Podcasts about TSC

#849: Join Lauryn Bosstick as she sits down to share her 10 must-have pregnancy products she swears by! This ultimate pregnancy survival kit features her ride-or-die essentials getting her through her third pregnancy. In this episode, Lauryn reveals her favorite products to help her unwind, how she manages her growing to-do list, & her top tips for staying comfortable when things start to feel anything but.   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Lauryn Bosstick click HERE   Read More on The Skinny Confidential HERE   Head to our ShopMy page HERE and LTK page HERE to find all of the products mentioned in each episode.   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is sponsored by Ritual  Visit ritual.com/skinny for 40% off your first purchase.   This episode is sponsored by BUMPSUIT To Shop the Lauryn Bosstick x Bumpsuit Collection visit bit.ly/BUMPSUITXLB and use code SKINNY for 15% off for a limited time.    This episode is sponsored by Simply Pop  Sip on the juicy side of life. Find out where you can try Simply Pop at cokeurl.com/simplyPOP!   This episode is sponsored by iRestore Unlock your best skin with iRestore and HUGE savings on the iRestore Illumina Face Mask with code SKINNY at irestore.com/SKINNY!   This episode is sponsored by Bobbie  Bobbie is offering an additional 10% off on your purchase with the code TSC. Visit hibobbie.com to find the Bobbie formula that fits your journey.   This episode is sponsored by Branch Basics Shop Branch Basics in 600+ Target stores nationwide, or Target.com. You can also use the code SKINNY15 to get 15% off at branchbasics.com/SKINNY15.    Produced by Dear Media

#847: Join us as we sit down with Dave Asprey – entrepreneur, best-selling author, & biohacking advocate, widely recognized as a leading figure in the biohacking movement. Often referred to as “The Father of Biohacking”, Dave has dedicated decades of his career to enhancing human performance, longevity, & optimal health. In this episode, Dave explores the connection between diet & disease risk, how your environment shapes your biology, the role of light exposure in sleep quality, methods to enhance sexual health, & how childhood trauma impacts overall well-being. Plus, Dave reveals the surprising truth about what's really in your coffee & how to shift your mindset in meditation!   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Dave Asprey click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Head to our ShopMy page HERE and LTK page HERE to find all of the products mentioned in each episode.   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   To Order Dave Asprey's new book, Heavily Medicated visit daveasprey.com/heavily-meditated.   To Shop Danger Coffee visit dangercoffee.com/SKINNY and use code SKINNY for 10% off your first time purchase.    To Shop TrueDark visit bit.ly/TD-SKINNY and use code SKINNY for 10% off your first time purchase.    This episode is sponsored by The Skinny Confidential Shop the Memorial Day Sale at ShopSkinnyConfidential.com and take 20% off your favorite TSC Products – for a limited time only.   This episode is sponsored by Cymbiotika Hurry to Cymbiotika.com/TSC to get 25% off.    This episode is sponsored by OSEA Get 10% off your first order sitewide with code SKINNY at OSEAMalibu.com.   This episode is sponsored by Squarespace Go to Squarespace.com for a free trial, and when you're ready to launch, squarespace.com/SKINNY to save 10% off your first purchase of a website or domain.   This episode is sponsored by Nowadays Nowadays is easy to purchase, with direct-to-door delivery. Must be 21 to order at trynowadays.com.   This episode is sponsored by Miami Convention & Visitors Bureau Visit FindYourMiami.com.   This episode is sponsored by Mizzen + Main Go to Mizzenandmain.com and use promo code SKINNY20 to get 20% off your first purchase.   Produced by Dear Media  

#846: Join Lauryn as she sits down to talk about all things pregnancy! As she prepares for baby number three, Lauryn gets real & honest about her pregnancy wellness journey & breaks down the daily routines she swears by. From mediation practices & red light therapy for hormonal acne, to her supplement stack featuring her must-have prenatal, plus her top tips for staying stylish while embracing comfort.   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Lauryn Bosstick click HERE   Read More on The Skinny Confidential HERE   Head to our ShopMy page HERE and LTK page HERE to find all of the products mentioned in each episode.   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is sponsored by Ritual Visit ritual.com/skinny for 40% off your first purchase.   This episode is sponsored by The Skinny Confidential Shop the Memorial Day Sale at ShopSkinnyConfidential.com and take 20% off your favorite TSC Products – for a limited time only.   This episode is sponsored by Square Get up to $200 off Square hardware when you sign up at square.com/go/skinny!   This episode is sponsored by Bobbie Exclusively for our TSC listeners, Bobbie is offering an additional 10% off on your purchase with the code skinny. Visit hibobbie.com for more details.   Produced by Dear Media

Meet Amanda Chagnon, mom to three beautiful boys including her youngest, Alexios, who has medical complexities due to a condition called Tuberous Sclerosis Complex. Tuberous sclerosis complex (TSC) is a rare genetic disease that causes non-cancerous tumors or lesions to grow in the brain and other areas of the body, including the eyes, lung, heart, kidneys, and skin. Amanda shares how motherhood and her nursing background have intertwined, and the blessings and difficulties of homeschooling, especially when caring for a medically complex child. Honest about her struggles, other caregivers may find this conversation refreshing and learn from the ways she has found to manage her internal and external struggles.

