Podcasts about Hadler

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Best podcasts about Hadler

Latest podcast episodes about Hadler

FreepCast
The NEW FreepCast, Episode 7-Meet Calli Hadler!

FreepCast

Play Episode Listen Later Jul 18, 2024 20:05


In the latest episode of The Free Press' podcast, "FreepCast," summer intern Callie Hadler talks about being the new kid covering the biggest story to hit the region in years. Hadler, a journalism student from the University of Minnesota, had only been part of the newsroom for a few weeks when she was told to help cover a story that wound up on the national news: the floods and the crisis at the Rapidan Dam. Hadler, who is from Annandale, also talks with hosts Joe Spear and Robb Murray about why she chose to get into journalism and the challenges her generation face in a world with seemingly unending waves of negative news.

SWR2 Kultur Info
Bianka Hadler und Sonja Voß-Scharfenberg und ihr Buch vom Altsein

SWR2 Kultur Info

Play Episode Listen Later Apr 30, 2024 16:00


Bianka Hadler und Sonja Voß-Scharfenberg haben gemeinsam ein Buch über das Altern geschrieben. Wenn sie daraus in Buchhandlungen lesen, sind die Räume rappelvoll. Alter, Pflege, Abhängigkeit von anderen – das scheint viele Menschen zu beschäftigen.

Views From The Bus - Brought to you by Procopio
Ron Hadler, Red Door Interactive

Views From The Bus - Brought to you by Procopio

Play Episode Listen Later Sep 20, 2023 38:06


In today's episode of Views From the Bus, Bob gets to something on the top of all business minds, Artificial Intelligence (AI) with Ron Hadler of Red Door Interactive! Ron is the VP of innovation for Red Door Interactive, San Diego's best full service agency. And our topic today is all about the brain in front of the change that's coming with Gen AI.  If you missed the previous presentation Ron did for our Ask the Expert series on Gen AI a few months ago, here's your second chance! 

Hope, Nevada
Give Hope Foundation with Elisabeth Hadler

Hope, Nevada

Play Episode Listen Later Jun 4, 2023 25:58


Give Hope Foundation This week we had a conversation with Elisabeth Hadler, marketing director for the Give Hope Foundation. Give Hope is a volunteer run organization providing assistance, hope, relief, and financial support for Northern Nevada families with children battling catastrophic illnesses. Learn more about Give Hope and get involved at https://givehopenv.org/

Journal of Clinical Oncology (JCO) Podcast
Intensive Caring: Reminding Patients They Matter

