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SHOW NOTESWhat impact does surgery have on the body?Intentional trauma Physiological response Psychosocial impact StressWhen we think about surgery, it's essential to understand that it triggers a significant reaction in the body known as the 'stress response.' This response is a complex interplay of hormonal and metabolic changes directly linked to the degree of tissue damage during surgery. It can intensify if there are any complications after the operation. Let's break it down: The whole process starts when the hypothalamic-pituitary-adrenal axis, or HPA axis, kicks into gear. This leads to a surge in hormones like cortisol, growth hormone, glucagon and catecholamines. These hormones are important because they help the body cope with stress by boosting energy availability and adjusting other bodily functions.Ebb phase (0-48hrs)Increased catabolism of stored glycogen (glycogenolysis)Suppression of insulin secretion → transient hyperglycemiaIncreased catecholamines, cortisol, and inflammatory cytokines (IL-6, TNF-α)Flow phase (3-10 days)Hypermetabolism (increased BMR)Increased protein catabolism → muscle breakdown (to provide amino acids for tissue repair and immune function)Increased lipolysis (fat breakdown) for energySustained insulin resistance → continued hyperglycemiaEnhanced GNG Pro-inflammatory response → increased cytokines and acute-phase protein productionIn the initial stages after surgery, the body releases a wave of pro-inflammatory cytokines. These cytokines jumpstart the healing process by promoting inflammation, which is important for healing surgical wounds. However, to keep this inflammation from going overboard, the body soon follows up with anti-inflammatory cytokines.These inflammatory processes have widespread effects across the body. For example, they can influence how the hypothalamus regulates body temperature or how the liver produces certain proteins that help fight infection and aid in wound healing.But here's where it gets even more interesting: other hormones like glucagon, cortisol, and adrenaline also play a role in modulating these responses. They can affect everything from your blood sugar levels to how your cardiovascular system handles the stress.So, why is all this important? Well, by understanding and managing these responses effectively, we can significantly improve how patients recover from surgery. It's all about helping the body maintain balance during a time when it's incredibly vulnerableDisruption of Metabolic Homeostasis: Surgery often disrupts the body's normal metabolic balance, notably through insulin resistance, where cells fail to respond effectively to insulin, leading to 'diabetes of the injury.' Insulin Resistance and Hyperglycemia: Insulin resistance can cause high blood sugar levels, significantly increasing the risk of surgical complications and mortality. Post-surgery, the body may enter a catabolic state, breaking down muscle instead of fat, which impairs wound healing, weakens the immune system, and reduces muscle strength. Increased Risks for Vulnerable Groups: Elderly, diabetics, and cancer patients are particularly at risk due to their compromised metabolic and inflammatory states. These groups have less physiological reserve, leading to pronounced catabolic states and increased risk of severe post-operative complications. Impact on Recovery and Outcomes: The metabolic chaos from insulin resistance to protein loss not only delays recovery but also exacerbates risks of infection and other complications. Effective management of these changes is crucial for improving surgical outcomes and ensuring that patients thrive post-surgery.ERAS helps to mitigate these by Surgery isn't just about the physical repair or removal of tissue; it triggers a cascade of stress responses in the body that can complicate recovery. These include everything from the psychological impacts of anxiety and the physiological effects of fasting to direct tissue damage and the systemic reactions to it, such as fluid shifts and hormonal imbalances.Key Components of ERAS:Comprehensive Care: ERAS isn't just a single technique but a suite of practices designed to address every aspect of the patient's journey — before, during, and after surgery. This approach aims to minimise the stress responses by controlling pain, reducing fasting times, optimising fluid management, and promoting early mobility.Minimising Fasting: One traditional practice that ERAS revises significantly is the preoperative fasting rule. Old guidelines that required fasting from midnight before surgery are now replaced with more lenient, evidence-based practices that allow intake of clear fluids up to two hours and solids up to six hours before surgery. This change helps maintain normal blood glucose levels, reduces stress, and decreases the body's shift into a catabolic (muscle-degrading) state.Nutritional Optimisation: ERAS protocols emphasise the importance of not entering surgery in a depleted state. By allowing a carbohydrate-rich drink shortly before surgery, patients are better hydrated and less anxious, which in turn reduces insulin resistance and preserves muscle mass — critical factors in speeding up recovery post-surgery. Post-operatively, oral nutrition may be delayed by the medical team until bowel function returns, typically taking close to a week. This delay is stated to reduce postoperative complications such as abdominal distension and nausea/vomiting.For the first several days post surgery fluids of limited nutritional value such as water are provided to patient until tolerance is established leading to insufficient nutrition intake during this time increasing the risk of malnutrition. The ERAS protocol promotes early oral intake within 24 hours post surgery departing from traditional fasting practices. Research suggests that between 40-50% of surgical patients have some degree of malnutrition. Pre-operative malnutrition is an independent predictor of poor post-operative outcomes. Therefore addressing malnutrition is a key component of the ERAS protocol.Immune-Enhancing Diets: Post-surgery nutrition is just as crucial. ERAS encourages diets rich in nutrients that bolster the immune system and enhance wound healing. This includes omega-3 fatty acids, which help modulate the inflammatory response; arginine, which supports protein synthesis and tissue growth; glutamine, which