Podcasts about breakthroughs

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Best podcasts about breakthroughs

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Latest podcast episodes about breakthroughs

The LEO Family Fitness Podcast
Silence Is Where Breakthroughs Begin

The LEO Family Fitness Podcast

Play Episode Listen Later Nov 6, 2025 3:54 Transcription Available


Send us a textYou ask a powerful question, the room goes quiet, and your stomach tightens—should you jump in? We pull back the curtain on why that silent pause is often the most important moment in a coaching session and how to trust it instead of rushing to fill it. When a client doesn't answer right away, it isn't a dead end; it's the mind at work, reaching past automatic responses to find what's real.We share a clear, practical approach to holding space: breathe, relax your body, and invite the client to take their time. Rather than stacking more words, protect the quiet and watch for subtle cues that thinking is happening. You'll hear how this played out on a recent certification call when a coach, after a reflective pause, realized she'd been taking aligned actions but never gave herself credit. That single insight shifted her energy—and the whole room's—proving that silence can spark momentum, clarity, and confidence.Along the way, we unpack why coaches feel pressure to talk (awkwardness, fear of emptiness, a habit of fixing) and offer mindset shifts that move you from performance to presence. The best insights come from your client, not from you, and the pause is where they claim them. We close by teeing up the next breakthrough: stopping the fixer reflex and guiding discovery instead, so sessions become lighter, deeper, and far more impactful.If this resonated, follow the show, share it with a coach who needs this reminder, and leave a quick review telling us what changes when you trust the pause.Interested in elevating your coaching skills and accelerating your clients' growth? Become a Certified Life Coach!Join the waitlist:https://www.modernleadership.us/mastery

CHRISTIAN LIFE COACH COLLECTIVE- Change Your Life, Start a Coaching Business, Walk in Your Calling

STUCKNESS ISN'T FAILURE— When clients loop, defend, or go quiet, they're not resisting you—they're protecting themselves. Your job isn't to push; it's to stay calm and create safety until their system can settle and see again. Key Takeaways Stuckness often signals pain, not rebellion. Silence and curiosity regulate the moment better than pressure. Presence builds trust that allows insight to emerge naturally. Action Guide When a client gets stuck, wait five full breaths before speaking. Let the stillness do its work. Read the Life Coach Blog Become a Life Coach Join the Coaching FB Community —> HERE Find me @coachlauramalone on IG —> HERE Your 5 star review on Apple Podcasts means a ton✨

Connecting the Dots
Ask: Tap Into the Hidden Wisdom of People Around You for Unexpected Breakthroughs In Leadership and Life

Connecting the Dots

Play Episode Listen Later Nov 6, 2025 31:14


Jeff Wetzler has been on a quarter-century quest to transform learning opportunities and unlock human potential. Blending a unique set of leadership experiences in the fields of business and education, he's pursued this quest as an international management consultant to executives in Fortune 500 corporations, as Chief Learning Officer at Teach For America, and currently, as co-CEO of Transcend, a nationally recognized education innovation organization. Jeff earned a Doctorate in Adult Learning and Leadership from Columbia University and a Bachelor's in Psychology from Brown University. He is an Aspen Global Leadership Fellow and an Edmund Hillary Fellow. Jeff lives in New York with his wife, two children, and their puppy.Link to claim CME credit: https://www.surveymonkey.com/r/3DXCFW3CME credit is available for up to 3 years after the stated release dateContact CEOD@bmhcc.org if you have any questions about claiming credit.

RARECast
Transforming Real-Word Patient Data into Breakthroughs

RARECast

Play Episode Listen Later Nov 6, 2025 39:53


A recent report from the health research network and real-world data platform TriNetX argues that by aggregating electronic health records, billing claims, and registry data across hundreds of healthcare sites makes it possible to study rare diseases more efficiently. Doing so could enable access to enough patient data to conduct meaningful research, which is often impossible through traditional clinical trials. We spoke to Jeff Brown, chief scientific officer of TriNetX, about how real-world data can address common challenges in rare disease research, the hurdles that need to be addressed, and how advances in AI could revolutionize rare disease research by using this data to identify patients and unlock insights.

Build Your Remarkable Practice for Chiropractors
088 - How to Turn Progress Exams into Patient Breakthroughs

Build Your Remarkable Practice for Chiropractors

Play Episode Listen Later Nov 6, 2025 21:30


The best progress exams don't just measure change, they build belief. In this episode, Dr. Bobby and Dr. Lona reveal how preparation, clarity, and confidence transform mid-care check-ins from routine updates into powerful moments of retention.They unpack what happens when teams slow down long enough to truly compare scans, celebrate progress, and reset expectations. You'll learn how the right visuals, words, and tone help people see their healing story and stay committed for the long haul. From pre-shift prep to the simple analogies that make complex results make sense, this conversation shows how certainty from the doctor creates confidence in the patient every time.Key Highlights01:15 – Why attention is the new currency—and how movement, props, and pacing make your videos more watchable and memorable.02:45 – What world-class filmmakers teach us about storytelling and pattern breaks that also apply to patient education.04:10 – How shifting your identity from “technician” to “visionary” changes the way you lead and communicate.05:35 – Why most practices underestimate the power of progress exams—and how doing them well becomes the backbone of retention.07:15 – How to prepare before every progress report so you walk in certain, clear, and ready to connect.10:30 – How to re-anchor expectations using x-rays and scans to help patients see progress that might not yet feel visible.12:20 – The best way to talk about time, healing, and progress without losing patient confidence.14:15 – What to say when scans look “different” instead of “better”—and how to keep the focus on growth, not perfection.16:25 – How the “three-legged stool” of adjustments, habits, and exercises keeps people accountable and results consistent.18:50 – Why consistency across multiple doctors matters—and how to explain the “handwriting” analogy that keeps trust intact. Resources MentionedTo schedule a Strategy Session with Dr Lona: https://go.oncehub.com/DrLonaBuildPodcastTo schedule a Strategy Session with Dr Bobby: https://go.oncehub.com/DrBobbyBuildPodcastLearn more about the Remarkable CEO Podcast: https://theremarkablepractice.com/podcast

The Daily Scoop Podcast
OPM expects a ‘fully automated' federal retirement system in the next six months

The Daily Scoop Podcast

Play Episode Listen Later Nov 5, 2025 5:40


As the Office of Personnel Management makes progress toward a long-pursued goal to move the government's paper-based retirement system into the 21st century, its director said a “fully automated” process is about six months away. OPM Director Scott Kupor said in an interview with FedScoop: “That's not going to happen overnight.” But, Kupor said he believes the agency can get there within six months “for sure.” The human capital agency hit a milestone in May with the launch of its Online Retirement Application, operationalizing a yearslong development effort and marking the end of paper file submissions. Yet behind the scenes at OPM, there's still much work to do to bring about a truly automated process. Though the application submissions are now online, humans still currently check the information coming in to make sure they've been completed properly and manually key in information into a calculator in “a significant number of cases,” Kupor said. That introduces “a huge amount of delay in the system” and is something the agency is working to fix. The aim is to ultimately have a system where the retiree, human resources, and the payroll provider all submit their information online and route that package electronically — not to a person in the agency's retirement services division, but to a Digital File System that can fill in the application and do the calculations, Kupor said. Under that future process, he said, all individuals at OPM will be doing is reviewing and spot checking. The simple target of what OPM is trying to do with retirement services, Kupor said, is to go paperless “as quickly as possible.” The Department of Energy is refreshing its investment in five research centers focused on quantum information science after five years of operation. In a Tuesday announcement, DOE said it's putting up $625 million to keep all of the existing National Quantum Information Science Research Centers (QIS) going for up to five more years, matching the same investment that launched those centers in 2020. Darío Gil, DOE undersecretary for science, said in a written statement: “President Trump positioned America to lead the world in quantum science and technology and today, a new frontier of scientific discovery lies before us. Breakthroughs in QIS have the potential to revolutionize the ways we sense, communicate, and compute, sparking entirely new technologies and industries.” The centers were authorized by Congress and signed into law in 2018 during the first Trump administration as part of the National Quantum Initiative Act. Since the first January 2020 investment from DOE — which envisioned “two to five multidisciplinary Quantum Initiatives” — centers led by its Brookhaven, Argonne, Lawrence Berkeley, Oak Ridge, and Fermi National Laboratories have been established. According to a DOE press release, the work of each center includes supporting science that has “disruptive potential across quantum computing, simulation, networking, and sensing,” as well as establishing “community resources, workforce opportunities, and industry partnerships.” The Daily Scoop Podcast is available every Monday-Friday afternoon. If you want to hear more of the latest from Washington, subscribe to The Daily Scoop Podcast  on Apple Podcasts, Soundcloud, Spotify and YouTube.

Biotech 2050 Podcast
Foresite Capital's Jim Tananbaum on Biotech Cycles, AI Breakthroughs & Long-Term Value

Biotech 2050 Podcast

Play Episode Listen Later Nov 5, 2025 23:17


Synopsis: Jim Tananbaum, Founder & CEO of Foresite Capital, joins Rahul Chaturvedi to dissect the patterns driving biotech innovation, the role of macroeconomic cycles in venture performance, and how disciplined science fuels enduring investment success. Drawing from three decades across entrepreneurship and venture leadership, Jim reflects on his path from co-founding drug discovery startups with Harvard collaborators to building one of the most respected investment firms in life sciences. He unpacks how interest rate environments shape fund vintages, why AI is emerging as the next transformative platform, and how investors can identify enduring opportunities amid volatility. Their discussion spans valuation compression, AI-driven discovery, CNS and Alzheimer's innovation, and the geopolitical forces influencing biotech globally. Jim's perspective offers a masterclass in balancing scientific rigor with strategic foresight — and in positioning capital where breakthrough innovation meets sustainable impact. “Lean into areas where there's likely to be immense change,” Jim advises — a principle as relevant to biotech investing as it is to shaping the future of healthcare itself. Biography: Jim is the founder and CEO of Foresite Capital, a healthcare investment firm founded in 2011 that has approximately $3.5B in assets under management. Jim assembles the people, ideas, and money needed to launch products that save lives and improve healthcare. During the last three decades, Jim has been a thought partner for some of the fastest-growing companies of their generation, including 10x Genomics (Nasdaq: TXG), Amerigroup (Nasdaq: ANTM), and Jazz Pharmaceuticals (Nasdaq: JAZZ). Jim's entrepreneurial experience began at Harvard Business School when he co-founded GelTex Pharmaceuticals (Nasdaq:GENZ). With less than $80M in funding, GelTex brought two drugs to market, and the company was acquired in 1999 for $1.4B. Jim was also the founding chief executive of Theravance, Inc. Under his tenure, he raised over $350M. Theravance has since split into two parts, one of which is now part of GSK's respiratory franchise through a joint venture, Innoviva (Nasdaq: INVA), and the other was spun out into Theravance Biopharma, Inc. (Nasdaq: TBPH). Together, they achieved a market capitalization that exceeded $4B. Jim's investment experience includes co-founding Prospect Ventures and, earlier in his career, being a partner of Sierra Ventures, where he established its healthcare services investment practice. Jim graduated from Yale with a BS and BSEE in Applied Math and Electrical Engineering/Computer Science. He then earned an MD from Harvard, graduating from the Harvard/MIT HST Program. He also earned an MBA from Harvard while playing rugby.