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "Refining TSC Care: Phenotyping, Clustering, and Clinical Impact," Ajay Gupta, MD, director of the Tuberous Sclerosis Program at Cleveland Clinic, discusses recently published research that used unsupervised clustering to group over 900 patients with tuberous sclerosis complex (TSC) into four clinically meaningful phenotypic clusters. He outlines the distinct traits of each cluster—ranging from tumor risk to cognitive impairment—and explains how variant-specific genetic data helped reinforce these categories. Gupta, who also serves as a professor of neurology at the Cleveland Clinic Lerner School of Medicine, also explores the clinical value of these findings for surveillance planning, early intervention, and future therapeutic trials. He emphasizes that while overlap between clusters exists, this approach lays essential groundwork for precision care and more targeted research in TSC. Looking for more epilpesy discussion? Check out the NeurologyLive® Epilepsy clinical focus page. Episode Breakdown: 1:00 – Study goals and the shift from genotype-to-phenotype toward phenotype-to-genotype mapping 2:40– Overview of the 4 main phenotypic clusters identified in the TSC population 8:05 – Genetic domain associations and their impact on clinical monitoring and treatment 11:50 – Neurology News Minute 14:45 – Understanding overlap between clusters and avoiding overprediction in clinical settings 17:00 – Implications for future surveillance strategies and precision candidate selection in TSC trials The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA AdComm Plans to Review Investigational Cell Therapy Deramiocel for DMD Cardiomyopathy Gene Therapy AAV-GAD Gains Regenerative Medicine Advanced Therapy Designation as Potential Parkinson Treatment Microbiome-Targeting Therapy MaaT033 Continues to Show Promise in Final Phase 1 Readout Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

#842: Join us as we sit down with the hosts of SHE MD  – world renowned OBGYN Dr. Thaïs Aliabadi, “Dr. A,” & women's advocate and influencer, Mary Alice Haney. This powerhouse duo brings unfiltered, impactful conversations to the SHE MD podcast with celebrity guests & today's top experts, covering essential women's health topics like menopause, PCOS, endometriosis, & fertility – on a mission to empower women with the knowledge & tools they need to become their own best health advocates. In this episode, Dr. A & Mary Alice take a deep dive into the challenges & implications of PCOS & endometriosis, highlight the importance of early mammogram screenings, & create a roadmap for women struggling with health issues.They also break down the growing conversation around weight loss medications such as ozempic & provide actionable early detection resources for breast cancer & PCOS – continuing their mission to drive awareness, education, & advocacy in women's health!   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with SHE MD click HERE   To connect with Dr. Thaïs Aliabadi click HERE   To connect with Mary Alice Haney click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   To learn more about SHE MD and take their risk assessment tests visit shemdpodcast.com.   Join us on May 17th in Los Angeles for The Dear Media Edit, a live wellness experience with your favorite hosts and top voices in health and wellness—tickets available now at DearMedia.com/events.   This episode is sponsored by SmartMouth Find SmartMouth at Walgreens, Walmart, Amazon or visit smartmouth.com/skinny to snag a special discount on your next SmartMouth purchase.   This episode is sponsored by Squarespace Go to Squarespace.com for a free trial, and when you're ready to launch, squarespace.com/SKINNY to save 10% off your first purchase of a website or domain.   This episode is sponsored by Cymbioktika Go to Cymbiotika.com/TSC to get 20% off plus free shipping.    This episode is sponsored by Just Thrive Go to JustThrive.com and use code TSC for 20% off your first order.   This episode is sponsored by Fatty15 Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/SKINNY and using code SKINNY at checkout.   This episode is sponsored by Spritz Society Spritz Society is now available everywhere! Head to spritzsociety.com to find a store near you, and make sure to follow @spritz on Instagram for all their latest announcements and upcoming events. Spritz Society, Summer Starts Here!   Produced by Dear Media

