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Next stop - the moon! Jeremy Hansen stops by our studio to chat about how he's prepping to be the first Canadian to go to the moon.Plus:Santa's reindeer may be losing their antlers –– and climate change could be the culpritReindeer are the only animal in the deer family where the females also grow antlers, and they typically have a full rack over the wintertime and drop them in June when they give birth. University of Guelph PhD student Allegra Love was monitoring reindeer on Fogo Island in Newfoundland, when she made a surprising discovery that female reindeer are losing and growing their antlers much earlier than usual. This can put more stress on the animal during a crucial part of their pregnancy, and the researchers think this could eventually lead to the reindeer losing their antlers altogether. The work was published in the journal Ecosphere.Pterosaur brains reveal clues about why these mighty fliers took to the skiesFlight has only evolved among vertebrates three times — in bats, birds, and first in pterosaurs. How pterosaurs first took to the skies was always a mystery to scientists, until the discovery of a fossilized 230-million year old pterosaur relative in Brazil. An international team, including Ohio University professor Lawrence Witmer, used an MRI for detailed analysis of the fossilized skull, to pinpoint the miniscule brain changes that happened as the animal developed the capacity to fly. The research was published in the journal Current Biology.Scientists are using AI to find life in 3 billion year old rocksEarth's earliest signs of life are often incredibly difficult to detect. An international team of researchers have developed a new tool that uses AI to find “whispers” of life locked inside ancient rocks. Using this tool, the researchers, including astrobiologist Michael Wong from Carnegie Science, were able to detect fresh chemical evidence of life in rocks that are 3.3 billion years old. This tool can not only be used to explore the origins of life here on Earth, but also on Mars and other planetary bodies. The work was published in the journal PNAS.
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, Vanessa sits down with Dr. Howard, the lead author of a brand-new PNAS study that is challenging one of the most widely accepted ideas in human metabolism. For years, many scientists believed that our bodies operate within a fixed daily calorie "budget," and that after a certain point, increasing activity doesn't increase total calorie burn. But Dr. Howard's new research suggests the story may be far more dynamic — and far more empowering — than we ever realized. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. This conversation explores what this new evidence could mean for: How we think about calorie burn Why activity matters (in ways we didn't fully understand before) The role of fueling, recovery, and energy balance What actually drives fat loss and body recomposition How to train smarter, not harder Mentioned in this episode: Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation — published in Proceedings of the National Academy of Sciences (PNAS). Read the full study here → PNAS DOI 10.1073/pnas.2519626122 NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 20% off on the Tone Device breath ketone analyzer or the Tone LUX Crystal Red Light Therapy Mask or the at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Die Themen in den Wissensnachrichten: +++ Unser Gehirn ist erst mit Anfang 30 auf dem Entwicklungs-Höhepunkt +++ Bettwanzen als Beweismittel +++ Warum wir im Bett bleiben wollen, wenn wir krank sind +++**********Weiterführende Quellen zu dieser Folge:Topological turning points across the human lifespan, Nature Communications, 25.11.2025Protocol for tropical bed bug use as forensic tools, Forensic Science International, Oktober 2024Sequence organization of mother–infant interactions in chimpanzees (Pan troglodytes schweinfurthii) in the wild, Proceedings of the Royal Society B, 26.11.2025IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness, Cell, 25.11.2025Mating system of free-ranging domestic dogs and its consequences for dog evolution, PNAS, 24.11.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Die Themen in den Wissensnachrichten: +++ Knochen belegen frühe Koexistenz von Mensch und Wolf +++ Social Media-Detox hilft schnell +++ Neue Korallenart wächst auf Manganknollen +++**********Weiterführende Quellen zu dieser Folge:Gray wolves in an anthropogenic context on a small island in prehistoric Scandinavia, PNAS, 24.11. 2025Social Media Detox and Youth Mental Health, JAMA, 24.11. 2025Hidden gems of the abyss: first species of azooxanthellate scleractinian coral (Scleractinia: Deltocyathidae) attached to polymetallic nodules in the eastern Pacific Ocean, Zoological Journal of the Linnean Society, November 2025The Moon-forming impactor Theia originated from the inner Solar System, Science, 20.11. 2025Shared and language-specific phonological processing in the human temporal lobe. Nature, 19.11.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Air quality and pet health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Stephen Jarvis explores the health impacts of poor air quality on pets. In this episode, we cover: •[00:00] Introduction •[00:51] Environmental economist Stephen Jarvis explains how he became interested in the effects of air quality on pets. •[01:59] He talks about the similarities in exposure between humans and pets, and introduces the veterinary dataset used in the study. •[03:30] Jarvis explains the results of the study and the potential physiological effects of poor air quality. •[05:40] He talks about the implications of reducing air pollution for petcare and the takeaway messages of the study. •[08:17] Jarvis explains the caveats and limitations of the study. •[09:14] Conclusion. About Our Guest: Stephen Jarvis Assistant professor London School of Economics View related content here: https://www.pnas.org/doi/10.1073/pnas.2504553122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Welcome to The Sleep Edit, the podcast that helps tired kids and parents sleep better. Each week, Dr. Craig Canapari and sleep consultant Arielle Greenleaf break down evidence-based strategies you can actually use. Why are nap transitions so confusing—and why do they so often derail nights? In Part 2 of our napping series, Craig and Arielle dig into the real-world challenges families face when moving from 3→2 naps, 2→1 nap, and eventually dropping naps entirely. Using concrete examples, sleep-need math, and practical troubleshooting, this episode explains exactly what to look for and how to navigate every transition with less stress. You'll learn • How to know when it's time to drop a nap • The signs of a nap transition vs. a temporary “nap strike” • Why total 24-hour sleep matters more than wake-window charts • What typical daytime sleep looks like for infants and toddlers • The sleep math behind transitions (high vs. low sleep-need kids) • How daycare schedules can derail naps—and what parents can control • Strategies for capping naps, shifting schedules, and preventing bedtime battles • When early morning awakenings actually signal too much daytime sleep Chapters 00:00:01 — Welcome & Episode Setup 00:01:07 — The 3→2 Nap Transition: When It Starts 00:02:48 — Biology of Sleep Drive & Late Naps 00:03:43 — Why Late Bedtimes Are So Common Now 00:04:59 — How Total Sleep Needs Shape Nap Schedules 00:06:32 — Wake Windows vs. Real Sleep Need 00:07:52 — Consolidated Naps & Nap Length Targets 00:09:41 — How to Use the Third Nap as a Bridge 00:11:06 — Example: Designing a 13.5-hour Sleep Day 00:12:59 — Signs It's Time to Drop From 3→2 Naps 00:14:45 — Why Transitions Are Messy (and Normal) 00:15:56 — The 2→1 Nap Transition: Age & Signs 00:17:46 — Developmental Milestones That Disrupt Naps 00:19:06 — Case Example: Drew (13 Months) 00:20:57 — How to Start the 2→1 Transition Step-by-Step 00:22:54 — Shifting Nap Timing & Early Bedtime Strategy 00:23:56 — Tracking Sleep: Apps vs. Diaries 00:24:53 — Why Smart Monitors Often Mislead Parents 00:26:50 — When Nights Get Worse Because of Nap Issues 00:27:59 — The 1→0 Transition: What Truly Signals Readiness 00:29:18 — Daycare Nap Challenges & Parent Options 00:31:56 — Capping Naps to Protect Nighttime Sleep 00:33:30 — Nap Strikes vs. True Transitions 00:36:06 — Early Morning Awakenings & Too Much Day Sleep 00:38:30 — Final Thoughts & The Greenleaf Windows Links Napping spectacular episode 1 CIO episode of the Sleep Edit Dr. Canapari's article on Le Pause Sleep training Period of purple crying Dr. Canapari's article on napping Dr. Canapari's article on sleep needs in children Dr. Canapari articles on the science of why children stop napping Arielle's website References Paruthi, S., Brooks, L. J., D'Ambrosio, C., Hall, W. A., Kotagal, S., Lloyd, R. M., Malow, B. A., Maski, K., Nichols, C., Quan, S. F., Rosen, C. L., Troester, M. M., & Wise, M. S. (2016). Consensus