Podcasts about Human Research Program

In this weeks episode of "Pushing the Limits" , Dr. David Furman, Director of the 1000 immunomes project, the world's largest longitudinal population-based study of immunology and aging at Stanford University and Associate Professor at the Buck Institute for Aging, Founder of Edifice Health and Cosmica Biosciences, discusses his extensive research in immunology, particularly focusing on the 1000 Immunomes Project, which aims to understand the immune system's role in aging.  He emphasizes the importance of studying human biology over traditional animal models and introduces the concept of the Inflammation Age Clock as a new biomarker for aging.  The discussion also covers the implications of systemic chronic inflammation in aging, the role of nutrition, and the potential for interventions to improve health span. Additionally, Dr. Furman shares insights into his work with NASA on accelerated aging in astronauts, highlighting the broader applications of his research in combating age-related diseases.   Takeaways:    Dr. Furman aims to have a massive impact on human health. The immune system plays a crucial role in aging. Human studies provide better insights than animal models. The Inflammation Age Clock is a new biomarker for aging. Chronic inflammation is a key factor in age-related diseases. Nutrition significantly affects inflammation and aging. Reliable biomarkers are needed for effective aging interventions. NASA's research on astronauts reveals accelerated aging in space. The convergence of technologies is revolutionizing health research. Future research will focus on protecting astronauts and advancing aging studies. Titles: System Chronic Inflammation: The Hidden Driver of Aging Nutrition and Inflammation: Key Factors in Health span   About the 1000 immunomes Project: The Stanford 1000 Immunomes Project (KIP) is a collaborative ongoing study at Stanford University that aims to define the biological basis of aging and disease using state-of-the-art 'omics' platforms and advanced artificial intelligence (AI) methods. The main focus of 1KIP is to establish biomarkers for healthy versus sub-functional immune systems. They do this by identifying the interactions between genetic and environmental factors, which contribute to the observed heterogeneity of biological responses in human beings.  To this end, 1000 individuals of different age groups (9-96 years old) were recruited between 2007-2017. Their blood samples were screened using multiple state-of-the-art technologies at a single facility, the Human Immune Monitoring Center (HIMC) to measure circulating proteins, cell types, cellular functions, whole-genome blood gene expression and subjects' haplotypes using deep sequencing technologies. The 1KIP dataset has enabled us for the first time to identify reliable biomarkers of aging and disease in a longitudinal population-based study of immunology and aging. 1KIP provides reference values for thousands of immune variables and identifies clusters of individuals sharing similar health versus disease immune profiles. BIO Dr. David Furman is an academic entrepreneur deeply committed to addressing intricate challenges within human biology, systems medicine, translational immunology, preventative healthcare, aging, and precision longevity. Holding positions as the Director of the Stanford 1000 Immunomes Project at the Stanford School of Medicine and as an Associate Professor and Director of the Bioinformatics and Data Science Core at the Buck Institute for Research on Aging, Dr. Furman leads research endeavors that leverage multi-scale biology ('omics') platforms and advanced AI/ML methodologies. He identifies biomarkers and integrative biological clocks essential for monitoring individual health statuses. Groundbreaking technologies originating from the Furman lab now facilitate the application of descriptive and mechanistic biomarkers to detect and combat accelerated aging and disease progression. With over 15 years of specialization in inflammation's role in aging mechanisms, Dr. Furman's expertise includes various domains, including neuroscience, cardiovascular health, metabolic diseases, and immune system function. Notably, in 2022, NASA's Human Research Program sought Dr. Furman's collaboration, leading to partnerships with SpaceX and Cornell University. Dr. Furman's entrepreneurial initiatives include the founding of the Inflammaging Institute, aimed at democratizing biological aging diagnosis, and the establishment of Stanford spin-off Edifice Health Inc., and Buck Institute spin-off Cosmica Biosciences Inc., both focused on innovative approaches to combat aging-related ailments and precision longevity interventions. Dr. Furman has published over 50 scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others, and is the inventor of over 25 patents.     Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with:  Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals  Nutristat Omega 3 to 6 status and more  Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa    Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.  Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to  Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to  https://www.buymeacoffee.com/LisaT to donate $3   Lisa's Anti-Aging and Longevity Supplements  Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.  This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.   Subscribe to our popular Youtube channel  with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube   Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"  Check them all out at  https://shop.lisatamati.com/collections/books   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here:    Use code "tamati" at checkout to get a 10% discount on any of their devices.   Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38   Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off     Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts.  To pushing the limits, Lisa and team

