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Note: This episode originally aired in October 2022. Dr. Chris Mason, professor at Weill Cornell Medicine, as he tells the story of his collaboration with NASA on the famous Twins Study and its implications for the future of human health, genetics, and interplanetary travel. During this episode you'll learn about: 1. Dr. Chris Mason, professor of Physiology and Biophysics at Weill Cornell Medicine [00:00:53] 2. Dr. Mason's first research mission with NASA [3:48] How space and gravity affected astronaut Scott Kelly [4:28] What is genetic malleability? [8:54] 3. How many genes do humans have? [10:14] The cost to test a whole genome [12:39] 4. Thorne's Biological Age Test, modifying your own genetic expression with lifestyle changes [16:01] 5. Concern over the scientific possibility of altering genetic expression with technology [18:52] 6. Questions from the community [23:38] How sterile are the inside of spaceships, and is there such thing as being “too clean” for astronauts? [23:45] Is space itself sterile? [26:03] What TV show most accurately depicts life in space? Space nutrition? [27:11] Do people age at different rates because they're in space, and can supplements impact how people age? [29:51] When are humans going to Mars, and how will we get our nutrition there? [34:24] What has the space program taught us about the value of supplements? Do astronauts take them now? [35:46] Are astronauts getting less nutrition from the dehydrated foods they eat? [36:53] Will humans find a mineral in space that could someday be used for human health? [38:07] Is there intelligent life out in space? [39:27] Resources to topics mentioned in this episode: GENCODE One Giant Leap: What Space Travel Has Taught Us About Health on Earth Research Extracts: NASA's Twins Study | PCOS and Microbiome | Blueberries for Pain Reduction How Does Thorne's Biological Age Test Work? What's Your Actual Age? Chronological vs. Biological Age Assess Your Biological Age With Thorne's Biological Age Health Panel Why It's Important to Take Methylate While Taking Nicotinamide Riboside What Can a Microbiome Test Tell You That a Genetic Test Can't? From the podcast archive: Onegevity with Joel Dudley and Chris Mason What You'll Learn From Biological Age Testing How to Solve an Age-Old Problem, with Dr. Lee Hood Products mentioned in this episode: Biological Age Health Panel, FloraMend Prime Probiotic®, Prebiotic +, Niacel® 400, Gut Health Test with Microbiome Wipe Subscribe To More Content Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne's Take 5 Daily blog. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Dr. Doug Lucas and Dr. Ashley Lucas take a deeper look at the recent Netflix Docu-series, You Are What You Eat. This documentary is based on a Twins study. Dr. Doug and Dr. Ashley unpack the data and compare it to the messaging from the series. INTERESTED IN OUR HEALTHSPAN PROGRAM? Click here: https://bit.ly/HealthSpanNation Optimal Human Health: https://bit.ly/optimalhumanhealth ======================== The Dr Doug Show is a podcast designed to help you maximize HealthSpan and live Better, Longer. Complex health topics are broken down into easy to digest episodes that cover controversial areas such as hormones, peptides, pharmaceuticals and mindset. Dr Doug's mission is to help YOU aim for Optimal Not Average while escaping the traps built into our modern culture and society. ABOUT DR. DOUG LUCAS ======================== Dr Doug Lucas is a double board certified, Stanford trained, anti-aging specialist and orthopedic surgeon. He left the traditional medical model to create his two companies Optimal Human Health MD and Optimal Bone Health MD where he and his team of experts go above and beyond the expectations of most doctors and help patients to achieve the health goals of their dreams! Douglas Lucas, DO Board Certified Anti-Aging and Regenerative Medicine Fellow Anti-Aging and Metabolic Medicine Board Certified Orthopedic Surgeon CONNECT WITH DR. DOUG LUCAS ON SOCIAL ======================== Instagram: https://www.instagram.com/dr_douglucas/ Facebook: https://www.facebook.com/DrDougLucas/ Linkedin: https://www.linkedin.com/in/doug-lucas-b0243522/
Tuesday, December 13th — In this episode we talk about: More Christmas movie talk Weather report: Chicken Run sequel, documentary about vegan vs. omnivore twins study coming to Netflix The Secret to Getting People to Eat More Plant-Based Food (https://www.washingtonpost.com/climate-solutions/2023/12/12/vegan-food-label-diet/) Going Vegan for Your New Year's Resolution? Here are 4 Things You Should Know (https://plantbasednews.org/lifestyle/food/vegan-new-years-resolution/) 27 Vegan Gifts for the Plant-Forward Friends on Your List (https://www.goodhousekeeping.com/holidays/gift-ideas/g45193456/best-vegan-gifts/) And more! Tune in live every weekday at 11am to watch on YouTube or on Instagram (@plantbasedmorningshow and @nomeatathlete_official), or watch on Twitter or Twitch! Follow @plantbasedmorningshow, @realmattfrazier, and @itsdoughay for more.