statement of the American Academy of Sleep Medicine on the recommended amount of sleep for healthy children: methodology and discussion. Journal of Clinical Sleep Medicine, 12(11), 1549–1561. https://doi.org/10.5664/jcsm.6288 Spencer, R. M. C., & Riggins, T. (2022). Contributions of memory and brain development to the bioregulation of naps and nap transitions in early childhood. PNAS, 119(11), e2114326119. https://doi.org/10.1073/pnas.2114326119 Staton, S., et al. (2020). Many naps, one nap, none: A systematic review and meta-analysis of napping patterns in children 0–12 years. Sleep Medicine Reviews, 50, 101247. https://doi.org/10.1016/j.smrv.2019.101247 Galland, B. C., Taylor, B. J., Elder, D. E., & Herbison, P. (2012). Normal sleep patterns in infants and children: A systematic review of observational studies. Sleep Medicine Reviews, 16(3), 213–222. https://doi.org/10.1016/j.smrv.2011.06.001 Horváth, K. (2018). Spotlight on daytime napping during early childhood. Frontiers in Psychology, 9, 1238. https://doi.org/10.3389/fpsyg.2018.01238 Wolke, D., Bilgin, A., & Samara, M. (2017). Systematic review and meta-analysis: Fussing and crying durations and prevalence of colic in infants. The Journal of Pediatrics, 185, 55–61.e4. https://doi.org/10.1016/j.jpeds.2017.02.020 Lavner, J. A., et al. (2023). Sleep SAAF randomized clinical trial. JAMA Network Open, 6(3), e236276. https://doi.org/10.1001/jamanetworkopen.2023.6276 Paul, I. M., et al. (2016). INSIGHT Responsive Parenting Intervention and Infant Sleep. Pediatrics, 138(1), e20160762. https://doi.org/10.1542/peds.2016-0762
Responding to @TimcastIRL and @The_Crucible after they aired a segment on my plural family, linked below.Should Polygamist Families be Welcome at Church? - https://richtidwell.com/should-polygamist-families-be-welcome-at-church/A Letter to the Anglican Church: https://bit.ly/PolygynyLetterOn Plural Marriage: https://richtidwell.com/on-plural-marriage/The Mia & Heis Saga: https://richtidwell.com/mia-and-heis/St. Augustine, On The Good of Marriage: https://www.newadvent.org/fathers/1309.htm"Andrew Wilson Slams Protestant Pastor For Saying Polygamy Is Biblical" - https://www.youtube.com/watch?v=9CPYbTjcUhgSTUDIES- Birthrates: https://x.com/richtidwell/status/1989109694481170715- London School of Economics and Political Science: https://www.lse.ac.uk/news/new-study-challenges-claim-polygyny-drives-men-to-civil-war- PNAS polygamy study: https://www.pnas.org/doi/10.1073/pnas.2508091122- Females outnumber men: https://www.medicaldaily.com/female-population-has-always-outnumbered-males-historically-according-our-genes-304428- More Christian women in US then men: https://www.pewresearch.org/religious-landscape-study/gender-composition/woman/- More women in the Church than men: https://www.ncls.org.au/articles/why-are-women-more-religious-than-men/
A giant virus associated with oyster aquaculture mortality Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Curtis Suttle and Kevin Xu Zhong explain how a previously unidentified virus may be connected to mass die-offs of farmed Pacific oysters. In this episode, we cover: • [00:00] Introduction • [01:03] Environmental virologist Curtis Suttle introduces the importance of the Pacific oyster to aquaculture. • [01:42] Suttle describes mass mortality events, including one he witnessed. • [02:42] Environmental microbiologist Kevin Xu Zhong talks about the methods used to identify the Pacific Oyster Nidovirus 1. • [03:53] Zhong describes the notable features of the nidovirus. • [05:19] Zhong and Suttle explain how the nidovirus merits designation of a nidovirus family. • [06:25] Suttle explores the takeaways for oyster farmers and regulators. • [08:15] He lists the caveats and limitations of the study. • [09:40] Conclusion. About Our Guests: Kevin Xu Zhong Research Associate University of British Columbia Curtis Suttle Professor University of British Columbia View related content here: https://www.pnas.org/doi/10.1073/pnas.2426923122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator James D. Watson dies (NY Times) Russian translation of TWiV 1024 (Medium) Canada's new budget aims to lure US researchers (Science) Bird flu surging and spreading while US agencies are asleep (npr) US slashed WHO budget, now flu surveillance is suffering globally (npr) HPV sequences in papillomas and cervical cancers (PNAS) zur Hausen Nobel Prize 2008 (Nobel) Vincent interviews zur Hausen (YouTube) Influenza virus infection, shedding, and disease in humans (J Virol) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Pandemic board game Rich – Whiskey Fungus Fed by Jack Daniel's Encrusts a Tennessee Town Alan – Rats can snatch bats out of the air and eat them Vincent – 7 basic science discoveries that changed the world Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health. Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S– Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
Die Themen in den Wissensnachrichten: +++ Um immer mehr Vitalbereiche der Erde steht es schlecht +++ Widerspruchslösung sorgt nicht automatisch für mehr Organspenden +++ Deutsche Vogelwelt erlebt Wandel +++**********Weiterführende Quellen zu dieser Folge:The 2025 state of the climate report: a planet on the brink, BioScience, 29.10.2025Crowding-out effects of opt-out defaults: Evidence from organ donation policies, PNAS Nexus, 28.10.2025Wie zufrieden sind Ein- und Ausgewanderte? Deutschland im Fokus, BiB-Monitor Wohlbefinden 2025, 29.10.2025Vögel in Deutschland: Bestandssituation 2025, Bundesamt für Naturschutz, 28.10.2025Elevated virus infection of honey bee queens reduces methyl oleate production and destabilizes colony-level social structure, PNAS, 14.10.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Swamp lights and bat sight Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore two spooky mysteries: the source of will-o'-the-wisps and how bats integrate vision with echolocation. In this episode, we cover: •[00:00] Introduction •[00:58] Richard Zare's background and expertise. •[01:26] Richard, have you ever seen will-o'-the-wisps in the wild? •[01:31] What did we already know about will-o'-the-wisps before your study? •[02:42] How could water droplets ignite methane? •[03:24] Tell us about the methods of your study. How did you explore this phenomenon? •[04:17] What are the broader implications of your findings, beyond just will-o'-the-wisps? •[05:20] What are the caveats or the limitations of the study? •[05:40] Laura Stidsholt's background and expertise. •[06:06] Laura, what can you tell us about the species you studied? •[06:25] What instruments did you attach to the bats? •[07:03] How did the bats' echolocation behavior compare in dark versus lit environments? •[08:14] What do the results suggest about the benefits of integrating information from multiple senses while hunting prey? •[08:58] What do the results imply about the potential impact of artificial light on bats? •[09:43] Final thoughts and conclusion. About Our Guests: Richard Zare Marguerite Blake Wilbur Professor of Natural Science Stanford University Laura Stidsholt Assistant Professor Aarhus University View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2521255122 https://www.pnas.org/doi/full/10.1073/pnas.2515087122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Disclaimer: The term woman is frequently used in this episode and Kanwal's book Taking Care of You, to refer to the target audience, although the material discussed applies to anyone with a uterus, cervix, or vagina. We recognize that not all people with these body parts identify as a woman and that not all people who identify as a woman have these body partsKanwal Haq is dedicated to improving health and care for women across the world. With 17+ years of experience working in various healthcare roles and spaces, Kanwal brings dedication, creativity, and humility to keep learning and moving forward. Kanwal founded TCY Women to build better tools, resources, and systems of care to support women's health, across the lifespan. Kanwal completed her B.S. in biology from the University of Missouri, her M.S. in medical anthropology from Boston University, and is working on her PhD in public health at UTHealth. Kanwal is the co-author of “Taking Care of You: The Empowered Woman's Guide to Better Health (Mayo Clinic Press 2022). Kanwal's rural midwestern roots cultivated her passion to make health education and care both accessible and appropriate for every woman.When we look at the research, a clear pattern emerges — women and gender diverse people are too often dismissed, undertreated, and left behind by our healthcare system. The 2024 KFF Women's Health Survey found that one in three women reported being ignored or disbelieved by a healthcare provider, and data from the PNAS (2024) study showed that clinicians consistently rated women's pain as less severe than men's for the same symptoms. Together, these studies tell a sobering truth — gender bias is not anecdotal, it's structural.