Today we have the former chief scientist of NASA's Human Research Program, Dr. Mark Shelhamer. Mark specializes in neurovestibular adaptation to spaceflight. He is an otolaryngology professor at Johns Hopkins School of Medicine and the director of the school's Human Spaceflight Lab. He also the director and founder of the Bioastronautics at Hopkins initiative. In addition to his work with NASA, Mark is an advisor to the commercial and consumer spaceflight industry. In today's interview, we talk to Mark about some of this work, as well as the research he conducted on the first all-civilian crew that successfully orbited the Earth for three days in a SpaceX capsule. We mostly talk to Mark, however, about how the harsh conditions of space imperil humans. We have a fascinating discussion about Mark's role in NASA's planned human mission to Mars and how he is investigating ways to maintain the health and performance of astronauts on such a long-duration spaceflight.  We also discuss how the lessons Mark is learning about how the lessons of human spaceflight can be applied to healthcare on Earth. Show notes: [00:02:42] Dawn starts the interview mentioning that Mark grew up in Philadelphia in the ‘70s. She asks Mark what he was like as a kid. [00:03:32] Dawn asks if it is true that Mark played drums in a band in school. [00:03:54] Ken asks Mark to talk about an uncle who was key in fostering Mark's interest in math and science. [00:05:31] Ken mentions that Mark was only 10 years old when he took up an interest in electronics and asks what sparked that and what electronics he specifically found interesting. [00:08:14] Dawn mentions that Mark attended Drexel University and initially wanted to become an electrical engineer but changed his mind somewhere along the way. Dawn asks what caused this shift. [00:10:20] Ken asks Mark why he selected to attend MIT after Drexel. [00:13:52] Ken asks Mark how he ended up at Johns Hopkins after finishing his studies at MIT. [00:15:52] Dawn mentions that when Mark arrived at Johns Hopkins as a postdoc fellow in 1990, he continued the research he had been doing at MIT on sensory motor physiology and modeling, including astronaut adaptation to space flight. Dawn asks Mark to give an overview of this research as well as how he tracked back into studying astronauts. [00:17:15] Ken mentions Mark's 2007 book “Nonlinear Dynamics in Physiology: A State-Space Approach,” which provides mathematical-computational tools for analyzing experimental data. Ken asks Mark to talk about the book and its goals. [00:20:43] Ken mentions that Mark has done quite a bit of research into motion sickness and vestibular issues, and asks about his more recent work on Space Motion Sickness. [00:24:53] Dawn explains that on Mark's Wikipedia page, there's a reference to his pioneering work on a multidisciplinary approach to human space flight research. She asks Mark to give an overview of this work. [00:29:17] Dawn explains that spaceflight has widespread effects on many different body systems at the same time, and that Mark has been an advocate for developing approaches to examining all these interactions in a rigorous way. Dawn asks if Mark feels that we should be taking this rigorous multidisciplinary approach and applying it to terrestrial medicine as well. [00:34:08] Ken asks Mark to talk about some of the progress he has made in convincing certain groups that they need to embrace a multidisciplinary approach to their research. [00:38:37] Dawn mentions that getting people, especially groups, to change their approach to research can be a daunting task. She goes on to mention that Mark has been quoted as saying “If there's one thing I'm known for, it's banging my head against the wall trying to convince people to do integrative research.” Dawn asks Mark how many scars he has on his forehead from these efforts. [00:43:00] Dawn asks Mark to talk about his informal experti...

