Podcasts about tell everyone

Do discs matter anymore? This week, host Jorden Guth is joined by Rob Jones, president of Magnetar Audio North America, to discuss the brand's high-performance universal disc players, the fuzzy lines between hi-fi and home theater, and the future of physical media. Source: “Magnetar UDP900 4K Ultra HD Universal Blu-ray Disc Player–DAC” by Roger Kanno: https://www.soundstagehifi.com/index.php/equipment-reviews/1854-magnetar-udp900-4k-ultra-hd-universal-blu-ray-disc-player-dac Chapters: 00:00:00 Announcement 00:00:30 The road to Magnetar 00:23:23 Music Break: “IDK” by Modern Aquatic 00:24:15 The intersection of home theater and hi-fi 00:37:47 Outro: “Let's Not Rush Out and Tell Everyone” by Glories

"Dream Big" is our series to kick off 2025 at Fusion Christian Church where we look to set godly goals. In this message, Pastor Zac explains the vision of our church and the simple truth behind our mission statement: Love God, Love Others, Tell Everyone.To fulfill a big vision, we must build on a godly foundation.If God is not the cornerstone of the church, we may as well quit building. If God does not direct the building, the building will fail. We must continually work to ground our church in God and his word. With that said, what is the purpose of our church? Why do we exist as a church?We exist to Love God.The first and greatest commandment is to love God, and we can show our love for God in three major ways. First, by loving Christ the Son. Christ is the image of the invisible God, and if we do not love Christ, we do not love God. Second, we love God by loving and obeying his word. If we love God, we should love to read what he has written for us. To take it a step further: we should love to live out the commands he has given us as well. Third, we show our love for God by loving prayer. It does not make sense to say we love someone if we never speak to them. Prayer is our way to communicate with God, and if we love God then we should love prayer.We exist to Love Others.This is the second greatest commandment: to love your neighbor as yourself. At Fusion Christian Church, we believe that the duty of all Christians is to love other people. How can we love others? One of the best ways is by serving them. If we are willing to serve others and work for their good, we demonstrate our love for them. On a personal level, we can also show our love for others by expressing care and interest in them. Simply getting to know people is essential for knowing how to love them better. We exist to Tell Everyone the good news about Jesus.The most important way to love someone is to tell them the gospel. In fact, the most loving thing anyone can do for another is to tell them about Jesus Christ. Salvation is found in no other name than the name Jesus, and we, Christians, must share that name wherever we go. How can you share the gospel with those around you this year?

Relationship Reddit Stories, OP wants to reach out and tell people what's going on in their lives to get some support but in doing so will betray her husband.

While Nate is off in South Carolina, Reese welcomes Liam Reilly, fellow Communications/Sports Journalism student! Following an unfortunate Patriots loss at the Jets, Reese and Liam analyze the game and then transition into the "Create the Perfect Life" game. Here is the rundown: (0:45) Introduction: Welcome Liam Reilly (4:49) Recap: New England Patriots vs. New York Jets (5:28) Drake Maye Drive Stat to Tell Everyone (12:17) “Now here's a guy.” -Reese (16:49) Tyler Conklin History (18:55) Kickoff Rule Question (29:11) Hot Takes: Nate Emerton on the Phone (32:54) “You took notes from Cheetos.” -Reese (34:20) “I mean, that logically, I get it. But not hot takey.” -Nate (34:38) Game Time: Create the Perfect Life (44:53) Preview: New England Patriots vs. San Francisco 49ers (46:52) The Just a Little Bit Moment

Daily Dad Jokes (27 Sep 2024)The official Daily Dad Jokes Podcast electronic button now available on Amazon. The perfect gift for dad! Click here here to view!Email Newsletter: Looking for more dad joke humour to share? Then subscribe to our new weekly email newsletter. It's our weekly round-up of the best dad jokes, memes, and humor for you to enjoy. Spread the laughs, and groans, and sign up today! Click here to subscribe!Listen to the Daily Dad Jokes podcast here: https://dailydadjokespodcast.com/ or search "Daily Dad Jokes" in your podcast app.Interested in Business and Finance news? Then listen to our sister show: The Daily Business and Finance Show. Check out the website here or search "Daily Business and Finance Show" in your podcast app.Jokes sourced and curated from reddit.com/r/dadjokes.Joke credits: Left-Distribution-13, Garrod_Ran, Namnrocinu, Strict_Berry7446, m1dlife-1derer, gotmojo6, Potential-Fudge-8786, Ok_Presence36, Sir_Pluses, CheeseyGarlicBread10, Masselein, Ok_Presence36, , Man-e-questions, StockInitial4460, Ok_Presence36, shadowariser, CheeseyGarlicBread10, Joel_Boyens, nucleardkSubscribe to this podcast via:iHeartMediaSpotifyiTunesGoogle PodcastsYouTube ChannelSocial media:InstagramFacebookTwitterTikTokDiscordInterested in advertising or sponsoring our show? Contact us at mediasales@klassicstudios.comProduced by Klassic Studios using AutoGen Podcast technology (http://klassicstudios.com/autogen-podcasts/)See omnystudio.com/listener for privacy information.

Does self-promotion make you uncomfortable? You need to start — because if you don't talk yourself up, nobody else will! On today's episode, I offer my four rules of self-promotion, four ways to talk yourself up if you're afraid to do it, and then how to handle the inevidable haters. These are all tips from my newsletter, One Thing Better.

Does self-promotion make you uncomfortable? You need to start — because if you don't talk yourself up, nobody else will! On today's episode, I offer my four rules of self-promotion, four ways to talk yourself up if you're afraid to do it, and then how to handle the inevidable haters. These are all tips from my newsletter, .

Fr Toby on the grace given to St Dominic for the world. WORD FOR TODAY is broadcast live on Radio Maria on weekdays at 1:15pm and is rebroadcast at 12:15am and 5:45am the following day. In it our Priest Director Fr Toby offers a reflection, usually drawing from the Mass readings of the day.  If you enjoyed this programme, please consider making a once off or monthly donation to Radio Maria England by visiting www.RadioMariaEngland.uk or calling 0300 302 1251 during office hours. It is only through the ongoing support of our listeners that we continue to be a Christian voice by your side.

Show Features: Internet Is Undefeated, Blooper Reel and Redneck Report Socials: @DaveandMahoney   Voice Mail: 833-Yo-Dummy   https://www.twitch.tv/daveandmahoney   Additional Content: daveandmahoney.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Message by Pastor Blake   

Hour 4 - During the fourth hour of the Greg Hill Show the crew begins by having a long chat with Donnie Wahlberg of Blue Bloods and of the front row at every Celtics game.  Then, an angry Red Sox caller vents his frustration about batting a rookie in the ninth inning.  Finally, the crew reacts to the Justin Jefferson contract extension.

Matthew 28:16-20 This is the last in our Easter series. If you remember last week, Jesus rose from the grave, defeating death and making a way for us to come to the Father through His sacrifice on the cross. But…what happened after? Join us as we learn about the great commission. Kids will understand the definition of commission and what Jesus told them to do. They will understand that all of us, young or old, get to participate in this! To support the podcast and enjoy the bonus content for the episodes go here and then to bonus content. To connect with us, go here. For our free Read-A-Loud pdf book, click here. Happy Easter everyone!See omnystudio.com/listener for privacy information.

IN THIS EPISODE, YOU'LL LEARN: My true passion of marketing My favorite ways to market yourself & salon/spa/barber shop that actually work. & find your own way to make it work for you! Love this episode? SUBSCRIBE to never miss an episode on ⁠⁠⁠Spotify⁠⁠⁠ or ⁠⁠⁠Apple⁠⁠⁠! DON'T FORGET! Tell us your favorite parts of this episode and leave your rating! Follow on ⁠⁠⁠Facebook⁠⁠⁠ Follow on ⁠⁠⁠Instagram⁠⁠⁠ Never miss an announcement! Be a VIP ⁠⁠⁠HERE!⁠⁠

Outpouring Gates

In the very eighteenth episode of Bite-Sized, Ben and Jack Seijo discuss Twilight - Scene 18 (21:53-24:54)! They talk about menswear, hospitals, and the art of acting!We want to hear from you! Follow the show on social media (@bitesizedpod_ on Twitter, Instagram, and TikTok) or email myfavoritetwilightpodcast@gmail.com to join the conversation!

Reddit rSlash Storytime r relationships where I (28F) have been with my partner (38M) for 14 months and he still hides me on social media. Should I be worried? **Should I(33/f) Tell Everyone the Real Reason I Left My Husband(34/m) **I don't know how I feel about what my boyfriend asked me **Wife thinks I choose work over her because I won't call in on a whim **This girl i like doesn't want a relationship, even though everything we do suggests otherwise. What should I do? **Am I being ungrateful to leave a perfect guy? Can't feel anything anymore **It's my (F25) boyfriend (M29) and I's 7 year anniversary- am I being unreasonable? Should I tell my friend her boyfriend cheated? Hosted on Acast. See acast.com/privacy for more information.

We are excited to announce our Season 4 “Camp Fifi Uncensored” podcast launch with our 101st Episode, Part 2 drop with our guest, @ghizlaine_bennani.We've kick off Season 4 of our “Powerful Women” series with Ghizlaine Bennani who was born in Morocco became a student of Science taking her to Silicon Valley as an AI Scientist to becoming a Conscious Explorer, A Chief Operating Officer, Ted Talk Speaker, featured in Forbes and currently launching her “Limitless Girls of Morocco” program in Morocco based on her “Limitless Mind Academy” …and praying everyone there is alive and safe from the 6.8 magnitude earthquake they just had outside of Marrakech and felt from Casablanca to Portugal.As a Moroccan female Ghizlaine's vision and determination to become a spirited leader, I knew that I had met a like minded spirit who is invested in raising others (women) up around the world with her proven coaching formulas and practices per her lessons implemented into successful results!Ghizlaine believes we all have a purpose beyond what most of us are stepping into because of our programming and beliefs and what motivated Ghizlaine to create her coaching program, “Limited Mindless Academy.”Join me for our Part 2 conversation that is so authentic, relatable, expansive, delicious and lean in to what is possible for YOU when you take a moment to choose to shift uncomfortably for YOUR greater purpose!The “Camp Fifi Uncensored” podcast share individuals professional and personal life stories that offer value, are enlightening, offer individual's passion and purpose, entertain and create a massive desire to hear more!!Season 4 is HERE and we are so EXCITED to celebrate TOGETHER Episode 100 plus!!

We are excited to announce our Season 4 “Camp Fifi Uncensored” podcast launch with our 100th Episode, Part 1 drop!!!SUBSCRIBE, join and listen to our kick off episode of “Powerful Women” beginning with our extraordinary guest, Ghizlaine Bennani who is a former AI Scientist, Conscious Explorer, Ted Talk Speaker and Creator of the “Limitless Mindset Academy.”Ghizlaine is originally from Morocco.As a Moroccan female it takes extraordinary vision and determination to become a breakout star and when I connected with Ghizlaine through a “challenge” that combined Science and Spirituality and the Power of the Mind, all things I align and practice I knew that I had met a soulmate, a like minded spirit who truly was invested in raising others (women) up around the world with her proven coaching formulas and practices.Ghizlaine believes in other's value and power and that we all have a purpose beyond what most of us are stepping into because of our programming and beliefs.Ghizlaine has created her “Limited Mindless Academy” to help other's find their truth and manifest greatness in who we are here to live into and become one's true calling.Ghizlaine's program is based upon her education and professional and personal experiences witnessing others becoming Uber rich off of others who in turn are considered “disposable” everything that is against her and my belief systems and she consciously knew that the formula to happiness and purpose was greater than her successful career in Silicon Valley even while making an incredible amount of money beyond!Ghizlaine knew there was more than making her own incredible income and making others Uber wealthy and made a decision to step out of her “programming” to seek a higher purpose and help others do the same, become the best version of themselves that is valued as individuals they are, that they are seen, heard and valued with who their truth is because all deserve to be valued and need to align with those that truly stand for that cause.With the world at large there exists an unhealthy disconnect of systems currently in place with corporate greed and many people struggling because their contributions are not being valued and why we wanted to share Ghizlaine's vision and purpose on our podcast for our 100th episode kick off!Join me for our Part 1 conversation that is so authentic, relatable, expansive, delicious and lean in to what is possible for YOU when you take a moment to choose to shift uncomfortably for YOUR greater purpose!Click on one of the links below to listen on your favorite podcast platform!The “Camp Fifi Uncensored” podcast share individuals professional and personal life stories that offer value, are enlightening, offer individual's passion and purpose, entertain and create a massive desire to hear more!!Season 4 is HERE and we are so EXCITED to celebrate TOGETHER Episode 100!!

We first receive God's love, then share His love with everyone

Tell Everyone2 Timothy 4:1-5Come now, and let us reason together, says the Lord: though your sins be as scarlet, they shall be as white as snow; though they be red like crimson, they shall be as wool.” Isaiah 1:18.2 Timothy 4:1 In the presence of God and of Christ Jesus, who will judge the living and the dead, and in view of his appearing and his kingdom, I give you this charge: 2 Preach the wordProclaim the truth of Scripture as one who will be held accountable. 1 Timothy 4:13 Until I come, devote yourself to the public reading of Scripture, to preaching and to teaching.“be prepared in season and out of season”2. Be ready to preach the truth of Scripture.“Correct, rebuke and encourage—with great patience and careful instruction.  3. Preach the Scriptures with a broken heart.3 For the time will come when people will not put up with sound doctrine. Instead, to suit their own desires, they will gather around them a great number of teachers to say what their itching ears want to hear. 4 They will turn their ears away from the truth and turn aside to myths. 5 But you, keep your head in all situations, endure hardship, do the work of an evangelist, discharge all the duties of your ministry.4. We preach the Gospel in a hostile environment. “Preach the gospel, die, and be forgotten.” -- Zinzendorf 

Tell Everyone2 Timothy 4:1-5Come now, and let us reason together, says the Lord: though your sins be as scarlet, they shall be as white as snow; though they be red like crimson, they shall be as wool.” Isaiah 1:18.2 Timothy 4:1 In the presence of God and of Christ Jesus, who will judge the living and the dead, and in view of his appearing and his kingdom, I give you this charge: 2 Preach the wordProclaim the truth of Scripture as one who will be held accountable. 1 Timothy 4:13 Until I come, devote yourself to the public reading of Scripture, to preaching and to teaching.“be prepared in season and out of season”2. Be ready to preach the truth of Scripture.“Correct, rebuke and encourage—with great patience and careful instruction.  3. Preach the Scriptures with a broken heart.3 For the time will come when people will not put up with sound doctrine. Instead, to suit their own desires, they will gather around them a great number of teachers to say what their itching ears want to hear. 4 They will turn their ears away from the truth and turn aside to myths. 5 But you, keep your head in all situations, endure hardship, do the work of an evangelist, discharge all the duties of your ministry.4. We preach the Gospel in a hostile environment. “Preach the gospel, die, and be forgotten.” -- Zinzendorf 

Today is all about the headlines, Biden economic plane is to create and solve his own problems. California crushes bill that would allow for more severe punishment for child trafficking. See omnystudio.com/listener for privacy information.

The important aspect of healthy living starts with understanding the elements that your body requires.

Jamie was talking to Rico Leon from Rico to the Rescue on HGTV. Rico said his method of picking out good contractors is to figure out what their lie is. Everyone has one big lie and that lie tells Rico how good they are at their job. Jamie wants to know what everyone's big lie is.

On today's show, what's something that's overrated or underrated that you need to scream to the rooftops about?! For the whole podcast, as well as a ton of other exclusive perks, sign up to be a Fancy Idiot at FreeBeerAndHotWings.com! Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 162 – Interview with Topher, he's on a mission to tell everyone “God is good!”This is a powerful testimony of grit, perseverance, and true transformation.Most people know Christopher Trivette as “Topher”. He was born in Latvia, was abused at a young age, lost a third of his brain, and then acquired cerebral palsy. His parents dropped him off at an orphanage, and he was adopted by an American Christian family at the age of four. His adopted Mother was actually on a mission trip, handing out Bibles in honor of her grandfather's ministry, and ended up meeting Topher as a very young boy while visiting homes around the orphanage. God worked in a powerful way throughout that entire adoption process.Probably due to his upbringing and his abusive treatment at a young age, he became very rebellious toward his American adopted family members and others in the neighborhood and the schools. Because of his disruptive behaviors, Topher was sent at the age of eleven to a Christian boarding school, and sadly, that was the last time he lived with his American family on a full-time basis.As you'll hear in this episode, Topher expressed extreme bouts of anger. He recalls screaming out to God with the question, “Why me God?” At the age of twelve, he first learned what it meant to completely surrender his heart and to become a fully devoted follower of Christ. However, his mental mindset still corrupted his thinking, so he didn't fully surrender to the Lord until he was in his early twenties.Today, Topher is a powerful warrior for Christ and loves to share scriptures with anyone and everyone he encounters.Some of his favorite verses are Romans 12:2, and then he particularly loves 2nd Corinthians chapter 10 and verses 3 through 6. These are just a few he highlights during the interview.acourageousrecovery.com

Sometimes it's best to keep things to yourself because those who you tell things to might not support everything you do. --- Support this podcast: https://podcasters.spotify.com/pod/show/tmossboss/support

Relationship Reddit Stories, OP discovered that her husband was cheating on her so she decided to tell absolutely everyone.

Has Therapy Become the New Religion? Curt and Katie chat about op ed pieces from the New York Times, where there are a lot of opinions on what therapy is and should be. We explore comparisons of therapy to religion, the notion that going to therapy makes one good, safe and dateable, and how therapy seems to have invaded our lives.    Transcripts for this episode will be available at mtsgpodcast.com! In this podcast episode we talk about the opinion that therapy has become morally good Katie likes reading New York Times Op Ed pieces on what therapy is now. We decided to explore some of the questions these articles raise. What does the New York Times have to say about therapy and therapists? Going to therapy makes you a good person Putting that you're going to therapy on your dating app is a cheat code – meaning that you are safe to date We have reached a point where we're more focused on “mental health” than on mental illness Therapy-speak has invaded everything It is toxic to tell everyone to go to therapy What is leading to comparisons of therapy to religion? Decreased membership in organized religion Finding your own morals and values outside of organized religion Finding meaning and purpose through the work you do in therapy A fear of the degradation of social contracts and a rise of moral relativism How are people framing the role of the therapist? Potential for individual exploration of how to live one's life that is individualized and less tied to specific doctrine Another potential to be seen as giving direction on how to live life The role of community care versus individualized healing Relationship versus individual focus The nuance of what therapy is versus the fears of what is being done What is the fear about therapy being so central in our lives? The worry that people are too self-focused and not sufficiently other focused Pushing back on the status quo and established systems The notion that “therapy is good” and “all people need therapy” Therapy as a status symbol or a designation that I'm a good person Lack of access for folks with mental illness due to “worried well” and “personal growth” clients taking all of the spots Resources for Modern Therapists mentioned in this Podcast Episode: We've pulled together resources mentioned in this episode and put together some handy-dandy links. Please note that some of the links below may be affiliate links, so if you purchase after clicking below, we may get a little bit of cash in our pockets. We thank you in advance! New York Times' Articles: Why Do People Think Going to Therapy Makes You A Good Person? By Mychal Denzel Smith We Have Reached Peak ‘Mental Health' by Huw Green Is it Toxic to Tell Everyone to Get Therapy? By Zachary Siegel How the Language of Therapy Took Over Dating by Dani Blum The Problem with Letting Therapy-Speak Invade Everything by Tara Isabella Burton Our Linktree: https://linktr.ee/therapyreimagined Relevant Episodes of MTSG Podcast: Is Therapy an Opiate of the Masses? Navigating the Social Media Self-Diagnosis Trend Modern Therapist's Survival Guide Creative Credits: Voice Over by DW McCann https://www.facebook.com/McCannDW/ Music by Crystal Grooms Mangano https://groomsymusic.com/

When Jesus started His earthly ministry at 30, His teachings were very focused on His mission. He repeated those teachings over and over again, and He modeled those teachings for His followers. In this mini-series, we'll explore the core teachings of Jesus and how those teachings should apply to our lives.

