Support cells in the nervous system
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In This Episode Financial institutions (FIs) are currently navigating a “perfect storm” of technological, market, and consumer shifts. They face a multi-front war: constant economic and regulatory pressure, soaring consumer expectations for 24/7 personalization, and the existential threat of megabanks with massive tech budgets. To survive and thrive, FIs must move beyond “pilot purgatory”—where 95% of generic AI pilots fail—and adopt a banking-specific AI workforce,an AI-powered intelligence layer for modern banking. In this episode of Breaking Banks host Jason Henrichs is joined by Dan Michaeli, CEO & Co-Founder of Glia, a digital customer service and banking AI platform serving over 700 FIs, and Madeline Fredin, SVP of Growth & AI Transformation at Alloy Labs to explore how a self-learning institutional brain unifies data across the organization. By starting with the contact center—the richest source of unstructured interaction data—banks can build a foundation that shifts their entire operation from reactive service to proactive growth and agentic workflows.
Most SaaS leaders are asking the wrong question. They obsess over NPS and CSAT scores, celebrate high satisfaction ratings, and then watch customers quietly disappear. In this episode, Jeff Mains sits down with Rick DeLisi — co-founder of The Effortless Experience, creator of the Customer Effort Score (CES), and Chief Evangelist at Glia — to challenge one of the most dangerous myths in customer experience: that satisfaction equals loyalty.Rick reveals why the real driver of customer retention isn't how happy customers feel — it's how hard they had to work to get what they needed. He introduces the concept of "insidious disloyalty," explains why product failures are actually service failures in disguise, and lays out how AI can dramatically reduce customer effort when deployed correctly. For SaaS founders focused on retention, this episode is a fundamental shift in how to think about keeping customers.Key Takeaways4:22 — **The wrong question** — Rick explains why CSAT and NPS are company-centric metrics that don't predict future loyalty. The right question: "How much effort was required for you to get what you needed?"6:35 — **Insidious disloyalty** — Customers who leave without saying a word are more dangerous than those who complain. Silent churn gives you no opportunity to recover the relationship or learn from the failure.10:04 — **Customers want to stay** — Customers don't want to switch vendors. The goal isn't to build loyalty — it's to stop destroying it with high-effort experiences.11:23 — **Mitigate disloyalty, don't try to promote loyalty** — Promoting loyalty is less fruitful than eliminating the friction that causes customers to start looking elsewhere.14:37 — **There's no such thing as a product failure** — Every product failure immediately becomes a service issue. Future loyalty is shaped by how the service team responds, not by the failure itself.29:15 — **The biggest misconception about customer service** — Not every interaction is a relationship-building moment. Forcing fake friendliness on transactional interactions feels disrespectful, not warm.31:41 — **Neither extreme works** — Full automation fails just as surely as requiring humans for everything. The winning approach is intelligently routing issues to AI or live agents based on complexity.41:59 — **Surveys are just the entry point** — Quantitative survey scores tell you almost nothing. The real insight comes from qualitative follow-up conversations, and you need far fewer than you think.45:35 — **What customers are actually loyal to** — Customers aren't loyal to your company. They're loyal to their own decision to become your customer. Probe how your product makes them feel about themselves.45:58 — **The reframe** — Stop asking what customers think of you. Start asking how customers feel about themselves as a result of choosing you.Tweetable Quotes"The single question you can ask right after a service interaction to predict future loyalty: How much effort was required for you to get what you needed?" — Rick DeLisi"Insidious disloyalty is the customer who quietly disappears in the night. No explanation. No opportunity to recover. You didn't even learn anything." — Rick DeLisi"Trying to promote loyalty is far less fruitful than mitigating disloyalty." — Rick DeLisi"There's no such thing as a product failure. The moment something breaks, it becomes a service issue — and your customer's future loyalty depends on how you handle it." — Rick DeLisi"Customers aren't loyal to your company. They're loyal to their own decision to become your customer." — Rick DeLisi"Stop asking what customers think of you. Ask how customers feel about themselves as a result of being your customer." — Rick DeLisi"Your success in marketing is getting a customer to think about you 1% more. Your success in service is the moment they forget it was ever a problem." — Rick DeLisi"AI should be a part of every interaction — making things easier for customers, easier for your frontline, and more efficient for your company." — Rick DeLisiSaaS Leadership Lessons1. The metric you're measuring may be the reason you're losing customers. CSAT and NPS are lagging, company-centric indicators. They make you feel good but don't predict churn. Customer Effort Score — how hard someone had to work to get what they needed — is the far more accurate signal. Build your CX measurement strategy around effort, not satisfaction.2. Silent churn is the most expensive kind. Customers who leave without complaining are more costly than angry ones. Vocal detractors give you a chance to save the relationship and learn from it. The quiet exits give you nothing. Map your customer journey specifically to identify where insidious disloyalty can take root — low engagement, repeated friction, unanswered needs — before customers start shopping elsewhere.3. Your job isn't to create loyalty. It's to stop destroying it. Customers who sign up with you are already loyal — they just made the decision to trust you. Your real job is to protect that trust by removing friction at every touchpoint. Every high-effort support interaction is a crack in the foundation of a relationship that took real sales effort to build.4. Every product bug is a customer service test. When something breaks, customers don't remember the bug — they remember how you handled it. A fast, effortless resolution can actually strengthen loyalty. A slow, frustrating one will cost you the relationship even if you technically solved the problem. Invest in your service response capability as seriously as you invest in product quality.5. AI reduces effort — but only when it knows its lane. Generic AI frustrates customers. Vertical, context-aware AI resolves routine issues instantly and hands off complex ones to live agents with full context already loaded. The bar for good AI in service is simple: does it make the customer's experience easier or harder? If a customer has to fight through your automation, you've made the problem worse.6. In B2B SaaS, your champion's ego is part of the product. The person who bought your software has personal equity in that decision. When your product makes them look smart, delivers real ROI, and gives them a competitive edge internally, they become your best retention tool. When it doesn't, they quietly stop defending you. Probe how your product makes your champions feel about themselves — not just how it performs on paper.Guest Resourcesrick.delisi@glia.comwww.glia.comhttps://www.linkedin.com/in/rick-delisi-1122257/Episode SponsorThe Futureproof Series - https://www.youtube.com/playlist?list=PLfkXKUPZ5xuOqMPR7_gzGybncTtavyR1NThe Captain's KeysSmall Fish, Big Pond – https://smallfishbigpond.com/ Use the promo code ‘SaaSFuel'Champion Leadership Group – https://championleadership.com/SaaS Fuel ResourcesWebsite - https://championleadership.com/Jeff Mains on LinkedIn - https://www.linkedin.com/in/jeffkmains/Twitter - https://twitter.com/jeffkmainsFacebook - https://www.facebook.com/thesaasguy/Instagram - https://instagram.com/jeffkmains
In this monolog, Vijay talks about a 2026 article that showed there is epigenetic memory in adult glial cells that allows them to regenerate but also paves the way for their malignant transformation.