Episode 134: Martian Medicine 101.    Future doctor Collins and Dr. Arreaza talk about the health risks of going to space and to Mars, especially the effect of radiation. Written by Wendy Collins, MSIII, Ross University School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Today is March 31, 2023.Arreaza: Wendy, I confess I am excited for today's topic. My love for space began with E.T. (I know, I am old). I was exposed to that famous movie when I was a little kid, and ever since, I have had a tremendous curiosity about space and Mars. Honestly, I did not think this could be a topic for our podcast until I met you. Wendy: I got inspired to talk about space medicine because I want to go into this field. My college degree was in Physics, and I was fortunate to do Astrophysics and Particle Physics research as an undergraduate, as well as coral reef research. I am passionate about Medicine and treating patients, but I also love Aerospace Medicine because it's so interdisciplinary. Flight surgeons get to scuba dive, work on oceanography, botany, engineering projects, and more, and collaborations like that sound exciting to me. Anyways let us talk about what is going on in the industry right now. Dr. Arreaza, do you know what humans are doing in space this year?Arreaza: I do! I like to watch the launches online and in person. I have seen several SpaceX rockets from my backyard (something I never imagined I could do), and there has been some big news, we are going back to the moon! Wendy: Yes! Artemis 1 was a successful unmanned mission to orbit the moon and it was launched in November and landed in December last year. Now we look to Artemis 2, which will be a manned lunar flyby. So, like Artemis 1, but with astronauts onboard. And the goal for future missions after that is to land on the moon, establish a lunar base, and eventually prepare us for a long-term space flight like that to Mars. And there is even a presidential order to land humans on Mars by 2033. Arreaza: Yes, it is very exciting! BUT there are many, many human health risks to space flight.Wendy: Even more for space flight outside of low earth orbit. Because of this, and because space flight is becoming commercialized, space medicine is a growing field, and growing in all medical specialties. Believe it or not, I was just in a talk by a NASA flight surgeon where it was mentioned that NASA is even looking for OB/GYN because 50% of their astronauts are women who need gynecological care, and they currently have to go off-site to receive it.Arreaza: That's so cool! I've read of a handful of civilian and military aerospace medicine training programs for physicians after residency. And since we're in Bakersfield and only a stone's throw away from this campus, why don't we briefly mention the University of California Los Angeles?Wendy: Yes, so UCLA established an aerospace fellowship very recently in 2021. That fellowship, unlike the rest of them, is actually for board-certified emergency medicine physicians only right now, I believe the only one that does not consider other specialties like internal medicine and family medicine, but the program is new so who knows that may change. The fellowship's goal is to train the next generation of space flight surgeons. Part of the medical training includes working in arctic environments, Mars analog missions, which includes rotations at SpaceX and NASA's jet propulsion laboratory. There are so many new avenues to pursue education and jobs in aerospace medicine but today we're focusing on some research that's near and dear, and revolves around how we get to Mars in one piece. You may ask, what are the health risks of going to Mars? Ultimately, I would like to chat about how we mitigate those risks, but first let's define them.Arreaza: So, we got some ideas from a paper published in 2020 by Patel et al. It is titled: Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars. Let's begin.Wendy: Spaceflight is dangerous with unique risks and challenges. As a space flight surgeon, your job revolves around ensuring the overall safety of the crew, as well as their physical and mental health and well-being. The major health hazards include radiation, altered gravity fields, and long periods of isolation and confinement. Each of these threats is associated with its own set of physiological and performance risks to the crew.Arreaza: But crews do not experience stressors independently, so it is important to also consider their combined impact. NASA's Human Research Program researches over 30 categories of health risks astronauts can face with space flight.Wendy: Yes, but this article only discusses 4 of those categories, but don't worry, they are the biggies, they are the “Red Risks.”Arreaza: So, what are Red Risks?Wendy: Red Risks are risks that are considered the highest priority due to their greatest likelihood of happening and because they are most detrimental to the crew's health and performance, which impacts the success of the mission.Arreaza: There also exists “yellow” and “green” risks too, which of course are important, but less severe or less likely to occur than the Red Risks. Wendy: I just want to say I really like the title of this paper. Red risks for a journey to a red planet because Mars of course is red. Anyways as part of this paper, the “red risks” we are going to cover are space radiation health risks. This paper also covers spaceflight-Associated Neuro-ocular Syndrome, which is also known as SANS, behavioral health and performance, and inadequate food and nutrition. But today, we are only going to cover radiation health risks. But one thing this article did not discuss was the human health risk of infection, so let's briefly mention it now. Arreaza: Yes, I can imagine spacecrafts are not sterile environments. It would be important to mitigate infections and hygiene necessities and have antibiotics that are functional and not expired or altered by radiation. Alright let's start with the first health risk on the list, radiation.Wendy: Space radiation health risk is a large topic because it does not just predispose you to cancer, it also affects many organ systems. So, we are going to break down the health risks caused by space radiation exposure into of course radiation carcinogenesis, but also cardiovascular disease, degenerative tissue effects, and lastly acute in-flight as well as late central nervous system effects. Arreaza:Wendy: Yes the spacecraft does filter some radiation of course, but not Earth's atmosphere. It's actually a common misconception that astronauts on the International Space Station are protected by Earth's atmosphere. But it's not the atmosphere, it's Earth's magnetosphere, which is protective from radiation on some level because it absorbs many high-energy protons from space that, if not absorbed, would interact and cause damage to whatever is around. Arreaza: But astronauts on the ISS are exposed to radiation, how much?Wendy: So, about one weekon the ISS is approximately equivalent to one year's exposure to radiation on the ground. But astronauts going to Mars are going to be in space a lot longer than one week. NASA's 2020 Perseverance rover mission took 7 months to get to Mars.Arreaza: And that's without Earth's magnetosphere, and not considering any travel back home. That's a lot of radiation. How much radiation exposure would you get traveling to Mars?Wendy: The crew to Mars would be exposed to pervasive, low dose-rate galactic cosmic rays, and to intermittent solar particle events. Arreaza: Wow galactic cosmic rays?Wendy: Yeah, they sound cool but they're not the ones that give us superpowers like in the Fantastic Four. It means high charge and high energy protons will come into contact with the spacecraft and all the things inside. While the spacecraft will act as a shield, it will never be an entirely perfect shield and protons will penetrate and interact with human tissues, and you know what that means Dr. Arreaza…Arreaza: DNA breaks which can cause diseases including cancer, cardiovascular and neurologic disorders. Wendy: Exactly. It's important to note there are so many variables including the spacecraft design, what's happening with the sun, and the duration of the trip. And because of all these things, the risk assessment for radiation exposure is difficult to pinpoint because it's truly going somewhere we've never gone before. The types of radiation encountered in space are very different from the types of radiation exposure we are familiar with here on Earth. There have been radiobiology experiments working on simulating space radiation here on Earth, but we still lack reliable human data.Arreaza: Interestingly, the astronaut with the longest space flight, a Russian physician astronaut Dr. Valeri Polyakov, was on the ISS for 437 days. Dr. Polyakov recently passed away. His cause of death is not disclosed, but he lived a long life into his 80s, so at least we know he did not get terminal cancer after all that time in space.Wendy: Yes, and that was just Dr. Polyakov's longest flight. He was on five different Soyuz missions and 2 MIR missions. So, there will be radiation no matter what, what can be done about it?Arreaza: There's ongoing research focused on age, sex, and health of the astronaut. Not all people are affected by radiation the same way. Biomarkers are being investigated to determine who will be less sensitive to radiation.Wendy: Exactly just like we have biomarkers to know if you are predisposed to developing cancers. But back to space.The major cancers of concern from space radiation are epithelial in origin, particularly lung, breast, stomach, colon, and bladder, and leukemias. Radiation is a “red risk” also because of the likelihood of developing cancer after the mission back on Earth. Dr. Polyakov was fortunate to live a long life, but what about our Mars astronauts with even greater radiation exposure?Arreaza: This research paper even mentions cancer is a long-term health risk and although it is rated as “red”, most research in this area is currently delayed. This is because NASA's Human Research Program is focusing on in-mission risks, not the risks after the mission. But research is still being done to establish radiation dose thresholds, specifically permissible exposure limits. Wendy: So now let us talk about the effects of radiation that is not cancer.Arreaza: So, we know radiation can cause many other health problems. This includes cardiovascular and cerebrovascular diseases, cataracts, digestive and endocrine disorders, immune deficiencies, and respiratory dysfunction. Wendy: Specifically, we know cancer patients who have received high-dose radiation to the mediastinum, are at an increased risk for cardiovascular disease including heart attack and stroke. An astronaut who goes to Mars is more likely to die from a heart or vascular disease secondary to radiation than cancer.Arreaza: NASA also is concerned about the effects of other inflight risks such as more blood flow to your head without the effect of gravity. Not to mention developing atherosclerosis, myocardial infarction, stroke, or arrhythmia just like anybody else on Earth.Wendy: There is also chronic inflammation and increased oxidative stress from radiation, which contributes to cardiovascular disease. For example, the mechanism of increased endothelial dysfunction.Arreaza: Health problems are not only a result of spaceflight but there can be pre-existing conditions. Astronauts are extensively screened medically, but diseases can also arise in astronauts who are “healthy” before leaving. Wendy: Absolutely, which is why right now only extremely healthy individuals are candidates to become astronauts, although this will likely change as space becomes more accessible the more spaceflight commercializes.Arreaza: Other diseases induced by radiation include CNS effects. Acute CNS problems that may arise during flight are impaired cognitive function, motor function, and behavioral changes. These would cause serious problems for astronauts.Wendy: Besides acute, there are also chronic CNS problems. This includes Alzheimer's disease, dementia, or accelerated aging. This has been shown with rodents exposed to radiation in which neurons and neural circuits change causing performance deficits.Arreaza: It is important to note that no astronauts have suffered from life-changing radiation damage illnesses to date.Wendy: Again, back to Dr. Polyakov is evidence of that. And again, more research needs to be done to understand the significance of radiation to human health and determine how much radiation is too much radiation.Arreaza: That was Martian Medicine 101. Why are we talking about space medicine in this podcast?Wendy: Space medicine might be an out-there topic for our Family Medicine podcast. But going into space has given us technologies that help us in our day-to-day in life for non-medical folks, but also for primary care staff. The aural thermometer that takes your temperature by being placed near your ear was developed by NASA. Also, ventricular assist devices LASIK, cochlear implants, and artificial limbs scratch-resistant lenses for glasses, are all works that have contributions from NASA. Anyways, radiation was a fun topic today, but stay tuned for Martian Medicine 102, coming soon when we will talk about the other health risks of going to Mars.____________________Conclusion: Now we conclude episode number 134 “Martian Medicine 101.” As you can see, family medicine is unlimited, in the future you may be working on Mars as a family doctor. An inquisitive future doctor, Wendy Collins, explained that radiation is one of the major risks of long space flights because besides cancer, radiation may also cause cardiovascular diseases, immune deficiencies, and respiratory problems. Dr. Arreaza reminded us that radiation does not affect everyone the same way and even though astronauts are screened extensively, at this point it is difficult to determine with precision who will be a perfect fit for space flights. Stay tuned for Martian Medicine 102.This week we thank Hector Arreaza and Wendy Collins. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________Links:Patel, Z.S., Brunstetter, T.J., Tarver, W.J. et al. Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars. npj Microgravity 6, 33 (2020). https://doi.org/10.1038/s41526-020-00124-6Royalty-free music used for this episode: Space Orbit by Scott Holmes, downloaded on July 20, 2022 from https://freemusicarchive.org/music/Scott_Holmes/. 

