Podcasts about breakthroughs

Lisa Nichols shares a powerful lesson on permission, identity, and the unauthorized chatter that talks you out of your dreams. In this raw and personal talk, the Secret teacher explains why the internal journey is the hardest part of any external success, what her speech teacher told her that should have ended her career before it started, and the moment on Oprah she realized she was the destination she'd been chasing. This episode will challenge you to give yourself permission to be successful — in spite of your story.Source: The Secret: Teachers Recorded LiveHosted by Sean CroxtonFollow me on InstagramSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are you truly living your best life, or are you operating under a shell built by past setbacks? In this episode, Kris Krohn is joined by infomercial legend, award-winning host, and pitch master Forbes Riley. Grossing over $2.5 billion in sales throughout her career, Forbes shares her journey from an aspiring actress to a powerhouse motivational speaker and business coach.Kris and Forbes dive deep into the psychology of human potential, debunking the myth that people simply "lack confidence." Instead, they explore how past embarrassments and childhood trauma "squish" our natural confidence and drive us to play small. Learn how to shed these protective behaviors, master the art of self-compliments, and step into authentic personal and business breakthroughs.

The Beyond Earth Show with Ray Trujillo Planetary Alignment, Sacred Self-Love, and the Cosmic Call to Rebalance Your Life A Celestial Opening Beneath God's Vast Cathedral In this episode of The Beyond Earth Show, host Ray Trujillo opens the June 13, 2026 transmission by welcoming listeners into a reflection on planetary alignment, the upcoming super new moon in Gemini, and the energetic strands moving through personal and collective life. He frames the episode around soul family, soul contracts, animals, nature, guardian angels, cosmic frequency, and the love of God within a universe that may appear random but is spiritually interwoven. Ray's tone is devotional, metaphysical, and introspective, inviting listeners to look both upward toward the celestial field and inward toward the sacred movements within themselves. When Venus, Jupiter, and Mercury Light Up the Inner Sky Ray focuses on the visible planetary alignment involving Venus, Jupiter, and Mercury, also referring to a broader planetary parade that some describe as including additional planets. He shares that he recently photographed the alignment and found it astonishing that such a beautiful celestial arrangement could be seen with the naked eye and captured with an ordinary camera. Rather than treating the alignment only as an astronomical event, he asks what it may mean for people's daily lives, including their careers, relationships, health, money, emotional states, and inner sense of direction. Breakthroughs at the Crossroads of Career, Health, and Love Ray explains that he has been witnessing a collective pattern of breakthroughs among people he has helped, especially after periods of anxiety, waiting, uncertainty, or personal crossroads. He connects the alignment to clarity in finances, career, relationships, partnerships, and health concerns. In his view, many people are reaching the “home stretch” of situations that have been unclear or unresolved. The planetary conjunction becomes a symbolic and energetic marker of revelation, helping people see where they truly stand and where movement may finally be possible. Science, Spirit, and the Ancient Habit of Looking Up Ray then reflects on the long human tradition of looking to the heavens for guidance, referencing ancient sages, astronomy, and the story of the wise men looking toward the star connected with Jesus. He says that everything above exists under God's celestial creation, while human beings interpret the stars through belief, personal truth, science, metaphysics, and spirituality. For Ray, these fields do not need to oppose one another. Instead, the sky becomes a place where science, spiritual symbolism, and God's creation converge into one vast, meaningful canopy. The Human Body as Its Own Sacred Alignment Ray draws a parallel between planetary alignment and the alignments within human beings. He speaks of chakras, anatomy, blood, the brain's hemispheres, emotional balance, intellectual life, spiritual devotion, and the internal rotations that shape each person's experience. He asks listeners to consider where they are suffering, what is causing that suffering, what would bring them the most joy, and how they might go about “the Father's business.” In this section, the celestial alignment becomes a mirror for personal realignment, encouraging listeners to ask whether their inner world is balanced, prayerful, and connected to higher will. Venus, Sacred Love, and the Mirror of Self-Worth The episode moves deeply into the meaning of Venus, which Ray associates with love, beauty, relationship, harmony, and the goddess-like image of Aphrodite. He reflects on love as a supernatural power that carries sacredness, innocence, and purity, while also acknowledging that love can have shadow aspects when it becomes excessive, blind, unhealthy, or undisciplined. Ray then turns the conversation toward self-love, asking whether listeners can look in the mirror and sincerely say, “I love you.” He connects this to mirror work, self-worth, the teachings of Louise Hay, and the importance of reconditioning the inner dialogue. Prayer, Water, and the Energetic Imprint of Words Ray discusses the emotional and vibrational power of words, thoughts, and intention. He references Dr. Masaru Emoto's work with water as an example of how emotion and vibration may leave an imprint. Ray says that speaking love, prayer, beautiful music, and sincere affirmation can shape the energy within and around us. He compares mirror work to prayer, explaining that both require focus, sincerity, clarity, and intentionality. Whether a person is praying to God, guardian angels, saints, the Holy Spirit, or focusing through meditation, Ray emphasizes that real transformation requires conscious presence rather than empty repetition. Jupiter's Generosity and the Spiritual Economy of Giving Ray then turns to Jupiter, describing it as expansive, benevolent, prosperous, and connected to karmic patterns. He links Jupiter's influence with generosity, prosperity, love, fortune, career, relationships, and health. A major part of the episode centers on the principle that what people give is what they receive. Ray uses simple examples of neighbors exchanging apples, lemons, oranges, nectarines, strawberries, and almonds to illustrate energetic reciprocity. He emphasizes that giving does not have to mean money; it can include prayers, hope, compliments, compassion, encouragement, and sincere wishes for another person's good. Mercury, Communication, and the Cosmic Window Into the Heart With Mercury, Ray focuses on communication, decision-making, clarity, intellectual processing, and the ability to speak with oneself, God, the universe, and the cosmic kingdom. He says this alignment offers a “cosmic window” into the heart, intellect, and interior life. Through that window, people can ask whether their energy is balanced, where they are giving too much, where they are being drained, and how they can recharge themselves. The Mercury influence becomes a call to communicate wisely, inwardly and outwardly, with honesty, discernment, and spiritual awareness. Gemini's Super New Moon and the Discipline of the Pause Ray prepares listeners for the upcoming super new moon in Gemini, warning that it may bring emotional explosiveness, sudden honesty, impulsivity, or communication shakeups. He does not present this as fear-based, but as a time for temperance, patience, and self-control. He advises listeners to think before speaking, especially if they feel the urge to be brutally honest or direct. Boundaries are important, but Ray cautions that harshness can create regret and require repair later. If something is not urgent, he says, it can wait, because patience is a virtue and not every emotional impulse needs immediate expression. Cord-Cutting, Boundaries, and the Courage to Release What Drains You Ray also speaks to listeners who may be feeling emotionally exhausted, empathically overloaded, or weighed down by the frequency of recent events. He encourages rest, self-care, and time out, especially for caregivers, caretakers, and people whose work or life has become draining. He says this may be an especially meaningful time to examine energetic cords, negative attachments, one-sided relationships, vampiric drains, and situations that no longer contribute to peace, health, or harmony. His advice is to review what serves, what does not serve, what is reciprocal, what is harmful, and whether a person, place, object, or decision truly aligns with one's future. Gratitude as the Light That Magnetizes More Light Near the end, Ray emphasizes gratitude as a life-giving, life-affirming force. He encourages listeners to be grateful not only for blessings, but even for some painful experiences that taught them, strengthened them, or revealed survival. He explains that gratitude opens fields in the brain, heart, body, and spirit, creating a “magic essence” that attracts more auspicious events. By contrast, self-defeating thoughts, regret, anger, and limiting beliefs can magnetize more darkness. Ray compares this to choosing which mirror to look into: the mirror of gratitude, light, and possibility, or the mirror of complaint, despair, and limitation. Becoming the Miracle You Are Waiting For Ray closes by reminding listeners that they deserve to receive, deserve answered prayers, and are themselves part of the miracle they seek. He encourages them to use the alignments and energetics of the celestial field under God's kingdom for their own highest good and for the good of everyone around them. His final message is one of self-affirmation, faith, gratitude, light, and service. He thanks the audience for joining him, blesses them, and says he will return in two weeks.

In this illuminating episode of 5 Minutes of Peace, we explore the transformative concept known as the Power of Eight — inspired by the research of Lynne McTaggart and the applied innovation model of Mark Stinson.Discover how gathering a small group of people with a shared intention (even for just 10 minutes) can shift brainwave patterns, dissolve the sense of separation, and create a powerful state of connection and oneness. Like a beam of focused light, collective intention becomes a force that cuts through distraction and taps into something deeper and universal.The episode also introduces the rebound effect—a profound insight into how directing healing energy toward others activates the body's relaxation and restoration systems. In a beautiful reversal of traditional self-help thinking, we find that helping others may be the most direct path to our own healing and peace.Finally, we explore how this same principle fuels creativity and innovation. By bringing together diverse perspectives in a focused, ego-free space, the “N-of-8” model demonstrates how collective intention can unlock powerful collaboration, accelerate problem-solving, and spark breakthrough ideas.This episode is a gentle reminder: when we shift our focus outward in service and connection, we unlock something extraordinary within ourselves.What You'll Experience in This Episode:A simple explanation of the Power of Eight and how it worksHow group intention can influence brainwaves and emotional statesThe healing benefits of altruism and the “rebound effect”A new perspective on self-help through service to othersHow collective focus enhances creativity and innovationA Moment of Reflection:Where might you invite others into shared intention?What could shift if your focus moved from “me” to “we”?By directing our energy toward the healing and growth of others, we discover a powerful pathway to our own peace, connection, and creative expansion.Connect & Continue the Journey:To learn more about sessions, Reiki training, and community experiences, visit:

Are we witnessing the collapse of the government's 10-year NHS plan, or are we on the brink of a healthcare revolution? Live from the NHS ConfedExpo 2026 in Manchester, former health ministers Steve Brine and James Bethel sit down to analyse a seismic period for health and politics. Following the shocking resignation of Wes Streeting and the appointment of James Murray as Secretary of State, we ask: who is steering the ship, and could an Andy Burnham administration be on the horizon?We also dive into incredible healthcare breakthroughs: the world's first AI-designed vaccine passing human trials at the University of Cambridge, and game-changing precision therapies doubling advanced pancreatic cancer survival rates.Plus, special guests Richard Sloggett (Future Health Research) and Lee-Ann Farrell (J&J) join the pod to discuss social care levies, NHS structural changes, and the reality of innovation on the frontline.