Uncomfy: Sticking with Moments That Challenge Us
How One Citizen Got Congress to Work Together on Climate Change — Jay Butera and Sam Daley-Harris

Uncomfy: Sticking with Moments That Challenge Us

Play Episode Listen Later Nov 5, 2025 21:12


What does it really take to make your voice heard in Congress? In this episode, Host Julie Rose talks with Sam Daley-Harris, founder of RESULTS and Civic Courage, and Jay Butera, the citizen advocate who helped create the bipartisan Climate Solutions Caucus in Congress. Jay shares how he spent three years hearing “no” before finally convincing one Republican member of Congress to say “yes” to working across the aisle on climate change. Sam explains how transformational advocacy—showing up, building trust, and listening deeply—can turn ordinary citizens into powerful changemakers. Sam's book, Reclaiming Our Democracy: Every Citizen's Guide to Transformational Advocacy - https://reclaimingourdemocracy.com/ Get in touch with Sam – https://docs.google.com/forms/d/e/1FAIpQLSdCQuqj-4O2eh4Sfy_E-dfVntbPlqg1A4T4oQ8E2J0nuZbD-w/viewform Climate Solutions Caucus - https://climatesolutionscaucus-garbarino.house.gov/ Top of Mind episode on what to do if you're feeling unheard by Congress - https://www.byuradio.org/feeling-unheard-by-congress-heres-what-you-need-to-know Subscribe for more stories about growth, discomfort, and courage! CHAPTERS 00:00 Introduction 00:38 Meet Sam Daley-Harris and Jay Butera 01:14 The Birth of the Climate Solutions Caucus 02:07 Challenges and Breakthroughs in Advocacy 05:33 Building Relationships in Congress 08:09 The Turning Point: Congressman Curbelo's Involvement 12:06 Impact and Reflections on Advocacy 17:49 Final Thoughts and Encouragement

Authors on the Air Global Radio Network
Heather Hildenbrand: Fear, Beliefs, and Breakthroughs

Authors on the Air Global Radio Network

Play Episode Listen Later Nov 5, 2025 37:48


In this conversation, Heather Hildenbrand, an author and money and mindset coach, shares her journey from writing romance to becoming a coach specializing in manifestation and self-development. She discusses the importance of self-approval, overcoming fear, and the impact of beliefs on success. Heather offers tips on embracing imperfection and taking action to alleviate fear. The conversation also touches on the significance of understanding one's emotions and the power of self-discovery in personal growth. Chapters 00:00 Introduction to Heather Hildenbrand 01:04 Heather's Journey as an Author and Coach 03:24 The Power of Self-Development and Energy Work 06:19 Navigating Self-Approval and Vulnerability 07:44 The Importance of Self-Approval in Writing 11:30 Overcoming Fear and Taking Action 14:37 Creating Desired Feelings and Regulating Emotions 16:48 The Journey of Self-Discovery and Healing 17:34 Advice for New Writers and Authors 20:50 The Impact of Beliefs on Success 24:51 Celebrating Small Wins and Building Confidence 27:08 The Role of Fear in Our Lives 29:58 Embracing Imperfection and Self-Compassion 32:24 Breaking Down Limiting Beliefs Author's Website: www.manifestyourhea.com Social Media Links: https://www.instagram.com/manifestyourhea/ Author Bio: Heather Hildenbrand is a money & mindset coach for authors who are tired of feeling stuck and ready to manifest their own happily ever after. She helps her clients drop their limiting beliefs so they can step into who they really are and create the life of their dreams. She is a certified life coach, a Reiki master, and basically an obsessed expert for all things manifestation and mindset. Book Link: https://www.manifestyourhea.com/book Love this episode? Rate it ⭐️ Thumbs Up

Breakthroughs
Uncovering heart failure

Breakthroughs

Play Episode Listen Later Nov 5, 2025 34:56


In this episode our expert panel discuss the topic of heart failure, exploring what it is, symptoms to be aware of, diagnosis, and the impact it can have on daily life. Our host Dr Ellie Cannon is joined by Anna Tomlinson, CEO at Cardiomyopathy UK, and Seema Patel, Specialty Care Medical Director at Pfizer UK. PP-UNP-GBR-13584 / October 2025 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Authors on the Air Global Radio Network
Heather Hildenbrand: Fear, Beliefs, and Breakthroughs

Authors on the Air Global Radio Network

Play Episode Listen Later Nov 5, 2025 37:48


In this conversation, Heather Hildenbrand, an author and money and mindset coach, shares her journey from writing romance to becoming a coach specializing in manifestation and self-development. She discusses the importance of self-approval, overcoming fear, and the impact of beliefs on success. Heather offers tips on embracing imperfection and taking action to alleviate fear. The conversation also touches on the significance of understanding one's emotions and the power of self-discovery in personal growth. Chapters 00:00 Introduction to Heather Hildenbrand 01:04 Heather's Journey as an Author and Coach 03:24 The Power of Self-Development and Energy Work 06:19 Navigating Self-Approval and Vulnerability 07:44 The Importance of Self-Approval in Writing 11:30 Overcoming Fear and Taking Action 14:37 Creating Desired Feelings and Regulating Emotions 16:48 The Journey of Self-Discovery and Healing 17:34 Advice for New Writers and Authors 20:50 The Impact of Beliefs on Success 24:51 Celebrating Small Wins and Building Confidence 27:08 The Role of Fear in Our Lives 29:58 Embracing Imperfection and Self-Compassion 32:24 Breaking Down Limiting Beliefs Author's Website: www.manifestyourhea.com Social Media Links: https://www.instagram.com/manifestyourhea/ Author Bio: Heather Hildenbrand is a money & mindset coach for authors who are tired of feeling stuck and ready to manifest their own happily ever after. She helps her clients drop their limiting beliefs so they can step into who they really are and create the life of their dreams. She is a certified life coach, a Reiki master, and basically an obsessed expert for all things manifestation and mindset. Book Link: https://www.manifestyourhea.com/book Love this episode? Rate it ⭐️ Thumbs Up

Heart Doc VIP with Dr. Joel Kahn
Episode 466: Breakthroughs in Heart Valve Disease Treatment

Heart Doc VIP with Dr. Joel Kahn

Play Episode Listen Later Nov 4, 2025 28:56


This week on Heart Doc VIP, Dr. Joel Kahn reviews the latest advances in treating aortic and mitral valve disease. While prevention remains the cornerstone of heart health, not all valve conditions can be avoided — and many require medical or surgical intervention beyond lifestyle changes. Dr. Kahn brings you up to date on the newest valve therapies and what they mean for patients. Short topics this week include semaglutide's effects on the heart, the connection between gum disease and brain health, the media's role in shaping medical news, the healthiest antidote to sitting, stem cells for heart repair, the value of calcium scoring, and how fruits and vegetables can improve sleep.  Dr. Kahn also invites listeners to explore catchbio.com — the first cancer screening and prevention risk app. Use code DRKAHN to save 25% on the annual subscription. And don't miss out on high-quality EVOO from getfreshdrkahn.com — just $1 for shipping!

Hair of the Dog Podcast
When “Doing It Right” Still Fails

Hair of the Dog Podcast

Play Episode Listen Later Nov 4, 2025 34:10 Transcription Available


315 - You did it all right, the call flowed, you connected, you nailed the pricing talk, and then… nothing. In this episode, Heather and I unpack what to do when a client ghosts you even after your best effort, how to stay curious instead of crushed, and why “doing it right” doesn't guarantee a yes (and why that's actually a good thing).What to Listen For:Heather's 3 phases of the client journey and why phase 3 is the “Wait… what?!” momentThe truth about doing everything “right” and why that doesn't always equal bookedTwo mental tracks after a “no”: frustration spiral vs. curiosity and growthHow to set action goals you control, not outcome goals you can'tSmart follow-up strategies and why more than one is essentialWhy ghosting isn't always rejectionTurning marketing into something that's actually fun How to build resilience and self-trust through every “no”What to do when fear of failure stalls your next inquiry callDoing everything “right” doesn't promise a yes but it can teach you exactly what you need to grow. In this episode, learn how to shift from frustration to curiosity, follow up with confidence, and build resilience that leads to more bookings. Want hands-on coaching? Join us for Coach Week, Nov 11–13 at 2pm ET. It's totally free, with replays included.  Sign up here - https://www.freedomfocusformula.com/coachweekAdditional Links: Ep. 284 - Stop Inquiry Ghosting - https://www.freedomfocusformula.com/blog/stop-inquiry-ghostingNicole's Instagram: @nicolebegleyofficialHeather's Flourish Academy - https://flourishacademy.mykajabi.com/Master the craft of pet photography at the Hair of the Dog Academy – www.hairofthedogacademy.comFreedom Focus Formula – www.freedomfocusformula.comElevate – www.freedomfocusformula.com/elevateCommercial Pet Photography Academy – www.hairofthedogacademy.com/commercialJoin Us for Coach Week: 3 Days of Live Coaching and Breakthroughs to Help You Unlock Your Photography Business PotentialNovember 11th, 12th, 13th at 2 PM EST DailyJOIN THE PARTY: Connect with us on Instagram Explore valuable pet photography resources here Discover effective pricing and sales strategies for all portrait photographers. Ready to grow your business? Elevate helps you do just that. Check out our recommended gear and favorite books.

Hacking Your Health
Ozempic/GLP-1 Breakthroughs, Sleep Wins, VBT Strength Beat 1RM, Fiber Fix for Longevity

Hacking Your Health

Play Episode Listen Later Nov 4, 2025 41:56 Transcription Available


In this episode, Ben and Dave discuss various topics related to health, fitness, and personal anecdotes. They explore the importance of sleep, the role of motivation and accountability in workouts, and the innovations in health technology, including wearables and GLP-1 medications. The conversation also touches on the significance of fiber as a staple supplement and the mind-body connection in achieving fitness goals.TakeawaysAI can't fix microphone problems.DHA and Pregnalone can optimize testosterone therapy.The global biohacking market is projected to grow significantly.Sleep is crucial for recovery and productivity.Gamification can enhance workout motivation.Velocity-based training is more effective than one rep max.Fiber is essential for overall health and should be a staple supplement.GLP-1 medications can help reduce cravings for substances.Thinking about workouts can enhance strength gains.Positive thinking can lead to better health outcomes.Support the showCheck out Overclock and Protein Protocol hereWant to know more about coaching? Book a call with Ben here Where to find usWe Hack Health: TwitterWe Hack Health: InstagramWe Hack Health: Discord

Shorts with Tara and Jill
Midlife: Boobs, Boundaries & Breakthroughs with Dawn Davis

Shorts with Tara and Jill

Play Episode Listen Later Nov 4, 2025 16:12


Dawn Davis returns to explain the origins and purpose of the Ember Circle, a space for midlife women to deeply connect and support each other through transitions such as empty nesting and identity shifts. The conversation touches on the concept of holding space for oneself and nurturing one's own life beyond prescribed roles. They explore the impact of anticipatory grief on women and emphasize the importance of community and self-care. Dawn also shares insights into her book, 'Mama, As You Are,' which aims to support mothers in navigating guilt and embracing 'good enough' parenting. Topics 00:47 Meet Our Guest: Dawn Davis 01:16 The Concept of Ember Circle 02:25 Navigating Midlife Transitions 05:01 Creating Sacred Spaces for Women 06:52 The Power of Connection and Trust 10:13 Dawn Davis' Book: Mama's You Are 11:19 Embracing Imperfection and Guilt 15:29 Conclusion and Final Thoughts

Happy Mama Movement with Amy Taylor-Kabbaz
# 318 | BREAKDOWNS LEAD TO BREAKTHROUGHS | WITH MANDY JACKSON

Happy Mama Movement with Amy Taylor-Kabbaz

Play Episode Listen Later Nov 4, 2025 32:48


Welcome back, Mama's.This week, Amanda Jackson and I explore the profound journey of motherhood and Matrescence, discussing the emotional and physical transformations that come with becoming a mother. We delve into the struggles of adjusting to new identities, the importance of self-care, and the need to listen to one's body. Amanda shares her personal experiences and insights from her book, emphasizing the significance of community support and the healing power of sharing stories among mothers.Some takeaways from our conversation:Writing a book is a vulnerable process.Matrescence is often unrecognized in motherhood.Motherhood can challenge our expectations and identities.Breakdowns can lead to breakthroughs in self-awareness.Listening to our bodies is crucial for well-being.Self-care should be about tuning into our needs.Creating support systems is essential for mothers.The experience of motherhood is shared across generations.Healing comes from sharing our stories.Empowerment in motherhood comes from understanding matrescence.About MandyAmanda, or Mandy as she's affectionately known by her clients, guides mothers on a pathfrom guilt to growth. Her methods make visible the invisible loads and expectations that setmothers up to feel as though they've failed.Instead of perpetuating myths that the role of mother will neatly integrate into life withoutchanging us, Mandy #39;s signature programs embrace matrescence and the mother-childrelationship as opportunities for profound personal and professional growth.Mandy has a background in psychology and sociology and completed her thesis on theregulation of pregnant women's bodies. Her approach draws from experience in CorrectiveServices, youth and family development, and corporate sectors.Chapters00:00 The Birth of a Book02:16 Honoring the Body in Motherhood05:47 The Reality of Matrescence11:31 Breakdowns and Breakthroughs18:34 Redefining Self-Care23:50 Creating Accessible Support for Mothers28:07 Reflections on Matrescence and Self-Connection Hosted on Acast. See acast.com/privacy for more information.