In this episode, we take an inside look at how Dr. Lehnhardt and his team of engineers are preparing the next generation of astronauts against the health hazards of space travel to the red planet. Dr. Lehnhardt shares his journey from his home of origin in Canada as an emergency medicine physician to spearheading the Human Research Project efforts in the Lonestar state, as a senior faculty at the Center for Space Medicine, and as an Element Scientist in NASA's Exploration Medical Capability arm of the Human Research Program at the Johnson Space Center.

This Tuesday, Amazon founder and the richest man on the planet, Jeff Bezos, entered space for the first time. This was the virgin flight for Blue Origin, the space travel company that Bezos founded, and lasted 10 minutes and 10 seconds. Bezos's trip came just days after billionaire Richard Branson reached the edge of space on board his Virgin Galactic rocket plane. The company currently has more than 600 reservations, a trip that costs his commercial passengers, $250,000 apiece. The company hopes to launch to the public next year. While the White House called Bezos's flight a “moment of American exceptionalism,” others have been less than thrilled to see the wealthiest in the country head into the heavens.  “Watching the coverage of the billionaires going to space and the notion that it may pave the way for all of us to go in the future. Can I just ask why they think everyone would want to go to space for 8 minutes? And how is this a good use of millions of $? How bout curing cancer?,” wrote former World Vision head Richard Stearns in a series of tweets. “It is estimated that Bezos spent $5.5 billion to achieve his space flight. That same amount of money could have brought clean water to 110 million people who currently have no access. It could also have given a $4000 raise to every one of Amazon's 1.3mm employees.” After his flight, Bezos thanked “every Amazon employee, and every Amazon customer. Because you guys paid for all this.” Bezos says he funds Blue Origin by selling $1 billion of Amazon stock annually. Mark J. Shelhamer is former chief scientist of NASA's Human Research Program. He is professor of otolaryngology, head and neck surgery, at Johns Hopkins University, where he is also director of the Human Spaceflight Lab. He most recently also became the director and founder of the Bioastronautics@Hopkins initiative. Shelhamer has been involved in human spaceflight research since the 1980s and serves as an adviser to commercial spaceflight federation. Shelhamer joined global media manager Morgan Lee and executive editor Ted Olsen to discuss whether Christians should celebrate billionaires in space, why not everyone was a fan of spaceflight when it first took off, and and how working in this industry has affected his relationship with God. What is Quick to Listen? Read more Rate Quick to Listen on Apple Podcasts Follow the podcast on Twitter Follow our hosts on Twitter: Morgan Lee and Ted Olsen Read an essay from Mark Shelhamer Music by Sweeps Quick to Listen is produced by Morgan Lee and Matt Linder The transcript is edited by Faith Ndlovu Learn more about your ad choices. Visit megaphone.fm/adchoices

Bill Paloski, former director of the Human Research Program at NASA's Johnson Space Center, explores the idea of artificial gravity within a spacecraft for long-duration missions and explains how it may affect the human body from what we have learned through Earth-based studies. HWHAP Episode 188.

Bill Paloski, former director of the Human Research Program at NASA's Johnson Space Center, explores the idea of artificial gravity within a spacecraft for long-duration missions and explains how it may affect the human body from what we have learned through Earth-based studies. HWHAP Episode 188.