Die Themen in den Wissensnachrichten: +++ Technische Lösung bei unheilbarer Augenkrankheit +++ Erstmals Stechmücken in Island entdeckt +++ Bestimmte Gene könnten anfällig machen für Cannabis-Konsum +++**********Weiterführende Quellen zu dieser Folge:Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD, New England Journal of Medicine, 20.10.2025Mosquitoes arrive in Iceland, RUV, 20.10.2025Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals, Molecular Psychiatry, 13.10.2025Invariant HVC size in female canaries singing under testosterone: Unlocking function through neural differentiation, not growth, PNAS, 20.10.2025Oomycetes manipulate plant innate immunity through galacturonide oxidases, Nature Communications, 20.10.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Pendant des décennies, on a cru qu'en multipliant les compliments, on aidait les enfants à s'épanouir. « Tu es le meilleur ! », « Tu es génial ! » — autant de phrases censées nourrir la confiance. Mais selon une recherche conjointe de l'Université d'État de l'Ohio et de l'Université d'Amsterdam, publiée dans la revue PNAS, ces compliments exagérés sont en réalité un piège. Loin de renforcer l'estime de soi, ils peuvent créer des enfants égocentriques, voire manipulateurs, incapables plus tard de relations équilibrées.Tout commence souvent avec de bonnes intentions. Un parent veut encourager son enfant, surtout s'il le sent fragile ou timide. Alors il multiplie les louanges. Mais lorsqu'elles deviennent disproportionnées — quand on félicite non pas l'effort, mais la personne elle-même, en la présentant comme exceptionnelle —, le cerveau de l'enfant apprend une leçon bien différente : pour être aimé, il faut être extraordinaire. Ce n'est plus la curiosité ni la persévérance qui comptent, mais l'image que l'on renvoie.Les chercheurs ont observé que ces enfants finissent par éviter les situations où ils risquent d'échouer. L'échec, pour eux, n'est pas une étape normale de l'apprentissage, mais une menace pour l'identité flatteuse qu'on leur a imposée. Ils préfèrent donc ne pas essayer plutôt que de risquer d'être « démasqués ». Et pour continuer à mériter l'admiration, ils développent des stratégies sociales subtiles : séduire, manipuler, attirer l'attention, parfois rabaisser les autres pour se sentir supérieurs.Peu à peu, l'enfant devient dépendant du regard extérieur. Il mesure sa valeur à travers l'approbation d'autrui. Dans ce processus, une chose s'étiole : l'empathie. S'il se vit comme le centre du monde, les besoins des autres perdent de l'importance. Il ne cherche plus à comprendre, mais à convaincre ; plus à échanger, mais à briller. Ce type d'éducation, en apparence bienveillante, prépare sans le vouloir des adultes narcissiques, fragiles sous leur assurance, et incapables de tisser des liens sincères.Les chercheurs insistent : la clé n'est pas de bannir les compliments, mais de les orienter autrement. Il faut cesser de dire « Tu es incroyable » et apprendre à dire « Tu as bien travaillé ». Féliciter l'effort plutôt que le talent, reconnaître les progrès plutôt que la perfection. C'est ainsi que l'enfant apprend que la valeur ne se joue pas dans le regard des autres, mais dans l'action, la persévérance et la relation à autrui. En somme, c'est en apprenant à échouer qu'on apprend aussi à aimer. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Die Themen in den Wissensnachrichten: +++ Mit Abnehmspritzen gegen Alkoholsucht? +++ Staudamm rettet Teil des Aralsees +++ Warum Seufzen gut tut +++**********Weiterführende Quellen zu dieser Folge:A preliminary study of the physiological and perceptual effects of GLP-1 receptor agonists during alcohol consumption in people with obesity/ Scientific Reports, 15.10.2025Consequences of the Aral Sea restoration for its present physical state: temperature, mixing, and oxygen regime/ Hydrology and Earth System Sciences, 07.08.2025How sighing regulates pulmonary surfactant structure and its role in breathing mechanics/ Science Advances, 24.09.2025Electrostatics facilitate midair host attachment in parasitic jumping nematodes/ PNAS, 14.10.2025Impact of intermittent lead exposure on hominid brain evolution/ Science Advances, 15.10.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Implications of a mutation in modern humans Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Xiangchun Ju and Svante Pääbo explore the evolutionary implications of a mutation that separates modern humans from ancestral hominins. In this episode, we cover: •[00:00] •[01:22] Neurobiologist Xiangchun Ju introduces the enzyme adenylosuccinate lyase, or ADSL, and its role in the synthesis of purine. •[02:09] Evolutionary anthropologist Svante Pääbo talks about the discovery of the A429V mutation, which is present in modern humans but not Neanderthals or Denisovans. •[03:38] Ju and Pääbo talk about the methods to humanize mice in order to study the evolutionary importance of the A429V mutation. •[05:04] They explain the results of the behavioral studies of the humanized mice. •[06:27] Pääbo explores the takeaways from the study. •[08:05] He contextualizes the study alongside other studies of modern human development. •[09:17] Pääbo and Ju list the caveats and limitations of the study. •[10:14] Conclusion. About Our Guests: Xiangchun Ju Postdoctoral scholar Okinawa Institute of Science and Technology Svante Pääbo Director Max Planck Institute for Evolutionary Anthropology View related content here: https://www.pnas.org/doi/10.1073/pnas.2508540122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
I denne episoden tar vi deg med inn i et favoritthack – rebounding, eller trening på minitrampoline! Dette er noe vi gjør hver eneste dag, både hjemme og sammen med deltakerne på Core Balance. Her deler vi hvorfor denne lekne og enkle treningsformen er så effektiv for lymfehelse, energi, humør og avgiftning – og hvordan du kan komme i gang. Gjennom episoden lærer du hvordan lymfen er kroppens rensesystem, hvorfor den trenger bevegelse for å flyte, og hvorfor noen minutters hopping kan gjøre mer for energien din enn en lang løpetur.Dette lærer du i episoden:Hva lymfesystemet er og hvorfor det er helt avgjørende for immunforsvar og energi?Hvordan trampolinetrening kan øke lymfesirkulasjonen opptil tre ganger mer enn vanlig gange?Hva NASA fant ut om hvorfor rebounding er den mest effektive treningsformen for astronauter?Hvordan opp og ned-bevegelsen fungerer som en “indre dusj” som skyller kroppen ren for avfallsstoffer?Hvorfor rebounding er skånsomt for leddene, men likevel styrker muskler, balanse og kondisjon?Den mentale effekten, hvorfor hopping gjør deg lykkeligere, roligere og mer tilstede?Hvordan du kan starte med bare 5–10 minutter om dagen?Hva slags trampoline du bør velge, og hvorfor bungee-strikker er gullstandarden?Hvordan rebounding faktisk kan styrke bekkenbunnen, ikke svekke den?Hvorfor dette er en biohack for alle, uansett alder, form og nivå?Studier: Mukherjee, A. et al., Entrainment of Lymphatic Contraction to Oscillatory Flow, 2019. Kunert, C. et al., Mechanobiological oscillators control lymph flow, PNAS, 2015. Breslin, J.W., Mechanical forces and lymphatic transport, 2014 (review). Bhattacharya, A. et al., Body acceleration distribution and O2 uptake in humans... (NASA report / J Appl Physiol, 1980). Cugusi, L. et al., Effectiveness of a mini-trampoline rebounding exercise program... (2018). Posch, M. et al., Mini-trampoline training program on balance and mobility... (2019). (se tidligere søk / balansestudier).Trampoline: https://www.jumpsport.com/collections/shop-allnorske nettsider, ser bra ut men vi har ikke testet disse:https://ninefit.no/products/newan-40-silent-fitness-mini-trampoline-indoor-rebounder-for-adults-best-urban-cardio-jump-fitness-workout-trainer-covered-bungee-rope-system-max-limit-330-lbs?gad_source=1&gad_campaignid=17181672367https://www.fitshop.no/cardiojump-fitnesstrampoline-premium-cj-ft-100?sku=CJ-FT-125&gad_source=1&gad_campaignid=18598503756Takk til vår samarbeidspartner:Oslo skinlab: Osloskinlab.no: rabattkode: bio60 @osloskinlabBoken vår BIOHACKING, - 21 uker på BESTSELGERLISTEN den finner du her:https://www.ark.no/produkt/boker/hobbyboker-og-fritid/biohacking-9788205611474Nysgjerrig på neste Biohacking Weekend 21 og 22 mars 2026? Mail: christin@kongresspartner.no