When Jesus started His earthly ministry at 30, His teachings were very focused on His mission. He repeated those teachings over and over again, and He modeled those teachings for His followers. In this mini-series, we'll explore the core teachings of Jesus and how those teachings should apply to our lives.

This week Dan and Andrew “go for it” and discuss the Crime in Stereo record I Was Trying to Describe You to Someone. We talk about: Andrew getting Adnan released, the cultural differences in condiment sharing, non traditional pizza styles, simping for the monarchy, the social aspect of LinkedIn, Slack chat personalities, Dan gets a bad coffee, Hoagie Haven sells out, the definition of “Going for It”, music business critiques, Daytrader vs Daybreaker, and indie artists making mainstream rock records. Listen Everywhere. Tell Everyone. // Follow us at @danbassini, @mysprocalledlife, and @runintotheground. Listen to our RITG Mixtape Vol. 9 here and our Best of RITG playlist here.

This week we have New Jersey punk show legend Joe Pulito on to talk about the Bouncing Souls masterpiece How I Spent My Summer Vacation. We talk about booking VFW's as a teenager, infamous local shows, show flyer vibes, adolescent punk socialization, teenage bands as entrepreneurs, the rise and fall if Asbury Lanes, Joe forgets his anniversary, shore town gentrification, Chris Gethard as the patron saint of New Jersey, the pandemic and the music industry, a quick “New Jersey punk” google search, “Manthem” as social critique, bringing your kids to shows, the Trocadero Theater, and leaving “Blazer Punks” behind. Listen everywhere. Tell Everyone. // Follow us at @danbassini, @mysprocalledlife, @joepulito and @runintotheground. Listen to our RITG Mixtape Vol. 9 here and our Best of RITG playlist here.

We are commanded to be a light to everyone so that God would get glory. Are we hiding our light under the basket of fear, worries, doubts? OR are we shining brightly - exposing the darkness? How do we handle being afraid of people's hatred towards the Gospel and us as Christians? Let's talk about it. KEY VERSES: 1 Thessalonians 1 and Matthew 5:6

JOIN THE FAMILY@ https://qaraahfilms.com https://qaraahfilmsmerch.com

JOIN THE FAMILY@ https://qaraahfilms.com https://qaraahfilmsmerch.com

TELL EVERYONE - New mom chat - Kali's article and twitter      - https://www.insider.com/my-child-diagnosed-rare-genetic-condition-syngap1-2022-6       - https://twitter.com/WorthKali - Tavillas: https://syngap.fund/susan (6/22/15)   CHECK OUT THIS CONFERENCE: https://syngap.fund/treat   DRUG CO NEWS - Anglemans and Ionis! https://www.prnewswire.com/news-releases/ionis-treatment-for-angelman-syndrome-receives-orphan-drug-and-rare-pediatric-disease-designations-from-us-fda-301566169.html  - Praxis update: At the end, scroll down.    CIITIZEN - Webinar was awesome https://syngap.fund/virginie - Sign up! https://www.ciitizen.com/syngap1/   PROBABLY GENETIC IS WORKING! - Assessment:  syngap.fund/maybe - https://symptom-checker.probablygenetic.com/syngap/  - Webinar: https://syngap.fund/PG  - Sponsored testing with Mahzi! https://mahzi.com/    REMEMBER NOT TO MISS  - June 2022 https://mailchi.mp/syngapresearchfund.org/june22   - Sign up for the EF Panel: https://bit.ly/efmen      FUNDRAISERS - MDBR: Join us and secure $30k matching funds https://syngap.fund/SRFMDBR22   - MICE: Help us Make 2!  https://syngap.fund/2mice    EVENTS - June 25 in DFW - Join us for a family meeting and hear from Dr. Perry.  Link soon. - September 12-14 in San Diego - #GlobalGenes Meeting.  Link soon. - October 8 in NJ - Caren Leib Gala https://www.syngapresearchfund.org/get-involved/fundraising/caren-leib-gala  - October 8 in SC - Scramble for SYNGAP https://www.syngapresearchfund.org/get-involved/fundraising/scramble-for-syngap   - November 12 in GA - Sparks of Hope Gala https://syngap.fund/soiree  - December 1 in TN - Syngap Science Meeting - https://syngap.fund/treat    This is a podcast: subscribe to and rate this 10 minute #podcast #SYNGAP10 here https://www.syngapresearchfund.org/syngap10-podcast   Apple podcasts: https://podcasts.apple.com/us/podcast/syngap10-weekly-10-minute-updates-on-syngap1-video/id1560389818    Episode 64 of #Syngap10 - June 14, 2022 #F78A1 #Syngap #epilepsy #autism #intellectualdisability #id #anxiety #raredisease #epilepsyawareness #autismawareness #rarediseaseresearch #SynGAPResearchFund #CareAboutRare #PatientAdvocacy #GCchat #Neurology #GlobalCollaboration #EpilepsyFoundation #Praxis #ProbablyGenetic #Mahzi   Copy from letter from Praxis: Monday morning, June 6th, we published an 8K filing announcing news involving multiple programs at Praxis Precision Medicines. One of these announcements pertained to the FDA's clinical hold on our recent IND filing for PRAX-222 in SCN2A, so we wanted to share further context for it. On May 25, 2022, the Company received a communication from the U.S. Food and Drug Administration (the “FDA”) providing additional information on the clinical hold placed on the Company's Investigational New Drug application (the “IND”) for the study of PRAX-222, an antisense oligonucleotide, for the treatment of patients with SCN2A gain-of-function mutations. The communication indicated that our IND could be cleared once we submit additional documentation related to the preclinical non-human primate toxicology study that supports the proposed starting dose in the clinical study. We're requesting a Type A meeting with the FDA to confirm the study design and further clarify the requirements for dose escalation beyond the starting dose. This surely will leave our SCN2A community with questions about the timing of our path forward. While the protocol and the discussions being held with the FDA remain confidential, we will do our best to maintain transparency and responsiveness throughout the process.     We continue to be fully committed to advancing PRAX-222 to clinical study. We also want to restate that this news is specific to PRAX-222, without impact on our PRAX-562 program for SCN2A, SCN8A and TSC. In Monday's press release, we reiterated our focus on driving toward proof of concept for PRAX-562. We'll provide further updates on PRAX-562 as we approach major milestones on this path. In addition, our other programs in PCDH19 and SYNGAP1 remain on-track.     Beyond epilepsy, Monday's 8K filing announced significant news pertaining to our Aria study of PRAX-114 in Major Depressive Disorder (MDD). It is with great regret that we announce the failure of the Aria Study, a study to determine the efficacy of a GABBA PAM extrasynaptic preference medicine to achieve fast-acting, lasting reduction of symptoms of MDD. After reviewing the data and our operational controls and observing failure to achieve our primary endpoint, we determined that PRAX-114 was indeed safe but not efficacious, and no further research and development of PRAX-114 is warranted. This conclusion has a negative impact on the study of PRAX-114 to treat Post-Traumatic Stress Disorder and Essential Tremor. This is a difficult decision for the Praxis team; but our commitment and capacity to researching and developing genetic insight-based treatments for people living with disorders of the CNS is in no way diminished.