【欢迎订阅】 每天早上5:30，准时更新。 【阅读原文】 标题：Breakthroughs for batteries could soon make them much better Solid-state cells would be faster and safer than today's lithium-ion equivalents正文：Like any champion who spends too long at the top, the lithium-ion battery is stagnating. Over decades as the battery of choice in everything from smartphones to electric cars and drones, its design has been tweaked countless times to improve its energy density and performance. But, some scientists say,those improvements are approaching their theoretical limits. Even the best models are prone to dying out in the cold, rapidly losing capacity or—as is the case for those in household devices—spontaneously catching fire. Meanwhile,demand for batteries has never been greater. By the end of the decade,battery installations could rise by almost 40% globally, and electric vehicles (EVs) are projected to command 30% of car sales in 2026. Worthy challengers are desperately needed. 知识点： champion n. /ˈtʃæmpiən/a person or thing that ranks top and achieves outstanding success. 佼佼者；冠军；顶尖事物e.g. This bakery has long been the champion of local dessert sales. 这家烘焙店一直是本地甜品销量的佼佼者。获取外刊的完整原文以及精讲笔记，请关注微信公众号「早安英文」，回复“外刊”即可。更多有意思的英语干货等着你！ 【节目介绍】 《早安英文-每日外刊精读》，带你精读最新外刊，了解国际最热事件：分析语法结构，拆解长难句，最接地气的翻译，还有重点词汇讲解。 所有选题均来自于《经济学人》《纽约时报》《华尔街日报》《华盛顿邮报》《大西洋月刊》《科学杂志》《国家地理》等国际一线外刊。 【适合谁听】 1、关注时事热点新闻，想要学习最新最潮流英文表达的英文学习者 2、任何想通过地道英文提高听、说、读、写能力的英文学习者 3、想快速掌握表达，有出国学习和旅游计划的英语爱好者 4、参加各类英语考试的应试者（如大学英语四六级、托福雅思、考研等） 【你将获得】 1、超过1000篇外刊精读课程，拓展丰富语言表达和文化背景 2、逐词、逐句精确讲解，系统掌握英语词汇、听力、阅读和语法 3、每期内附学习笔记，包含全文注释、长难句解析、疑难语法点等，帮助扫除阅读障碍。

Summary: In this inspiring message, Ms. G explores the profound relationship between breakdowns and breakthroughs, encouraging us to see difficulties as essential steps in our growth journey. She shares personal insights and biblical reflections on how challenges can transform us when embraced with faith.Key Topics:The connection between breakdowns and breakthroughs, emphasizing that breakthroughs often follow life's hardest seasonsHow unforeseen setbacks serve as preparation for future success and growthThe importance of patience, resilience, and faith during difficult timesThe significance of releasing fear, old habits, and control to make space for new blessingsRecognizing that breakthroughs come in many forms—mindset shifts, healing, wisdom, confidence, and peacePractical encouragement to keep moving forward despite delays or disappointmentsTimestamps:00:00 - The core message: breakthroughs follow hard seasons00:30 - Why we often pray for quick breakthroughs and God's timing01:26 - Defining breakthroughs: what truly signifies progress02:24 - The role of setbacks and disappointments in life02:54 - Lessons hidden within trials that foster growth03:24 - The analogy of seeds and growth through destruction03:51 - How difficulties teach patience, resilience, and trust04:16 - Discovering strength, faith, and God's presence during trials04:44 - Encouragement for those feeling discouraged or on the verge of quitting05:10 - Breakthroughs often occur right after giving up05:39 - The necessity of releasing fears and old habits to grow06:09 - Growth rarely happens in comfort zones06:39 - The value of life lessons learned through challenges07:07 - Shifting focus from asking "Why?" to "What can I learn?"07:36 - How lessons transform problems into opportunities for growth

Eric Zimmer is the author of How a Little Becomes a Lot and host of The One You Feed podcast, where he explores how intentional choices, practiced daily, lead to meaningful change. Top 3 Value Bombs 1. Breakthroughs don't create lasting change; consistent, small actions practiced daily do. 2. Change is not a character trait; it's a skill that can be learned and improved over time. 3. The question "What do I want now vs. what do I want most?" can transform decision-making in critical moments. Visit the website to pre-order the book. Available on Amazon, Barnes & Noble, and local bookstores - How A Little Becomes A Lot Sponsors HighLevel - The ultimate all-in-one platform for entrepreneurs, marketers, coaches, and agencies. Learn more at HighLevelFire.com. Plaud - The world's number 1 AI notetaking brand. Check out Plaud.ai/eof and use code EOF for 10 percent off.

This week on Catalyst, Tammy is joined by Sezin Palmer, AI Solutions Leader at NTT DATA in North America. Sezin traces her impressive and unconventional journey from CIA analyst and Navy submarine warfare programs to building the National Health Mission area at Johns Hopkins' Applied Physics Lab from scratch, then leading health AI and data at EY. Tammy and Sezin dig into the democratization of AI and what it means that capabilities once locked behind years of data science training are now accessible to nearly anyone. They also discuss the thorny challenge of how organizations decide what not to build and why the hardest leadership problem right now isn't launching AI, it's knowing when to stop. Sezin also shares her vision for what has her most excited: the convergence of software, robotics, and biology. Please note that the views expressed may not necessarily be those of NTT DATALinks: Sezin Palmer Learn more about Launch by NTT DATASee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episode 302: This week's episode AI is moving beyond answering questions — it's beginning to rewrite the systems beneath itself, raising a critical question: who builds the brake pedal when autonomous agents start making decisions at scale? We pair that warning with tech that inspires and unsettles, from NASA's Nancy Grace Roman Telescope launching early to Microsoft testing office‑focused AI hardware that sparks immediate privacy concerns. Gwen Way also spotlights the Roro Lee Pocket AI and the real implications of recording‑consent laws and cloud‑stored data.We round things out with the cultural side of automation: Hinge's AI conversation starters, Instagram's AI support bot missteps, and Hasbro testing AI personalities for classic characters. A full hour of tech news with real‑world takeaways, not hype this is the episode you don't skip all coming up on TechTime Radio, with a little whiskey on the side.-- Full Episode Details:AI isn't just answering questions anymore, it's starting to write the system underneath itself, and that should make every tech user pause. We kick things off with a stark warning from inside the AI world: if the industry only has a gas pedal, what does a “brake pedal” look like, and who gets to press it when autonomous AI agents start making decisions at scale?From there, we keep it moving with tech that feels hopeful and tech that feels invasive. We talk NASA's Nancy Grace Roman Space Telescope launching ahead of schedule and why its massive field of view could reshape what we know about dark energy and galaxy formation. Then we come back down to Earth with Microsoft testing AI hardware for office workers, including a wearable badge concept that raises immediate privacy questions. Gwen Way joins us for Gadgets and Gear with the Roro Lee Pocket AI agent, a Kickstarter device designed to capture meeting notes and turn them into action plans, plus a straight talk moment about recording consent laws and where your data really goes when “the cloud” is involved.We also hit the cultural side of automation: Hinge rolling out AI to help people start dating conversations, Instagram's AI support bot creating a security mess, and Hasbro experimenting with AI chatbots for icons like Optimus Prime and Mr. Potato Head. Add a whiskey tasting of Arbeiki 1794 Highland Rye Single Grain Scotch and you've got a full hour of tech news for everyday people with real takeaways. If you like the show, subscribe, share it with a friend, and leave a review so more listeners can find us.Send us Fan MailSupport the show

Why do so many people remain stuck even when they genuinely want change? In Episode 2 of Breakthrough Revolution Season […] The post Why Most People Don't Experience Breakthroughs in Their Lives appeared first on Breakthrough Revolution with Free Setrana.

Lisa Salberg and Dr. Alex de Feria explore the latest developments in HCM care, from promising non-obstructive HCM therapies to the challenges of recognizing symptoms, managing medications, and assessing sudden cardiac death risk. They also discuss clinical trials, fibrosis research, and why the future of HCM treatment has never looked brighter.   This conversation was recorded May 28, 2026.

The Smart 7 is an award winning daily podcast, in association with METRO that gives you everything you need to know in 7 minutes, at 7am, 7 days a week...With over 20 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day and the Sunday 7 won a Gold Award as “Best Conversation Starter” in the International Signal Podcast Awards If you're enjoying it, please follow, share, or even post a review, it all helps...Today's episode includes the following guests:Doctor Robert Stein - Professor of Breast Oncology at University College LondonSusan Galbraith - Head of Oncology Research and Development, AstraZenecaDr Rachna Shroff - Associate Director of Clinical Investigations at the University of Arizona's Comprehensive Cancer CentreJames Murray - The UK's Health Secretary Phil Hopkins - Critical Care Consultant, Kings College Hospital, London Will Guyatt - The Smart 7's Tech Guru Celeste Saulo - Secretary General of the World Meteorological OrganisationAntonio Guterres - Secretary General of the United Nations Carlos Nobre - Brazilian climate scientist and meteorologistKate White - Uk's Minister for Climate John McFall - former Paralympian and future British Astronaut Hedley Aylott - Co-Founder of Home Harvest Andrew Johnson - Co-Founder of Home Harvest Tom Cheesewright - Advanced FuturistFrank Maixner - Director of the Institute for Mummy StudiesContact us over @TheSmart7pod or visit www.thesmart7.com or find out more at www.metro.co.uk Presented by Lucie Lewis, written by Liam Thompson, researched by Lucie Lewis and produced by Daft Doris. Hosted on Acast. See acast.com/privacy for more information.

Bongani Bingwa speaks to Professor Tulio de Oliveira, recipient of the Order of Mapungubwe in Gold, about promising new HIV treatments, the latest Ebola outbreak, and South Africa's growing influence in global scientific research and public health. 702 Breakfast with Bongani Bingwa is broadcast on 702, a Johannesburg-based talk radio station. Bongani makes sense of the news, interviews the key newsmakers of the day, and holds those in power to account on your behalf. The team brings you all you need to know to start your day Thank you for listening. Listen live on Primedia+ weekdays from 6 am to 9 am (SA Time) https://buff.ly/gk3y0Kj For more from the show and catch-up podcasts, visit Primedia+ here https://buff.ly/zEcM35T Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Let’s keep the conversation going online: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 See omnystudio.com/listener for privacy information.

What's up all you stoners! Mr. and Mrs. Weedman are back with another round of cannabis headline news, medical marijuana research, industry updates, and a few stoner stories along the way—all in an effort to #StompTheStigma and #FreeThePlant.Before diving into the news, they get normal while seshing on some Black Maple from Soil Syndicate. This week, Mr. Weedman discusses whether cannabis consumers still hide their use, a major new study published in JAMA Network Open, and the growing battle over federal marijuana rescheduling, hemp regulations, and cannabis business reforms.Mrs. Weedman breaks down a medical cannabis guide for new patients, reviews research showing significant pain relief for fibromyalgia, rheumatoid arthritis, and osteoarthritis patients, and explores a thought-provoking discussion about cannabis and Christianity.The duo also covers cannabis policy updates from across the U.S., veterans' access, hemp THC legislation, international cannabis developments, and the latest stories shaping the future of legalization.As always, expect cannabis advocacy, laughs, stoner stories, and organic conversation from Mr. & Mrs. Weedman as they break down the week's hottest weed headlines.Articles Covered: https://thefreshtoast.com/culture/do-cannabis-consumers-still-hide-their-use/https://internationalhighlife.com/medical-cannabis-guide/https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2848548https://www.marijuanamoment.net/cannabis-provides-significant-improvements-in-pain-for-fibromyalgia-rheumatoid-arthritis-and-osteoarthritis-patients-study-shows/?utm_source=flipboard&utm_content=Cpizzo721%2Fmagazine%2FMarijuana+Investinghttps://illinoisnewsjoint.com/illinois-legislators-pass-cannabis-omnibus-bill/#CannabisPodcast #MarijuanaNews #CannabisNews #MedicalMarijuana #CannabisLegalization #HempNews #420Podcast #WeedCulture #CannabisCommunity #Weedman420ChroniclesThanks for listening and supporting independent cannabis media. Support The Show: https://www.buzzsprout.com/283607/supportTWITTER: @weedman420podYouTube: Weedman420 ChroniclesEMAIL:  weedman420chronicles@gmail.comSHOP: www.eightdecades.comIG: @eightdecadesEMAIL: eightdecadesinfo@gmail.comMr & Mrs "get normal" seshing on: Black Maple from @TheSoilSyndicateCOPYRIGHT 2021 WeedMan420Chronicles©Suggestions? Questions? Chat with us here.Support the show

Our guests today are Ryan Jackson and Ned Weinshenker. We discuss a new CRISPR system that can be used to selectively kill cells, and some recent breakthroughs in the growing technology.

In this episode of Mind the Meds, Erica Marini, PharmD, highlights information from the European Stroke Organization Conference include encouraging data on asundexian(Bayer), a factor XIa inhibitor showing reduced recurrent ischemic stroke risk without increased bleeding, as well as positive results from three trials of tirofiban in acute ischemic stroke settings. On the multiple sclerosis (MS) front, Marini covers the FDA approval of ocrelizumab (Ocrevus; Genentech) for pediatric relapsing-remitting MS in children 10 and older, a new study supporting early use of high-efficacy agents in pediatric MS, and 2 Lancet publications on ocrelizumab — one examining higher weight-adjusted dosing (which did not improve disability progression) and one confirming benefit in a broader primary progressive MS population. She also briefly discusses PADOVA (NCT04777331), a phase 2b trial of prasinezumab in early Parkinson's disease, which failed to meet its primary end point.The bulk of the episode is a discussion with guest Millad Sobhanian, PharmD, BCPS, clinical pharmacy specialist in neurology at the University of Maryland, focused on Alzheimer disease. They cover dextromethorphan/bupropion (Auvelity; Axsome Therapeutics), newly approved in April 2026 for agitation associated with Alzheimer dementia. Sobhanian walks through key safety considerations—including additive NMDA antagonism if combined with memantine, cardiovascular risks from the bupropion component, and the ever-present black box warning on antipsychotics in dementia patients—while both note that the efficacy data, though statistically significant, shows modest clinical effect sizes compared to the threshold for meaningful within-patient change.The conversation then turns to lecanemab's subcutaneous initiation formulation (Leqembi Iqlik; Eisai, Biogen), whose FDA decision has been delayed to about August 2026 as regulators seek more data on bioavailability and ARIA monitoring in the at-home setting. Sobhanian shares his real-world perspective on anti-amyloid therapy, describing a patient population that is typically early-stage, high-functioning, and has a mean age of about 60 to 70 years, and emphasizing the pharmacist's role in expectation-setting around the modest but potentially cumulative slowing of cognitive decline. The episode closes with a thorough discussion of the April 2026 Cochrane review on amyloid-targeting monoclonal antibodies, which both Marini and Sobhanian find overly broad in its conclusions. They note limitations such as the inclusion of withdrawn agents like aducanumab (Aduhelm; Biogen), heterogeneous inclusion criteria across trials, and an 18-month study horizon that may be too short to capture the full benefit suggested by longer-term open-label extension data.Key Takeaways:1. New options for Alzheimer's agitation exist, but fit carefully into the treatment algorithm. Dextromethorphan/bupropion offers a novel NMDA-based mechanism for treating agitation in Alzheimer dementia, but its clinical effect size is modest, and it carries meaningful safety considerations—particularly around the bupropion component in elderly patients. Like all pharmacologic options in this space, it remains a later-line choice after nonpharmacologic interventions have been exhausted, and medication reconciliation is critical given its interaction potential with memantine and CYP2D6 inhibitors.2. Anti-amyloid therapies are imperfect but not ready to be written off. The April 2026 Cochrane review drew significant attention with its conclusion that anti-amyloid monoclonal antibodies produce only trivial cognitive benefits, but its findings are limited by the inclusion of older, withdrawn agents, heterogeneous trial populations, and an 18-month time horizon that may be too short to capture the full trajectory of benefit.3. The pharmacist's role in anti-amyloid therapy goes well beyond dispensing. As illustrated by Sobhanian's practice at the University of Maryland, clinical pharmacists embedded in neurology clinics play a critical role in patient selection, expectation-setting, ARIA counseling, and informed decision-making for patients considering anti-amyloid therapy—a complex, high-stakes treatment decision that these patients and their caregivers should never be navigating alone.

This is The Energy to Heal, your resource for all things Splankna, the faith-based inner healing modality that will help you achieve emotional freedom. In this episode, Laura Milliken welcomes Lisa Bright for a powerful conversation about family healing, generational strongholds, and the authority believers have in Christ to bring lasting change to their family lines. Many families find themselves trapped in repeating cycles of anger, addiction, fear, broken relationships, and emotional pain. In this episode, Lisa shares how God used Splankna, prayer, and biblical truth to help her address patterns that had impacted her own family for generations. Together, Laura and Lisa explore: What generational strongholds can look like in real life How emotional patterns can be passed down through family systems The role of prayer and spiritual authority in breaking unhealthy cycles Stories of restored relationships and transformed family dynamics Why freedom is possible even when problems seem deeply rooted How parents and grandparents can begin changing the trajectory of future generations Lisa also shares personal stories from her own journey, including how the Lord helped her navigate inherited anger, health challenges, and family brokenness. Her testimony is a powerful reminder that no family is beyond redemption and that lasting transformation is possible when we partner with God in the process. If you've ever looked at your family and wondered, "How do we stop repeating the same patterns?" this episode is for you.

Utah's closed fire season is officially here with above-normal wildfire risk statewide. A loyal customer steps up big for Sandy's Crown Burgers after a fire setback, and Volaris launches new direct flights from SLC to Guadalajara. Then — a lost cockatiel, how pigeons navigate with their liver, and Utah schools rolling out Google's Gemini AI for 680,000 students. Elon Musk is about to become the world's first trillionaire — but can his money buy friendship? Gen Z might be saving movie theaters, two major cancer drug breakthroughs are giving new hope, and we can't forget the travel chaos: a business-class malfunction and a Bluetooth speaker name that turned a United flight around.   Stream KSL NewsRadio LIVE: kslnewsradio.com/listen Watch on YouTube: https://www.youtube.com/@KSLBrightside Facebook: https://www.facebook.com/KSLBrightside Instagram: https://www.instagram.com/KSL_Brightside TikTok: https://www.tiktok.com/@ksl.brightside

On this episode of What's On Your Mind, host Scott Hennen dives headfirst into the controversial layers of North Dakota's upcoming election cycle. Scott exposes what he views as a deeply sinister motive behind the seemingly wholesome "free school lunch" constitutional ballot measure, tracing its massive financial backing straight to a militant pro-abortion group out of California. Later, Max Cassette, CFO of local ag-tech star 701x, joins the studio to show off their cutting-edge GPS solar ear tags—a brilliant piece of homegrown innovation that is revolutionizing cattle tracking, slashing calf mortality rates, and restoring sanity to ranchers. In the second half, Congresswoman Julie Fedorchak calls in to explain how she is fighting to codify common-sense flexibility into the EPA's burdensome Diesel Exhaust Fluid (DEF) regulations to save American farmers billions in costly repairs. Plus, Michael Mortensen maps out the University of Mary's historic upcoming 5th annual pilgrimage to America's only approved Marian apparition site, and Carter Eisinger of the Cass County Republicans drops by to give a live look at early voting data and outline why local municipal races are the ultimate battleground for property taxes. Standout Moments & Timestamps [00:01:01] The Million-Dollar School Lunch Scheme: Scott unpacks why an out-of-state special interest group is pouring massive money into a "mom and apple pie" free lunch ballot measure to quietly build a massive database of progressive voters. [00:02:12] Wealthy vs. Needy: Scott challenges the lack of means testing in the proposed legislation, arguing that wealthy families shouldn't have their children's meals heavily subsidized by average taxpayers. [00:03:29] Connecting the Ballot Dots: Callers and hosts debate the ultimate end game of the out-of-state funding, warning listeners that this "loss leader" measure is designed to pave the way for reshaping the state's constitutional stance on abortion and state spending. [00:06:22] Breaking News in the Gubernatorial Race: Scott drops live breaking news as the Republican party officially releases its candidates from previous conventions pledges, opening a highly competitive primary path for Lisa Dameth and Ryan Wilson. [00:07:36] 701x High-Tech Cattle Tracking: CFO Max Cassette introduces the XT Pro and XT Light ear tags, explaining how solar-powered cellular and satellite connectivity are changing livestock record-keeping from birth to processing. [00:09:41] Edge AI in the Pasture: Max explains how 701x bypasses the internet by utilizing "Edge Artificial Intelligence" directly on the ear tags to monitor calving behavior and spot sickness days before visual symptoms occur.…

Subhro Mallik and Jimit Arora explore how AI is shifting from hype to real enterprise value, highlighting operating model reinvention, agility, and a human+AI mindset to drive scalable business transformation.

We just got back from San Antonio hosting our second annual X Club Retreat, and honestly, I'm still riding the high. Four days with 86 of the highest-performing stylists and salon owners in the industry who are doubling and tripling their revenue, running multi-seven-figure salons, and doing $300,000 a year solo behind the chair, and I walked away with pages of notes I knew I had to bring back to everybody. Here's the thing about a room like that: there is no gatekeeping. It's almost like a competition of who can share the best strategy. And when you're surrounded by people operating at that level, the conversations get really real, really fast. In this episode, I'm sharing the biggest takeaways from our speakers, what it really costs to produce an event like this, the mistakes I made, and what I'm doing differently when we head to Park City, Utah in 2027. If you weren't in the room, consider this your seat at the table!   If you want to learn more about the event, our X Club and what that looks like, go to www.thrivingstylist.com/xclub/.  For those of you who are X Club members, I hope to see you in Park City, Utah next year, and if you're just looking to level up your business and want to learn more strategy, Thriver Society is always available to you at www.thrivingstylist.com/thriverssociety/.  If you need a tool to keep your numbers (and business!) organized, you'll want to check out our Wealthiest Year Yet Planner. Join the waitlist now at www.thrivingstylist.com/wealthiestyearyet/. The beauty industry is changing faster than ever. What worked in 2022 or even 2024 won't cut it in 2026, so are you ready? Grab our FREE 2026 TREND REPORT, The 2026 Must-Know Business Realities, Strategies & Trends for Stylists and Salon Owners now at https://thrivingstylist.com/mustknow/. Thriving Leadership Method hands salon owners a step-by-step strategy to implement an irresistible culture and create a powerful growth path…all while setting themselves up for structure and profit, and you can join the waitlist NOW at www.thrivingstylist.com/thrivingleadershipmethod/!  With Grow My Clientele Calculator, you'll get instant clarity on how many new clients you'll need to hit your 2025 financial goals! Enter just four numbers, and this tool will show you exactly how many new guests you need monthly and yearly to reach your target income. No guesswork or complicated math required, and you can get it now at www.thrivingstylist.com/growmyclientele/.   Do you have a question for me that you'd like answered in a future episode like this one? A great way to do that is to head over to Apple Podcasts and leave a rating and review with your question. I'm looking forward to answering your question on a future episode on the podcast!  If you're not already following us, @thethrivingstylist, what are you waiting for? This is where I share pro tips every single week, along with winning strategies, testimonials, and amazing breakthroughs from my audience. You're not going to want to miss out on this. Learn more at: https://thrivingstylist.com/podcast/ 

Sign up now to access the daily Notre Dame news and recruiting scoop on the Four Horsemen Lounge and all of the premium Notre Dame stories on IrishIllustrated.com!Get your first month for only $1.00 -- sign up today. What's on your mind?Talk about it at the Four Horseman Lounge Sign up for our FREE Notre Dame Newsletter Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

There are two competing trends in the global fight against HIV/AIDS. On the one hand, there has been tremendous progress toward reducing the number of infections and deaths from HIV/AIDS over the last twenty years. Scientific advances in treatment and prevention, new policy tools, and political and funding commitments have driven down HIV/AIDS to the point where it is possible to foresee an AIDS-free world in the not-so-distant future. On the other hand, over the last few years, that progress has suddenly come under threat. COVID upended HIV/AIDS programs in much of the world, and more recently, sudden and swift funding cuts, including from the United States, are shaking the foundation upon which previous decades of progress were built. On June 22 and 23, these two competing forces will come to a head at the United Nations, where diplomats are gathering for a major meeting on HIV/AIDS. According to my guest today, Mitchell Warren, the High-Level Meeting on HIV/AIDS at the UN presents a unique opportunity for multilateral coordination toward the goal of ending HIV/AIDS as a public health threat, but that goal may be stymied. Key countries that previously led the global fight against HIV/AIDS, including the United States, are stepping back from their leadership roles, potentially upending decades of progress. Mitchell Warren is the executive director of AVAC, an advocacy group. We kick off by discussing some of the exciting new scientific innovations that may accelerate progress toward ending HIV/AIDS as a public health threat, then have a discussion of how cuts in funding and eroding political commitments are hitting just as these promising new scientific innovations are coming online. We then have a long conversation about how this dynamic may play out at the UN — and what to expect from the High-Level Meeting on HIV/AIDS.

“Behind every breakthrough are countless failures no one ever sees—but that's exactly what makes progress possible.” Dr. Thomas Kaiser. When I have scientists on the podcast: they're some of the coolest, smartest, funniest people, and they're always willing (and excited) to explain what they do in ways you can actually understand. Dr. Tom Kaiser is no exception. He lives and works in Durham, North Carolina, and brings together an impressive mix of scientist, physician, and entrepreneur. His work focuses on designing better medicines using cutting-edge technology. He began his career at Emory University in Dennis Liotta's lab, working on antiviral drug discovery, and later helped pioneer early machine learning approaches in drug design. His research spans RSV, cancer, and neurodegenerative diseases, and he went on to earn his medical degree from the University of Oxford. Tom is now the co-founder and Chief Scientific Officer of Avicenna Biosciences, where he's leading the development of innovative therapies aimed at improving and saving lives. And my favorite detail from his bio? He ends it by mentioning the love of his life, his wife. I'll be honest, when I first met him, I told Dr. Kaiser he seemed like someone who must have been in a movie. He's just that cool. His Company: Dr. Thomas Kaiser shares the story behind his company's name, Ibn Sina, also known as Avicenna a true Renaissance figure of the Islamic Golden Age. A physician, philosopher, and scientist, Ibn Sina embodied the kind of multidisciplinary thinking that still drives innovation today. It's a powerful reminder that the roots of modern medicine, and the spirit of discovery stretch back centuries. The Part We Don't Talk About Enough Science is not a straight line. Not even close. Experiments fail. Clinical trials don't work. Hypotheses fall apart after years of effort. Funding can disappear. Progress can stall in ways that are frustrating and sometimes heartbreaking especially when patients are waiting. Dr. Kaiser speaks about this with a clarity and calm that really stayed with me. Because the truth is: scientists have to keep going anyway. They carry the weight of those disappointments and start again. They adjust, rethink, rebuild, and try again. Over and over. And that persistence? That's where breakthroughs come from. From the outside, it's easy to celebrate the wins ... the new drug, the successful trial, the headlines. But behind every one of those moments are countless failures no one ever sees. For families like ours, waiting, hoping, advocating it matters to understand that this difficult process is also what makes progress possible. Living the Dream What if you actually got to live the dream you had as a kid? In this conversation, Dr. Thomas Kaiser shares something surprisingly personal: he feels lucky to be doing exactly what he dreamed of as a child. That early curiosity grew into a career designing new medicines and pushing the boundaries of science. From imagination to impact, his journey is a reminder that sometimes those childhood passions really can shape the future. Go to Dr. Kaisers website:  https://www.avicenna-bio.com Like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredNew: Shop our merchandise! https://thebonnellfoundation.org/product-shop/Thanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

In this episode of Contract Heroes, hosts Marc and Pepe welcome back Laurie Ehrlich, a legal leader who has navigated the full spectrum of the industry, from steering the "battleship" at global enterprises to leading a lean startup through a major acquisition. Laurie shares her whirlwind journey as the former Chief Legal Officer at Dioptra and her current role at Icertis following their acquisition of the startup in late 2025. She provides an insider's look at how Dioptra's agentic AI tools are being rebranded as Vera Engage and integrated into the Icertis suite to revolutionize contracting efficiency.

This message was inspired by Susie's book "Waking Up to the Goodness of God." Check out Susie's new podcast God Impressions on Apple, Spotify, or wherever you listen to podcasts! Faith Radio podcasts are made possible by your support. Give now: click here

In this Virgin Island Season 2 recap, we're breaking down Episodes 5-8 and the biggest moments from the series so far. From emotional breakthroughs and confidence-building exercises to first intimate experiences and life-changing therapy sessions, the contestants continue their journey to overcome fears, anxiety, body image issues and relationship challenges.We cover the key developments for Bertie, Katie, Tegan, Joy, Will and the rest of the cast, including the most emotional moments, surprise breakthroughs and major milestones that had viewers talking.⭐ Biggest breakthroughs⭐ Contestant progress updates⭐ Emotional therapy sessions⭐ Intimacy and confidence challenges⭐ Key moments from Episodes 5, 6, 7 & 8If you're watching Virgin Island Season 2 on Channel 4, this is your complete Episodes 5-8 breakdown and review.#VirginIsland #VirginIslandSeason2 #Channel4 #RealityTV #TVRecap #EpisodeBreakdown #RealityTVReview #VirginIslandRecap #Channel4Reality #TVDiscussion

Last week: Timothy Clark's four stages of psychological safety. This week: what they're missing.Most teams that believe they have psychological safety are stuck in a place where everything looks safe but nothing moves.TWO DIMENSIONS, NOT ONEPsychological safety has two distinct dimensions. Most frameworks address only one.Relational safety: How safe do team members feel with each other? Can they be candid, vulnerable, direct?Environmental safety: How safe does the environment feel? Familiar room, known routines, predictable structures.These two axes create four zones.ZONE 1 — THE DANGER ZONE (low / low)Toxic environment, hostile colleagues, chaotic, no trust. Individual: leave. Leader: act now.ZONE 2 — THE PSEUDO SAFETY ZONE (high environmental / low relational)The trap most "psychologically safe" teams are actually in.Everything looks fine. Names on doors. Clear meeting structures. Everyone knows the systems. But nobody addresses conflict, nobody has the hard conversations, nobody pushes."It's an area where we feel okay, but nothing gets done in a way that moves the needle. Most people have already signed out—within themselves."ZONE 3 — THE CRUISING ZONE (high / high)Clear structure, trusted colleagues, hard conversations possible, listening genuine. Aim to be here 60–70% of the time.But the big steps don't happen here.ZONE 4 — THE GROWTH ZONE: THE FIFTH STAGE (low environmental / high relational)Breakthroughs only happen when you deliberately remove environmental safety—and the relational safety is strong enough to hold the team together without it.Warren Bennis, in Organizing Genius, showed this with case after case. Breakthrough innovation happens when small teams of people who trust each other are taken outside the big company and thrown into a garage. They no longer care about environmental safety. They are too deep in the work.When Steve Jobs returned to Apple, he took his most trusted engineers to a different building and raised a pirate flag. Inside the original Macintosh, the engineers' signatures are moulded into the metal—where nobody could see them. They didn't need anyone to.HIGH-PERFORMING TEAMS DON'T LASTJon Katzenbach (The Wisdom of Teams): high-performing teams exist for days, weeks, sometimes months. Never years."I ask leadership teams: what kind of team are you? They say: a high-performing team. I say: for how long? And what for?"The Fifth Stage is the same. You go there for the breakthrough, then return to the Cruising Zone to recover. Then, if needed, go again.THE TRAINING INTERVENTIONA five-day leadership course for consultants. The first two days deliberately build both kinds of safety—familiar room, breakout structures, personal stories, shared meals.Wednesday morning: participants arrive to find the room destroyed. Everything overturned. Death metal at full volume."Most teams aren't ready. They run around like headless chickens. Some set up a desk and start working alone. Some go for another coffee. Rarely does the whole team come together, clean up, and start the morning themselves."The exercise tests one thing: when environmental safety is gone, is relational safety strong enough to hold?THE TAKEAWAYNo breakthrough happens in the same environment a team has always worked in. To unlock innovation, transformation, or change, environmental safety has to come down—but only after relational safety has been deliberately built.Build the Cruising Zone first. Visit the Fifth Stage when the breakthrough is required. Return.REFERENCES:Clark, T. R. The 4 Stages of Psychological Safety.Edmondson, A. The Fearless Organization.Bennis, W. Organizing Genius.Katzenbach, J. R. The Wisdom of Teams.LINKS: bernhardkerres.com | roleplays.ai#FifthStage #PsychologicalSafety #Leadership #Teams #Coaching

For decades, one of the biggest challenges of sending humans to Mars hasn't just been getting there, it's getting back. Under current mission plans, astronauts could spend nearly three years completing a round trip to the Red Planet. The journey to Mars alone typically takes seven to ten months, and crews then have to wait for Earth and Mars to align again before returning home. But now, an accidental discovery published in the journal Acta astronautica and inspired by asteroid trajectories suggests that future Mars missions might one day take less than a year-round trip. The idea came from a scientist who was studying near-Earth asteroids - specifically how scientists estimate their trajectories when first discovered. One asteroid caught his attention: 2001 CA21. Early calculations suggested the asteroid followed an unusual orbital path that crossed both Earth's and Mars' orbital regions. Later observations refined the asteroid's true trajectory, and the original estimates were essentially discarded. But the scientist noticed something fascinating hidden inside those early calculations. The geometry of the asteroid's path hinted at an ultra-fast route between Earth and Mars. Mars is much farther from the sun than Earth, and the planets are constantly moving around the sun at different speeds. To save fuel, spacecraft usually travel along carefully timed transfer orbits that take advantage of planetary alignment. These efficient routes are slower but practical. The problem is timing. Earth and Mars only line up properly for these fuel-efficient missions roughly every 26 months. Missing the return window means astronauts could be stranded waiting for another alignment. Using the new asteroid-inspired geometry, the researchers calculated that an extremely fast route to Mars could theoretically take as little as 34 days. The spacecraft would need to travel at around 32.5 kilometres per second which is far beyond the capabilities of current rockets. Also, arriving at Mars would be even more challenging. The spacecraft would hit the Martian system traveling so fast that current landing technologies couldn't safely slow it down. So while the 34-day mission is mathematically possible, it remains impractical with today's technology. Rather than focusing on the impossible extreme case, the researchers explored whether similar geometric paths could work during future Mars alignments using technology that may exist in the near future. And one opportunity stood out: the 2031 Mars opposition. According to the calculations, astronauts could potentially complete a round trip to Mars in about 153 days (roughly five months), or a lower-energy version lasting around 226 days (about 7.5 months) That's still dramatically shorter than the multi-year missions currently envisioned. The proposed mission profile would involve: A 33-day trip to Mars About one month on the Martian surface A 90-day return journey to Earth NASA's NASA probe New Horizons became the fastest spacecraft ever launched from Earth when it left for Pluto at around 16.26 kilometres per second. Future rockets like SpaceX Starship or Blue Origin New Glenn may eventually push those limits even further. One of the most fascinating parts of this story is that the discovery wasn't the result of a grand Mars mission plan. It came from a scientist noticing something unusual in old asteroid calculations that everyone else had moved past. Breakthroughs don't always emerge from people searching directly for answers. LISTEN ABOVESee omnystudio.com/listener for privacy information.

Broadcasting LIVE from Italy during his European screening tour for “An Inconvenient Study,” Del investigates the country that became the global symbol of COVID fear and lockdowns.Early in the pandemic, Italy became the image that terrified the world. Del sat down with frontline doctors, journalists and scientists across the country to investigate the mortality data, hospital incentives, media narratives, vaccine injuries, and political pressures that mysteriously shaped the global response to the pandemic.We also break down the latest attacks on MAHA, Del's public disagreement with RFK Jr. over the PREP Act, new nature-based immune therapies for cancer, and the ongoing fluoride battle.Guests: Prof. Alberto Contri, Dr. Mariano Amici, Dr. Rosanna Negri, Raffaella Regoli, Giovanni Trambusti, Dr. Pietro Gasparoni, Dr. Giuseppe Barbaro, Dr. Alberto DonzelliBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

In today's episode I am joined by astrologer Lauren Hansen and Human Design specialist Yvette Mayer for our monthly energy update, weaving astrology and Human Design to help you navigate what's coming.May brought it for all of us. We open with a real debrief on Uranus into Gemini, the Sagittarius full moon, and why the last two weeks hit so hard for so many people. Then we move into June.We cover the Venus-Jupiter conjunction on June 9th, the most expansive transit of the year and why it lands right when the channel of money is activated in Human Design. The Gemini new moon on June 14th and what it opens up. Mercury's pre-retrograde shadow phase kicking in on June 12th and what to sort out before it hits. Venus moving into Leo and what stirs in love, desire, and self-worth. The Mars-Uranus conjunction at the end of the month and why you'll want to slow down even when everything in you wants to move fast. And the Capricorn full moon on the 29th, what it brings to the surface, why it can feel like pressure, and how not to be too hard on yourself when it does.If you've been in the thick of it lately, this one will help you make sense of why.I trust you will get what you need from this episode, and make sure you come let me know how it resonated with you on instagram @the_human_design_coachBig love,MxxLauren's Details:Website: https://www.astrobetch.comInstagram & TikTok: @astrobetchWorkshop - Outer Planets & Your Birth Chart (June 14th, $15)Yvette's Details:Website: https://www.yvettemayer.comInstagram: https://www.instagram.com/yvettemayer_YouTube: https://www.youtube.com/@humandesignformarketingFacebook group: https://www.facebook.com/groups/humandesign4marketingPodcast: https://www.yvettemayer.com/podcastAs mentioned in the episode...watch Yvette's video here: https://www.instagram.com/reel/DYiR83OTyu6/?igsh=ZXVzMTRkZ3dwczQ1BodyGraph Chart SoftwareCreate your own Human Design chart tool with BodyGraphChart! Embed a chart tool on your own website, so you can engage with your leads, grow your business, teach Human Design the way YOU want to teach it and create success!Get BodyGraphChart here: https://bodygraphchart.com?via=emmadunwoodyUse the code humandesignpodcast for 30% off for 6 months!OTHER RESOURCESWant more on Human Design? Explore the ways to get involved below:Get Your Free Human Design Chart: https://www.emmadunwoody.com/get-your-chartThe Feminine Success Framework: https://www.emmadunwoody.com/feminine-success-frameworkMAGGIE - Magnetic by Design AI: https://meetmaggie.co/The HDx Collective: https://www.emmadunwoody.com/collectiveHuman Design Unhinged: https://www.humandesignunhinged.com/Secret Podcast: The Human Design Podcast (Off The Record): https://thehumandesignpodcast.supercast.com/Instagram @the_human_design_coachMusic: Spark Of Inspiration by Shane Ivers - https://www.silvermansound.comSupport the show

Traditional medicine is transitioning from pharmaceuticals to advanced cellular signaling. Caleb Granger discovered that most stem cell treatments fail because the cells die almost immediately after being introduced.  The Signal Driven Secret to Healing The real power lies in the messengers those cells release before they disappear. These tiny particles, known as exosomes, carry thousands of signals that instruct local cells to begin repair. Solving the Math Problem of Aging Aging is essentially a math problem involving healing capacity versus the rate of decline. When we are young, our bodies are flooded with millions of regenerative signals that fix injuries rapidly.  As years pass, the number and potency of these signals drop while inflammation increases. When you raise regenerative capacity past the rate of degeneration, the body begins to heal regardless of age. Recharging Your Cellular Energy Source Cells require a specific energy molecule called NAD plus to function properly. These levels plummet as we get older, leaving our bodies with less power to execute healing instructions.  Most traditional treatments fail because they cannot deliver this molecule directly into the cells. New protocols can restore these energy levels to their youthful peak in just a couple of months. Real World Results and Tissue Regeneration This signal-based approach has produced remarkable results for thousands of individuals across the country. One striking case involved a patient who regained speech after being nonverbal for four years. Another patient saw a significant restoration of kidney function that had been failing for seven years. These improvements demonstrate that cellular instructions can essentially reset the body to a higher baseline of health. In this podcast, you will discover... Why most stem cells die quickly The secret to reversing decline How exosomes deliver healing signals The truth about cellular energy Why current treatments often fail How to regrow actual tissue   EPISODE RESOURCES: Website Instagram TikTok

BiTEs or bispecific T-cell engager antibodies are an emerging class of therapies with significant potential to advance cancer treatment. Pharmacists will play a key role both in the utilization of these agents but also in the mitigation and management of the unique toxicities that accompany them. This podcast provides insights into the patient care needs and novel interdisciplinary models employed to support patients receiving BiTE therapies. Listeners will gain key insights into BiTE therapies, including their role in treatment, the current pipeline, and safety considerations. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

On this episode of The AI Report, synthetic anchors Artie Intel and Micheline Learning break down the wild new world of AI agents that don’t just chat, they work, build, and make decisions across your apps, clouds, and companies. From powerful new multimodal models and creative video tools to lab‑grade scientific copilots and the first serious wave of global AI regulation, this 5‑minute newscast packs in the hottest developments shaping how humans live and work with machines. With Artie’s occasional razor‑sharp sarcasm and Micheline’s dry wit, you’ll get a fast, punchy tour through the latest tools, breakthroughs, and rulebooks defining the future of artificial intelligence on planet Earth. 

Somewhere, someone in the world is pushing the frontiers of medicine. And today that someone is Dr. Dayan Goodenowe, the pioneer of plasmalogen medicine. His stories of clinical success deploying his very own patented plasmalogen molecules are incredible. Curing blindness. Reversing dementia. Growing brains. And his idea is simple. We are all equipped with the right biological software but often lack the biochemical raw material to thrive. Dr D and plasmalogens are changing that.Dr. Dayan Goodenowe, PhD, is a neuroscientist, biochemist, inventor, and clinical research expert. In 1999, he invented and patented ion cyclotron resonance mass spectrometry technology, enabling comprehensive monitoring of human biochemistry for the first time. Using this technology, Dr. Goodenowe analyzed blood samples from tens of thousands of individuals of all ages and races, from multiple countries. Over 20 conditions were studied, including autism, dementia, colon cancer, heart disease, and others. Differences between the biochemistry of younger and older populations, as well as associations with all-cause mortality, were also examined. This body of research identified early biochemical patterns associated with disease and mortality risk, thereby contributing to the development of an extensive patent portfolio. These patents cover diagnostic tests for early detection and screening across numerous conditions, including specific cancers, neurological disorders, psychiatric conditions, and cardiovascular disease.Contact:Website - https://prodrome.com Website - https://drgoodenowe.comWebsite - https://perpetualhealth.drgoodenowe.comExcited by the sound of these incredible molecules. Start your plasmalogen journey with Dr Dayan and Prodrome with a 25% discount using code STAVS25Join us as we explore:The science of plasmalogens - what they are, how they work, who should use them and why they hold revolutionary medical potential.The most important plasmalogens for cognitive health and mental performance.What makes Prodrome plasmalogens different from conventional omega 3 and 9 products. Why nobody is escaping the shrinking brain problem…without plasmalogens.Miraculous results with MS, autism and ALS patients.Dr D's unique brain imaging and assessment, why standard MRI are not reliable neurologically and how plasmalogens reverse brain aging and grow your brain.Traumatic brain injuries, concussion prevention and cureSupport the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

In this episode, we explore the often-overlooked gap between creating meaningful work and actually releasing it into the world. Starting with the story of Vivian Maier—the prolific street photographer whose life's work was discovered only after her death—we examine why so many of us hesitate to share our creations.We're joined by Tina Roth Eisenberg, founder of Creative Mornings, who discusses the power of community, commitment, and collective bravery. She introduces Release Day, a campaign challenging creatives everywhere to choose a deadline, finish neglected projects, and courageously share them with the world—no matter how imperfect.In the second half, we speak with John Gordon, author of The Power of Positive Habits, to dissect how small, consistent daily practices shape who we become as creatives and leaders. John shares his philosophy on positive leadership, the unglamorous truth about habits, and how intentionally structuring our environment and thoughts can lower the friction to action.We close by connecting these two perspectives—shipping our best work isn't a grand gesture, but a daily discipline, and real change happens not by waiting for the perfect moment, but by deciding to act, together.Five Key LearningsUnreleased work has zero surface area for discovery: You increase opportunities for your work—and yourself—when you ship, even when it feels unfinished or imperfect (12:08, 29:30).Commitment beats option paralysis: The most fulfilled creative lives are built by long-haul loyalty to a community, a cause, or a craft, not by staying in the “hallway” of endless choices (07:09).Release is a team sport: Community-driven events like Release Day lower the psychological barriers to sharing, making bravery and celebration contagious (09:08).Big change is built from small habits: Tiny daily choices and routines—like preparing in advance, intentionally feeding your mind, or practicing gratitude—compound into transformative outcomes (22:44).Intentional reflection is non-negotiable: Leaders (and creatives) who carve out time for stillness, purpose, and intentional thinking show up with more clarity, courage, and meaning in their work (26:46).Get full interviews and bonus content for free! Just join the list at DailyCreativePlus.com.Mentioned in this episode:The Brave Habit is available nowMy new book will help you make bravery a habit in your life, your leadership, and your work. Discover how to develop the two qualities that lead to brave action: Optimistic Vision and Agency. Buy The Brave Habit wherever books are sold, or learn more at TheBraveHabit.com.To listen to the full interviews from today's episode, as well as receive bonus content and deep dive insights from the episode, visit DailyCreativePlus.com and join Daily Creative+.

Join the  Uplift Community App TODAY!  Some truths need to be heard more than once. Not because you missed them the first time, but because real change takes repetition. It sinks in slowly. It settles into your bones a little more each time until one day you realize you are living it instead of just nodding along. That is exactly why this episode exists. We are closing out the Emotional Health Series with a best of collection featuring the most meanin   I hope you loved this episode!

In this episode of the Risen Fallen Podcast, I talk about the trap of constantly waiting for a breakthrough.   A lot of us want the perfect plan, the big moment, the emotional shift, the viral post, or the sudden burst of motivation that finally changes everything. But most real growth does not happen that way.   Real change usually happens in the boring, repetitive, quiet work that nobody sees.   It happens when you keep showing up without applause. It happens when you stay consistent after the excitement fades. It happens when you stop chasing the feeling of starting over and actually commit to the slow rebuild.   This episode is about discipline, consistency, self-development, mental health, business, fitness, faith, and learning how to trust the process when it does not feel exciting anymore.   Because the boring part is not the part before your life changes.   The boring part is the part that changes you.   If you liked the show, help it grow!   Leave a review and rate 5 stars on Apple Podcast, and Spotify!

Welcome to Friday Coaching Clinic Episodes. These are LIVE coaching session snippets where you have the opportunity to learn as both client and coach. I encourage you to think about how you might coach through this topic as a coach or how this situation may support you as a client. A reminder about these episodes: This snippet is just one way of coaching through this topic. Each coach has their own unique voice, personality and confidence to best support their clients and I invite you to find yours.  This week: Turning No-Shows into Breakthroughs

In this episode of The Scoop, Margy Eckelkamp sits down with Hunter Carpenter from the Agricultural Retailers Association to break down the critical policy shifts currently moving through Washington, D.C. The conversation centers on the House-passed Farm Bill, highlighting key wins like the TSP Access Act and the new plant biostimulant definition. However, Hunter also addresses the "hiccups" in the House version, specifically the removal of language regarding uniform labeling and NPDES permit reforms—issues the ARA hopes to revive in the Senate. The episode further explores the House's recent passage of year-round E15 sales. Beyond legislation, Hunter discusses the ARA’s cautious stance on the proposed Union Pacific and Norfolk Southern rail merger, emphasizing that maintaining competition is vital for keeping freight rates manageable for retailers.See omnystudio.com/listener for privacy information.

https://youtu.be/tU0kHdf7oXo Drew Allen, CEO of Grace Technologies, is driven by a mission to lead a life of adventure and impact. At Grace Technologies, that impact is tangible: the company develops electrical safety and predictive maintenance solutions that help industrial teams prevent downtime, improve productivity, and, most importantly, send workers home safely at the end of the day. We explore Drew's Product Engineering Framework — Clarify the Problem You're Solving, Understand the Constraints, Think from First Principles, Build a Prototype, and Iterate within a Time Limit — a practical approach to innovation in technical product development. Drew explains why rapid iteration beats overbuilding, how constraints can unlock better engineering decisions, and why time-boxing product development prevents teams from getting stuck in endless perfectionism. He also shares how Grace Technologies is expanding into the data center market, where rising power density is creating new safety challenges and new opportunities for growth. — 5 Steps to Engineering Breakthroughs with Drew Allen  Good day, dear listeners. Steve Preda here with the Management Blueprint Podcast, and today’s guest is Drew Allen, the CEO of Grace Technologies—the leading innovator of electrical safety products and predictive maintenance solutions that help companies maximize productivity and foster a safety culture. Drew, welcome to the show.  Hey, thanks for having me, Steve. I’m excited. I’ve really enjoyed your books, and they’ve had a big impact on our business. So it's great to have this conversation today.  Yeah, glad to have you here. So if you enjoyed the book or read Pinnacle and Summit OS perhaps, then you’re going to be familiar with this question. What is your personal “Why,” and how are you manifesting it Grace Technologies?  So my personal “Why” is to lead a life of adventure and impact. And I think that manifests in our company. We try to be as innovative as possible. Typically, around 30% of our annual sales come from products released within the last two to three years. We try to take risks, not in kind of a willy-nilly way, but we try to be smart about our risk-taking, but still make sure that we’re taking risks and we’re on the forefront of the technology edges. In our business, it’s really easy to see the impact that we have. Not many businesses get to say that we literally send people home at the end of the day. We literally save lives, and we don’t take that responsibility very lightly. And so it’s a little way that we can kind of make a dramatic impact in the world. We get a lot of stories of people who have been going to go to work on an electrical system. They were just moving throughout their day, trying to do their work, and all of a sudden they saw that our unit was indicating and they were about to put their hand on that bus bar or that cable, and they stop and realize, “Oh, there's still power there.” And they could have been either severely injured or dead. And so we get those stories quite frequently, and so it's really impactful to hear that, to know that we're doing that kind of good in the world.Share on X  Yeah, I love that. And yes, I mean, it’s dangerous. My son actually worked for an electrical contractor last year, and they told him the story that they were in big industrial facilities and one of their workers was trying to fix a light and he got shocked. And the only way to save him was to kick the ladder out from under him. He ended up breaking his leg. So it was kind of funny story afterward, but also a very dramatic one at the same time. So yeah, you definitely want to avoid situations like that.  100%.  And I think what you do is really great, and focusing on the safety aspect is very important as well. What I'm wondering—because I'm a framework guy and I'm always looking for new frameworks people have developed—and obviously within the Pinnacle system there are a lot of frameworks. But you’ve been doing this for a few years, and I’m sure that you have come up with your own. So what is your favorite framework—something simple enough for listeners to understand in maybe three to five steps—that could help them improve their business?  My favorite framework really comes from Jim Collins' work on the Flywheel. And I think you reference it in your book as well, Steve. I think if people can see their business—or even their life—through the lens of a flywheel, it becomes really useful. So in our business, our flywheel is relatively simple. And I think there are probably only a limited number of flywheel models companies really operate under. Our version of a product flywheel works like this:  We start with amazing new products and services. If we do that well, we naturally excite our channel partners. When our channel gets excited, they can't help but get us specified by customers. Once we're specified by customers, it grows our revenues, unit sales, and customer base.Share on X And as that happens, it expands the power of the brand, which allows us to set high prices and deliver higher gross margins to be able to reinvest into R&D for amazing new products and services. And I think while maybe there’s a couple of pieces in ours channel-specific or whatever, we found that most of my focus as CEO is just constantly figuring out how do I push those pieces of the flywheel, and where is the current bottleneck in the flywheel? Is the bottleneck getting the specifications? Is the bottleneck the wrong product? One of the challenges in our business is that we have a 12-month product development cycle plus an 8-to-12-month sales cycle for products. So if I miss, I'm basically down for two years. And I don't really know it early enough unless I'm paying close attention to the leading indicators—which we've become much smarter about over the last few years. A lot of business people tend to focus only on lagging indicators, and they're not always clear on what the leading indicators are in their business—or how correlated those leading indicators are to the lagging results.  I'll say this: the most recent releases of Claude have made it incredibly easy to input a bunch of variables and figure out how strongly your leading indicators correlate with your lagging success. I probably haven't done that kind of work since college and deep regression analysis or logarithmic modeling. And now Claude makes it so easy. So if you can identify the leading indicators tied to your future success, and you know there's an 80% or 85% correlation, then that leading indicator is almost as valuable as the lagging indicator itself. And if your lagging indicator is revenue, that gives you a pretty strong signal about what you should actually be focusing on.Share on X Yeah. That's a great way to reverse-engineer those leading indicators from the outcomes you're targeting. I love that. So when you say that one of the flywheel cogs is for people to specify your product, what do you mean by that exactly? We come out with a product, and then we get meetings with large end-user customers. Okay? Our products are really sold into two major markets. One is the industrial market—everything from where things come out of the ground, like oil and gas, pulp and paper, and mining—to all the downstream processing industries, including automotive, tire and rubber, consumer packaged goods, food and beverage, all those kinds of industries like shipbuilding, naval yards, and all those kinds of environments. All of these places have complex electrical and control systems. And when a factory or facility is being designed or upgraded, someone is writing a specification document.  That specification literally defines how everything should be built—including the machinery and the electrical systems. So we want to make sure our products, from an electrical safety perspective, are included in those specification documents. We've been really fortunate to get into some of the world's largest companies' control specificationsShare on X companies like Amazon, Procter & Gamble, GM, and Ford. These large organizations really see the value in our products from both a productivity and a safety standpoint. And that's really the key to our success: driving specifications with large end-user customers. Yeah. So it sounds like when you get specified, then essentially you’re baked in to their product, and then you kind of have, at least for the time being, you have a monopoly of supplying them. Is that the case?  Yeah. And some specifications are a little more open. They may specify our type of device, or they may even list competitors as alternatives. And then it becomes a little more of a street brawl when we're competing. But either way, we want to grow the overall market for products like ours—not just our own products—because we're in the safety business. And I think it's really shortsighted to be selfish about that. I think we have much more opportunity if the overall pie grows than if we focus only on increasing our individual slice of the pie. Of course, I'm going to do the best I can to grow our share. But ultimately, electrical safety and electrical reliability in factories are still major problems. And the number of deaths, injuries, and life-changing accidents we hear about—it continues. We hear those stories all the time, and we don't want those things to happen. Yeah. Love it. So your business is innovation-driven, and you are designing these electrical appliances that increase productivity, reduce risk. What is the major success factor in being able to come up with new products along these lines?  Yeah, so I guess I'll tell you my biggest failure. Okay? I'll use the failure to illustrate the point. That's good. I think I was about 25 or 26 years old, and I was working with a customer—a very large publicly traded company. They liked our product, but they needed it in a different form factor, which meant we had to re-engineer the product, retool it, and go through all the certification processes again. And I just took it hook, line, and sinker. I thought we were really onto something. I probably had delusions of grandeur and thought I was some Steve Jobs-like figure who could just wave a magic wand. And by the way, I don't think that's actually what Steve Jobs did, so I want to put that out there for a minute. I think what we see from the outside as consumers is often not the reality inside the company. So I just want to say that.  But anyway, instead of taking small iterative steps and quickly prototyping and getting feedback, I did a full design based only on feedback from that one customer before cutting tooling and paying all the certification costs. It ended up being about a $400,000 project. And I think we still have inventory from that project—and this was probably 12 years ago or something.  Oh my gosh.  So what have I learned now? The best innovation happens through rapid iteration. A lot of your listeners have probably seen the Elon Musk SpaceX Raptor engine images, right? You have this incredibly complex engine that goes up into space, and then the next version looks much simpler, and the third one looks like it came out of a sci-fi movie. It's almost like the Picasso bull sketches.  There are nine different bulls until Picasso eventually gets it down to two lines, and you still understand it's a bull. Okay? And I think that's what iteration looks like. What you see as a final product from Apple is actually the result of thousands of prototypes, iterations, and constant testing behind the curtain. For me, I want to test with customers directly, because you get much better feedback that way. I think the more rapidly you can prototype, the more rapidly you can iterate and get real customer feedback, the more innovative your product is going to be. I really think that when you try to make too big of a leap all once, you usually can't get there. And I think 10% compounded over time is a much better strategy than trying to go 10X in a single shot. Yeah. It's kind of the Kaizen principle of continuous improvement through small steps. But actually, I was listening to an interview with Jensen Huang, and he said he hated Kaizen because he wanted more first-principles thinking—completely rethinking things from the ground up. And I think Elon Musk does that too. Although honestly, I think he does both, which is really interesting. But I love Kaizen. I think it's a wonderful concept to continually improve things. We do work with SpaceX. We don't do much with NVIDIA—a little bit, but not much. And while you can think from first principles, you still have to iterate on the prototypes, right? Yeah. You have to constantly try things. So you may have a first-principles vision of where you want to go, but you're not going to get there by designing the perfect thing 100% upfront. You get there through iteration. Yeah. So you really need both. That’s a really good point. So Drew, what is it that you are trying to figure out in your business right now?  So over the last 12 to 18 months, our largest orders have started coming through the data center sector. Back in 2015 or 2016, I tried to push into data centers, and we just had no product-market fit. None. Everybody kept talking about the data center business, and I was like, “Well, they're just not using our products. We tried…” But what suddenly changed was the increase in power density inside data centers. And what I mean by that is this: You can now have a hundred megawatts in a traditional data center hall. That's basically the equivalent of multiple oil and gas refineries worth of electrical load inside a single data center hall. A hundred megawatts—yeah.  And so the electrical risk profile has really changed. And because of that, now there is product-market fit. So now I'm trying to figure out: How do I set up the right distribution channels? How do I build the right sales network? Because data centers definitely buy differently than our traditional industrial customers. And then, as CEO, you always have to decide where you're going to focus your time. I've been very intentional about not losing the core identity of Grace through our industrial business. So I've had to build a separate group that really focuses on the data center market. That also means bringing in a board member who really understands the data center space. Right now, though, it's a huge growth area for us, so figuring that out has been super important.  The other thing is that over the last few years, we've launched an incredible number of new products. But a lot of those were what I'd call necessary innovations—things we had to execute on quickly. So now we're finally getting to a point with the engineering team where we can start from a clean sheet of paper again. We can think more deeply about where we really want to go—maybe even from first principles. Because honestly, I feel like we've been operating in a reactive mode for the last few years. So it's going to be really exciting to finally have some white space again and be able to innovate more intentionally for the future. Yeah. So you want to have that sci-fi engine for Grace Technologies that SpaceX has for the rockets, right?  Yeah. That's the goal. And our mission is to accelerate the industrial world to zero downtime and zero harm. Until we get there, it's a pretty lofty goal. And I think it's going to require a lot of innovation to achieve it. So what's the process when you're trying to get to that kind of innovation—when you're rethinking something from first principles? Is there a process you can follow or work through? Or is it more about letting your imagination wander? Like when Albert Einstein came up with the theory of relativity—he was daydreaming in the patent office and suddenly had these insights. What's your process for getting there? So first, we want to be really clear on the problem statement. Getting absolute clarity on what problem we're solving is the first step, right? If you don't know what problem you're solving, there's no amount of engineering you can throw at it that's going to make sense. Second is understanding the constraints. For one of our new product development efforts, we decided to move away from a digital platform and go to a fully analog electrical platform because we realized one of the main constraints was size. And size is really determined by the power supply.  When you run a digital circuit, you're operating at something like 100 to 300 milliamps. If you go to an analog circuit, you're operating at the microamp level. So you're literally at around 10% of the power requirement. And if you're at 10%, you can make the power supply about 90% smaller. Now, it's much easier to do things digitally because you just program the microcontroller. You're not dealing with the art of analog circuitry. So I think that's a good example of thinking from first principles. Okay—we're solving this problem. One of the major problems inside that problem is the size of the unit. How do we reduce the size? Well, we have to reduce the power supply. How do we reduce the power supply? Reduce the power draw from the circuit. How do we reduce the power draw? Go analog. And that's how we got there.  But even then, the amount of prototyping and iteration we've done on that over the last 12 months has probably involved 75 major iterations of the circuit, tons of prototypes, tons of testing, and countless tweaks that probably never even hit my radar. I know I'm getting a little nerdy for the podcast, but I think it's a really good example. And if you take it out of engineering for a minute and look at our sales engine, it works similarly. Ultimately, what drives sales? You have to have unique selling conversations with customers. So everything I focus on becomes: How do I maximize those conversations?  Getting people interested in the product and actually getting to the point where we can sit down and fully tell our story—that's kind of my North Star.Share on X I know that if we increase the number of those conversations, sales will increase. And of course, there's optimization on both sides of the meeting—follow-through, follow-up, competitiveness, lead quality, all of that. But the big North Star in our sales function is: How many unique selling conversations are we having with customers? Okay. I love it. So this is a framework that I’m more excited about than the flywheel because we are almost 400 episodes in. Here is what I heard. So be clear on the problem, step number one. Understand the constraints, step number two. Think from first principles, that’s step number three. Build the prototype, step number four, and perform iterations. Step number five, essentially the optimization. And with the sales engine, it’s kind of a similar process that you described, but less technical perhaps.  Yeah. And one other piece too is that all of this has to be time-constrained.  What do you mean by that?  I think people miss that point. If you don't have a time constraint, it will literally take forever. So inside of your framework, you need a time box, and I think that's really critical. I like what Elon says about timelines. He assigns timelines that he believes have about a 50% probability of being achieved. I think that's actually a really smart way to think about it. And that means that about 50% of the time, you're going to miss the target. But that's okay, because you want that level of tension and flexibility in the system. You still have to be aiming at something. If you don't put a time box around iteration, if you don't set launch dates, product development can drag on forever. For example, we have a major trade show every fall, and we always try to have products ready for that event. That creates a really effective natural time box for us. And if your business doesn't already have natural time boxes, then as CEO, you need to create them. Yeah.  Otherwise, iteration, product development, and even sales initiatives can lose momentum. Sales naturally has monthly, quarterly, and annual cycles. But in engineering especially, having that time box is really important. Yeah. And what I read about Jensen Huang is that one of the innovations he introduced was creating two overlapping time boxes. So instead of having just a single one-year cycle, he created two teams working on separate one-year cycles that were staggered by six months. That way, they could effectively iterate on the product twice as fast. I thought that was amazing. And I also had a client—an engineering software company—whose challenge was that they couldn't launch a product for three years because they were such perfectionists. So we talked about putting a stake in the ground and committing to a release every year. Maybe the scope would have to change, maybe they'd have to narrow it or simplify it, but the release date itself would become a forcing function. And once they did that, their product suddenly started gaining much more traction. That's a fantastic point. Yeah. I was advising one of the companies we're invested in. I was actually on a call with them yesterday, and they're starting to run out of time a little bit, right? And that was literally the conversation we had. “Okay, we had this wish list. We had this dream product-development idea. Now what can we realistically get done in three months?” So we started stripping out everything that couldn't be completed in that timeframe, and those items will move into the next iteration cycle. But I think it's super critical. You've got to put a stake in the ground and force things through. Yeah. Constraints create creativity. Yeah. that's fantastic. So, penultimate question—I have one more just to wrap things up. If you had a magic wand, what would be the one thing you'd want to fix inside your company over the next 12 months? I think we have a lot of relatively new and young salespeople. We operate in a very technical field, and trying to get them to really understand the application space from a technical perspective is difficult. And when you're selling to engineers, they can immediately tell if you don't know what you're talking about. So the challenge becomes: How do you compress 20 years of experience into a brand-new sales or business development person in just a few months? Trying to accelerate that learning curve is probably one of our biggest challenges. We're trying to use AI to help visualize the kinds of equipment our products go on.  And frankly, even after doing this for years, I still run into things I don't fully understand. But I have enough experience that I can have a relatively technical conversation, understand the constraints, and work through the problem set. But compressing that knowledge into a faster training process—that's definitely been hard. I'm also opening a sales and engineering office down in Austin, so I'll be moving there in June. The plan is to build out another R&D facility there. That's one of my major time boxes over the next 12 months—getting that operation fully up and running. But from a more holistic perspective, I think really solving that sales knowledge-transfer problem is critical. And on one of our product lines, honestly, I'd love ideas from listeners.  We have an IoT condition-monitoring product, and we've been very successful at selling pilot programs. What we've found, though, is that it's been much harder than expected to convert those pilots into broader expansion deployments. So we're asking ourselves: Are we making the barrier to entry for the pilots too low? Are we attracting the wrong type of customer—people who don't actually have the authority to make a larger purchase decision? Or are we missing something in the sales process that would better position the expansion after the pilot succeeds? Those are a few of the areas we're really trying to figure out right now. Yeah. Love it. That’s fascinating. So if the listeners would like to learn more about Grace Technologies—or maybe you spark something in their mind and they want to reach out and communicate to you, or have access to someone in your company to answer the questions about the products. Maybe they want to have more safety and more productivity with their electrical safety equipment. Where should they go, and where can they find you? Yeah. You can reach me at drewa@gracetechnologies.com or find me on LinkedIn. I think it’s Allen-Drew is my handle, but Drew Allen on LinkedIn. I love hearing from people. I really enjoy advising startups, especially in the industrial electrical space. If you have a product idea or you’ve got a startup, I do a lot of advisory work, and we’ve invested in a number of startups as well. We’re really passionate about having more innovation in the industrial world. I believe that the reindustrialization of America is super important, and I’m a big proponent, and so love to support companies that are doing cool things in our space.  Oh, that’s fantastic. So if you’re listening to this and you have a startup in the engineering space, then definitely this is your opportunity to get mentored by Drew, and maybe to get opportunities that you don’t have yourself. So reach out to him. And if you just enjoyed this conversation with an entrepreneur who’s innovating fast and who is working from first principles and time boxes and and leveraging constraints, then definitely stay tuned on this channel because I have more wonderful guests coming on every week. So thank you Drew for coming, CEO of Grace Technologies, the leading innovator of electrical safety products and predictive maintenance solutions. So thanks for sharing your wisdom and thanks for listening. Important Links: Drew's LinkedIn Drew's website Drew's email: drewa@gracetechnologies.com