Pharma and BioTech Daily
**Industry Shifts: Mergers, Regulations, and Biotech Breakthroughs**

Pharma and BioTech Daily

Play Episode Listen Later Nov 4, 2025 8:20


Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a series of transformative events reshaping the landscape of healthcare, from strategic mergers and regulatory shifts to groundbreaking advancements in drug development.Let's begin with a monumental merger that signals a shift towards more integrated healthcare solutions. The $48.7 billion acquisition of Kenvue, a consumer health spinout from Johnson & Johnson, by Kimberly-Clark illustrates the growing convergence between consumer health products and traditional pharmaceuticals. This strategic move highlights a trend towards expanding product portfolios and enhancing distribution networks, aiming to better address comprehensive patient needs. Mergers like these could redefine how healthcare products are marketed and delivered, emphasizing holistic approaches to patient care.Turning to regulatory news, the resignation of Dr. George Tidmarsh from the FDA due to controversial communications has spotlighted the ongoing challenges within regulatory oversight. This incident underscores the delicate balance regulators must maintain in ensuring transparency while safeguarding sensitive information. Such developments are crucial as they directly affect public trust in drug approval processes and the industry's ability to navigate complex regulatory landscapes.In scientific advancements, Roche is making significant progress with its drug Gazyva for autoimmune diseases. Following FDA approval for lupus-related kidney disease, promising Phase 3 trial results for systemic lupus erythematosus (SLE) are propelling Roche closer to offering new hope for patients with this chronic condition, which currently has limited effective treatments. This success underscores the potential of targeted therapies in transforming treatment paradigms for autoimmune diseases.Eli Lilly's $3 billion investment in a new manufacturing facility in the Netherlands marks a strategic effort to bolster oral medicine production globally. This expansion not only reinforces Lilly's commitment to meeting global demand but also reflects an industry-wide trend towards investing in scalable manufacturing capabilities. Such moves are critical for ensuring supply chain resilience and addressing rising healthcare needs worldwide.In legal news, Pfizer's fierce competition with Metsera over Novo Nordisk's counteroffer highlights the high stakes involved in securing promising assets within the biotech sector—a sector particularly focused on obesity treatment due to its substantial market growth potential. The outcome of this legal battle could influence future strategic partnerships and acquisitions, demonstrating the intense competition among pharmaceutical giants.Meanwhile, UniQure faces challenges as its gene therapy for Huntington's disease encounters regulatory hurdles with the FDA. Despite initial expectations as a groundbreaking treatment, this setback emphasizes the rigorous scrutiny gene therapies undergo to ensure safety and efficacy. Such hurdles highlight the complexities of advancing novel therapies through regulatory pathways.Policy developments are also reshaping drug pricing structures as evidenced by HRSA's approval of eight drugmakers' plans for a 340B rebate model pilot program. This initiative aims at optimizing pricing structures while balancing cost containment with access to essential medications for underserved populations—a critical concern in today's healthcare landscape.International collaborations continue to play a pivotal role in accelerating drug discovery and development. Neurocrine Biosciences' $880 million deal with China's TransThera Sciences exemplifies such partnerships, focusing on emerging therapeutic areas like immunology. These collaborations are vital in leveraging global expertise and resources to drive innovatSupport the show

Babe Philosophy
Is a breakup the best thing for my relationship? with Bryan Power

Babe Philosophy

Play Episode Listen Later Nov 4, 2025 51:36


DOWNLOAD "THE POWER OF TOO MUCH," our FREE modern-day grimoire that helps you reclaim your intensity, your magic, and your voice: https://babephilosophy.com

The Nugget Climbing Podcast
EP 286: Steve Moss — Why Discomfort Fuels Breakthroughs, Double V12 Days at Age 40, and 455 V-Points in 24 Hours

The Nugget Climbing Podcast

Play Episode Listen Later Nov 3, 2025 167:25


Steve Moss is a high-level boulderer and the co-founder of a brewery and pizzeria in Spokane, WA. We talked about finding climbing at age 24, his breakthrough season climbing three V12s in less than two weeks at age 40, why discomfort helps us grow, his training routine for the past year, building a successful brewery and pizzeria from the ground up, what matters most in climbing, gratitude for life, the connections we make through climbing, and much more.The Nugget Training App | 14 Day Free Trialtraining.thenuggetclimbing.comThe GRINDS Program | FREE Finger Training PDFthenuggetclimbing.com/grindsThe NUG | Portable Hangboardfrictitiousclimbing.com/products/the-nugRúngne (Chalk & Apparel)rungne.info/nuggetUse code “NUGGET" for 10% off and "SHIPPINGNUGGETS" for free shipping.Mad Rock (Shoes & Crash Pads)madrock.comUse code “NUGGET10” at checkout for 10% off your next order.Become a Patron:patreon.com/thenuggetclimbingShow Notes:  thenuggetclimbing.com/episodes/steve-mossNuggets:(00:00:00) – Intro(00:02:21) – Steve's climbing origin story(00:07:30) – Life before climbing(00:09:58) – His wife(00:14:27) – Leavenworth(00:18:41) – A resurgence of stoke(00:23:37) – Passion & challenge(00:26:36) – Why discomfort is beneficial(00:34:21) – Building the brewery(00:52:31) – Brewing beer(00:56:56) – Steve's nephew(01:04:11) – Double V12 day(01:11:46) – Gratitude(01:14:37) – Protein & breakthroughs(01:20:51) – Bodyweight(01:24:17) – Crimping(01:27:42) – The hardest part of training(01:36:39) – Steve's training(02:03:30) – 455 V-point day(02:20:31) – Century bike ride(02:21:49) – Advice for a young Steve Moss(02:27:48) – Baseball(02:29:19) – The people(02:36:21) – What's next

The Plus SideZ: Cracking the Obesity Code
GLP-1 Wars: Obesity Week Highlights, Novo Nordisk vs. Pfizer, and Addiction Breakthroughs

The Plus SideZ: Cracking the Obesity Code

Play Episode Listen Later Nov 3, 2025 89:23


Resources for the Community:___________________________________________________________________https://linktr.ee/theplussidezpodcast Ro - Telehealth for GLP1 weight management https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55Find Your US Representatives https://www.usa.gov/elected-officials ______________________________________________________________________Get the latest buzz on GLP-1 therapies and the future of metabolic medicine! This episode provides an in-depth look at what's coming out of Obesity Week in Atlanta, GA, featuring expert insights from Dave Knapp from On the Pen.Key Topics & Breakthroughs:Corporate Battle for Biotech: We break down the surprise counteroffer by Novo Nordisk to acquire Metsera, the obesity biotech company that Pfizer had recently announced it was buying, setting the stage for a major pharmaceutical turf war.Pipeline Watch: Dive into the plethora of new therapies in current clinical trials, including the latest developments from Viking Therapeutics and the push for Oral GLP-1s.GLP-1's New Frontier: Discover the groundbreaking research on GLP-1's potential role in treating alcohol and narcotics addictions. We also discuss Brenipatide and its surprising dual focus on alcohol abuse and asthma.Tune in for a comprehensive review of the medications, mergers, and clinical trials shaping the next generation of weight loss and metabolic treatments.______________________________________________________________________⭐️Mounjaro Stanley⭐️griffintumblerco.Etsy.comUse code PODCAST10 for $ OFF______________________________________________________________________Join this channel to get access to perks:   / @theplussidez______________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide  #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1StoriesSend us Fan Mail! GetClaimable.com/PlusSideZ to appeal your GLP-1 Insurance Denails and use code PlusSideZ to save! Support the showKim Carlos, Executive Producer TikTok https://www.tiktok.com/@dmfkim?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/dmfkimonmounjaro?igsh=aDF6dnlmbHBoYmJn&utm_source=qr Kat Carter, Associate Producer TikTok https://www.tiktok.com/@katcarter7?is_from_webapp=1&sender_device=pc Instagram https://www.instagram.com/mrskatcarter?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==

Egg Meets Sperm
Root Causes of Infertility: Silent Infections, Hidden Toxins & Advanced Testing for Fertility Breakthroughs with Dr Natalie Underberg

Egg Meets Sperm

Play Episode Listen Later Nov 3, 2025 37:19


Infertility isn't always about age or hormones—sometimes the real culprits are hidden, silent root causes that standard medicine rarely investigates. In this powerful conversation, we explore the cutting-edge research and clinical insights that are changing the way we understand fertility struggles and recurrent pregnancy loss.Joining me on this episode is Dr. Natalie Underberg, a leading voice in functional medicine, women's health, and fertility. She runs her own private practice, and she is also the founder of FIG Wellness, a faith-based supplement company known for its science-backed formulations and their leading HIS&HERS prenatal vitamins — world-class products that feature industry-leading doses of crucial nutrients like 900 mg of choline, setting a new standard in perinatal nutrition and were formulated specifically by Dr. Natalie and her husban,d Dr. Jake.Dr. Natalie has helped hundreds of couples achieve natural pregnancies by uncovering and addressing the root causes of hormonal imbalances, PCOS, gut dysfunction, and recurrent pregnancy loss. She is also the creator of The PCOS Collective and The Pregnancy Prep Academy — educational programs designed to empower women to take control of their health and fertility with personalized, root-cause care.Her work blends clinical expertise, real-life experience, and faith-centered guidance to support couples in stewarding their health and fertility naturally, without unnecessary medications or fertility procedures.