Throw the doors open, build your team, tell everyone. #S10e64 TELL EVERYONE - New mom chat - Kali's article and twitter - https://www.insider.com/my-child-diagnosed-rare-genetic-condition-syngap1-2022-6 - https://twitter.com/WorthKali - Tavillas: https://syngap.fund/susan (6/22/15) CHECK OUT THIS CONFERENCE: https://syngap.fund/treat DRUG CO NEWS - Anglemans and Ionis! https://www.prnewswire.com/news-releases/ionis-treatment-for-angelman-syndrome-receives-orphan-drug-and-rare-pediatric-disease-designations-from-us-fda-301566169.html - Praxis update: At the end, scroll down. CIITIZEN - Webinar was awesome https://syngap.fund/virginie - Sign up! https://www.ciitizen.com/syngap1/ PROBABLY GENETIC IS WORKING! - Assessment: syngap.fund/maybe - https://symptom-checker.probablygenetic.com/syngap/ - Webinar: https://syngap.fund/PG - Sponsored testing with Mahzi! https://mahzi.com/ REMEMBER NOT TO MISS - June 2022 https://mailchi.mp/syngapresearchfund.org/june22 - Sign up for the EF Panel: https://bit.ly/efmen FUNDRAISERS - MDBR: Join us and secure $30k matching funds https://syngap.fund/SRFMDBR22 - MICE: Help us Make 2! https://syngap.fund/2mice EVENTS - June 25 in DFW - Join us for a family meeting and hear from Dr. Perry. Link soon. - September 12-14 in San Diego - #GlobalGenes Meeting. Link soon. - October 8 in NJ - Caren Leib Gala https://www.syngapresearchfund.org/get-involved/fundraising/caren-leib-gala - October 8 in SC - Scramble for SYNGAP https://www.syngapresearchfund.org/get-involved/fundraising/scramble-for-syngap - November 12 in GA - Sparks of Hope Gala https://syngap.fund/soiree - December 1 in TN - Syngap Science Meeting - https://syngap.fund/treat This is a podcast: subscribe to and rate this 10 minute #podcast #SYNGAP10 here https://www.syngapresearchfund.org/syngap10-podcast Apple podcasts: https://podcasts.apple.com/us/podcast/syngap10-weekly-10-minute-updates-on-syngap1-video/id1560389818 Episode 64 of #Syngap10 - June 14, 2022 #F78A1 #Syngap #epilepsy #autism #intellectualdisability #id #anxiety #raredisease #epilepsyawareness #autismawareness #rarediseaseresearch #SynGAPResearchFund #CareAboutRare #PatientAdvocacy #GCchat #Neurology #GlobalCollaboration #EpilepsyFoundation #Praxis #ProbablyGenetic #Mahzi Copy from letter from Praxis: Monday morning, June 6th, we published an 8K filing announcing news involving multiple programs at Praxis Precision Medicines. One of these announcements pertained to the FDA's clinical hold on our recent IND filing for PRAX-222 in SCN2A, so we wanted to share further context for it. On May 25, 2022, the Company received a communication from the U.S. Food and Drug Administration (the “FDA”) providing additional information on the clinical hold placed on the Company's Investigational New Drug application (the “IND”) for the study of PRAX-222, an antisense oligonucleotide, for the treatment of patients with SCN2A gain-of-function mutations. The communication indicated that our IND could be cleared once we submit additional documentation related to the preclinical non-human primate toxicology study that supports the proposed starting dose in the clinical study. We're requesting a Type A meeting with the FDA to confirm the study design and further clarify the requirements for dose escalation beyond the starting dose. This surely will leave our SCN2A community with questions about the timing of our path forward. While the protocol and the discussions being held with the FDA remain confidential, we will do our best to maintain transparency and responsiveness throughout the process. We continue to be fully committed to advancing PRAX-222 to clinical study. We also want to restate that this news is specific to PRAX-222, without impact on our PRAX-562 program for SCN2A, SCN8A and TSC. In Monday's press release, we reiterated our focus on driving toward proof of concept for PRAX-562. We'll provide further updates on PRAX-562 as we approach m --- Send in a voice message: https://podcasters.spotify.com/pod/show/syngap10/message

It doesn't matter if you're the best in the world in what you do if no one knows about it. Marketing is a simple concept; decide how you want people to view your business or brand, and tell them. In today's episode, Chris Hollis with Pure Marketing chats with Alex about the first steps to telling your businesses story and practically how to get the word out.   Check out Pure Marketing at www.PureMarketingTeam.com.  

For St. Patrick's Day, Maeve Higgins, comedian and the author of Tell Everyone on This Train I Love Them (Penguin Books, 2022), talks about the Irish immigrants -- and Irish-Americans of today. Then WNYC's Gwynne Hogan, live from the parade, which is taking place for the first time in three years.