It's an Emmajority Report Thursday on The Majority Report On today's program: Donald Trump issues more meaningless threats on Truth Social towards Iran. This time he claims to have ordered the U.S. Navy to sweep the Strait of Hormuz for mines at a tripled-up level (?) and to kill all Iranian boats (?) that are laying those mines. Secretary of Agriculture Brooke Rollins is asked by Stuart Varney what her plan is to address the looming fertilizer crisis caused by the war and she has no answer. Gil Duran, publisher of the Nerd Reich newsletter joins the program to discuss the "Palantir Manifesto". Jodie Ginsberg, CEO of the Committee to Protect Journalists, joins Emma to discuss Israel murdering Lebanese journalist, Amal Khalil. Dr. Tarek Loubani makes an appreciation video for Emma's birthday fundraising effort for the Glia Project which raised enough funds to full operate a wound care facility in Gaza for a month. It's never too late to chip in if you can by visiting Glia.org. In the Fun Half: Reese Witherspoon and Sandra Bullock try to frame their shilling for AI as feminism. Vinny from the PBD Podcast pushes his co-host Adam Sosnick over his what-aboutism tactic in defense of the IDF smashing a statue of Christ. Congressional candidate Jack Schlossberg really fumbles questions about Israel as he cannot bring himself to admit Netanyahu is a war criminal or that the U.S. should stop arming Israel. All that and more. To connect and organize with your local ICE rapid response team visit ICERRT.com The Congress switchboard number is (202) 224-3121. You can use this number to connect with either the U.S. Senate or the House of Representatives. Follow us on TikTok here: https://www.tiktok.com/@majorityreportfm Check us out on Twitch here: https://www.twitch.tv/themajorityreport Find our Rumble stream here: https://rumble.com/user/majorityreport Check out our alt YouTube channel here: https://www.youtube.com/majorityreportlive Gift a Majority Report subscription here: https://fans.fm/majority/gift Subscribe to the AMQuickie newsletter here: https://am-quickie.ghost.io/ Join the Majority Report Discord! https://majoritydiscord.com/ Get all your MR merch at our store: https://shop.majorityreportradio.com/ Get the free Majority Report App!: https://majority.fm/app Go to https://JustCoffee.coop and use coupon code majority to get 10% off your purchase Check out today's sponsors: SHOPIFY: Sign up for a $1/month at shopify.com/majority AURA FRAMES: Exclusive $25-off Carver Mat at AuraFrames.com/MAJORITY. Promo Code MAJORITY TRUST AND WILL: Get 20% off trustandwill.com/MAJORITY SUNSET LAKE CBD: Use coupon code "Left Is Best" for 20% off of your entire order at SunsetLakeCBD.com Follow the Majority Report crew on Twitter: @SamSeder @EmmaVigeland @MattLech On Instagram: @MrBryanVokey Check out Matt's show, Left Reckoning, on YouTube, and subscribe on Patreon! https://www.patreon.com/leftreckoning Check out Matt Binder's YouTube channel: https://www.youtube.com/mattbinder Subscribe to Brandon's show The Discourse on Patreon! https://www.patreon.com/ExpandTheDiscourse Check out Ava Raiza's music here! https://avaraiza.bandcamp.
References Clin Exp Rheumatol . 2019 Sep-Oct;37(5):715-722Front Neurol. 2024 Jul 3;15:1396520. Glia. 2021 Jan 2;69(5):1216–1240Guerra, DJ.2026. Unpublished LecturesMozart, WA. 1786. Symphony 38 in D Major." Prague". K. 504https://music.youtube.com/watch?v=tLinpqckLGw&si=oKPtpiJJDEuoEHjBBalin, M. 1966. Coming Back to Me Jefferson Airplanehttps://open.spotify.com/track/0TBntp6t4oS6UXjxikO5n7?si=20e475b0642c433b
Rick DeLisi, Lead Research Analyst at Glia and co-author of The Effortless Experience, discusses research showing that less than 30% of organizations achieve full value from customer support AI investments. The conversation covers the "AI maturity gap" where adoption does not equal adaptation, why focusing solely on cost reduction limits AI potential, and barriers, including organizational readiness gaps and measurement challenges. DeLisi explains how high-performing organizations approach AI differently through operational changes beyond technology deployment, why low-effort experiences drive loyalty more than delight, and how contact centers can transform from cost centers into strategic growth engines.
Our final batch of America's Credit Unions GAC coverage- Glen speaks with Ncontracts' Stephanie Lyon about the shifting yet inevitable regulatory/compliance landscape. Also- another Domino falls on Paze's roadmap, and Illinois' interchange debacle proves too geeky for prediction markets- but not for a punk rock reference. Links related to this episode: Ncontracts' blog: https://www.ncontracts.com/nsight-blog Stephanie Lyon via LinkedIn: https://www.linkedin.com/in/stephanie-lyon-8a9b6257/ Paze's addition of Citi and Domino's: https://www.digitaltransactions.net/dominos-and-payrange-add-the-paze-wallet-option/ Taft Law's PayTech practice: https://www.taftlaw.com/services/practices/paytech-and-payment-systems/ Our prior GAC coverage, featuring TruStage's Stablecoin and Glia https://www.big-fintech.com/stablecoins-and-ai-need-we-say-more/ and CUltivate AI/ ACU's Economics Team https://www.big-fintech.com/chicken-wings-not-sharp-elbows/ LAST CHANCE! Join us at CU Unplugged, an unscripted, participant-powered gathering designed to foster unfiltered conversation on the topics participants deem most critical. The event is open to all credit union leaders, but the group will be kept intentionally small for maximum impact. Join us March 30 – April 2 at Visa's Market Support Center in San Francisco- Visit https://www.cu-unplugged.com/ to learn more and register. Follow us on LinkedIn: https://www.linkedin.com/company/best-innovation-group/ https://www.linkedin.com/in/jbfintech/ https://www.linkedin.com/in/glensarvady/
Continuing our Americas Credit Unions Government Affairs Conference coverage, Managing Director Brian Kaas discusses TruStage's new stablecoin designed specifically for credit unions, and CEO/Co-Founder Dan Michaeli shares data-driven insights from Glia's new Banking AI Benchmarks Report. Also- fintech's answer to the NBA Slam Dunk Competition. Links related to this episode: TruStage Stablecoin: https://www.trustage.com/business-solutions/stablecoin Glia's Banking AI Benchmarks Report: https://go.glia.com/banking-ai-benchmark-data-2026 CU Broadcast's segment recorded in DC with Glen, Anne Legg and Lou Grilli sharing their key GAC takeaways: https://www.cubroadcast.com/episodes/gac26-credit-union-industry-thought-leaders-share-their-top-gac-reflections Glen's November 2023 interview with Penny Finance Founder Crissi Cole: https://www.big-fintech.com/venturing-further-into-venturetech/ Our prior episode featuring GAC interviews with CUltivate AI (purpose-built AI for credit unions) and Americas Credit Unions' economics team: https://www.big-fintech.com/chicken-wings-not-sharp-elbows/ Check out CU Unplugged, an unscripted, participant-powered gathering designed to foster unfiltered conversation on the topics participants deem most critical. The event is open to all credit union leaders, but the group will be kept intentionally small for maximum impact. Join us March 30 – April 2 at Visa's Market Support Center in San Francisco- Visit https://flow.page/cu-unplugged to learn more and register. Join us for our next CU Town Hall- Wednesday March 18 at 3pm ET/Noon PT- a live and lively interactive conversation tackling the major issues facing credit unions. This month we'll discuss key takeaways from the recent Government Affairs Conference. If you missed GAC it's a great chance to catch up. If you were there, compare notes with your colleagues. The Town Hall is free to attend, but advance registration is required: https://www.cutownhall.com/ Follow us on LinkedIn: https://www.linkedin.com/company/best-innovation-group/ https://www.linkedin.com/in/jbfintech/ https://www.linkedin.com/in/glensarvady/
Send us a textToday Andrea Argueta is director of financial institution advisory at Glia, a company that focuses on providing credit unions and banks digital customer service tools and nowadays that means AI. So this show's focus is on the practical suite of tools Glia has working in some 400 credit unions, making Glia very probably the largest provider of AI tools to credit unions.Importantly, too, Argueta knows credit unions. That's because before coming to Glia she served as COO at Washington DC based IDB Global Federal Credit Union, an institution that serves the employees of the Inter-American Development Bank and their families and there are members in over 75 countries. At IDB Global she was a Glia customer and eventually that evolved into her joining the Glia team. In the show she tells about that journey and she also offers insights into what AI is really doing for credit unions today and the smart way for a credit union to join this party. In the show mention is made of two prior appearances on the show by Glia executives, Glia CEO Dan Michaeli in 2020 and Jake Tyler a year ago. Listen up.Like what you are hearing? Find out how you can help sponsor this podcast here. Very affordable sponsorship packages are available. Email rjmcgarvey@gmail.com And like this podcast on whatever service you use to stream it. That matters. Find out more about CU2.0 and the digital transformation of credit unions here. It's a journey every credit union needs to take. Pronto
Rick DeLisi is an author and Lead Research Analyst at Glia, an online leader in Digital Customer Service. Rick shares his expertise on integrating AI into work processes to achieve effortless interaction. Enjoy the listen. Along the way we discuss AI for All (5:00), AI and new product launch (10:00), AI Pre-Op (15:30), the Chainsaw Analogy (17:30), Communicating with Bots (19:00), flying the plane (21:00), dealing with the skeptics (21:45), Glia, Data Security, and Responsible AI (25:15), and the AI 24/7 Focus Group (31:15). Empower your teams and drive revenue @ Glia, AI Built for Community Impact This podcast is partnered with LukeLeaders1248, a nonprofit that provides scholarships for the children of military Veterans. Send a donation, large or small, through PayPal @LukeLeaders1248; Venmo @LukeLeaders1248; or our website @ www.lukeleaders1248.com. Music intro and outro from the creative brilliance of Kenny Kilgore. Lowriders and Beautiful Rainy Day.
Rick Delisi is a customer experience researcher, author, and thought leader who has spent over 20 years studying customer service from the rotary phone era to today's AI-powered solutions. As co-author of The Effortless Experience and Digital Customer Service, Rick has pioneered the understanding that reducing customer effort—not maximizing satisfaction—is the key to building loyalty.In this episode, we explore how AI is finally making it possible to eliminate bad customer service interactions entirely. Rick breaks down the concept of "AI for All" at Glia, where AI handles routine inquiries while empowering human agents with supercharged tools for complex, emotional interactions. We discuss the balance between efficiency and experience, the dangers of AI dependency, and why the best creativity now comes from asking questions no one's thought to ask before.
In this C.U. On The Show conversation, host Doug English talks with Andrea Argueta of Glia about approaches credit unions are using to incorporate AI into member service. They discuss where organizations are finding early operational benefits, how hand-offs to human agents are managed, and ways leaders are evaluating interaction strategies.Watch the episode on YouTube: https://youtu.be/lMEDO9WlS6gRead the episode summary on the ACT Advisors BlogEmail maris@act-advisors.com with any inquiries.
Send us a textWith so much talk around it, it was about time we dedicated a whole episode to AI – and boy, have we got a power-packed one for you! Meet Rick DeLisi who is leading AI adoption in an industry that almost everyone one of us has had a direct experience with – customer service. Rick is Lead Research Analyst at Glia, co-author of the bestselling business book The Effortless Experience and a multi-time contributor to the Harvard Business Review with more than 20 years of experience in the customer experience industry. This conversation underscores Rick's data-backed approach to understanding the gap between what leaders expect from AI and what actually happens in customer experience. Many organizations are wrestling with how to make AI a genuine advantage without falling into costly traps, and Rick's grounded research has spurred meaningful conversations at several leading companies. Hit play to get the lowdown! [4:29s] Evolution of customer service [10:13s] Growth of automation in customer service[19:02s] AI in customer service[28:27s] Organizations who are doing it well: ‘AI for all'[39:24s] Future drivers for AI adoption the ‘right way' [47:14s] Future of the customer service industry [51:06s] RWL: Read Rick's book ‘The Effortless Experience' Visit Glia at https://www.glia.com/ for more resources to help you elevate your customer service with the right adoption of AI.Connect with Rick on LinkedInConnect with Vinay on X and LinkedIn What did you think about this episode? What would you like to hear more about? Or simply, write in and say hello! podcast@c2cod.comSubscribe to us on your favorite platforms – Google Podcasts, Apple Podcasts, Spotify, Overcast, Tune In Alexa, Amazon Music, Pandora, TuneIn + Alexa, Stitcher, Jio Saavn and more. This podcast is sponsored by C2C-OD, your Organizational Development consulting partner ‘Bringing People and Strategy Together'. Follow @c2cod on Twitter, LinkedIn, Instagram, Facebook
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer's disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]
In this episode, Peter Maddison and Dave Sharrock welcome Rick Delisi, Lead Research Analyst at Glia and co-author of "The Effortless Experience" and "Digital Customer Service," to discuss how AI is transforming customer service in banking and credit unions.Rick reveals why the future of contact centers isn't about eliminating human interaction; it's about automating the routine so humans can focus on building real relationships. Learn how banks are breaking the age-old trade-off between efficiency and customer experience, and why starting with internal-facing AI tools is the safest path to transformation.Discover the surprising truth about which customer satisfaction metric actually predicts loyalty (hint: it's not what most companies are measuring), and why customer expectations for AI are shaped more by bad experiences with other companies than by anything your organization does.THREE KEY TAKEAWAYS:1. AI for Everyone, Not Just Customers: AI can transform your entire organization, from helping frontline agents with real-time guidance, to giving managers instant analysis capabilities, to enabling executives to make data-driven strategic decisions. The most successful implementations use AI across all levels: customers, agents, managers, and executives.2. Start Internal, Then Scale Outward: Begin with internal tools that help agents, managers, and executives first. This builds confidence, allows teams to experience the technology firsthand, and creates incremental improvements that build organizational trust. By the time you roll out customer-facing AI, your entire team understands and trusts the system.3. The best predictor of customer loyalty isn't satisfaction scores or Net Promoter Score, it's the Customer Effort Score. Ask customers, "How much effort was required for you to get what you needed?" after each interaction. Low-effort experiences drive loyalty, and this metric gives you actionable insights into where to improve your service processes.CONTACT US:Email: feedback@definitelymaybeagile.comDefinitely Maybe Agile explores the complexities of adopting new ways of working at scale, covering digital transformation, agile practices, and DevOps in enterprise environments.#AI #CustomerService #Banking #DigitalTransformation #ContactCenter #CreditUnions #CustomerExperience #Glia #FinancialServices #AgileTransformation
Host Eitan Koter opens this episode with Rick DeLisi, author and longtime customer loyalty researcher at GLIA, an interaction platform for banks and credit unions. Rick has spent years studying how everyday conversations with customers shape whether they stay or leave.He starts simple. People want what they want, their way, right now. That idea runs through the whole talk. Rick explains how to meet that bar by pairing quick, automated help for routine questions with a warm handoff to a person when things get complex.They get clear on measurement. Many teams launch AI without proving it works. Rick shares how to track real outcomes, not just fewer calls. Think cost to serve, loyalty signals, and what contact center patterns can tell the rest of the business, including marketing and product.Expect a plain take on trust. Rick suggests it is less about creating big trust moments and more about avoiding the small missteps that chip away at it. He shows how a smooth online to human transition, where the agent already knows who the customer is and why they reached out, can change the whole tone of an interaction.Listeners also hear the one question that best predicts future loyalty after a service moment, how much effort did that take. It is direct, easy to ask, and tells leaders where friction actually lives.Finally, Rick separates customer facing AI from internal AI. He covers how frontline teams can use AI to summarize, surface themes, and answer leadership questions in minutes, using the data from every conversation.If you lead service, marketing, or product, this chat gives you a simple path. Reduce effort, route the right way, measure what matters, and use what customers already told you to guide the next move.Website: https://www.vimmi.net Email us: info@vimmi.net Podcast website: https://vimmi.net/mastering-ecommerce-marketing/ Talk to us on Social:Eitan Koter's LinkedIn | Vimmi LinkedIn | YouTube Guest: Rick DeLisi, Author and Lead Research Analyst at GliaRick DeLisi's LinkedIn | Glia
This is a recording of a New Jewish Narrative webinar from August 25th, 2025. Experts share updates on the evolving humanitarian situation in Gaza. Featuring: Dr. Tarek Loubani, a medical doctor and founder of the Glia project, which provides medical aid and services in war-torn regions, Palestine the first among them. He is currently working at a hospital in Gaza. Dr. Lee Mordecai, an Israeli historian who is well known for his recent documentation of war crimes in Gaza, especially as they relate to starvation. Karam Al-Shanti, a native Gazan who works for the Red Cross and is currently based in Belgium. This webinar was cosponsored by New Jewish Narrative, T'ruah: The Rabbinic Call for Human Rights, Satyam, Combatants for Peace, Rabbis for Human Rights, Partners for Progressive Israel, Mizrahi Civic Collective, and Smol Emuni. Moderated by: Annie Kantar, award-winning Israeli writer, and Noam Shelef, New Jewish Narrative's Vice President for Communications.
Die Themen in den Wissensnachrichten: +++ Sozialer Abstieg beeinflusst Wahlverhalten +++ Viele US-Amerikaner schätzen klimaschädliches Verhalten falsch ein +++ Auch Katzen werden dement +++**********Weiterführende Quellen zu dieser Folge:Update ErdeDownward Mobility and Far-Right Party Support: Broad Evidence/ Comparative Political Studies, 27.06.2025Climate action literacy interventions increase commitments to more effective mitigation behaviors/ PNAS Nexus, 09.06.2025Amyloid-Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease/ European Journal of Neuroscience, 11.08.2025Linalool-triggered plant-soil feedback drives defense adaptation in dense maize plantings/ Science, 14.08.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
“12 UN Relief Works Agency staff members are accused of involvement in Hamas' attack against Israel,” reports NPR. “Details Emerge on U.N. Workers Accused of Aiding Hamas Raid,” announces The New York Times. “Hamas Military Compound Found Beneath U.N. Agency Headquarters in Gaza,” claims The Wall Street Journal. In January 2024—literally on the same day the International Court of Justice deemed Israel was committing “plausible genocide”—a number of sensationalistic headlines broke across U.S. media, namely The Wall Street Journal and New York Times, telling us in 40-point font that the United Nations Relief and Works Agency (UNRWA), the single most important supplier of food and medical aid in Palestine, was in fact a front for "Hamas." Western audiences were told that, based on “Israeli intelligence”, 12 workers at the agency may have been involved in the attacks on October 7, 2023, and, in another blockbuster claim, that “Around 10% of Palestinian aid agency's 12,000 staff in Gaza have links to militants, according to intelligence dossier.” Given this history, the logic went, who knows how else the agency might be operating at the behest of Hamas? It would have been a major revelation if there were any evidence to support it. But there wasn't and the story was later dropped, walked back or ignored by the media. But the damage was done: President Biden quickly defunded UNRWA and Israel criminalized it, helping fast track mass starvation in Gaza. So why did media outlets publish so many breathless and lurid headlines about Israel's claims without an ounce of independent confirmation? To what extent, if any, have outlets acknowledged their journalistic and moral recklessness? And how has this contributed to the mass starvation, immiseration, and wholesale murder of the population of Gaza? On this episode, Part I of our two-part season finale on “The Importance of Seriousness, or Why Palestinians Can't Be Witness to Their Own Genocide,” we examine the role of legacy news media in inciting the starvation of millions of Palestinians in Gaza, the racist double standard of what sources and experts can be trusted and the broader incitement campaign against the UN Relief and Works Agency which directly caused today's mass starvation in Gaza. Our guest is Moureen Kaki, Head of Mission at Glia.
Justin DiPietro, Co-Founder & Chief Strategy Officer of Glia, shares how they are leveraging AI to enhance the customer experience in the highly regulated world of financial institutions.Topics Include:Glia provides voice, digital, and AI services for customer-facing and internal operationsBuilt on "channel-less architecture" unlike traditional contact centers that added channels sequentiallyOne interaction can move seamlessly between channels (voice, chat, SMS, social)AI applies across all channels simultaneously rather than per individual channel700 customers, primarily banks and credit unions, 370 employees, headquartered in New YorkTargets 3,500 banks and credit unions across the United States marketFocuses exclusively on financial services and other regulated industriesAI for regulated industries requires different approach than non-regulated businessesTraditional contact centers had trade-off between cost and quality of serviceAI enables higher quality while simultaneously decreasing costs for contact centersNumber one reason people call banks: "What's my balance?" (20% of calls)Financial services require 100% accuracy, not 99.999% due to trust requirementsUses AWS exclusively for security, reliability, and future-oriented technology accessReal-time system requires triple-hot redundancy; seconds matter for live callsWorks with Bedrock team; customers certify Bedrock rather than individual featuresShowed examples of competitors' AI giving illegal million-dollar loans at 0%"Responsible AI" separates probabilistic understanding from deterministic responses to customersUses three model types: client models, network models, and protective modelsTraditional NLP had 50% accuracy; their LLM approach achieves 100% understandingPolicy is "use Nova unless" they can't, primarily for speed benefitsParticipants:Justin DiPietro – Co-Founder & Chief Strategy Officer, GliaFurther Links:Glia WebsiteGlia AWS MarketplaceSee how Amazon Web Services gives you the freedom to migrate, innovate, and scale your software company at https://aws.amazon.com/isv/
Raúl Incertis, médico de urgencias y anestesista, voluntario de la ONG canadiense GLIA habla de la situación en el hospital Nasser de la Franja de Gaza, lugar donde trabaja: "El hospital cuenta con 270 camas y tiene ahora unos 700 pacientes ingresados que están por los pasillos". "Se han tenido que abrir UCI improvisadas que están llenas, el hospital ha sido atacado seis veces desde que llegué", comenta el médico."Llevo casi cuatro meses aquí [...] si hay una carnicería -un evento de múltiples víctimas donde llegan demasiados heridos al hospital como para que el hospital los pueda atender en condiciones normales- estamos hablando de que todos los días se produce en este hospital un 11M", declara Incertis. Sobre la desnutrición, el médico afirma: "Todos los pacientes que veo y que atiendo, todos sin excepción, están desnutridos. Todos los pacientes, todos mis compañeros, médicos, enfermeros, todos han perdido una media entre 25 y 30 kilos desde que empezó la venganza israelí". También denuncia los precios de la comida: "Una lata de atún te puede costar 10 dólares y a veces no la encuentras en el mercado. Un kilo de harina está aproximadamente por 30 dólares. Un kilo de arroz también, 25 o 30 dólares".Tras los meses de calvario, el médico ha tomado la decisión de irse de Gaza: "Regreso esta semana que viene porque no puedo más. Mentalmente estoy muy cansado, difícilmente soy funcional, no tengo energía, tengo ansiedad. El hospital tiembla varias veces por la noche porque las bombas son muy fuertes y caen muy cerca del hospital, con lo cual no duermes. Te despiertas unas siete, ocho, diez veces por la noche con cada bomba que cae cerca". De todas formas Raúl Incertis no pierde la esperanza: "Cuando me recupere, si los israelíes me dejan, volveré con energía". Entrevista completa en RNE Audio.Escuchar audio
What will it take for the Canadian government to recognize what is happening in Palestine as a genocide? This growing coalition aims to find out.Three members of United Against Genocide join the studio to explain why that key word matters so much, and what they're doing to add to the pressure politicians must be feeling at this point. They share what its been like meeting with high ranking officials, and what their expectations of new PM Carney were heading into the G7.They openly challenge the notion that this is simply a humanitarian crisis that needs better handling or funding by exposing the Gaza Humanitarian Foundation's role in this horrific stage of the genocide. Guests:Dr. Ben Thompson, healthcare provider and cofounder of Eyewitness Gaza. Ben has visited Gaza almost annually since 2012 and been suspended from his job for advocating for peace.Dorotea Gucciardo, Ph.D, Director of Development for GLIA, and cofounder of Eyewitness Gaza.Alex Neve, International Human Rights lawyer and former Secretary General for Amnesty International Canada.Hosted by: Jessa McLeanCall to Action: Tell PM Carney to Stop Covering for Israel (PETITION)Related Episodes: Courage Needed to Advocate for Palestine (October 6, 2023) with activist and scholar Ghada Sasa on navigating Parliament Hill for Palestine. Disrupting Politics (December 20, 2023) with Dimitri Lascaris. A discussion on the role our politicians play and how they can be held accountable. More Resources: UN Resolutions on Genocide PreventionCBC: Dr. Ben Thompon Doxxed and Suspended for Palestinian PostsIsraeli, US-backed Gaza aid group must end, say 130 charitiesMedia Advisory: United Against Genocide
Nos cuenta la última hora en el territorio de Gaza Raúl Incertis, anestesista y médico en el hospital Nasser en el sur de la franja GAZA. Es voluntario de la ONG médica anadiense Glia.Más de tres millones de españoles viven fuera de nuestro país, según el Padrón de Españoles Residentes en el Extranjero. Muchos se fueron, se van, buscando las oportunidades de trabajo que no encuentran en aquí. Otros se van a formarse, gracias a las becas de estudios. Marina Perezagua, ha sido profesora en la Universidad de Nueva York durante más de 20 años y en junio se regresa a España.La educación es una fuente constante de debate. Toda sociedad tiene unos pilares básicos educativos... y además el sector va asumiendo nuevas realidades y necesidades, como la inclusión de las pantallas en las aulas, o los cambios de metodología, que en estos últimos tiempos priorizan más la enseñanza libre. Nos vamos a ir a Noruega, allí una profesora española de 23 años, Noah Toboada está trabajando como tutora de niños de diez años en un colegio internacional, y está aprovechando sus redes sociales para explicar su día a día como profesora.Con el objetivo de dar a conocer en qué consiste la investigación este 20 de mayo se celebra el Día Internacional del Ensayo Clínico. España es el primer país de Europa y el tercero del mundo, trás Estados Unidos y China, en ensayos clínicos que salvan la vida a pacientes que no responden a tratamientos convencionales. Nos cuenta María Manjavacas.
Hablamos con Raúl Incertis, anestesista y médico de urgencias en el hospital Nasser en el sur de la franja de Gaza. Es voluntario de la ONG médica canadiense Glia. Nos cuenta el estado actual de los hospitales en Gaza.
Nos cuenta la última hora en el territorio de Gaza Raúl Incertis, anestesista y médico en el hospital Nasser en el sur de la franja GAZA. Es voluntario de la ONG médica anadiense Glia.Más de tres millones de españoles viven fuera de nuestro país, según el Padrón de Españoles Residentes en el Extranjero. Muchos se fueron, se van, buscando las oportunidades de trabajo que no encuentran en aquí. Otros se van a formarse, gracias a las becas de estudios. Marina Perezagua, ha sido profesora en la Universidad de Nueva York durante más de 20 años y en junio se regresa a España.La educación es una fuente constante de debate. Toda sociedad tiene unos pilares básicos educativos... y además el sector va asumiendo nuevas realidades y necesidades, como la inclusión de las pantallas en las aulas, o los cambios de metodología, que en estos últimos tiempos priorizan más la enseñanza libre. Nos vamos a ir a Noruega, allí una profesora española de 23 años, Noah Toboada está trabajando como tutora de niños de diez años en un colegio internacional, y está aprovechando sus redes sociales para explicar su día a día como profesora.Con el objetivo de dar a conocer en qué consiste la investigación este 20 de mayo se celebra el Día Internacional del Ensayo Clínico. España es el primer país de Europa y el tercero del mundo, trás Estados Unidos y China, en ensayos clínicos que salvan la vida a pacientes que no responden a tratamientos convencionales. Nos cuenta María Manjavacas.
Hablamos con Raúl Incertis, anestesista y médico de urgencias en el hospital Nasser en el sur de la franja de Gaza. Es voluntario de la ONG médica canadiense Glia. Nos cuenta el estado actual de los hospitales en Gaza.
Subscribe now for an ad-free experience and much more content! One last news roundup without Derek, but Danny and Alex Jordan of the Quincy Institute are on the case! This week: the RSF announces plans to form a parallel government in Sudan (1:33); US-Iran nuclear negotiations continue in Oman (7:21); the US and Saudi Arabia discuss giving the Kingdom access to nuclear technology (14:19); the Trump trade war continues despite him dialing back certain tariffs (18:40); Xi Jinping tours Southeast Asia (22:44); President Nayib Bukele of El Salvador visits the White House amid the controversy of Kilmar Ábrego García's deportation (27:15); ICE is ramping up the arrest of pro-Palestine voices in the US (31:14); center-right candidate Daniel Noboa wins the presidential election in Ecuador (32:56); American envoy Steve Witkoff says a peace deal between Ukraine and Russia is imminent (34:36) and President Vladimir Zelenskyy appears on 60 Minutes (40:42); and the Israeli government announces that it will escalate its attack on Gaza (43:13). Danny then speaks with Afeef Nessouli, a volunteer currently in Gaza working with Glia, a medical organization that “empowers low-resource communities to build sustainable, locally-driven healthcare projects.” Please consider donating to Glia to help Afeef and Palestinians doing medical work in Gaza. Afeef also works with Shabab Gaza, a local project that provides food for victims of the genocide. You can donate if you DM them @shababgaza1 on Instagram. If you'd like to follow Afeef please check out his Instagram handle @afeefness, where he's been sharing his experiences in Gaza. And catch Alex Jordan on X/Twitter @alexjordanatl and on the Quincy Institute's upcoming YouTube program “Always at War," which he will co-host with Courtney Rawlings. Learn more about your ad choices. Visit megaphone.fm/adchoices
One last news roundup without Derek, but Danny and Alex Jordan of the Quincy Institute are on the case!This week: the RSF announces plans to form a parallel government in Sudan (1:33); US-Iran nuclear negotiations continue in Oman (7:21); the US and Saudi Arabia discuss giving the Kingdom access to nuclear technology (14:19); the Trump trade war continues despite him dialing back certain tariffs (18:40); Xi Jinping tours Southeast Asia (22:44); President Nayib Bukele of El Salvador visits the White House amid the controversy of Kilmar Ábrego García's deportation (27:15); ICE is ramping up the arrest of pro-Palestine voices in the US (31:14); center-right candidate Daniel Noboa wins the presidential election in Ecuador (32:56); American envoy Steve Witkoff says a peace deal between Ukraine and Russia is imminent (34:36) and President Vladimir Zelenskyy appears on 60 Minutes (40:42); and the Israeli government announces that it will escalate its attack on Gaza (43:13). Danny then speaks with Afeef Nessouli, a volunteer currently in Gaza working with Glia, a medical organization that “empowers low-resource communities to build sustainable, locally-driven healthcare projects.”Please consider donating to Glia to help Afeef and Palestinians doing medical work in Gaza. Afeef also works with Shabab Gaza, a local project that provides food and sometimes produce for victims of the genocide. I have personally backed boxes of rice for families. You can donate if you DM them @shababgaza1 on Instagram.And Catch Alex Jordan on X/Twitter @alexjordanatl and on the Quincy Institute's upcoming YouTube program “Always at War, which he will co-host with Courtney Rawlings.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
ReferencesCells. 2020 Feb 18;9(2):471.Mol Neurobiol. 2019. Volume 56. 5436–5455.Glia. 2023 Nov;71(11):2679-2695Goffin and King. 1966. "Goin' Back" Byrds 1967 coverhttps://music.youtube.com/watch?v=i849OKrpPms&si=Gjmsjp0rQpLbmwxCKing, C. 1971. "Tapestry" lphttps://music.youtube.com/watch?v=SyQ-TgA6bQk&si=7L23vJZolSbkZMR1Mozart, WA . 1782-85'. "The Six Haydn Quartets"https://music.youtube.com/watch?v=dzzOzaWia90&si=QfDkHMP8Kzz_mtpW
We've talked about glia and sleep. We've talked about glia and neuroinflammation. We've talked about glia in the brain fog that can accompany COVID or chemotherapy. We've talked about the brain's quiet majority of non–neuronal cells in so many different contexts that it felt like it was high time for us to take a step back and look at the bigger picture. After all, glia science was founded here at Stanford in the lab of the late, great Ben Barres.No one is better suited to take us through this history and lead us to the frontiers of the field than today's guest, Brad Zuchero. A former Barres lab postdoc, and now an emerging leader in this field in his own right, Brad gives us an overview of our growing understanding of the various different kinds of glia and their roles in brain function, and shares the exciting discoveries emerging from his lab — including growing evidence of a role for myelin in Alzheimers disease.Learn MoreNeuroscientist Ben Barres, who identified crucial roles of glial cells, dies at 63 (Stanford Medicine, 2017)How exciting! Study reveals neurons rely on glial cells to become electrically excitable (Stanford Neurosurgery, 2024)Unlocking the secrets of myelin repair (Wu Tsai Neurosciences Institute, 2024)Q&A: Linking sleep, brain insulation, and neurological disease with postdoc Daniela Rojo (Knight Initiative for Brain Resilience, 2023)From angel to demon: Why some brain cells go ‘bad' (Scope Blog, 2021)Get in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the Knight Initiative for Brain Resilience at Wu Tsai Neuro.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
We're kicking off our new season with a deep dive into one of neuroscience's most fascinating mysteries: sleep. This unconscious third of our lives isn't just about rest – it's absolutely critical for brain health, memory consolidation, and overall well-being. But here's where it gets intriguing: recent research suggests that increased napping as we age might be an early warning sign of Alzheimer's disease.To unpack this complex relationship, we're thrilled to welcome back Erin Gibson, assistant professor of psychiatry at Stanford School of Medicine and Wu Tsai Neuro affiliate. We'll explore whether age-related sleep changes are potential contributors to brain degeneration or valuable early indicators of otherwise invisible brain disorders, possibly opening doors for early intervention.We'll also learn about Gibson's research, supported by the Knight Initiative for Brain Resilience at Wu Tsai Neuro, which investigates how myelin—the insulation of our nerve cells—could be a key missing link in understanding the relationship between sleep and brain health.Join us for an enlightening discussion that might just change how you think about your nightly slumber and its profound impact on long-term cognitive function. Mentioned on the ShowDopamine and serotonin work in opposition to shape learningGibson Lab at Stanford University School of MedicineSurprising finding links sleep, brain insulation, and neurodegeneration | Knight InitiativeExtended napping in seniors may signal dementia | UCSFRelated EpisodesRespect your Biological Clock | Erin GibsonWhy sleep keeps us young | Luis de LeceaWhy new Alzheimer's drugs don't work | Mike GreiciusGet in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker and research assistance by G Kumar. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
For more information, visit https://thecirsgroup.com Today we have a special guest! Dr. Dayan Goodenowe is a researcher that has unlocked the power of plasmalogens and thankfully, this is something that can be a real game changer for people struggling with CIRS, or Chronic Inflammatory Response Syndrome. We cover what they are, where they come from, how to try them for yourself, and more. Check out the time stamps and links below, and for more information, support, and resources in your own CIRS healing journey, visit TheCIRSGroup.com TIME STAMPS: 0:00 Intro and disclaimer 1:28 What are plasmalogens? 6:20 What do plasmalogens do? 10:20 How Dr. Goodenowe started working with plasmalogens 13:10 Glia and Nuero: what are the differences? 16:47 Titrate up slowly and carefully 18:40 Jacie's experience with plasmalogens, and how plasmalogens help even in exposure 23:30 Getting to baseline to build resilience 26:45 Side effects to look out for when starting out 21:10 Blood test to determine your needs/deficiencies 38:24 How to work with Dr. Goodenowe or purchase his products HELPFUL LINKS MENTIONED: Dr. Goodenowe's website: https://drgoodenowe.com/ His Prodrome website to purchase plasmalogens: https://prodrome.com/ The CIRS Summit: https://thecirssummit.com/ The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Pre-order Jacie's book! https://a.co/d/8ZKCqz0 Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.