Bill Paloski, former director of the Human Research Program at NASA’s Johnson Space Center, explores the idea of artificial gravity within a spacecraft for long-duration missions and explains how it may affect the human body from what we have learned through Earth-based studies. HWHAP Episode 188.

Bill Paloski, former director of the Human Research Program at NASA’s Johnson Space Center, explores the idea of artificial gravity within a spacecraft for long-duration missions and explains how it may affect the human body from what we have learned through Earth-based studies. HWHAP Episode 188.

Dr. Tom Williams, element scientist for human factors and behavioral performance in the Human Research Program at NASA's Johnson Space Center, details a reminder called CONNECT and how it not only benefits astronauts in space but those on terra firma here on Earth. HWHAP Episode 162.

Dr. Tom Williams, element scientist for human factors and behavioral performance in the Human Research Program at NASA's Johnson Space Center, details a reminder called CONNECT and how it not only benefits astronauts in space but those on terra firma here on Earth. HWHAP Episode 162.

Dr. Tom Williams, element scientist for human factors and behavioral performance in the Human Research Program at NASA’s Johnson Space Center, details a reminder called CONNECT and how it not only benefits astronauts in space but those on terra firma here on Earth. HWHAP Episode 162.

Dr. Tom Williams, element scientist for human factors and behavioral performance in the Human Research Program at NASA’s Johnson Space Center, details a reminder called CONNECT and how it not only benefits astronauts in space but those on terra firma here on Earth. HWHAP Episode 162.

Today on The Evolved Caveman, a sobering yet incredibly important topic, that of suicide. This conversation may be triggering for some listeners. If you are actively considering suicide, please call the National Suicide Prevention Lifeline at 1-800-273-8255. Dr. Thomas Joiner is a world renowned expert on suicide and is the author of “Lonely at the Top: The High Cost of Men’s Success” and “Why People Die by Suicide.” He has spent much of his career trying to find out why people die of suicide. The desire for death is comprised of two psychological states. One is a perception of being a burden to others, and the other is a feeling of not feeling connected to a family or a relationship. Combined with a third aspect — an “acquired capacity” for suicide (a fearlessness for death)— the risk for suicide is increased. Today, an important talk on depression and suicidality, particularly in light of a recent CDC report that came out August 14 of 2020 on a 40% surge in mental health challenges due to COVID; a conversation about the best ways to help men avoid lives of quiet desperation – feeling less than, isolation from others and addiction – through positive changes individually, in our culture and support services. If you are a man living with these challenges, or if you are worried about a man in your life, you must listen to this conversation. Dr. Joiner is The Robert O. Lawton Distinguished Professor in the Department of Psychology at Florida State University (FSU), Tallahassee, Florida. Dr. Joiner’s work is on the psychology, neurobiology, and treatment of suicidal behavior and related conditions. Author of over 600 peer-reviewed publications, Dr. Joiner was awarded the Guggenheim Fellowship and the Rockefeller Foundation’s Bellagio Residency Fellowship. The Lawton Professorship, which Dr. Joiner received in 2010, is FSU’s single highest honor. He was a consultant to NASA’s Human Research Program, and is the Director, with Pete Gutierrez, Ph.D., of the DoD-funded Military Suicide Research Consortium, a ten-year $70 million project. Largely in connection with Why People Die by Suicide, he has made numerous radio, print, and television appearances, including articles in The Wall Street Journal, a radio interview on NPR’s Talk of the Nation, and two appearances on the Dr. Phil Show. He runs a part-time clinical and consulting practice specializing in suicidal behavior. Thomas Joiner’s Books: • Why People Die by Suicide • Myths about Suicide • Lonely at the Top: The High Cost of Men’s Success • The Perversion of Virtue: Understanding Murder-Suicide Check us out on Google Play and give us a Like and Subscribe! https://play.google.com/music/listen#/ps/Imo4l6pgrbmeklxvec6pgwzxnz4 If you like what you've heard, support us by subscribing, leaving reviews on Apple podcasts. Every review helps to get the message out! Please share the podcast with friends and colleagues. Follow Dr. John Schinnerer on | Instagram | Instagram.com/@TheEvolvedCaveman | Facebook | Facebook.com/Anger.Management.Expert | Twitter | Twitter.com/@JohnSchin | LinkedIn | Linkedin.com/in/DrJohnSchinnerer Or join the email list by visiting: GuideToSelf.com Please visit our YouTube channel and remember to Like & Subscribe! https://www.youtube.com/user/jschinnerer Editing/Mixing/Mastering by: Brian Donat of B/Line Studios www.BLineStudios.com Music by: Zak Gay http://otonamimusic.com/

Kris Lehnhardt is a medical doctor working at NASA JSC in the Human Research Program. Kris leads the science side of the XMC team, which develops medical systems that enable future human exploration beyond low Earth orbit (LEO). In our discussion, we cover the fundamentals of designing human-rated spacecraft, how NASA has changed its approach over the years, and what we need to do to keep humans healthy when going beyond LEO for long durations. Timestamps: 00:00 Introductions 01:34 Education & SEDS 11:15 Space Medicine and Designing Spacecraft for Humans

The Space Policy Show is pleased to hear from Dr. Kris Lehnhardt, from NASA's Human Research Program, and Aerospace's own Kara Cunzeman and Dr. Angie Bukley. This episode discusses the elements that make human space exploration uniquely challenging. Why is space so hard on humans? What would it take to sustain human life in space?

Jason Weeks and Steve Platts discuss the ways NASA is collecting radiation data to better understand the risks and possible mitigation strategies for humans traveling through deep space. This is the last in a six part series on NASA's Human Research Program. HWHAP Episode 128.