Beauty in Behavior
260. The Name That Found Me

Beauty in Behavior

Play Episode Listen Later Nov 3, 2025 17:18


Welcome to a brand-new chapter — and the very first episode under the new name:Chaos to Connection: Boundaries & Breakthroughs for Cycle-Breaking Women.In this episode, I share the story behind how this name found me — not as a marketing move, but as a reflection of my own becoming.The journey began years ago with Beauty in Behavior, back when I was still teaching. It was there that I discovered that the most challenging behaviors — whether from my students or my own children — were actually invitations to grow. These moments became my greatest teachers, shaping how I saw children, and eventually, how I saw myself.When the podcast evolved into Beautiful Behavior, it mirroredanother layer of my growth — the one where I began noticing my own people-pleasing patterns, the ways I silenced myself to keep the peace, and how often I deferred to others instead of trusting my own wisdom.And now, Chaos to Connection feels like the name that truly chose me — the story of my life, really. A journey that began in chaos and continues to unfold toward deeper connection, authenticity, and truth.From the outside, not much has changed — but the energy underneath it all has. And that changes everything.This episode is an invitation to grow together — to walk the path from chaos to connection, one courageous step at a time.Reflection question:Where in your life are you being invited to move from chaos to connection?Connectwith Diane:Instagram: @dianesorensen.bbFacebook: https://www.facebook.com/diane.sorensen.589Join the conversation — share your takeaways or questions from today's episode by sending me a message onInstagram or Facebook. I love hearing from you!Work with Diane:Diane Sorensen's Coaching Programs are where boundarywork becomes the bridge from chaos to connection.You'll learn to transform your triggers, lead with compassion, and create emotionally safe relationships built on authenticity, not approval.Reclaim your CALM, speak your TRUTH, and live FREE.→ Submit an inquiry or learn more:www.dianesorensen.net/contact→ Explore free guides and resources to support your growth: www.dianesorensen.net/ → Join the weekly newsletter for insights, tools, and support delivered straight to your inbox: www.dianesorensen.net/email-list      

Pharma and BioTech Daily
Precision Oncology and HIV Prevention Breakthroughs

Pharma and BioTech Daily

Play Episode Listen Later Nov 3, 2025 7:18


Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into a series of fascinating advancements and strategic movements that are shaping the landscape of drug development and patient care.Starting with a significant milestone in precision oncology, China has approved its first EGFR-targeted antibody-drug conjugate. This approval marks a pivotal moment in the industry's shift towards targeted therapies, which promise more precise treatment options with potentially fewer side effects than traditional chemotherapy. Targeted therapies are at the forefront of personalized medicine, where treatments are tailored to individual genetic profiles, offering hope for more effective cancer care.In the realm of HIV prevention, Gilead Sciences has reported impressive sales for its new long-acting pre-exposure prophylaxis medication, Yetztugo. Since its launch in June 2025, Yetztugo has generated $54 million in U.S. sales, underscoring the demand for long-term HIV prevention solutions. This development is part of Gilead's broader strategy to strengthen its HIV franchise as it advances its pipeline with promising candidates like GS-3242 alongside lenacapavir. The aim is to develop treatments that require less frequent dosing, which could significantly improve patient adherence and outcomes. Despite challenges within its HIV portfolio and declining Veklury sales, Gilead Sciences is actively seeking growth opportunities through strategic partnerships and pipeline advancements—an essential approach for navigating patent cliffs while sustaining long-term growth.On the financial front, AbbVie has increased its revenue forecast by $400 million to a staggering $60.9 billion, driven by robust sales from its immunology drugs Skyrizi and Rinvoq. These treatments address chronic inflammatory conditions like psoriasis and rheumatoid arthritis, reflecting AbbVie's strong positioning in this therapeutic area despite competitive pressures. AbbVie continues to report strong earnings from Skyrizi and Rinvoq, reinforcing its dominance in the immunology market and highlighting the profitable nature of successful biologics in treating chronic inflammatory diseases.Biogen continues to bolster its multiple sclerosis franchise by focusing on both legacy treatments and new product launches. This strategy highlights the importance of balancing innovation with lifecycle management to maintain market strength against generic competition—a common challenge in the industry.Meanwhile, the American Academy of Pediatrics has taken a cautious stance by not endorsing leucovorin for autism treatment due to insufficient evidence. This decision emphasizes the critical need for rigorous, evidence-based practices in developing clinical guidelines for complex disorders like autism.Internationally, CSL Seqirus has partnered with Saudi Arabia to supply cell-based influenza vaccines and support local production capabilities. This move aligns with global efforts to enhance pandemic preparedness and healthcare resilience through local manufacturing initiatives.The volatile nature of the biotech sector is evident with reports of 16 companies ceasing operations in 2025 due to high R&D costs and regulatory challenges. Despite these closures, such volatility opens doors for new innovations that could address unmet medical needs.Turning our attention to obesity treatment, Eli Lilly stands at a crucial juncture with its novel obesity medication, orforglipron. The company aims to make this weight loss pill accessible while maintaining financial viability for future R&D—a balancing act faced by many pharmaceutical companies as they strive to deliver affordable yet innovative treatments amid growing global health concerns. However, not all R&D efforts reach fruition. Eli Lilly has decided to discontinue its mid-stage program Support the show

Living Astrology With Janet Hickox
From Purpose to Possibility — A Soul Blueprint Week of Breakthroughs

Living Astrology With Janet Hickox

Play Episode Listen Later Nov 3, 2025 61:42


Fluent Fiction - Dutch
From Canvas to Critics: A Night of Art and Breakthroughs

Fluent Fiction - Dutch

Play Episode Listen Later Nov 2, 2025 17:29 Transcription Available


Fluent Fiction - Dutch: From Canvas to Critics: A Night of Art and Breakthroughs Find the full episode transcript, vocabulary words, and more:fluentfiction.com/nl/episode/2025-11-02-08-38-20-nl Story Transcript:Nl: De lucht was grijs boven Amsterdam, bladeren dwarrelden naar beneden in de koele bries van de herfst.En: The sky was gray above Amsterdam, leaves swirling down in the cool autumn breeze.Nl: Binnen in het Van Gogh Museum hing een warme sfeer, met zachte lampen die de kunstwerken verlichtten.En: Inside the Van Gogh Museum hung a warm atmosphere, with soft lights illuminating the artworks.Nl: Het was de avond van een belangrijke evenement: de lancering van een nieuwe kunsttentoonstelling.En: It was the evening of an important event: the launch of a new art exhibition.Nl: Sander stond bij de ingang.En: Sander stood by the entrance.Nl: Zijn ogen glansden van opwinding.En: His eyes gleamed with excitement.Nl: Hij werkte maanden aan deze tentoonstelling en dit zou zijn grote doorbraak kunnen zijn.En: He had been working on this exhibition for months, and this could be his big breakthrough.Nl: Hij keek uit naar het succes van deze avond.En: He looked forward to the success of this evening.Nl: De reputatie van het museum en zijn carrière stonden op het spel.En: The museum's reputation and his career were at stake.Nl: Aan de andere kant van de zaal stond Maarten.En: On the other side of the hall stood Maarten.Nl: Hij was nerveus, zijn handen zweeterig.En: He was nervous, his hands sweaty.Nl: Zijn werk hing hier, voor het eerst in zo'n prestigieuze ruimte.En: His work was displayed here for the first time in such a prestigious venue.Nl: De schilderijen vertelden verhalen die diep persoonlijk waren.En: The paintings told stories that were deeply personal.Nl: Toch twijfelde hij of de bezoekers zijn visie zouden begrijpen.En: Yet he doubted whether the visitors would understand his vision.Nl: Enkele gasten kwamen binnendruppelen.En: A few guests began to trickle in.Nl: Onder hen was Anouk, de beroemde kunstcriticus.En: Among them was Anouk, the famous art critic.Nl: Ze was streng en nieuwsgierig, altijd op zoek naar de waarheid in kunstwerken.En: She was strict and curious, always looking for the truth in artworks.Nl: De laatste tijd had ze nieuwkomers genadeloos beoordeeld, en dat maakte zowel Sander als Maarten nerveus.En: Lately, she had been reviewing newcomers mercilessly, and that made both Sander and Maarten nervous.Nl: "Sander," zei Anouk, haar ogen speurend langs de schilderijen.En: "Sander," said Anouk, her eyes scanning the paintings.Nl: "Wil je me rondleiden?"En: "Would you like to give me a tour?"Nl: "Zeker," antwoordde Sander, zijn stem vastberaden.En: "Certainly," Sander replied, his voice determined.Nl: "Ik wil je graag Maartens werk laten zien."En: "I would love to show you Maarten's work."Nl: Ze liepen samen door de tentoonstelling.En: They walked through the exhibition together.Nl: Sander vertelde gepassioneerd over Maartens inspiratie en technieken.En: Sander spoke passionately about Maarten's inspiration and techniques.Nl: Hij hoopte dat zijn uitleg Anouk zou overtuigen.En: He hoped that his explanation would convince Anouk.Nl: Toen ze bij Maartens centrale stuk kwamen, bleef Anouk staan.En: When they reached Maarten's central piece, Anouk paused.Nl: Ze raakte de delicate balans tussen chaos en orde aan.En: She touched on the delicate balance between chaos and order.Nl: "Interessant," zei ze peinzend.En: "Interesting," she said pensively.Nl: "Ik vraag me af of de intentie helder genoeg is."En: "I wonder if the intention is clear enough."Nl: Maarten had alles gehoord.En: Maarten had heard everything.Nl: Zijn hart bonsde in zijn borst.En: His heart was pounding in his chest.Nl: Hier was zijn kans.En: Here was his chance.Nl: Hij stapte naar voren.En: He stepped forward.Nl: "Mevrouw Anouk," begon hij voorzichtig, "ik wil graag uitleggen wat ik bedoelde."En: "Ms. Anouk," he began cautiously, "I would like to explain what I meant."Nl: Anouk keek hem aan, nieuwsgierig.En: Anouk looked at him, curious.Nl: Maarten vertelde over zijn strijd en emoties achter het schilderij.En: Maarten spoke about his struggles and the emotions behind the painting.Nl: Zijn stem kreeg meer kracht terwijl hij sprak.En: His voice gained strength as he spoke.Nl: Zijn ogen glansden van trots en passie.En: His eyes gleamed with pride and passion.Nl: Toen hij klaar was, glimlachte Anouk.En: When he finished, Anouk smiled.Nl: "Ik moet zeggen, Maarten, je passie is opmerkelijk.En: "I must say, Maarten, your passion is remarkable.Nl: Het geeft diepte aan je werk.En: It adds depth to your work.Nl: Dank je voor deze uitleg."En: Thank you for this explanation."Nl: De avond kwam ten einde en er klonk applaus door de zaal.En: The evening came to an end with applause filling the hall.Nl: Anouks recensie de volgende dag was verrassend positief.En: Anouk's review the next day was surprisingly positive.Nl: Ze noemde de tentoonstelling verfrissend en vol potentieel.En: She called the exhibition refreshing and full of potential.Nl: Zowel Maarten als Sander voelden een golf van opluchting en vreugde.En: Both Maarten and Sander felt a wave of relief and joy.Nl: Maarten was nu zekerder van zijn talent.En: Maarten now felt more confident in his talent.Nl: Sander leerde dat verhalen vertellen en persoonlijke engagement net zo belangrijk waren als de kunst zelf.En: Sander learned that storytelling and personal engagement were just as important as the art itself.Nl: De koude herfstavonden buiten konden hun vreugde niet temperen.En: The cold autumn evenings outside could not temper their joy.Nl: Hun toekomst in de kunstwereld zou zeker helder zijn.En: Their future in the art world would certainly be bright. Vocabulary Words:gray: grijsswirling: dwarreldenlaunch: lanceringevent: evenementexhibition: tentoonstellingentrance: inganggleamed: glansdenbreakthrough: doorbraakprestigious: prestigieuzevisitors: bezoekerstrickle: binnendruppelencritic: criticusstrict: strengmercilessly: genadeloosdetermined: vastberadenpassionately: gepassioneerdinspiration: inspiratietechniques: techniekendelicate: delicatebalance: balanschaos: chaosorder: ordepound: bondencautiously: voorzichtigcurious: nieuwsgierigemotions: emotiesstrength: krachtpride: trotsapplause: applausrefreshing: verfrissend

Finding Genius Podcast
Brain Science Breakthroughs Translating Neuroscience Into Mental Health Treatments

Finding Genius Podcast

Play Episode Listen Later Oct 31, 2025 19:55


Join us in this episode as Dr. Daniela Tropea, Associate Professor of Molecular Psychiatry at Trinity College Dublin, explains how cutting-edge brain research is being transformed into real-world treatments for mental health and neurodevelopmental disorders. Dr. Tropea leads the Translational Neuroscience Laboratory at Trinity, where her research on growth factors and brain plasticity has reshaped our understanding of brain health. Her work on insulin-like growth factor 1 directly contributed to the development of Trofinetide — the first FDA-approved treatment for Rett Syndrome. As she works, she continues to inspire new therapies for conditions like Fragile X and Phelan-McDermid Syndromes… This discussion dives into: How neuroscience research impacts real medical treatments. The future of translational neuroscience and personalized mental health care. Why mentorship, diversity, and public outreach are vital for scientific progress. A renowned educator and global collaborator, Dr. Tropea has received multiple awards for innovation in teaching and mentorship, and is deeply committed to making science accessible. Want to learn more about her intriguing work? Visit her profile at Trinity College Dublin or follow her latest publications in neuroscience.

Authentic Business Adventures Podcast
How to Make a Living With Your Art

Authentic Business Adventures Podcast

Play Episode Listen Later Oct 31, 2025


Tim Packer  - Tim Packer Art Academy On the Truth: "I mean the universities and colleges are failing them just miserably." We all remember being kids and making art of some kind.  Water colors, macaroni pictures, maybe even some Play-Doh creatures.  But did you ever think you could make a living from it?  Tim Packer realized he could. In this candid conversation, Tim Packer pulls back the curtain on the realities of the art world, busting myths about the "starving artist" and explaining why most universities and mainstream art advice miss the mark for artists hoping to make a living from their passion. He details how he leveraged both his artistic talent and business savvy to grow his own career, how he turned his mentorship of a young artist into a global success story, and how his experiences inspired him to launch his online academy to help others achieve the same. Listen as Tim explains how to enjoy what you do and make some good money doing it. Enjoy! Visit Tim at: https://www.timpackerartacademy.com/ On Instagram: https://www.instagram.com/timpackerartacademy/   Podcast Overview: 00:00 Teaching Artists to Earn Income 07:56 "Regret, Art, and Helping Others" 12:25 Art Worlds: Villages and Markets 16:39 90s Limited Edition Print Boom 22:11 "Keys to Successful Art Sales" 30:03 "From Artist to Police Officer" 35:30 "Art, Auctions, and Breakthroughs" 39:44 "Keys to a Thriving Art Career" 43:29 "Creating Art You Truly Love" 52:39 "When to Pursue Art Full-Time" 54:13 "Turning Point in Career Success" 01:03:10 Artistic Process and Experimentation 01:04:04 Breaking Free from Comfort Zones 01:11:18 "Art, Critics, and Accessibility" 01:15:44 Art vs Commerce Priorities Podcast Transcription: Tim Packer [00:00:00]: I mean, my dream when I. Because I quit my job and walked away from my pension as a police officer when I was 40 to give this another try. My goal was if I could ever just make as much as what I would have made had I stayed and gone on pension, then it'll be a wash, right? Well, I far surpass that. But while I was in there, you know, just kind of and watching the sales go up and I was mentally crunching the numbers because this was November, and I thought, holy. Know what? I'm going to make over a quarter million dollars this year. As an artist. James Kademan [00:00:34]: You have found Authentic Business Adventures, the business program that brings you the struggle stories and triumphant successes of business owners across the land. Downloadable audio episodes can be found in the podcast link fund@drawincustomers.com we are locally underwritten by the bank of Sun Prairie Calls On Call, Extraordinary Answering Service, as well as the Bold Business Book. And today we're welcoming preparing to learn from Tim Packer of Tim Packer Art Academy. I'm excited we get to talk about art, Tim. So how are you feeling today, Tim? Tim Packer [00:01:04]: I'm feeling great. I'm excited to be here and thanks for having me on the podcast. James Kademan [00:01:08]: Yeah, I'm excited because I don't know if you know this or not, but I majored in graphic design. Tim Packer [00:01:13]: Oh, me too. James Kademan [00:01:14]: Way back when. I don't do anything with it now. And I just got back from Italy and it was interesting because I'm like, wait a second, I've actually painted and drawn this cathedral. Tim Packer [00:01:27]: Yeah. James Kademan [00:01:28]: And I just never knew where it was. Tim Packer [00:01:30]: Oh, this is going to be a lot of fun then, because there's going to be a lot of context on your end, and I'm sure you're going to have a lot of questions as well, which is cool. Yeah. James Kademan [00:01:37]: So let's start with the foundation. What is Tim Packer Art Academy? Tim Packer [00:01:41]: Okay. It's my online art academy. And there's a lot of, like, recorded courses where people pay just for a certain course.

Hashtag Trending
AI Breakthroughs: OpenAI's Ambitious Future, Google's Revolutionary Algorithms, and SpaceX's Satellite Phones

Hashtag Trending

Play Episode Listen Later Oct 31, 2025 7:39


In this episode of Hashtag Trending, host Jim Love discusses groundbreaking advancements in AI and technology. OpenAI plans to develop an AI researcher by 2028 capable of scientific discoveries, alongside predictions of superintelligence within 10 years. Google DeepMind's Disco RL creates a powerful, self-learning algorithm, and the new Gemini for Home showcases an advanced voice assistant. Meanwhile, Elon Musk's SpaceX ventures into telecom with satellite phones aiming to provide global connectivity. The episode delves into the implications of these innovations for the future of AI and global technology. 00:00 Introduction and Overview 00:29 OpenAI's Ambitious Roadmap 02:12 Google DeepMind's Breakthrough 03:32 Google Gemini: The Future of Home AI 04:29 Elon Musk's Satellite Phone Revolution 05:59 The Bigger Picture: Self-Learning AI 07:04 Conclusion and Sign-Off

The Strength Running Podcast
Atlantic CEO Nick Thompson on Master's Training, Motivation, and Breakthroughs

The Strength Running Podcast

Play Episode Listen Later Oct 30, 2025 52:41


Nick Thompson has been running and racing for 35 years. He's the 40-44 age group American record holder in the 50k with a 3:04 finish time (that's 5:56 per mile for 31 miles), and was previously the world's top ranked runner in his age group in the 50-mile. He's now the CEO of the Atlantic Magazine and his new book is now available: The Running Ground: A Father, a Son, and the Simplest of Sports. You'll hear: How Nick's relationship with his father helped him get into running What drives him to compete today vs. 30 years ago His recommendations for passing along a love for running to your kids How his cancer diagnosis changed his relationship with running The training changes he made to finally have a breakthrough as a Master's runner Resources from the show: Follow Nick on Instagram Coaching Call: Make a Comeback at 40 Subscribe to The Atlantic Strength training for runners Thank you MOBO Board! Invented by renowned physical therapist Jay Dicharry, MOBO helps you stabilize your stance with an innovative rocker board that's set up on two fins. The design effectively forces you to drive your big toe into the board to improve your stability. I was pretty arrogant going into my first session on the MOBO Board. How hard can it be to balance, right? Well, I was humbled pretty quickly! Even if you're a good runner, better balance, stability, and proprioception is going to help you have a more powerful stride and prevent more running injuries. You'll learn how to improve the efficiency of the kinetic chain from your hip to your big toe. Because as Jay likes to say, it's not just how strong you are, but how well you use that strength. I was recently at a weekend physical therapy workshop (lol I was the only running coach) and learned how important (and rare) this simple movement is. Save 10% with code STRENGTHRUN10 at checkout at moboboard.com. Thanks to The Performance Training Journal! The Performance Training Journal is now available on Amazon and debuted as the #4 new release in the running category. Since I started running in 1998, I've kept a hardcopy training journal. Holding a tangible log, writing in it daily, and reflecting on the ups and downs of running is a surefire way to improve. This hardcopy training journal helps you focus on the training metrics that matter, prioritizes a long-term outlook so you don't take any shortcuts, and maintains your motivation with strategic self-praise. With a no-frills, functional design, the Performance Training Journal includes coaching advice on racing, injury prevention, strength training, and more. It will guide you through race scheduling, how to plan your race morning, the best workouts for endurance runners, and encourage you to track your personal bests over time. You have the space to make this journal your own whether you're a new runner or a professional, a trail or road runner, or a mid-distance specialist or ultra marathoner.⁣ So don't just track your running, learn from it with the Performance Training Journal! Check it out today on Amazon. Thank you Gut & Green! Previnex's new Gut & Green Superfoods powder is my new go-to. It has organic barley and oat grass, alfalfa, spirulina, chlorella, kale and broccoli… and that's it. Their ingredients are backed by clinical data and contain three specific gut fibers that help promote GI health, digestion, reduced inflammation, and a better microbiome. And it has twice of the fiber of my last greens mix - something I'm trying to work on. I don't always eat as many whole foods as I should, so G&G gives me more peace of Mind. Plus, the flavor actually tastes good. I don't have to choke it down so I enjoy drinking it! Try it for yourself here at previnex.com and be sure to use code "JASONGREENS" to save 15% off your first order. Don't tell anyone, but if you put Gut & Green Superfoods powder in your cart, then the 15% off discount will work for anything else you add into your cart as well. Thanks Gut & Green!

CHRISTIAN LIFE COACH COLLECTIVE- Change Your Life, Start a Coaching Business, Walk in Your Calling

FIND THE BELIEF, NOT JUST THE STORY-Clients come in describing details, emotions, and people—but the real coaching moment happens when you hear the belief underneath it all. Transformation begins when you can separate circumstance from interpretation and help the client uncover what they're making it mean. Key Takeaways The root issue is rarely the situation—it's the paradigm behind it. Ask questions that get to meaning instead of adding more detail. Awareness of interpretation brings breakthrough faster than advice. Action Guide Listen for repeated words or emotional spikes in your next session. Ask, “What are you making this mean about you?” Read the Life Coach Blog Become a Life Coach Join the Coaching FB Community —> HERE Find me @coachlauramalone on IG —> HERE Your 5 star review on Apple Podcasts means a ton✨

Let's Talk About Your Breasts
Boardrooms, Biopsies & Breakthroughs: The Unstoppable Samina Farid

Let's Talk About Your Breasts

Play Episode Listen Later Oct 30, 2025 32:27


Samina Farid built her career in oil and gas, founded her own company, and forged ahead in spaces where women are rarely seen. Through it all, she faced cancer twice and found strength that reshaped both her health and her work. Breaking barriers as the only woman in the room Building success in a male-dominated industry Facing cancer two times and turning challenges into purpose Key Questions Answered 1. How did Samina Farid cope with the challenges of being the only woman in a male-dominated field? 2. How did Samina come to start her own company, and what inspired its mission? 3. What was unique about Merrick Systems, and how did it contribute to the industry? 4. Why did Samina decide to sell her company, and what was that process like? 5.What steps did Samina take after her cancer diagnosis? 6. What did Samina learn about her genetic risk for cancer? 7. How did journaling and self-care practices help Samina during her cancer journey? 8. What message does Samina want to share with other women about health and self-care? Timestamped Overview 00:00 Discovery of Remarkable Women 04:12 Pre-Internet Oil Data Challenges 08:20 Grateful for Mentorship Journey 11:27 "Turbulent Life Changes" 15:44 Cancer Journey and Support 21:23 "Facing Cancer's Uncertainty" 24:12 Genetic Mutation: Cancer Risk Alert 25:44 Pancreatic Tumor and Whipple Surgery 28:49 Prioritize Health: Just Do It Support The Rose HERE. Subscribe to Let’s Talk About Your Breasts on Apple Podcasts, Spotify, iHeart, and wherever you get your podcasts.See omnystudio.com/listener for privacy information.

Electricpreneur Secrets - The Electrician Podcast
S3 EP04 Real Stories and Real Wins from 3 years of Electrician Breakthroughs

Electricpreneur Secrets - The Electrician Podcast

Play Episode Listen Later Oct 30, 2025 39:02 Transcription Available


This is the real kickoff. Just Joe and Clay stripped of pretense, reflecting on what it really takes to succeed in this trade, in this business… and in life. From the redemptive force of Star Wars to the raw truth about fear, belief, and bold action, this episode unpacks how electricians get stuck and how some are breaking records in their 5th month.This one is for the electrician who's felt like maybe he's not cut out for this.Who's one punch away from giving up.Who's tired of waiting to feel "ready."We're telling the truth, giving it all away, and holding nothing back.

The MAD Podcast with Matt Turck
State of AI 2025 with Nathan Benaich: Power Deals, Reasoning Breakthroughs, Real Revenue

The MAD Podcast with Matt Turck

Play Episode Listen Later Oct 30, 2025 63:15


Power is the new bottleneck, reasoning got real, and the business finally caught up. In this wide-ranging conversation, I sit down with Nathan Benaich, Founder and General Partner at Air Street Capital, to discuss the newly published 2025 State of AI report—what's actually working, what's hype, and where the next edge will come from. We start at the physical layer: energy procurement, PPAs, off-grid builds, and why water and grid constraints are turning power—not GPUs—into the decisive moat.From there, we move into capability: reasoning models acting as AI co-scientists in verifiable domains, and the “chain-of-action” shift in robotics that's taking us from polished demos to dependable deployments. Along the way, we examine the market reality—who's making real revenue, how margins actually behave once tokens and inference meet pricing, and what all of this means for builders and investors.We also zoom out to the ecosystem: NVIDIA's position vs. custom silicon, China's split stack, and the rise of sovereign AI (and the “sovereignty washing” that comes with it). The policy and security picture gets a hard look too—regulation's vibe shift, data-rights realpolitik, and what agents and MCP mean for cyber risk and adoption.Nathan closes with where he's placing bets (bio, defense, robotics, voice) and three predictions for the next 12 months. Nathan BenaichBlog - https://www.nathanbenaich.comX/Twitter - https://x.com/nathanbenaichSource: State of AI Report 2025 (9/10/2025)Air Street CapitalWebsite - https://www.airstreet.comX/Twitter - https://x.com/airstreetMatt Turck (Managing Director)Blog - https://www.mattturck.comLinkedIn - https://www.linkedin.com/in/turck/X/Twitter - https://twitter.com/mattturckFIRSTMARKWebsite - https://firstmark.comX/Twitter - https://twitter.com/FirstMarkCap(0:00) – Cold Open: “Gargantuan money, real reasoning”(0:40) – Intro: State of AI 2025 with Nathan Benaich(02:06) – Reasoning got real: from chain-of-thought to verified math wins(04:11) – AI co-scientist: hypotheses, wet-lab validation, fewer “dumb stochastic parrots” (04:44) – Chain-of-action robotics: plan → act you can audit(05:13) – Humanoids vs. warehouse reality: where robots actually stick first(06:32) – The business caught up: who's making real revenue now(08:26) – Adoption & spend: Ramp stats, retention, and the shadow-AI gap(11:00) – Margins debate: tokens, pricing, and the thin-wrapper trap(14:02) – Bubble or boom? Wall Street vs. SF vibes (and circular deals)(19:54) – Power is the bottleneck: $50B/GW capex and the new moat(21:02) – PPAs, gas turbines, and off-grid builds: the procurement game(23:54) – Water, grids, and NIMBY: sustainability gets political(25:08) – NVIDIA's moat: 90% of papers, Broadcom/AMD, and custom silicon(28:47) – China split-stack: Huawei, Cambricon, and export zigzags(30:30) – Sovereign AI or “sovereignty washing”? Open source as leverage(40:40) – Regulation & safety: from Bletchley to “AI Action”—the vibe shift(44:06) – Safety budgets vs. lab spend; models that game evals(44:46) – Data rights realpolitik: $1.5B signals the new training cost(47:04) – Cyber risk in the agent era: MCP, malware LMs, state actors(50:19) – Agents that convert: search → commerce and the demo flywheel(54:18) – VC lens: where Nathan is investing (bio, defense, robotics, voice)(68:29) – Predictions: power politics, AI neutrality, end-to-end discoveries(1:02:13) – Wrap: what to watch next & where to find the report (stateof.ai)

UncleRob, Everybody's Mentor
Ep 183: "Could Life Sciences Power the Next California Boom?" with Dave Whelan

UncleRob, Everybody's Mentor

Play Episode Listen Later Oct 30, 2025 90:56


Is our Life Sciences industry the most under-reported unicorn in California's industrial dominance? Can Life Sciences innovation survive the USA government's assault on science? In this eye-opening episode, Rob sits down with friend Dave Whelan, to uncover how LA is rapidly transforming into a major player in biotech and health innovation. They discuss groundbreaking projects like UCLA's new Research Park, the explosion of AI in drug discovery, and how diversity and storytelling are shaping the future of healthcare and life sciences startups. From political roadblocks to billion-dollar opportunities, this conversation is packed with insights for anyone curious about where health tech is heading—and why LA might just be leading the charge.Feel free to follow and engage with DAVE here:LinkedIn: https://www.linkedin.com/in/djwhelan/Instagram: https://www.instagram.com/djwhelanX: https://x.com/djwhelanFacebook: https://www.facebook.com/djwhelanWebsite: https://www.bespokestrategy.com/whelanWe're so grateful to you, our growing audience of entrepreneurs, investors and community leaders interested in the human stories of the Entrepreneurial Thinkers behind entrepreneurial economies worldwide.As always we hope you enjoy each episode and Like, Follow, Subscribe or share with your friends. You can find our shows here, and our new Video Podcast, at “Entrepreneurial Thinkers” channel on YouTube. Plug in, relax and enjoy inspiring, educational and empowering conversations between Rob and our guests.¡Cheers y gracias!,Entrepreneurial Thinkers Team.Chapters00:00 Introduction to Entrepreneurial Thinkers04:46 The Evolution of Life Sciences in California19:03 UCLA Research Park: A New Era for Innovation28:37 The Vision for Life Sciences Development33:31 The Role of Universities in Life Sciences37:23 Navigating Funding Challenges in Academia47:03 Breakthroughs in Life Sciences and AI's Impact56:55 Understanding Neurodegenerative Diseases58:47 Diversity in Innovation and Health Sciences01:06:37 The Importance of Storytelling in Health Tech01:11:56 Dave Whelan's Multifaceted Career and Contributions01:18:04 Key Mistakes in Health Tech Innovation

Pharma and BioTech Daily
Navigating Pharma's New Frontiers: Breakthroughs and Challenges

Pharma and BioTech Daily

Play Episode Listen Later Oct 30, 2025 6:20


Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're exploring a series of significant developments that underscore the rapid evolution within these industries.Starting with one of the major players, Merck, which has been strategically adjusting its focus in light of Keytruda's looming loss of exclusivity. The company has demonstrated remarkable progress with Welireg in kidney cancer trials, successfully pairing it with Keytruda. This combination therapy is a beacon of hope for Merck as it faces the challenges of patent expiration, highlighting the growing trend toward leveraging combination treatments to enhance efficacy in cancer therapies. This approach not only pushes the boundaries of cancer treatment but also paves the way for future therapeutic innovations. In contrast, Merck and Eisai have decided to cease their pursuit of a Keytruda-Lenvima pairing for a specific liver cancer subtype after failing to achieve overall survival benefits, despite earlier progress-free survival gains. Such developments highlight the inherent uncertainties in oncology drug development, where initial promising results may not always lead to long-term survival advantages.Meanwhile, Eli Lilly is making headlines with its substantial $1.2 billion investment to upgrade its Puerto Rico manufacturing facility. This move is aligned with their strategy to amplify production capabilities for oral drugs, particularly focusing on their promising GLP-1 pill, Orforglipron. The investment signifies a robust commitment to addressing diabetes and potentially other metabolic disorders through an expanded and more efficient production pipeline. Additionally, Eli Lilly's collaboration with NVIDIA aims at constructing an unprecedented supercomputer tailored for pharmaceutical research. This initiative leverages advanced computational power to accelerate drug discovery processes and enhance data analysis capabilities—a testament to how AI and machine learning are streamlining research workflows for developing more effective therapeutics.On the regulatory stage, Akebia Therapeutics has opted to cancel a trial for its anemia drug Vafseo after discussions with the FDA. This decision sheds light on the intricate challenges companies encounter while navigating regulatory landscapes and optimizing clinical trial strategies to ensure market success.In legal news, Kenvue is preparing for a lawsuit filed by Texas Attorney General Ken Paxton regarding alleged deceptive marketing practices about Tylenol's safety during pregnancy and its purported link to autism risk. This case emphasizes the necessity for pharmaceutical companies to uphold rigorous scientific evidence supporting their marketing claims while navigating potential legal challenges.Strategically, WuXi AppTec's decision to divest its China-based clinical research units marks a broader industry trend of streamlining operations to concentrate on core competencies. By focusing resources on its Contract Research Development and Manufacturing Organization (CRDMO) platform, WuXi aims to leverage growth opportunities in this burgeoning sector.In a notable technological partnership, Johnson & Johnson's medical technology division and Verily have entered agreements with NVIDIA, highlighting the increasing intersection of artificial intelligence with life sciences. These collaborations are poised to advance AI applications within healthcare, potentially transforming areas such as data analysis, diagnostics, and personalized medicine.The industry is also feeling the impact of governmental actions, as evidenced by a federal government shutdown starting October 1st that has led to indefinite blocks on federal worker firings. Such political developments can significantly affect healthcare funding and policymaking processes.These stories collectively paint a piSupport the show

Space Cats Peace Turtles
428: Breakthroughs and Synergies RANKED

Space Cats Peace Turtles

Play Episode Listen Later Oct 29, 2025 210:01


Yo this week, Hunter and JadiimJedi sit down to rank and discuss all 25 breakthroughs for the old factions. It's a blow-out discussion that essentially covers the entire game in brief excluding the newest factions. Also for the first 45 minutes we review the new rules for breakthroughs and synergies in an attempt to clear up some confusion. HAVE FUN! Thunder's Edge, forver. For Twilight Imperium Tournaments and SCPT live-shows, click here: https://linktr.ee/spacecatspeaceturtles   Music provided by Ben Prunty. Find more at benpruntymusic.com or benprunty.bandcamp.com Additional Music and Sounds by Brian Kupillas. https://wanderinglake.bandcamp.com/ Art by Sun To learn more about our Discord, Patreon, Merch, and more, visit https://spacecatspeaceturtles.com/

MedEvidence! Truth Behind the Data
From Probing Prostates to Bladder Breakthroughs

MedEvidence! Truth Behind the Data

Play Episode Listen Later Oct 29, 2025 30:22 Transcription Available


Send us a textUrologist Dr. Yaw Nyame joins Dr. Michael Koren to discuss bladder and prostate cancers. Dr. Nyame talks about his journey through college - including the choice between rock stardom and medical school - and how he got to the Fred Hutch Cancer Center in Seattle. Dr. Nyame explains symptoms, the history, and treatments for prostate and bladder cancer. He tells us "if you have blood in the urine, you definitely want to get to your primary care doctor." He also expands on gaps in cancer outcomes for Black men. Along the way, we weigh benefits and harms of PSA screening and talk honestly about sexual health after treatment.Show Note: Lynch syndrome is a genetic condition also known as hereditary nonpolyposis colorectal cancer (HNPCC). It represents an increased risk of several cancers, including colorectal, endometrial, gastric, ovarian, and pancreatic cancer. It is caused by an error in the DNA mismatch repair mechanism, which normally corrects for random insertions into the DNA code.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

The Health Ranger Report
Brighteon Broadcast News, Oct 28, 2025 - New AI breakthroughs NULLIFY CENSORSHIP and bypass pharma-controlled false narratives

The Health Ranger Report

Play Episode Listen Later Oct 28, 2025 101:45


- Improvements in Sensor Dot News and AI Engine (0:10) - Demonstration of AI-Generated News Content (3:16) - Development and Impact of Brighteon.ai (6:55) - Introduction of Grokipedia and Naturalpedia (9:46) - Challenges and Future Plans for AI Projects (14:03) - Launch of Vaccine Forensics Website (24:24) - Features and Capabilities of Vaccine Forensics (31:36) - Importance of Independent Media and AI Engines (44:25) - Special Reports on UBI and Food Riots (57:35) - Food Stamp Program and Its Impact on Society (1:20:38) - Political Benefits and Potential Violence (1:25:05) - Economic and Social Consequences (1:33:51) - Preparation and Safety Measures (1:38:28) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com

Biohacking Superhuman Performance
#382: Building Stronger Women from their 20s to their 70s: Hormones, Iron Testing, and Menopause Breakthroughs With Dr. Amy Killen

Biohacking Superhuman Performance

Play Episode Listen Later Oct 28, 2025 53:57


Today, I'm thrilled to welcome Dr. Amy Killen, a visionary in hormone optimization and regenerative medicine who is transforming the conversation around women's health and longevity. In this episode, Dr. Killen shares her personal journey—from witnessing her mother's struggle after a hip fracture, to becoming a steadfast advocate for correcting the myths and misinformation that still surround estrogen, progesterone, and testosterone optimization. Episode Timestamps: Ferritin, iron, and hormonal health basics ... 00:00:43 Dr. Amy Killen's evolving hormone focus ... 00:04:02 Women's Health Initiative and estrogen myths ... 00:06:31 Importance of hormone optimization vs. stem cells ... 00:10:25 Testosterone for women: symptoms, labs, delivery options ... 00:12:05 Side effects and nuances of testosterone therapy ... 00:14:01 SHBG, free testosterone, and lab variability ... 00:16:38 Libido, PT-141, and the biopsychosocial lens ... 00:21:46 Iron and ferritin: sweet spot and skin implications ... 00:29:16 Hot vs. HRT: definitions and individualization ... 00:34:23 Debunking estrogen and breast cancer myths ... 00:41:30 Aging expectations and finding the right doctor ... 00:43:18 Advice for women by decade—20s, 30s, 40s, etc. ... 00:47:20 Our Amazing Sponsors: Tro Zzz by Troscriptions - This isn't just melatonin—it's a powerhouse! Oblipair gives you honokiol and agarin to enhance GABA binding, while adenosine and cordycepin boost sleep drive and deep sleep. CBD, CBN, and 5‑HTP round it out. Head to troscriptions.com, use NAT10, and get 10% off your first order. NMN+G Rx by Wizard Sciences - A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase. Probiotic Breakthrough by Bioptimizers: uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

cityCURRENT Radio Show
Lauren Ready highlights book, Ask Like a Leader, how questions turn blindspots into breakthroughs

cityCURRENT Radio Show

Play Episode Listen Later Oct 28, 2025 16:14


Host Jeremy C. Park talks with Lauren Ready, Owner and Principal Storyteller with Forever Ready Productions and author of the new book, "Ask Like a Leader: A Method for Revealing Deeper Truth and Turning Blindspots into Breakthroughs," who highlights how her background in journalism and broadcast news taught her the importance of asking the right questions and how her current work in mission-driven storytelling led her to write the book and share The Question Lens that she developed and refined over the years. During the interview, Lauren shares her career journey from a high school job shadow to becoming a journalist and eventually founding Forever Ready Productions, a mission-driven storytelling company that has helped nonprofits raise over $18 million through film and video-driven fundraising projects and content creation. She discusses her development of "The Question Lens" framework and breaks down the process, which is shared in "Ask Like a Leader" to help leaders improve communication and connection through better questioning techniques. The book, which draws parallels between leadership challenges and documentary filmmaking, is available in multiple formats, and Lauren continues to work with nonprofits and small businesses through her production company while offering keynotes focused on sharing takeaways from her book.Journalist's Journey to Mission-Driven Storytelling - Lauren Ready discusses her journey from a high school job shadow to becoming a journalist and eventually transitioning to storytelling through Forever Ready Productions. She explained how her experiences in news reporting led her to focus on impactful, mission-driven storytelling for nonprofits and organizations, and she talks about founding Forever Ready Productions in 2014 as a side hustle. She describes how her husband's business plan for the company led her to take the leap of faith and then transition from a solo operation to hiring staff, eventually helping nonprofits raise over $18 million through film and video-driven fundraising projects and content creation. The company has won Emmys for documentary work and helped change Tennessee law, with Lauren emphasizing their mission to inspire action and transform perspectives through storytelling.Leadership Through Question-Based Framework - Lauren explains how she developed the concept for her book, "Ask Like a Leader," while hiking in the mountains, realizing that her career in storytelling, journalism, and documentary work was rooted in the ability to ask better questions. She has created a question-based framework called "The Question Lens" to help leaders improve communication, connection, and innovation. The book aims to provide a method for revealing deeper truths and turning blind spots into breakthroughs, drawing parallels between leadership challenges and the process of documentary filmmaking.OSCARS of Effective Communication Framework - Lauren and Jeremy discuss the framework of the "OSCARS" for effective communication, which includes open-ended questions, specific follow-up questions, clarifying questions, active listening, reflection questions, and sharing. Lauren emphasizes that leaders should focus on the quality of their questions rather than seeking to know everything, highlighting the importance of being present, curious, and open to learning. They agree that better questioning leads to deeper connections, understanding, and empathy, which are crucial for leadership and personal growth.Overcoming Expertise Blind Spots - Lauren discusses the concept of the Paradox of Expertise, where leaders who are experts in their field may develop blind spots due to their extensive knowledge and experience. She emphasizes the importance of shifting from certainty to curiosity and from knowing to noticing, encouraging leaders to ask questions even when they think they have the answers. Lauren shares a personal example from her experience as a founder, where she accidentally derailed a team member's creativity by providing immediate feedback instead of asking questions. She stresses the need for self-awareness and reflection in leadership roles to recognize one's own role in team issues and to help team members grow.Lauren's Book and Future Projects - Lauren discusses where individuals can purchase "Ask Like a Leader," which is available on Amazon and her website LaurenReady.com/books, where readers can purchase both paperback and ebook versions. She announced that the audiobook version will be available for free with paperback purchases and separately on Audible in December or January. Lauren encourages listeners to leave reviews and mentions that she is considering writing a follow-up book, particularly to help nonprofit professionals and fundraisers. She also shares information about ForeverReadyLLC.com, where viewers can learn more about her documentary work and services for nonprofits and small businesses.Visit https://www.laurenready.com/books to learn more.

Pharma and BioTech Daily
Biotech Breakthroughs: Transformative Acquisitions and FDA Milestones

Pharma and BioTech Daily

Play Episode Listen Later Oct 28, 2025 5:25


Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into several significant shifts in the industry, marked by scientific advancements, regulatory changes, and strategic corporate maneuvers.Starting with a major acquisition, Novartis has strategically purchased Avidity Biosciences, a San Diego-based biotech company specializing in muscular dystrophy treatments, for a striking $12 billion. This substantial investment underscores Novartis's dedication to expanding its neuroscience portfolio. Avidity's innovative RNA-based therapies show great promise for treating neuromuscular diseases, highlighting a broader industry trend where large pharmaceutical companies are investing heavily in late-stage biotech firms to bolster their pipelines with cutting-edge technologies. Such moves are pivotal as they align with the growing emphasis on precision medicine and the development of novel therapeutic options for conditions with limited existing treatments.In other acquisition news, Eli Lilly has expanded its gene therapy portfolio through acquiring Adverum Biotechnologies for up to $262 million. This acquisition is expected to bolster Eli Lilly's position in the gene therapy space, particularly in ophthalmology. Gene therapy offers transformative potential by directly addressing underlying genetic causes of diseases, with Adverum's focus on ophthalmic conditions potentially offering innovative solutions for unmet medical needs in eye-related disorders. The acquisitions by Novartis and Eli Lilly reflect broader trends within the pharmaceutical industry where companies actively seek to diversify their pipelines through mergers and acquisitions. These transactions emphasize strategic incorporation of advanced biotechnologies such as RNA therapeutics and gene therapy into development portfolios aiming to deliver breakthroughs in patient care.On the regulatory front, Bayer has achieved a milestone with the U.S. FDA approval of Lynkuet (elinzanetant), a nonhormonal medication designed to manage menopause symptoms. This approval represents a significant step forward in providing alternative treatment options to a traditionally hormone-reliant segment, emphasizing the industry's shift towards diversifying therapeutic solutions and addressing unmet medical needs. This move highlights continuous efforts to address women's health issues through new pharmacological interventions.Meanwhile, Merck's Winrevair has received an updated FDA label following successful results from the Phase 3 Zenith trial. This label expansion is anticipated to enhance its market position, potentially propelling Winrevair to blockbuster status. These developments highlight the critical role of rigorous clinical trials in validating drug efficacy and safety, which ultimately influence regulatory decisions and market dynamics.BridgeBio has also made headlines with its successful Phase 3 trial for a rare disease candidate. By demonstrating significant improvements in clinical outcomes and biomarkers, BridgeBio is poised to file for FDA approval. This reflects an increasing focus on precision medicine within the industry, particularly in addressing rare and genetic disorders.In diabetes management news, Innovent and Eli Lilly's mazdutide has outperformed Novo Nordisk's semaglutide in a head-to-head study focused on glucose regulation and weight loss. As a GLP-1/glucagon dual receptor agonist, mazdutide offers broader therapeutic effects, showcasing the competitive landscape in metabolic disorders where novel mechanisms are vying for superiority.Regulatory activities remain pivotal, as demonstrated by Syndax receiving a second indication for its leukemia drug Revuforj. Such expansions underscore the importance of ongoing clinical research and regulatory engagement in maximizing a drug's therapeutic reach.NSupport the show

Coaches Council
Go S.L.O.W. to Go Fast: Stillness, Listening, Obedience & Wisdom — A Framework for Breakthroughs

Coaches Council

Play Episode Listen Later Oct 27, 2025 17:32


Send us a textEpisode OverviewIn this episode of The Own It Show, host Justin Roethlingshoefer reframes “slowing down” as the doorway to breakthrough. If you've been chasing certainty, quick fixes, or the next hack, Justin shows why true progress lives on the other side of obedience—and how to reach it through his S.L.O.W. framework: Stillness → Listen → Obedience → Wisdom.Blending behavioral science, stress physiology, and Scripture, he explains why our brains resist obedience (control, instant gratification, loss aversion, and misunderstanding God's heart), and how practicing stillness and listening raises HRV, calms cortisol, sharpens decision-making, and creates spiritual alignment. He also shares a personal story—choosing integrity over a “bigger” opportunity—that opened unexpected doors and confirmed a simple truth: obedience precedes blessing.Episode Highlights- Why We Resist Obedience: Control vs. trust, impatience & dopamine, loss aversion, and a distorted view of God's heart.S.L.O.W. Framework:S — Stillness: Downregulates stress, raises HRV (readiness), and opens receptivity. (Ps. 46:10)L — Listen: Quiet the noise to hear the whisper, not the shout. (1 Kings 19:12)O — Obedience: The hinge between hearing and harvest. (Luke 5:5)W — Wisdom: Fruit of consistent, values-aligned obedience; rewires the brain for clarity and resilience (neuroplasticity).- Science of Slowing Down: Calm-state decisions are more accurate and less reactive; trust signals lower cortisol and increase oxytocin/serotonin.- Story of Integrity: Saying “yes” to a smaller platform led to a greater calling—proof that character-driven obedience compounds.- Faith Lens: “Anyone who loves me will obey my teaching.” (John 14:23) Blessing follows alignment, even when the path feels costly.Action Steps- Daily 5-Minute Stillness: Begin each morning with uninterrupted quiet—no phone, no notes—just breathing and presence.- Practice Active Listening: Journal any “nudges” you sense; ask, “What's the next right obedient step?”- One Act of Obedience Today: Choose a small, specific yes (or no) aligned with your values. Log it and the outcome.- Evening Reflection: Trace fruit back to prior acts of obedience; look for the 3–24 month “compounding” effect.- Reduce Reactivity: Use a simple wind-down (3-2-1: 3 hrs no heavy food, 2 hrs no work, 1 hr no screens) to keep cortisol low and decisions clear.Scripture & Studies Mentioned- Psalm 46:10 — “Be still and know…”- 1 Kings 19:12 — God's whisper, not the whirlwind- Luke 5:5 — Obedience → Overflow- Proverbs 3:5–6 — Trust → Straight paths- John 14:23 — Love → Obedience → Presence- Behavioral notes on loss aversion, dopamine & instant rewards, and calm-state decision quality (e.g., HBR insights; Stanford findings referenced in discussion)===========================Subscribe and Listen to the Own It Show HERE:➡︎ YouTube:https://www.youtube.com/@justinroethlingshoefer➡︎ Apple Podcasts:https://apple.co/3KCyN3j➡︎ Spotify: https://open.spotify.com/show/3F58Ez4lbIKQ6kMu2pfpIG===========================Resources:⚡️CHECK OUR PROGRAMS: https://ownitcoaching.com/programs/⚡️BOOK: https://thepowerofownershipbook.com/=========================== Connect with Justin Roethlingshoefer on Social Media:➡︎ linkedin.com/in/justin-roethlingshoefer➡︎https://www.instagram.com/justinroeth/?hl=en

The Hydrogen Podcast
Hydrogen's Real Progress – Daimler's Supply Push, Catalyst Breakthroughs & Plant Safety Lessons

The Hydrogen Podcast

Play Episode Listen Later Oct 27, 2025 7:50 Transcription Available


In this episode of The Hydrogen Podcast, we unpack three pivotal stories shaping hydrogen's next chapter—from major logistics partnerships and cost-slashing tech breakthroughs to a data-driven look at plant safety and reliability.