In this solo episode, Darin pulls back the curtain on one of the most important parts of his life: he prepares for travel. From the supplements that keep his immune system strong to hydration hacks, adaptogenic elixirs, and EMF protection, this episode is a masterclass in staying grounded and resilient on the road. Travel doesn't have to destroy your health — it can actually elevate it. With a few intentional rituals, smart packing, and awareness, you can turn every trip into an opportunity to deepen your energy, focus, and connection to yourself. What You'll Learn 00:00:00 – Why travel is stressful and how to transform it into an empowering, health-boosting experience 00:01:00 – Darin's supplement protocol: Vitamin D3/K2, probiotics, zinc, vitamin C, and glutathione for immune defense 00:03:00 – The antioxidant power of glutathione and why it's critical for long flights and radiation exposure 00:04:30 – How CBD and terpenes support stress resilience and circadian rhythm through the endocannabinoid system 00:05:20 – Why magnesium and NAD are the unsung heroes of travel recovery and energy 00:06:30 – Darin's morning elixir recipe: cacao, guarana, ashwagandha, chaga, ginseng, and monk fruit 00:08:00 – Hydration 101: how to use a manual RO filter, mineralize your water, and ditch plastic 00:10:00 – How to build nutrient density into travel days using chlorella, spirulina, Shakeology, and Barukas 00:12:00 – Travel nutrition sovereignty: packing your own snacks, fasting, and avoiding airline food 00:14:00 – Movement anywhere: Darin's “portable gym” using bungee cords and bodyweight routines 00:16:00 – The 3-hour morning ritual: NewCalm, Healing Codes, journaling, cacao, red light therapy, and breathwork 00:20:00 – How to avoid radiation scanners, mitigate EMFs, and use WaveGuard for energy field protection 00:22:00 – Why Darin microdoses nicotine for cognitive focus and immune modulation 00:23:00 – Breathing practices for immune strength: 3–4 rounds of 40 deep breaths, Wim Hof style 00:24:00 – How to pack fruit and salads in mason jars to stay hydrated and nourished on planes 00:26:00 – Grounding after flights: barefoot on the earth, morning sunlight, and re-aligning your circadian rhythm Thank You to Our Sponsors Manna Vitality: Go to mannavitality.com/ or use code DARIN20 for 20% off your order. Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway “Preparation is sovereignty. When you take responsibility for your nutrition, your hydration, and your energy before you travel, you're no longer surviving the trip — you're expanding through it.” Bibliography Martineau AR et al. Vitamin D supplementation to prevent acute respiratory infections: systematic review. BMJ. 2017. Goldenberg JZ et al. Probiotics for prevention of respiratory infections. Cochrane Database. 2017. Hemilä H. Vitamin C and zinc in common cold. Nutrients. 2017. Blessing EM et al. Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics. 2015. Morris HJ et al. Spirulina and chlorella as functional foods. Nutrients. 2022. Longo VD, Panda S. Fasting, circadian rhythms, and time-restricted feeding. Cell Metabolism. 2016. Booth FW et al. Waging war on physical inactivity. J Physiol. 2017. Balmori A. Electromagnetic pollution from radiofrequency fields. Pathophysiology. 2015. Kox M et al. Voluntary activation of sympathetic nervous system and attenuation of the innate immune response. PNAS. 2014.
El programa de hoy se emitió en vivo desde Tomelloso, en la provincia de Ciudad Real, con motivo de la Fiesta de la Vendimia, y aprovechamos para hablar precisamente de eso: del vino. Os contamos cuán antiguo es el vino, quiénes fueron sus inventores, según los últimos hallazgos arqueológicos. También os hablamos de cuál es el vino más antiguo que se ha conservado en estado líquido, una rareza que requiere de unas condiciones de conservación excepcionales. Si queréis leer los artículos científicos en que nos hemos basado, el primero es "Early Neolithic wine of Georgia in the South Caucasus", de Patrick McGovern et al. Lo podéis consultar gratuitamente en la página de PNAS: https://www.pnas.org/doi/full/10.1073/pnas.1714728114 El segundo es "New archaeochemical insights into Roman wine from Baetica", de Daniel Cosano et al. También lo podéis leer gratuitamente en la página del Journal of Archaeological Science: https://www.sciencedirect.com/science/article/pii/S2352409X24002645 Si os interesa la ciencia del vino, le dedicamos un episodio en nuestro pódcast hermano, La Brújula de la Ciencia: buscad allí el capítulo s11e09. Este programa se emitió originalmente el 2 de octubre de 2025. Podéis escuchar el resto de audios de Más de Uno en la app de Onda Cero y en su web, ondacero.es
Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Floss-based vaccination (Nat Biomed Engineering 2025) Press article on Floss-based vaccine paper (Sci News) Human milk IgA promotes immune development (PNAS 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
Where primates evolved Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Jorge Avaria-Llautureo and Chris Venditti explain why the evolution of primates likely occurred in cold, dry climates rather than in tropical forests. In this episode, we cover: •[00:00] Introduction •[00:58] Evolutionary biologist Jorge Avaria-Lautureo explains the prevailing hypothesis that primates evolved in a tropical climate •[02:54] Evolutionary biologist Chris Venditti introduces evidence suggesting a different origin climate. •[03:54] Avaria discusses how the researchers reconstructed the climate of early primate species. •[05:05] Venditti and Avaria explain why it was important to use standardized climate definitions in this study. •[07:29] Avaria describes the results of the study. •[08:18]Venditti talks about the importance of understanding early primates' climates. •[09:21] Avaria and Venditti talk about the study's caveats and limitations. •[10:22] Conclusion. About Our Guests: Jorge Avaria-Llautureo Postdoctoral scholar University of Reading Chris Venditti Professor University of Reading View related content here: https://www.pnas.org/doi/10.1073/pnas.2423833122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Die Themen in den Wissensnachrichten: +++ Neue Liebe steigert Zufriedenheit deutlich +++ Politische Feindseligkeit ist hartnäckig +++ Kopfstöße im Sport bringen schwere Schäden für das Gehirn +++**********Weiterführende Quellen zu dieser Folge:Mapping Life Satisfaction Over the First Years of Cohabitation Among Former Singles Living Alone in UK and Germany, Journal of Personality, 18.08.2025Why depolarization is hard: Evaluating attempts to decrease partisan animosity in America, PNAS, 23.9. 2025Repeated head trauma causes neuron loss and inflammation in young athletes, Nature, 17.09.2025Our actions are dictated by “autopilot”, not choice, finds new study, University of Surrey 18.09.2025Identification and Seasonal Abundance of Web- and Air-Borne Sex Pheromone Components of Western Black Widow Spiders, Latrodectus hesperus, Journal of Chemical Ecology, 12.03. 2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Die Themen in den Wissensnachrichten: +++ Mögliche Gründe für späte Jungfräulichkeit +++ Früher Kontakt mit Plastik kann Gesundheitsprobleme im Alter auslösen +++ Hummeln bestäuben Linden seit 24 Millionen Jahren +++**********Weiterführende Quellen zu dieser Folge:Life without sex: Large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNA, PNAS, 16.09.2025The effects of plastic exposures on children's health and urgent opportunities for prevention, The Lancet Child & Adolescent Health, 21.09.202524 million years of pollination interaction between European linden flowers and bumble bees, New Phytologist, 22.09.2025To Have and Have Not – How to Bridge the Gap in Opportunities, OECD, 22.09.2025A long-term ketogenic diet causes hyperlipidemia, liver dysfunction, and glucose intolerance from impaired insulin secretion in mice, Sciences Advances, 19.09.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices
Summary: Ants are some of the most misunderstood animals on Earth. Join Kiersten as she begins a new series about these fascinating insects. For my hearing impaired followers, a complete transcript of this podcast follows the show notes on Podbean Show Notes: “Tales from the Ant World” by Edward O. Wilson “Adventures Among Ants,” by Mark W. Moffett “In Search of Ant Ancestors,” by Ted R. Schultz, Proc Natl Acad Sci U S A. 2000 Dec 5;97(26):14028–14029. doi: 10.1073/pnas.011513798 “The abundance, biomass, and distribution of ants on Earth,” by Patrick Schultheiss, Sabine S Nooten, Runxi Wang, and Benoit Gurnard. PNAS, 119 (40) e2201550119, https://doi.org/10.1073/pnas.2201550119 Music written and performed by Katherine Camp Transcript (Piano music plays) Kiersten - Welcome to Ten Things I Like About… This is a podcast about misunderstood or unknown creatures in nature. Some we'll find right out side our doors and some are continents away but all are fascinating. My name is Kiersten and I have a Master's Degree in Animal Behavior and did my thesis on the breeding behavior of the Tri-colored bat. I was a zookeeper for many years and have worked with all sorts of animals from Aba Aba fish to tigers to ravens to domesticated dogs and so many more in between. Many of those years were spent in education programs and the most important lesson I learned was that the more information someone has about a particular animal the less they fear them. The less they fear them the more they crave information about them and before you know it you've become an advocate for that misunderstood animal. This podcast will focus ten, ten minute episodes on different animals and their amazing characteristics. Please join me on this extraordinary journey, you won't regret it. This is the beginning of a new series about a misunderstood animal that every one of us has encountered. Ants. Ants are one of the most misunderstood animals on the planet but they are so fascinating and very successful. In this series we are going to find out what makes them tick. The first thing I like about ants is their origins. As I begin this series I actually have a red, angry fire ant bite on my thumb. The irony is not lost on me that I am about to embark on a ten episode series dedicated to lauding the amazing attributes of ants to lure you into loving them while I have an itchy, painful welt from an ant bite on my thumb. These animals are truly fascinating so I bet I can get you to fall in love with them despite the nasty bites we've probably all experienced. Let's get started from the beginning shall we? The classification of ants is as follows: Kingdom Animalia (Animals) Phylum Arthropoda (Arthropods): invertebrate animals that have a segmented body and jointed appendages