Journal of Clinical Oncology (JCO) Podcast

Play Episode Listen Later Apr 27, 2023 17:25


Dr. Shannon Westin and her guest, Dr. Harvey Max Chochinov, discuss his article "Intensive Caring: Reminding Patients They Matter." TRANSCRIPT The guest on this podcast episode has no disclosures to declare. Dr. Shannon Westin: Hello, everyone, and thank you so much for joining us for another JCO After Hours podcast. This is the podcast that gets in depth in manuscripts published in the Journal of Clinical Oncology. I'm your host, Shannon Westin, GI oncologist by trade and honored to serve as the Social Media Editor for the JCO.  And today we're going to be discussing a really exciting paper in the Comments and Controversies section called “Intensive Caring: Reminding Patients They Matter.” This has been recently published, and I'm so excited to have the author of this paper join us today, Dr. Harvey Max Chochinov, who is a distinguished professor in the Department of Psychiatry in the University of Manitoba, senior scientist with Cancer Care Manitoba Research Institute, and the cofounder of Canadian Virtual Hospice.   Welcome. So great to have you today.  Dr. Harvey Max Chochinov: Thanks, Shannon. Dr. Shannon Westin: And please note neither of us have any conflicts of interest, so we'll just get right started. So first, I just wanted to explore the title of your paper, “Intensive Caring.” Can you describe a bit about what that means? Dr. Harvey Max Chochinov: Well, we know that in medicine there are occasions when patients find themselves in such medical dire straits that they require intensive care. They've reached the stage where they certainly can no longer help themselves, and they require this kind of intensive approach that medicine is capable of offering. But intensive caring is meant to acknowledge that there are times when patients can be in such dire emotional straits that we need a way of being able to address that degree of abject suffering. So the idea of intensive caring was to try and provide language to describe that approach and, within the paper, as we're going to discuss, also to describe the ways in which we can actually deliver that kind of caring. Dr. Shannon Westin: Can you tell me a little bit about kind of when and where your inspiration for this work arose? Dr. Harvey Max Chochinov: The inspiration actually came from Dame Cicely Saunders. Dame Saunders was the founder of the modern hospice movement. There's a famous quote or adage that she said: “You matter because you are you, and you matter to the last moment of your life.” And this has really become kind of a central philosophical tenet of palliative care. But yet it struck me that although it describes this philosophical approach, implicit is also perhaps a clinical approach which says how do we, in fact, show patients—how do we demonstrate to patients or practice medicine in a way that actually affirms that patients matter? So that's where the title came from: “Intensive Caring: Reminding Patients They Matter.” Dr. Shannon Westin: There are so many pieces to this. I was so struck by what you said about these emotional dire straits. That's the best way I've ever heard it described. I feel like one of the major areas is that loss of hope and that feeling that you don't matter anymore. So what can we do? How do we, as practitioners, act and intervene to change that feeling? Dr. Harvey Max Chochinov: That's a wonderful question. The paradigm of contemporary medicine is we examine, we diagnose, and we fix. And yet, when it comes to addressing many elements of human suffering, it doesn't lend itself well to that paradigm because, of course, we know that there are things that are beyond the realm of fixing. So what we need, then, is to understand a way of approaching patient care where fix really is beyond our reach. How do we do that? It's by understanding that by being with the patient, by things like non-abandonment, all of these things are ways of maintaining patient engagement.  There was a wonderful study a number of years ago by Kelly Trevino in which she looked at the associations between suicidality and the intensity and the quality of the connectedness with the medical oncologist. And it turns out that that was the single most predictive factor regarding suicidality over psychological interventions or over psychotropic medication. So the way in which we start to address this kind of abject suffering, maintaining hope, is to understand that and acknowledge that there are things that we may not be capable of fixing. But the provision of intensive caring—and, again, the elements of intensive caring that I described in the article—give us ways of being able to be with patients that don't require fixing but require presence, require involvement, require ongoing commitment to the well-being of that individual.  Dr. Shannon Westin: This is a perfect segue because I was struck by that tenet of non-abandonment, you know, really committing to ongoing care. I wonder about this because we do have patients that transition to hospice, and often, in our group, they'll have an entirely new care team. And that's just part of that intensive caring that the hospice group provides. But I guess, in seeing it in these terms, I'm feeling a little bit like that may not be the ideal way for that transition to happen. So any thoughts on how we kind of combat that? Or how can we work together with hospice so that the patient feels still supported but still gets that hospice care that they so desperately need? Dr. Harvey Max Chochinov: Oh, for sure. Well, I mean, listen, we know that transferring of care is a technical task that can be accomplished by a single stroke of our keyboard on our computer. We transfer care. But there's nothing technical about the issue of caring, connectedness. And so it's unrealistic, and I don't think patients expect that all expertise resides in the hands of one individual or one team. But the reality is that when we've been looking after somebody for days, weeks, months, even years and they now have to transition to other care providers, although care can be transferred, I think there is still this human expectation of ongoing caring.   And caring doesn't necessarily require a great deal of time. It can be accomplished in really nuanced and subtle ways that really, I think, are within our grasp. Picking up a telephone, dropping by for a visit, putting a note in the mail simply to acknowledge that “I understand you're in hospice. Just want you to know that you've been on my mind. Hope things are going as well as they can for you and your family.” That demonstrates continued caring. It doesn't raise expectation that I, your medical oncologist who know you very well, am going to now intervene and take over your care. Dr. Shannon Westin: That's perfect. And I'm actually taking notes myself to—have a couple patients that I need to call today. So moving on to some of the other tenets, the Patient Dignity Question was really, I felt like, a revelation for me. It's so simple and so straightforward, and I feel like many of us, myself definitely included, don't feel like there's enough time, right, to dig into the details of every patient, kind of where they are in their process. Do you think this is something that everybody should implement today? Dr. Harvey Max Chochinov: So maybe backing up just for listeners to understand that the Patient Dignity Question asks patients, “What do I need to know about you as a person in order to provide you the best care possible?” We have done studies of the Patient Dignity Question, or PDQ, and there have been multiple studies and multiple translations around the world, probably the largest study being one that came out—Hadler, first author—several thousand patients at Memorial Sloan Kettering who were asked the Patient Dignity Question as part of the regular kind of palliative care consultation. I think the message that I take out of the PDQ research is that personhood should always be on our radar. And the reality is that if we don't understand at least the essence of who that person is, we can give lip service to providing person-centered care and lip service to maintaining dignity and all of those wonderful things that we say in position statements, but none of it will ring true if we don't have personhood on our radar. And it simply means that we need to be mindful of personhood.  I've asked patients, “So what do I need to know about you as a person to take the best care of you possible?” I've had people tell me, “I'm afraid to die alone.” I've had people tell me, “I am the victim of childhood sexual abuse.” I've had people tell me, “I'm a survivor of the residential school system.” One man said “I'm a former department head of medicine.” In fact, he was just a lovely man. He said when he was being treated for his cancer, he wanted to hang a sign on his bedpost that said, “PIP, Previously Important Person.” But what it says to me is that if we fail to acknowledge personhood, then essentially we're operating in the dark. When you have that kind of information about personhood, it just changes the way you see and experience that person, which makes for better patient care. Families are more satisfied. There's less discordance when it comes to goals of care, less likelihood of litigation because the reason that most people litigate is not because of medical misadventure. It's because they don't feel like they were treated like a person. They somehow feel like that was not acknowledged.   The other interesting piece of data out of the PDQ research is that when clinicians acknowledge personhood, they also report greater job satisfaction. So the reality is—and we know that one of the signs of burnout is emotional disengagement. So what our research has found is that if you give clinicians a way of at least maintaining some emotional engagement by finding out who this person is, not only are patients and families happier, but healthcare providers report greater satisfaction in the work they do. So the short answer is “Yes, I think we should be putting personhood on our clinical radar and finding ways that are feasible of making that happen.”  Dr. Shannon Westin: There's so many interesting tenets in this article and so many parts to the intensive caring. Some do seem to be elements of palliative care practice as well. So how would you say this is different or complementary?  Dr. Harvey Max Chochinov: I'd say indeed you're correct. I mean, some of the elements are probably ones that people in palliative care would recognize. And I don't necessarily think that that's a criticism or necessarily a bad thing. If some elements of intensive caring are accused of being old wine in a new bottle, a new bottle is something that can be very attractive. And if this can bring people back to understanding the human side of health care, well and good. I suppose what is unique about intensive caring are the constellation of elements that are described in the article—and all of the elements, by the way, are empirically based. So the article does lay out various elements of intensive caring and points out the empirical basis of each of those elements.   I think maybe the other thing that's unique about intensive caring is it begins to provide us a language for ways of being able to approach patients who are in these circumstances. Usually, in the face of this kind of abject suffering, our temptation is to feel the need to withdraw, maybe feelings of impotence, maybe feelings of failure. So intensive caring addresses all of those head-on by saying here is a way that you can effectively be with your patients, that you can mitigate their suffering, without feeling that your mandate is to examine, diagnose, and fix. It is a different paradigm, which says you can be present with and provide comfort to. Dr. Shannon Westin: Great. Now, what about therapeutic humility? Can you speak of it like that? I think many of us come into medicine because we like fixing problems. So how does this concept turn the paradigm on its head? You kind of already talked about it a little bit, but I think it's important to mention specifically.  Dr. Harvey Max Chochinov: I think anybody who's been practicing medicine for any period of time has had the experience of confronting things that don't lend themselves well to fixing. Let's take the instance of somebody who is near end of life, or even the instance where a patient has died, you're standing outside of their room, and the family is still there. You have some choices. You can either withdraw, just say, “There's nothing I can do; I've got other things that are more pressing,” or you can go into that room. Now, when you go into that room, you need to be able to put on the shelf any idea that you have the right words that are going to fix what ails this now bereft family.  But I think wise and seasoned clinicians—and I would put to you, see, clinicians who have therapeutic humility would say you go into the room. Why? Because being there, just being present with, acknowledging the loss—and it's not about what you say. Again, if you feel like you have to wait till you have the right words, you never will go in there. But if you just go in empty-handed and allow yourself to be in the presence of that kind of suffering, what any clinician who does that will say is it's of critical importance. It matters. It makes a difference. And so that is one example of therapeutic humility. And again, there are others because there is so much that we deal with. For those of us who deal with patients with chronic illness or incurable illness, the fact is that if you're not humble, you're going to find yourself perpetually feeling like you are failing, like you are not meeting patients' expectations. What patients expect is not that you can fix what's not fixable. They expect you to be involved. They expect you to care. You will be there for them in times that are tough. Those are elements of intensive caring that are worth taking forward into practice. Dr. Shannon Westin: Well, this has been so educational. I feel like I could talk with you for another hour. But why don't we end by just speaking about the next steps for this work, and how can we make everyone aware aside from publishing in the JCO and putting out this podcast? What else can we do? Dr. Harvey Max Chochinov: Well, hopefully, the approach gives people both the language and the ways in which we can start to implement this in practice. I would hope that it kind of catches or takes hold in medical curricula, but not only in medicine but really in any setting where individuals are being trained who have access to patients. This is not just about doctors. This is about anyone and everyone who has patient contact because the reality is that irrespective of whether you're the medical receptionist or the person making the first incision, you have the ability to either affirm or disaffirm the personhood of the individual that you're in the presence of. That's both a responsibility and, as well, an opportunity. So hopefully, dissemination of this work spreads word that this is an opportunity that we can take hold of, hopefully for the betterment of patients and families and healthcare providers themselves.  Dr. Shannon Westin: Great. Well, thank you so much. You've been such an inspiration. I can't wait to start utilizing these in my clinic just tomorrow. So I really appreciate you, and I know all our listeners do as well.   Listeners, we appreciate you. Thank you so much for tuning into JCO After Hours. Again, we were discussing the Comments and Controversies article “Intensive Caring: Reminding Patients That They Matter.” I hope you enjoyed it. Please do check out the website and check out any other podcasts that are ongoing and let me know what you think. Have a great day.  The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    

Yeni Şafak Podcast
Hayrettin Karaman - Uyuşturucu Kaçakçılığı ve Ticaretinin Cezası

Yeni Şafak Podcast

Play Episode Listen Later Nov 20, 2022 5:02


Soru …Kur'an'da uyuşturucu maddelerin haram ve yasak olduğuna dair bir ayet yok, hadislerde de yok; şu halde neye dayanarak uyuşturucu haramdır diyorsunuz ve bunun ticaretini yapanlara ceza verilmesini meşru görüyorsunuz? Cevap Böyle bir soruyu aklı ve vicdanı yerinde olan bir kimsenin sormasını mümkün görmüyorum, ama yine de bilgi tazelemek için bir cevap yazmayı uygun gördüm. Uyuşturucu maddeleri, tıbbi zaruretler dışında kullanmak üzere üretmek, alıp satmak, bulundurmak hemen bütün ülkelerde yasaklanmıştır. Uyuşturucu alışkanlığı, insanı insanlığından çıkaran, onu uyuşturucuya esir eden, bağımlı hale getiren bir iptiladır. Bu alışkanlıkla mücadele etmek bütün insanların başta gelen ödevleri olmalıdır. İnsanlara bu ölçüde zarar verme pahasına para kazanmak bir insanlık suçudur. Bu suçun da kendi ağırlığına uygun bir cezası olmalıdır. Hangi cezanın uygun olduğu ve ceza yanında ne gibi eğitici tedbirlerin alınması gerektiği konusu yıllardır tartışılmakta, çeşitli ülkelerde farklı cezalar ve tedbirler uygulanmaktadır. Kur'an-ı Kerim'in nazil olduğu çağda, özellikle Arap yarımadası ve yakın çevresinde insanlar uyuşturucuyu bilmiyorlar, keyif verici ve sarhoş edici olmak üzere alkollü içki ve bilhassa şarap kullanıyorlardı. Kur'an ve Sünnet insanın hayatını, sağlığını, aklını tehdit eden, bunlar için tehlike teşkil eden nesnelerin vücuda alınmasını yasakladığı gibi malın korunmasını da emretmiş, boş, faydasız, zararlı sarf mânâsında israfı şiddetle kınamıştır. Uyuşturucu kullanımı da bu genel yasaklama çerçevesine girmektedir; çünkü kullanan kimselerin akıl, ruh ve beden sağlığını bozmakta, kamu düzenine zarar vermekte, yeni nesilleri dejenere etmekte ve malın boş yere ve zararlı sonuçlar verecek şekilde harcanmasına sebep olmaktadır. Şu halde İslâm'a göre de uyuşturucu kullanımı, alım-satımı, üretimi, bulundurulması mutlaka önlenmelidir. Önleyici tedbir olarak eğitim başta gelmekle beraber kötü niyetli, merhametsiz, hırslı, insanlık düşmanı üretici ve kaçakçılara da caydırıcı cezalar uygulanmalıdır. İslâm'da (şeriatta) cezalar hadler, kısas ve tazîr şeklinde üç nevidir. Hadler suç ve ceza olarak ayetler ve hadislerle belirlenmiştir; bunların içinde uyuşturucu ile ilgili bir suç yoktur. Kısas, öldürme ve yaralama suçlarında uygulanmaktadır. Bu iki nevi suçun dışında kalan suçlar tazîr çerçevesine girmekte, takdiri, tarifi ve cezası ümmetin temsilcilerine (yöneticilere, ulü'l-emre) bırakılmış bulunmaktadır. Temsilciler meclisi konuyu görüşecek, toplu içtihat yoluyla bir çözüm paketi getirecektir. Bunun içinde ceza da bulunacak, bu ceza içtihat yoluyla şeriata dâhil edilecektir. İçtihat yoluyla şeriata dâhil edilen diğer hükümler gibi bunda da ümmetin ihtilaf etmesi, farklı cezaların teklif edilmesi tabiidir. Bu durumda devlet başkanı ve temsilciler, kabul edilen kanun çıkarma usulüne göre hangi cezayı kanunlaştırmaya karar vermişlerse ülkede o ceza uygulanacak ve bu ceza şeriata (İslâm) uygun görülecektir. Bu cezanın ölüm (idam) olması da mümkün ve caizdir.