Jason Weeks and Steve Platts discuss the ways NASA is collecting radiation data to better understand the risks and possible mitigation strategies for humans traveling through deep space. This is the last in a six part series on NASA's Human Research Program. HWHAP Episode 128.

Jason Weeks and Steve Platts discuss the ways NASA is collecting radiation data to better understand the risks and possible mitigation strategies for humans traveling through deep space. This is the last in a six part series on NASA’s Human Research Program. HWHAP Episode 128.

Brandon Vessey and Cherie Oubre discuss how they integrate and manage all the human research work in areas such as human performance, health, and radiation for research on the International Space Station, on Earth, and for future space exploration. This is part five of a six part series on NASA's Human Research Program. HWHAP episode 127.

Brandon Vessey and Cherie Oubre discuss how they integrate and manage all the human research work in areas such as human performance, health, and radiation for research on the International Space Station, on Earth, and for future space exploration. This is part five of a six part series on NASA's Human Research Program. HWHAP episode 127.

Brandon Vessey and Cherie Oubre discuss how they integrate and manage all the human research work in areas such as human performance, health, and radiation for research on the International Space Station, on Earth, and for future space exploration. This is part five of a six part series on NASA’s Human Research Program. HWHAP episode 127.

Laura Bollweg and Peter Norsk detail the effects that the microgravity environment has on human health, what we're doing to counteract some of these effects, and the studies taking place to better understand how the Moon and Mars may have different impacts. This is part four of a six part series on NASA's Human Research Program. HWHAP Episode 126.

Laura Bollweg and Peter Norsk detail the effects that the microgravity environment has on human health, what we're doing to counteract some of these effects, and the studies taking place to better understand how the Moon and Mars may have different impacts. This is part four of a six part series on NASA's Human Research Program. HWHAP Episode 126.

Laura Bollweg and Peter Norsk detail the effects that the microgravity environment has on human health, what we’re doing to counteract some of these effects, and the studies taking place to better understand how the Moon and Mars may have different impacts. This is part four of a six part series on NASA’s Human Research Program. HWHAP Episode 126.

Nancy Fleming and Kris Lehnhardt describe the challenges of providing the necessary medical capabilities to astronauts traveling deeper into space. This is part three of a six part series on NASA's Human Research Program. HWHAP Episode 125.

Nancy Fleming and Kris Lehnhardt describe the challenges of providing the necessary medical capabilities to astronauts traveling deeper into space. This is part three of a six part series on NASA's Human Research Program. HWHAP Episode 125.

Nancy Fleming and Kris Lehnhardt describe the challenges of providing the necessary medical capabilities to astronauts traveling deeper into space. This is part three of a six part series on NASA’s Human Research Program. HWHAP Episode 125.

Aaron Allcorn and Tom Williams discuss NASA's efforts to understand the optimal spaceflight environment that maximizes human performance. This is part two of a six part series on NASA's Human Research Program. HWHAP Episode 124.

Aaron Allcorn and Tom Williams discuss NASA's efforts to understand the optimal spaceflight environment that maximizes human performance. This is part two of a six part series on NASA's Human Research Program. HWHAP Episode 124.

Aaron Allcorn and Tom Williams discuss NASA’s efforts to understand the optimal spaceflight environment that maximizes human performance. This is part two of a six part series on NASA’s Human Research Program. HWHAP Episode 124.

Dr. Jenn Fogarty gives an overview of the Human Research Program at NASA's Johnson Space Center. This is the first in a series of six episodes that dive deep into the work being done to understand what exactly happens to the human body in space. HWHAP Episode 123.

Dr. Jenn Fogarty gives an overview of the Human Research Program at NASA's Johnson Space Center. This is the first in a series of six episodes that dive deep into the work being done to understand what exactly happens to the human body in space. HWHAP Episode 123.

Dr. Jenn Fogarty gives an overview of the Human Research Program at NASA's Johnson Space Center. This is the first in a series of six episodes that dive deep into the work being done to understand what exactly happens to the human body in space. HWHAP Episode 123.

The rigours and challenges of spaceflight are remarkably similar to the physical stress cancer patients experiment during chemotherapy and other treatments, according to researchers.For that reason, the researchers suggest that the countermeasures program used by astronauts before, during and after spaceflight to maintain their health could be developed and applied for cancer patients to help them recover after treatment.The details were published in a commentary written by researchers from Memorial Sloan Kettering Cancer Center and NASA on Thursday in the journal Cell. The work was supported by the National Cancer Institute."It was surprising when we looked at similarities between astronauts during spaceflight and cancer patients during treatment. Both have a decrease in muscle mass, and they have bone demineralization and changes in heart function," said Jessica Scott, senior author and an exercise physiology researcher at the Memorial Sloan Kettering Cancer Center's Exercise Oncology Service. "Astronauts may get something called space fog, where they have trouble focusing or get a little forgetful. That's very similar to what some cancer patients experience, which is called chemo brain."But astronauts and cancer patients are advised in a completely different way from each other, despite the similar issues they face. The authors of the commentary looked at the countermeasures program created by NASA to see how it might be applied to cancer patients.For 58 years, NASA has been sending humans into space, with flights ranging from 15 minutes in duration in 1961 to nearly a year on the International Space Station for current astronauts.The quest for countermeasures to help humans remain stable and healthy in space began early. They didn't know what effect zero gravity might have on the body or specific organs. And they were mainly concerned with cardiac injury, so multiple assessments were used to monitor that activity before, during and after flight, according to the commentary.NASA's concerns were valid. Apollo astronaut James Irwin had an undetected coronary heart disease and 21 months after returning to Earth, he suffered an acute myocardial infarction, the authors wrote.Initially, the Project Mercury astronauts, announced in 1959, had to run each day for a month before their spaceflight. Gemini astronauts exercised before their missions and during spaceflight as well, using bungee cords. By the time space station missions began in 2001, NASA had astronauts performing a combination of aerobic exercise and strength training during their 91- to 215-day missions.Now, in the months prior to their launch, astronauts work with specialists to create a strength, condition and rehab program to create a baseline before flight. They continue the program using equipment on the station. When they return, the astronauts are monitored as they exercise to be sure that their fitness returns to the baseline level established before spaceflight.After more than 50 years of human spaceflight, researchers know some of the risks posed to the human body by being in zero gravity. Astronauts have to deal with a stressful environment, noise, isolation, disrupted circadian rhythm, radiation exposure and a headward fluid shift that happens when floating as opposed standing on solid ground.Over time, astronauts staying for six months or more on the station can experience the weakening and loss of bone and muscle atrophy. Astronauts also experience blood volume loss, weakened immune systems and cardiovascular deconditioning since floating takes little effort and the heart doesn't have to work as hard to pump blood, according to NASA's Human Research Program.The countermeasures were developed to mitigate these risks. But as the authors of the commentary point out, "Cancer is the only major chronic disease condition in which a comparable countermeasures program is not an aspect of standard management."In contrast with astronauts who are...