is vital for cellular health and recovery; and nucleotides, which are essential for rapid cell division and immune function .Immuno-nutrition is a specialised medical nutrition therapy that has been shown to adjust the body's inflammatory response: It incorporates specific nutrients like omega-3 fatty acids, arginine, polyunsaturated fatty acids, and nucleotides. It's typically recommended starting 5-7 days before surgery and continuing post-operatively for over 7 days or until oral intake meets at least 60% of the patient's nutritional requirements.How can we use this info to optimize surgical outcomes?Patient education Early nutrition pre and post surgery - Minimise fasting time What is ERAS? How does it differ from traditional care/practice?Introduced by Henrik Kehlet in 1997, the Enhanced Recovery After Surgery (ERAS) protocol has revolutionised surgical practices by optimising perioperative care. A key aspect of ERAS is its interdisciplinary approach, involving healthcare professionals from various specialties to minimise surgical stress and facilitate recovery. What is malnutrition?Malnutrition, is defined as an involuntary reduction in body weight, muscle mass and physical capabilities, affects up to 65% of surgical patients and can worsen during hospital stays. Enhancing nutritional status and promoting functional nutrition therapy is essential, even forpatients without evident malnutrition, particularly when prolonged perioperative oral intake challenges arise. Addressing malnutrition is essential for preventing surgical complications, prolongedhospital stays and higher healthcare costs. What are the benefits of ERAS for the patient?It has been shown that the key physiological benefits include:-enhances the body's anabolic processes-promotes wound healing, which is critical for patient recovery.-Reduces the risk of nutritional depletion-Minimises insulin resistance, a common issue post-surgery, allowing for better blood sugar control and improved metabolic function.-Reduce protein catabolism-And lowers the risk of pressure injuries, which can develop due to extended immobility after surgery.What are the benefits of ERAS from a healthcare perspective? From a healthcare perspective, ERAS has been shown to-shorter length of hospital stay for patients,-Lower risk of ICU transfer rates-reduce readmission rates-And all of these improvements lead to lower healthcare costs, not just for the hospital but for the overall healthcare system, as fewer complications and shorter stays reduce the financial strain.Step 1: Screen & StrengthenIf you've lost any weight unintentionally in the lead up to surgery, or been eating poorly because of a reduced appetite, you may be at risk of malnutrition and it's really important to address this prior to surgery. Research suggests that between 40-50% of surgical patients have some degree of malnutrition. Pre-operative malnutrition is an independent predictor of poor post-operative outcomes. Addressing malnutrition is a key component of the ERAS protocol and why it's effective in improving surgical outcomes for patients.Book an appointment with a dietitian who can guide you on appropriate dietary changes to minimise muscle loss, build you up and optimise nutritional status and stores pre-op. A well-nourished body tolerates surgery better, heals faster, has a stronger immune system to fight infection, and experiences fewer complications.Step 2: Consider Immunonutrition If you're planned for major surgery, especially certain cancer and abdominal surgeries, consider the use of an immunonutrition supplement in the 5-7 days pre op. These are the supplements loaded with arginine, n3s, glutamine and nucleotides to support the immune system and reduce inflammatory responses, potentially leading to fewer infections and better recovery.Step 3: Build Your Strength & Energy Stores prior to surgery Carb load with food in the days leading up to surgery - think that big bowl of pasta a footy player would have the night before the grand final. ERAS protocols have significantly reduced or eliminated long periods of "nil by mouth" (NBM) before surgery.Ask your surgical team exactly when you need to stop eating solid food – it might be much later than you think, often around 6 hours before surgery for a light meal. For clear fluids, it could be as little as 2 hours before!We'll make the most of every second to prevent unnecessary dehydration, hunger, anxiety, and preserve your body's energyStep 4: The Pre-Surgery Carb Load using clear fluidsMany ERAS protocols include a special carbohydrate-rich drink taken a few hours before surgery. Your hospital may provide this, but if they don't, we can organise orders for you or point you in the right direction. It's usually a clear, sweet drink. Think of it as topping off your fuel tank right before the 'race'."These have been shown to reduce post-operative insulin resistance (which can slow healing), help maintain muscle strength, can reduce nausea, and improve overall wellbeing. It basically tells your body it's in a 'fed' state, not a 'starvation' state, heading into surgery.This is best done with tailor made medical nutrition drinks as they come prepped with the correct doses of maltodextrin-polymer carbs and a lower osmolality than other solutions, which essentially means they gentler on your gut and better for gastric emptying so they don't linger in your gut during surgery. Always follow surgical instructions, but ideally we're aiming for 100 grams of carbohydrate the night before surgery and about 50 grams of carbohydrate in clear fluids approximately 2 hours before anesthesia. This might look like 4 x 200ml drinks the night before, and 2 the morning of surgery If you can't access these drinks, apple or cranberry juice are reasonable replacements. Drop us an email or message or give us a call if you'd like advice on where to get pre-op and immunonutrition supplement drinks. Then we move on to post op and Step 5 which is aiming to eat early. ERAS encourages starting to eat and drink as soon as it's safe after surgery – often within hours, not days!As soon as your team says it's okay, try sipping water, then progress to other clear fluids, and then light foods as tolerated. Even small, frequent amounts help. This helps to stimulates your gut to start working again, reducing the risk of ileus – a slow, sleepy bowel, provides energy for healing, and can help