Subphylum Hexapoda (Hexapods): a six-legged arthropod Class Insecta (Insects) Order Hymenoptera (Ants, Bees, Wasps and Sawflies) Superfamily Formicoidea (Ants) Family Formicidae (Ants) The scientific names will vary based on species. When did ants first appear on the planet? They have been on the planet between 100 -150 million years ago. The specific timing has been hotly debated for many years until and amber sample was found by some rock hounds in 1966. This sample was discovered in Cliffwood Beach, New Jersey in the United States. It seemed an unlikely place to find what scientists needed to determine the origins of ants and it took twenty more years after the initial discovery to clarify whether this sample was of an ant or not. In 1986, it was confirmed to be the amber fossil of an ant solidifying the origins of ants in the mid-Cretaceous period, 90-94 million years ago. By the mid-Eocene period, approximately 50 million years ago, ants had achieved their current level of abundance. How many ants are on the planet today? In the summer of 2018, Edward O. Wilson, one of, if not the, foremost experts in the study of ants said in his book, Tales from the Ant World, that there are 15,438 species of ants in the world that have been recognized and given a Latinized name. Edward O. Wilson described 450 of known species of ants so I think we can take his word for when he says he's fairly certain there are approximately 25,000 species in existence today. A study published in 2022, says 15,700 species of ants have been identified. The numbers do see to be going up! The ant taxonomists working at Harvard University which has the world's largest collection of ants believe the figure to be between 25,000 to 30,000 different species of ants. To sum it up, there are a lot of ant species out there! Ants actually make up two-thirds of all insect life on Earth. We don't know have many individual ants are walking around on the Earth at this very moment, but it is in the billions possibly trillions. They are found on every single continent except Antarctica, but as soon as they figure out how to live in snow and ice, they'll be there too. They inhabit every habitat the planet has to offer from forests of all kinds, mountains ranges, deserts, prairies, and wetlands. There are even ants that scavenge for food underwater. They live underground, in the branches of trees, and inside caves. The eat seeds, fungi, animal protein, and insect protein. They are hunters, farmers, ranchers, and enslavers. They have one matriarch and live for the good of the colony. Ants are unbelievably complicated life forms and I can't wait to take you on a journey you won't forget. Thanks for joining me for the first episode of ants. My first favorite thing about this misunderstood insect is their origins. If you're enjoying this podcast please recommend me to friends and family and take a moment to give me a rating on whatever platform your listening. It will help me reach more listeners and give the animals I talk about an even better chance at change. Join me next we for another exciting episode about ants. (Piano Music plays) This has been an episode of Ten Things I like About with Kiersten and Company. Original music written and performed by Katherine Camp, piano extraordinaire.
5—6—3—4—3—1—7—2In the first episode under our new podcast name (it's now the Science Fictions podcast!), we ask whatever happened to all those games that claimed to tell you your “brain age”—games that turned into a whole scientific literature on brain training. We discuss: the still-unresolved question of whether training one specific cognitive ability makes you generally smarter; seemingly endless contrasting meta-analyses; and the small matter of what brain training might tell us about the nature of intelligence.(If you can repeat the list of numbers from the top in reverse order then you have the brain of a 25-year-old. If you're 25 or younger, then I don't know what to tell you.)We're now an official part of the Works in Progress podcast world. You can find their other podcasts, including Hard Drugs, the one we talked about on today's episode (about the remarkable development of a drug for HIV), at podcast.worksinprogress.co. Show notes* The 2008 PNAS paper that started the craze for working memory training* The under-discussed rebuttal* 2013 meta-analysis concluding there's no evidence for far transfer* 2015 meta-analysis concluding there is no convincing evidence brain training is effective* 2016 meta-analysis saying there is no convincing evidence brain training is NOT effective* Very useful and detailed 2016 review of the evidence and the methodological issues inherent in brain training (including active vs. passive control groups)* 2020 meta-meta-analysis arguing that the active-passive distinction doesn't matter* 2023 review criticising the meta-meta-analysis* And the authors' own 2020 meta-analysis* 2022 meta-analysis of commercial brain training in older peopleCreditsThe Science Fictions podcast is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit sciencefictionspod.substack.com/subscribe
Climate change and lake oxygenation Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Joachim Jansen explains how climate change altered cycles of oxygenation in lakes. In this episode, we cover: •[00:00] Introduction. •[00:56] Limnologist Joachim Jansen introduces us to the cycles of oxygenation in lakes throughout the seasons. •[02:35] He describes previous hypothesis about climate change and lake oxygenation and introduces the methods and datasets of the study. •[04:59] Jansen introduces the results of the study, including key differences between large and small lakes. •[06:54] He talks about the consequences of deoxygenation. •[09:03] Jansen explains the caveats and limitations of the study. •[09:37] Conclusion. About Our Guest: Joachim Jansen Postdoctoral Researcher University of Helsinki View related content here: https://www.pnas.org/doi/10.1073/pnas.2426140122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
What if our memories weren't fixed, but flexible? And what if the key to understanding fear, emotion, and consciousness lies in how the brain constantly reshapes experience?In this episode of Mind-Body Solution, Dr Tevin Naidu speaks with Prof Daniela Schiller, a world-renowned neuroscientist, and director of the Laboratory of Affective Neuroscience at Mount Sinai. Prof Schiller's groundbreaking work explores how we form, change, and even reimagine emotional memories, from the neuroscience of fear to the dynamic nature of consciousness and identity. Together, we dive into:- How fear memories are formed in the brain- Why emotional responses are flexible, not hardwired- The ethics of modifying traumatic memories- Social navigation: how the brain maps human relationships- The Human Affectome: a bold framework linking emotion and consciousness- Can machines ever be conscious? Free will, probabilities, and neuroscience- Memory as liberation: how to live with multiple stories of the selfProf Schiller is not only a world-leading neuroscientist with work published in Nature, Neuron, Nature Neuroscience, and PNAS, she's also a Fulbright Fellow, Kavli Frontiers of Science Fellow, two-time Moth StorySLAM winner, and drummer for the rock band "The Amygdaloids".TIMESTAMPS:(0:00) – Introduction: Daniela Schiller on the Science of Emotion & Memory(0:39) – From Animal Models to Human Fear Studies: Schiller's Journey(2:00) – What Happens in the Brain When a Fear Memory is Formed?(3:15) – Flexibility of Emotional Responses: Why Fear Is Not Hardwired(4:51) – Computational Psychiatry & the Brain as an Algorithmic System(6:00) – From Circuits to Consciousness: Can Neuroscience Explain Subjective Experience?(7:11) – The Human Affectome: A Framework Linking Emotion and Consciousness(9:13) – What Is Consciousness? Felt Experience as the Core of Mind(11:04) – Social Navigation: Mapping Human Relationships in the Brain(14:02) – How Social Media Distorts Real Interaction and Social Space(18:15) – Ethics of Modifying Traumatic Memories: Liberation or Risk?(21:27) – Are Emotions Brain Events, Bodily Events, or Psychological Phenomena?(23:16) – The 4E Approach: Embedded, Embodied, Enactive, and Extended Cognition(24:00) – Bringing Philosophy Into Neuroscience: The Human Affectome Project(27:03) – Exciting Advances: Intracranial Recordings, VR, and Naturalistic Neuroscience(33:11) – Can Artificial Intelligence or Machines Ever Be Conscious?(36:26) – Free Will and Probabilities: Neuroscience Meets Philosophy(41:12) – Overcoming Fear as Liberation: Redefining Memory and Identity(46:09) – Living With Multiple Stories: Memory, Authenticity, and Self-Creation(1:02:24) – Future Directions: Reconsolidation, Social Space, and the Human AffectomeEPISODE LINKS:- Daniela' Website: https://profiles.mountsinai.org/daniela-schiller- Daniela's Lab: https://labs.neuroscience.mssm.edu/project/schiller-lab/- Daniela's Publications: https://www.ncbi.nlm.nih.gov/myncbi/daniela.schiller.2/bibliography/public/CONNECT:- Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