NASA Human Research Program Director Bill Paloski discusses methods and technologies to support safe, productive human space travel to the Moon and Mars.

NASA Human Research Program Director Bill Paloski discusses methods and technologies to support safe, productive human space travel to the Moon and Mars.

NASA Human Research Program Director Bill Paloski discusses methods and technologies to support safe, productive human space travel to the Moon and Mars.

The Human Research Program is NASA's comprehensive effort to enable safe and productive travel for people in space. Now retired identical twin astronauts Scott and Mark Kelly took part in a year long mission to closely compare changes in their bodies. Scott spent more than 300 days aboard the ISS, while Mark remained on Earth. Both submitted to regular checks of their immune systems, genetics, bone formation, gut bacteria, the effects of vaccines, radiation and biochemical changes. The information recorded will be used for years to come to understand how to make a return journey to Mars survivable.

Dr. John Charles spent nearly 33 years at NASA—most recently as Chief Scientist of the Human Research Program—working on human spaceflight through Shuttle, Mir, ISS, and beyond. He lead missions such as STS-95 (John Glenn’s Shuttle flight), STS-107, and the Twins Study with Scott and Mark Kelly. He retired from NASA in February 2018 and is now the Scientist in Resident at Space Center Houston. We talk about his career, the human spaceflight issues he worked and solved in his time at NASA, and the things that need to be solved for the exploration of the Moon, Mars, and beyond. This episode of Main Engine Cut Off is brought to you by 39 executive producers—Kris, Pat, Matt, Jorge, Brad, Ryan, Jamison, Nadim, Peter, Donald, Lee, Jasper, Chris, Warren, Bob, Russell, John, Moritz, Joel, Jan, David, Grant, Mike, David, Mints, Joonas, Robb, Tim Dodd the Everyday Astronaut, Frank, Rui, Julian, Lars, Heather, and six anonymous—and 238 other supporters on Patreon. AstroCryptoTriviology, John’s Blog About John John Charles (@csm014) | Twitter Human Research Program | NASA Email your thoughts, comments, and questions to anthony@mainenginecutoff.com Follow @WeHaveMECO Listen to MECO Headlines Join the Off-Nominal Discord Subscribe on Apple Podcasts, Overcast, Pocket Casts, Spotify, Google Play, Stitcher, TuneIn or elsewhere Subscribe to the Main Engine Cut Off Newsletter Buy shirts and Rocket Socks from the Main Engine Cut Off Shop Support Main Engine Cut Off on Patreon Music by Max Justus

In this episode, we continue our interview with John Charles on a number of MOL topics, including tying up the discussion on MOL artwork from part 1, the declassification of MOL materials, and the legacy of MOL—including some time devoted to paying respects to Robert Lawrence, a so-called “Hidden Figure” from the MOL Air Force pilot corps.Check out John's page with information on MOL, including articles he has written and a section devoted to MOL art: http://www.astrocryptotriviology.com/mol-artJohn also makes mention of author Megan Prelinger… check out her book entitled, “Another Science Fiction: Advertising the Space Race 1957-1962.”This is Part 2 of our Manned Orbiting Laboratory interview.Note: apologies for some noise distortion with Emily Carney's voice; our VOIP system for recording podcasts is, at best, imperfect! We apologize in advance for the quality of portions of the recording.++++++++++++++++John Charles was a long-time NASA life scientist and science manager with a life-long interest in spaceflight history. He retired from NASA on February 22, 2018, after nearly thirty-three years in a career that started as a cardiovascular investigator on Space Shuttle flights, spanned Mir missions and the Shuttle flight of John Glenn, included overseeing the joint US/Russian one-year mission on ISS and the Twins Study, and peaked as the Chief Scientist of NASA's Human Research Program, guiding NASA biomedical research on the International Space Station in preparation for sending astronauts to Mars.John is now the first scientist-in-residence at Space Center Houston, the official visitors center of the Johnson Space Center, and an emeritus employee of the Johnson Space Center mentoring younger scientists. He is an Adjunct Professor of Kinesiology at Texas A&M University. He and his wife Kathy own ACT4space, LLC, a private outreach, education, research, and consulting business.In addition, John is applying his decades of experience in space biomedical research and oversight to understanding the human health and performance aspects of the Manned Orbiting Laboratory, a cancelled program by the U.S. Air Force and the National Reconnaissance Office to put military astronauts into low Earth orbit to conduct detailed observations of Soviet and Chinese capabilities during the Cold War.