Q-Media's On Demand
Tim Hadler of Gumi Camp USA

Q-Media's On Demand

Play Episode Listen Later Oct 26, 2022 8:00


Tim Hadler of Gumi Camp USA --- Send in a voice message: https://anchor.fm/wcmp-news/message

In the Zone
Letting go of the Olympic dream and transforming stuck emotions with Beek Hadler

In the Zone

Play Episode Listen Later Oct 14, 2022 148:39


In this episode I have an interesting conversation with Beek Hadler who I met in Chamonix Beware throughout the episode the topic of an eating disorder is touched upon. Contact Beek via email: beekhadler@web.de or Instagram: https://www.instagram.com/beek.hadler/ Reach out on Linkedin: @Kobe Blondeel or Instagram: @InTheZone.

The Digital Agency Show | Helping Agency Owners Transform Their Business Mindset to Increase Prices, Work Less, and Grow Prof

Richard Handler is the CEO of alan. Agency, one of the fastest growing B2B Marketing agencies in Europe. He's the author of Markeing. The Bottom Line and the host of the podcast, B2B Marketing: The Provocative Truth. Richard is passionate about bridging the gap between Sales and Marketing and wants to challenge B2B marketers to think more creatively.

Agency Dealmasters podcast
Richard Hadler discusses B2B marketing: The bottom line

Agency Dealmasters podcast

Play Episode Listen Later May 17, 2022 39:17


Richard Hadler is CEO of alan. and author of the book 'Marketing: The Bottom Line'. alan. are a full-service B2B marketing agency for Tech, FS + Professional Services. They are reimagining the modern-day B2B marketing agency. alan. is the agency that finds ingenious solutions to complex B2B marketing problems. We talk about:

Recovery Recharged with Ellen Stewart: The Pushy Broad From The Bronx®

What is California Sober and will it work for you? We talk Pros and Cons with Clinical expert, Nelson Hadler, LCSW.

Transformation Talk Radio
California Sober with Nelson Hadler

Transformation Talk Radio

Play Episode Listen Later Apr 13, 2022 55:29


What is California Sober and will it work for you? We talk Pros and Cons with Clinical expert, Nelson Hadler, LCSW.

Q-Media's On Demand
A Conversation with Musician Tim Hadler (03.30.22)

Q-Media's On Demand

Play Episode Listen Later Mar 30, 2022 17:41


A Conversation with Musician Tim Hadler (03.30.22) --- Send in a voice message: https://anchor.fm/wcmp-news/message

My Point Of View
WOMEN'S MARCH I Sexism In Pop Culture: Britney Spears, Taylor Swift, Janet Jackson and more with Madison Hadler from Loud Mouth Podcast

My Point Of View

Play Episode Listen Later Mar 21, 2022 54:06


Today's episode is the third one from Women's March, 2022 edition.  As the name suggest, for the month of March, since the 8th is International Women's Day, I'm going to be doing 4 women empowerment and feminism focused episodes, bringing different guests from different walks of life, to talk all about their experience with being a woman, feminism & women empowerment.  For this third episode I'm joined by Madison Hadler, host of the Loud Mouth Podcast, a podcast all about being LOUD about activism, our passions, and changing our communities, check out new episodes released every Wednesday! We decided to chat together about sexism and misogyny in pop culture. We talked about:  - Britney Spears' "breakdown" in 2007: how we saw it then and how we see it now, and how it made Britney a real person and why people didn't like that - Actors that have been accused of sexual assault, like Ed Westwick, Ansel Elgort, that are still praised on social media or by awards - Taylor Swift, how she has been demonized as a slut because she dated “too many men”: how and why people started treating her songwriting as something bad, rather than a skill, and how even when she's starting to take back the power and rerecord her songs, people still make it about the people she dated - We touched on at the beginning: Monica Lewinsky's scandal and why was the intern the problem and not the president of the United States and Serena Williams and her “angry black woman” trope Janet Jackson's super bowl nip slip and how people filed complaints about her and she was blacklisted, and how Justin Timberlake went on to build the career he has now - Simone Biles: how taking a break made her get railed by people online, how mental health and her race plays a role in her taking a break, how people would've criticized her anyways and how this show that sexism is still a thing in today's pop culture. Loud Mouth Podcast: https://podcasts.apple.com/us/podcast/loudmouth/id1439949776 Loud Mouth IG: https://www.instagram.com/loudmouthpod/ Follow me: https://www.instagram.com/mypointofview.podcast/  Music: Cheese, prod. by Lukrembo https://soundcloud.com/lukrembo/cheese

Epigenetics Podcast
Epigenome-based Precision Medicine (Eleni Tomazou)