Inflammation is the body's natural way of healing, but when it becomes chronic and hidden, it quietly drives many of today's most common health problems—heart disease, diabetes, dementia, cancer, autoimmune conditions, and more. Unlike the redness and swelling from a cut or sprain, this “silent inflammation” often goes unnoticed while slowly damaging tissues and speeding up aging. Modern life fuels the fire: processed foods, food additives, pollution, plastics, chronic stress, too much sitting, and poor sleep. The good news is inflammation can be calmed by simple daily choices—eating colorful whole foods like berries, leafy greens, beans, nuts, seeds, and omega-3 rich fish; adding herbs and spices like turmeric and cumin; moving regularly; practicing relaxation; and repairing gut health. Even small shifts, like climbing stairs, eating within a shorter window, or reducing sugar, can make a big difference. By lowering inflammation, the body finds balance again, opening the door to more energy, resilience, and healthy aging. In this episode, I discuss, along with Dr. Shilpa Ravella and Dr. David Furman, why it's important to be aware of systemic inflammation and how to address it. Dr. Ravella is a gastroenterologist and Assistant Professor of Medicine at Columbia University Medical Center. She is the author of A Silent Fire: The Story of Inflammation, Diet & Disease, which investigates inflammation—the hidden force at the heart of modern disease. Her writing has appeared in The Atlantic, New York Magazine, The Wall Street Journal, TIME, Slate, Discover, and USA Today, among other publications. Dr. David Furman is Associate Professor and Director of the Bioinformatics Core at the Buck Institute for Research on Aging, as well as the Director of the Stanford 1000 Immunomes Project. He obtained his doctoral degree in immunology from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans. He has published nearly thirty scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:What Causes Inflammation And How Can You Treat It? The Silent Killer: Inflammation And Chronic Disease How Silent Inflammation Accelerates Aging
Die Themen in den Wissensnachrichten: +++ Auch Klimaveränderungen haben in der Vergangenheit wohl politische Krisen verschärft +++ Langer Konkurrenzdruck kann negative Folgen für Jugendliche haben +++ Bei Reiseübelkeit: Fröhliche Musik hören? +++ **********Weiterführende Quellen zu dieser Folge:A climate of conflict: How the little ice age sparked rebellions and revolutions across Europe, Global and Planetary Change, 24.08.2025The persistent effect of competition on prosociality. Fabian Kosse, Ranjita Rajan, and Michela Tincani, Journal of the European Economic Association, 04.08.2025A study on the mitigating effect of different music types on motion sickness based on EEG analysis, Frontiers in Human Neuroscience, 03.09.20258,000 years of wild and domestic animal body size data reveal long-term synchrony and recent divergence due to intensified human impact, PNAS, 02.09.2025Snowfall decrease in recent years undermines glacier health and meltwater resources in the Northwestern Pamirs, Communications Earth & Environment, 02.09.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
In our last standard episode, we talked about retraction—removing papers from the scientific literature. Well, it turns out there's an awful lot of retraction to do, in large part due to paper mills. These are fraudulent enterprises that take money from nefarious scientists to put their name on fake scientific papers, and get them published in whatever journal will accept them. Sadly, paper mill papers are now rife. In this solo episode of The Studies Show (Tom is away at a wedding), Stuart talks through a new paper showing just how badly these paper mills have poisoned the scientific literature.Show notes* The new PNAS paper using various techniques to examine coordinated attempts at scientific fraud* A response from PLOS* The Retraction Watch article on ARDA* A few interesting recent articles on paper mills* The Nature News article on the universities with the most retractions* AI versus paper millsCreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe
Die Themen in den Wissensnachrichten: +++ Wichtige Meeresströmung im Golf von Panama fast komplett ausgefallen +++ KI-Stethoskop kann bei Diagnose von Herzproblemen helfen +++ Spinne setzt Glühwürmchen als Köder ein +++**********Weiterführende Quellen zu dieser Folge:Unprecedented suppression of Panama's Pacific upwelling in 2025, PNAS, 02.09.2025Schwächere Passatwinde verhindern Tiefenwasserauftrieb im Golf von Panama, idw - Informationsdienst Wissenschaft, 02.09.202516 % der Studierenden brauchen eine Stunde oder länger für den Weg zur Hochschule, DESTATIS, 02.09.2025Humble stethoscope gets an upgrade: AI helps it detect three heart conditions in 15 seconds, Medical Xpress, 30.08.2025Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER): design and rationale for a decentralised, real-world cluster-randomised controlled trial and implementation study, BMJ Open, 21.05.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
The physics of the squash nick shot Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Roberto Zenit explains the physics behind the unanswerable nick shot in the game of squash. In this episode, we cover: •[00:00] Introduction. •[00:56] Engineer Roberto Zenit introduces the game of squash, including his participation in the sport, and introduces the nick shot. •[02:11] He talks about the background and methods of the study. •[04:50] Zenit describes the mechanics of a nick shot. •[06:01] He talks about the implications of the study for squash players and for other applications. •[08:52] Zenit recounts the caveats and limitations of the study. •[09:41] Conclusion. About Our Guests: Roberto Zenit Professor Brown University View related content here: https://www.pnas.org/doi/10.1073/pnas.2505715122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Fungal infections and disease have long been overlooked in terms of healthcare burden, with poor diagnostics and limited options for treatment and management. In 2022, the WHO published its first Fungal Priority Pathogens List as an effort to establish a global prioritised framework that addresses unmet research and development needs in fungal disease and antifungal resistance, as well as guides public health action [1]. In this episode of Communicable, Angela Huttner and Josh Nosanchuk invite Hatim Sati (WHO), the project lead in creating this list, and Dimitrios Kontoyiannis (MD Anderson Cancer Center, Houston, Texas), a clinician researcher studying fungal diagnostics and antifungal discovery, for a candid discussion on the making of and relevance of such a list. Apart from reviewing the fungal pathogens, the conversation also covers limitations of the list, what to expect for the next iteration, contextualising the list in one's local region, and the impact the list has had already on research funding and public awareness.This episode was edited by Kathryn Hostettler and peer reviewed by Andrisa Xhaxha from Elbasan, Albania. ReferencesWHO fungal priority pathogens list to guide research, development and public health action. Geneva: World Health Organization; 2022. Related podcast episodesCommunicable Episode 31: Climate change and fungal spread https://share.transistor.fm/s/db58f558 Communicable Episode 08: The nightmare series, part 1 – how to deal with Candida auris https://share.transistor.fm/s/c0616c4d Further reading Seidel D, et al. Impact of climate change and natural disasters on fungal infections. Lancet Microbe 2024. DOI: 10.1016/S2666-5247(24)00039-9Fisher MC and Denning DW. The WHO fungal priority pathogens list as a gamechanger. Nat Rev Microbiol 2023. DOI: 10.1038/s41579-023-00861-xShor E, et al. Tolerance and heteroresistance to echinocandins in Candida auris: conceptual issues, clinical implications, and outstanding questions. mSphere 2025. DOI: 10.1128/msphere.00161-25Panackal AA, et al. Geoclimatic influences on invasive aspergillosis after hematopoietic stem cell transplantation. Clin Infect Dis 2010. DOI: 10.1086/652761Lázár-Molnár E, et al. The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum. PNAS 2008. DOI: 10.1073/pnas.0711918105Mashal M, “A potentially fatal fungal infections cropping up among India's Covid patients.” New York Times 2021. https://www.nytimes.com/2021/05/09/world/india-covid-mucormycosis.html Thevissen K, et al. International survey on influenza-associated pulmonary aspergillosis (IAPA) in intensive care units: responses suggest low awareness and potential underdiagnosis outside Europe. Crit Care 2020. DOI: 10.1186/s13054-020-2808-8Pappas PG, et al. Clinical mycology today: A synopsis of the mycoses study group education and research consortium (MSGERC) second biennial meeting, September 27–30, 2018, Big Sky, Montana, a proposed global research agenda. Medical Mycology 2020. DOI: 10.1093/mmy/myaa034Hostettler K, et al. Communicable Episode 31: Climate change and fungal spread. CMI Communications 2025. DOI: 10.1016/j.cmicom.2025.105126