Mike talk about his vegan experience at the Golden Coral. Jason talks about the new Kraft boxed vegan mac and cheese. They also discuss the breakthrough study of twins and diet that validates the positive impact a vegan diet provides.
Continuous glucose monitoring can be a powerful tool for gaining real-time insights into how diet, lifestyle habits, and the many decisions we make daily affect our health. Retired astronaut Scott Kelly tried a CGM for a month and shares his personal insights. Scott Kelly and Josh Clemente discuss how CGM can be used to effect habit change, what Kelly's participation in the unique NASA Twins study was like and what was learned, and insights Kelly gleaned about society and the environment while viewing Earth from space.
Genetic differences among students are the single biggest influence on literacy and numeracy but students attending private schools make no more progress from years 3 to 9 than students attending public schools.
Genetic differences among students are the single biggest influence on literacy and numeracy but students attending private schools make no more progress from years 3 to 9 than students attending public schools.
Launch into outer space with Dr. Chris Mason, professor at Weill Cornell Medicine, as he tells the story of his collaboration with NASA on the famous Twins Study and its implications for the future of human health, genetics, and interplanetary travel. During this episode you'll learn about: Chris Mason, professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine and co-founder of Onegevity [00:00:53] Mason's first research mission with NASA [3:48] How space and gravity affected astronaut Scott Kelly [4:28] What is genetic malleability? [8:54] How many genes do humans have? [10:14] The cost to test a whole genome [12:39] Thorne's Biological Age Test, modifying your own genetic expression with lifestyle changes [16:01] Concern over the scientific possibility of altering genetic expression with technology [18:52] Questions from the community [23:38] How sterile are the inside of spaceships, and is there such thing as being “too clean” for astronauts? [23:45] Is space itself sterile? [26:03] What TV show most accurately depicts life in space? Space nutrition? [27:11] Do people age at different rates because they're in space, and can supplements impact how people age? [29:51] When are humans going to Mars, and how will we get our nutrition there? [34:24] What has the space program taught us about the value of supplements? Do astronauts take them now? [35:46] Are astronauts getting less nutrition from the dehydrated foods they eat? [36:53] Will humans find a mineral in space that could someday be used for human health? [38:07] Is there intelligent life out in space? [39:27] Resources to topics mentioned in this episode: GENCODE One Giant Leap: What Space Travel Has Taught Us About Health on Earth Research Extracts: NASA's Twins Study | PCOS and Microbiome | Blueberries for Pain Reduction How Does Thorne's Biological Age Test Work? Why It's Important to Take Methylate While Taking Nicotinamide Riboside What Can a Microbiome Test Tell You That a Genetic Test Can't? Episode 10: Onegevity with Joel Dudley and Chris Mason Links to products mentioned in this episode: Biological Age Health Panel, FloraMend Prime Probiotic®, Prebiotic +, Niacel® 400, Gut Health Test with Microbiome Wipe Subscribe To More Content Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne's Take 5 Daily blog. * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Brad West will have to eat the same food, do the same exercise, contain and restrict his social circles, conduct similar experiments, tasks, and basically copy everything his twin brother Brent will do…while in space…for more than 500 days… simulating the same amount of time it will take for humans to get to Mars- and helping to prepare humans to explore Mars. Why would Brad and Brent do this? It's all part of the proposed “Twin Orbit Study” that you're about to discover right here, on the Casual Space Podcast. The commercialization of space (SpaceX, Axiom Space, Blue Origin) brings new opportunities