In this episode, we'll learn how John Charles became interested in the Manned Orbiting Laboratory in the first place, and then we'll spend some time discussing the art of MOL.Check out John's page with information on MOL, including articles he has written and a section devoted to MOL art: http://www.astrocryptotriviology.com/mol-artThis is Part 1 of our Manned Orbiting Laboratory interview.++++++++++++++++John Charles was a long-time NASA life scientist and science manager with a life-long interest in spaceflight history. He retired from NASA on February 22, 2018, after nearly thirty-three years in a career that started as a cardiovascular investigator on Space Shuttle flights, spanned Mir missions and the Shuttle flight of John Glenn, included overseeing the joint US/Russian one-year mission on ISS and the Twins Study, and peaked as the Chief Scientist of NASA's Human Research Program, guiding NASA biomedical research on the International Space Station in preparation for sending astronauts to Mars.John is now the first scientist-in-residence at Space Center Houston, the official visitors center of the Johnson Space Center, and an emeritus employee of the Johnson Space Center mentoring younger scientists. He is an Adjunct Professor of Kinesiology at Texas A&M University. He and his wife Kathy own ACT4space, LLC, a private outreach, education, research, and consulting business.In addition, John is applying his decades of experience in space biomedical research and oversight to understanding the human health and performance aspects of the Manned Orbiting Laboratory, a cancelled program by the U.S. Air Force and the National Reconnaissance Office to put military astronauts into low Earth orbit to conduct detailed observations of Soviet and Chinese capabilities during the Cold War.

In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 2 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences.

In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 1 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired from NASA in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences

In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 3 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired from NASA in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences.

I have a drink with the Deputy Chief Scientist for the Human Research Program at Nasa....Yeah. You read that right. The Deputy Chief Scientist for the Human Research Program, Steve Platts, who also happens to be a big Whiskey Guy. I try and figure out what exactly that means...I'm 90% sure he's trying to find a cure for the impending Zombie Apocalypse...or aliens, probably aliens.

Dr. John Charles, Chief Scientist of the Human Research Program at the NASA Johnson Space Center, talks about what happens to the human body in space. NASA astronaut Shane Kimbrough gives a first hand account of landing from space. HWHAP Episode 3.

Dr. John Charles, Chief Scientist of the Human Research Program at the NASA Johnson Space Center, talks about what happens to the human body in space. NASA astronaut Shane Kimbrough gives a first hand account of landing from space. HWHAP Episode 3.

Dr. John Charles, Chief Scientist of the Human Research Program at the NASA Johnson Space Center, talks about what happens to the human body in space. NASA astronaut Shane Kimbrough gives a first hand account of landing from space. HWHAP Episode 3.

(17 May 2009) — Astronaut Mike Massimino peers through a window on the aft flight deck of the Earth-orbiting Space Shuttle Atlantis during the mission’s fourth session of extravehicular activity (EVA) to refurbish and upgrade the Hubble Space Telescope. Going to Mars is hot right now, just ask Matt Damon. But would you go if you knew your bones would turn into something called “pee brittle”? Former astronaut Michael Massimino reveals the uncomfortable side of liftoff. And Dr. Jennifer Fogarty from NASA’s Human Research Program elaborates on the physical challenges humans face with longterm weightlessness.

What will it take to send people to Mars safely, and bring them home again? StarTalk All-Stars host Astro Mike Massimino and co-host Maeve Higgins find out from John Charles, the Chief Scientist at NASA's Human Research Program.

What will it take to send people to Mars safely, and bring them home again? StarTalk All-Stars host Astro Mike Massimino and co-host Maeve Higgins find out from John Charles, the Chief Scientist at NASA’s Human Research Program.

What will it take to send people to Mars safely, and bring them home again? StarTalk All-Stars host Astro Mike Massimino and co-host Maeve Higgins find out from John Charles, the Chief Scientist at NASA’s Human Research Program.

Dr. John Charles (@csm014 on twitter) returns with host Craig Price to talk the reality of the movie The Martian. As we learned from his past episode, Dr. Charles works at NASA’s Human Research Program learning how to protect the delicate human body from the harsh reality of space travel. But what happens once we get there? The Matt Damon movie The Martian covers this and then some, speculating on how one man could survive on Mars for 500 days. It's a great movie but how much of it is feasible? Craig and Dr. Charles discuss the power of duct tape, the magic of potatoes, how fine the dust and dirt on Mars actually is and how windy is it there. A  massive SPOILER ALERT is needed so if you haven't seen the movie, go now and then come right back here to listen on what's true and what is artistic license. You can read Dr. Charles’ blog  astrocryptotriviology.blogspot.com, an occasional blog covering obscure but interesting minor aspects of spaceflight, and what they tell us about the grand human adventure that is space exploration. Also, Craig's annual charity calendar supporting Orangutan Outreach is now available. Buy one (or a dozen) today!

Dr. John Charles (@csm014 on twitter) joins host Craig Price to talk the reality of space travel. Being a super nerd and getting the chance to visit NASA earlier in the year, Craig was super geeked to be able to talk to someone actually helping NASA get people into space and beyond safely. Dr. Charles works at NASA's Human Research Program learning how to protect the delicate human body from the harsh reality of space travel. The two discuss why squishing internal organs isn't something you want to do first thing on a mission, why bone density decreases the longer you are in zero G and why cosmic radiation will be the biggest hurdle for space travelers. They also talk about artificial gravity's progress (or lack there of), what space travel will look like in 100 years and how deficient Craig's vocabulary is compared to a dual doctorate. You can read Dr. Charles' blog  astrocryptotriviology.blogspot.com, an occasional blog covering obscure but interesting minor aspects of spaceflight, and what they tell us about the grand human adventure that is space exploration.