A pterosaur and its ecosystem at the end of the Triassic Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Kay Behrensmeyer and Ben Kligman describe what a fossil bone bed in Arizona reveals about a 209-million-year-old pterosaur and its ecosystem. In this episode, we cover: •[00:00] Introduction •[01:01] Paleoecologist Kay Behrensmeyer and paleontologist Ben Kligman describe the discovery of this fossil bone bed. •[03:10] Kligman and Behrensmeyer introduce a previously undescribed pterosaur. •[05:00] They talk about what this specimen says about the ecology and evolution of pterosaurs. •[06:15] Kligman and Behrensmeyer talk about the importance of studying this fossil community. •[07:52] They explain how their methods can improve paleontology and discovery of small fossils. •[09:08] Behrensmeyer and Kligman talk about the study's caveats and limitations. •[10:10] Conclusion. About Our Guests: Kay Behrensmeyer Curator of Paleobiology National Museum of Natural History, Smithsonian Institution Ben Kligman Postdoctoral Fellow National Museum of Natural History, Smithsonian Institution View related content here: https://www.pnas.org/doi/10.1073/pnas.2505513122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Dan and James chat about a a new 'pop-up journal' concept for addressing specific research questions. They also answer a listener question from a journal grammar editor and discuss a new PNAS article on paper mills Links * The pop-up journal (https://popupjournal.com) * The episode (https://everythinghertz.com/58) where Dan's wife went into labor * The PNAS paper mill paper (https://www.pnas.org/doi/10.1073/pnas.2420092122) * A blog post (https://reeserichardson.blog/2025/08/04/a-do-or-die-moment-for-the-scientific-enterprise/) from the PNAS paper lead author, Reese Richardson. * The Nature piece (https://www.nature.com/articles/d41586-025-02446-5) on the paper Social media links - Dan on Bluesky (https://bsky.app/profile/dsquintana.bsky.social) - James on Bluesky (https://bsky.app/profile/jamesheathers.bsky.social) - Everything Hertz on Bluesky (https://bsky.app/profile/hertzpodcast.bsky.social) Citation Quintana, D. S., & Heathers, J. (2025, August 7). 193: The pop-up journal, Everything Hertz [Audio podcast], DOI: 10.17605/OSF.IO/2ZMQ7
Recognizing a familiar voice is one of the brain's earliest social feats. But what are the brain circuits that let a newborn pick out mom in a crowded nursery? How do they change as kids turn toward friends and the wider world? And what are we learning about why this instinct fails to develop in the autistic brain?This week, host Nicholas Weiler joins Stanford neuroscientist Dan Abrams on the quest to understand the neural “hub” that links our brains' hearing centers to the networks that tag voices as rewarding, social, and worth our attention. The findings could reshape early-intervention strategies for kids on the spectrum.Learn MoreStanford Speech and Social Neuroscience LabParticipate in a StudyCommunity Support ResourcesPublicationsUnderconnectivity between voice-selective cortex and reward circuitry in children with autism (PNAS, 2013) Neural circuits underlying mother's voice perception predict social communication abilities in children (PNAS, 2016) Impaired voice processing in reward and salience circuits predicts social communication in children with autism (eLife, 2019) A Neurodevelopmental Shift in Reward Circuitry from Mother's to Nonfamilial Voices in Adolescence (Journal of Neuroscience, 2022)Stanford Coverage"The teen brain tunes in less to Mom's voice, more to unfamiliar voices, study finds" (Stanford Medicine, 2022)"Brain wiring explains why autism hinders grasp of vocal emotion, says Stanford Medicine study" (Stanford Medicine, 2023)We want to hear from your neurons! Email us at at neuronspodcast@stanford.eduSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
The postglacial history of the Saimaa ringed seal Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Jaakko Pohjoismäki, Jukka Jernvall, and Ari Löytynoja discuss the evolutionary history of the Saimaa ringed seal. In this episode, we cover: •[00:00] Introduction •[01:06] Molecular biologist Jaakko Pohjoismäki introduces Lake Saimaa and the Saimaa ringed seal. •[02:30] Zoologist Jukka Jernvall talks about the characteristics of species isolated by glaciation. •[03:27] Evolutionary biologist and bioinformatician Ari Löytynoja explains the genetic and demographic methods of the study. •[04:11] Löytynoja and Jernvall explain why the results were surprising and where the study turned next. •[06:20] Pohjoismäki and Löytynoja describe the study's implications for biodiversity in postglacial habitats. •[07:50] Jernvall and Löytynoja talk about the study's caveats and limitations. •[10:14] Conclusion. About Our Guests: Jaakko Pohjoismäki Professor University of Eastern Finland Jukka Jernvall Professor University of Helsinki Ari Löytynoja University Lecturer University of Helsinki View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2503368122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Dr. Tracey Shors is a Distinguished Professor in Behavioral and Systems Neuroscience in the Department of Psychology at Rutgers University, where she is also a member of the Center for Collaborative Neuroscience. Dr. Shors has more than 150 scientific publications in journals including Nature, Science, PNAS and Nature Neuroscience, and her research findings have been featured in popular publications such as Scientific American, The New York Times, The Washington Post, and on NPR and CNN. Her research efforts were recently recognized with W. Horsley Gantt Medal from the Pavlovian Society for the"noble pursuit of truth."Dr. Shors' research program studies how our brains learn, including how they learn to ruminate on trauma-related memories and how this process can interfere with our everyday lives, while making still more memories. Dr. Shors is also focused on identifying effective tools for reducing repetitive thoughts that reinforce our everyday traumas. Her popular press book, Everyday Trauma (Flatiron,2021), reviews the causes and consequences of trauma as well as the most effective treatments. It has been translated in six languages. Her brain fitness program, known as MAP Train My Brain combines “mental and physical” training with silent meditation and aerobic exercise to enhance brain health through effortful learning. To try out her free 6-week online course, sign up at maptrainmybrain.com.Dr. Tracy Shor's InstagramSupport the show
Managing eastern black rhinoceros populations with genetic studies Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Barbara Mable and Ronald Mellya show how allowing endangered rhinos to move between populations enhances genetic diversity. In this episode, we cover: •[00:00] Introduction •[01:00] Evolutionary geneticist Barbara Mable explains why is genetic diversity important in managing small, isolated populations of rhinos. •[02:59] Park warden Ronald Mellya describes how his firsthand experience with rhino management led to this study. •[04:52] Mable explains the methods of the study and the contributions of co-author Anubhab Khan. •[06:20] Mable talks about the results. •[07:24] Mellya tells how the study has changed rhino management in Tanzania. •[08:37] Mable and Mellya enumerate the caveats and limitations of the study. •[10:20] Conclusion. About Our Guests: Barbara Mable Professor University of Glasgow Ronald Mellya Park Warden Tanzania National Parks View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2414412122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
The adaptability of fungi to warmer temperatures is an obvious consequence of climate change. Perhaps less obvious is the role climate change has played on fungal pathogens emerging as a global health concern. While humans are mostly protected from fungal infections by our immune system and body temperature, a warming global climate could subvert the status quo. Some fungi are already adapted to warmer temperatures and causing invasive acute infections in humans: Candidozyma auris, Cryptococcus neoformans, and Aspergillus fumigatus, to name a few. In this episode of Communicable, Angela Huttner and Josh Nosanchuk invite Arturo Casadevall, a Bloomberg Distinguished Professor at Johns Hopkins and this year's recipient of ESCMID's Excellence in Science Award, to discuss the world of fungi and their pathogenic potential in a warming world. Other topics include how to prepare for their emergence as a health threat, how fungi can be harnessed for applications that can benefit us, and ultimately answering the question Casadevall himself posed in the title of his recently published book, What if fungi win?This episode was edited by Kathryn Hostettler and peer reviewed by Robin Aerts of University Hospital Antwerp, Belgium. References1. Casadevall, A with Desmon S. What if fungi win? Johns Hopkins University Press, 2024.2. Smith DFG, et al. Environmental fungi from cool and warm neighborhoods in the urban heat island of Baltimore City show differences in thermal susceptibility and pigmentation. BioRxiv 2025. DOI: 10.1101/2023.11.10.566554 3. Casadevall A and Pirofski L. Benefits and Costs of Animal Virulence for Microbes. mBio 2019. DOI: 10.1128/mBio.00863-194. Cordero RJB et al. Radiation protection and structural stability of fungal melanin polylactic acid biocomposites in low Earth orbit. PNAS 2025. DOI: 10.1073/pnas.24271181225. Dadachova E, et al. The radioprotective properties of fungal melanin are a function of its chemical composition, stable radical presence and spatial arrangement. Pigment Cell Melanoma Res 2008. DOI: 10.1111/j.1755-148X.2007.00430.x6. Cordero RJB et al. The hypothermic nature of fungi. PNAS 2022. DOI: 10.1073/pnas.2221996120
An experimental drug called NU-9 was invented at Northwestern University by Richard Silverman, PhD. It has been approved for clinical trials for the treatment of ALS and found to improves neuron health in animal models of Alzheimer's disease according to a new Northwestern Medicine study published in PNAS. This discovery is giving scientists hope that the drug could be effective in multiple neurodegenerative diseases by addressing the underlying mechanisms of these diseases. Silverman and Northwestern University Alzheimer disease expert, William Klein, PhD, discuss the potential of NU-9 in this episode.