President Donald Trump leaves Beijing claiming progress on trade and Iran after two days with Xi Jinping. But details of any new deals aren't coming from either side. Plus, the Supreme Court keeps the abortion pill available by mail. The legal fight over Mifepristone is still moving, but access stays in place for now. And Cuba's power grid is buckling after the country officially runs out of oil. Blackouts and protests are spreading across Havana as the CIA director quietly visits the island for talks. These stories and more highlight your Unbiased Updates for Friday, May 15, 2026.

In this episode, hosts dive into Canada's recent legal decisions against secession, aUFO revelations, and the unseen battles of global elites. Expect a no-holds-barred discussion blending conspiracy theories, emerging tech, and geopolitical shifts. Main Topics Covered: Canadian court decisions blocking Alberta's secession and impacts on treaty rights Eric Weinstein and the UFO disclosure debate, including recent Pentagon revelations The real story behind deep state meddling, global migration, and the UN's role Breakthroughs in energy tech with Casimir force microchips The alleged influence of global elites and secret societies on world events Key Insights: Alberta's court decision was based on law violations concerning Indigenous treaties and constitutional duties. UFO whistleblowers claim secret government projects that manipulate physics and the fabric of reality. Machete bins in Melbourne exemplify the bizarre measures in response to rising violence and migration. Casimir chips could revolutionize energy harvesting, powering devices from quantum vacuum energy. The movement of global elites, from Obama's secret meetings to Skandava's secret files, points to a hidden power network.   To gain access to the second half of show and our Plus feed for audio and podcast please clink the link http://www.grimericaoutlawed.ca/support.   For second half of video (when applicable and audio) go to our Substack and Subscribe. https://grimericaoutlawed.substack.com/ or to our Locals  https://grimericaoutlawed.locals.com/ or Patreon https://www.patreon.com/grimericaoutlawed   Support the show directly: https://open.spotify.com/show/2punSyd9Cw76ZtvHxMKenI?si=ImKxfMHgQZ-oshl499O4dQ&nd=1&dlsi=4c25fa9c78674de3 Watch or Listen on Spotify https://www.simulationmaps.com/#products Disaster Maps, Volcano Sim, Asteroid Sim, Shipwreck Map, UFO Map etc https://grimericacbd.com/ CBD / THC Tinctures and Gummies https://grimerica.ca/support-2/ Our Adultbrain Audiobook Podcast and Website: www.adultbrain.ca Check out our next trip/conference/meetup - Contact at the Cabin www.contactatthecabin.com Join the chat / hangout with a bunch of fellow Grimericans  Https://t.me.grimerica grimerica.ca/chats   Discord Chats Darren's books www.acanadianshame.ca Sign up for our newsletter http://www.grimerica.ca/news InstaGRAM https://www.instagram.com/the_grimerica_show_podcast/  Purchase swag, with partial proceeds donated to the show www.grimerica.ca/swag ART - Napolean Duheme's site http://www.lostbreadcomic.com/  MUSIC Tru Northperception, Felix's Site sirfelix.bandcamp.com    Links to the stuff we chatted about: https://x.com/riseofalberta/status/2054684899869876371?s=43%22%3Ehttps://x.com/riseofalberta/status/2054684899869876371?s=43%3C/a https://x.com/defazioivano/status/2054152047054717363?s=43%22%3Ehttps://x.com/defazioivano/status/2054152047054717363?s=43%3C/a https://x.com/junonewscom/status/2054611630625816776?s=43%22%3Ehttps://x.com/junonewscom/status/2054611630625816776?s=43%3C/a https://x.com/marcnixon24/status/2054622045762461791?s=43%22%3Ehttps://x.com/marcnixon24/status/2054622045762461791?s=43%3C/a https://x.com/ryangerritsen/status/2054716111808012453?s=43%22%3Ehttps://x.com/ryangerritsen/status/2054716111808012453?s=43%3C/a https://x.com/_pblanknews/status/2048868293801550163?s=43%22%3Ehttps://x.com/_pblanknews/status/2048868293801550163?s=43%3C/a https://x.com/designsage/status/2052725699010568239?s=43%22%3Ehttps://x.com/designsage/status/2052725699010568239?s=43%3C/a https://x.com/shadowofezra/status/2054036198662832596?s=43%22%3Ehttps://x.com/shadowofezra/status/2054036198662832596?s=43%3C/a https://x.com/younggun8140/status/2054679742410825837?s=43%22%3Ehttps://x.com/younggun8140/status/2054679742410825837?s=43%3C/a https://x.com/healthranger/status/2054597974454366369?s=43%22%3Ehttps://x.com/healthranger/status/2054597974454366369?s=43%3C/a https://x.com/iluminatibot/status/2053799839859966133?s=20 https://x.com/X22Report/status/2054712128532332913?s=20 https://x.com/BGatesIsaPyscho/status/2054465279283876198?s=20 https://x.com/FletchMatlock/status/2054389538391265635?s=20 https://x.com/NorthrnPrspectv/status/2054379619906715750?s=20 https://x.com/X22Report/status/2054547827804479523?s=20 https://x.com/beverleyturner/status/2054179571990233499?s=20 https://x.com/is_OwenLewis/status/2054375024954581419?s=20 https://x.com/kevin_inalberta/status/2054196329170284718?s=20 https://x.com/jaycurrie/status/2053877914375172535?s=20 https://x.com/ExposingEvil704/status/2053134318650663245?s=20 https://x.com/TWilsonOttawa/status/2053567552354181380?s=20 https://www.youtube.com/watch?v=FeIQmZ74K_M https://x.com/SatireSquadHQ/status/2053140417873686828?s=20 https://x.com/greg_scott84/status/2053065484736581693?s=20 https://x.com/MelissaLMRogers/status/2053232853303926840?s=20         Timestamps: 00:00 - Intro and episode overview 02:16 - Alberta court blocks secession vote over treaty rights 04:43 - Canadian legal reasoning on Indigenous consultation 08:36 - First nations' treaty impacts from Alberta's decision 10:01 - Canadian political landscape's reaction to secession 12:47 - Deep state plans and global migration realities 15:12 - New energy tech: Casimir force microchips 18:10 - UFO disclosure, Pentagon videos, and Eric Weinstein's insights 32:21 - Australian machete amnesty and violence crisis 40:41 - Kids' health initiatives and trans policies 54:01 - Deep state, secret societies, and global power dynamics 72:22 - Eric Weinstein on UFOs, physics, and disclosure delays 96:18 - Obama's hidden past & conspiracy theories about his origin 114:00 - International schemes: UN migration, NGOs, and global governance  

Nancy Guthrie Case: 100 Days Later | DNA Breakthroughs, FBI Tension & Sheriff Nanos Speaks 100 days after the disappearance and suspected abduction of Nancy Guthrie, investigators say they may finally be getting closer to solving the case. In this episode of Police Off The Cuff, retired NYPD detectives break down the newest developments including possible DNA breakthroughs, forensic genealogy, the FBI's growing involvement, and public statements from Sheriff Chris Nanos. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Is freedom overrated? In his new book, Inside the Box, David Epstein argues that constraints, limits and obstacles are what stimulate creativity, innovation, collaboration and personal contentment.