the original text, and narration here on our website. https://communities.dementiaresearcher.nihr.ac.uk/c/research-chat/living-alongside-hallucinations-8379e5a8-9929-4b34-b5d5-033969892649 -- Adam Smith was born in the north, a long time ago. He wanted to write books, but ended up working in the NHS, and at the Department of Health. He is now Programme Director in the Office of the NIHR National Director for Dementia Research (which probably sounds more important than it is) at University College London. He has led a number of initiatives to improve dementia research (including this website, Join Dementia Research & ENRICH), as well as pursuing his own research interests. In his spare time, he grows vegetables, builds Lego & spends most of his time drinking too much coffee and squeezing technology into his house. -- Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Join our community: https://onelink.to/dementiaresearcher
When a patient says, "I biffed the car," how should that be translated? Puzzles like this represent the gap between description and diagnosis, and are a critical part of neurological practice. In this podcast for the February 2026 issue of Practical Neurology, editors Phil Smith and Geraint Fuller take turns decoding some of the mysteries of everyday neurology. They cover dementia with Lewy bodies, osteoporosis and fracture risk, and anxiety and depression in epilepsy patients, as a sample of some of the published work in the latest journal. There's also a guide to the latest stroke rehabilitation guidelines, freezing of gait, and a farewell to a 'nom de plume'. Read the issue: https://pn.bmj.com/content/26/1/1 Please subscribe to the Practical Neurology podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3vVPClm) or Spotify (https://spoti.fi/4baxjsQ). We'd love to hear your feedback on social media - @PracticalNeurol. Production and editing by Brian O'Toole. Thank you for listening.
Ajantha Abey narrates his blog written for Dementia Researcher. In this blog Ajantha reflects on why Lewy body disease deserves far greater attention within dementia research. Drawing on their journey from Alzheimer's focused tau research into synuclein pathology, the blog explores co occurring disease, diagnostic challenges, biomarker advances, and why understanding overlap across conditions is essential for better science and better care. Find the original text, and narration here on our website. https://www.dementiaresearcher.nihr.ac.uk/blog-alzheimers-to-lewy-body-disease-expanding-our-research-horizons/ -- Dr Ajantha Abey is a Postdoctoral Researcher in the Kavli Institute at University of Oxford. He is interested in the cellular mechanisms of Alzheimer's, Parkinson's, and other diseases of the ageing brain. Previously, having previoulsy explored neuropathology in dogs with dementia and potential stem cell replacement therapies. He now uses induced pluripotent stem cell derived neurons to try and model selective neuronal vulnerability: the phenomenon where some cells die but others remain resilient to neurodegenerative diseases. -- Enjoy listening and reading our blogs? We're always on the look out for new contributors, drop us a line and share your own research and careers advice dementiaresearcher@ucl.ac.uk This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Join our community: https://onelink.to/dementiaresearcher
It seems as though the midfield line is the last line being filled in our fantasy sides this year, with value presenting in defence and then the decisions to be made around the forwards and rucks. Some coaches are spending up in the mids, whilst others are looking at potentially 4 rookies on field! How you structure up will be crucial for success in AFL Fantasy this year! Don't worry, the lads talk through strategy and structure as well as all of the relevant starting options in the midfield!In this episode, the panel discusses everything you need to know in terms of the midfield line. Jordy gives who he thinks are the top 8 averaging midfielders broken down by tiers, the panel discusses the top end premiums who they believe still present upside, under-priced premiums who can hopefully take the next step and score in-line with the top 8 and then discuss a whole bunch of listener requests.The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Market Share Podcasts with Selby and Xavier Ellis Much much more!The guide is now live! A must have for any serious Fantasy coach head over to moreirasmagic.com.au/ to order now! The guide will be updated right up until the start of round 1 and the in-season content beginsFollow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesyheroesLewy: @AFLewyHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsenaDossy: @HKdos
Dr Peter Connelly narrates his blog written for Dementia Researcher. In this blog Peter explores how dementia with Lewy bodies can present very differently from other dementias, particularly in its early stages. Drawing on clinical experience, he outlines key features including sleep disturbance, hallucinations, movement changes, and fluctuating attention, and explains how careful observation during assessment can support earlier recognition. The piece also reflects on current treatment limitations and highlights opportunities for environmental and non drug interventions to inform future research and care practice. Find the original text, and narration here on our website. https://www.dementiaresearcher.nihr.ac.uk/blog-recognising-dementia-with-lewy-bodies-in-clinical-practice/ -- Dr Peter Connelly is a retired Old Age Psychiatrist who spent much of his career in Tayside, helping to establish clinical trials for dementia and neuroprogressive disorders in Scotland. Now working with the Scottish Neuroprogressive and Dementia Network, he combines professional insight with personal experience as a former carer. In retirement, he enjoys music, golf, and time with his grandchildren. -- Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social Join our community: https://onelink.to/dementiaresearcher
In this episode of the Dementia Researcher Podcast, we focus on Lewy body dementia and why it remains one of the most misunderstood and frequently misdiagnosed forms of dementia. Released ahead of Lewy Body Dementia Day on 28 January, the conversation explores what Lewy body dementia is, how it sits between existing diagnostic categories, and why it often takes years for people to receive the right diagnosis. -- Host Dr Sam Moxon is joined by three researchers working on Lewy body dementia from very different angles:
Today on Tech and Science Daily from The Standard, Alan Leer covers new UCL brain imaging research separating Parkinson's from Lewy body dementia, an Imperial-linked primate study on bonding behaviours, Which? calling for mandatory front-of-pack nutrition labels in the UK, NASA's early ISS Crew-11 return after a medical issue, plus Star Wars Outlaws landing on Xbox Game Pass and the latest Android security updates. Hosted on Acast. See acast.com/privacy for more information.
ad free at www.patreon.com/dopeypodcastThis Week on Dopey! Dave opens with a deeply personal and emotional tribute to Linda's father, Tony, who recently passed after a long battle with Lewy body dementia, and other ailments. He shares heartfelt memories of Tony's exceptional character—his strength, kindness, love of family, rock 'n' roll roots, teaching career, and unwavering positivity—reflecting on how Tony's compassion and support played a huge role in Dave's own recovery and relationship with Linda. The episode also touches on recent losses (Bob Weir of the Grateful Dead and actor James Ransone from The Wire), with Dave offering a half-hearted amend to Weir, pondering the future of Dead & Company, and urging listeners to reach out if struggling with depression. He then replays his powerful, candid interview with Alec Baldwin, where Alec gets brutally honest about his 40 years of sobriety, wild 80s cocaine-and-alcohol-fueled days in New York and LA, the terrifying overdose that led to his bottom, finding AA as his new “family,” the spiritual shift that kept him sober, and how the program carried him through massive personal and public storms (including his divorce and the Rust tragedy). All that and more on this weeks REPLAY! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Season 2025 has been and gone, with mixed results from the panel. Whether you were Holmesy who finished the competition in 2nd, or Harmey who finished in the Dossy ranks outside 10k, there are many lessons to be learned to help improve moving into 2026. On this episode, the lads bring learnings from 2025 as well as answer listener questions to help ensure we are all better Fantasy coaches in 2026.The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Podcasts with Selby and Xavier EllisHead over to moreirasmagic.com.au/membership to pre-order now - the guide will be released early January and updated right up until the start of round 1Follow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesyheroesLewy: @LewyAFHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsena
The Holmes Files is an in-depth strategy podcast where Holmesy interviews some of the brightest minds in the AFL Fantasy Community. Holmesy starts big, chatting with Kyerin Grundy who was the unofficial winner in 2025, before finding out after the comp was finished that he was ineligible for the hilux due to being the brother of the Ruck Pig Brodie Grundy.On this episode, Kyerin tells his story and reviews his epic 2025 season where he would end up as the #1 coach. The boys discuss starting squad philosophy, trades to win you the comp and much much more! This is a must listen for any coach who wants to compete at the top end!The PODPOD is brought to you by Moreira's Magic in 2026. All Holmes Files episodes will be available exclusively as a part of the 2026 Season Guide. As well as the podcasts, the Season Guide will also include: Player profiles and comments for all players in the AFL Best 22's from the MM team Draft rankings DVP Strength of schedule Podcasts with Selby and Xavier EllisHead over to moreirasmagic.com.au/membership to pre-order now - the guide will be released early January and updated right up until the start of round 1Follow us on X:The PODPOD: @podpodAFLHolmesy: @HolmesyheroesLewy: @LewyAFHarmey: @jonharmeyDos: @HKdosSam: @grillis03Jordy: @jordandsena
Het aantal mensen met cognitieve stoornissen neemt snel toe. In deze aflevering van Hersenspinsels spreken we met Edo Richard, neuroloog en hoogleraar in het Radboudumc en Amsterdam UMC, over hoe je als neuroloog omgaat met cognitieve stoornissen in de spreekkamer.We bespreken herkenning, diagnostiek en de nieuwste inzichten uit de richtlijn dementie. Denk aan het nut van NPO, MRI, liquor- en genetisch onderzoek, en de differentiaaldiagnose van Alzheimer tot frontotemporale dementie en Lewy body dementie. Ook komen behandelmogelijkheden aan bod – van medicatie tot psychosociale interventies.Tot slot laten we Edo niet ontsnappen aan een paar duivelse dilemma's: Gummbah of carnaval, MRI voor iedereen of werken met een assistent zonder klinisch kompas? Ook hoor je welk ochtendrapport cliché hij niet meer kan horen. Een aflevering boordevol klinische handvatten, praktische tips en nuance in een onderwerp dat voor elke neuroloog relevant is. Veel luisterplezier!
Gościem Melliny jest dziennikarz sportowy Sebastian Staszewski. Autor jednej z najgłośniejszych książek ostatniego roku "Lewandowski. Prawdziwy". Autor przedstawia biografię Robert Lewandowskiego, która przedstawia prawdziwy obraz jednego z najlepszych piłkarzy w historii. Dowiecie się m.in. że to żona Roberta namówiła go do zdrowego odżywiania, bo ten wcześniej bardzo lubił słodycze. Lewy miał też z nią poważną rozmowę na tematy publicznych występów tanecznych. Wokół gwiazdy futbolu narosło wiele legend. Komu Lewandowski nie chciał kupić kanapki, i komu odmówił pożyczenia pieniędzy? Lewandowski miał też wiele kompleksów na temat swojego wyglądu. Dziś wydaje się to nie do uwierzenia. Jaki naprawdę jest Robert Lewandowski o tym w najnowszej rozmowie z Marcinem Mellerem.
Lize Lewy didn't mean to get a scene-stealing role in the Rep's latest production. The Webster grad tells KMOX how she landed on center stage.
L'un des faits les plus surprenants dans l'interprétation scientifique des rêves ne concerne ni les symboles, ni la psychanalyse, mais notre corps lui-même. De nombreuses études montrent aujourd'hui que certains rêves peuvent révéler une maladie avant même que les premiers symptômes ne se manifestent. Ce phénomène, longtemps relégué aux anecdotes, est désormais documenté par la recherche en neuropsychologie et en médecine du sommeil.L'exemple le plus fascinant vient d'une étude publiée dans The Lancet Neurology. Des chercheurs s'intéressaient au trouble du comportement en sommeil paradoxal (TCSP), une affection dans laquelle les dormeurs “vivent” leurs rêves : ils parlent, crient, donnent des coups, ou se débattent comme s'ils étaient réellement dans la scène rêvée. Ce trouble provient d'un dysfonctionnement du cerveau : durant le rêve, les muscles ne sont plus paralysés comme ils devraient l'être. Mais l'élément troublant va plus loin.Les scientifiques ont découvert que jusqu'à 80 % des personnes atteintes de ce trouble développent dans les années qui suivent une maladie neurodégénérative, notamment la maladie de Parkinson ou une démence à corps de Lewy. Le rêve devient alors un signal d'alerte neurologique, une sorte de message avant-coureur envoyé par un cerveau déjà en difficulté, bien avant l'apparition des symptômes cliniques tels que les tremblements ou les pertes de mémoire.Pourquoi ? Parce que les régions cérébrales qui contrôlent le rêve et la paralysie musculaire — notamment le tronc cérébral — sont les premières touchées par les dépôts anormaux de protéines responsables de ces maladies. Autrement dit, le cerveau annonce sa propre souffrance… dans le rêve.Un autre aspect étonnant : certains patients commencent à rêver de situations de danger extrême — être poursuivi, attaqué, agressé — alors qu'ils n'avaient jamais ce type de rêves auparavant. Ces scénarios ne traduisent pas une angoisse psychologique, mais un signal biologique : les circuits neuronaux régulant la peur deviennent instables, ce qui peut annoncer une maladie en développement.Ce phénomène bouleverse l'idée traditionnelle du rêve comme simple reflet de l'inconscient. Il montre que le rêve est aussi un outil diagnostique potentiel, capable d'indiquer des troubles invisibles à l'examen médical classique.Ainsi, l'un des faits les plus étonnants de la science du sommeil est que nos rêves peuvent parfois prédire une maladie, et le faire avec une précision qui intrigue de plus en plus les chercheurs. Le rêve n'est peut-être pas un oracle… mais il est clairement un capteur avancé de notre santé. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
We're back with another episode of A (Non) League Of Their Own! Join us every Wednesday at 5pm where we discuss the best Non-League stories from up & down the country, from The National League to The Dog & Duck & everything in between. This week we were joined by our usual trio of Gaz, Jordan & Lewy as well as returning favourite Gary Stopforth to discuss this weekend's non league stories including G Stop's big announcement, the best Premier League players to play in non-league & fans throwing objects onto the pitch. We also talked about pitch walk ons, more football fights, the lads penalty records & the news that Maidenhead legend Alan Devonshire has resigned from the club. Learn more about your ad choices. Visit podcastchoices.com/adchoices
We're back with another episode of A (Non) League Of Their Own! Join us every Wednesday at 5pm where we discuss the best Non-League stories from up & down the country, from The National League to The Dog & Duck & everything in between. This week we were joined by our usual trio of Gaz, Jordan & Lewy as well as podcast debutant & Radcliffe coach Craig Doble to discuss this weekend's non league stories including Jordan being sent off for diving, fighting in vets football & how much money do non-league players actually earn? We also talked about Chorley's incredible Christmas gesture, non-footballing injuries, banning shin pads & finally should players refund fans after a heavy defeat?
I lost my grandmother a few weeks ago to Lewy-body dementia. Actually, that's not true, I lost her over 15 years ago, but now I get my mom back, she was her caregiver for 13 years.
Dr. Jason Crowell and Dr. YuHong Fu discuss the importance of differentiating between dementia with Lewy bodies and Parkinson disease dementia. Show citatiion: Fu Y, Halliday GM. Dementia with Lewy bodies and Parkinson disease dementia - the same or different and is it important?. Nat Rev Neurol. 2025;21(7):394-403. doi:10.1038/s41582-025-01090-x
Dr. Jason Crowell talks with Dr. YuHong Fu about the importance of differentiating between dementia with Lewy bodies and Parkinson disease dementia. Read the related article in Nature. Disclosures can be found at Neurology.org.
We're back with another episode of A (Non) League Of Their Own! Join us every Wednesday at 5pm where we discuss the best Non-League stories from up & down the country, from The National League to The Dog & Duck & everything in between. This week we were joined by Lewy & Jordan as well as returning favourite Grant Shenton and channel newcomer Rick Smith to discuss this weekend's non league stories including how many low league footballers admit to playing hungover, pre-match habits & Robbie Savage's rise as a football manager. We also talked about Litherland REMYCA's 21 game losing streak, Jordan Ibe back enjoying his football and the experience of winning the FA Vase.
Another week, another episode of A (Non) League Of Their Own! Join us every Wednesday at 5pm where we discuss the best Non-League stories from up & down the country, from The National League to The Dog & Duck & everything in between. This week we were joined by the usual trio of Gaz, Jordan and Lewy and following on from Phenix last week we had another I Had Trials Onces legend join us...Gary Stopforth sat down to discuss this weekend's non league stories including the player sent off for going to the toilet, Jordan's football manager ratings & Mark Hughes love for the game. We also spoke about the Welsh go karting cup draw, dealing with refs & fans as well as AI Footballers in non-league?
Synucleinopathies are a group of age-related neurological disorders, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Most individuals are not diagnosed until these diseases have significantly progressed, as early symptoms, such as a reduced sense of smell, subtle cognitive or motor changes are too vague to serve as reliable indicators. To uncover specific biological signs that appear earlier and clearly point to the disease process, researchers from Saarland University developed a study titled “Brain region-specific and systemic transcriptomic alterations in a human alpha-synuclein overexpressing rat model,” featured as the cover Aging-US, Volume 17, Issue 10. Full blog - https://aging-us.org/2025/11/alpha-synuclein-overexpression-in-rats-reveals-early-clues-to-synucleinopathies/ Paper DOI - https://doi.org/10.18632/aging.206331 Corresponding author - Thomas Hentrich - thomas.hentrich@uni-saarland.de Abstract video - https://www.youtube.com/watch?v=Yl6AfVchkb0 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206331 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, alpha-synuclein, transgenic rat model, different brain regions, transcriptome analysis To learn more about the journal, please visit https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@Aging-US LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
¡Vuelve Team Barça Podcast con una nueva entrega repleta de fútbol y emociones! El Barça ganó 2-4 en Balaídos con hat-trick de Lewandowski, que a sus 37 años firmó una exhibición de profesionalidad y eficacia. Juanma, Tony y César analizan el partido y charlamos con Roger Bonet “Ruxi”, poniendo el foco en la presión, la respuesta colectiva y el momento de forma de los de Flick. Además, comentamos el regreso de Lionel Messi al Camp Nou y cerramos con una charla junto a Oriol Domènech para repasar la actualidad del Barça Atlètic, su momento en Segunda RFEF y los jóvenes que piden paso. ⏰ BLOQUES DEL EPISODIO: 00:00 | Sintonía TBP 01:27 | Editorial «Dziękuję, Robert» 05:30 | Tertulia Celta 2-4 Barça con Juanma, Tony y César 13:23 | Charlamos con Roger Bonet sobre el Barça de Flick 35:38 | El ejemplo de Lewandowski y su exhibición en Balaídos 46:11 | Los puntos TBP del Celta 2-4 Barça 1.09:10 | Del regreso de Messi al Camp Nou 1:22:25 | El Barça Atlètic con Oriol Domènech 1:42:31 | Despedida y cierra Contenido exclusivo y apoyo: • Hazte socio en Patreon teambarca.com/patreon • Fan en iVoox (1,49 €/mes sin publicidad) • Invítanos un café ☕️ ko-fi.com/teambarcapod Colabora con TBP: Betbrothers → https://betbrothers.es/?utm_source=page&utm_medium=cta&utm_campaign=n0001&utm_id=0001 Participa: • Fantasy Biwenger https://biwenger.as.com/go/team-barca-podcast-26 • Encuesta TBP https://bit.ly/EncuestaTBP Tienda oficial https://www.teambarca.com/tienda Conecta: X @TeamBarcaPod Telegram bit.ly/ChatTBP Discord bit.ly/DiscordTBP Contacto oyentes@teambarca.com Música: Jamendo.com
Acting out dreams during sleep is an early warning sign of Parkinson's or dementia with Lewy bodies, offering a window for early detection and prevention Advanced MRI scans now reveal that your brain's waste-clearing system slows down years before symptoms like tremors, stiffness, or memory loss appear One study found that people with impaired brain waste clearance were more likely to develop Parkinson's, while another discovered that excess fluid between brain cells predicted future dementia These findings show that subtle changes in brain fluid balance — not just loss of dopamine or brain shrinkage — predict who develops neurodegenerative disease and how fast it progresses Supporting your brain's "cleaning system" through deep sleep, regular movement, hydration, and toxin avoidance helps protect memory, balance, and mental clarity for life
La matière noire se plie à la gravité classique, selon une étude genevoise Les brèves du jour Syndrome de Korsakoff : trouble cognitif dû à l'alcool et au manque de vitamine B1 Maladie à corps de Lewy, l'autre grande démence méconnue En direct de Dakar : quand le sport devient levier de santé
TWiN explains epidemiological data showing that exposure to air pollution was associated with an increased risk of developing Lewy body dementia, and nasal administration of air pollution in mice led to brain atrophy and impaired cognition and motor function. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Links between air pollution and dementias (Science) Letter from Susan Schneider Williams Widow of Robin Williams (Lewy Body Dementia UK) Awakenings (Wikipedia) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv
La princesa Leonor gana protagonismo, con Felipe VI cediendo el protagonismo de los discursos. Se intensifican los debates en la UE sobre la oficialidad del catalán, el gallego y el euskera. Junts per Catalunya evalúa su apoyo al gobierno. Se aborda el deterioro cognitivo leve, distinguiéndolo de la demencia y sus tipos: vascular, cuerpos de Lewy, frontotemporal y la asociada al Parkinson. La detección temprana y un estilo de vida saludable son claves. Se detallan los síntomas de cada tipo de demencia y la importancia de la familia en su gestión. Un experto en COPE subraya que el deterioro cognitivo no significa siempre demencia y que la memoria reciente es la más afectada por la edad. En deportes, la Real Sociedad gana al Sevilla, la selección femenina de fútbol vence a Suecia. Se relata la historia de Camino, una nadadora con síndrome de Down que supera barreras y aspira a los Juegos Paralímpicos. Se analiza el fenómeno de los "bulos" en comunicación, destacando que son información ...
In a world where dementia affects millions, the narrative often leans toward loss and isolation. But what if communities could rewrite that story—one where people living with dementia not only survive but thrive, connected and included? That's the heart of the Dementia Friendly Nevada (DFNV) initiative, and few voices capture its urgency and hope like Casey Venturini, director of DFNV and a passionate advocate shaped by personal experience.In an interview with Steve Gurney of the Positive Aging Community, Venturini shared his journey from family care partner to national leader in dementia inclusion. His story isn't just inspirational; it's a call to action for communities everywhere. From Personal Loss to Professional PurposeVenturini's entry into this work was deeply personal. Growing up in a multigenerational household, he was as close to his grandparents as his parents. At age 11, his grandfather was diagnosed with Lewy body dementia, which significantly impacted his final years. The diagnosis felt like a door slamming shut. The community seemed to withdraw, leaving his grandfather isolated in a slow, tragic decline—mirroring the Hollywood tropes of inevitable goodbye. This revelation transformed his view. Today, his grandmother lives with dementia in New York, supported by a network that embraces possibility over pity. "She's not suffering with dementia. She is living her life with dementia," Venturini explained. It's a stark contrast to his grandfather's experience, underscoring how knowledge and community support can turn challenge into chapters of growth.This grassroots approach recognizes that dementia-friendly work isn't one-size-fits-all. Each community brings unique strengths and needs, making the movement a "collaborative learning effort" under the national umbrella of Dementia Friendly America, which has thrived for nearly a decade.The Core Values: An Ethical Roadmap for InclusionAt the soul of DFNV are eight shared values, collaboratively crafted with people living with dementia, care partners, and professionals. Presented to the Nevada Legislature in 2017 by someone living with dementia, these principles frame dementia-friendly efforts as "citizenship work"—calling for full societal engagement, not just dementia-related programming.People can live well with dementia. Hope is foundational; without it, opportunities for well-being vanish.Partnering with people living with dementia and honoring each individual's lived experience opens a world of possibilities. People with lived experience of dementia are the true experts, in this work, co-leading—not just participating in—dementia-friendly and inclusive initiatives.Recognizing, validating, and responding to all forms of expression as meaningful communication supports well-being. Communication evolves; assuming intent behind every word and action builds deeper connections.When supporting a person living with dementia, we should always strive to see the world from their perspective.People living with dementia have the right to freedom. Diagnosis doesn't strip away autonomy; communities must safeguard choice.People living with dementia can grow and thrive. A diagnosis marks a new chapter, a comma not a period, and a life with dementia can be a life of meaning, growth, and joy with the right support. Proactive supports and services reduce the need for reactive interventions. Upstream conversations across sectors prevent crises and cut costs.A dementia-inclusive community is a strong community; everyone needs community, and communities need everyone. Inclusion benefits all, fostering connected, resilient societies.Venturini's work emphasizes collaboration, echoing a key model from Dupuis, Gillies, Carson, et al. (2012): the "Authentic Partnerships" framework. For more information visit https://dfamerica.org/
In this episode of the Let's Talk Brain Health Podcast, we welcome Dr. Kellyann Niotis, MD, the world's first fellowship-trained preventive neurologist, who shares her insights on early detection and risk reduction for neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Lewy body dementia. Dr. Niotis discusses the emerging field of preventive neurology, the role of blood biomarkers and genetic testing, and the importance of lifestyle choices in maintaining brain health. She also highlights the impact of cholesterol management, sleep studies, and the significance of personalized care approaches. Join us as we dive into a comprehensive discussion about the future of brain health and the proactive steps we can take today for healthier brains tomorrow.00:00 Introduction to Dr. Kellyann Niotis, MD02:47 What is Preventive Neurology?06:08 The Role of Biomarkers in Early Detection13:52 Lifestyle Modifications and Brain Health17:12 Cholesterol and Brain Health24:15 The Impact of Statins on Cognition26:05 Underutilized Tools in Brain Health30:11 Rapid Fire Questions and Final ThoughtsResourcesConnect with Kellyann on Instagram @drkellyannniotis Visit her website and learn more about her new clinic on their websiteResearchLearn more about the research-informed brain health risks mentioned in this episode from the “Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission” ReportRead more about Dr. Lisa Misconi's research on how estrogen receptors are unregulated in perimenopause in this research article
There is an important role for cost-effective clinical biomarkers in the diagnosis of Parkinson's disease. Dr. Eduardo de Pablo-Fernández and Dr. Cecilia Tremblay discuss how accurate hyposmia and REM sleep behavior disorder can predict Lewy pathology in a non-selected population using data from the Arizona clinicopathological study on Aging and Neurodegeneration. Read the article.
Lewy body dementia affects over a million people in the United States, but many people don't know much about it. It's difficult to diagnose and often misdiagnosed. A new documentary called “Facing the Wind” shines a light on Lewy body dementia, both living with it and caring for someone who has the disease. Racquel Williams talks with Philadelphia filmmaker Tony Heriza and Linda Szypula, who lives in Plymouth Meeting and whose journey caring for her husband is featured in the film. Scribe Video Center is hosting a screening of “Facing the Wind” on September 18. Listen to Linda's podcast, “Lewy Body Roller Coaster”, here. Then, on Shara in the City, Marsha's - Philly's first queer women's sports bar - is set to open on South Street on September 19. Shara Dae Howard visits with the owner to hear about her inspiration for the bar and what's to come. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
When Greg asks about the different types of dementia, Teepa reveals there are anywhere from 120 to 220 different forms—and she explains why you don't need to memorize them all. She shares a lifesaving example of how knowing just one key detail about Lewy body dementia can help prevent irreversible damage from a commonly-prescribed medication.
In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a promising blood test to distinguish Parkinson's disease from dementia with Lewy bodies, how CAR T-cell therapies are showing potential for patients with glioblastoma, and a new wireless electroencephalogram device that can even monitor young children with epilepsy.
In this episode, we explore how nonprofit organizations like LBDA are working alongside industry partners to shape the evolving landscape of dementia biomarkers—bridging scientific innovation with real-world care. Featuring an engaging conversation with Dr. Sudhir Sivakumaran, Dr. Kathleen Poston, and Dr. Dustin Dunham on clinical utility, patient-centered research, and the road to broader adoption of biomarkers in Lewy body dementia, Alzheimer's disease and related disorders. This episode is sponsored by GE HealthCare
Presidential advisor and former News Hour contributor David Gergen died at 83 after being diagnosed with Lewy body dementia. Throughout his career, Gergen served four presidents, both Democrats and Republicans, and he spent many Friday nights offering his insights and analysis here on the MacNeil/Lehrer NewsHour. Geoff Bennett has this remembrance. PBS News is supported by - https://www.pbs.org/newshour/about/funders