The Janice Dean Podcast
Strength Through Struggle: Tim Green's Next Chapter

The Janice Dean Podcast

Play Episode Listen Later Oct 26, 2025 20:04


Breakthroughs in technology are transforming life with ALS, empowering people to communicate, create, and inspire in ways once thought impossible. Janice is joined by former NFL star and best-selling author Tim Green, who has defied all odds since his 2016 ALS diagnosis. Using eye-tracking and AI technology, Tim continues to write, raise millions for ALS research, and share a powerful message of faith, perseverance, and hope through his new book, Rocket Arm. Rocket Arm Tim Green Nothing Left Unsaid Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Dating Den
From Fear to Fulfillment: Unlocking Your Ikigai and Creating a Life You Love

The Dating Den

Play Episode Listen Later Oct 25, 2025 38:59


Mary Olson-Menzel is a nationally recognized expert in career and workplace success with over 30 years of leadership experience across media, tech, healthcare, and even the NFL. As the founder and CEO of MVP Executive Development, she's coached everyone from Fortune 500 leaders to parents reentering the workforce—helping them find purpose, confidence, and a plan to do what truly lights them up. In this inspiring episode, we unpack the mindset and tools to thrive through massive change, find your “reason for being,” and design work—and a life—that truly lights you up.    

Your Retirement Navigator
Beyond the Paycheck: Retirement Roadblocks & Breakthroughs

Your Retirement Navigator

Play Episode Listen Later Oct 25, 2025 30:01


Ready to swap your morning commute for a leisurely coffee, but wondering how to keep those paychecks flowing after retirement? This week on "Your Retirement Highway," Matthew Allgeyer takes the wheel solo and invites you to rethink how retirement really works. From budget blind spots to the pitfalls of the “4% rule” and the warning signs your advisor might be taking the wrong route, Matt pulls back the curtain on what can make or break your retirement journey. Ever considered sneaking your own investment account past your advisor, or wondered if your nest egg will survive a stormy market? You're not alone—and it's time to get answers.But hold on, there's more than market moves and numbers on a spreadsheet. What happens when life throws a curveball—like a recession, family surprises, or those curveballs no one sees coming? Find out why contingency planning is the ultimate secret to stress-free golden years, and how a second opinion just might be the ticket to your best retirement yet. Listen now and learn how to cruise smoothly past the roadblocks—and maybe, just maybe, land on cloud nine with your retirement plans.

150K podcast
Turning Loss into Launches: Lorna Scott on Creative Breakthroughs and Bold Business Moves

150K podcast

Play Episode Listen Later Oct 23, 2025 49:59


In this transformative episode, Joseph Graham sits down with Lorna Scott—known widely as the “Creative Solution Finder”Lorna Scott helps women entrepreneurs over 50 reclaim clarity, purpose, and control in their businesses so they can stop feeling overwhelmed and start running their businesses with confidence, ease, and alignment. But her journey to becoming a sought-after “Creative Solution Finder” wasn't a straight path.Like many of the entrepreneurs she works with, Lorna knows what it's like to feel stuck in the endless cycle of doing more, yet never feeling like it's enough. She's faced the pull of competing priorities, the weight of uncertainty, and the struggle to stay connected to the passion that once fueled her. It wasn't more effort that changed everything. It was clarity.Her transformation began with deep personal development work, extensive training in coaching and marketing, and a hard-earned understanding and experience that success isn't about doing more. It's about doing what matters. Through years of experience she developed a process to help others break free from overwhelm, align their business with their core values and finally build something that works for them.Lorna's work is shaped by her time learning from Jack Canfield, co-author of The Success Principles. As a graduate of Jack's Train the Trainer program and a member of his assisting teams for over six years, she gained firsthand experience in guiding individuals to achieve life-changing results. As a Certified Passion Test Facilitator, she also helps clients uncover what truly drives them so their business supports their life, not the other way around.Beyond her work, Lorna is happiest surrounded by her family, including her six grandsons who keep her on her toes. You might also find her playing the flute with the Medicine Hat Community Concert Band, a passion that reminds her of the importance of harmony - in both music and in life.Lorna believes anything is possible when you strip away the distractions, focus on what truly matters, and have the courage to create a business that aligns with your purpose. Her mission is to help women entrepreneurs stop going through the motions and start leading so they build a business that works for them. Without sacrificing what matters most to them. Whether you're navigating loss, reimagining your brand, or seeking clarity in your next launch, this episode offers a roadmap to rise, rebuild, and lead with purpose.​How to turn emotional upheaval into entrepreneurial fuel​The hidden link between lead generation and low course sales​Why most marketing courses miss the mark—and what to do instead​Building rock-solid relationships with your dream clients​The mindset shift that unlocks bold breakthroughs​Lorna's journey from grief to growth—and how it shaped her mission​Insights from top marketing mentors and how she applies them​The power of flute-playing, family, and finding joy in the everyday​Certified Trainer in the Canfield Methodology​Certified Passion Test Facilitator​Executive Coach with Opposite Strengths​Launch strategist and Facebook ad campaign expert​Community musician and proud grandmother from Medicine Hat, Alberta“With the right information, attitude, focus, and belief in yourself, you can achieve your highest goals—no matter what phase of life you're in.”

Skinny Dipping
think less, receive more: the science of breakthroughs

Skinny Dipping

Play Episode Listen Later Oct 21, 2025 27:27


full VIDEO experience here on youtube

Brilliant Balance
Think inside the box: How constraints can lead to creative breakthroughs with Sheri Jacobs

Brilliant Balance

Play Episode Listen Later Oct 21, 2025 24:39


In this episode, I'm joined by Sheri Jacobs, an accomplished entrepreneur, bestselling author, keynote speaker, and passionate advocate for creative breakthroughs. She's here to help us rethink everything we know about boundaries! We often hear that endless options drive innovation, but Sheri shows us how setting the right boundaries can actually ignite creativity and teamwork. She brings impactful stories and inspiration, from her arctic wildlife photography adventures to behind-the-scenes moments with leading companies like Bank of America, demonstrating how a few smart limits can lead to sharper solutions. She shares practical ways to create more clarity and space for what matters, at work and at home, even while juggling busy family lives and bold aspirations. If you feel overwhelmed by all you “should” be doing or struggle to find space for your passions, this episode offers fresh tools to help you choose what truly matters and design your most vibrant season yet. Listen in to learn how setting sensible limits can spark your next great idea. Show Highlights: Sheri Jacobs' wisdom on boundaries with a Miles Davis insight. [02:08] The myth that boundaries restrict rather than provide clarity. [03:50] How fewer options within constraints led to a winning arctic wildlife photo. [05:01] Tatiana Goodman's findings on how fences foster creative play. [09:28] Why Bank of America's “Keep the Change” program is successful. [12:33] Advice for women to break through ceilings by narrowing focus. [15:14] Beat FOMO and overwhelm with a priority correction. [16:53] How to get more done by setting a firm bedtime. [19:36] The power of a capsule wardrobe and curbing fashion excess. [21:36] Where are you not setting yourself free by creating a boundary? [22:46] To find Sheri's work and her books, go to https://www.sherijacobs.com/. Subscribe to the Brilliant Balance Weekly: www.brilliant-balance.com/weekly Follow Cherylanne on Instagram: www.instagram.com/cskolnicki Join the Brilliant Balance Facebook Group: www.facebook.com/groups/281949848958057

Think Fast, Talk Smart: Communication Techniques.
237. Mistake It Till You Make It: Learn Faster and Fail Smarter

Think Fast, Talk Smart: Communication Techniques.

Play Episode Listen Later Oct 21, 2025 27:03 Transcription Available


Why we learn the most when we accept that we might be wrong.Effective communication isn't about having all the answers. As Astro Teller knows, it's about finding (and sometimes fumbling) your way through the questions.Teller is a computer scientist, entrepreneur, and inventor who serves as Captain of Moonshots at X, Alphabet's Moonshot Factory. In his work leading teams toward audacious solutions to seemingly unsolvable problems, he embraces what he calls “a learning journey,” where being wrong isn't the end, but the beginning. “As scary as it is to be wrong,” he says, it's a necessary part of the discovery process. Whether experimenting in the lab or testing our thoughts and opinions in conversation with others, it's about having the humility and curiosity to face the limits of our understanding. “When do you learn something? You learn something when you have a model about the world, and then you get some data that tells you you're wrong,” he says. “You learn nothing when you're right.”In this episode of Think Fast, Talk Smart, Teller and host Matt Abrahams discuss how embracing uncertainty drives innovation, why leaders should reward learning habits over outcomes, and how we learn the most when we're not afraid to find that we might be wrong.To listen to the extended Deep Thinks version of this episode, please visit FasterSmarter.io/premium.Episode Reference Links:Astro TellerAstro's Book: Sacred Cows Ep.70 Ideas Fuel Innovation: Why Your First Ideas Aren't Always the Best Ep.20 Question Your Questions: How to Spark Creativity in Your Communication Connect:Premium Signup >>>> Think Fast Talk Smart PremiumEmail Questions & Feedback >>> hello@fastersmarter.ioEpisode Transcripts >>> Think Fast Talk Smart WebsiteNewsletter Signup + English Language Learning >>> FasterSmarter.ioThink Fast Talk Smart >>> LinkedIn, Instagram, YouTubeMatt Abrahams >>> LinkedInChapters:(00:00) - Introduction (02:18) - Defining a Moonshot (04:21) - Building a Learning Machine (07:00) - Learning vs. Productivity (08:35) - Capturing and Sharing Learning (10:49) - Rewarding Habits, Not Outcomes (13:17) - Moonshot Success Stories (16:16) - The Power of Storytelling in Innovation (17:46) - Launching The Moonshot Podcast (19:37) - The Final Three Questions (25:27) - Conclusion  ********Thank you to our sponsors.  These partnerships support the ongoing production of the podcast, allowing us to bring it to you at no cost.This episode is brought to you by Babbel. Think Fast Talk Smart listeners can get started on your language learning journey today- visit Babbel.com/Thinkfast and get up to 55% off your Babbel subscription.Support Think Fast Talk Smart by joining TFTS Premium.