Neurons have long enjoyed a kind of rock star status. We think of them as the most fundamental units of the brain—the active cells at the heart of brain function and, ultimately, at the heart of behavior, learning, and more. But neurons are only part of the story—about half the story, it turns out. The other half of the brain is made up of cells called glia. Glia were long thought to be important structurally but not particularly exciting—basically stage-hands there to support the work of the neurons. But in recent decades, at least among neuroscientists, that view has faded. In our understanding of the brain, glia have gone from stage-hands to co-stars. My guest today is Dr. Nicola Allen. Nicola is a molecular neuroscientist and Associate Professor at the Salk Institute in La Jolla, California. She and her lab study the role of glial cells—especially astrocytes—in brain function and dysfunction. Here, Nicola and I talk about how our understanding and appreciation of glial cells has changed. We do a bit of Brain Cells 101, reviewing the main division between neurons and glia and then sketching the subtypes within each category. We discuss the different shapes and sizes of glial cells, as well as the different functions. Glia are an industrious bunch. They're involved in synapse formation and pruning, the production of myelin, the repair of injuries, and more. We also talk about how glial cells have been implicated in various forms of brain dysfunction, from neurodegeneration to neurodevelopmental syndromes. And how, as a result, these cells are attracting serious attention as a site for therapeutic intervention. Well, it's that time of year again folks. Applications are now open for the 2025 Diverse Intelligences Summer Institute, or DISI. This is an intense program—highly interdisciplinary, highly international—for scholars and storytellers interested in all forms and facets of intelligence. If you like thinking about minds, if you like thinking about humans and animals and plants and AIs and collectives and ways they're alike and different—you would probably like DISI. For more info, check out disi.org—that's D-I-S-I dot org. Review of applications begins March 1st, so don't dally too too long. Alright friends—on to my conversation with Dr. Nicola Allen. Enjoy! Notes and links 3:00 – Correction: “glia” actually comes from the Greek—not the Latin—for “glue.” 3:30 – See this short primer on glia by Dr. Allen and Dr. Ben Barres. For a bit of the history of how glial cells were originally conceived, see this article on Ramón y Cajal's contributions to glia research. 10:00 – On the nascent field of “neuroimmunology,” see here. 14:00 – On the idea that “90% of brain cells are glia” see this article by (former guest) Suzana Herculano-Houzel. 18:00 – The root “oligo” in “oligodendrocyte” means “few” (and is thus the same as the “olig” in, e.g., “oligarchy"). It is not related to the “liga-” in “ligament.” 28:00 – On the idea that the glia-neuron ratio changes as brains grow more complex, see again the article by Dr. Herculano-Houzel. 30:00 – See Dr. Allen's paper on the idea of glia as “architects.” See also Dr. Allen's paper on the idea of glia as “sculptors.” 33:00 – See Dr. Allen's paper on the idea of the “tripartite synapse.” 42:00 – A recent paper reviewing the phenomenon of adult neurogenesis. 48:00 – See Dr. Allen's recent review of the role of astrocytes in neurodegeneration. 51:30 – A recent article on the roles of APOE in Alzheimer's. Recommendations Glia (2nd edition), edited by Beth Stevens, Kelly R. Monk, and Marc R. Freeman Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com. For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).
The biology that gives us Autism allows us to be comfortable within ourselves.Our biology orients the Autistic towards our internal state. This is more comfortable for the Autistic in comparison to the outside world. In this episode, we cover brain regions, networks, and internal calculators. All humans use these biological calculators. However, based on the living organisms unique structure of brain regions and networks (connections), it is easy to understand why people are different.Epinephrine & Glia https://www.sciencedirect.com/science/article/pii/S009286741930621XOther Resources: Autism and Adaptive Responses https://youtu.be/Zj3_e6ZjCGkAutism and Default Mode Network https://youtu.be/9CqyH4woB34Autism and Salience Network https://youtu.be/9ZbTztb3al8Autism and B.3 https://youtu.be/Ov_Bw--zzrQ00:00 - Introduction00:42 - Biology and Autistic Comfort03:05 - Salience Network Explanation05:06 - Attention Management in Autism08:35 - Default Mode Network in Autism09:47 - Introducing Internal Calculators & Neuromodulators; Neuroplasticity10:52 - Biological Responses in Autistic Behavior14:02 - Effort and Energy: The Role of Internal Calculators; Calculator for Effort vs. Outcome17:07 - Social Interaction and Energy Use20:23 - Dopamine and Internal Calculators; Reward Prediction Error as an Internal Calculator25:18 - Internal Calculators and Societal Norms; Impact of Social Expectations on Internal Calculators; NeuroplasticityX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
Send us a textAI - it's the word on every lip in credit union land as most institutions scramble to find ways to usefully harness AI.And then there is Glia, the company known for contact center tools that are at work in many credit unions and now Glia has debuted a suite of AI powered contact management tools that are ready to use now.If you've been wondering when AI would get real for credit unions, know it already is real at many Glia customers.Glia unveiled its AI collection at its Interact 2024 user conference in October and on the show today is Jake Tyler, founder of Finn AI which Glia bought a few years ago and Tyler joined Glia in that transaction.Glia's approach to AI is shaped by the company's focus on contact centers in FIs. In the show Tyler explains how that focus impacts Glia's AI development and in that vein he stressed that Glia is committed to delivering “responsible AI.”Listen up.Like what you are hearing? Find out how you can help sponsor this podcast here. Very affordable sponsorship packages are available. Email rjmcgarvey@gmail.com And like this podcast on whatever service you use to stream it. That matters. Find out more about CU2.0 and the digital transformation of credit unions here. It's a journey every credit union needs to take. Pronto
Nick Thorburn is a singer, songwriter and multi-instrumentalist residing in Los Angeles. Nick has fronted and co-founded bands such as The Unicorns, Human Highway, Mister Heavenly and Islands. Nicks newest single Hold (a song for Aaron Bushnell) is dedicated to Aaron Bushnell, an active US serviceman who publicly took his life in an act of extreme protest of the United States support of Israel in the Israel-Hamas war. Nick tells us why Aaron Bushnell's self-immolation deeply affected him, how it motivated him to write Hold and why he chose to give all the proceeds to Glia, the life-saving medical support initiative on the ground in Gaza. Nick shares the root of his protesting spirit and the two discuss why protest why it's an important act of shaking us awake. He tells us why he included Bushnell's final words in Hold, and how those words informed Nicks lyrical process. Joe and Nick discuss the importance of showing solidarity in our current socio-political-war mongering climate and we listen to Hold (a song for Aaron Bushnell). Hold (a song for Aaron Bushnell) Episode supported by Izotope Episode supported by Distrokid
Glia's Lead Research Analyst Rick DeLisi returns to Bankadelic to introduce the 2024 Unified Interactions Index, which goes beyond measuring customer experience to also incorporate efficiency and effectiveness in contact centers. Using data from data from more than 3 billion customer interactions, the index represents a valuable tool to help financial institutions know where they stand among their peers. Rick also shares his views on how responsible AI plays out in the real world.
Science is not some purely rationalist endeavor that exists in an isolated realm of objective observations and hard data that can deliver absolute truths. It is built on and intertwined with the modes of analysis, intellectual history, and ways of knowing in the humanities. 0:00 Intro 2:19 Part 1 –– Metaphors We Live By 5:52 Part 2 –– Metaphors in Science, an Ancient Paradox 10:32 Part 3 –– Embryology 23:10 Part 4 –– The Clockwork Universe 32:04 Part 5 –– The History of a Dead Metaphor: Cell 44:00 Part 6 –– Black Holes 51:10 Part 7 –– The Body 57:50 Part 8 –– Pain, in 78 Adjectives 1:05:29 Part 9 –– Natural Selection 1:09:47 Part 10 –– A New Metaphor for Science 1:20:22 Part 11 –– The Solar System Model of the Atom 1:24:35 Part 12 –– Uniformitarianism 1:31:35 Part 13 –– Glia, the Gendering of a Cell 1:39:15 Part 14 –– Light Bulbs and Seeds 1:46:04 Part 15 –– War and Disease, the Domination of a Metaphor 1:51:26 Part 16 –– Social Darwinism 1:55:05 Part 17 –– The Universe 2:02:08 Part 18 –– Anthropomorphism An Inexact Science is a production of The World According to Sound. It's part of our series, “Ways of Knowing,” audio works dedicated to humanities research and thought. It was made in collaboration with the University of Chicago's Institute on the Formation of Knowledge. Special thanks to Shadi Bartsch-Zimmer, who spearheaded the project at the University of Chicago. Editorial support from Hans Buetow. Academic advising by Andrew Hicks. Voicing work by Tina Antolini. Mathematical consultant, Steven Strogatz. Intro music by our friends, Matmos. And to see a complete list of musicians used in this show, visit our website: www.theworldaccordingtosound.org
Dan Michaeli is the co-founder and CEO of Glia, a digital customer service platform that seamlessly integrates various modes of communication into one “channel-less” interface. In other words, customer interactions evolve as the conversations do in the digital-first world: moving easily between voice and screen, virtual AI assistance, and live humans - even securely sharing screens. I've been lucky enough to see this platform in action and I was SO impressed that I had to bring Dan on the podcast. He's been at the forefront of AI and customer experience for over a decade, and he talks to me about the balance of efficiency and human responsibility, the use of “digital body language,” and the importance of an omnichannel experience. Learn more about GliaFollow Dan on LinkedIn
Episode Summary This week on Live Like the World is Dying, Inmn talks to Mike and Alex from Distributed Medical Device Manufacturing about the role of anarchists in manufacturing and their work manufacturing medical devices, and specifically, about their work manufacturing tourniquets with 3D printers and industrial sewing machines. Guest Info Find Distributed Medical Device Manufacturing (DMDM) at DMDM.icu or support their funding campaign on Give Butter at https://givebutter.com/pqygLj DMDM is a small non-profit based in Tucson, Arizona, USA. We formed as an offshoot of MADR in order to begin exploring how regulatory compliant aid can be manufactured outside the existing profit driven, hierarchical medical device manufacturing industry. Our mission is to make high quality, FDA compliant CAT style tourniquets based on the GLIA design to ensure our communities have access to life saving supplies in the event of trauma events and supply chain breakdowns. Host Info Inmn can be found on Instagram @shadowtail.artificery Publisher Info This show is published by Strangers in A Tangled Wilderness. We can be found at www.tangledwilderness.org, or on Twitter @TangledWild and Instagram @Tangled_Wilderness. You can support the show on Patreon at www.patreon.com/strangersinatangledwilderness.
Glen speaks with Glia's Jake Tyler about his firm's approach to delivering ethical AI solutions to financial institutions. Also- Finovate Best of Show winners, and the continuing crisis in card interchange. Links related to this episode: Glia: https://www.glia.com/news/glia-launches-first-responsible-ai-platform-purpose-built-for-financial-institutions Demo videos for Finovate Spring's Best of Show winners: https://finovate.com/videos/?filtertype=&showtypes=FinovateSpring&videostartyear=2024&showletters=A-Z Our November 2022 interview with Remynt founder Gwyneth Borden: https://www.big-fintech.com/Media?p=americas-got-access-vegas-has-crowds Glen's blog on the flurry of state interchange legislation: Last week's BIGCast on Apple Intelligence and proposed AI legislation: https://www.big-fintech.com/Media?p=algorithmic-discrimination-and-other-sci-fi-sounding-terms-relevant-today Check out BIG's AI Development offerings, enabling credit unions to streamline operations, amplify member experiences and capture new opportunities in the digital financial landscape. https://www.big-fintech.com/Products-Services/AI-Development Find us on X and BlueSky at @bigfintech, @jbfintech and @154Advisors (same handles for both) You can also follow us on LinkedIn: https://www.linkedin.com/company/best-innovation-group/ https://www.linkedin.com/in/jbfintech/ https://www.linkedin.com/in/glensarvady/
It's no secret that rivers winding through major cities have been reshaped by human hands. Where wildlife and marshes once existed, gray sidewalks and bleak straight-lined tributaries have blossomed. Now, some cities are implementing floating wetlands — native plant life on a body of biodegradable materials that bobs on top of the water — to address a budding desire to see animals and greenery return to their rivers. In this podcast episode, Jenaye Johnson speaks with scientists and community members in Chicago about the Wild Mile — the city's biggest floating wetland to date. Join her as she winds down the Chicago River, explores the wetlands and discusses the future of new animal habitats and clean water in our urban spaces. And check out the associated article on Scienceline: https://scienceline.org/2024/06/wilding-city-rivers/ Music used: "Glue&Glia" by Rah Hite | CC BY 4.0 "Floating Wetlands" by Rah Hite | CC BY 4.0 "Lo Margin" by Blue Dot Sessions | CC BY-NC 4.0 "The Maison" by Blue Dot Sessions | CC BY-NC 4.0
Even after several rounds of revolution in technology, call centers still conjure up nightmares of voice mail hell and endless wait times for consumers. Nor is fixing these problems as simple as moving to the cloud or plugging in some AI. Dan Michaeli, the CEO and Co-Founder of Glia, walks us through how to redefine customer interaction and bring support to higher (and previously unattainable) levels.
Dr. Marissa Scavuzzo is an HHMI Hanna H. Gray Fellow at Case Western Reserve University School of Medicine. Her research focuses on enteric glia regulation in the healthy and diseased gut. She talks about how glial cell subtypes affect intestinal motility and her experience receiving NYSCF and HHMI fellowships. She also talks about bringing science to underserved schools in Cleveland.