to study astronauts, including identical twins, on industry‐led space stations with unprecedented detail. Extremely long‐duration microgravity will be the new normal when we travel into deep space, starting with Mars, and our success will be a test of health endurance in several respects. First, given the great distances, there will be very limited support from Earth once the mission begins. Second, the space weather (and radiation) is an order of magnitude more challenging. Third, the behavioral and cognitive challenges for such long missions will place an unprecedented strain on the crew. Although NASA, ESA, JAXA, ROSCOSMOS, and others are building a large knowledge base to address these challenges through missions on the International Space Station, very few crew have been studied in weightlessness for durations over six months, and more data from longer missions is critically needed. Which makes for a perfect opportunity for The Twin Orbit study team, who are proposing a brand new, long‐duration Twins Study (building from the NASA Twins Study), and will work to accomplish four main goals: Conduct Scientific Research for Biomedical Discovery and Testing New Hypotheses Develop and Deploy New Technologies for Crew Health and Mission Maintenance Develop Crew Health Operating Procedures Applicable for Long‐duration and Deep Space Missions Inspire the Next Generation of Explorers Learn More About Twin Orbit here: https://www.twinorbit.com/ About Brent West, in his own words: “It was the Cosmos TV series that initially captured my interest...I saw the first episode in high school in the late 1980's, and since that time I have always been fascinated with all-things space. I knew I wanted to be an astronaut after I saw the movie Apollo 13 in the summer of 1995. I focused on my purpose and what I wanted to do and be involved with. At the time, I was a young LTjg (Lieutenant Junior Grade) onboard my first submarine, USS PINTADO (SSN-672). Brent West, Commander, U.S. Navy, earned his master's degree in Aerospace Engineering from University of Michigan in 2001 and worked in the Space Physics Research Laboratory as a student research assistant to help design a small student-led satellite project. Brent also worked as a flight controller at Johnson Space Center from 2001 – 2003 in ECLSS (Environmental Control and Life Support Systems and earned his PhD in Physics from George Mason University in 2012, studying X-ray pulsars. About Brad West: Brad West graduated from Winnebago High School in Winnebago, Illinois in 1990. He attended Illinois State University where he received his Bachelor of Science degree in sociology in 1994 and a Master of Science degree in education administration in 1996. Soon after receiving his master's degree, Brad moved to Richmond, Virginia to work as a Career Systems Manager/Advisor at Virginia Commonwealth University. He moved to Orlando, Florida in the spring of 1998, at the behest of a best friend who was working at Disney, and took employment in information technology at the Universal Orlando Resort. He loved the atmosphere and the energy of Universal and Orlando and worked there until the spring of 2004.Brad was accepted into the Doctor of Philosophy program in Higher Education Administration at the University of Florida in 2004. Upon starting the program, he worked as a graduate assistant in the Graduate School under the supervision of Associate Dean of the Graduate School. There, he became enamored with the many fields of graduate and doctoral education. After finishing program coursework, he worked several years in information technology at the University of Florida. Doctoral candidacy followed, and ultimately obtained a PhD in Higher Education Administration in 2013 with a focus on factors that influence doctoral time-to-degree in graduate education. Today, Brad is living in Southern Florida and working in information technology for a large national health care system. He enjoys traveling, visiting friends in the Florida keys, music, sports, anything NASA, and meeting new people. About Chris Mason Dr. Christopher E. Mason is a geneticist and computational biologist