Epigenetics Podcast

Play Episode Listen Later Mar 10, 2022 40:08


In this episode of the Epigenetics Podcast, we caught up with Eleni Tomazou from St. Anna Children's Cancer Research Institute in Vienna to talk about her work on Epigenome-based precision medicine. The Tomazou lab studies Ewing sarcoma and the effects of Epigenetic factors on this disease. Ewing sarcoma is a type of cancer that affects bone and soft tissue of children and young adults, with a peak incidence at the age of 15. Ewing sarcoma is among the pediatric cancer types with the lowest survival rates and the development of novel therapies was obstructed by the limited understanding of the mechanisms behind the disease. Work done in Eleni Tomazou's group identified an epigenetic signature of Ewing sarcoma which, ultimately, lead to the possibility to diagnose Ewing sarcoma from liquid biopsies. The team is now looking to find actionable targets like enhancers to develop therapies, finding biomarkers to enable disease monitoring, and to further characterize these tumors to decipher intra-tumor epigenetic heterogeneity and characterize the developmental stage of the cell of origin.   References Tomazou, E. M., Sheffield, N. C., Schmidl, C., Schuster, M., Schönegger, A., Datlinger, P., Kubicek, S., Bock, C., & Kovar, H. (2015). Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1. Cell Reports, 10(7), 1082–1095. https://doi.org/10.1016/j.celrep.2015.01.042 Sheffield, N. C., Pierron, G., Klughammer, J., Datlinger, P., Schönegger, A., Schuster, M., Hadler, J., Surdez, D., Guillemot, D., Lapouble, E., Freneaux, P., Champigneulle, J., Bouvier, R., Walder, D., Ambros, I. M., Hutter, C., Sorz, E., Amaral, A. T., de Álava, E., … Tomazou, E. M. (2017). DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma. Nature Medicine, 23(3), 386–395. https://doi.org/10.1038/nm.4273 Terlecki-Zaniewicz, S., Humer, T., Eder, T., Schmoellerl, J., Heyes, E., Manhart, G., Kuchynka, N., Parapatics, K., Liberante, F. G., Müller, A. C., Tomazou, E. M., & Grebien, F. (2021). Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression. Nature Structural & Molecular Biology, 28(2), 190–201. https://doi.org/10.1038/s41594-020-00550-w Peneder, P., Stütz, A. M., Surdez, D., Krumbholz, M., Semper, S., Chicard, M., Sheffield, N. C., Pierron, G., Lapouble, E., Tötzl, M., Ergüner, B., Barreca, D., Rendeiro, A. F., Agaimy, A., Boztug, H., Engstler, G., Dworzak, M., Bernkopf, M., Taschner-Mandl, S., … Tomazou, E. M. (2021). Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden. Nature Communications, 12(1), 3230. https://doi.org/10.1038/s41467-021-23445-w   Related Episodes Epigenomics (Henk Stunnenberg) Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) Cancer and Epigenetics (David Jones)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

JV Adulting
Mental Ruts with Brandon Hadler

JV Adulting

Play Episode Listen Later Nov 22, 2021 45:18


This week we are joined by Brandon Hadler. Brandon shares his personal story about physical trauma which then led to him suffering mental trauma. We dive into different ways to get yourself out of a mental rut, recommendations he has found through his research and other best practices.

Unforbidden Truth
Interview with Ohio offender Tyler Hadler

Unforbidden Truth

Play Episode Listen Later Jul 20, 2021 15:29


On this weeks episode, Andrew speaks with Ohio inmate, Tyler Hadler. Tyler Hadler, 20 years old at the time of his crime, struck Patrick Smith with his car and pinned him against a garage on September 23, 2008. Patrick died of his injuries in a nearby hospital, hours later. Tyler was charged and convicted of voluntary manslaughter and attempted murder, receiving a 14 year prison sentence.Apple Podcasts: https://podcasts.apple.com/us/podcast/unforbidden-truth/id1531427832Patreon: https://www.patreon.com/UnforbiddentruthSpotify: https://open.spotify.com/show/2pR7TgAdNX1rdvIIadm6mxYoutube: https://www.youtube.com/channel/UCUePWe5xZsertnRvejzTQlg

World Book Club
Jane Harper

World Book Club

Play Episode Listen Later Jul 7, 2021 49:28


World Book Club this month talks to the world-renowned Australian author Jane Harper at her home in Melbourne, Australia, about her internationally garlanded thriller, The Dry. Amid the worst drought to ravage Australia in a century, tensions in a small town community become unbearable when the Hadler family are found brutally murdered. Everyone thinks Luke Hadler's guilty, committing suicide after slaughtering his wife and son. But policeman Aaron Falk returns to the town of his youth for the funeral of his best friend and is reluctantly drawn into the investigation. As he probes deeper into the killings, secrets from the past bubble to the surface and he questions the truth of his friend's crime. A chilling story set under a sweltering sun dealing with issues of climate change, alcoholism and a community on the brink of breaking down. (Picture: Jane Harper. Photo credit: Katsnapp Photography.)

The Inner Work with Emma Hansen
Inner Drive. Pivoting. Building Confidence with Brandon Hadler

The Inner Work with Emma Hansen

Play Episode Listen Later May 7, 2021 60:12


On today's episode Brandon Hadler shares his journey with us. Everything from taking the leap and pivoting from sales to coding, moving across country, dealing with injuries and starting his own Podcast.  Its a good one! Going Local with B : https://open.spotify.com/show/5pe5nYJMGzPSLhykRhdo9F?si=p45ZAJ27Q3a_Z7aB1zEgZQ My episode with Brandon: https://open.spotify.com/episode/4t2fZtgR19JNXOivVf2WK0?si=0330e6625a1d493b Brandon's Instagram: https://www.instagram.com/brandonhadler/

Logic Over Emotions
Ep:11 Convo's with Professionals (Special Guest Brother Hadler Lab Technician at Columbia University) Motivational Mondays Part 5

Logic Over Emotions

Play Episode Listen Later Mar 15, 2021 47:31


On This Episode i interviewed another brother of mine Hadler. Hadler originally came from Brazil and had to basically grow up faster than other children. Helping his amazing mother and family was always the goal. Through the good and bad times he stayed committed and is on his way to getting his Master Degree. Super proud of my guy who basically is finding ways to make the world a safer environment for us all  Dont Forget to Follow me on my Instagram @Mellvb Mel B

Utility4.0 - The future of energy
#25 mit Tina Hadler & Martin Stötzel (coneva)

Utility4.0 - The future of energy

Play Episode Listen Later Feb 22, 2021 94:59


Diese Podcast-Folge dreht sich rund um die Digitalisierung vor, am und hinter dem Netzanschluss, den wir alle haben, so wir denn Strom heute aus den allgemeinen Netzen ziehen oder aus der eigenen Energieernte in sie einspeisen. Dabei haben sich im Gespräch mit Tina Hadler (Product Manager Energy Communities bei coneva) und Martin Stötzel (Product & Marketing Manager bei coneva) inhaltlich zwei Schwerpunkte entwickelt: - Was bedeutet dieser "Post-EEG-Systemwechsel” für die Endkunden und welche neue Chancen und Optionen ergeben sich für Stadtwerke und andere Energieversorgungsunternehmen? - Wie eine Energy-Buddy-App die Energy-Consumer und zukünftigen -Prosumer dort abholen und begeistern kann, wo sie heute stehen?

