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A new PNAS study found that the people who chronically stress you out don't just ruin your mood — they accelerate your biological aging. AJ and Johnny break down the research showing that each “Hassler” in your close network is linked to faster cellular aging, measurable at the DNA level. The real threat to your health isn't isolation — it's tolerating the wrong people. If you've optimized your fitness, discipline, and productivity but ignored your social environment, this episode explains why that might be costing you years. Chapters 00:00 – The DNA study on social stress02:00 – What a “Hassler” actually costs you04:00 – Why loneliness isn't the real problem06:30 – Family stress hits the hardest09:00 – Depth vs. breadth in relationships11:30 – Three practical moves to clean up your network Stop being over looked and unlock your X-Factor today at unlockyourxfactor.com Check out Johnny on Instagram @Social_Intell or on Tiktok @social_intel The very qualities that make you exceptional in your field are working against you socially. Visit the artofcharm.com/intel for a social intelligence assessment and discover exactly what's holding you back. Download Stuff for free today by going to trystuff.app or by searching for “Stuff” in the App Store. You can get 50% off your first year of Extra Stuff by using code CHARM at checkout. Don't let financial opportunity slip through the cracks. Use code CHARM at monarch.com in your browser for HALF OFF your first year. Indulge in affordable luxury with Quince. Upgrade your wardrobe today at quince.com/charm for free shipping and hassle-free returns. Ready to turn your business idea into reality? Sign up for your $1/month trial at shopify.com/charm. Need to hire top talent—fast? Claim your $75 Sponsored Job Credit now at Indeed.com/charm. This year, skip breaking a sweat AND breaking the bank. Get your summer savings and shop premium wireless plans at mintmobile.com/charm Save more than fifty percent on term life insurance at SELECTQUOTE.COM/CHARM TODAY to get started Curious about your influence level? Get your Influence Index Score today! Take this 60-second quiz to find out how your influence stacks up against top performers at theartofcharm.com/influence. Check in with AJ and Johnny! AJ on LinkedIn Johnny on LinkedIn AJ on Instagram Johnny on Instagram The Art of Charm on Instagram The Art of Charm on YouTube The Art of Charm on TikTok/ social stress, biological aging, epigenetic clock, toxic relationships, social health, stress and health, difficult family dynamics, social network audit, relationship boundaries, emotional stress, DNA aging, multiplex relationships, social environment, personal development Learn more about your ad choices. Visit megaphone.fm/adchoices
Die Themen in den Wissensnachrichten +++ Warum Pferde-Wiehern akustisch ungewöhnlich ist +++ Muster auf Figuren aus der Altsteinzeit waren nicht nur Deko, sondern Zeichen +++ Wie viel Geld Frauen die Mutterschaft kostet +++**********Weiterführende Quellen zu dieser Folge:The high fundamental frequency in horse whinnies is generated by an aerodynamic whistle. Current Biology, 23.02.2026Humans 40,000 y ago developed a system of conventional signs. PNAS, 23.02.2026Can a motherhood premium in public transfer income offset the Danish motherhood earnings penalty? European Sociological Review, 18.11.2025The future of European outdoor summer sports through the lens of 50 years of the tour de France. Scientific Reports, 24.02.2026The power of victim narrative: Eponymous legislation increases voter sympathy and support. Psychology, Public Policy, and Law, advance online publicationAlle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Hidden sustainability costs of AI Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers describe the sustainability impact of AI data centers. In this episode, we cover: •[00:00] Introduction •[01:20] Bronis de Supinski describes how the energy demands of AI data centers have increased in recent years and why improvements in data center energy efficiency will not necessarily reduce total energy expenditures •[03:08] Eric Masanet explains the difficulty of tracking and projecting the energy usage of AI data centers. •[05:12] Shaolei Ren describes the water usage and air pollution associated with AI data centers. •[07:30] Tevfik Kosar explains how AI might be leveraged as a tool to help address climate change and sustainability challenges. •[09:00] Final thoughts and conclusion. About Our Guests: Bronis de Supinski Chief Technology Officer Lawrence Livermore National Laboratory Eric Masanet Professor University of California Santa Barbara Lawrence Berkeley National Laboratory Shaolei Ren Associate Professor University of California Riverside Tevfik Kosar Professor University at Buffalo Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
This episode is about women in math, from the perspective of sociology! Many thanks to Olga Paris-Romaskevich for the conversation. Olga's webpage: https://olga.pa-ro.net/The book "Matheuses": https://www.insmi.cnrs.fr/fr/matheusesHere is a link for Olga's talk on gender and mathematics: https://amubox.univ-amu.fr/s/SBRqbTLHSG5PFMFHere is a list of references Olga used when spoke about social psychology:1) Definition of social stereotype : (Leyens, Yzerbut, Schadron, 1994), slide 72) Stereotype threat result : Spencer, Steele, & Quinn (1999). Stereotype Threat and Women's Math Performance. Journal of Experimental Social Psychology, 35Social psychology : stereotype threat, slides 9 and 10 3) Aronson, J., Lustina, M. J., Good, C., Keough, K., Steele, C. M., & Brown, J. (1999). When White men can't do math: Necessary and sufficient factors in stereotype threat. Journal of Experimental Social Psychology, 35(1), 29–46.4) pp.12-13 : John VS Jennifer study Moss-Racusin, Dovidio, Brescoll, Graham, & Handelsman (2012). PNAS, 109, 16474-164795) Begeny, C. T., Ryan, M. K., Moss-Racusin, C. A., & Ravetz, G. (2020). In some professions, women have become well represented, yet gender bias persists- Perpetuated by those who think it is not happening. Science advances, 6(26), eaba7810:00 teaser1:03 Olya's book about "math girls"5:38 why there are so few women in math9:01 brilliance as social construct14:11 russian tease of women in math18:05 math in the sociology book22:35 why to make women only math events 30:33 and why we definitely need them34:19 how to make a good outreach event38:33 cool gender equity initiatives41:12 Mura's experience in math as a girl46:55 female role models in math51:18 homage to Sophia Kovalevskaya53:34 fun facts everyone should know!58:56 moral support for women in math
Why do some conversations feel effortless — while others fall flat even when you said nothing wrong? AJ and Johnny break down the neuroscience of “clicking,” including a 2022 PNAS study showing that connection often comes down to milliseconds. The secret isn't better stories or smarter answers — it's timing. Shorter response gaps signal attunement, alignment, and shared rhythm. Longer gaps quietly erode chemistry. If you've ever felt “off” despite saying the right things, this episode explains why — and how timing becomes social body language. 00:00 – The gap you can feel01:00 – Why chemistry isn't personality02:00 – The PNAS timing study03:15 – Same words, different timing04:15 – Why rhythm equals connection Stop being over looked and unlock your X-Factor today at unlockyourxfactor.com Check out Johnny on Instagram @Social_Intell or on Tiktok @social_intel The very qualities that make you exceptional in your field are working against you socially. Visit the artofcharm.com/intel for a social intelligence assessment and discover exactly what's holding you back. Download Stuff for free today by going to trystuff.app or by searching for “Stuff” in the App Store. You can get 50% off your first year of Extra Stuff by using code CHARM at checkout. Don't let financial opportunity slip through the cracks. Use code CHARM at monarch.com in your browser for HALF OFF your first year. Indulge in affordable luxury with Quince. Upgrade your wardrobe today at quince.com/charm for free shipping and hassle-free returns. Ready to turn your business idea into reality? Sign up for your $1/month trial at shopify.com/charm. Need to hire top talent—fast? Claim your $75 Sponsored Job Credit now at Indeed.com/charm. This year, skip breaking a sweat AND breaking the bank. Get your summer savings and shop premium wireless plans at mintmobile.com/charm Save more than fifty percent on term life insurance at SELECTQUOTE.COM/CHARM TODAY to get started Curious about your influence level? Get your Influence Index Score today! Take this 60-second quiz to find out how your influence stacks up against top performers at theartofcharm.com/influence. Check in with AJ and Johnny! AJ on LinkedIn Johnny on LinkedIn AJ on Instagram Johnny on Instagram The Art of Charm on Instagram The Art of Charm on YouTube The Art of Charm on TikTok/ conversation timing, social connection, chemistry, attunement, communication skills, response time, neuroscience of connection, social rhythm, conversational flow, charisma, social intelligence, listening skills, human connection, conversational dynamics Learn more about your ad choices. Visit megaphone.fm/adchoices