you feel more normal, faster.If you haven't been told you can eat or drink, keep asking the question! You are your best advocate! Another tip that can help here is step 6: Chew GumIf your team allows it, start chewing sugar-free gum several times a day once you're able. It sounds simple, but it can be surprisingly helpful in mimicking eating even when you're not allowed to, and can stimulate your digestive system to return to usual function sooner and reduce the risk of ileus.Step 7 is to Nourish to Heal This is where we bring in our good friend protein to optimise tissue repair and recovery Include protein rich food at each meal, and chat to us if you're finding this difficult because there are plenty of hacks if you're not feeling up to chicken breast and steak! And finally step 8 is to Listen to Your BodyWhile ERAS encourages early eating, we always want you to be tuned in to your body's cues and speaking up to your medical team and us if something doesn't feel right. There are plenty of interventions that can be used to keep you comfortable while still optimising your nutrition to get the best outcomes from surgery. Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Hübner, M., Klek, S., et al. (2021). ESPEN practical guideline: Clinical nutrition in surgery. Clinical Nutrition, 40(7), 4745-4761.Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Laviano, A., Ljungqvist, O., et al. (2017). ESPEN guideline: Clinical nutrition in surgery. Clinical Nutrition, 36(3), 623-650.Gustafsson, U. O., Scott, M. J., Schwenk, W., Demartines, N., Roulin, D., Francis, N., et al. (2019). Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: 2018. Clinical Nutrition, 38(2), 576-586. (Note: The ERAS® Society website, erassociety.org, is the primary source for the most current and comprehensive suite of procedure-specific guidelines.)Ljungqvist, O., Scott, M., & Fearon, K. C. (2017). Enhanced Recovery After Surgery: A review. JAMA Surgery, 152(3), 292-298.Thiele, R. H., Raghunathan, K., Brudney, C. S., Campos, S., Candiotti, K., Chaves, S., et al. (2016). American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on perioperative fluid management in adults. Perioperative Medicine, 5, 26. (Note: This is an example of ASER/POQI consensus; look for other relevant POQI statements on specific surgical procedures and their nutritional components.)Soon, K., Levy, G. M., Cusack, L. A., Varma, S., & Nicholson, G. A. (2020). The effect of preoperative carbohydrate loading on patient outcomes in elective surgery: A systematic review and meta-analysis. Systematic Reviews, 9(1), 254.Lewis, S. J., Egger, M., Sylvester, P. A., & Thomas, S. (2001). Early enteral feeding versus "nil by mouth" after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. BMJ, 323(7316), 773-776.Osland, E. J., Hossain, M. A., Khan, S., & Memon, M. A. (2014). Effect of timing of oral feeding on patient outcomes after elective colorectal surgery: A systematic review and meta-analysis. Journal of Gastrointestinal Surgery, 18(5), 1039-1051.Braga, M., Gianotti, L., Nespoli, L., Radaelli, G., & Di Carlo, V. (2002). Nutritional approach in malnourished surgical patients: a prospective randomized study. Archives of Surgery, 137(2), 174-180.Marimuthu, K., Varadhan, K. K., Ljungqvist, O., & Lobo, D. N. (2012). A meta-analysis of the effect of combinations of enhanced recovery after surgery (ERAS) interventions on postoperative outcomes. Annals of Surgery, 255(4), 640-649.
In today's episode, we spoke with Shubham Pant, MD, MBBS, and Professor Timothy Elliott, about ongoing research with cancer vaccines. Dr Pant is a professor in the Department of Gastrointestinal Medical Oncology in the Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center in Houston. Dr Elliott is the Kidani Professor of Immuno-oncology in the Nuffield Department of Medicine at the University of Oxford in the United Kingdom. In our exclusive interview, Pant and Elliott discussed the current landscape of vaccines for cancer treatment, ongoing research seeking to extend the benefits of vaccines as cancer management and prevention strategies, and what the future may hold.
Notes et référencesArticle : Preston JF, Mustikka MP, Priestnall SL, Dunkel B, Fischer M-C. Clinical features and outcomes of horses presenting with presumed equine immune mediated keratitis to two veterinary hospitals in the United Kingdom and Finland: 94 cases (2009–2021). Equine Vet J. 2025; 57(3): 598–610. https://doi.org/10.1111/evj.14213Retrouvez toute la synthèse sur la fiche podcast juste ici : https://audmns.com/YfCrKvOPour nous suivre :1. Abonnez-vous à notre chaine pour profiter de l'intégralité des épisodes : Le Quart d'Heure Véto : décrypte et résume en moins de 15 min un article de biblio véto - Sur abonnement uniquementLe Véto du Mois : Partagez le temps d'une interview l'expérience de vétérinaires emblématiques de notre milieu, des rencontres conviviales, comme si nous étions dans votre salon au coin du feu. Podcasts bonus au fil des inspirations... 2. Le ScopeNous partageons avec vous nos dernières découvertes, inspirations, pistes de réflexion, nouveautés… À découvrir et utiliser dès maintenant, TOUT DE SUITE, dans votre quotidien de vétérinaire, de manager, de vie personnelle, de chef d'entreprise… Et tout cela en moins de 5 minutes top chrono un à 2 mardis par mois ! Je souhaite recevoir mon Scope : https://vetmasterclass.com/lescope/ 3. Contactez-nous, suivez-nous et donnez nous votre avis ! Des sujets que vous souhaiteriez approfondir, des références à partager, ou nous faire part de vos feed-backs :Abonnez-vous à notre chaine, donnez nous des étoiles, un commentaire et partagez autour de vous !Sur notre site : https://vetmasterclass.com/Sur Facebook : https://www.facebook.com/VmHorseSur Instagram : https://www.instagram.com/vetmasterclass/Sur YouTube : https://www.youtube.com/channel/UC18ovcWk9e-mFiTL34OQ03gSur Linkedin : https://www.linkedin.com/company/vetmasterclass-horse/about/Belle journée à tous, Et continuez à vivre votre métier avec Passion ! Distribué par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