Holiday Breakfast
Richard Arnold: Covid-19 continues to cripple US states, vaccine rollout off to messy start

Holiday Breakfast

Play Episode Listen Later Dec 31, 2020 4:36


Terry Beth Hadler was so eager to get a lifesaving COVID-19 vaccination that the 69-year-old piano teacher stood in line overnight in a parking lot with hundreds of other senior citizens.She wouldn't do it again.Hadler said she waited 14 hours and that a brawl nearly erupted before dawn on Tuesday when people cut in line outside the library in Bonita Springs, Florida, where officials were offering shots on a first-come, first-served basis to those 65 or older.“I'm afraid that the event was a super-spreader," she said. “I was petrified.”The race to vaccinate millions of Americans is off to a slower, messier start than public health officials and leaders of the Trump administration's Operation Warp Speed had expected.Overworked, underfunded state public health departments are scrambling to patch together plans for administering vaccines. Counties and hospitals have taken different approaches, leading to long lines, confusion, frustration and jammed phone lines. A multitude of logistical concerns have complicated the process of trying to beat back the scourge that has killed over 340,000 Americans.Florida Gov. Ron DeSantis is asking for patience, noting the vaccine supply is limited.“It may not be today for everyone, may not be next week. But over the next many weeks, as long as we continue getting the supply, you're going to have the opportunity to get this,” he said Wednesday.Florida has placed a priority on residents 65 and over to receive the vaccine once medical workers and long-term care residents and staff get the shots. The decision bucks a suggestion from the Centers for Disease Control and Prevention to place a priority on people 75 and older and essential workers like teachers and first responders as the next to get vaccinated.Dr. Ashish Jha, a health policy researcher and dean of the Brown University School of Public Health, said the main problem is that states are not getting adequate financial or technical support from the federal government. Jha said the Trump administration, principally the Department of Health and Human Services, has set states up to fail.“There's a lot states still need to do," he said, "but you need a much more active role from the federal government than what they have been willing to do. They've largely said to states, ‘This is your responsibility. Figure it out.'”Lags in reporting vaccination numbers explain in part why many states aren't meeting their year-end goals, but officials blame logistical and financial hurdles for the slow pace.Many states lack the money to hire personnel, pay for overtime or reach out to the public. The equipment required to keep the vaccines cold complicates their distribution. Also, providers need to track vaccinations so they have enough to dispense the required second doses 21 days after the first.Dr. James McCarthy, chief physician executive at Memorial Hermann in Houston, said the hospital system has administered about half of the roughly 30,000 doses that it has received since Dec. 15.The system had to create a plan from scratch. Among other things, administrators had to ensure that everyone in the vaccination areas could socially distance, and they had to build in a 15-minute observation period for each patient so that recipients could be watched for any side effects.“We can't just hand it out like candy,” McCarthy said.Pasadena, California, is vaccinating its firefighters in groups of 50 after their two-day shifts are over so they can recuperate during their four days off. “We don't want the majority of our workforce — if they do experience side effects — to be out all at the same time,” city spokeswoman Lisa Derderian said.In South Carolina, state lawmakers are questioning why the state has administered just 35,158 of the 112,125 Pfizer doses it had received by Wednesday. State Sen. Marlon Kimpson said officials told him that some front-line health care workers are declining to be vaccinated, while others are on vacation.Lin Hum...

Alternative Talk- 1150AM KKNW
TTR Network - 07/13/20 - Ellen Stewart - Nelson Hadler - Hour 2

Alternative Talk- 1150AM KKNW

Play Episode Listen Later Jul 13, 2020 55:34


Recovery Recharged with Ellen Stewart: Pushy Broad From The Bronx®: Addiction and Dual Diagnosis

Dr. Pat Show
TTR Network - Ellen Stewart - Nelson Hadler

Dr. Pat Show

Play Episode Listen Later Jul 13, 2020 55:26


Recovery Recharged with Ellen Stewart: Pushy Broad From The Bronx®: Addiction and Dual Diagnosis

Zucker im Ohr
#1 - Der Gedanke als Teebeutel (mit Colin Hadler)

Zucker im Ohr

Play Episode Listen Later Feb 4, 2020 39:57


In diesem Podcast werden Gedanken weitergedacht, Gedanken über's Lesen vor sieben Jahren, Tee und Bossabteilungen des Lebens. || Instagram Colin: instagram.com/colinhadler/ || Twitter: twitter.com/ohrzckr || Instagram: instagram.com/ohrzckr/  

Andrey Egorov
Sweetsetsation© @ Andrey Egorov @ ТОП-100 (2017) 10-ка лучших треков 2017 года

Andrey Egorov

Play Episode Listen Later Dec 29, 2017 30:38


Друзья!))) Настало время подвести итоги уходящего 2017 года.Этот год был очень боогат на новинки) До нового года остаеться буквально 2 дня, и каждый из нас ждет от Нового года,чего-то нового,не обычного,чуда.Все готовятся к встречи 2018 года. Каждый год по традиции,все DJ  представляют свой отчет ,свой ТОП треки которые на их взгляд самые самые. Я уже какой раз не остаюсь в стороне и поддерживаю данную традицию.Всем приятного прослушивая. Хорошего настроения)ТОП-100 Уходящего 2017 года  by Andrey Egorov Let's GO!p.s.В ТОП-100 (2017) вошел самый сок клубных треков за весь 2017 год. Всех С Наступающим Новым 2018 годом!!! Пусть сбудуться все ваши мечты,желания. в каждом доме будет счастье ,успех и самое главное здоровье. И что-бы у каждого из нас звучала только самая лучшая,крутая музыка а какие треки будут в 2018 году и каким будет следующий топ-100 в 2018 году,мы узнаем в конце следующего года)))с уважением,Andrey Egorov(с.) Sweetsetsation© by Andrey Egorov @ Итоговый ТОР-100 2017 года (10- ка лучших треков) 001.Charlie Ray ft. Dirty Ducks - Nova (Extended Mix) 002.BL3R vs. Jaxx & Vega – Pulsar 003.Arilena Ara - Nentori (Denis First Remix) 004.Shakecraft feat. Elektra - Patchy (Denis First Remix) 005.Paul Green - Paul Green – Beacon 006.Switch Off Le Shuuk — All in My Head (Extended Mix) 007.Bobby Rock - My Feelings (Original Mix) 008.Jose De Mara, Steve Powers, Lil'Eddie - Forever Mine (Dirty Ducks Remix) 009.Zheno & Macbass vs. Hadler feat. Katty McGrew - The Evolution (Original Mix) 010.Mike Candys — I Keep Going (Radio Edit)

dj andrey jose de mara charlie ray zheno hadler steve powers bl3r shakecraft macbass katty mcgrew the evolution original mix
Pain Science and Sensibility
Episode 30: I am a Placebo: An Interview With Dr. Nortin Hadler, MD