Et si nos différences de comportements sociaux tenaient à une poignée de neurones fonctionnant comme un simple interrupteur "ON/OFF" ? Une étude menée par des chercheurs israéliens sur des souris, publiée dans la revue PNAS, vient de mettre en lumière une découverte surprenante dans une région bien précise du cerveau : l'amygdale médiane.Une activité radicalement opposée selon le sexeL'amygdale est la zone du cerveau qui gère nos émotions et nos instincts sociaux. Les chercheurs y ont découvert un groupe de neurones dont l'activité est diamétralement opposée chez le mâle et la femelle :Chez les femelles : Ces neurones sont constamment actifs.Chez les mâles : Ils sont totalement inactifs la majeure partie du temps.C'est cette clarté de signal qui a stupéfié les scientifiques. On ne parle pas ici de nuances progressives, mais d'une différence binaire, presque "électrique", entre les deux sexes.Le sexe, mais aussi le statut socialCe qui est encore plus fascinant, c'est que ce circuit n'est pas figé. Chez le mâle, ces neurones ne sont pas "cassés" : ils peuvent s'allumer brusquement lors de changements majeurs dans sa vie sociale ou reproductive, notamment après un rapport sexuel.Plus étrange encore : cette activation ne semble pas dépendre directement des hormones sexuelles classiques (comme la testostérone), mais pourrait être liée à la prolactine, souvent appelée "hormone du lien". Cela suggère que l'expérience vécue et le contexte social peuvent littéralement "reparamétrer" le cerveau.Vers une plasticité du "cerveau paternel" ?Cette découverte fait écho à des recherches antérieures sur la parentalité. On sait que l'amygdale est très active chez les mères pour assurer la vigilance face au danger. Mais des études ont montré que chez les pères très impliqués dans le soin aux nouveau-nés (notamment dans les couples d'hommes ayant adopté), l'amygdale s'active tout autant que chez les mères.Conclusion pour votre podcast : Ce que nous enseigne cette étude, c'est que si nos cerveaux présentent des différences biologiques marquées à l'âge adulte, ils ne sont pas câblés de manière irréversible. Nos interactions sociales et nos expériences de vie possèdent le pouvoir de basculer des interrupteurs neuronaux, prouvant une fois de plus l'incroyable plasticité du cerveau face aux défis de la reproduction et de la survie sociale. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
In today's episode of Astronomy Daily, Anna and Avery cover five major stories from across the cosmos. SpaceX Crew-12 is targeting Thursday February 12th for launch to the International Space Station, after weather pushed back the Wednesday window. Meet the international crew of four and find out why this mission will run longer than usual. Our Sun has been active overnight, with sunspot region AR4366 firing off four M-class flares including an M2.8 that triggered a radio blackout over the Pacific. We look at what this means for space weather and aurora watchers. A stunning new study from Penn State, published in PNAS, has rewritten how scientists think amino acids formed in asteroid Bennu — and the implications for where life's ingredients can arise in the universe are profound. Italian scientists have confirmed the first lava tube on Venus, using 30-year-old radar data from NASA's Magellan mission. The structure is larger than any lava tube found on Earth, the Moon, or Mars. And finally — could coal be the key to finding advanced alien civilisations? A provocative new paper in the International Journal of Astrobiology makes the case. All stories sourced from NASA, Nature Communications, PNAS, and Phys.org. Links below. Source Links • Crew-12 weather delay: nasa.gov/blogs/spacestation • NSF launch preview: nasaspaceflight.com/2026/02/launch-preview-020926 • Bennu amino acids (PNAS): doi.org/10.1073/pnas.2517723123 • Venus lava tube (Nature Communications): doi.org/10.1038/s41467-026-68643-6 • Aliens and coal: phys.org/news/2026-02-advanced-aliens-exoplanets-large-coal.html • Solar activity: earthsky.org/sun/sun-news-activity-solar-flare-cme-aurora-updates Chapters / Timestamps (approximate) • 00:00 — Cold Open • 01:00 — Story 1: SpaceX Crew-12 Weather Delay • 05:00 — Story 2: Solar Flare Activity AR4366 • 07:30 — Story 3: Asteroid Bennu & Amino Acid Origins • 10:30 — Story 4: Venus Lava Tube Discovery • 13:30 — Story 5: Alien Civilisations & Coal Deposits • 17:00 — CloseBecome a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.
Molecular regulation of mosquito biting timing Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Laura Duvall introduces a potential pathway for disrupting the biting behavior of mosquitoes. In this episode, we cover: •[00:00] Introduction •[00:57] Mosquito neuroscientist Laura Duvall introduces us to the normal biting behavior of mosquitoes. •[02:46] She tells why the biting behavior of the Aedes aegypti mosquito is of particular interest. •[03:24] Duvall describes findings regarding how mosquitoes' responses to CO2 vary over times of day. •[05:37] She introduces the PDF peptide that might be regulating timing of biting behavior and explains how losing that peptide changed mosquitoes' behavior. •[08:07] Duvall talks about the takeaways from the study for control of mosquito-borne illnesses. •[08:53] She lists the caveats and limitations of the study. •[09:26] Conclusion. About Our Guest: Laura Duvall Assistant Professor Columbia University View related content here: https://www.pnas.org/doi/10.1073/pnas.2520826122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
We try and keep things light amidst the rising tide against ICE and the Trump administration (and as Bryan recovers from a procedure). Erin covers a study by PNAS showing how sexism physically changes and deteriorates the brain. Bryan discusses a current case of two gay Iranian asylum seekers on the verge of being deported back to where they fled persecution. GoFundMe Links: Support the Family of Parady La who died in ICE Custody Support the Family of Luis Beltrán Cruz who died in ICE custody Help Famiies Affected By ICE in Minneapolis Haven Watch MN If you have other resources you'd like us to highlight please send us a DM!See omnystudio.com/listener for privacy information.
Ellen sets the record straight on Norway lemmings, busting over 400 years of myths. We discuss rodent audacity, ecological impacts that can be seen from space, spontaneous generation, Ole Worm, Atlantis, a Disney lie, and so much more.Works Cited:“Genome analyses suggest recent speciation and postglacial isolation in the Norwegian lemming” - Edana Lord et al., PNAS, June 2025“Aposematism and crypsis in a rodent: antipredator defence of the Norwegian lemming” - Malte Andersson, Behavioral Ecology and Sociobiology, April 2015"Vole and lemming activity observed from space" - Johan Olofsson et al, Nature Climate Change, May 2012"Ole Worm (1588-1654) - anatomist and antiquarian" - Rafael Romero Reveron & Luis A Arráez-Aybar, European Journal of Anatomy, July 2015"The Norwegian Lemming and its Migrations" - W. Duppa Crotch, Popular Science Monthly, August 1877"Lemming Suicide Myth: Disney Film Faked Bogus Behavior" - Riley Woodford, Alaska Department of Fish & Game, September 2003"Falling lemming populations" - Chris Smith, ScienceNorway.no, July 2012"Lemmings' loss is bounty for moss" - Bjørnar Kjensli, ScienceNorway.no, March 2012Links:For more information about us & our podcast, head over to our website!Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord!Follow Ellen on Instagram or BlueSky!
Ellen sets the record straight on Norway lemmings, busting over 400 years of myths. We discuss rodent audacity, ecological impacts that can be seen from space, spontaneous generation, Ole Worm, Atlantis, a Disney lie, and so much more.Works Cited:“Genome analyses suggest recent speciation and postglacial isolation in the Norwegian lemming” - Edana Lord et al., PNAS, June 2025“Aposematism and crypsis in a rodent: antipredator defence of the Norwegian lemming” - Malte Andersson, Behavioral Ecology and Sociobiology, April 2015"Vole and lemming activity observed from space" - Johan Olofsson et al, Nature Climate Change, May 2012"Ole Worm (1588-1654) - anatomist and antiquarian" - Rafael Romero Reveron & Luis A Arráez-Aybar, European Journal of Anatomy, July 2015"The Norwegian Lemming and its Migrations" - W. Duppa Crotch, Popular Science Monthly, August 1877"Lemming Suicide Myth: Disney Film Faked Bogus Behavior" - Riley Woodford, Alaska Department of Fish & Game, September 2003"Falling lemming populations" - Chris Smith, ScienceNorway.no, July 2012"Lemmings' loss is bounty for moss" - Bjørnar Kjensli, ScienceNorway.no, March 2012Links:For more information about us & our podcast, head over to our website!Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord!Follow Ellen on Instagram or BlueSky!
Die Themen in den Wissensnachrichten: +++ Virus manipuliert Nachtfalterraupen +++ App kann Spuren von Dinosauriern erkennen +++ Fruchtbarkeitstests per Menstruationsbinde +++**********Weiterführende Quellen zu dieser Folge:Baculoviruses hijack host midgut-derived tachykinin to regulate phototactic climbing behavior and promote viral transmission, PNAS, 26.01.2026Identifying variation in dinosaur footprints and classifying problematic specimens via unbiased unsupervised machine learning, Pnas, 26.01.2026At Home Detection of Ovarian Health Biomarker in Menstruation Blood, medRxiv, 19.12.2025Dürremonitor Deutschland - Einschätzung des aktuellen Bodenfeuchtezustands, Helmholtz-Zentrum für Umweltforschung, (laufende Aktualisierung)Transmission through muscle tissue shapes polarization signals during cuttlefish courtship, PNAS, 26.01. 2026**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Die Themen in den Wissensnachrichten: +++ Wie Körperzellen auf Lichtsignale reagieren +++ Älteste Holzwerkzeuge der Welt gefunden +++ Influencer pushen unnötige Testosteron-Tests und -Behandlungen +++**********Weiterführende Quellen zu dieser Folge:Ideal efficacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissues, Nature Chemical Biology, 16.01.2026Evidence for the earliest hominin use of wooden handheld tools found at Marathousa 1 (Greece), Pnas, 26.01.2026Selling Masculinity – A Qualitative Analysis of Gender Representations in Social Media Content about “Low T”, Social Science & Medicine, 26.12.2025Large declines in organofluorine contamination indicated by subarctic marine mammal tissues, Pnas, 26.01.2026Reentry and disintegration dynamics of space debris tracked using seismic data, Science, 22.01.2026Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
How well flu vaccines protect public health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Lauren Meyers explains what the 2022-2023 influenza season taught us about the effectiveness of flu vaccines. In this episode, we cover: •[00:00] Introduction •[01:16] Computational epidemiologist Lauren Meyers introduces the health and hospitalization burden of seasonal influenza. •[01:47] She defines vaccine effectiveness. •[02:37] Meyers describes the features of the 2022-2023 flu season. •[04:05] She describes how the researchers estimated the hospitalizations prevented by vaccination. •[05:11] Meyers tells how vaccination of young adults protected adults over 65 years of age. •[06:56] She describes the takeaways of the study for future flu seasons. •[08:08] Meyers lists the caveats and limitations of the study. •[09:49] Conclusion. About Our Guest: Lauren Meyers Professor University of Texas at Austin View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2505175122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Episode Summary:Why do some people seem to attract good fortune? In this episode, I explore the neuroscience of serendipity – those chance discoveries and happy accidents that change everything. From Alexander Fleming's mouldy petri dish to the role of the brain's default mode network in connecting unrelated ideas, this episode uncovers the science behind what we call “luck.”You'll learn how curiosity, openness, and cognitive flexibility make us more likely to notice opportunity when it crosses our path – and how to train your brain to do just that.In this episode:How the term serendipity was born from a Persian fairy taleWhat neuroscience reveals about “accidental” discoveriesWhy “lucky” people simply notice more (Wiseman, 2003)How creative insights emerge from brain network interplay (Beaty et al., PNAS, 2018)Why our digital lives might be shrinking our chances for serendipity – and how to get it backThe Three Tools for Your Super Brain Kit to invite more insight, connection, and creative luck into your lifeThree Tools for Your Super Brain Kit:Expand your input – curiosity feeds connection.Practise attentive openness – notice what others miss.Reframe setbacks as openings – mistakes can be portals to discovery.Referenced research:Beaty, R. E. et al. (2018). PNAS, “Robust default–executive coupling supports creative cognition.”Wiseman, R. (2003). The Luck Factor.Busch, C. (2020). The Serendipity Mindset.Key Quote:“Serendipity isn't just luck – it's the brain's brilliance at connecting the unconnected.”Support this show http://supporter.acast.com/superbrain. Hosted on Acast. See acast.com/privacy for more information.
“Naturalistic stimuli open up new exploration…”Dr. Christopher Baldassano is an associate professor at Columbia University and leads the Dynamic Perception and Memory Lab. With a background in electrical engineering from Princeton and a PhD in computer science from Stanford, Chris has pioneered innovative approaches to understanding memory and cognition. Following a postdoc at Princeton with Uri Hasson and Ken Norman, he joined Columbia in 2018. His research focuses on how the brain processes, stores, and retrieves events using naturalistic stimuli, hidden Markov models, and multivariate analysis techniques.In this episode, Peter and Chris explore the fascinating world of event structures and memory. They discuss Chris's pioneering work on event scripts, neural frameworks that act as cognitive scaffolds for autobiographical memories. The conversation covers how the brain segments continuous experience into discrete events, the role of event boundaries in memory encoding, and the critical function of the hippocampus in organizing these temporal structures. Chris explains his use of naturalistic stimuli and hidden Markov models to reveal the subtle dynamics of how we combine recurring information to respond more efficiently to future experiences. Along the way, Chris shares valuable insights on the evolution of neuroscience research and offers thoughtful advice for aspiring scientists navigating the field.We hope you enjoy this episode!Chapters:00:00 - Introduction07:37 - Transitioning from Computer Science to Neuroscience13:01 - Exploring Naturalistic Stimuli in Neuroscience18:11 - Hidden Markov Models in Narrative Perception22:46 - Event Boundaries and Memory Encoding27:49 - The Role of the Hippocampus in Memory33:01 - Implications for Mental Health and Memory Disorders38:19 - Enhancing Memory Techniques41:11 - Contextualization in Memory46:19 - Understanding Brain States49:01 - AI and Contextual Knowledge53:29 - Infant Cognition and Event Structures01:01:31 - Future Directions in ResearchWorks mentioned:2:28 - https://www.youtube.com/watch?v=jPLWOBmaLkY(Baldassano talk at NIH workshop on naturalistic stimuli)14:42 - https://pubmed.ncbi.nlm.nih.gov/28772125/(Baldassano et al., 2017 - Neuron - "Discovering Event Structure in Continuous Narrative Perception and Memory")15:02 - https://pubmed.ncbi.nlm.nih.gov/30249790/(Baldassano et al., 2018 - Journal of Neuroscience - "Representation of Real-world Event Schemas During Narrative Perception")18:24 - https://pubmed.ncbi.nlm.nih.gov/29087305/(Vidaurre, Smith & Woolrich, 2017 - PNAS - "Brain network dynamics are hierarchically organized in time" - using Markov models in a different way)19:41 - https://pubmed.ncbi.nlm.nih.gov/17338600/(Zacks et al., 2007 - Psychological Bulletin - "Event perception: A mind-brain perspective" - foundational work on event boundary processes)27:04 - https://pubmed.ncbi.nlm.nih.gov/27121839/(Huth et al., 2016 - Nature - "Natural speech reveals the semantic maps that tile human cerebral cortex" - semantic information stored throughout the brain)37:15 - https://pubmed.ncbi.nlm.nih.gov/22982082/(LePort et al., 2012 - Neurobiology of Learning and Memory - Jim McGaugh's study on highly superior autobiographical memory)53:01 - https://pubmed.ncbi.nlm.nih.gov/36252007/(Yates et al., 2022 - PNAS - "Neural event segmentation of continuous experience in human infants")Episode producers:Xuqian Michelle Li
Die Themen in den Wissensnachrichten: +++ Etablierte Musiker*innen landen mehr Top-Songs - und die bleiben lange oben in den Charts +++ Auch in Zoos ist Überalterung ein Problem +++ Lichtverschmutzung sorgt für längere Pollensaison +++**********Weiterführende Quellen zu dieser Folge:Is it getting harder to make a hit? Evidence from 65 years of US music chart history, EPJ Data Science, 02.09.2025Energy demand and decarbonization in 2025 and beyond, Nature Reviews Clean Technology, 20.01.2026Timing structures in live comedy: A matched-sequence approach to mapping performance dynamics, PNAS Nexus, 20.01.2026Aging populations threaten conservation goals of zoos, PNAS, 20.01.2026Does School Social Work Work? The Impact of School Social Workers on Youth Crime and Education, Januar 2026Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Here's a cheery one for our first episode of the year. Guess what happens when you give several sets of scientists the same dataset and ask them to answer the same question? Well, they all find the same results, right? Right!?Sadly not. This “Many Analysts” problem has been analysed and debated in multiple different scientific fields and across several papers. We cover them in this episode. What does it tell us about the objectivity of science if different teams draw different conclusions from the exact same data?The Science Fictions podcast is brought to you by Works in Progress magazine. Their excellent new article on how we're living in “the golden age of vaccine development”, as discussed on the show, can be found (along with the rest of their articles on science, history, and technology), at worksinprogress.co. We're very grateful that they support the podcast.Show notes* 2015 Nature commentary article on “crowdsourced research” (on racism in football)* And the full 2018 writeup titled “Many Analysts, One Data Set”* Gelman and Loken on the “Garden of Forking Paths”* 2020 many-analysts neuroscience (fMRI) paper* And the plan for the similar study on EEG* 2022 PNAS many-analysts paper on the “hidden universe of uncertainty”* 2026 critique on ideological bias from George Borjas* 2023 critique on effect sizes vs. statistical significance* 2025 ecology & evolution many-analysts paper on blue tits and eucalyptus* 2025 economics many-analysts paper with results on data cleaning* 2024 PNAS critique of many-analysts research* Julia Rohrer's critique of multiverse analysisCreditsThe Science Fictions podcast is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit sciencefictionspod.substack.com/subscribe
Die Themen in den Wissensnachrichten: +++ Was uns online besonders stresst +++ Warum gibt es gleichgeschlechtlichen Sex +++ Badewasser in Pompeji ganz schön schmutzig +++**********Weiterführende Quellen zu dieser Folge:Examining the Association Between Internet Use and Perceived Stress, JMIR, 9.1.2026Ecological and social pressures drive same-sex sexual behaviour in non-human primates, Nature Ecology & Evolution, 12.01.2026Seeing Roman life through water: Exploring Pompeii's public baths via carbonate deposits, PNAS, 12.01.2026Motivation under aversive conditions is regulated by a striatopallidal pathway in primates, Current Biology, 9.1.2026Invasion of bacteria swimming upstream into microstructured devices, Newton, 5.01.2026Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Air quality and pet health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Sarah Shackleton shares climate lessons learned from 6 million-year-old ice. In this episode, we cover: •[00:00] Introduction •[01:02] Paleoclimate and ice scientist Sarah Shackleton introduces the information researchers can glean from ice cores. •[02:02] She recounts the age extent of previous ice cores. •[03:03] Shackleton describes the Allan Hills Ice Area. •[04:35] She describes the method for ascertaining the age of air in an ice core. •[05:49] She explains the results of the study and the insights into the climate in Antarctica over the last 6 million years. •[06:32] Shackleton talks about the ice at the base of the core, and the research implications of the study. •[08:13] Caveats and limitations of the study. •[09:11] Conclusion. About Our Guest: Sarah Shackleton Assistant scientist Woods Hole Oceanographic Institution View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2502681122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
In this episode of the Tick Boot Camp Podcast, Dr. Eric D. Gordon — globally recognized expert in Lyme disease, ME/CFS, mold toxicity, MCAS, mitochondrial dysfunction, and complex chronic illness — explains why chronic illness is never caused by a single factor and why recovery requires a strategic “order of operations.” Recorded after meeting at Project Lab Coat during NYFW, this conversation dives into chronic inflammation, immune dysregulation, why some people stay sick for years, why certain treatments backfire, how metabolomics reveals dysfunction that standard tests miss, and the future of individualized chronic illness care. Guest Bio Medical Director, Gordon Medical Associates, and President, Gordon Medical Research Center Dr. Gordon has 45+ years of experience treating the most complex chronic illness cases. He specializes in: Lyme disease and tick-borne infections ME/CFS and post-infectious illness Mold and mycotoxin exposure Mast Cell Activation Syndrome (MCAS) Autoimmune disease Environmental illness Mitochondrial dysfunction and metabolic collapse He co-authored the landmark 2016 PNAS metabolomics study with Dr. Robert Naviaux, which reshaped global understanding of ME/CFS and chronic inflammatory diseases. Key Topics Covered How Dr. Gordon became one of the world's leading chronic illness clinicians Why patient belief and validation are foundational to healing Why chronic illness cases don't fit conventional medical models Why herbs often worsen symptoms in MCAS or inflamed patients When pharmaceuticals help stabilize sensitive patients How chronic inflammation blocks trace mineral absorption The link between minerals, B vitamins, mitochondria, and NAD/NADH When detoxification helps — and when it causes more harm How childhood infections and environment shape lifelong immunity The massive impact of modern microbiome disruption Mold illness as the “great derailer” of Lyme treatment Why genetics like MTHFR and HLA are not destiny Why some people heal from Lyme without treatment How metabolomics and AI will usher in precision medicine What actually keeps people sick — accumulated compensations, not the tick bite What intuitive patients get right (and wrong) about their symptoms Timestamps 0:02 – Meeting Dr. Gordon at Project Labcoat 1:08 – Who he is and how he entered complex illness medicine 2:30 – Realizing conventional medicine fails chronic patients 5:45 – Why chronic illness doesn't fit standard algorithms 8:10 – Herbs vs antibiotics: what most people misunderstand 11:28 – Inflammation and why sensitive patients react to everything 13:45 – MCAS and immune overactivation 16:25 – Why herbal formulas can trigger flares 19:30 – Pharmaceuticals that calm inflammation 20:50 – Trace minerals, mitochondrial function, and NAD pathways 23:55 – Why standard labs can't see cellular dysfunction 26:10 – How childhood immune experiences shape resilience 28:40 – Environmental changes and microbiome decline 30:30 – Shoes, posture, fascia, lymphatics 36:35 – Structural healing and hypersensitive patients 41:20 – Founding Gordon Medical Associates 43:00 – Early discoveries with Lyme disease patients 48:30 – Detoxification, herbal protocols, and mold models 52:10 – Mold's ability to halt all progress 55:30 – Why mold affects some family members and not others 57:20 – How food supply antibiotics disrupt immunity 59:50 – Genetics are possibilities, not fate 1:03:20 – Why some people recover after a tick bite and others don't 1:07:00 – How AI and metabolomics will transform treatment 1:10:40 – Genes vs environment 1:13:30 – Chronic illness requires many small steps 1:16:00 – How to work with Dr. Gordon 1:18:30 – Final message of hope Pull Quotes “Chronic illness is not caused by one thing — and it's never healed by one thing.” “Herbs depend on your body's ability to modulate inflammation. If you can't dampen the fire, herbs feel like gasoline.” “Genetics are not destiny. They're possibilities.” “Mold makes every other treatment look like it's failing.” “You can absolutely get well — but there is no single magic bullet.” Call to Action If this episode brought you clarity or hope, please share it with someone navigating chronic Lyme, mold illness, MCAS, or ME/CFS. Subscribe and leave a review to help more people find this conversation and believe that healing is possible.
Uz precīzijas medicīnu tiek liktas lielas cerības nākotnē, īpaši onkoloģijā, kur šāda veida terapijas nozīmētu veiksmīgi izārstētu vēzi bez smagām blaknēm veselajām organisma šūnām. Kā dažādas medicīnas procedūras, terapijas metodes un medikamentus ietekmē mūsu katra gēni, vides un dzīvesveida apstākļi? Kādām slimībām jau šobrīd palīdz precīzijas medicīna un ko tā īsti nozīmē? Raidījumā Zināmais nezināmajā skaidro Inese Čakstiņa-Dzērve, bioloģijas doktore, Rīgas Stradiņa universitātes Mikrobioloģijas un virusoloģijas institūta vadošā pētniece, docente Rīgas Stradiņa universitātes Medicīnas fakultātē, un Egija Berga-Švītiņa, Bērnu klīniskās universitātes slimnīcas ģenētiķe. Raidījuma noslēgumā Zinātnes ziņas Kas vieno un atšķir optimistus un pesimistus? Optimistiski cilvēki savā starpā esot līdzīgi – tā pagājušajā gadā publicētā pētījumā žurnālā “PNAS” apgalvojuši zinātnieki no Japānas un Austrālijas. “Zināmais nezināmajā” viedokli par publikāciju vaicājam pašmāju pētniekam, un šoreiz tā ir psiholoģe, kā arī lektore un pētniece Rīgas Tehniskajā universitātē Anete Hofmane. Viņa norāda, ka pēdējo desmit gadu laikā ir ienākusi tendence runāt par pozitīvo psiholoģiju un līdz ar to – arī par optimismu. Saruna par optimismu kā cerību saglabāšanu attiecībā uz nākotni un kā psiholoģisku resursu.
China's science leadership Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, James Evans explains how and why China's leadership in global science is rising. In this episode, we cover: •[00:00] Introduction •[00:56] Social and complex systems scientist James Evans recounts the recent history of the trajectories of science in the U.S. and in China. •[01:50] He explains how to measure a country's scientific leadership and introduces the data sources used in the study. •[04:18] Evans tells the results of the study, and talks about some areas of science in which China's leadership has particularly advanced. •[06:20] He lists the key takeaways from the study for policymakers and the benefits of global science engagement. •[08:47] Evans talks about the caveats and limitations of the work. •[09:54] Conclusion About Our Guest: James Evans Max Plofsky Professor of Sociology and Data Science University of Chicago View related content here: https://www.pnas.org/doi/abs/10.1073/pnas.2414893122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
References Nature Neuroscience 2009.volume 12, pages 988–995 The Journal of Pharmacology and Experimental Therapeutics 2023. Volume 385, Supplement 3, June: 343 Alcohol Clin Exp Res. 2016 Sep 1;40(10):2030–2042. PNAS 2013. vol. 110 no. 45 November 5,Rom J Morphol Embryol .2021 Apr-Jun;62(2):553-561Alcohol, 2017-12-01, Volume 65, Pages 51-62Cells 2022, 11(11), 1773;Journal of Neuroscience 17 April 2024, 44 (16) e0918232024;Paige/Plant 1971. Stairway to Heavenhttps://open.spotify.com/track/5CQ30WqJwcep0pYcV4AMNc?si=2c35ff68c11e464fWinwood, S. 1968. Dear Mr. Fantasy Traffichttps://open.spotify.com/track/2pKGqD3UQBAdi0dCLNYR7a?si=dcfb9f099f9d40c0Seeger, P. 1965 Turn Turn Turn. Byrdshttps://open.spotify.com/track/5qBqBdfTEIWJwAS0Jm2F5R?si=ae25a0be1e474d96
Die Themen in den Wissensnachrichten: +++ So wurde in der Steinzeit Wein hergestellt +++ Vorsicht, welches Hobby auf den Lebenslauf kommt +++ Weltrekord: Neue Amöbenart überlebt bei 63 Grad +++**********Weiterführende Quellen zu dieser Folge:Spontaneous fermentation of raisin water to form wine, Scientific Reports, 25.11.25Game Over or Game Changer? The Impact of Applicants' Gaming Skills on Their Hirability, Journal of Personnel Psychology, 04.11.25A geothermal amoeba sets a new upper temperature limit for eukaryotes, bioRxiv, 24.11.25Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection, PNAS, 23.12.25Talking-associated cognitive loads degrade the quality of gaze behavior, PLOS One, 06.10.25Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Deze week hoor je in NRC Vandaag onze serie Wilde eeuwen, het begin. Een van de verhalende series die we dit jaar maakten: perfect voor tijdens de dagen rond Kerst.Het is 12.000 jaar geleden. Sjamaan Slata wandelt naar Göbleki Tepe, bakt brood en hallucineert op beschimmelde rogge. Zullen zijn visioenen de landbouw vooruit helpen?Heeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze redactie via podcast@nrc.nl.Voor deze aflevering is onder meer gebruikt gemaakt van deze literatuur:Oliver Dietrich ‘Shamanism at Early Neolithic Göbekli Tepe, southeastern Turkey. Methodological contributions to an archaeology of belief' in Praehistorische Zeitschrift, in mei 2024. Steven Mithen ‘Shamanism at the transition from foraging to farming in Southwest Asia: sacra, ritual, and performance at Neolithic WF16 (southern Jordan)' in The Journal of the Council for British Research in the Levant, in September 2022.David Graeber en David Wengrow. ‘The Dawn of Everything, A New History of Humanity', bij Penguin in 2022. Li Liu e.a. ‘Fermented beverage and food storage in 13,000 y-old stone mortars at Raqefet Cave, Israel: Investigating Natufian ritual feasting' in in oktober 2018. Amaia Arranz-Otaeguia e.a. ‘Archaeobotanical evidence reveals the origins of bread 14,400 years ago in northeastern Jordan' in PNAS, op 13 juli 2018.Leore Grosman e.a. ‘A Natufian Ritual Event' in Current Anthropology, in juni 2016.Marion Benz ‘Symbols of Power - Symbols of Crisis? A Psycho-Social Approach to Early Neolithic Symbol Systems', Neo-Lithics, in januari 2014. Leore Grosman e.a. ‘A 12,000-year-old Shaman burial from the southern Levant (Israel)' in PNAS, op 18 november 2008. Zohar Kerem e.a. ‘Chickpea domestication in the Neolithic Levant through the nutritional perspective' in Journal of Archaeological Science, in augustus 2007.Tekst en presentatie: Hendrik SpieringRedactie en regie: Mirjam van ZuidamMuziek, montage en mixage: Rufus van BaardwijkBeeld: Jeen BertingVormgeving: Yannick MortierZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.
Send us a textRene Kizilcec is an Associate Professor at Cornell University, where he directs the Cornell Future of Learning Lab and leads the National Tutoring Observatory. His research focuses on learning science, AI in education, and the behavioral and computational factors that shape student success. His work has appeared in Science, PNAS, and other top journals.
Roxy's Ride & Inspire RAWcast - Mountain Bike & Mindset Podcast
In today's episode, we dig into one of the most powerful (and most misunderstood) features of the human brain: your built in negativity bias. You'll learn:why your brain holds onto negative experienceswhy “reality” is filtered, not objectivehow the Reticular Activating System (RAS) decides what you noticeand how mountain biking is a surprisingly effective tool for retraining your attentionIf you've ever wondered why one bad ride, one mistake, or one negative comment sticks in your mind far longer than all the good stuff combined, this episode will finally help you make sense of it and CHANGE it! You'll learn practical, science-backed tools to start training your attention today (on the trail and in daily life) so your brain becomes better at noticing possibilities, capabilities, and micro-wins instead of dangers and mistakes to build a more supportive inner environment.We explore:Baumeister et al., “Bad Is Stronger Than Good”the fast subcortical threat pathway that triggers your amygdala before you can thinkwhy positive moments fade unless you consciously reinforce themhow attention literally rewires your neural pathway Hebbian learningand why your RAS acts like a “bouncer,” filtering your world based on what you engage with✨ Patreon Bonus: Patrons get a free downloadable cheat sheet that summarizes all tools and concepts from today's episode.Join here to get it PLUS other exclusive perks: https://www.patreon.com/c/rideandinspire This episode is not sponsored. It's made possible by the lovely humans who support my work on Patreon. If you want to help me keep creating science-based, real-talk MTB content, JOIN my Patreon, thank you.
Die Themen in den Wissensnachrichten: +++ Im alten Nubien wurden auch Kleinkinder schon tätowiert +++ Weniger Alkohol führt auch zu besseren Schulnoten +++ Seltene Adoption eines Eisbär-Jungen durch Eisbär-Mutter beobachtet +++ **********Weiterführende Quellen zu dieser Folge:Revealing tattoo traditions in ancient Nubia through multispectral imaging, PNAS, 15.12.2025Minimum legal drinking age and educational outcomes, Journal of Health Economics, 07.11.2025Electronic Nose for Indoor Mold Detection and Identification, Advanced Sensor Research, 10.11.2025Quantification of the radiative forcing of contrails embedded in cirrus clouds, Nature Communications, 28.11.2025Scoperte migliaia di orme di dinosauri nel Parco Nazionale dello Stelvio, Museo di Storia Naturale die Milano, 16.12.2025**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Next stop - the moon! Jeremy Hansen stops by our studio to chat about how he's prepping to be the first Canadian to go to the moon.Plus:Santa's reindeer may be losing their antlers –– and climate change could be the culpritReindeer are the only animal in the deer family where the females also grow antlers, and they typically have a full rack over the wintertime and drop them in June when they give birth. University of Guelph PhD student Allegra Love was monitoring reindeer on Fogo Island in Newfoundland, when she made a surprising discovery that female reindeer are losing and growing their antlers much earlier than usual. This can put more stress on the animal during a crucial part of their pregnancy, and the researchers think this could eventually lead to the reindeer losing their antlers altogether. The work was published in the journal Ecosphere.Pterosaur brains reveal clues about why these mighty fliers took to the skiesFlight has only evolved among vertebrates three times — in bats, birds, and first in pterosaurs. How pterosaurs first took to the skies was always a mystery to scientists, until the discovery of a fossilized 230-million year old pterosaur relative in Brazil. An international team, including Ohio University professor Lawrence Witmer, used an MRI for detailed analysis of the fossilized skull, to pinpoint the miniscule brain changes that happened as the animal developed the capacity to fly. The research was published in the journal Current Biology.Scientists are using AI to find life in 3 billion year old rocksEarth's earliest signs of life are often incredibly difficult to detect. An international team of researchers have developed a new tool that uses AI to find “whispers” of life locked inside ancient rocks. Using this tool, the researchers, including astrobiologist Michael Wong from Carnegie Science, were able to detect fresh chemical evidence of life in rocks that are 3.3 billion years old. This tool can not only be used to explore the origins of life here on Earth, but also on Mars and other planetary bodies. The work was published in the journal PNAS.
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, Vanessa sits down with Dr. Howard, the lead author of a brand-new PNAS study that is challenging one of the most widely accepted ideas in human metabolism. For years, many scientists believed that our bodies operate within a fixed daily calorie "budget," and that after a certain point, increasing activity doesn't increase total calorie burn. But Dr. Howard's new research suggests the story may be far more dynamic — and far more empowering — than we ever realized. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. This conversation explores what this new evidence could mean for: How we think about calorie burn Why activity matters (in ways we didn't fully understand before) The role of fueling, recovery, and energy balance What actually drives fat loss and body recomposition How to train smarter, not harder Mentioned in this episode: Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation — published in Proceedings of the National Academy of Sciences (PNAS). Read the full study here → PNAS DOI 10.1073/pnas.2519626122 NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 20% off on the Tone Device breath ketone analyzer or the Tone LUX Crystal Red Light Therapy Mask or the at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Genetic history of dog domestication Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore the impact of domestication on dog genetics and behavior. In this episode, we cover: •[00:00] Introduction •[01:00] Greger Larson explains how the history of gene flow between dogs and their wild relatives differs from what we know about other domestic species. •[02:38] Audrey Lin finds that low levels of wolf ancestry are found in almost two thirds of dog breeds. •[04:18] Linus Girdland Flink documents evidence of two genetic wolves on a remote Scandinavian island that may have been under human control. •[06:13] Clément Car explores how the mating systems of free-ranging village dogs could provide insight into canine domestication •[07:43] Katia Bougiouri explains how she used a statistical method to improve ancient genomes and what her results reveal about the history of inbreeding in dogs. •[09:21] Lachie Scarsbrook explains how he used museum specimens to reconstruct the history of inbreeding in German Shepherd Dogs. •[11:10] Eleanor Raffan analyzes genetic data and owner-submitted behavioral questionaries from 1,343 golden retrievers. •[12:54] Kathryn Lord finds that genetic testing cannot accurately predict canine behaviors. •[14:25] Final thoughts and conclusion. About Our Guest: Greger Larson Professor University of Oxford Audrey Lin Gerstner Postdoctoral Scholar American Museum of Natural History Linus Girdland Flink Lecturer University of Aberdeen Clément Car Postdoctoral Researcher University of Gdańsk Katia Bougiouri Postdoctoral Researcher University of Copenhagen Lachie Scarsbrook Postdoctoral Researcher University of Oxford, Ludwig Maximilian University of Munich Eleanor Raffan University Associate Professor University of Cambridge Kathryn Lord Postdoctoral fellow University of Massachusetts Chan Medical School View related content here: https://www.pnas.org/doi/10.1073/pnas.2528616122 https://www.pnas.org/doi/10.1073/pnas.2421768122 https://www.pnas.org/doi/10.1073/pnas.2421759122 https://www.pnas.org/doi/10.1073/pnas.2421756122 https://www.pnas.org/doi/10.1073/pnas.2416980122 https://www.pnas.org/doi/10.1073/pnas.2421755122 https://www.pnas.org/doi/10.1073/pnas.2421757122 https://www.pnas.org/doi/10.1073/pnas.2421752122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Die Themen in den Wissensnachrichten: +++ Unser Gehirn ist erst mit Anfang 30 auf dem Entwicklungs-Höhepunkt +++ Bettwanzen als Beweismittel +++ Warum wir im Bett bleiben wollen, wenn wir krank sind +++**********Weiterführende Quellen zu dieser Folge:Topological turning points across the human lifespan, Nature Communications, 25.11.2025Protocol for tropical bed bug use as forensic tools, Forensic Science International, Oktober 2024Sequence organization of mother–infant interactions in chimpanzees (Pan troglodytes schweinfurthii) in the wild, Proceedings of the Royal Society B, 26.11.2025IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness, Cell, 25.11.2025Mating system of free-ranging domestic dogs and its consequences for dog evolution, PNAS, 24.11.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Air quality and pet health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Stephen Jarvis explores the health impacts of poor air quality on pets. In this episode, we cover: •[00:00] Introduction •[00:51] Environmental economist Stephen Jarvis explains how he became interested in the effects of air quality on pets. •[01:59] He talks about the similarities in exposure between humans and pets, and introduces the veterinary dataset used in the study. •[03:30] Jarvis explains the results of the study and the potential physiological effects of poor air quality. •[05:40] He talks about the implications of reducing air pollution for petcare and the takeaway messages of the study. •[08:17] Jarvis explains the caveats and limitations of the study. •[09:14] Conclusion. About Our Guest: Stephen Jarvis Assistant professor London School of Economics View related content here: https://www.pnas.org/doi/10.1073/pnas.2504553122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Responding to @TimcastIRL and @The_Crucible after they aired a segment on my plural family, linked below.Should Polygamist Families be Welcome at Church? - https://richtidwell.com/should-polygamist-families-be-welcome-at-church/A Letter to the Anglican Church: https://bit.ly/PolygynyLetterOn Plural Marriage: https://richtidwell.com/on-plural-marriage/The Mia & Heis Saga: https://richtidwell.com/mia-and-heis/St. Augustine, On The Good of Marriage: https://www.newadvent.org/fathers/1309.htm"Andrew Wilson Slams Protestant Pastor For Saying Polygamy Is Biblical" - https://www.youtube.com/watch?v=9CPYbTjcUhgSTUDIES- Birthrates: https://x.com/richtidwell/status/1989109694481170715- London School of Economics and Political Science: https://www.lse.ac.uk/news/new-study-challenges-claim-polygyny-drives-men-to-civil-war- PNAS polygamy study: https://www.pnas.org/doi/10.1073/pnas.2508091122- Females outnumber men: https://www.medicaldaily.com/female-population-has-always-outnumbered-males-historically-according-our-genes-304428- More Christian women in US then men: https://www.pewresearch.org/religious-landscape-study/gender-composition/woman/- More women in the Church than men: https://www.ncls.org.au/articles/why-are-women-more-religious-than-men/
Welcome to The Sleep Edit, the podcast that helps tired kids and parents sleep better. Each week, Dr. Craig Canapari and sleep consultant Arielle Greenleaf break down evidence-based strategies you can actually use. Why are nap transitions so confusing—and why do they so often derail nights? In Part 2 of our napping series, Craig and Arielle dig into the real-world challenges families face when moving from 3→2 naps, 2→1 nap, and eventually dropping naps entirely. Using concrete examples, sleep-need math, and practical troubleshooting, this episode explains exactly what to look for and how to navigate every transition with less stress. You'll learn • How to know when it's time to drop a nap • The signs of a nap transition vs. a temporary “nap strike” • Why total 24-hour sleep matters more than wake-window charts • What typical daytime sleep looks like for infants and toddlers • The sleep math behind transitions (high vs. low sleep-need kids) • How daycare schedules can derail naps—and what parents can control • Strategies for capping naps, shifting schedules, and preventing bedtime battles • When early morning awakenings actually signal too much daytime sleep Chapters 00:00:01 — Welcome & Episode Setup 00:01:07 — The 3→2 Nap Transition: When It Starts 00:02:48 — Biology of Sleep Drive & Late Naps 00:03:43 — Why Late Bedtimes Are So Common Now 00:04:59 — How Total Sleep Needs Shape Nap Schedules 00:06:32 — Wake Windows vs. Real Sleep Need 00:07:52 — Consolidated Naps & Nap Length Targets 00:09:41 — How to Use the Third Nap as a Bridge 00:11:06 — Example: Designing a 13.5-hour Sleep Day 00:12:59 — Signs It's Time to Drop From 3→2 Naps 00:14:45 — Why Transitions Are Messy (and Normal) 00:15:56 — The 2→1 Nap Transition: Age & Signs 00:17:46 — Developmental Milestones That Disrupt Naps 00:19:06 — Case Example: Drew (13 Months) 00:20:57 — How to Start the 2→1 Transition Step-by-Step 00:22:54 — Shifting Nap Timing & Early Bedtime Strategy 00:23:56 — Tracking Sleep: Apps vs. Diaries 00:24:53 — Why Smart Monitors Often Mislead Parents 00:26:50 — When Nights Get Worse Because of Nap Issues 00:27:59 — The 1→0 Transition: What Truly Signals Readiness 00:29:18 — Daycare Nap Challenges & Parent Options 00:31:56 — Capping Naps to Protect Nighttime Sleep 00:33:30 — Nap Strikes vs. True Transitions 00:36:06 — Early Morning Awakenings & Too Much Day Sleep 00:38:30 — Final Thoughts & The Greenleaf Windows Links Napping spectacular episode 1 CIO episode of the Sleep Edit Dr. Canapari's article on Le Pause Sleep training Period of purple crying Dr. Canapari's article on napping Dr. Canapari's article on sleep needs in children Dr. Canapari articles on the science of why children stop napping Arielle's website References Paruthi, S., Brooks, L. J., D'Ambrosio, C., Hall, W. A., Kotagal, S., Lloyd, R. M., Malow, B. A., Maski, K., Nichols, C., Quan, S. F., Rosen, C. L., Troester, M. M., & Wise, M. S. (2016). Consensus statement of the American Academy of Sleep Medicine on the recommended amount of sleep for healthy children: methodology and discussion. Journal of Clinical Sleep Medicine, 12(11), 1549–1561. https://doi.org/10.5664/jcsm.6288 Spencer, R. M. C., & Riggins, T. (2022). Contributions of memory and brain development to the bioregulation of naps and nap transitions in early childhood. PNAS, 119(11), e2114326119. https://doi.org/10.1073/pnas.2114326119 Staton, S., et al. (2020). Many naps, one nap, none: A systematic review and meta-analysis of napping patterns in children 0–12 years. Sleep Medicine Reviews, 50, 101247. https://doi.org/10.1016/j.smrv.2019.101247 Galland, B. C., Taylor, B. J., Elder, D. E., & Herbison, P. (2012). Normal sleep patterns in infants and children: A systematic review of observational studies. Sleep Medicine Reviews, 16(3), 213–222. https://doi.org/10.1016/j.smrv.2011.06.001 Horváth, K. (2018). Spotlight on daytime napping during early childhood. Frontiers in Psychology, 9, 1238. https://doi.org/10.3389/fpsyg.2018.01238 Wolke, D., Bilgin, A., & Samara, M. (2017). Systematic review and meta-analysis: Fussing and crying durations and prevalence of colic in infants. The Journal of Pediatrics, 185, 55–61.e4. https://doi.org/10.1016/j.jpeds.2017.02.020 Lavner, J. A., et al. (2023). Sleep SAAF randomized clinical trial. JAMA Network Open, 6(3), e236276. https://doi.org/10.1001/jamanetworkopen.2023.6276 Paul, I. M., et al. (2016). INSIGHT Responsive Parenting Intervention and Infant Sleep. Pediatrics, 138(1), e20160762. https://doi.org/10.1542/peds.2016-0762
A giant virus associated with oyster aquaculture mortality Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Curtis Suttle and Kevin Xu Zhong explain how a previously unidentified virus may be connected to mass die-offs of farmed Pacific oysters. In this episode, we cover: • [00:00] Introduction • [01:03] Environmental virologist Curtis Suttle introduces the importance of the Pacific oyster to aquaculture. • [01:42] Suttle describes mass mortality events, including one he witnessed. • [02:42] Environmental microbiologist Kevin Xu Zhong talks about the methods used to identify the Pacific Oyster Nidovirus 1. • [03:53] Zhong describes the notable features of the nidovirus. • [05:19] Zhong and Suttle explain how the nidovirus merits designation of a nidovirus family. • [06:25] Suttle explores the takeaways for oyster farmers and regulators. • [08:15] He lists the caveats and limitations of the study. • [09:40] Conclusion. About Our Guests: Kevin Xu Zhong Research Associate University of British Columbia Curtis Suttle Professor University of British Columbia View related content here: https://www.pnas.org/doi/10.1073/pnas.2426923122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator James D. Watson dies (NY Times) Russian translation of TWiV 1024 (Medium) Canada's new budget aims to lure US researchers (Science) Bird flu surging and spreading while US agencies are asleep (npr) US slashed WHO budget, now flu surveillance is suffering globally (npr) HPV sequences in papillomas and cervical cancers (PNAS) zur Hausen Nobel Prize 2008 (Nobel) Vincent interviews zur Hausen (YouTube) Influenza virus infection, shedding, and disease in humans (J Virol) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Pandemic board game Rich – Whiskey Fungus Fed by Jack Daniel's Encrusts a Tennessee Town Alan – Rats can snatch bats out of the air and eat them Vincent – 7 basic science discoveries that changed the world Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health. Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S– Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
Swamp lights and bat sight Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore two spooky mysteries: the source of will-o'-the-wisps and how bats integrate vision with echolocation. In this episode, we cover: •[00:00] Introduction •[00:58] Richard Zare's background and expertise. •[01:26] Richard, have you ever seen will-o'-the-wisps in the wild? •[01:31] What did we already know about will-o'-the-wisps before your study? •[02:42] How could water droplets ignite methane? •[03:24] Tell us about the methods of your study. How did you explore this phenomenon? •[04:17] What are the broader implications of your findings, beyond just will-o'-the-wisps? •[05:20] What are the caveats or the limitations of the study? •[05:40] Laura Stidsholt's background and expertise. •[06:06] Laura, what can you tell us about the species you studied? •[06:25] What instruments did you attach to the bats? •[07:03] How did the bats' echolocation behavior compare in dark versus lit environments? •[08:14] What do the results suggest about the benefits of integrating information from multiple senses while hunting prey? •[08:58] What do the results imply about the potential impact of artificial light on bats? •[09:43] Final thoughts and conclusion. About Our Guests: Richard Zare Marguerite Blake Wilbur Professor of Natural Science Stanford University Laura Stidsholt Assistant Professor Aarhus University View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2521255122 https://www.pnas.org/doi/full/10.1073/pnas.2515087122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
Pendant des décennies, on a cru qu'en multipliant les compliments, on aidait les enfants à s'épanouir. « Tu es le meilleur ! », « Tu es génial ! » — autant de phrases censées nourrir la confiance. Mais selon une recherche conjointe de l'Université d'État de l'Ohio et de l'Université d'Amsterdam, publiée dans la revue PNAS, ces compliments exagérés sont en réalité un piège. Loin de renforcer l'estime de soi, ils peuvent créer des enfants égocentriques, voire manipulateurs, incapables plus tard de relations équilibrées.Tout commence souvent avec de bonnes intentions. Un parent veut encourager son enfant, surtout s'il le sent fragile ou timide. Alors il multiplie les louanges. Mais lorsqu'elles deviennent disproportionnées — quand on félicite non pas l'effort, mais la personne elle-même, en la présentant comme exceptionnelle —, le cerveau de l'enfant apprend une leçon bien différente : pour être aimé, il faut être extraordinaire. Ce n'est plus la curiosité ni la persévérance qui comptent, mais l'image que l'on renvoie.Les chercheurs ont observé que ces enfants finissent par éviter les situations où ils risquent d'échouer. L'échec, pour eux, n'est pas une étape normale de l'apprentissage, mais une menace pour l'identité flatteuse qu'on leur a imposée. Ils préfèrent donc ne pas essayer plutôt que de risquer d'être « démasqués ». Et pour continuer à mériter l'admiration, ils développent des stratégies sociales subtiles : séduire, manipuler, attirer l'attention, parfois rabaisser les autres pour se sentir supérieurs.Peu à peu, l'enfant devient dépendant du regard extérieur. Il mesure sa valeur à travers l'approbation d'autrui. Dans ce processus, une chose s'étiole : l'empathie. S'il se vit comme le centre du monde, les besoins des autres perdent de l'importance. Il ne cherche plus à comprendre, mais à convaincre ; plus à échanger, mais à briller. Ce type d'éducation, en apparence bienveillante, prépare sans le vouloir des adultes narcissiques, fragiles sous leur assurance, et incapables de tisser des liens sincères.Les chercheurs insistent : la clé n'est pas de bannir les compliments, mais de les orienter autrement. Il faut cesser de dire « Tu es incroyable » et apprendre à dire « Tu as bien travaillé ». Féliciter l'effort plutôt que le talent, reconnaître les progrès plutôt que la perfection. C'est ainsi que l'enfant apprend que la valeur ne se joue pas dans le regard des autres, mais dans l'action, la persévérance et la relation à autrui. En somme, c'est en apprenant à échouer qu'on apprend aussi à aimer. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Implications of a mutation in modern humans Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Xiangchun Ju and Svante Pääbo explore the evolutionary implications of a mutation that separates modern humans from ancestral hominins. In this episode, we cover: •[00:00] •[01:22] Neurobiologist Xiangchun Ju introduces the enzyme adenylosuccinate lyase, or ADSL, and its role in the synthesis of purine. •[02:09] Evolutionary anthropologist Svante Pääbo talks about the discovery of the A429V mutation, which is present in modern humans but not Neanderthals or Denisovans. •[03:38] Ju and Pääbo talk about the methods to humanize mice in order to study the evolutionary importance of the A429V mutation. •[05:04] They explain the results of the behavioral studies of the humanized mice. •[06:27] Pääbo explores the takeaways from the study. •[08:05] He contextualizes the study alongside other studies of modern human development. •[09:17] Pääbo and Ju list the caveats and limitations of the study. •[10:14] Conclusion. About Our Guests: Xiangchun Ju Postdoctoral scholar Okinawa Institute of Science and Technology Svante Pääbo Director Max Planck Institute for Evolutionary Anthropology View related content here: https://www.pnas.org/doi/10.1073/pnas.2508540122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
In this solo episode, Darin pulls back the curtain on one of the most important parts of his life: he prepares for travel. From the supplements that keep his immune system strong to hydration hacks, adaptogenic elixirs, and EMF protection, this episode is a masterclass in staying grounded and resilient on the road. Travel doesn't have to destroy your health — it can actually elevate it. With a few intentional rituals, smart packing, and awareness, you can turn every trip into an opportunity to deepen your energy, focus, and connection to yourself. What You'll Learn 00:00:00 – Why travel is stressful and how to transform it into an empowering, health-boosting experience 00:01:00 – Darin's supplement protocol: Vitamin D3/K2, probiotics, zinc, vitamin C, and glutathione for immune defense 00:03:00 – The antioxidant power of glutathione and why it's critical for long flights and radiation exposure 00:04:30 – How CBD and terpenes support stress resilience and circadian rhythm through the endocannabinoid system 00:05:20 – Why magnesium and NAD are the unsung heroes of travel recovery and energy 00:06:30 – Darin's morning elixir recipe: cacao, guarana, ashwagandha, chaga, ginseng, and monk fruit 00:08:00 – Hydration 101: how to use a manual RO filter, mineralize your water, and ditch plastic 00:10:00 – How to build nutrient density into travel days using chlorella, spirulina, Shakeology, and Barukas 00:12:00 – Travel nutrition sovereignty: packing your own snacks, fasting, and avoiding airline food 00:14:00 – Movement anywhere: Darin's “portable gym” using bungee cords and bodyweight routines 00:16:00 – The 3-hour morning ritual: NewCalm, Healing Codes, journaling, cacao, red light therapy, and breathwork 00:20:00 – How to avoid radiation scanners, mitigate EMFs, and use WaveGuard for energy field protection 00:22:00 – Why Darin microdoses nicotine for cognitive focus and immune modulation 00:23:00 – Breathing practices for immune strength: 3–4 rounds of 40 deep breaths, Wim Hof style 00:24:00 – How to pack fruit and salads in mason jars to stay hydrated and nourished on planes 00:26:00 – Grounding after flights: barefoot on the earth, morning sunlight, and re-aligning your circadian rhythm Thank You to Our Sponsors Manna Vitality: Go to mannavitality.com/ or use code DARIN20 for 20% off your order. Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway “Preparation is sovereignty. When you take responsibility for your nutrition, your hydration, and your energy before you travel, you're no longer surviving the trip — you're expanding through it.” Bibliography Martineau AR et al. Vitamin D supplementation to prevent acute respiratory infections: systematic review. BMJ. 2017. Goldenberg JZ et al. Probiotics for prevention of respiratory infections. Cochrane Database. 2017. Hemilä H. Vitamin C and zinc in common cold. Nutrients. 2017. Blessing EM et al. Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics. 2015. Morris HJ et al. Spirulina and chlorella as functional foods. Nutrients. 2022. Longo VD, Panda S. Fasting, circadian rhythms, and time-restricted feeding. Cell Metabolism. 2016. Booth FW et al. Waging war on physical inactivity. J Physiol. 2017. Balmori A. Electromagnetic pollution from radiofrequency fields. Pathophysiology. 2015. Kox M et al. Voluntary activation of sympathetic nervous system and attenuation of the innate immune response. PNAS. 2014.
Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Floss-based vaccination (Nat Biomed Engineering 2025) Press article on Floss-based vaccine paper (Sci News) Human milk IgA promotes immune development (PNAS 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
Where primates evolved Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Jorge Avaria-Llautureo and Chris Venditti explain why the evolution of primates likely occurred in cold, dry climates rather than in tropical forests. In this episode, we cover: •[00:00] Introduction •[00:58] Evolutionary biologist Jorge Avaria-Lautureo explains the prevailing hypothesis that primates evolved in a tropical climate •[02:54] Evolutionary biologist Chris Venditti introduces evidence suggesting a different origin climate. •[03:54] Avaria discusses how the researchers reconstructed the climate of early primate species. •[05:05] Venditti and Avaria explain why it was important to use standardized climate definitions in this study. •[07:29] Avaria describes the results of the study. •[08:18]Venditti talks about the importance of understanding early primates' climates. •[09:21] Avaria and Venditti talk about the study's caveats and limitations. •[10:22] Conclusion. About Our Guests: Jorge Avaria-Llautureo Postdoctoral scholar University of Reading Chris Venditti Professor University of Reading View related content here: https://www.pnas.org/doi/10.1073/pnas.2423833122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
In our wonderful interview, Dr. Danna Trachtenberg Zeiger and I celebrate her debut picture book, Rewriting the Rules, a STEM nonfiction picture book which was just released from Millbrook Press (Carol Hinz, editor) on September 9, 2025". She is represented by Gaby Cabezut at The Seymour Agency. A published scientist, Danna's research has appeared in top scientific journals such as Science, Neuron, and PNAS. Formerly a biology professor and program director at Fisher College, she now focuses on writing for children. In our conversation Danna describes her transition from scientist to author, and the benefits that a career in science can bring to the writer's table. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
5—6—3—4—3—1—7—2In the first episode under our new podcast name (it's now the Science Fictions podcast!), we ask whatever happened to all those games that claimed to tell you your “brain age”—games that turned into a whole scientific literature on brain training. We discuss: the still-unresolved question of whether training one specific cognitive ability makes you generally smarter; seemingly endless contrasting meta-analyses; and the small matter of what brain training might tell us about the nature of intelligence.(If you can repeat the list of numbers from the top in reverse order then you have the brain of a 25-year-old. If you're 25 or younger, then I don't know what to tell you.)We're now an official part of the Works in Progress podcast world. You can find their other podcasts, including Hard Drugs, the one we talked about on today's episode (about the remarkable development of a drug for HIV), at podcast.worksinprogress.co. Show notes* The 2008 PNAS paper that started the craze for working memory training* The under-discussed rebuttal* 2013 meta-analysis concluding there's no evidence for far transfer* 2015 meta-analysis concluding there is no convincing evidence brain training is effective* 2016 meta-analysis saying there is no convincing evidence brain training is NOT effective* Very useful and detailed 2016 review of the evidence and the methodological issues inherent in brain training (including active vs. passive control groups)* 2020 meta-meta-analysis arguing that the active-passive distinction doesn't matter* 2023 review criticising the meta-meta-analysis* And the authors' own 2020 meta-analysis* 2022 meta-analysis of commercial brain training in older peopleCreditsThe Science Fictions podcast is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit sciencefictionspod.substack.com/subscribe
Climate change and lake oxygenation Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Joachim Jansen explains how climate change altered cycles of oxygenation in lakes. In this episode, we cover: •[00:00] Introduction. •[00:56] Limnologist Joachim Jansen introduces us to the cycles of oxygenation in lakes throughout the seasons. •[02:35] He describes previous hypothesis about climate change and lake oxygenation and introduces the methods and datasets of the study. •[04:59] Jansen introduces the results of the study, including key differences between large and small lakes. •[06:54] He talks about the consequences of deoxygenation. •[09:03] Jansen explains the caveats and limitations of the study. •[09:37] Conclusion. About Our Guest: Joachim Jansen Postdoctoral Researcher University of Helsinki View related content here: https://www.pnas.org/doi/10.1073/pnas.2426140122 Follow us on Spotify, Apple Podcasts, or wherever you get your podcasts for more captivating discussions on scientific breakthroughs! Visit Science Sessions on PNAS.org: https://www.pnas.org/about/science-sessions-podcast Follow PNAS: Twitter/X Facebook LinkedIn YouTube Sign up for the PNAS Highlights newsletter
What if our memories weren't fixed, but flexible? And what if the key to understanding fear, emotion, and consciousness lies in how the brain constantly reshapes experience?In this episode of Mind-Body Solution, Dr Tevin Naidu speaks with Prof Daniela Schiller, a world-renowned neuroscientist, and director of the Laboratory of Affective Neuroscience at Mount Sinai. Prof Schiller's groundbreaking work explores how we form, change, and even reimagine emotional memories, from the neuroscience of fear to the dynamic nature of consciousness and identity. Together, we dive into:- How fear memories are formed in the brain- Why emotional responses are flexible, not hardwired- The ethics of modifying traumatic memories- Social navigation: how the brain maps human relationships- The Human Affectome: a bold framework linking emotion and consciousness- Can machines ever be conscious? Free will, probabilities, and neuroscience- Memory as liberation: how to live with multiple stories of the selfProf Schiller is not only a world-leading neuroscientist with work published in Nature, Neuron, Nature Neuroscience, and PNAS, she's also a Fulbright Fellow, Kavli Frontiers of Science Fellow, two-time Moth StorySLAM winner, and drummer for the rock band "The Amygdaloids".TIMESTAMPS:(0:00) – Introduction: Daniela Schiller on the Science of Emotion & Memory(0:39) – From Animal Models to Human Fear Studies: Schiller's Journey(2:00) – What Happens in the Brain When a Fear Memory is Formed?(3:15) – Flexibility of Emotional Responses: Why Fear Is Not Hardwired(4:51) – Computational Psychiatry & the Brain as an Algorithmic System(6:00) – From Circuits to Consciousness: Can Neuroscience Explain Subjective Experience?(7:11) – The Human Affectome: A Framework Linking Emotion and Consciousness(9:13) – What Is Consciousness? Felt Experience as the Core of Mind(11:04) – Social Navigation: Mapping Human Relationships in the Brain(14:02) – How Social Media Distorts Real Interaction and Social Space(18:15) – Ethics of Modifying Traumatic Memories: Liberation or Risk?(21:27) – Are Emotions Brain Events, Bodily Events, or Psychological Phenomena?(23:16) – The 4E Approach: Embedded, Embodied, Enactive, and Extended Cognition(24:00) – Bringing Philosophy Into Neuroscience: The Human Affectome Project(27:03) – Exciting Advances: Intracranial Recordings, VR, and Naturalistic Neuroscience(33:11) – Can Artificial Intelligence or Machines Ever Be Conscious?(36:26) – Free Will and Probabilities: Neuroscience Meets Philosophy(41:12) – Overcoming Fear as Liberation: Redefining Memory and Identity(46:09) – Living With Multiple Stories: Memory, Authenticity, and Self-Creation(1:02:24) – Future Directions: Reconsolidation, Social Space, and the Human AffectomeEPISODE LINKS:- Daniela' Website: https://profiles.mountsinai.org/daniela-schiller- Daniela's Lab: https://labs.neuroscience.mssm.edu/project/schiller-lab/- Daniela's Publications: https://www.ncbi.nlm.nih.gov/myncbi/daniela.schiller.2/bibliography/public/CONNECT:- Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution- YouTube: https://youtube.com/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
Inflammation is the body's natural way of healing, but when it becomes chronic and hidden, it quietly drives many of today's most common health problems—heart disease, diabetes, dementia, cancer, autoimmune conditions, and more. Unlike the redness and swelling from a cut or sprain, this “silent inflammation” often goes unnoticed while slowly damaging tissues and speeding up aging. Modern life fuels the fire: processed foods, food additives, pollution, plastics, chronic stress, too much sitting, and poor sleep. The good news is inflammation can be calmed by simple daily choices—eating colorful whole foods like berries, leafy greens, beans, nuts, seeds, and omega-3 rich fish; adding herbs and spices like turmeric and cumin; moving regularly; practicing relaxation; and repairing gut health. Even small shifts, like climbing stairs, eating within a shorter window, or reducing sugar, can make a big difference. By lowering inflammation, the body finds balance again, opening the door to more energy, resilience, and healthy aging. In this episode, I discuss, along with Dr. Shilpa Ravella and Dr. David Furman, why it's important to be aware of systemic inflammation and how to address it. Dr. Ravella is a gastroenterologist and Assistant Professor of Medicine at Columbia University Medical Center. She is the author of A Silent Fire: The Story of Inflammation, Diet & Disease, which investigates inflammation—the hidden force at the heart of modern disease. Her writing has appeared in The Atlantic, New York Magazine, The Wall Street Journal, TIME, Slate, Discover, and USA Today, among other publications. Dr. David Furman is Associate Professor and Director of the Bioinformatics Core at the Buck Institute for Research on Aging, as well as the Director of the Stanford 1000 Immunomes Project. He obtained his doctoral degree in immunology from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans. He has published nearly thirty scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:What Causes Inflammation And How Can You Treat It? The Silent Killer: Inflammation And Chronic Disease How Silent Inflammation Accelerates Aging
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