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YOU HAVE TO LISTEN TO THIS FEATURE with Mr. H from Liquid Assets. They are the makers of an amazing product called IMMUNO 150. This isn't us selling you. This is us informing you and putting our reputation behind a product that has made us feel so much better!No more colds! Quick recovery. You wake up and whatever pain you might have had - it's gone! Or you're much better! OVERNIGHT! Also, there are stories that you might think a miracle was involved but no - unhealthy people have fully recovered from various diseases including cancers - just from taking IMMUNO 150. Click hear to visit their site. IMMUNO150.COM
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VITAMINS HAVE NO PURPOSE WITHOUT MINERALS. IMMUNO 150 ...Everything Your Body NeedsOver 150 Natural IngredientsIMMUNO 150 was formulated to strengthen immune systems and correct many abnormalities and has a track record of being the first over the finish line in that area. Its 70 plant-derived colloidal minerals are the key to its success. This full spectrum of hydrophilic minerals has been blended and synchronized with 80 superb nutrients to produce one of the finest nutritional supplements in the world. Prove it to yourself by comparing the supplement facts and number of minerals in IMMUNO 150 to any other nutritional product.WWW.IMMUNO150.COM
24 Feb 2025 - Immuno-oncology's Expanding Role in Cancer Treatment
YOU HAVE TO LISTEN TO THIS FEATURE with Mr. H from Liquid Assets. They are the makers of an amazing product called IMMUNO 150. This isn't us selling you. This is us informing you and putting our reputation behind a product that has made us feel so much better!No more colds! Quick recovery. You wake up and whatever pain you might have had - it's gone! Or you're much better! OVERNIGHT! Also, there are stories that you might think a miracle was involved but no - unhealthy people have fully recovered from various diseases including cancers - just from taking IMMUNO 150. Click hear to visit their site. IMMUNO150.COM
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YOU HAVE TO LISTEN TO THIS FEATURE with Mr. H from Liquid Assets. They are the makers of an amazing product called IMMUNO 150. This isn't us selling you. This is us informing you and putting our reputation behind a product that has made us feel so much better!No more colds! Quick recovery. You wake up and whatever pain you might have had - it's gone! Or you're much better! OVERNIGHT! Also, there are stories that you might think a miracle was involved but no - unhealthy people have fully recovered from various diseases including cancers - just from taking IMMUNO 150. Click hear to visit their site. IMMUNO150.COM
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YOU HAVER TO LISTEN TO THIS FEATURE with Mr. H from Liquid Assets. They are the makers of an amazing product called IMMUNO 150. This isn't us selling you. This is us informing you and putting our reputation behind a product that has made us feel so much better!No more colds or quick recovery. You wake up and whatever pain you might have had - it's gone! Or it's much better! OVERNIGHT! Also, there are stories that you might think a miracle was involved but no - unhealthy people have fully recovered from various diseases including cancers - just from taking IMMUNO 150. Click hear to visit their site. IMMUNO150.COM
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Exceptional Health Products is a division of Liquid Assets, Inc. that was incorporated in the state of Oklahoma in 1983. The principals are Mr. Elmer Heinrich and his wife Shirley. Mr. Heinrich, (more commonly known as Mr. H) is the company President and CEO. Liquid Assets opened it first plant minerals mine in Utah in 1984 and since then, has sold it's SenTraMin minerals in 27 countries. These minerals are the base of the company's fabulous nutritional product called Immuno 150. Mr. H has owned and operated successful companies in seven countries. The Heinrich foundation is basically the parent of all entities beginning with S and H Drilling, The Hotsy Corporation, Robo Car Wash Company, Rockett Water filters, The Rockland Corporation, The Rockland Mineral mine, Hospital Santa Monica in Mexico, and now Exceptional Health Products.The company has been blessed to have been able work with its chemist's and many mineral users, over an extended period, to formulate a combination of various nutritional constituents with its 70 plant minerals that are scientifically comingled, in Immuno 150, to be compatible with the human digestive system for total assimilation. Based on 40 years of experience in the plant minerals business, serving millions of people, the principles of Exceptional Health Products are convinced The World is Sick due to a lack of minerals in food.888.316.2224www.immuno150.com
Exceptional Health Products is a division of Liquid Assets, Inc. that was incorporated in the state of Oklahoma in 1983. The principals are Mr. Elmer Heinrich and his wife Shirley. Mr. Heinrich, (more commonly known as Mr. H) is the company President and CEO. Liquid Assets opened it first plant minerals mine in Utah in 1984 and since then, has sold it's SenTraMin minerals in 27 countries. These minerals are the base of the company's fabulous nutritional product called Immuno 150. Mr. H has owned and operated successful companies in seven countries. The Heinrich foundation is basically the parent of all entities beginning with S and H Drilling, The Hotsy Corporation, Robo Car Wash Company, Rockett Water filters, The Rockland Corporation, The Rockland Mineral mine, Hospital Santa Monica in Mexico, and now Exceptional Health Products.The company has been blessed to have been able work with its chemist's and many mineral users, over an extended period, to formulate a combination of various nutritional constituents with its 70 plant minerals that are scientifically comingled, in Immuno 150, to be compatible with the human digestive system for total assimilation. Based on 40 years of experience in the plant minerals business, serving millions of people, the principles of Exceptional Health Products are convinced The World is Sick due to a lack of minerals in food.888.316.2224www.immuno150.com
2nd July, 2024– Join Patricia Keane every Tuesday on Radio Maria Ireland to learn more about how to improve your health! In this episode, Patricia continues her discussion on the disrupted immuno metabolism, the hidden culprits behind complex health issues, and why our immune system doesn't work the way it should work. The post E260 | Health and Faith Matters – Patricia Keane – Beyond the Surface: Investigating Disrupted Immuno-Metabolism appeared first on Radio Maria Ireland.