Pain Science and Sensibility

Play Episode Listen Later Dec 28, 2017 56:48


Our guest in this episode is Dr. Nortin Hadler, a rheumatologist and professor of medicine at the University of North Carolina in Chapel Hill, who has spent decades right in the middle of several health care debates. Dr. Hadler, or as Sandy likes to call him "Quote Machine," spent an hour with us reflecting on a range of topics. What is medicalization and why is so important? What predicts poor health outcomes related to regional pain disorders most robustly? What is the difference between a treatment act and a treatment encounter? Why do people shop in the placebo aisle of the grocery store? How is a well intentioned provider to proceed with care? All of this and much more in this episode. Links to his books via Amazon:           Music by Kevin MacLeod - incompetech.com: Intro - Brandenburg No4 and Meatball Parade Close - Meatball Parade

Andrey Egorov
Andrey Egorov @ Sweetsetsation mix Выпуск #069(14.07.2017) (promodj.com)

Andrey Egorov

Play Episode Listen Later Jul 14, 2017 56:43


[СВЕЖАК] 14.07.2017 @ Sweetsetsation Долгожданный выход мощного ,жаркого выпуска Sweetsetsation mix #069!!! Друзья,представляю вам новый,горячий выпуск Sweetsetsation #069. Выпуск вошли только самые жаркие лучшие клубные EDM треки,которые расскачают тебя по максимуму. Внимание микс заряжен позитивом и энергией Sweetsetsation Come on!Качнем по максимуму эту пятницу!!!)))еее Andrey Egorov @ Sweetsetsation mix Выпуск #069(14.07.2017) 001 - Nighthawk (Extended Mix) - Row Rocka 002 - Lo Air - Day & Night (Denis First Remix) 003 - Hippo - Chocolate Puma & Moksi 004 - Kokab - Got U (Ready Or Not) (Amice Remix) 005 - Wasted (DJ Vega Remix Edit) - Nicco & Jai Matt vs. Erick Ness 006 - Crossroads (John Dahlback Extended Remix) - Navarra & Nicky Romero 007 - Heard Right (Extended Mix) - J-Trick X Tom Budin 008 - Pulsar - BL3R vs. Jaxx & Vega 009 - Festival Of Lights - KSHMR & Maurice West 010 - Portugal The Man - Feel It Still (Denis First Remix) 011 - The Evolution (Original Mix) - Zheno & Macbass vs. Hadler feat. Katty McGrew 012 - Momentum (Original Mix) - Don Diablo 013 - DJ Kuba & Neitan - Bring the House Original Mix - 014 - David Guetta feat Justin Bieber - 2U (DJ Ramirez & Mike Temoff Remix) 015 - Boomerang (Extended Mix) - Hirshee & Cielo feat. Chris Reeder 016 - Bakermat feat Kiesza - Dont Want You Back (Lavrushkin Remix) 017 - LLP - Rio - 018 - Feel Good (Brooks Radio Edit) (feat. Daya) - Illenium & Gryffin 019 - Nova (Extended Mix) - Dirty Ducks & Charlie Ray 020 - Save Me (Midi Culture Extended Remix) - Mahmut Orhan feat. Eneli

Club Banditz presents Red Alert Radioshow
Club Banditz Presents ‘Red Alert Radioshow powered by Monster’ Episode #194

Club Banditz presents Red Alert Radioshow

Play Episode Listen Later Apr 18, 2017


Tracklist: 1 - Kygo & Selena Gomez - It Ain't Me (Tiësto's AFTR HRS Remix) 2 - eSQUIRE feat. Leanne Brown - Blackwater (eSQUIRE Late Night Extended Mix) 3 - Cedric Gervais feat. Digital Farm Animals & Dallas Austin - Touch the Sky (Extended Mix) 4 - Tom Staar, Rob & Jack - Sunshine (Original Mix) #Fresh of the Week: 5 - Federico Costantini - Break The Wall Feat B-Law 6 - Promise Land - Geyser (Extended) 7 - Corey James - Bring It (Extended Mix) 8 - JP Candela & Robbie Rivera - Morenita (Simon Kidzoo & Mike Mendo Extended Remix) 9 - D.O.D - Satisfy (Original Mix) 10 - Tom Swoon & Teamworx - Atom (Extended Mix) #Mashup of the Week: 11 - Bowser vs My Way vs Phatt Bass (Hardwell Mashup) 12 - The Chainsmokers & Coldplay - Something Just Like This (JAKKO Remix) 13 - Marshmello - Alone (ANGEMI Remix) 14 - Curbi x Mesto - BRUH (Extended Mix) 15 - Zheno & Macbass vs. Hadler feat. Katty McGrew - The Evolution (Original Mix) 16 - Jorge Bastoz - What (Original Mix) 17 - W&W - Put Em Up (Extended Mix) For more info check: www.facebook.com/clubbanditz www.twitter.com/clubbanditz www.instagram.com/clubbanditz Snapchat: clubbanditz

Essential Selection
Essential Selection #117 (Special Miami Music Week)