who has been a Principal Investigator and Co-investigator of many NASA missions and projects. He is a Professor at Weill Cornell Medicine, with affiliate appointments at the Meyer Cancer Center, Memorial Sloan Kettering Cancer Center, the Information Society Project (ISP) at Yale Law School, and the Consortium for Space Genetics at Harvard Medical School. Here's what to do next: Check out Chris's new book; The Next 500 Years: Engineering Life to Reach New Worlds https://www.amazon.com/Next-500-Years-Engineering-Worlds/dp/0262543842/ref=asc_df_0262543842/?tag=hyprod-20&linkCode=df0&hvadid=533430521017&hvpos=&hvnetw=g&hvrand=10374932519418788990&hvpone=&hvptwo=&hvqmt=&hvdev=c&hvdvcmdl=&hvlocint=&hvlocphy=1028099&hvtargid=pla-1424157036884&psc=1 Reach out here with questions; info@twinorbit.com
Today is the UK Space Agency Mars Day, it celebrates the 6th anniversary of the launch of the first ExoMars mission, and a year since NASA's Perseverance rover started exploring Mars. In just three years' time NASA aims to return humans to the Moon as part of the Artemis Mission, and in just a decade it's onward to the surface of Mars – the tech and engineering may be ready, but are we? Being in space has well-documented negative effects on the body. But the effect of being in space on the brain has been studied less. In this podcast Dr Yvonne Couch, ARUK Research Fellow at University of Oxford hosts a discussion with three world leading experts to explore the effects of space travel on the brain. We're joined by Chris Mason, Professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine, USA. Chris is one of the people behind the landmark Twins Study that followed identical twins Scott and Mark Kelly, while one spent a year on earth and the other spent a year in space – he works with NASA, runs multiple labs, and utilises computational and experimental methodologies to identify and characterise the essential genetic elements that guide the function of the human genome, with a particular emphasis on the elements that orchestrate the development of the human brain. Chris has also written a fantastic book ‘The Next 500 Years' about our future in space. Next we have Dr Iya Whiteley, Space Psychologist and Director of the Centre for Space Medicine at Mullard Space Science Laboratory, at University College London. Dr Whiteley works with the European Space Agency is a trained Astronaut Instructor and has published several papers about fatigue in astronauts. She helps develop tools to support crew autonomous operations in complex human spacecraft and works at the cutting edge of psychological support of astronauts going to the moon and mars. Iya is also the author of a new book titled “Toolkit for a Space Psychologist - to support astronauts in exploration missions to the Moon and Mars” Last by far from least we have the unstoppable Henrik Zetterberg, Professor of Neurochemistry and neurodegenerative disease expert at University College London and the University of Gothenburg. Henrik is a leading expert in fluid based biomarkers in dementia, and in 2020 he discovered a new method to detect the disease about two decades before significant symptoms are present. In this show he does an amazing job of keeping the show on track as we explore radiation, gravity, psychology, food, sleep and everything that makes astronauts ‘Super Human', or are they? The Next 500 Years – https://amzn.to/3t2iCV1 Toolkit for a Space Psychologist – https://amzn.to/3CGmTAE Twins Study - https://www.nasa.gov/twins-study More on Mars Day - https://marsday.org.uk/ -- You can find out more about our guests, and access a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more https://www.dementiaresearcher.nihr.ac.uk This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.
This Week: Time Crystals, HIV Cured?, Sex Ed, AI Fashion Maps, Extreme Life, Heart Fish, Venom Resistant Birds, Animal Optimism, Bacteria & Fatigue, Caloric Restriction, Clutter Or Enrichment?, MS Twins Study, And Much More... The post 16 February, 2022 – Episode 863 – How to Make A Time Crystal appeared first on This Week in Science - The Kickass Science Podcast.