25th June, 2024– Join Patricia Keane every Tuesday on Radio Maria Ireland to learn more about how to improve your health! In this episode, Patricia delves into the fascinating and intricate world of disrupted immuno metabolism, shedding light on how this often-overlooked factor plays a crucial role in a wide range of complex health issues. The post E259 | Health and Faith Matters – Patricia Keane – Immuno Metabolism Unveiled: The Link to Hidden Health Challenges appeared first on Radio Maria Ireland.
I had the pleasure of speaking with Dr. Jeffrey Bland, MD, the Founding Father of Functional Medicine. Listen in as we discuss how he came to start the functional medicine movement and became a leader in personalized medicine. We also explore the dynamic nature of our immune systems and discuss revolutionary ways to rejuvenate it, a process Dr. Bland refers to as “immuno-rejuvenation.” Plus, you won't want to miss the fascinating story of how Dr. Bland rediscovered Himalayan Tartary Buckwheat, an ancient, immune-boosting superfood, now being reintroduced through his company, Big Bold Health. Dr. Jeffrey Bland is a personable and highly respected thought leader who has spent more than five decades focused on the improvement of human health. He is known worldwide as the founder of the Functional Medicine movement. His pioneering work has created the Personalized Lifestyle Medicine Institute, as well as the Institute for Functional Medicine, the global leader in Functional Medicine education. Dr. Bland's latest project is Big Bold Health, where he's on a mission to transform the way people think about one of nature's greatest innovations—the immune system. 00:50 Introducing Dr. Jeff Bland: The Pioneer of Functional Medicine 02:35 The Genesis of Functional Medicine: Dr. Bland's Journey 09:26 The Evolution and Impact of Functional Medicine 23:41 Immuno-rejuvenation: A New Frontier in Health and Longevity 30:57 The Immune-Boosting Superfood: Himalayan Tartary Buckwheat 41:44 Understanding Immunologic Age and Its Measurement 45:25 The Future of Personalized Medicine and Lifestyle Changes 50:30 Big Bold Health: A Venture into Immuno-rejuvenation 53:40 Agricultural Innovations and Sustainable Practices at Big Bold Health 01:09:12 The 3 things you can do to Take Back Your Health and how to connect with Big Bold Health Connect with Amy Myers, MD Website: https://www.amymyersmd.com/ Instagram: https://www.instagram.com/dramymyers YouTube: https://www.youtube.com/@AmyMyersMD/featured Newsletter: https://www.amymyersmd.com/ec/guide-to-leaky-gut Facebook: https://www.facebook.com/AmyMyersMD Twitter: https://twitter.com/AmyMyersMD Pinterest: https://www.pinterest.com/amymyersmd/ Connect with Dr. Jeffrey Bland PhD Website: https://bigboldhealth.com/ Facebook: https://www.facebook.com/bigboldhealth/ Instagram: https://www.instagram.com/bigboldhealth/
This week we have a follow-up with Boone Zavik from Immuno Labs to go through and discuss our results from the food testing! https://www.getoutinit.events/ - Our website; come check us out and sign up for our newsletter! You'll get bunches of fun freebies and up-to-the-minute info on our Get Out In It sports camps. Find us on: YouTube: https://www.youtube.com/channel/UCO2NpPBc-irzTwu48_1ZSqA Facebook: https://www.facebook.com/profile.php?id=100091353277028 Instagram: https://www.instagram.com/getout_in_it/ Twitter: https://twitter.com/GetOutInIt Pinterest: https://www.pinterest.co.uk/GetOutInIt/ Spotify Playlist: https://open.spotify.com/playlist/5X1B1T5K35CzwuMql7i06j?si=87bc3af7f7034f50 Immuno Labs: https://www.immunolabs.com/
Exceptional Health Products is a division of Liquid Assets, Inc. that was incorporated in the state of Oklahoma in 1983. The principals are Mr. Elmer Heinrich and his wife Shirley. Mr. Heinrich, (more commonly known as Mr. H) is the company President and CEO. Liquid Assets opened it first plant minerals mine in Utah in 1984 and since then, has sold it's SenTraMin minerals in 27 countries. These minerals are the base of the company's fabulous nutritional product called Immuno 150. Mr. H has owned and operated successful companies in seven countries. The Heinrich foundation is basically the parent of all entities beginning with S and H Drilling, The Hotsy Corporation, Robo Car Wash Company, Rockett Water filters, The Rockland Corporation, The Rockland Mineral mine, Hospital Santa Monica in Mexico, and now Exceptional Health Products.The company has been blessed to have been able work with its chemist's and many mineral users, over an extended period, to formulate a combination of various nutritional constituents with its 70 plant minerals that are scientifically comingled, in Immuno 150, to be compatible with the human digestive system for total assimilation. Based on 40 years of experience in the plant minerals business, serving millions of people, the principles of Exceptional Health Products are convinced The World is Sick due to a lack of minerals in food.visit their website here - IMMUNO 150 to order!