Essential Selection

Play Episode Listen Later Mar 20, 2017 60:02


Essential Selection #117 Comment and share it using #ES117 Tracklist 20/03/2017: 1)HI-LO - The Answer (Oliver Heldens Edit) 2)Koala Street - PRC (Original Mix) 3)JaySounds - The Vibe (Original Mix) 4)Sagan & Gregori Hawk - Bounce (Extended Mix) 5)Fox Banger - Loop Machine (Original Mix) 6)Anderblast - Theory (Original Mix) 7)Tiesto - Flight 643 (ANG & KEVU Bootleg) 8)Will Sparks x Orkestrated - Crank It Loud (Garabatto Remix) 9)Fais & Afrojack - Used To Have It All (Gerald Le Funk Remix) 10)Jaycen A'mour - Dirty Sexy Freaky (Original Mix) 11)Jauz - Claim To Be (Original Mix) 12)R3SPAWN & Kroshwell - Warfare (Extended Mix) 13)Vigel & Ale Q feat. Jack Wilby - Feel So Alive (Extended Mix) 14)Zheno & Macbass vs Hadler feat. Katty McGrew - The Evolution (Original Mix) 15)KIIDA vs. J-Trick - Lose It (Extended Mix) 16)Rasalifers X Dark Drake - Low5 (Original Mix) 17)Karmatek - Think About It (Original Mix) 18)Kyle Walker - Hold Up (Original Mix) Follow me on social networks: Hearthis: hearthis.at/eddytofficial Soundcloud: soundcloud.com/eddytofficial Facebook: facebook.com/eddytdj Twitter: twitter.com/EddyTDeeJay Youtube: youtube.com/user/buciafola Instagram: ww.instagram.com/eddy_t_official Bimbomix Records: soundcloud.com/bimbomixrecords

essential selection will sparks hearthis miami music week kiida tiesto flight hadler hi lo the answer oliver heldens edit vigel ale q jack wilby feel so alive extended mix katty mcgrew the evolution original mix
Club Banditz presents Red Alert Radioshow
Club Banditz Presents ‘Red Alert Radioshow powered by Monster’ Episode #189

Club Banditz presents Red Alert Radioshow

Play Episode Listen Later Mar 14, 2017


Tracklist: 1 - Calvin Harris ft. Frank Ocean & Migos - Slide (Pink Panda Remix) 2 - CID feat. Conrad Sewell - Secrets (Kaskade Remix) 3 - Alan Walker - Alone (Lost Frequencies Remix) 4 - Ferreck Dawn & AXRG - Saga (Extended Mix) 5 - Yves V - Find Your Soul (Original Mix) #Fresh of the Week: 6 - TwoWorldsApart & Tom Bourra feat. Max Landry - Make It Home (Original Mix) 7 - Tryde & Krytek - Sao Paulo (Original Mix) 8 - LENNYMENDY - Konsha (Original Mix) 9 - Taurian - Hathor (Original Mix) 10 - Dannic - Fonk It Up (Original Mix) 11 - MOTi - Pull Up (Original Mix) #Mashup of the Week: 12 - The Chainsmokers & Coldplay - Something Just Like This (Marane Bootleg) 13 - Max Vangeli & Databoy - Top Of My Lungs (Promise Land Extended Remix) 14 - Moska x David Nova - ThunderBolt (Original Mix) 15 - Teamworx - Around the world (Original Mix) 16 - Zheno & Macbass vs Hadler feat. Katty McGrew - The Evolution (Original Mix) For more info check: www.facebook.com/clubbanditz www.twitter.com/clubbanditz www.instagram.com/clubbanditz Snapchat: clubbanditz

V Sessions with Yves V
V Sessions 090

V Sessions with Yves V

Play Episode Listen Later Mar 12, 2017 53:58


V Sessions with Yves V - a discovery in electronic music as told by one of the dance scene's most exciting DJ and Producer stars - Yves V! Explore new sounds and the most upfront club beats from Belgium's number 55 DJ in the World according to the official Top 100 DJ Poll. V Sessions presented to you each and every week by Yves V. 01. Watermät - Won't Stop (Vocal Mix) 02. Benny Benassi X Lush & Simon - We Light Forever Up (feat. Frederick) 03. Stadiumx & Muzzaik - Last Night A D.J. Saved My Life (Original Mix) 04. UKato & Wanden - Vitality(Original Mix) 05. KSHMR & Crossnaders ft. Micky Blue - Back To Me (Original Mix) 06. Yves V - Find Your Soul (VIP MIX) 07. Boy Tedson - Spin Me Round (MAYD Remix) 08. Lekko - So Lonely Ft. Junior Paes 09. CYMAZ & ROBERT ABIGAIL - I Know The Way (Original Mix) 10. Ricardo Reyna - Heart's on Fire (Original Mix) 11. Loreno Mayer, Edyra & Nickobella ft. Enya Angel - Fighting On Our Own (Original Mix) 12. Zheno Macbass vs Hadler feat. Katty McGrew - The Evolution (Original Mix) 13. HI-LO - The Answer (Oliver Heldens Extended Edit) CLASSIC OF THE WEEK 14. Mylo - Drop The Pressure (Club Mix)

North Carolina People 2012-2013 | UNC-TV
NC People | Dr. Norton Hadler, Professor of Medicine and Microbiology/Immunology, UNC School of Medicine

North Carolina People 2012-2013 | UNC-TV

Play Episode Listen Later Jun 21, 2012 26:55


Dr. Hadler is a graduate of Yale College and The Harvard Medical School. He joined the faculty of the University of North Carolina in 1973 and was promoted to Professor of Medicine and Microbiology/Immunology in 1985. He serves as Attending Rheumatologist at the University of North Carolina Hospitals.

North Carolina People 2012-2013 | UNC-TV
NC People | Dr. Norton Hadler, Professor of Medicine and Microbiology/Immunology, UNC School of Medicine

North Carolina People 2012-2013 | UNC-TV

Play Episode Listen Later Jun 21, 2012 26:55


Dr. Hadler is a graduate of Yale College and The Harvard Medical School. He joined the faculty of the University of North Carolina in 1973 and was promoted to Professor of Medicine and Microbiology/Immunology in 1985. He serves as Attending Rheumatologist at the University of North Carolina Hospitals.

Clinician's Roundtable
Too Much Medicine? Thinking Twice Before Treating

Clinician's Roundtable

Play Episode Listen Later Jul 30, 2008


Host: Maurice Pickard, MD Guest: Nortin Hadler, MD Dr. Nortin Hadler, professor of medicine and microbiology/immunology at the University of North Carolina at Chapel Hill, joins host Dr. Maurice Pickard to discusses his book, Worried Sick: A Prescription for Health in an Overtreated America. Dr. Hadler's book examines the reach of medical treatment in America and the degree to which health is determined by socioeconomic factors that are out of a doctor's hands.