This episode continues our series of episodes on space biology and #SpaceOmics with Dr. Tejaswini Mishra. Dr. Mishra introduces The NASA Twins Study, a cornerstone scientific work where two twin astronauts were monitored, with one twin traveling to space, and one staying on earth. Dr. Mishra explains the importance of studying long term spaceflight missions, how The NASA Twins Study was set up in a particularly great way to study spaceflight impact, the many different types of data collected and analyzed, and some of the results found by the study. During the episode, Dr. Mishra explains many of the types of data collected such as microbiome and telomere data. After covering the types of data, we explore some of the main results such as the first ever test of a vaccination in space. Dr. Mishra then explains more in depth on changes seen during spaceflight such as telomere length, gene expression, DNA damage, cognitive function, and more. We discuss how concerning the various changes that occur in space could be for astronauts, such as becoming hypoxic. Dr. Mishra also explains pointers to the kinds of things we should focus on when we go deeper into space for understanding the impact on the human body. Finally, we summarize the main messages of the paper and hear Dr. Mishra's thoughts on the future of space research. The NASA Twins Study can be found at: https://science.sciencemag.org/content/364/6436/eaau8650
Professor Susan Bailey from CSU's Department of Environmental & Radiological Health Sciences joins us to discuss her project with the NASA Twins Study, an investigation of identical twin astronauts Scott and Mark Kelly that aims to identify factors in spaceflight that influence human health in preparation for human space exploration to the Moon or Mars.Bailey tells us what her study reveals about aging in space, particularly how telomeres, the caps of our chromosomes, change with spaceflight — and what this means for aging on Earth and in orbit.Read about Bailey's preliminary findings on telomeres in space here.Find the Twins Study' scientists first publication in Science here.Read the latest update on "The Biology of Spaceflight," a package of papers from 200 NASA Twins Study investigators, published in Cell Press in November 2020, here.
What does it take to be an astronaut? Neil deGrasse Tyson, Gary O’Reilly, and Chuck Nice break down the physical effects of being in space and the results of the astronaut twins study with guests astronaut Scott Kelly and biophysicist Chris Mason. NOTE: StarTalk+ Patrons can watch or listen to this entire episode commercial-free here: https://www.startalkradio.net/show/the-right-stuff-with-astronaut-scott-kelly-and-dr-chris-mason/ Thanks to our Patrons Jamie Ferns, evan stegall, Payton Hawk, Farid El Nasire, Steve Lindauer, Austin Lawrence, Cory Farnum, Nathan Mills, Trumpet Wom', and Noah for supporting us this week. Photo Credit: NASA. See omnystudio.com/listener for privacy information.
The Twins Study was the first biomolecular view into how the human body responds to spaceflight.
In an unprecedented sharing of discovery, 84 researchers have released their key findings from NASA’s landmark Twins Study.
In questa puntata parliamo dello studio che la NASA ha condotto monitorando il DNA di due astronauti gemelli, Scott e Mark Kelly per stabilire come la permanenza nello spazio possa influire sul DNA umano. A farci compagnia ci sono i Fantastici 4, che hanno ottenuto i loro superpoteri proprio in seguito a una disavventura spaziale.
Dr. John Charles spent nearly 33 years at NASA—most recently as Chief Scientist of the Human Research Program—working on human spaceflight through Shuttle, Mir, ISS, and beyond. He lead missions such as STS-95 (John Glenn’s Shuttle flight), STS-107, and the Twins Study with Scott and Mark Kelly. He retired from NASA in February 2018 and is now the Scientist in Resident at Space Center Houston. We talk about his career, the human spaceflight issues he worked and solved in his time at NASA, and the things that need to be solved for the exploration of the Moon, Mars, and beyond. This episode of Main Engine Cut Off is brought to you by 39 executive producers—Kris, Pat, Matt, Jorge, Brad, Ryan, Jamison, Nadim, Peter, Donald, Lee, Jasper, Chris, Warren, Bob, Russell, John, Moritz, Joel, Jan, David, Grant, Mike, David, Mints, Joonas, Robb, Tim Dodd the Everyday Astronaut, Frank, Rui, Julian, Lars, Heather, and six anonymous—and 238 other supporters on Patreon. AstroCryptoTriviology, John’s Blog About John John Charles (@csm014) | Twitter Human Research Program | NASA Email your thoughts, comments, and questions to anthony@mainenginecutoff.com Follow @WeHaveMECO Listen to MECO Headlines Join the Off-Nominal Discord Subscribe on Apple Podcasts, Overcast, Pocket Casts, Spotify, Google Play, Stitcher, TuneIn or elsewhere Subscribe to the Main Engine Cut Off Newsletter Buy shirts and Rocket Socks from the Main Engine Cut Off Shop Support Main Engine Cut Off on Patreon Music by Max Justus
Dr. Andy Feinberg and Dr. Steve Platts discuss the history and details behind the Twins Study. The experts reveal some of the findings from the multi-year endeavor packed with 10 different investigations. HWHAP Episode 87.
Dr. Andy Feinberg and Dr. Steve Platts discuss the history and details behind the Twins Study. The experts reveal some of the findings from the multi-year endeavor packed with 10 different investigations. HWHAP Episode 87.
Dr. Andy Feinberg and Dr. Steve Platts discuss the history and details behind the Twins Study. The experts reveal some of the findings from the multi-year endeavor packed with 10 different investigations. HWHAP Episode 87.
The news to know for Friday, April 12th, 2019! Today, what to know about the arrest of the WikiLeaks founder, and why a top medical association is pushing back against a new military policy. Plus: the results from the NASA twins study, who else is listening when you talk to Alexa, and get ready for Game of Thrones... Those stories and many more in less than 10 minutes! Award-winning broadcast journalist and former TV news reporter Erica Mandy breaks it all down for you. Head to www.theNewsWorthy.com to read more about any of the stories mentioned under the section titled 'Episodes' or see sources below... Today's episode is brought to you by Zola. Start your free wedding website at www.Zola.com/newsworthy Become a NewsWorthy Insider! Click here: https://www.theNewsWorthy.com/insider Sources: Assange Arrested: CBS News, AP, BBC, NYT Transgender Troops: AP/Time, PBS National Enquirer for Sale: NYT, CNN, Fox Business NASA Twins Study: Gizmodo, NYT, USA Today Alexa Listening: CNN, Bloomberg Uber IPO: CNBC, TechCrunch Samsung Galaxy Fold: USA Today, CNET Disney+ Update: Variety Game of Thrones: Deadline, Variety Coachella: Billboard, E News, LA Times
In this episode, we continue our interview with John Charles on a number of MOL topics, including tying up the discussion on MOL artwork from part 1, the declassification of MOL materials, and the legacy of MOL—including some time devoted to paying respects to Robert Lawrence, a so-called “Hidden Figure” from the MOL Air Force pilot corps.Check out John's page with information on MOL, including articles he has written and a section devoted to MOL art: http://www.astrocryptotriviology.com/mol-artJohn also makes mention of author Megan Prelinger… check out her book entitled, “Another Science Fiction: Advertising the Space Race 1957-1962.”This is Part 2 of our Manned Orbiting Laboratory interview.Note: apologies for some noise distortion with Emily Carney's voice; our VOIP system for recording podcasts is, at best, imperfect! We apologize in advance for the quality of portions of the recording.++++++++++++++++John Charles was a long-time NASA life scientist and science manager with a life-long interest in spaceflight history. He retired from NASA on February 22, 2018, after nearly thirty-three years in a career that started as a cardiovascular investigator on Space Shuttle flights, spanned Mir missions and the Shuttle flight of John Glenn, included overseeing the joint US/Russian one-year mission on ISS and the Twins Study, and peaked as the Chief Scientist of NASA's Human Research Program, guiding NASA biomedical research on the International Space Station in preparation for sending astronauts to Mars.John is now the first scientist-in-residence at Space Center Houston, the official visitors center of the Johnson Space Center, and an emeritus employee of the Johnson Space Center mentoring younger scientists. He is an Adjunct Professor of Kinesiology at Texas A&M University. He and his wife Kathy own ACT4space, LLC, a private outreach, education, research, and consulting business.In addition, John is applying his decades of experience in space biomedical research and oversight to understanding the human health and performance aspects of the Manned Orbiting Laboratory, a cancelled program by the U.S. Air Force and the National Reconnaissance Office to put military astronauts into low Earth orbit to conduct detailed observations of Soviet and Chinese capabilities during the Cold War.