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Send us a Text Message.Episode 131 of the Long Covid Podcast is a chat with the wonderful Dr Wes Ely, internist & pulmonologist, clinical triallist & also author & Long Covid advocate. We chat through some of his experiences with Long Covid patients as well as the clinical trial of baricitinib for Long Covid which is enrolling very soon.ICUdelirium.org Stat News - "Don't give longhaulers the silent treatment"RVLC - Reverse Long Covid trial on Clinicaltrials.gov RVLC Trial websiteEvery Deep Drawn Breath bookCOV-BARRIER study For more information about Long Covid Breathing, their courses, workshops & other shorter sessions, please check out this link(music - Brock Hewitt, Rule of Life) Support the Show.~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~The Long Covid Podcast is self-produced & self funded. If you enjoy what you hear and are able to, please Buy me a coffee or purchase a mug to help cover costs.Transcripts are available on the individual episodes hereShare the podcast, website & blog: www.LongCovidPodcast.comFacebook @LongCovidPodcastInstagram & Twitter @LongCovidPodFacebook Support GroupSubscribe to mailing listPlease get in touch with feedback and suggestions or just how you're doing - I'd love to hear from you! You can get in touch via the social media links or at LongCovidPodcast@gmail.com**Disclaimer - you should not rely on any medical information contained in this Podcast and related materials in making medical, health-related or other decisions. Ple...
Exceptional Health Products is a division of Liquid Assets, Inc. that was incorporated in the state of Oklahoma in 1983. The principals are Mr. Elmer Heinrich and his wife Shirley. Mr. Heinrich, (more commonly known as Mr. H) is the company President and CEO. Liquid Assets opened it first plant minerals mine in Utah in 1984 and since then, has sold it's SenTraMin minerals in 27 countries. These minerals are the base of the company's fabulous nutritional product called Immuno 150. Mr. H has owned and operated successful companies in seven countries. The Heinrich foundation is basically the parent of all entities beginning with S and H Drilling, The Hotsy Corporation, Robo Car Wash Company, Rockett Water filters, The Rockland Corporation, The Rockland Mineral mine, Hospital Santa Monica in Mexico, and now Exceptional Health Products.The company has been blessed to have been able work with its chemist's and many mineral users, over an extended period, to formulate a combination of various nutritional constituents with its 70 plant minerals that are scientifically comingled, in Immuno 150, to be compatible with the human digestive system for total assimilation. Based on 40 years of experience in the plant minerals business, serving millions of people, the principles of Exceptional Health Products are convinced The World is Sick due to a lack of minerals in food.visit their website here - IMMUNO 150 to order!
Today on Conscious Talk we'll be talking about mastering our Immuno-Metabolism and adopting a new focus for vitality and resilience in a challenging world with Kat James. Website: www.EssentialFormaulas.com | www.InformedBeauty.com Learn more about your ad choices. Visit podcastchoices.com/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today on Conscious Talk we'll be talking about mastering our Immuno-Metabolism and adopting a new focus for vitality and resilience in a challenging world with Kat James. Website: www.EssentialFormaulas.com | www.InformedBeauty.com
Four-plus years after the first outbreak, people who've been vaccinated or who had Covid are still being infected. Where are we now?
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Immuno-dermatology, stuck in a “cassette world” of steroid treatments, needs to move to the digital era, according to Dermavent CEO Todd Zavodnick, whose drug Vtama is the first FDA-approved non-steroidal cream for plaque psoriasis. Lecia Bushak provides an update on yet another PBM reform bill introduced in Congress, and how the PBM industry is responding. Meanwhile, Elon Musk's update on Neuralink's first human patient tops our Trends segment, along with Brian Wilson's conservatorship amid a dementia diagnosis and Joe Rogan's podcast sparks an AIDS denialism controversy. Music by Sixième Son. Check us out at: mmm-online.com Follow us: YouTube: @MMM-onlineTikTok: @MMMnewsInstagram: @MMMnewsonlineTwitter/X: @MMMnewsLinkedIn: MM+M To read more of the most timely, balanced and original reporting in medical marketing, subscribe here.
BUFFALO, NY- February 19, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland.” Selective tropomyosin receptor kinase (TRK) inhibitors are approved targeted therapies for patients with solid tumors harboring a neurotrophic tyrosine receptor kinase (NTRK) gene fusion. Country-specific estimates of NTRK gene fusion frequency, and knowledge on the characteristics of affected patients, are limited. In this new study, researchers Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand, and Jihong Zong from Bayer HealthCare Pharmaceuticals Inc., University of Turku, Turku University Hospital, Technical University Dresden, and Western Finland Cancer Centre identified patients with histologically-confirmed papillary thyroid cancer (PTC) from Finland's Auria Biobank. “The study objectives were to determine the frequency of NTRK gene fusion in patients with PTC in Finland, and to describe co-occurring genetic alternations, clinical characteristics, disease progression, and treatment pathways in NTRK gene fusion positive patients.” TRK protein expression was determined by pan-TRK immunohistochemistry. Immuno-stained tumor samples were scored by a certified pathologist. Gene fusions and other co-occurring gene alterations were identified by next generation sequencing. Patient characteristics and vital status were determined from linked hospital electronic health records (EHRs). Patients were followed from 1 year before PTC diagnosis until death. 6/389 (1.5%) PTC patients had an NTRK gene fusion (all NTRK3); mean age 43.8 years (and none had comorbidities) at PTC diagnosis. Gene fusion partners were EML4 (n = 3), ETV6 (n = 2), and RBPMS (n = 1). Of 3/6 patients with complete EHRs, all received radioactive iodine ablation only and were alive at end of follow-up (median observation, 9.12 years). “In conclusion, NTRK gene fusion is infrequent in patients with PTC. Linkage of biobank samples to EHRs is feasible in describing the characteristics and outcomes of patients with PTC and potentially other cancer types.” DOI - https://doi.org/10.18632/oncotarget.28555 Correspondence to - Jihong Zong - jihong.zong@bayer.com Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28555 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, NTRK gene fusion, papillary thyroid cancer, clinicogenomic, epidemiology, biobank About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957