A reference genome aids efforts to rescue the northern white rhinoceros Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Franz-Josef Müller explains genomic tools to aid the functionally extinct northern white rhinoceros. In this episode, we cover: •[00:00] Introduction •[01:11] Multidisciplinary scientist Franz-Josef Müller introduces the northern white rhinoceros. •[01:55] He introduces induced pluripotent stem cells and why they're important in efforts to save the northern white rhinoceros. •[04:20] He talks about the genomic risks of using induced pluripotent stem cells •[05:21] Müller tells the story of how he and his colleagues came together to complete the study. •[06:36] He explains how the northern white rhino's genome was sequenced. •[07:58] He talks about the results and implications for stem cell genomic integrity. •[08:51] Müller enumerates the caveats and limitations of the study. •[10:24] Conclusion. About Our Guest: Franz-Josef Müller Professor University Hospital Schleswig-Holstein View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2401207122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
How we sleep tonight shapes how we move tomorrow!
The boys discuss the secret to a happy life, where to find the most psychopaths, the robot workforce, why other countries hate American tourists, Robert Pattinson, and Raj's new special!The Treehouse is a daily DFW based comedy podcast and radio show. Leave your worries outside and join Dan O'Malley, Trey Trenholm, Raj Sharma, and their guests for laughs about current events, stupid news, and the comedy that is their lives. If it's stupid, it's in here.The Treehouse WebsiteGet 60% off the Magic Mind offer with our link and code: https://magicmind.com/ttsmf & TREEHOUSE60 #magicmind #mentalwealth #mentalperformanceGet a FREE roof inspection from the best company in DFW:Cook DFW Roofing & Restoration Defender OutdoorsUse code TREEHOUSE to unlock special discounts at Defender Outdoors!CLICK HERE TO DONATE:The RMS Treehouse Listeners FoundationLINKS:This One Trait Can Boost Your Happiness At Any Age, New Study FindsAmazon is reportedly training humanoid robots to deliver packages | The VergeDowntown Brooklyn Target's Window-Washing Drones Go ViralAversive societal conditions explain differences in “dark” personality across countries and US states | PNAS
Water and the possibility of life on Mars Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explain what we know about the potential for water and life on Mars and what we might learn from analysis of returned samples. In this episode, we cover: •[00:00] Introduction •[01:04] Mark Thiemens explains the importance of bringing samples from Mars back to Earth. •[02:37] Arya Udry explains the current gaps and limitations in the geological record provided by Martian meteorites. •[03:55] Bruce Jakosky explains what we currently know about the presence and history of water on Mars. •[05:26] Monica Grady explains how analyzing volatile species in Martian samples could provide insight into the planet's past climate. •[06:58] Rachel Slank describes the potential presence of liquid brines on Mars. •[08:27] Vashan Wright used recordings from a seismometer onboard NASA's InSight lander to estimate the volumes of liquid water that might be contained in the Martian mid-crust. •[10:14] Mark Sephton explains what biomarkers are and what kinds we might expect to find in Martian samples. •[11:34] Caroline Freissinet describes the discovery of long-chain organic molecules on Mars and the difficulties of conclusively identifying organic molecules as biomarkers. •[13:32] Thiemens explains the potentially far-reaching value of continuing to support the Mars Sample Return mission. •[14:37] Final thoughts and conclusion. About Our Guest: Mark Thiemens Distinguished Professor of Chemistry and Biochemistry University of California at San Diego Arya Udry Associate Professor – Graduate coordinator University of Nevada, Las Vegas Bruce Jakosky Professor Emeritus University of Colorado Boulder Monica Grady Professor Emirita Open University Rachel Slank Postdoctoral Fellow Lunar and Planetary Institute Vashan Wright Assistant Professor University of California, San Diego Mark Sephton Professor Imperial College London Caroline Freissinet Researcher Laboratory for Atmospheres, Observations, and Space French National Centre for Scientific Research View related content here: https://www.pnas.org/doi/10.1073/pnas.2421996121 https://www.pnas.org/doi/10.1073/pnas.2415280121 https://www.pnas.org/doi/full/10.1073/pnas.2404254121 https://www.pnas.org/doi/full/10.1073/pnas.2321080121 https://www.pnas.org/doi/full/10.1073/pnas.2404260121 https://www.pnas.org/doi/full/10.1073/pnas.2321067121 https://www.pnas.org/doi/full/10.1073/pnas.2409983121 https://www.pnas.org/doi/full/10.1073/pnas.2404256121 https://www.pnas.org/doi/full/10.1073/pnas.2420580122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
All the colours of the rainbow, plus oneResearchers have fired lasers directly into the eye to stimulate photoreceptors, and produce the perception of a colour that does not exist in nature. They describe it as a “supersaturated teal,” and hope the technique will allow them to better understand colour vision and perhaps lead to treatments for vision problems. Austin Roorda has been developing this technology using mirrors, lasers and optical devices. He is a professor of Optometry and Vision Science at University of California, Berkeley. The study was published in the journal Science Advances.Following in the footsteps of an ancient ankylosaurPaleontologists have found fossil footprints of an armoured dinosaur in the Canadian Rockies that fill in a critical gap in the fossil record. The footprints belonged to a club-tailed ankylosaur about five to six metres long, and are the first evidence of this type of dinosaur living in North America in a period known as the middle Cretaceous. The research was led by Victoria Arbour, curator of paleontology at the Royal B.C. Museum, and published in the journal Vertebrate Paleontology.Did the Neanderthals die from sunburn?Neanderthals disappeared 40,000 years ago, and new research suggests this corresponds to a period of weakness in the Earth's magnetic field that allowed an increase in the solar radiation reaching the surface. Researchers think they have evidence that modern humans were able to protect themselves from the sun better than Neanderthals could, and this might have contributed to the Neanderthal extinction. Raven Garvey is an anthropologist at the University of Michigan. Her team's research was published in the journal Science. Cloudy with a chance of ammonia mushballsNew observations and models of activity within Jupiter's stormy atmosphere is giving a weather report for the giant planet, and it's pretty extreme. Most interestingly, researchers predict conditions that could lead to violent lightning storms producing softball sized frozen ammonia “mushballs” that would rain through the upper atmosphere. The research was led by Chris Moeckel, a planetary scientist and aerospace engineer at the University of California-Berkeley Space Sciences Laboratory, and was published in the journal Science Advances.Shattering heat records: climate change is turning out to be worse than expectedIn the last few years, we've seen global temperatures rising faster, with more extreme localized heatwaves, than climate models predicted. Climate scientists are trying to understand this by investigating the underlying factors behind these heating trends. Richard Allan, from the University of Reading in the U.K., was expecting a larger than normal rise in global temperatures due to natural fluctuations, but global temperatures in 2023 and 2024 were much higher than expected. Their recent study in the journal Environmental Research Letters found a growing imbalance in the earth's heat system, with increasingly more heat coming in than leaving, in large part due to changes we've seen in global cloud cover.This global heating is not happening evenly around the world. Kai Kornhuber, from the International Institute for Applied Systems Analysis in Austria and Columbia Climate School in New York, found regional hotspots that are experiencing unexpected extreme heat, likely due to a combination of factors. That study is in the journal PNAS.
Most iguanas are indigenous to the Americas. So how did the Fijian species end up on the island, nearly 5000 miles away in the South Pacific? According to a new study in the journal PNAS, it was probably via raft ... that is, on clump of floating trees. And this rafting hypothesis isn't entirely unprecedented. After hurricanes Luis and Marilyn hit the Caribbean in the 1990s, researchers found that a group of iguanas had floated over 180 miles away from Guadeloupe to the territory of Anguilla. Want to hear more about iguanas? Or rafts? Or evolutionary biology? Email us at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy