Podcasts about pnas

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Latest podcast episodes about pnas

Live Longer World
MIT Scientist: This Hidden Molecule Fuels Cancer (And It's In Your Supplements) | Stephanie Seneff

Live Longer World

Play Episode Listen Later Jun 10, 2026 110:06


Is a hidden molecule in your food and water silently fueling cancer, Alzheimer's, and Parkinson's? Could the supplements you trust every day be making it worse?Dr. Stephanie Seneff is a senior research scientist at MIT (published in PNAS, Frontiers, FASEB) with a career studying nutrition, biology, and toxicology. In this conversation, she explains why deuterium — a heavier form of hydrogen — may be the most underrated driver of chronic disease, why cancer might be the body's repair response to deuterium-damaged mitochondria, and why most supplements may backfire.We discuss:◾ Why deuterium may be the most important molecule you've never heard of◾ How glyphosate stops your body from clearing deuterium◾ The two supplements you should stop taking immediately◾ Why she says: "I don't believe in supplements"◾ Why chemo may be working backwards on cancer◾ How to make your gut produce low-deuterium water◾ The folic-acid-in-pregnancy and autism connection◾ Why she drinks deuterium-depleted water every dayThis is Dr. Seneff's second appearance on Live Longer World. Her first episode on glyphosate is linked below.Episode Show Notes: https://livelongerworld.com/p/sseneff2Find me on X: https://x.com/aasthajs My health stack: https://www.healthstacked.com/aasthajsTIMESTAMPS:0:00 Why deuterium might be the most important molecule you've never heard of5:09 The hidden reason processed food is wrecking your health7:25 How deuterium breaks your mitochondria11:02 Glyphosate stops your body from rationing deuterium (and the osteoporosis link)18:23 Health Stacked19:07 No one is connecting gut health to deuterium, until now22:45 The two nutrients that help your gut clear deuterium25:29 Methylation, melatonin, and protecting your mitochondria33:14 Why melatonin supplements don't actually work34:08 The two supplements you should stop taking immediately38:06 How to make your gut produce low-deuterium water41:12 How glyphosate suppresses your MTHFR gene43:21 Why folate supplementation is a problem45:06 "I don't believe in supplements", Stephanie's case against them46:02 Why she's suspicious of fish oil47:47 The folic-acid-in-pregnancy and autism connection52:37 How glyphosate is quietly causing bone problems56:22 Inflammation is really a deuterium problem1:01:25 Gerald Pollack's EZ water and how your cells expel deuterium1:04:59 Why breast milk is low in deuterium1:09:03 Cancer's real job: repairing your mitochondria (and why chemo may be a mistake)1:23:14 How deuterium-depleted water may help heal cancer1:26:57 Deuterium and Parkinson's: how plaque traps it1:30:37 How to fight Parkinson's1:33:55 Why Stephanie drinks deuterium-depleted water every day1:36:37 What glyphosate does to your sulfation system1:38:38 How grounding reduces deuterium1:39:42 Jack Kruse on glyphosate and melanin1:40:08 Are seed oils high in deuterium? 1:45:05 Does where you live (and sunlight) affect your deuterium?1:47:05 Practical tips to manage your deuterium loadDr. STEPHANIE SENEFF:Website: https://stephanieseneff.net/X: https://x.com/stephanieseneffAASTHA, LIVE LONGER WORLD:Join 2,000+ others for practical health protocols on circadian alignment, light, sleep, & non-toxic living: https://livelongerworld.com/X: https://x.com/aasthajs Instagram: https://www.instagram.com/aasthajs/My health stack: https://www.healthstacked.com/aasthajsIntroducing HEALTH STACKED: https://www.healthstacked.com/I built the health store I've always wanted. Health Stacked is a vetted marketplace of 500+ health & longevity products across 12 categories like sleep, fitness, non-toxic home, lighting & EMF, and more. Products are screened for plastic, PFAS, and 20+ toxins. Inclusion is 100% merit-based. And every product has been hand-picked by me.RELATED EPISODES:Glyphosate Toxicity & Deuterium's Role in Cancer, Celiac, Aging | Dr. Stephanie Seneff: https://open.spotify.com/episode/4HFmNT0fLCckXvrC1XRSFt?si=cSv7wuPPTm2wE5YSMY2L3w

RSM River Mechanics Podcast
Floodplain Sedimentation Pannel with Desiree Tullos, Janine Castro, and Jon Czuba

RSM River Mechanics Podcast

Play Episode Listen Later Jun 8, 2026 63:53


About a year ago an interdisciplinary tam at Oregon State invited a collection of subject matter experts for workshop on floodplain sedimentation processes.  The workshop took up a very specific question but gathering this much expertise on floodplain landforms and processes generated a wide-ranging discussion of how floodplains work, how to restore them, and even what they are.  So when Desiree Tullos reached out and invited me I brought my podcast gear in just in case… And I just found the discussions so useful that I wanted to share it with the other practitioners that have gathered around this podcast project.  We have spent a lot of time talking about channel form, function, and process on this podcast, I couldn't pass up the chance to give some time to these other, underrated, river landforms. So I asked three of the participants:  Dr. Desiree Tullos, Dr. Janine Castro and Dr. Jonathan Czuba if they'd be willing to debrief the themes and take aways from the gathering…and I think did a fantastic job replicating a lot of the value I got out of being at this workshop in this interview, with almost no prep.Desiree Tullos is a professor of Biological and Ecological Engineering at Oregon State and was one of the point people responsible for convening and imagining this workshop. Her research emphasizes sustainable engineering and management of rivers by examining the intersections of hydraulics, infrastructure, ecology, and society, and heavily emphasizes engaging and mentoring undergraduate students in research with societal relevance. Janine Castro is co-founder and Technical Director of the River Restoration Program at Portland State University and is one of the five founding members of River Restoration Northwest.  She recently retired from Federal service, where she worked as a geomorphologist for 34 years.Jon Czuba spent most of his 20 years measuring, modeling, and analyzing sediment transport across the U.S.  as a Professor of Ecological Engineering in the Department of Biological Systems Engineering at Virginia Tech.  He recently received an early career research award from the Universities Council on Water Resources for his work including publications in Science, Nature, and PNAS.This is a link to a version of the talk I gave at this workshop on floodplain modeling and processes: https://youtu.be/keGQviqInR0This series was funded by the Regional Sediment Management (RSM) program.Mike Loretto edited the first three seasons and created the theme music.Tessa Hall is editing most of Season 4.Stanford Gibson (HEC Sediment Specialist) hosts.Video shorts and other bonus content are available at the podcast website:https://www.hec.usace.army.mil/confluence/rasdocs/rastraining/latest/the-rsm-river-mechanics-podcast...but most of the supplementary videos are available on the HEC Sediment YouTube channel:https://www.youtube.com/user/stanfordgibsonIf you have guest recommendations or feedback you can reach out to me on LinkedIn or ResearchGate or fill out this recommendation and feedback form: https://forms.gle/wWJLVSEYe7S8Cd248

Radio El Respeto
Ciencia Fascinante- Episodio 3

Radio El Respeto

Play Episode Listen Later Jun 7, 2026 79:55


Una momificación de hace 14.000 años que sigue practicándose hoy en una aldea de Indonesia. El ARN de una cría de mamut congelada 50.000 años, rescatado cuando era imposible. La cara real de los europeos de hace 10.000 años. Y una roca en Marte con manchas de leopardo que puede ser la señal de vida más importante de la historia. Cuatro cartas que el tiempo no pudo borrar. Esta noche, aprendemos a leerlas. Bienvenido a Ciencia Fascinante 1x03: Lo que el tiempo no pudo borrar. ▶ EN ESTE EPISODIO: El humo que venció a 14.000 años — El equipo de Hsiao-chun Hung (Universidad Nacional de Australia) publicó en PNAS en 2025 el hallazgo más impactante de la arqueología reciente: la momificación deliberada de cuerpos humanos data de hace más de 14.000 años en el sudeste asiático. Y la misma técnica —ahumar el cuerpo de los muertos durante semanas para conservarlos— sigue practicándose hoy en el pueblo Dani de Indonesia. Catorce mil años de un gesto humano idéntico. ¿Cómo sabe la ciencia que no fue accidental? La respuesta está dentro de los propios huesos. La carta que no debía sobrevivir — Yuka es una cría de mamut lanudo que murió en la estepa siberiana hace 50.000 años. Su cuerpo lleva décadas en un museo. Pero en 2025, un equipo de Estocolmo publicó en Cell algo que la biología consideraba materialmente imposible: el ARN —la molécula mensajera que activa los genes y que se destruye en horas en condiciones normales— seguía ahí. Cincuenta mil años después. Intacto. Y decía algo. ️ El rostro que olvidamos que teníamos — Guido Barbujani, genetista de la Universidad de Ferrara, reconstruyó en pantalla la cara de un europeo de hace 10.000 años a partir de su ADN. El resultado no era lo que casi nadie esperaba: piel muy oscura, ojos azul-verdosos. Y no era una excepción. Era como éramos casi todos. La cara de Europa antes de que Europa fuera lo que creemos que siempre fue. Las manchas de leopardo de Marte — El rover Perseverance se detuvo ante una roca en el cráter Jezero y encontró un patrón de manchas oscuras con halo claro, como la piel de un leopardo. El espectrómetro reveló vivianita y greigita: dos minerales que en la Tierra casi siempre los fabrica algo vivo. Un equipo de la NASA publicó en Nature en 2025 lo que ningún científico serio dice a la ligera: es la señal más clara de vida extraterrestre hallada hasta la fecha. Síguenos en Redes Twitter: https://twitter.com/radioelrespeto Instagram: https://www.instagram.com/radioelrespeto/ Facebook: https://www.facebook.com/radioelrespeto Redes Sociales del Equipo: | Pablo Fuente | https://www.instagram.com/pablofuente/ | Nacho Sevilla | https://twitter.com/nachorsevilla | Fernando Sierra | https://twitter.com/Peeweeyo1

Galaxie Pop - La Constellation
Good Morning La Galaxie du 07-06-2026

Galaxie Pop - La Constellation

Play Episode Listen Later Jun 7, 2026 50:04


Six bonnes nouvelles , six découvertes musicales , et une nouvelle rubrique tout au fond de la soute. Embarquement immédiat, Stratonautes. Une fine plaque de métal noircie au laser dessale l'eau de mer au seul soleil Université de Rochester, revue Light: Science & Applications : https://doi.org/10.1038/s41377-026-02315-4 Première mondiale : sur un mois entier, le solaire et l'éolien réunis ont produit plus d'électricité que le gaz (531 TWh contre 477). Source : think tank indépendant Ember. L'OMS valide l'élimination du trachome, première cause infectieuse de cécité au monde : 10e pays de la Région Afrique, 29e à l'échelle mondiale. Source : OMS (23 avril 2026). Reconstituer les poissons de récif pourrait augmenter les prises durables de près de 50 %, soit jusqu'à 162 millions de portions de plus par an et par pays (l'Indonésie en tête). Smithsonian (STRI), revue PNAS : https://doi.org/10.1073/pnas.2508805122 Le cheval de Przewalski, le takhi, un temps éteint à l'état sauvage, est de retour : environ 450 dans le parc de Hustai, plus d'un millier dans le pays. Source : parc national de Hustai (relayé par Global Voices). La musique enregistrée signe une 10e année de croissance (1,071 milliard d'euros, +3,9 %). Le vinyle bondit (+14,8 %), et ce sont les 15-34 ans qui l'achètent le plus. Source : SNEP, bilan 2025. DANS LA SOUTE Toy Story 5, en salles le 17 juin.Une reco à partager ? Rendez-vous sur le Discord Galaxie Pop. Générique : Wil Bolton – Quiet Sunlight Green-House – Morning Glory Waltz : https://green-house.bandcamp.com/track/morning-glory-waltz Max Cooper & Rob Clouth – Candeleda : https://maxcooper.bandcamp.com/track/candeleda-2 Sofiane Saidi & Mazalda – La Classe Fi Las Vegas : https://sofianesaidimazalda.bandcamp.com/track/la-classe-fi-las-vegas Chancha Via Circuito – Ilaló (feat. Mateo Kingman) [Baiuca Remix] : https://chanchaviacircuitomusic.bandcamp.com/track/ilal-feat-mateo-kingman-baiuca-remix Bugan Band – Mornight : https://buganband.bandcamp.com/track/4-mornight Chapelier Fou – Darling, darling, darling : https://chapelierfou.bandcamp.com/track/darling-darling-darling-2 SOUTENIR L'ÉMISSION Ko-Fi : https://ko-fi.com/strates Rendez-vous dimanche prochain, même orbite, même fréquence. Le linktr.ee de Galaxie Pop: https://linktr.ee/galaxiepopRetrouvez moi sur le discord de Galaxie Pop : https://discord.gg/ryvkUTM

SpearFactor Spearfishing Podcast
Spearfactor #81: Dr Ray Hilborn, MPAs & Fisheries Science

SpearFactor Spearfishing Podcast

Play Episode Listen Later Jun 4, 2026 79:08


In this episode of the SpearFactor Podcast, I talk with Dr. Ray Hilborn, a fisheries scientist at the University of Washington, about the state of fisheries worldwide and the real-world data behind marine conservation. Ray has spent decades studying fish populations, fishing fleets, and management systems across the globe. He walks me through what his research shows about which fisheries are healthy, which are in trouble, and what separates the two. Many of the assumptions people hold about overfishing don't match the data, and Ray explains where the gap comes from. We also get into marine protected areas. MPAs are often presented as the default tool for ocean conservation, but Ray argues the picture is more complicated. We talk about where MPAs help, where they fall short, what they cost in terms of food production and displaced fishing effort, and why catch limits, gear rules, and stock assessments often do more for fish populations than closing off areas of the ocean. Ray explains that the best way to manage fisheries is not through MPAs, but through active fisheries management and enforcement — science-based catch limits, gear restrictions, stock assessments, and monitoring. He points to his own research showing that where fisheries are managed and enforced, stocks are at target levels or rebuilding, and where management is weak, stocks decline. Papers referenced in the episode: Hilborn, R. et al. (2020). Effective fisheries management instrumental in improving fish stock status. PNAS 117(4): 2218–2224. Hilborn, R. (2016). Policy: Marine biodiversity needs more than protection. Nature 535: 224–226. Hilborn, R. (2013). Environmental cost of conservation victories. PNAS 110(23): 9187. Hilborn, R. & Kaiser, M.J. (2021). Critique of Sala et al., Protecting the global ocean for biodiversity, food and climate, Nature (which was subsequently corrected). Hilborn, R. (2021). Increasing fisheries harvest with MPAs: Leaving South and Southeast Asia behind. PNAS — reply on Cabral et al. Topics covered: The state of global fisheries based on actual stock data Common myths about overfishing and where they come from How fisheries are managed in the U.S. and abroad Marine protected areas: where they work and where they don't Trade-offs between MPAs, food supply, and displaced fishing effort Why active fisheries management and enforcement outperform area closures Sources: Effective fisheries management instrumental in improving fish stock status — PNAS Policy: Marine biodiversity needs more than protection — Nature Environmental cost of conservation victories — PNAS Critique of Sala et al. 2021 — Sustainable Fisheries UW Increasing fisheries harvest with MPAs: Leaving South and Southeast Asia behind — PNAS Learn more about your ad choices. Visit megaphone.fm/adchoices

PNAS Science Sessions
Brain function after cryopreservation

PNAS Science Sessions

Play Episode Listen Later Jun 1, 2026 10:33


Cryopreservation of brain tissue structures Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Alexander German explains how to cryopreserve brain tissue through vitrification. In this episode, we cover: •[00:00] Introduction. •[01:14] Physician-scientist Alexander German introduces the problems with traditional cryopreservation methods. •[02:22] German explains why we cryopreserve tissue. •[03:23] He tells about vitrification and why it's different than traditional cryopreservation. •[04:13] German explains why osmotic stress is a concern in cryopreservation. •[04:51] He talks about how the protocol minimizes damage to brain structures and tissues. •[06:26] He recounts the tests they performed to evaluate the preservation and function of the vitrified tissues. •[07:03] German describes the usefulness of vitrification. •[08:48] He lists the caveats and limitations of the study. •[10:03] Conclusion. About Our Guest: Alexander German  Resident Universität Erlangen-Nürnberg View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2516848123 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Ethan 紳士流
有沒有一種愛,是永遠不會消失的?|為什麼你越被愛,越沒有安全感

Ethan 紳士流

Play Episode Listen Later May 29, 2026 28:28


這集的音質有些不穩定,因為麥克風臨時出了點狀況,聽起來可能會有點吃力,請你多多包涵,下一集會格外注意。這一集,我想陪你問一個你可能放在心裡很久的問題:有沒有一種愛,是永遠不會消失的?我們會用一千八百年前的龍樹菩薩、四百年前的笛卡兒,還有當代物理學家 Carlo Rovelli 的見證,一起把「愛」這個你以為你很熟、其實從來沒有真正看清楚的東西,看到底。

Immune
Immune 104: All about allergies

Immune

Play Episode Listen Later May 26, 2026 80:32


The Immune team talks about two papers on the effect of sleep and environment on seasonal allergies.  Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Sleep is needed for condition dependent allergic responses (PNAS, 2020) Original paper on allergy to artificial rose (Am. J. Med. Sci. 181, 45–56 (1886)) One of multiple personalities allergic (Am J Clin Hypn, 1983) Environmentally driven immune imprinting protects against allergy (Nature, 2026) News and Views on immune imprinting paper (Nature, 2026) Immune 90 discussion of "dirty mice" Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Human Centered
Network Science's Chief Economist

Human Centered

Play Episode Listen Later May 22, 2026 57:58


Matthew O. Jackson is perhaps the world's most renowned scholar of the economics of networks; as a 2005-06 CASBS fellow, he wrote most of his still-influential book Social and Economic Networks. In this wide-ranging conversation with 2025-26 CASBS fellow Rajiv Sethi, Jackson discusses his foundational work on strategic modeling of networks, empirical applications on the role of economic connectedness in influencing people's life trajectories in the U.S., related multi-disciplinary and cross-national work he is undertaking at the Santa Fe Institute, and recent cutting-edge work using large language models to gain insights into human motivations and behaviors. Matthew O. Jackson: Stanford faculty page | Personal website | CASBS page | Wikipedia page | Google Scholar page | National Academy of Sciences bio | Stanford profile | SFI page | NBER working papers | Jackson CV | Rajiv Sethi: Barnard faculty page | Columbia page | CASBS page | Google Scholar page | SFI page | Rajiv's Substack newsletter, Imperfect Information |  Matt Jackson works referenced in this episode: Matthew Jackson and Asher Wolinsky, "A Strategic Model of Social and Economic Networks," Journal of Economic Theory (1996) Matthew Jackson and Alison Watts, "The Evolution of Social and Economic Networks," Journal of Economic Theory (2002) Raj Chetty, Matthew Jackson, et al., "Social Capital I: Measurement and Associations with Economic Mobiliity," Nature (2022) Raj Chetty, Matthew Jackson, et al., "Social Capital II: Determinants of Economic Connectedness," Nature (2022) Chetty, Jackson, et al., Opportunity Insights Social Capital Atlas (website)Dynamics of Wealth Inequality project (Santa Fe Institute) Matthew Jackson, Social and Economic Networks, Princeton University Press (2008) Matthew Jackson, The Human Network, Penguin Random House (2020) Mei, Yuan, and Jackson, "A Turing Test of Whether AI Chatbots are Behaviorally Similar to Humans," PNAS (2024) Xie, Mei, Yuan, and Jackson, "Using Large Language Models to Categorize Strategic Situations and Decipher Motivations Behind Human Behaviors," PNAS (2025) --- Rajiv Sethi's latest op-ed is "Polymarket Anonymity Must End," Financial Times (May 7, 2026) Subscribe to Rajiv's Substack newsletter, Imperfect Information   Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford UniversityExplore CASBS: website | Bluesky | X | YouTube |LinkedIn | podcast |latest newsletter | signup | outreach​Human CenteredProducer: Mike Gaetani | Audio engineer & co-producer: Joe Monzel |

Biologia em Meia Hora
Humanos ainda evoluem?

Biologia em Meia Hora

Play Episode Listen Later May 22, 2026 26:55


A evolução humana acabou? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, como dois estudos mostraram que os seres humanos continuam evoluindo, desde populações adaptadas à falta de oxigênio em grandes altitudes até grupos que desenvolveram maior tolerância a água naturalmente contaminada por arsênio.Apresentação: Mila Massuda (@milamassuda)Roteiro: Mila Massuda (@milamassuda)Técnico de Gravação: Julianna Harsche (@juvisharsche) e Caio de Santis (@caiodesantis)Editora: Angélica Peixoto (@angewlique)Mixagem e Masterização: Caio de Santis (@caiodesantis)Produção: Emilio Garcia (@emilioblablalogia), Caio de Santis (@caiodesantis), Matheus Herédia (@Matheus_Heredia), Prof. Vítor Soares (@profvitorsoares), BláBláLogia Produções (@blablalogia) e Biologia em Meia Hora (@biologiaemmeiahora)Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivros)ReferênciasYE, S. et al. Higher oxygen content and transport characterize high-altitude ethnic Tibetan women with the highest lifetime reproductive success. PNAS, v. 121, n. 45, e2403309121, 2024.SCHLEBUSCH, C. M. et al. Human adaptation to arsenic-rich environments. Molecular Biology and Evolution, v. 32, n. 6, p. 1544–1555, 2015.

Fundação (FFMS) - [IN] Pertinente
SOCIEDADE | Trabalho e ensino na era da IA

Fundação (FFMS) - [IN] Pertinente

Play Episode Listen Later May 21, 2026 46:42


Quais são as profissões mais ameaçadas pela inteligência artificial? E de que forma a IA pode transformar o ensino? Bernardo Caldas e Hugo van der Ding analisam os sinais da automação no mercado de trabalho e na educação das gerações futuras.Nos últimos três anos, as vagas para juniores em áreas mais expostas à IA caíram 30% a 40%, à medida que tarefas repetitivas, analíticas e administrativas são substituídas por algoritmos. Mas estarão apenas os empregos menos qualificados em risco?Neste episódio, o especialista em IA e o comunicador observam que também as profissões altamente especializadas estão ameaçadas – a começar, ironicamente, pelos engenheiros tecnológicos, mas atingindo, igualmente, advogados, consultores e médicos, sobretudo em especialidades de diagnóstico.Mas nem tudo são más notícias: numa época em que o desemprego se mantém em níveis historicamente baixos, a IA também pode ter impactos positivos na educação, ao democratizar o acesso à informação entre diferentes estratos sociais.A dupla discute ainda os desafios e oportunidades desta revolução — e porque é que o pensamento crítico, uma visão integrada do mundo e a «motivação intrínseca» serão competências decisivas no futuro.Para acompanhar a velocidade das transformações em curso, não perca este episódio do [IN]Pertinente.LINKS E REFERÊNCIAS ÚTEISBASTANI et al., «Generative AI without guardrails can harm learning: Evidence from high school mathematics», (PNAS 122(26), 2025)BRYNJOLFSSON, CHANDAR & CHEN, «Canaries in the Coal Mine?» (Stanford Digital Economy Lab, 2025)DELL'ACQUA, MOLLICK et al., «Navigating the Jagged Technological Frontier» (Harvard/BCG, 2023)KESTIN et al., «AI tutoring outperforms in-class active learning: an RCT», (Scientific Reports, 2025)DE SIMONE et al., «From Chalkboards to Chatbots: Evaluating the Impact of Generative AI on Learning Outcomes in Nigeria», (World Bank WPS 11125, 2025)ACEMOGLU, Autor & JOHNSON, «The Direction of AI», (NBER WP 34854, 2026)GARICANO-RAYO, «AI and the Expertise Leverage Ratio», (CEPR DP 20634, 9/9, 2025)LEE et al. (Microsoft + CMU), «The Impact of Generative AI on Critical Thinking», (CHI 2025)CAPLAN, «The Case Against Education» (Princeton UP, 2018)BJORK & BJORK, «Making things hard on yourself, but in a good way», (Gernsbacher et al., Psychology and the Real World, 2011)RYAN & DECI, «Self-Determination Theory», (American Psychologist, 2000)RISKO & GILBERT, «Cognitive offloading», (Trends in Cognitive Sciences, 2016)MOLLICK & MOLLICK, «Assigning AI: Seven Approaches for Students, with Prompts», (SSRN 4475995, 2023)BIOSBernardo CaldasEspecialista em inteligência artificial e cofundador da associação «Data Science for Social Good Portugal», uma associação que desenvolve projetos de ciência de dados e inteligência artificial com impacto social positivo.Hugo van der Ding Locutor, criativo e desenhador acidental. Criador de personagens digitais de sucesso como a «Criada Malcriada» e «Cavaca a Presidenta», autor de um dos podcasts mais ouvidos em Portugal, «Vamos Todos Morrer», também escreve para teatro e, atualmente, apresenta o programa «Duas Pessoas a Fazer Televisão», na RTP, com Martim Sousa Tavares. 

PNAS Science Sessions
Paleoecology of Doggerland

PNAS Science Sessions

Play Episode Listen Later May 18, 2026 10:39


The lost forests of Doggerland Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Robin Allaby explores the paleoecology of the submerged area known as Doggerland. In this episode, we cover: •[00:00] Introduction. •[01:10] Evolutionary biologist Robin Allaby introduces the location of Doggerland and history of its exploration. •[02:58] He introduces sedimentary DNA, including how it can be used to reconstruct paleoecology. •[03:43] Allaby describes the methods of the study. •[05:18] He introduces the primary findings about the plant and animal life of Doggerland. •[06:14] He describes the surprising find of Pterocarya in Doggerland.  •[08:07] Allaby discusses the habitability of Doggerland for Mesolithic societies. •[09:38] He lists the caveats and limitations of the study. •[10:13] Conclusion. About Our Guest: Robin Allaby  Professor University of Warwick View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2508402123 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

More than Money Podcast
FINANCIAL BIOHACKING - Wie dein Körper deine Finanzen sabotiert – und was du darüber garantiert noch nicht wusstest (Folge 293)

More than Money Podcast

Play Episode Listen Later May 18, 2026 20:41


5 Ebenen: Besser denken, sprechen, handeln, entspannen, fühlen. 5 Hacks. Wissenschaftlich belegt. Und ab heute anwendbar – wenn du weißt wie. Financial Biohacking. Ein Begriff, den du so noch nirgendwo gehört hast. Weil Andreas ihn frisch geprägt hat. Weil es Zeit wurde. Nico Airone hat mit seinem Men's Health Buch über Biohacking gezeigt, wie körperliche Selbstoptimierung die Gesundheit fördert. Höre hier, warum Andreas dieses Prinzip auf deine Beziehung zu Geld überträgt. Denn die Forschung zeigt: Viele Geldblockaden sitzen im Nervensystem. Hör' jetzt direkt rein.➡️ Du möchtest dein Money Mindset richtig einstellen? Dann sichere dir hier ein kostenloses Erstgespräch

Psychologie to go!
Mythos Midlife Crisis? Was wirklich dahinter steckt

Psychologie to go!

Play Episode Listen Later May 17, 2026 46:26 Transcription Available


Midlife-Crisis: Ein 50 jähriger Mann, der jetzt eine Harley kauft. Ist das nur ein Klischee oder ist da was dran? Gibt es echte Krisen in der Mitte des Lebens? Franca und Christian nehmen eines der bekannteste Konzepte der Alltagspsychologie auseinander. Das Gehirn beginnt sich ab Mitte 40 messbar, aber leise umzubauen. In dieser Folge geht es um den Unterschied zwischen kulturellem Skript und echter Biologie, über das, was Frauen in der Perimenopause wirklich erleben, und darüber, was die Forschung als das eigentliche Merkmal gesunden Alterns beschreibt. Quellen: Blanchflower DG, Bryson A, Xu X (2025): The declining mental health of the young and the global disappearance of the unhappiness hump shape in age. DOI: 10.1371/journal.pone.0327858 Schmidt S (2020): Midlife Crisis: The Feminist Origins of a Chauvinist Cliché. University of Chicago Press. DOI: 10.7208/9780226686998 Mujica-Parodi LR et al. (2025): Brain aging shows nonlinear transitions, suggesting a midlife ‘critical window' for metabolic intervention. PNAS. DOI: 10.1073/pnas.2416433122 Bromberger JT et al. (2011): Major depression during and after the menopausal transition: SWAN. Psychological Medicine. PMID: 21306662 Francas SISU- Kurssi gibt es zwischen dem 17.Mai und dem 2. Juni günstiger: www.sisu-online.de Francas neues Buch: Die innere Oma — ab 4. September 2026, jetzt vorbestellbar: https://shop.autorenwelt.de/products/die-innere-oma-von-franca-cerutti Alle Tourdaten und Tickets: https://www.190a.de/psychologie-to-go/ Du möchtest mehr über unsere Werbepartner erfahren? Hier findest du alle Infos & Rabatte: https://linktr.ee/psychologietogo Du möchtest Werbung in diesem Podcast schalten? Dann erfahre hier mehr über die Werbemöglichkeiten bei Seven.One Audio: https://www.seven.one/portfolio/sevenone-audio

The Swerve Podcast
DMT Laser Experiment: Simulation-maxxing

The Swerve Podcast

Play Episode Listen Later May 13, 2026 88:14


Is the DMT laser experiment proof we are in a simulation? Strangers see the same alien glyphs, the code of reality. Neuroscience explains it. Almost...Is the "Code of Reality" a genuine window into a computed simulation, or merely an artifact of our brain's architecture?I deep dive into the DMT laser experiment, a $15 protocol that allegedly reveals hidden source code of our universe. I investigate why strangers independently report the same bizarre characters and geometric structures, and whether this "shared reality" unveils the Matrix or is simply a trick of our visual cortex.Topics (among others):The Code of Reality: How Danny Goler's repeatable experiment uses a 650nm red laser and DMT to induce perceptions of a high-definition hyper-structure of code.The 40,000-Year Trail: Why Paleolithic cave art, UFO glyphs, and Soviet Kozyrev Mirror experiments all feature similar geometric codes/glyphs long before the modern simulation hypothesis interpretations.Neuroscience vs. Simulation: How the Bressloff-Cowan V1 Model provides a mathematical model for why our natural brain wiring produces similar "form constants" with hallucinogens.Consider Supporting + Receive Bonus Content⁠

Update Erde - Deutschlandfunk Nova
Kriege - Warum der Klimawandel das größte Sicherheitsrisiko ist

Update Erde - Deutschlandfunk Nova

Play Episode Listen Later May 13, 2026 17:30


Eine neue Studie zeigt, wie Extremwetter-Ereignisse Konflikte befeuern. Wir erklären, warum Geheimdienste im Klimawandel die größte Gefahr für die weltweite Sicherheit sehen. Und wir begleiten vietnamesische Fasane auf dem Weg in ihre Heimat. **********In dieser Folge:0:00 - Die Rolle von El Niño4:55 - Wie der Klimawandel Konflikte verschärft7:48 - Warum die Klimakrise die größte Gefahr für die nationale Sicherheit ist10:31 - Wie der Irankrieg die Energiewende vorantreibt13:42 - Was geht: Vietnamesische Fasane kehren zurück in ihre Heimat15:54 - Deine Minute Natur: Bach im Schwarzwald**********Ihr hört: Moderation: Klaus Jansen und Matthias Wurms**********Weiterführende Quellen zu dieser Folge:Studie in PNAS zum Zusammenhang zwischen Klimaphänomenen und KonfliktenNationale Klimarisiko-Einschätzung im Auftrag der BundesregierungStudie zu den historischen Folgen von KlimaschwankungenUpdate-Erde-Folge zu den Umweltfolgen von KriegenUpdate-Erde-Folge zu ZoosAlle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Ihr habt Anregungen, Ideen, Themenwünsche? Dann schreibt uns gern unter updateerde@deutschlandfunknova.de.

Choses à Savoir SCIENCES
Pourquoi naît-il de moins en moins de garçons ?

Choses à Savoir SCIENCES

Play Episode Listen Later May 12, 2026 2:12


Depuis toujours, il naît légèrement plus de garçons que de filles chez les êtres humains. En moyenne, pour 100 filles, environ 105 garçons viennent au monde. Cette différence compense le fait que les garçons sont biologiquement un peu plus fragiles durant l'enfance.Mais aujourd'hui, certains chercheurs observent un phénomène troublant : dans plusieurs régions du monde, cette proportion semble diminuer.Et une étude publiée dans la revue scientifique PNAS suggère que le réchauffement climatique pourrait jouer un rôle inattendu dans cette évolution.Les chercheurs de l'Université d'Oxford ont analysé plus de cinq millions de naissances sur plusieurs décennies. Leur objectif : comprendre comment les températures influencent le sexe des bébés à la naissance.Le résultat est frappant.Lorsque les températures dépassent environ 20 °C pendant des périodes prolongées, la proportion de garçons diminue significativement.Autrement dit : plus il fait chaud, moins il naît de garçons.Mais pourquoi ?La clé se trouve probablement dans la fragilité biologique des fœtus masculins.Dès les premières semaines de grossesse, les embryons mâles semblent plus vulnérables aux stress environnementaux : pollution, malnutrition, catastrophes naturelles… et désormais chaleur extrême. Les scientifiques pensent que le stress thermique pourrait augmenter les risques de fausses couches spontanées touchant davantage les fœtus masculins.Car porter un enfant représente déjà un immense effort physiologique pour l'organisme maternel. Or la chaleur ajoute un stress supplémentaire : déshydratation, inflammation, perturbation hormonale, augmentation du cortisol — l'hormone du stress.Et les embryons masculins résisteraient moins bien à ces conditions difficiles.Ce phénomène avait déjà été observé après certains événements extrêmes. Après des canicules, des famines ou des catastrophes naturelles, plusieurs pays avaient enregistré temporairement moins de naissances masculines.Mais l'étude d'Oxford est l'une des plus vastes jamais réalisées sur le sujet, et elle renforce l'idée que le climat pourrait influencer directement la composition démographique humaine.Attention toutefois : il ne s'agit pas d'une disparition massive des garçons. Le phénomène reste modéré. Mais à l'échelle de populations entières et sur plusieurs décennies, ces variations deviennent statistiquement très importantes.Les chercheurs soulignent aussi qu'il pourrait exister d'autres facteurs liés au réchauffement climatique : pollution atmosphérique accrue, perturbateurs endocriniens ou modification des conditions de vie.Cette découverte rappelle surtout une chose fascinante : le changement climatique n'affecte pas seulement les glaciers, les océans ou les forêts.Il pourrait aussi agir silencieusement sur la biologie humaine elle-même.Jusqu'à influencer, peut-être, le sexe des enfants qui naîtront demain. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Choses à Savoir TECH VERTE
Déforestation : l'ONU propose un outil efficace ?

Choses à Savoir TECH VERTE

Play Episode Listen Later May 10, 2026 2:20


La déforestation n'est pas seulement une question environnementale, c'est aussi un enjeu climatique majeur. Selon les estimations du budget carbone mondial, liées aux travaux des Nations unies, les changements d'usage des terres, comme la transformation de forêts en zones agricoles, représentent entre 10 et 15 % des émissions mondiales de CO₂.Le problème est double. D'un côté, la déforestation libère du carbone stocké dans les arbres. De l'autre, elle détruit ce que l'on appelle des « puits de carbone » : des écosystèmes capables d'absorber et de stocker le dioxyde de carbone présent dans l'atmosphère. Résultat : moins d'absorption, plus d'émissions. Pour tenter d'enrayer ce phénomène, un mécanisme international a été mis en place : le programme REDD+, pour « Réduction des émissions dues à la déforestation et à la dégradation des forêts ». Lancé en 2007 dans les négociations climatiques, puis intégré à l'Accord de Paris, il repose sur une idée simple : inciter financièrement les pays, notamment en développement, à préserver leurs forêts.Concrètement, les efforts de réduction de la déforestation peuvent être convertis en « crédits carbone ». Ces crédits sont ensuite vendus à des États ou des entreprises, qui les utilisent pour compenser une partie de leurs émissions. Il s'agit donc d'un mécanisme de marché, où la protection des forêts devient une ressource économique. Une version plus récente, appelée REDD+ juridictionnel, applique ce système à l'échelle d'un pays ou d'une région entière. Mais ce modèle soulève des interrogations. Des chercheurs de l'Université Yale, dans une étude publiée dans la revue PNAS, pointent plusieurs limites.Selon eux, le dispositif peut encourager des comportements stratégiques. Certains États pourraient être récompensés pour des réductions de déforestation qui auraient eu lieu de toute façon, sans véritable effort supplémentaire. Une situation qui fausse le système et réduit son efficacité réelle. Les chercheurs recommandent donc d'améliorer les méthodes de calcul des niveaux de référence, c'est-à-dire les estimations de déforestation attendue, ainsi que les systèmes de mesure et de vérification. L'objectif : s'assurer que chaque crédit carbone correspond bien à une réduction réelle des émissions. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

TheOccultRejects
The Rhythms of Consciousness: Delta, Theta, Alpha, Beta, and Gamma

TheOccultRejects

Play Episode Listen Later May 8, 2026 65:07 Transcription Available


If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects.  In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge.  So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below.  Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejects1. Patel, A. K., et al. *Physiology, Sleep Stages*. StatPearls / NCBI Bookshelf, 2024.2. Jensen, O., & Mazaheri, A. “Shaping Functional Architecture by Oscillatory Alpha Activity: Gating by Inhibition.” *Frontiers in Human Neuroscience*, 2010.3. Cavanagh, J. F., & Shackman, A. J. “Frontal Midline Theta Reflects Anxiety and Cognitive Control: Meta-Analytic Evidence.” *Journal of Physiology-Paris*, 2015.4. Axmacher, N., et al. “Cross-Frequency Coupling Supports Multi-Item Working Memory in the Human Hippocampus.” *PNAS*, 2010.5. Lacaux, C., et al. “Sleep Onset Is a Creative Sweet Spot.” *Science Advances*, 2021.6. Horowitz, A. H., et al. “Targeted Dream Incubation at Sleep Onset Increases Post-Sleep Creative Performance.” *Scientific Reports*, 2023.7. Caporro, M., et al. “Functional MRI of Sleep Spindles and K-Complexes.” *Clinical Neurophysiology*, 2012.8. Ng, T., et al. “Bayesian Meta-Analysis Reveals the Mechanistic Role of Slow Oscillation-Spindle Coupling in Sleep-Dependent Memory Consolidation.” *eLife*, 2025.9. Datta, K., et al. “Electrophysiological Evidence of Local Sleep During Yoga Nidra Practice in Young Male Volunteers.” *Frontiers in Neurology*, 2022.10. Jensen, M. P., et al. “Brain Oscillations, Hypnosis, and Hypnotizability.” *American Journal of Clinical Hypnosis*, 2015.11. Huels, E. R., et al. “Neural Correlates of the Shamanic State of Consciousness.” *Frontiers in Human Neuroscience*, 2021.12. Ingendoh, R. M., et al. “Binaural Beats to Entrain the Brain? A Systematic Review...” *PLOS ONE*, 2023.13. Páez, A., et al. “Sleep Spindles and Slow Oscillations Predict Cognition and Biomarkers of Neurodegeneration in Mild to Moderate Alzheimer's Disease.” *Alzheimer's & Dementia*, 2025.14. Askitopoulou, H. “Sleep and Dreams: From Myth to Medicine in Ancient Greece.” *Journal of Anesthesia History*, 2015.15. Pavli, A. “Asclepieia in Ancient Greece: Pilgrimage and Healing.” *Journal of Integrative Medicine and Research*, 2024.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. Now let me introduce the rest of the panel and guests.

Scaling Theory
#30 – Matthew O. Jackson on How Networks Quietly Shape What You Believe

Scaling Theory

Play Episode Listen Later May 6, 2026 47:38


Welcome back to Scaling Theory. In this episode, I speak with Matthew O. Jackson, the William D. Eberle Professor of Economics at Stanford University and an external faculty member at the Santa Fe Institute. Matthew is one of the founders of the modern economics of networks and the author of The Human Network and Social and Economic Networks.We talk about the friendship paradox, why homophily slows how fast a society learns the truth but helps niche ideas catch fire, and the gossip study where villagers in southern India proved remarkably good at naming the most central spreaders in their community. We then turn to AI agents as a different species: Turing tests on LLMs, the steerability of agent personas through system prompts, and what to make of Moltbook, the social network for AI agents.By the end, you will know why telling students how much their peers actually drink reduces binge drinking more than warning them about the dangers of alcohol, why the same network can spread a virus quickly and a belief slowly, and why AI agents change their behavior when asked to explain it.Papers and works referenced in the conversationBooksThe Human Network: How Your Social Position Determines Your Power, Beliefs, and Behaviors — Matthew O. Jackson (Pantheon, 2019). https://web.stanford.edu/~jacksonm/books.htmlSocial and Economic Networks — Matthew O. Jackson (Princeton University Press, 2008). https://web.stanford.edu/~jacksonm/books.htmlPart I — The scaling of human networks"Diffusion and Contagion in Networks with Heterogeneous Agents and Homophily" — Matthew O. Jackson and Dunia López-Pintado, Network Science 1(1), 2013. https://arxiv.org/abs/1111.0073"How Homophily Affects the Speed of Learning and Best-Response Dynamics" — Benjamin Golub and Matthew O. Jackson, Quarterly Journal of Economics 127(3), 2012. https://web.stanford.edu/~jacksonm/homophily.pdf"Using Gossips to Spread Information: Theory and Evidence from Two Randomized Controlled Trials" — Abhijit Banerjee, Arun G. Chandrasekhar, Esther Duflo, and Matthew O. Jackson, Review of Economic Studies 86(6), 2019. https://academic.oup.com/restud/article/86/6/2453/5345571"Empathy and Well-Being Correlate with Centrality in Different Social Networks" — Sylvia A. Morelli, Desmond C. Ong, Rucha Makati, Matthew O. Jackson, and Jamil Zaki, PNAS 114(37), 2017. https://www.pnas.org/doi/10.1073/pnas.1702155114Part II — The scaling of AI agents"Inequality's Economic and Social Roots: The Role of Social Networks and Homophily" — Matthew O. Jackson, in Advances in Economics and Econometrics: Twelfth World Congress of the Econometric Society (Cambridge University Press, 2025). https://arxiv.org/abs/2506.13016"AI Behavioral Science" — Jackson, Mei, Wang, Xie, Yuan, Benzell, Brynjolfsson, Camerer, Evans, Jabarian, Kleinberg, Meng, Mullainathan, Ozdaglar, Pfeiffer, Tennenholtz, Willer, Yang, and Ye, arXiv 2509.13323, 2025. https://arxiv.org/abs/2509.13323"A Turing Test of Whether AI Chatbots Are Behaviorally Similar to Humans" — Qiaozhu Mei, Yutong Xie, Walter Yuan, and Matthew O. Jackson, PNAS 121(9), 2024. https://www.pnas.org/doi/10.1073/pnas.2313925121

Lass' uns leuchten.
Wenn Zufälle plötzlich mystisch oder magisch werden

Lass' uns leuchten.

Play Episode Listen Later May 6, 2026 19:15


Zufälle können eine ganz besondere Ebene bekommen ✨.Wenn Überschneidungen des inneren und äußeren Erlebens sich in keinen kausalen Zusammenhang bringen lassen, für uns selbst jedoch einen bedeutungsvollen Moment auslösen, spricht man von Synchronizitäten.Diese Synchronizitäten haben nach meiner Erfahrung ganz individuelle Botschaften für uns im Gepäck. Und warum die Freude und das Vertrauen zu Verstärkern solcher Erfahrungen werden können, auch darüber spreche ich in dieser Folge.Ich schicke Glitterstaub zu dir, denn:Auch du machst die Welt heller ⭐️!Alles Liebe,YvonneLink zur Folge:(zuletzt eingesehen am 05.05.2026)Hier findest du die Studie zur 'Bodiliy maps of emotions' der PNAS:https://www.pnas.org/doi/10.1073/pnas.1321664111In eigener Sache ❣️Hier im Podcast und auf meinem YouTube-Kanal⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @auchdumachstdieweltheller ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠erscheinen regelmäßig Solofolgen und auch Gespräche mit ganz unterschiedlichen Menschen, die den Alltag anderer ein Stück heller machen. Und für inspirierendes zwischendurch folge mir doch einfach auch auf Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/yvonnemuellerbuergel/?hl=d⁠⁠⁠⁠⁠

PNAS Science Sessions
AI in scholarly publishing

PNAS Science Sessions

Play Episode Listen Later May 4, 2026 10:37


Generative AI and scientific journals Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Yi Bu explores how generative AI has changed academic publishing. In this episode, we cover: •[00:00] Introduction. •[00:50] Computational social scientist Yi Bu tells about the policies academic journals have introduced to address generative AI. •[02:17] Bu describes the dataset he analyzed and his findings regarding journals' policies. •[04:07] He answers the question: Did journal policies have any effect on AI usage? •[05:39] Bu talks about how the rate of AI disclosure compares with estimates of probable AI use. •[06:53] He explains the takeaway for journal editors and the scientific community at large. •[07:27] He lists the caveats and limitations of the study. •[10:11] Conclusion. About Our Guest: Yi Bu Assistant Professor Peking University View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2526734123 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

More Morgellons
Moving Hair and Other Technical Difficulties

More Morgellons

Play Episode Listen Later May 1, 2026 32:10


Crystal investigates an anomaly in Google search data that predicted neural interface technology disclosures by two years.What We Cover:• Georgia Tech's peer-reviewed hair follicle sensor research (published PNAS, April 2025)• Federal contract analysis: microneedle manufacturing scale-up 2020-2025• Google Trends investigation: “moving hair” search clustering with vestigial body part queries• Geographic analysis: Aarau, Switzerland and the Interneuron consortium• Supply chain documentation: 3M, Vaxxas, Vaxess government contracts• Patent landscape: neural interface applications of microneedle technology• Charles Lieber connection: injectable mesh electronics and the i-BRAIN timelineKey Sources:        •       Proceedings of the National Academy of Sciences        •       US Patent Database        •       Federal procurement records (USAspending.gov)        •       Google Trends data analysis        •       Peer-reviewed neurotechnology literature#neurotechnology #supplychainanalysis #biomedicalengineering #searchtrends #microneedleresearch #georgatech #swissresearch #patentanalysis #governmentcontracts #datatechnology Reach out to share your story:moremorgellons.com