Hosts:Pradip Kamat, Children's Healthcare of Atlanta/Emory University School of MedicineRahul Damania, Cleveland Clinic Children's HospitalIntroductionToday, we discuss the case of an 8-month-old infant with severe bronchospasm and abnormal blood gas. We'll delve into the epidemiology, pathophysiology, and evidence-based management of acute bronchiolitis.Case SummaryAn 8-month-old infant presented to the ER with decreased alertness following worsening work of breathing, preceded by URI symptoms. The infant was intubated and transferred to the PICU, testing positive for RSV. Initial blood gas showed 6.8/125/-4, and CXR revealed massive hyperinflation. Vitals: HR 180, BP 75/45, SPO2 92% on 100% FIO2, RR 12 (prior to intubation), now around 16 on the ventilator, afebrile.Discussion PointsEtiology & Pathogenesis: Bronchiolitis is primarily caused by RSV, with other viruses and bacteria playing a role. RSV bronchiolitis is the most common cause of hospitalization in infants, particularly in winter months. Immuno-pathology involves an unbalanced immune response and can lead to various extra-pulmonary manifestations.Diagnosis: Diagnosis is clinical, based on history and examination. Key signs include upper respiratory symptoms followed by lower respiratory distress. Blood gas, chest radiography, and viral testing are generally not recommended unless warranted by severe symptoms or clinical deterioration.Management Framework: For patients requiring PICU admission, focus on oxygenation and hydration. High-flow therapy and nasal continuous positive airway pressure (CPAP) can be used. Hydration and feeding support are crucial. Antibiotics, steroids, and bronchodilators are generally not recommended. Mechanical ventilation and ECMO may be necessary in severe cases.Immunoprophylaxis & Nosocomial Infection Prevention: Palivizumab and nirsevimab are used for RSV prevention in high-risk infants. Strict infection control measures, including hand hygiene and isolation, are essential to prevent nosocomial infections.ConclusionRSV bronchiolitis is a common and potentially severe respiratory illness in infants. Management focuses on supportive care, with a careful balance between oxygenation and hydration. Immunoprophylaxis and infection control are crucial in preventing the spread of the virus.Thank you for listening to our episode on acute bronchiolitis. Please subscribe, share your feedback, and visit our website at picudoconcall.org for more resources. Stay tuned for our next episode!ReferencesRogers - Textbook of Pediatric Critical Care Chapter 49: Pneumonia and Bronchiolitis. De Carvalho et al. page 797-823Reference 1: Dalziel, Stuart R; Haskell, Libby; O'Brien, Sharon; Borland, Meredith L; Plint, Amy C; Babl, Franz E; Oakley, Ed. Bronchiolitis. The Lancet. , 2022, Vol.400(10349), p.392-406. DOI: 10.1016/S0140-6736(22)01016-9; PMID:...
So we're at the start of our month of no-processed food -and this week we are lucky enough to be joined by Boone Zavik from Immuno Laboratories. Immuno specialises in the link between what people eat and how they feel. So what better way to kick off this month than a hike and a chat with Boone! https://www.getoutinit.events/ - Our website; come check us out and sign up for our newsletter! You'll get bunches of fun freebies and up-to-the-minute info on our Get Out In It sports camps. Find us on: YouTube: https://www.youtube.com/channel/UCO2NpPBc-irzTwu48_1ZSqA Facebook: https://www.facebook.com/profile.php?id=100091353277028 Instagram: https://www.instagram.com/getout_in_it/ Twitter: https://twitter.com/GetOutInIt Pinterest: https://www.pinterest.co.uk/GetOutInIt/ Spotify Playlist: https://open.spotify.com/playlist/5X1B1T5K35CzwuMql7i06j?si=87bc3af7f7034f50 Weekly Post: Runs With Emily: https://www.instagram.com/reel/C27OTUsN8cP/?igsh=amh4OXJiOGpxb3Ns Immuno Labs: https://www.immunolabs.com/
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In this episode, Dr. Stephanie interviews her close friend and Naturopathic Doctor, Dr. Nick Baboulas. Formerly a Medicinal Chemist leading the charge in pharmaceutical discovery, Dr. Nick's life took an unexpected turn when his sister fell ill. This is when he knew he needed a career change. Deciding between conventional medical school and naturopathic medicine, he embraced the latter, forever changing the trajectory of his career.Grab your headphones or turn the volume up and get ready to unravel the mysteries of Low Dose Immuno or Antigen Therapy, popularly known as LDIs and LDAs. Dr. Stephanie and Dr. Nick, plunge into the depths of this cutting-edge therapy, exploring its applications, methodologies, and the myriad of conditions that stand to gain from its unique approach.They bring their combined expertise to the forefront, offering a comprehensive understanding of this hot topic, including analogies that really make sense and provide a better understanding of how your immune system works. With a wealth of knowledge and personal experiences, they navigate through the complexities of this therapy, providing listeners with a nuanced perspective on its applications.Whether you're a seasoned health enthusiast or just diving into the world of alternative treatments, Dr. Stephanie and Dr. Nick are here to guide you through the fascinating realm of LDIs and LDAs, showcasing the potential of this groundbreaking therapy for various health conditions.More about Dr. Nick: Dr. Baboulas first career was as a “Medicinal Chemist' working in the Pharmaceutical Industry, however, personal family circumstances changed his career path and he went to Naturopathic Medical School to become a Naturopathic Doctor.Dr. Baboulas experiences have shaped his way/philosophy on how to view disease/illness and the patient; therefore, he tries to understand the patient's current pathological state from a Bioregulatory/ Integrative Biological Medicine standpoint. He has done extensive training in many disciplines around North America and Europe with world-renowned Doctors in their respective fields, and very lucky to be able to call some of them his mentors!Dr. Baboulas' style is eclectic, where he utilizes whatever modalities best fit his patient's condition/current state. Clinically, he focuses on supporting patients with complex chronic illness, such as autoimmune disease, Lyme, Mold Illness, CFS, Fibromyalgia, etc. He knows that there is hope, patients can reach their optimal health, and he is thereto support them along that healing journey.To get in touch with Dr. Nick please check out his website here and his Instagram account here. And to contact him directly please email info@eirinihealingsolutions.ca.Follow Dr. Stephanie on Instagram here.Follow Dr. Stephanie's Functional Medicine Clinic - Vagus Clinic here.For more resources and how to work with Vagus Clinic - check out the website here.