In this episode, we'll learn how John Charles became interested in the Manned Orbiting Laboratory in the first place, and then we'll spend some time discussing the art of MOL.Check out John's page with information on MOL, including articles he has written and a section devoted to MOL art: http://www.astrocryptotriviology.com/mol-artThis is Part 1 of our Manned Orbiting Laboratory interview.++++++++++++++++John Charles was a long-time NASA life scientist and science manager with a life-long interest in spaceflight history. He retired from NASA on February 22, 2018, after nearly thirty-three years in a career that started as a cardiovascular investigator on Space Shuttle flights, spanned Mir missions and the Shuttle flight of John Glenn, included overseeing the joint US/Russian one-year mission on ISS and the Twins Study, and peaked as the Chief Scientist of NASA's Human Research Program, guiding NASA biomedical research on the International Space Station in preparation for sending astronauts to Mars.John is now the first scientist-in-residence at Space Center Houston, the official visitors center of the Johnson Space Center, and an emeritus employee of the Johnson Space Center mentoring younger scientists. He is an Adjunct Professor of Kinesiology at Texas A&M University. He and his wife Kathy own ACT4space, LLC, a private outreach, education, research, and consulting business.In addition, John is applying his decades of experience in space biomedical research and oversight to understanding the human health and performance aspects of the Manned Orbiting Laboratory, a cancelled program by the U.S. Air Force and the National Reconnaissance Office to put military astronauts into low Earth orbit to conduct detailed observations of Soviet and Chinese capabilities during the Cold War.
In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 2 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences.
In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 1 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired from NASA in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences
In this episode of Space 3D, the co-hosts speak with John Charles of NASA's Johnson Space Center about the medical capabilities of the space program. Topics covered include women in space, cosmic hygiene, the importance of posture, astronaut exercise equipment, physiologic adaptations of age and more!This is part 3 of our interview with Dr. John Charles.+++++++++++++++++++++++++++++John Charles, PhD was a child of the early space age, and clearly remembers playing “John Glenn” while lying on his back in the dusty playground of his elementary school, in the launch posture with his legs up and over some handrails. A scientific interest in weightlessness led him to a career in the space life sciences, and a lifelong fascination with spaceflight in general has kept him in the library stacks and on-line archives researching little known aspects of spaceflight history. Charles earned his bachelor of science in biophysics at The Ohio State University and his doctorate in physiology and biophysics at the University of Kentucky. He has been at the Johnson Space Center since 1983, where he investigated the cardiovascular effects of space flight on Space Shuttle astronauts and on crewmembers of the Russian space station Mir. He was mission scientist for the NASA research on American astronauts on Mir, on John Glenn's Space Shuttle flight, and on STS-107, Columbia's last mission in January 2003. In between two stints as Chief Scientist of NASA's Human Research Program, he was Chief of HRP's International Science Office and led the planning for the joint US-Russian year-long ISS mission and its Twins Study. He is a fellow of the Aerospace Medical Association and a full member of the International Academy of Astronautics, has published over 60 scientific articles, and has received several professional awards.John retired from NASA in February 2018, but will continue advocating for human space exploration while doing research in the history of space life sciences.