The Field Guides
Ep. 80 - The Deer Are NOT Alright: Chronic Wasting Disease

The Field Guides

Play Episode Listen Later Apr 30, 2026


Something's not right in the woods, at least if you're a white-tailed deer. In this episode, the guys dig into chronic wasting disease (CWD), a strange illness reshaping deer populations in many areas of the Lower 48 (and Scandinavia!). It's not caused by a virus or a bacteria, but it is related to mad cow disease. They break down what it is, how it spreads, what's happening inside infected animals, and why it's so dang hard to contain. The deer are not alright… and there's a reason.This episode was recorded on April 23, 2026 at Walton Woods Park in Amherst, NY (a suburb of Buffalo). Episode Notes and Links· Are there different CWD strains in a single animal? Chronic wasting disease isn't a single, uniform pathogen. It's more like a shifting swarm. Infected deer can carry multiple prion “strains” at once, meaning different misfolded shapes of the same protein that behave in slightly different ways. They could spread through the body differently, build up in different tissues, and cause disease at different rates. Lab experiments show this most clearly: when CWD prions are passed through model systems, what looks like one strain can split into multiple distinct variants, or reveal that a mixed population was there all along (e.g., Angers et al. 2010 PNAS; Béringue et al. 2012 Journal of Virology; Li et al. 2010 Journal of Virology). In actual deer, the picture is harder to pin down, but studies comparing prions from different tissues and individuals show real strain diversity and suggest that more than one strain can exist within a single animal (e.g., Angers et al. 2009 Journal of Virology; Moore et al. 2016 Emerging Infectious Diseases). The takeaway is that CWD behaves less like a single disease agent and more like a moving target: a cloud of protein shapes, some dominant, some hidden in the background, that can shift over time, giving the disease more chances to adapt, persist, and potentially jump into new hosts.· Does repeated exposure to CWD reduce incubation time in deer? Repeated exposure to CWD prions does likely shortens incubation time, mainly because prion diseases are strongly dose-dependent. Higher cumulative exposure, whether from a single large dose or many smaller ones over time, can both increase the chance of infection and accelerate disease progression. Experimental studies in deer and elk show that animals exposed to higher or repeated doses tend to develop symptoms faster than those exposed once at low levels. In the wild, this likely plays out through repeated contact with contaminated environments like soil, plants, and carcass sites. That said, factors like genetics and prion strain can still influence how quickly the disease develops in any given animal.· Is CWD the only prion disease that affects wildlife? CWD is the only prion disease currently thriving as a self-sustaining epidemic in wild populations. The others mostly sit at the edges and are livestock diseases that occasionally spill into wildlife or appear in captive/wild interface cases. For example, scrapie occasionally “leaks” into the wild (it has been found in bighorn sheep), but it doesn't take over. It flickers at the edges of livestock systems. Nothing like the landscape-level, self-sustaining spread we see with CWD. That's what makes CWD so concerning: it's not just present in wildlife, it seems to be built for it.· Steve talked about the possibility of vampire bats and wild hogs spreading CWD. What's the story? There's currently no evidence that vampire bats are spreading CWD, but the wild hog story has gotten more interesting recently. Blood-feeding bats like the Common Vampire Bat (Desmodus rotundus) are often mentioned because prions can occur in blood at low levels, but there are no peer-reviewed studies showing bat-mediated transmission, nor any field patterns linking bats to CWD spread. So the bat idea remains speculative. Wild hogs (Sus scrofa), on the other hand, have moved beyond pure theory. A recent peer-reviewed study (e.g., Soto et al. 2025 Emerging Infectious Diseases) detected low levels of CWD prion activity in free-ranging pigs in endemic areas, suggesting they can pick up and carry prions after scavenging infected carcasses. Combine this with earlier work showing prions can survive digestion and still remain infectious (e.g., Nichols et al. 2009 PLoS ONE), it all points to hogs as plausible mechanical vectors: in other words, organisms that can move infectious material without necessarily developing the disease themselves. The takeaway: vampire bats are still a biologically interesting but unsupported idea, while wild hogs are emerging as potential “messy middlemen,” capable of redistributing prions across the landscape, even if they're not a primary engine of CWD transmission, which is still driven by deer-to-deer contact and long-lived environmental contamination.· Why doesn't NYS do more free testing?New York doesn't offer broad, free testing for every deer. Not because it's ignoring CWD, but because it uses a more targeted, strategic approach. There are a few key constraints on broad, free testing:Cost & logistics: Each test isn't just a swab. It involves lab processing (often PCR or amplification assays), trained staff, and sample handling. Scaling that to hundreds of thousands of deer is a major lift.Low prevalence (right now): When disease prevalence is near zero, mass testing tends to return very few positives, so agencies prioritize early detection in hotspots instead.Management strategy: Agencies often invest more in prevention (carcass transport rules, feeding bans, education) than broad surveillance.Hunter participation: “Free for all” testing can overwhelm systems unless tightly managed, and many states have learned that targeted programs get better data per dollar.So NYS is focusing its efforts on where they see it mattering most: high-risk areas, roadkills, sick/dead deer, and zones near known outbreaks—because testing every hunter-harvested deer statewide would be extremely expensive for relatively low yield in a state with no established CWD population.More info on NY's response, as well as what's happening nationally:The NYS Department of Environmental Conservation's page on CWD (including information on how you can help, scroll down to “Members of the Public”)CWD in Captive Deer: DEC's Response in 2024Chronic Wasting Disease Detection and Management: What Has Worked and What Has Not? A report by the CWD Alliance, a nonprofit organization focused on education, coordination, and outreach around chronic wasting disease. It was created to bring together a mix of stakeholders: state wildlife agencies, federal partners, scientists, and hunting/conservation groups to help share reliable information and improve how CWD is managed across North America. Sponsors and Ways to Support UsThank you to Always Wandering Art (Website and Etsy Shop) for providing the artwork for many of our episodes.Support us on Patreon.Works Cited Bian, J., et al. (2022). Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of chronic wasting disease. Acta Neuropathologica Communications, 10, 149.Edmunds, D. R., Kauffman, M. J., Schumaker, B. A., Lindzey, F. G., Cook, W. E., Kreeger, T. J., Grogan, R. G., & Cornish, T. E. (2016). Chronic wasting disease drives population decline of white‑tailed deer. Ecology, 97(3), 620–632.Henderson, D. M., Denkers, N. D., Hoover, C. E., Garbino, N., Mathiason, C. K., & Hoover, E. A. (2015). Longitudinal Detection of Prion Shedding in Saliva and Urine by Chronic Wasting Disease-Infected Deer by Real-Time Quaking-Induced Conversion. Journal of virology, 89(18), 9338–9347. https://doi.org/10.1128/JVI.01118-15Küry, S., et al. (2023). The zoonotic potential of chronic wasting disease—A review. Pathogens, 12(3), 342.Miller, M. W., et al. (2024). U.S. Geological Survey science strategy to address chronic wasting disease. U.S. Geological Survey Circular 1546.Monello, R. J., Powers, J. G., Hobbs, N. T., Spraker, T. R., O'Rourke, K. I., & Wild, M. A. (2014). Endemic chronic wasting disease causes mule deer population decline in Colorado. PLOS ONE, 9(10), e110353.Pirisinu, L., et al. (2024). Zoonotic potential of chronic wasting disease after adaptation in sheep. Emerging Infectious Diseases, 30(12).Sandberg, M. K., et al. (2022). Humanized transgenic mice are resistant to chronic wasting disease prions from reindeer and moose. Journal of Infectious Diseases, 226(5), 933–942.Saunders, S. E., Bartelt‑Hunt, S. L., & Bartz, J. C. (2012). Occurrence, transmission, and zoonotic potential of chronic wasting disease. Emerging Infectious Diseases, 18(3), 369–376.Visit thefieldguidespodcast.com for full episode notes, links, and works cited.

Health Longevity Secrets
EXPLAINER: Medicine's Forgotten Biomarker - The Homocysteine Story Your Doctor Missed

Health Longevity Secrets

Play Episode Listen Later Apr 30, 2026 14:09 Transcription Available


In 1969, Harvard pathologist Kilmer McCully discovered elevated homocysteine causes arterial damage and heart disease. He was forced out of Harvard. The Framingham Heart Study confirmed him. Then the AHA buried it anyway.CHAPTERS:00:00 - McCully discovery and suppression01:20 - Part 1: What homocysteine does to arteries (6 mechanisms)03:25 - Part 2: The evidence they ignored03:40 - Every 5 umol/L: 20-30% higher CAD risk, 60% stroke risk04:50 - Alzheimers risk +48% (meta-analysis, 7,474 subjects)06:10 - Part 3: Why it was abandoned (VISP, NORVIT, HOPE-2)07:50 - Cochrane: B vitamins reduced stroke 10%08:20 - CSPPT: folic acid reduced stroke 21% to 73%09:10 - Part 4: Your brain on homocysteine09:25 - VITACOG: brain atrophy 30% slower, 53% in high-Hcy group10:05 - PNAS 2013: 7x less hippocampal atrophy11:00 - Part 5: What to do11:10 - Test fasting homocysteine: target under 8-10 umol11:40 - Methylfolate, methylcobalamin, P5PREFERENCES:Homocysteine CVD Risk 2025: PMC12564181VITACOG Trial (PLoS ONE, 2010): PMC2935890VITACOG 2025 Metabolomics: PubMed 40684250Homocysteine Alzheimers Risk: PMC12280720Cochrane B Vitamins Stroke: CochraneCSPPT Folic Acid: ACCJAMA 2010 Meta-Analysis: JAMAHOST: Dr. Robert Lufkin MD | robertlufkinmd.com⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

Immune
Immune Booster 27: Interferons, JAKs, and STATs with George Stark

Immune

Play Episode Listen Later Apr 28, 2026 37:44


George Stark from the Cleveland Clinic reflects on his early training in biochemistry and how several sabbatical leaves sparked pivotal changes in his research trajectory, eventually drawing him to interferon signaling where he helped establish the core principles of the JAK–STAT pathway and uncovered interesting roles for interferon signaling in cancer. Host: Cindy Leifer Guest: George Stark Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Stark lab Development of the Northern blotting technique (PNAS, 1977) Development of Western blotting for proteins (PNAS, 1979) Discovery of Tyk2 as a critical kinase in interferon response (Cell, 1992) Topical PALA treatment for non-melanoma skin cancer (Exp Dermatol, 2023) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Outring Tinnitus Podcast
Episode 152 - Tinnitus and SSRI - What the new OSHU Study reveals

Outring Tinnitus Podcast

Play Episode Listen Later Apr 24, 2026 14:24


Hey Tinnitus Friends & Family, A new study from Oregon Health & Science University found a direct brain circuit linking serotonin to tinnitus symptoms. If you're taking antidepressants and have tinnitus, you've probably seen the headlines—and maybe felt some panic. Here's the truth: this is good science, not a reason to stop your medication. In this video, I break down what the research actually found, why mouse studies can't tell the whole story, and what this means if you're currently taking SSRIs. I also share my personal experience—I take SSRIs myself, and they haven't worsened my tinnitus. **Key Takeaways:** ✅ The study found a serotonin → auditory circuit that can create tinnitus-like behavior in mice ✅ This validates what some people report, but doesn't mean SSRIs "cause" tinnitus ✅ SSRIs can be life-changing for depression and anxiety—the benefits often far outweigh risks ✅ Never stop medication without talking to your doctor ✅ Habituation works regardless of whether you're on medication **Timestamps:** 0:00 Introduction: Who I Am (and Who I'm Not) 1:15 Why This Research Matters 2:20 What Are SSRIs? 3:40 The Study Explained: Serotonin → Auditory Circuit 5:10 How the Research Was Done (Optogenetics) 6:30 What Dr. Trussell Said About Future Treatments 7:45 My Take: What This Means for YOU 9:20 My Personal Experience with SSRIs 10:15 Bottom Line: Talk to Your Doctor 11:00 You Don't Have to Do This Alone **Resources Mentioned:**

PNAS Science Sessions
Genomic history of the Golden Horde

PNAS Science Sessions

Play Episode Listen Later Apr 20, 2026 10:21


Genomics of the Golden Horde Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Ayken Askapuli explains genomic insights into the ancestors and descendants of the Golden Horde. In this episode, we cover: •[00:00] Introduction. •[00:56] Population geneticist Ayken Askapuli introduces the Golden Horde. •[02:01] He describes the individuals in the mausoleums whose DNA the team sampled.  •[04:11] Askapuli explains findings about the modern populations the Golden Horde individuals were related to. •[05:08] He then explains findings about the Y chromosome characteristics of the Golden Horde individuals. •[06:14] Askapuli talks about what the results say about the ancestry of the Golden Horde. •[06:48] He describes how the results aid understanding of population genetics in central Eurasia. •[08:10] He lists the caveats and limitations of the study. •[09:53] Conclusion. About Our Guest: Ayken Askapuli PhD candidate University of Wisconsin-Madison View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2531003123 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Finding Genius Podcast
Can AI Unearth New Antibiotics From Ancient DNA? | A Conversation With Prof. César De La Fuente

Finding Genius Podcast

Play Episode Listen Later Apr 18, 2026 23:11


What can the DNA of Neanderthals, woolly mammoths, and ancient proteins tell us about the future of medicine? In this episode, Professor César de la Fuente sits down to discuss his fascinating research goal: using the power of machines to accelerate discoveries in biology and medicine… This conversation explores: The growing global health threat of antimicrobial resistance (AMR). Why ancient DNA and extinct organisms may hold clues for next-generation antibiotics. The role that AI plays in uncovering the genetic data of extinct organisms. What the future of machine biology could mean for human health. Prof. de la Fuente is Presidential Associate Professor at the University of Pennsylvania, where he leads the Machine Biology Group. He is one of the youngest tenured professors in the history of Penn Medicine. He completed postdoctoral research at MIT and earned his PhD from the University of British Columbia. He is widely recognized for pioneering the first computer-designed antibiotic shown to be effective in animal models, which is an achievement that helped launch the emerging field of AI-driven antibiotic discovery. His lab has since identified more than one million potential antimicrobial compounds through computational biology. In addition, Prof. de la Fuente has delivered over 350 invited lectures worldwide, co-authored an influential book on machine learning for drug discovery, secured multiple patents, and published more than 180 peer-reviewed papers in leading journals, including Cell, Science, Nature Communications, PNAS, and Advanced Materials. You can follow Prof. de la Fuente's latest discoveries and research here!

Choses à Savoir SANTE
Pourquoi certaines personnes de votre entourage vous font-elles vieillir plus vite ?

Choses à Savoir SANTE

Play Episode Listen Later Apr 16, 2026 1:54


On le sait intuitivement : certaines relations nous épuisent. Mais ce que la science révèle aujourd'hui va beaucoup plus loin. Certaines personnes de notre entourage pourraient littéralement accélérer notre vieillissement biologique.Une étude publiée le 22 janvier 2026 dans la prestigieuse revue PNAS, menée par des sociologues et spécialistes du vieillissement issus de plusieurs universités américaines, apporte des résultats frappants. Les chercheurs se sont intéressés à ce qu'ils appellent les “hasslers” : des individus qui génèrent du stress, des conflits ou rendent la vie plus difficile au quotidien.Leur conclusion est claire : ces relations négatives ne sont pas seulement désagréables, elles agissent comme de véritables accélérateurs du vieillissement.Pour le démontrer, les chercheurs ont analysé plus de 2 000 adultes, en combinant questionnaires sociaux et analyses biologiques à partir d'échantillons de salive. Grâce à des outils très avancés, ils ont mesuré l'âge biologique des participants, c'est-à-dire l'état réel de leurs cellules, indépendamment de leur âge chronologique.Et les résultats sont impressionnants.Chaque personne “toxique” supplémentaire dans l'entourage est associée à une augmentation d'environ 1,5 % du rythme de vieillissement. Concrètement, cela correspond à environ neuf mois de vieillissement biologique en plus.Pourquoi un tel effet ?Parce que ces relations agissent comme des sources de stress chronique. Or, le stress prolongé entraîne une cascade de réactions dans l'organisme : augmentation du cortisol, inflammation persistante, affaiblissement du système immunitaire. À long terme, ces mécanismes accélèrent l'usure du corps.Autrement dit, ces interactions négatives “passent sous la peau”. Elles modifient réellement notre fonctionnement biologique.L'étude montre aussi que ces relations ne sont pas rares. Près de 30 % des individus déclarent avoir au moins une personne de ce type dans leur entourage.Fait intéressant, toutes les relations négatives n'ont pas le même impact. Les tensions avec la famille ou certaines connaissances semblent plus délétères que celles avec un conjoint, probablement parce qu'elles sont plus difficiles à réguler ou à éviter.Ce que cette recherche met en lumière, c'est une idée essentielle : notre santé ne dépend pas uniquement de ce que nous mangeons ou de notre activité physique. Elle dépend aussi, profondément, de la qualité de nos relations.Au fond, bien s'entourer n'est pas seulement une question de bien-être émotionnel. C'est aussi, très concrètement, une question de longévité. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Science Salon
What Turns Sand Into Cells? How Nonliving Matter Becomes Alive

Science Salon

Play Episode Listen Later Apr 8, 2026 87:13


How does something living emerge from something that isn't?  In this episode, Lee Cronin pushes the question back even further: before cells, before DNA, before biology as we usually think of it, what kind of process could make matter start organizing itself into something alive? He and Michael Shermer get into assembly theory, RNA, autocatalysis, and the deeper puzzle of whether causation and selection may already be at work long before the first organism appears. The conversation also branches into consciousness, free will, and the possibility that life may be widespread in the universe, even if it looks nothing like life on Earth. Lee Cronin is Regius Professor of Chemistry at the University of Glasgow, Scotland, where he leads one of the world's largest multidisciplinary chemistry research groups. He has raised more than $35 million in grant funding, with current research income of $15 million, and has authored more than 350 peer-reviewed papers, including recent work published in Nature, Science, and PNAS. He and his team are trying to make artificial life forms, find alien life, explore the digitization of chemistry, understand how information can be encoded into chemicals and construct chemical computers.

PNAS Science Sessions
Concrete and carbon uptake

PNAS Science Sessions

Play Episode Listen Later Apr 6, 2026 10:46


How much carbon dioxide concrete can absorb Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Hessam Azarijafari explains the extent to which concrete can absorb carbon dioxide over its lifecycle. In this episode, we cover: •[00:00] Introduction. •[00:56] Construction engineer Hessam Azarijafari introduces us to the recipe for concrete. •[01:41] He explains how concrete absorbs carbon dioxide throughout its lifespan, and why this absorption is important. •[02:52] Azarijafari talks about the background of the study. •[03:45] He describes the model built for the study and the data source. •[05:59] Azarijafari tells the study's results, including variation in absorption across sectors and between the US and Mexico. •[07:41] He compares this analysis with previous estimates of concrete carbon absorption. •[08:25] He explains the takeaways from this study for policymakers and the concrete industry. •[09:36] He lists the caveats and limitations of the study. •[10:19] Conclusion. About Our Guest: Hessam Azarijafari Research Scientist Massachusetts Institute of Technology View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2515116122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
Hocken, Hängen, Hirn schützen – 2 Challenges, die Dein Training verändern (#566)

Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation

Play Episode Listen Later Apr 6, 2026 25:36


Bewegungskomplexität – noch nie gehört? Dann wird es Zeit. Denn wie komplex Du Dich bewegst, entscheidet darüber, wie gut Dein Gehirn altert. Und die meisten Trainingspläne ignorieren das komplett.Am Ende dieser Folge weißt Du, warum vielfältige, kognitiv fordernde Bewegung Dein Gehirn besser schützt als jedes Standardprogramm – und was eine Langzeitstudie mit über 8.600 Menschen über den Zusammenhang von Sportwahl und Lebenserwartung herausgefunden hat.Außerdem: Warum chronische Anspannung Dich blind für die Warnsignale Deines Körpers macht. Bock auf eine kleine Challenge? Dann erfährst Du, wie Du Deinen Körper in wenigen Minuten am Tag sofort fühlbar resilienter bekommst – in 30 Tagen oder weniger.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Vertiefende InhalteFolge 551: Das Weber-Fechner-GesetzSquat Challenge – 10 Min. Hocken/Tag × 30 TageTiefe Hocke, "Stoppuhr" läuft nur im HockenÜber den Tag verteilen (z.B. 10×1 Min.)Anfangs festhalten erlaubt, Fersen dürfen abhebenEinstieg: 2–3 Min./Tag, langsam steigernZiehen okay – Schmerz nichtHanging Challenge – 7 Min. Hängen/Tag × 30 TageAn Stange hängen, über den Tag verteilenWer nicht frei hängen kann: Füße am Boden lassenProgression: Mit Fußstütze → Frei passiv → Aktiv → EinarmigNicht direkt nach dem AufstehenBei Schulterproblemen vorsichtig startenLiteratur:Schnohr P et al. (2018). Various Leisure-Time Physical Activities Associated With Widely Divergent Life Expectancies: The Copenhagen City Heart Study. Mayo Clin Proc 93(12):1775-85.Rehfeld K et al. (2017). Dancing or Fitness Sport? The Effects of Two Training Programs on Hippocampal Plasticity and Balance Abilities in Healthy Seniors. Front Hum Neurosci 11:305.Rehfeld K et al. (2018). Dance training is superior to repetitive physical exercise in inducing brain plasticity in the elderly. PLoS ONE 13(7):e0196636. ← NEUVerghese J et al. (2003). Leisure activities and the risk of dementia in the elderly. N Engl J Med 348:2508-16.Proske U, Gandevia SC (2012). The proprioceptive senses. Physiol Rev 92(4):1651-97.Schiftan GS et al. (2015). The effectiveness of proprioceptive training in preventing ankle sprains. J Sci Med Sport 18(3):238-44.Raichlen DA et al. (2020). Sitting, squatting, and the evolutionary biology of human inactivity. PNAS 117(13):7115-21.Rojas-Jaramillo A et al. (2024). Impact of the deep squat on articular knee joint structures. Front Sports Act Living.Hartmann H et al. (2013). Analysis of the load on the knee joint and vertebral column with changes in squatting depth. Sports Med 43(10):993-1008.Sikirov D (2003). Comparison of straining during defecation in three positions. Dig Dis Sci 48(7):1201-5.Leong DP et al. (2015). Prognostic value of grip strength: findings from the PURE study. Lancet 386(9990):266-73.García-Hermoso A et al. (2018). Muscular Strength as a Predictor of All-Cause Mortality. Arch Phys Med Rehabil 99(10):2100-13.____________Shownotes und Übersicht aller Folgen.Trag Dich in Marks Dranbleiber Newsletter ein.Entdecke Marks Bücher.Folge Mark auf Instagram, Facebook, Strava, LinkedIn. Hosted on Acast. See acast.com/privacy for more information.

Authentic Biochemistry
On Metabolic RegulationImmune Network57.Authentic Biochemistry 24March2026 DR Daniel J Guerra

Authentic Biochemistry

Play Episode Listen Later Mar 25, 2026 49:18


ReferencesFront Immunol. 2021; 12: 613591Nature Communications2023. volume 14,Article number: 1611 PNAS 2001. vol.98.(5) February 27:2425- 2430Nature Communications 2018.Vol 9, Article number: 3630 McCoy/Minnie and Paige/Plant. 1929/1970 When the Levee Breaks.https://music.youtube.com/watch?v=uwiTs60VoTM&si=5Z5pmI9Has7EHrGpMozart, WA. 1791. Requiem in D Minor K.626https://music.youtube.com/playlist?list=OLAK5uy_nSNY0VtEjG1DYcoE6gg9tibETknwAWeLY&si=senu_gC7gLPsinMa

PNAS Science Sessions
Reconstructing extinct species' sense of smell

PNAS Science Sessions

Play Episode Listen Later Mar 23, 2026 10:43


Determining how well extinct animals could smell Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Quentin Martinez describes a reconstruction of olfactory capabilities in extinct mammals. In this episode, we cover: •[00:00] Introduction •[01:14] Evolutionary biologist Quentin Martinez tell why we want to reconstruct olfaction in extinct animals. •[02:35] He introduces the olfactory bulb endocast, or space within the skull that contained the olfactory bulb, and explains why it's important in evaluating olfaction in extinct animals. •[04:24] Martinez talks about studying the genomics of chemoreceptor genes, in addition to the bony structure of the olfactory bulb endocast. •[05:23] He tells about the results of the study. •[07:46] Martinez lists possible insights from reconstructing extinct animals' olfaction. •[08:53] He lists the caveats and limitations of the study. •[10:16] Conclusion. About Our Guest: Quentin Martinez Postdoctoral researcher Natural History Museum, Stuttgart, Germany View related content here: https://www.pnas.org/doi/10.1073/pnas.2510575122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Just the Zoo of Us
328: Apollo the African Grey Parrot w/ Dalton Mason!

Just the Zoo of Us

Play Episode Listen Later Mar 20, 2026 58:18


Join Ellen & Dalton Mason, creator and bird parent behind Apollo and Frens, for a look into life alongside the world-famous African grey parrot. You may have seen their videos on social media showing off Apollo's incredibly impressive vocabulary, answering questions and even speaking in full sentences, which have earned the bird a spot in the Guinness Book of World Records in 2025 - on top of all the pistachios, of course. We discuss animal cognition and what makes parrots such great models for animal intelligence, the brain soup machine, bird-proofing a home, parrots video calling each other, and so much more. Works Cited: "Birds have primate-like numbers of neurons in the forebrain" - Seweryn Olkowicz et al., PNAS, June 2016 "Birds of a Feather Video-Flock Together: Design and Evaluation of an Agency-Based Parrot-to-Parrot Video-Calling System for Interspecies Ethical Enrichment" - Rebecca Kleinberger et al., Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems, April 2023 African Grey Parrot flight calls: Peter Boesman, XC719450. Accessible at www.xeno-canto.org/719450 Links: Learn more about Apollo and Frens on their website: https://apolloandfrens.com/ Follow Apollo and Frens on YouTube, Instagram, and TikTok! For more information about us & our podcast, head over to our website! Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord! Follow Ellen on Instagram or BlueSky!  

Just the Zoo of Us
328: Apollo the African Grey Parrot w/ Dalton Mason!

Just the Zoo of Us

Play Episode Listen Later Mar 20, 2026 58:18


Join Ellen & Dalton Mason, creator and bird parent behind Apollo and Frens, for a look into life alongside the world-famous African grey parrot. You may have seen their videos on social media showing off Apollo's incredibly impressive vocabulary, answering questions and even speaking in full sentences, which have earned the bird a spot in the Guinness Book of World Records in 2025 - on top of all the pistachios, of course. We discuss animal cognition and what makes parrots such great models for animal intelligence, the brain soup machine, bird-proofing a home, parrots video calling each other, and so much more. Works Cited: "Birds have primate-like numbers of neurons in the forebrain" - Seweryn Olkowicz et al., PNAS, June 2016 "Birds of a Feather Video-Flock Together: Design and Evaluation of an Agency-Based Parrot-to-Parrot Video-Calling System for Interspecies Ethical Enrichment" - Rebecca Kleinberger et al., Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems, April 2023 African Grey Parrot flight calls: Peter Boesman, XC719450. Accessible at www.xeno-canto.org/719450 Links: Learn more about Apollo and Frens on their website: https://apolloandfrens.com/ Follow Apollo and Frens on YouTube, Instagram, and TikTok! For more information about us & our podcast, head over to our website! Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord! Follow Ellen on Instagram or BlueSky!  

Extinction Rebellion Podcast
News from a World in Flux Ep. 31: Biodiversity: suppressed report, finance gap, grassroot's protection, and Hannah Spencer

Extinction Rebellion Podcast

Play Episode Listen Later Mar 16, 2026 62:39


Extinction Rebellion's co-founder Clare Farrell and conservation scientist Dr Charlie Gardner team up once more to discuss issues and stories they feel are not getting enough airtime. They want to make sure that the latest news in science and important reports that are relevant to the climate and ecological crisis are flagged and explained in ways that are easy to understand.EPISODE 31: Biodiversity: suppressed report, finance gap, grassroot's protection, and Hannah SpencerIn this episode Clare and Charlie examine a censored UK intelligence assessment on biodiversity breakdown, the economic system driving ecosystem destruction, and the role of people power in protecting the planet. They also discuss what a surprising Green Party by-election victory might mean for climate politics.REFERENCESITV coverage of suppressed biodiversity national security reporthttps://www.youtube.com/watch?v=59DZiPdsOc8IPBES Business and Biodiversity Assessmenthttps://www.ipbes.net/bba-report/media-releaseRole of social movements in conserving nature New paper in PNAS based on Environmental Justice Atlashttps://www.pnas.org/doi/epdf/10.1073/pnas.2513327123NB the views in this show are Clare and Charlie's own and do not necessarily reflect the official position of Extinction Rebellion.---------------------Please, share, comment, subscribe, like, mobilise, and donate! https://chuffed.org/xr/ukExtinction Rebellion UK: https://extinctionrebellion.uk/

Food School: Smarter Stronger Leaner.
Why you know what to do and still don't do it — with UCLA Nudge Unit Co-Director Hengchen Dai.

Food School: Smarter Stronger Leaner.

Play Episode Listen Later Mar 15, 2026 67:45 Transcription Available


What does it truly take to change what we do — for yourself and at scale, sustainably in the real world?In this episode, Angela sits down with Hengchen Dai, Associate Professor at UCLA Anderson and co-director of the UCLA Nudge Unit, to explore the science behind why people do what they do, and what it takes to shift it.Hengchen brings rigorous academic research published in Nature and other notable publications, and field experiments run inside hospitals, university health systems, and national pharmacy chains with millions of participants. What emerges is a practical toolkit for anyone trying to create lasting change — whether you're a leader, a clinician, a policymaker, or just someone trying to get better at your own habits.Key Takeaways  -  Behaviour change is not one-size-fits-all — someone who skipped their flu shot this year (but got it last year) has a completely different barrier (forgetting, procrastination) than someone who has never been vaccinated (belief, scepticism). Targeting interventions based on past behaviour dramatically improves results. 

The Studies Show
Episode 97: The 2D:4D digit ratio

The Studies Show

Play Episode Listen Later Mar 10, 2026 63:23


The last few episodes have been pretty heavy. So here's… well, here's the 2D:4D ratio. Does the difference in length between your index finger and your ring finger reveal a huge amount about your personality (and much more besides)?Perhaps you won't be surprised by the answer. But we promise you'll be surprised by just how much effort scientists have put into finding out…The Science Fictions podcast is brought to you by Works in Progress magazine. And now, articles from Works in Progress magazine are read aloud to you by… Stuart from Science Fictions. Every week, a new audio version of a WiP article will be released for your listening enjoyment. Find out more at www.worksinprogress.news.Show notes* Anthropological paper from 1888 on hands* A “preliminary investigation” of digit ratio and personality (2002)* Meta-analysis on the topic of aggression from 2017* PNAS study on the digit ratios of London City traders* Vastly bigger, null study on 2D:4D and economic preferences* Study of digit ratio in orchestral musicians* Follow-up study with contradictory results on musical abilities* 2D:4D and the wearing of wedding rings* Original paper on sexuality and digit ratio* 2025 meta-analysis* Digit ratio and penis size* Manning's 2020 paper on COVID-19 and digit ratio* Critical follow-up letter* 2010 meta-analysis on athletic ability* Using 2D:4D to understand prehistoric cave paintings* 2021 BMJ Christmas Issue study on digit ratio and luck* Comparing inter- and intra-observer reliability for digit ratios across different measures (and Manning's concerns about similar)* Debate over “allometric scaling”: concerned; less concerned* 2024 meta-analysis on whether this even relates to other testosterone measures* 2026 meta-analysis still using 2D:4D (among other measures)CreditsThe Science Fictions podcast is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit sciencefictionspod.substack.com/subscribe

Astronomy Daily - The Podcast
Are We Missing Alien Signals? Space Weather, Brain Changes and the Mars Life Question

Astronomy Daily - The Podcast

Play Episode Listen Later Mar 9, 2026 14:59 Transcription Available


In today's episode, Anna and Avery explore five of the week's most compelling space and astronomy stories: a new SETI Institute study suggesting stellar space weather could be scrambling alien radio signals before they even leave their home systems; groundbreaking research revealing that spaceflight physically shifts and deforms the human brain inside the skull; the impressive engineering story behind Roscosmos restoring Baikonur's launch pad in record time ahead of the Progress MS-33 mission; a surprising new finding from Nature that Earth's elliptical orbit plays a much bigger role in shaping El Niño and global weather patterns than previously thought; and the endlessly fascinating question of whether asteroid impacts could allow microbes to travel between planets — including the possibility that life on Earth may have originated on Mars.   Stories Covered •       Why SETI may be missing alien radio signals — space weather around distant stars could be smearing narrowband signals beyond the reach of current detectors (SETI Institute, March 2026) •       Spaceflight physically shifts and deforms the brain inside the skull — new MRI study of 26 astronauts published in PNAS reveals extent of microgravity's neurological impact (University of Florida, March 2026) •       Baikonur's Site 31/6 launch pad fully restored after November 2025 damage — over 150 workers complete repairs in under two months, clearing path for Progress MS-33 on March 22 (NASASpaceFlight, March 2026) •       Earth's distance from the Sun found to dramatically alter seasons — new Nature study shows orbital eccentricity drives its own annual cycle in the Pacific cold tongue, influencing El Niño over millennia (UC Berkeley, March 2026) •       Did Earth life begin on Mars? New research examines how asteroid impacts could allow microbes to travel between planets via ejected rock (Universe Today, March 2026)   Connect With Us Website: astronomydaily.io Twitter/X, Instagram, TikTok, YouTube, Tumblr: @AstroDailyPod Part of the Bitesz.com Podcast NetworkBecome a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.

The Plant Free MD with Dr Anthony Chaffee: A Carnivore Podcast
Episode 340:Eating Raw Meat Every Day on Carnivore, Safe or Stupid?

The Plant Free MD with Dr Anthony Chaffee: A Carnivore Podcast

Play Episode Listen Later Mar 8, 2026 12:16


I raw meat the danger that some assume, or the superfood version of meat that others claim?  Let's look at the facts.   Some references: Micromorphology and geochemistry show controlled burning 30m inside Wonderwerk Cave, giving strong evidence that early Homo was using fire at least 1 million years ago. Berna F, Goldberg P, Horwitz LK, Brink JS, Holt S, Bamford M, Chazan M. 2012. Microstratigraphic evidence of in situ fire in the Acheulean strata of Wonderwerk Cave, Northern Cape province, South Africa. PNAS 109(20):E1215–E1220. PMID: 22474385. https://pubmed.ncbi.nlm.nih.gov/22474385/ Enamel crystal structure of carp teeth indicates low‑temperature, repeated heating, consistent with deliberate "oven‑like" cooking of fish by hominins ~780,000 years ago Zohar I, Biton R, Goren‑Inbar N, et al. 2022. Evidence for the cooking of fish 780,000 years ago at Gesher Benot Ya'aqov, Israel. Nature Ecology & Evolution 6:1797–1806. PMID: 36357607. https://www.nature.com/articles/s41559-022-01910-z   Join my NEW 90-day Carnivore Challenge group on Mighty Networks below! https://dr-chaffee-s-90-day-carnivore-challenge.mn.co/landing/ If you liked this and want to learn more go to my new website www.DrAnthonyChaffee.com

WICC 600
Melissa in the Morning: Exercise Impact Study

WICC 600

Play Episode Listen Later Mar 6, 2026 11:40


New research from Yale School of Medicine revealed how exercise can slow the growth of tumors. We spoke with Dr. Rachel Perry, the author of this study, shared key takeaways and easy ways to incorporate more movement in your day.For more information: Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition | PNAS

The Art of Charm
The People Around You Are Aging You | Social Intelligence Briefing

The Art of Charm

Play Episode Listen Later Feb 26, 2026 18:30


A new PNAS study found that the people who chronically stress you out don't just ruin your mood — they accelerate your biological aging. AJ and Johnny break down the research showing that each “Hassler” in your close network is linked to faster cellular aging, measurable at the DNA level. The real threat to your health isn't isolation — it's tolerating the wrong people. If you've optimized your fitness, discipline, and productivity but ignored your social environment, this episode explains why that might be costing you years. Chapters 00:00 – The DNA study on social stress02:00 – What a “Hassler” actually costs you04:00 – Why loneliness isn't the real problem06:30 – Family stress hits the hardest09:00 – Depth vs. breadth in relationships11:30 – Three practical moves to clean up your network Stop being over looked and unlock your X-Factor today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠unlockyourxfactor.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Check out Johnny on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@Social_Intell⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tiktok @social_intel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  The very qualities that make you exceptional in your field are working against you socially.  Visit the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠artofcharm.com/intel ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠for a social intelligence assessment and discover exactly what's holding you back. Download Stuff for free today by going to trystuff.app or by searching for “Stuff” in the App Store. You can get 50% off your first year of Extra Stuff by using code CHARM at checkout. Don't let financial opportunity slip through the cracks. Use code CHARM at monarch.com in your browser for HALF OFF your first year. Indulge in affordable luxury with Quince. Upgrade your wardrobe today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠quince.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for free shipping and hassle-free returns. Ready to turn your business idea into reality? Sign up for your $1/month trial at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠shopify.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Need to hire top talent—fast? Claim your $75 Sponsored Job Credit now at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Indeed.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. This year, skip breaking a sweat AND breaking the bank. Get your summer savings and shop premium wireless plans at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠mintmobile.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Save more than fifty percent on term life insurance at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SELECTQUOTE.COM/CHARM⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TODAY to get started  Curious about your influence level?  Get your Influence Index Score today! Take this 60-second quiz to find out how your influence stacks up against top performers at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠theartofcharm.com/influence⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check in with AJ and Johnny! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AJ on LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Johnny on LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AJ on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Johnny on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on TikTok⁠/ social stress, biological aging, epigenetic clock, toxic relationships, social health, stress and health, difficult family dynamics, social network audit, relationship boundaries, emotional stress, DNA aging, multiplex relationships, social environment, personal development Learn more about your ad choices. Visit megaphone.fm/adchoices

PNAS Science Sessions
The hidden costs of AI

PNAS Science Sessions

Play Episode Listen Later Feb 23, 2026 9:53


Hidden sustainability costs of AI Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers describe the sustainability impact of AI data centers. In this episode, we cover: •[00:00] Introduction •[01:20] Bronis de Supinski describes how the energy demands of AI data centers have increased in recent years and why improvements in data center energy efficiency will not necessarily reduce total energy expenditures •[03:08] Eric Masanet explains the difficulty of tracking and projecting the energy usage of AI data centers. •[05:12] Shaolei Ren describes the water usage and air pollution associated with AI data centers. •[07:30] Tevfik Kosar explains how AI might be leveraged as a tool to help address climate change and sustainability challenges. •[09:00] Final thoughts and conclusion. About Our Guests: Bronis de Supinski  Chief Technology Officer Lawrence Livermore National Laboratory  Eric Masanet  Professor University of California Santa Barbara Lawrence Berkeley National Laboratory Shaolei Ren  Associate Professor  University of California Riverside Tevfik Kosar  Professor University at Buffalo Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

The Art of Charm
Why You “Click” With Some People (It's Mostly Timing) | Social Intelligence Briefing

The Art of Charm

Play Episode Listen Later Feb 13, 2026 6:51


Why do some conversations feel effortless — while others fall flat even when you said nothing wrong? AJ and Johnny break down the neuroscience of “clicking,” including a 2022 PNAS study showing that connection often comes down to milliseconds. The secret isn't better stories or smarter answers — it's timing. Shorter response gaps signal attunement, alignment, and shared rhythm. Longer gaps quietly erode chemistry. If you've ever felt “off” despite saying the right things, this episode explains why — and how timing becomes social body language. 00:00 – The gap you can feel01:00 – Why chemistry isn't personality02:00 – The PNAS timing study03:15 – Same words, different timing04:15 – Why rhythm equals connection Stop being over looked and unlock your X-Factor today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠unlockyourxfactor.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Check out Johnny on ⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠@Social_Intell⁠⁠⁠⁠⁠⁠⁠⁠⁠ or on ⁠⁠⁠⁠⁠⁠⁠⁠⁠Tiktok @social_intel⁠⁠⁠⁠⁠⁠⁠⁠⁠  The very qualities that make you exceptional in your field are working against you socially.  Visit the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠artofcharm.com/intel ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠for a social intelligence assessment and discover exactly what's holding you back. Download Stuff for free today by going to trystuff.app or by searching for “Stuff” in the App Store. You can get 50% off your first year of Extra Stuff by using code CHARM at checkout. Don't let financial opportunity slip through the cracks. Use code CHARM at monarch.com in your browser for HALF OFF your first year. Indulge in affordable luxury with Quince. Upgrade your wardrobe today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠quince.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for free shipping and hassle-free returns. Ready to turn your business idea into reality? Sign up for your $1/month trial at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠shopify.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Need to hire top talent—fast? Claim your $75 Sponsored Job Credit now at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Indeed.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. This year, skip breaking a sweat AND breaking the bank. Get your summer savings and shop premium wireless plans at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠mintmobile.com/charm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Save more than fifty percent on term life insurance at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SELECTQUOTE.COM/CHARM⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TODAY to get started  Curious about your influence level?  Get your Influence Index Score today! Take this 60-second quiz to find out how your influence stacks up against top performers at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠theartofcharm.com/influence⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check in with AJ and Johnny! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AJ on LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Johnny on LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠AJ on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Johnny on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Art of Charm on TikTok⁠/ conversation timing, social connection, chemistry, attunement, communication skills, response time, neuroscience of connection, social rhythm, conversational flow, charisma, social intelligence, listening skills, human connection, conversational dynamics Learn more about your ad choices. Visit megaphone.fm/adchoices

PNAS Science Sessions
How mosquitoes time their bites

PNAS Science Sessions

Play Episode Listen Later Feb 9, 2026 9:53


Molecular regulation of mosquito biting timing Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Laura Duvall introduces a potential pathway for disrupting the biting behavior of mosquitoes. In this episode, we cover: •[00:00] Introduction •[00:57] Mosquito neuroscientist Laura Duvall introduces us to the normal biting behavior of mosquitoes. •[02:46] She tells why the biting behavior of the Aedes aegypti mosquito is of particular interest. •[03:24] Duvall describes findings regarding how mosquitoes' responses to CO2 vary over times of day. •[05:37] She introduces the PDF peptide that might be regulating timing of biting behavior and explains how losing that peptide changed mosquitoes' behavior. •[08:07] Duvall talks about the takeaways from the study for control of mosquito-borne illnesses. •[08:53] She lists the caveats and limitations of the study. •[09:26] Conclusion. About Our Guest: Laura Duvall Assistant Professor Columbia University View related content here: https://www.pnas.org/doi/10.1073/pnas.2520826122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast  Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter

Attitudes!
Sexism Rotting the Brain, U.S. Deporting Iranian Asylum Seekers, Alex Pretti and Microneedling

Attitudes!

Play Episode Listen Later Jan 29, 2026 66:25


We try and keep things light amidst the rising tide against ICE and the Trump administration (and as Bryan recovers from a procedure). Erin covers a study by PNAS showing how sexism physically changes and deteriorates the brain. Bryan discusses a current case of two gay Iranian asylum seekers on the verge of being deported back to where they fled persecution. GoFundMe Links: Support the Family of Parady La who died in ICE Custody Support the Family of Luis Beltrán Cruz who died in ICE custody Help Famiies Affected By ICE in Minneapolis Haven Watch MN If you have other resources you'd like us to highlight please send us a DM!See omnystudio.com/listener for privacy information.

Just the Zoo of Us
321: Norway Lemmings

Just the Zoo of Us

Play Episode Listen Later Jan 29, 2026 63:51


Ellen sets the record straight on Norway lemmings, busting over 400 years of myths. We discuss rodent audacity, ecological impacts that can be seen from space, spontaneous generation, Ole Worm, Atlantis, a Disney lie, and so much more.Works Cited:“Genome analyses suggest recent speciation and postglacial isolation in the Norwegian lemming” - Edana Lord et al., PNAS, June 2025“Aposematism and crypsis in a rodent: antipredator defence of the Norwegian lemming” - Malte Andersson, Behavioral Ecology and Sociobiology, April 2015"Vole and lemming activity observed from space" - Johan Olofsson et al, Nature Climate Change, May 2012"Ole Worm (1588-1654) - anatomist and antiquarian" - Rafael Romero Reveron & Luis A Arráez-Aybar, European Journal of Anatomy, July 2015"The Norwegian Lemming and its Migrations" - W. Duppa Crotch, Popular Science Monthly, August 1877"Lemming Suicide Myth: Disney Film Faked Bogus Behavior" - Riley Woodford, Alaska Department of Fish & Game, September 2003"Falling lemming populations" - Chris Smith, ScienceNorway.no, July 2012"Lemmings' loss is bounty for moss" - Bjørnar Kjensli, ScienceNorway.no, March 2012Links:For more information about us & our podcast, head over to our website!Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord!Follow Ellen on Instagram or BlueSky!

Tick Boot Camp
Episode 549: How Chronic Illness Really Works: Dr. Eric Gordon on Lyme, Mold, MCAS, and the Path Back to Health — Tick Boot Camp

Tick Boot Camp

Play Episode Listen Later Jan 10, 2026 79:52


In this episode of the Tick Boot Camp Podcast, Dr. Eric D. Gordon — globally recognized expert in Lyme disease, ME/CFS, mold toxicity, MCAS, mitochondrial dysfunction, and complex chronic illness — explains why chronic illness is never caused by a single factor and why recovery requires a strategic “order of operations.” Recorded after meeting at Project Lab Coat during NYFW, this conversation dives into chronic inflammation, immune dysregulation, why some people stay sick for years, why certain treatments backfire, how metabolomics reveals dysfunction that standard tests miss, and the future of individualized chronic illness care. Guest Bio Medical Director, Gordon Medical Associates, and President, Gordon Medical Research Center Dr. Gordon has 45+ years of experience treating the most complex chronic illness cases. He specializes in: Lyme disease and tick-borne infections ME/CFS and post-infectious illness Mold and mycotoxin exposure Mast Cell Activation Syndrome (MCAS) Autoimmune disease Environmental illness Mitochondrial dysfunction and metabolic collapse He co-authored the landmark 2016 PNAS metabolomics study with Dr. Robert Naviaux, which reshaped global understanding of ME/CFS and chronic inflammatory diseases. Key Topics Covered How Dr. Gordon became one of the world's leading chronic illness clinicians Why patient belief and validation are foundational to healing Why chronic illness cases don't fit conventional medical models Why herbs often worsen symptoms in MCAS or inflamed patients When pharmaceuticals help stabilize sensitive patients How chronic inflammation blocks trace mineral absorption The link between minerals, B vitamins, mitochondria, and NAD/NADH When detoxification helps — and when it causes more harm How childhood infections and environment shape lifelong immunity The massive impact of modern microbiome disruption Mold illness as the “great derailer” of Lyme treatment Why genetics like MTHFR and HLA are not destiny Why some people heal from Lyme without treatment How metabolomics and AI will usher in precision medicine What actually keeps people sick — accumulated compensations, not the tick bite What intuitive patients get right (and wrong) about their symptoms Timestamps 0:02 – Meeting Dr. Gordon at Project Labcoat 1:08 – Who he is and how he entered complex illness medicine 2:30 – Realizing conventional medicine fails chronic patients 5:45 – Why chronic illness doesn't fit standard algorithms 8:10 – Herbs vs antibiotics: what most people misunderstand 11:28 – Inflammation and why sensitive patients react to everything 13:45 – MCAS and immune overactivation 16:25 – Why herbal formulas can trigger flares 19:30 – Pharmaceuticals that calm inflammation 20:50 – Trace minerals, mitochondrial function, and NAD pathways 23:55 – Why standard labs can't see cellular dysfunction 26:10 – How childhood immune experiences shape resilience 28:40 – Environmental changes and microbiome decline 30:30 – Shoes, posture, fascia, lymphatics 36:35 – Structural healing and hypersensitive patients 41:20 – Founding Gordon Medical Associates 43:00 – Early discoveries with Lyme disease patients 48:30 – Detoxification, herbal protocols, and mold models 52:10 – Mold's ability to halt all progress 55:30 – Why mold affects some family members and not others 57:20 – How food supply antibiotics disrupt immunity 59:50 – Genetics are possibilities, not fate 1:03:20 – Why some people recover after a tick bite and others don't 1:07:00 – How AI and metabolomics will transform treatment 1:10:40 – Genes vs environment 1:13:30 – Chronic illness requires many small steps 1:16:00 – How to work with Dr. Gordon 1:18:30 – Final message of hope Pull Quotes “Chronic illness is not caused by one thing — and it's never healed by one thing.” “Herbs depend on your body's ability to modulate inflammation. If you can't dampen the fire, herbs feel like gasoline.” “Genetics are not destiny. They're possibilities.” “Mold makes every other treatment look like it's failing.” “You can absolutely get well — but there is no single magic bullet.” Call to Action If this episode brought you clarity or hope, please share it with someone navigating chronic Lyme, mold illness, MCAS, or ME/CFS. Subscribe and leave a review to help more people find this conversation and believe that healing is possible.