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The immune system, with its pivotal role in animal health, exerts a direct influence on growth, reproduction, milk production, and overall performance. This has given rise to immuno-nutrition, where dietary components are harnessed to enhance immune function. This approach is reshaping perspectives within the animal production sector, emphasizing the profound impact of diet on the well-being and productivity of livestock. In this episode, Dr. Melina Bonato delves into the intricate realm of animal nutrition, specifically focusing on ruminants. Dr. Bonato emphasizes the critical role of immuno-nutrition in optimizing ruminant health and production, covering topics such as the influence of nutrition on the immune system and the challenges associated with ruminal acidosis. "The concept of 'immuno-nutrition' involves optimizing an animal's nutrition to support its immune system's response to challenges like infections or stress."What you'll learn:(00:00) Highlight(02:34) Introduction(11:41) Immuno-nutrition applied to ruminant production(15:54) Immuno-nutrition concept(22:07) Use of beta glucan in cattle(26:48) Chronic issues of acidosis in cattle(28:06) Role of components of yeast in supporting rumen microbiota(32:55) The final questionsMeet the guest: Dr. Melina Bonato Experience:Current: Global Technical and R&D Manager in ICC Animal NutritionBackground:Ph.D., Animal Science (São Paulo State University)M.Sc., Animal Science (São Paulo State University)B.Sc., Animal Science (São Paulo State University)Connect with the guest!The Dairy Podcast Show is trusted and supported by innovative companies like:- ICC* Adisseo- Phibro- Protekta- smaXtec- Berg + Schmidt- Diamond V- dsm-firmenich- AB Vista- Evonik
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References Schubert. F. 1826. "Ständchen" D.899 Immunol Rev. 2020 May; 295(1): 101–113. Nat Metab. 2022 Sep;4(9):1202-1213 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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Himalayan Tartary Buckwheat (let's call it “HTB” so as not to get too long in the tooth) is a hardy plant that has been farmed in Asia for generations but is largely unknown in the rest of the world. Modern analyses have revealed that HTB contains significantly higher levels of phytonutrients compared to common buckwheat—up to a 100-fold increase of certain immune-strengthening flavonoids. It also contains other nutrients that help build, maintain, and protect muscles and lean tissues throughout the body, improve how it deals with certain toxins, produce cellular energy, and more. Yes, that's all from one tiny humble buckwheat plant. Thanks to those health benefits, HTB is a go-to ingredient of mine in the kitchen, and I feature it in several recipes in my Boundless Cookbook. The mastermind behind HTB is Dr. Jeffrey Bland, Ph.D., a Clinical Biochemist known as the “Father of Functional Medicine.”An immunity expert, the founder of the Institute for Functional Medicine (IFM), best-selling author, thought leader, and educator, Dr. Bland is also the president of Big Bold Health, the company that produces HTB. Big Bold Health's mission is to engage people worldwide to actively participate in reshaping the conversation about immunity, resilience, and the interconnectedness of plants, people, and the planet. Dr. Bland is advocating for the power of immuno-rejuvenation to enhance immunity at a global level. Full Show Notes: https://bengreenfieldlife.com/drbland Episode sponsors: Levels: If you want to better understand how food affects your health by trying continuous glucose monitor, go to levels.link/Ben to learn more. They also have a really well-researched, in-depth blog that I recommend checking out if you're just looking to learn more about topics like metabolic health, longevity, and nutrition. BON CHARGE: Holistic wellness brand with a wide range of products that naturally address the issues of our modern way of life. They can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Apollo: Apollo is a safe and non-invasive wearable that actively improves your sleep. Head over to apolloneuro.com/bengreenfield and use code BG15 for 15% off Henson Shaving: Go to hensonshaving.com and enter BEN at checkout to get 100 free blades with your purchase. (Note: you must add both the 100-blade pack and the razor for the discount to apply. Bubs Naturals: Ready for a discount on the highest quality MCT oil powder, collagen protein, apple cider vinegar gummies, and more? Use code BENG for 20% off at bubsnaturals.com.
In this episode, we are revisiting a talk about an inside-out approach to how we diagnose disease. Immuno-engineer and TED Fellow Aaron Morris unveils implantable technology that gives real-time, continuous analysis of a patient's health at the molecular level. "We're creating a diagnostic lab inside your body," Morris says -- and it may pave the way to diagnosing and treating disease better and faster than ever before.
I am here with Dr. Jeffrey Bland, who is largely considered the father of functional medicine. He is a clinical biochemist and immunity expert, and founder of the Institute for Functional Medicine and the Personalized Lifestyle Institute, which is PLMI. He is also a bestselling author, thought leader, educator, entrepreneur, speaker and president of Big …
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