Brinda Rana PhD is participating in the analysis of data from the NASA Twins Study that focused on identical twins Scott and Mark Kelly. Scott recently become the first US astronaut to spend a year in space while Mark, also an astronaut, remained on earth. The study is beginning to shed light on the physical effects of extremely stressful space travel which seem to correlate to the aging process and the onset of certain diseases. In addition to learning about how the human body might respond to a long trip to Mars, scientists are also learning about how to identify molecular markers for better treatment and prevention of diseases on earth. #NASAtwins NASA Twins Study Stein Institute for Research on Aging UCSD
Mark and Scott Kelly are the only twins that have ever traveled to space — and their experience will be invaluable if we want to get to Mars one day. The brothers are taking part in what NASA calls the Twins Study — a genetic experiment to see how our bodies change in zero gravity in the long term. That’s important to understand before we put humans on a spaceship and send them on a round trip to the Red Planet. Between 2015 and 2016, Scott spent 340 days on the International Space Station, while his genetically identical twin Mark stayed on Earth to function as a control subject. Before, during, and after Scott’s trip, the brothers have been giving NASA numerous biological samples — blood, saliva, poop, you name it. By comparing Scott’s samples with Mark’s, NASA is trying to understand what long-term space travel does to our bodies. Some preliminary findings have already come out. One study showed that Scott’s DNA changed while he was in space: his telomeres — the protective caps on the end of DNA strands — were unexpectedly longer than Mark’s. (Telomere length can affect aging and age-associated diseases.) Another study showed that there were major fluctuations in Scott’s gut bacteria while he lived in zero G compared to his twin. But we’re still waiting for the bulk of the results, and we might not see those for another year or two. While we wait, The Verge spoke on the phone with Mark and Scott to talk about the Twins Study, whether they’d fly to Mars or the Moon next, and what it feels like to be guinea pigs for the sake of space. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Dawn Kernagis is a Research Scientist in the area of human performance optimization and risk mitigation for operators in extreme environments, such as those working in undersea diving, high altitude aviation, and space. Dr. Kernagis came to IHMC from Duke University Medical Center, where her postdoctoral research was funded by the Office of Naval Research and the American Heart Association to identify pathophysiological mechanisms and potential therapeutic targets in multiple forms of acute brain injury. Here’s the outline of this interview with Dr. Dawn Kernagis [00:00:20] STEM-Talk podcast. [00:01:35] Ken Ford. [00:03:44] Keto Summit. [00:04:06] Outside Magazine: Is the High-Fat, Low-Carb Ketogenic Diet Right for You? [00:04:22] NEEMO expedition. [00:08:30] The Twins Study was the first study of its kind to compare molecular profiles of identical twin astronauts with one in space and another on Earth. [00:12:04] Apolipoprotein E (APOE). [00:12:13] STEM-Talk Episode 12: Dale Bredesen Discusses The Metabolic Factors Underlying Alzheimer’s Disease. [00:16:28] Apolipoprotein E4 protective against malaria? [00:19:14] AHS 16 - Steven Gundry - Dietary Management of the Apo E4. [00:20:37] STEM-Talk Episode 14: Dominic D'Agostino. [00:21:28] Lauren Petersen: The Athlete Microbiome Project: The Search for the Golden Microbiome. [00:22:55] A combination of 16S, metagenomic shotgun, and metatranscriptomic sequencing. [00:29:48] Estrogen receptor (ER), progesterone receptor (PR), and HER2 expression. [00:31:16] Python, scikit-learn, TensorFlow. [00:31:32] The R Project for Statistical Computing. [00:33:15] MATLAB. [00:34:10] STEM-TALK Episode 1: Peter Attia On How To Live Longer And Better. [00:35:23] Swiss cheese model, Gareth Lock. [00:40:48] Duke University. [00:41:04] Richard Moon. [00:42:59] NEEMO blog.