An end to the ‘boom and bust' of contracts for rail suppliers? Sir Andrew Haines, Network Rail CEO, describes the Rail Enhancement Pipeline as a ‘flawed proposition' because it is ‘owned politically' and is ‘not a strategy for the railway'. We ask - is he right?You can now apply to become a train driver at 18! But will it solve the railway's shortage of drivers?And Network Rail apparently spends £10k a WEEK on internal flights! But is that the real story?In this episode:(00:00) Intro(01:20) ‘Boom and Bust' on the railway? Haines at the TSC(24:06) Interview with RIA about boom and bust(33:01) Train driver minimum age now 18(38:00) Interview with train driver Bessie Matthews(46:01) News about a railway party(47:53) Thanks to Supporters(49:04) Railway News Round-up(49:06) HS2 Bromford tunnel bore completed(50:06) Network Rail spends £10k a week on internal flights(52:40) Nationalisation date for Greater Anglia(53:44) Solar panels for between railway tracks(55:47) UK to Switzerland by high speed train?(57:29) The Quiz(59:29) Lego replica of Forth BridgeMembership: If you want to see even more from Green Signals, including exclusive content, become a member and support the channel further too.YouTube -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@GreenSignals/join⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Patreon -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/GreenSignals⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Green Signals: Website -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.greensignals.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Merchandise - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://greensignals.etsy.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Newsletter -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.greensignals.org/#mailing-list⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow: X (Twitter) -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/greensignallers⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LinkedIn -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/company/green-signals-productions-ltd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://instagram.com/greensignallers⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Credits:Thumbnail image - Network Rail

#839: Join us as we sit down with Kendra Wilkinson – a television personality, model, & author. Kendra first captured the spotlight on the hit reality show The Girls Next Door, which showcased life inside the Playboy Mansion. She later starred in her own successful series, Kendra and Kendra On Top, chronicling both her personal & professional evolution. In this episode, Kendra opens up about her experience as one of Hugh Hefner's girlfriends, the truth behind life at the Mansion, her journey into marriage & motherhood, & how she's learned to embrace her true, authentic self as the iconic Kendra Wilkinson! To Watch the Show click HERE For Detailed Show Notes visit TSCPODCAST.COM To connect with Kendra Wilkinson click HERE To connect with Lauryn Bosstick click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194. This episode is brought to you by The Skinny Confidential Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes. Visit http://istandwithmypack.org/ to support I Stand With My Pack's (ISWMP) mission by donating or adopting. Every contribution helps! This episode is sponsored by ARMRA Go to tryarmra.com/SKINNY or enter SKINNY to get 15% off your first order. This episode is sponsored by Cymbioktika Go to Cymbiotika.com/TSC to get 20% off plus free shipping.  This episode is sponsored by Fatty15  Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/SKINNY and using code SKINNY at checkout. This episode is sponsored by Caraway Visit Carawayhome.com/THESKINNY10 to take an additional 10% off your next purchase. This episode is sponsored by Branch Basics Use code SKINNY15 to get 15% off at branchbasics.com/SKINNY15.  This episode is sponsored by Ritual Get 25% off your first month for a limited time at ritual.com/SKINNY. Produced by Dear Media  

#837: Join us as we sit down with Mike Feldstein – founder of Jaspr. After years in the wildfire & flood restoration sector, as well as air quality consulting, Mike witnessed firsthand how polluted air can severely impact our health. Frustrated by the lack of truly effective air purifiers on the market, he set out to create his own solution – Jaspr. In this episode, Mike shares how the LA wildfires affected air quality, gives practical tips to detox the air in your home, reveals the hidden truth of mold toxicity, & dives into why purifying your air is more important than ever!    To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Jaspr click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   Visit jaspr.co/skinny to learn more and use code SKINNY for $400 off your Jaspr purchase!    To learn more about Kindling Academy visit kindling.academy.   Visit istandwithmypack.org to support I Stand With My Pack's (ISWMP) mission by donating or adopting. Every contribution helps!   This episode is sponsored by ASTRAL House Marg Summer is here. Time to stock up! Go to astraltequila.com to find Astral near you - and don't forget the limes! Please Enjoy Responsibly.    This episode is sponsored by BetterHelp Visit BetterHelp.com/SKINNY to get 10% off your first month.   This episode is sponsored by Cymbiotika Go to Cymbiotika.com/TSC to get 20% off plus free shipping.    Produced by Dear Media

Tim Irnich from SUSE shares his work with Edge computing, focusing on the telecommunications industry. He highlights the importance of standardization and interoperability across the industry, specifically focusing on the widespread adoption of Linux and Kubernetes. Tim also elaborates on Project Sylva, an initiative under the Linux Foundation, aimed at creating a standardized stack for the European telco operators. We also discuss challenges and opportunities presented by the vast array of open source projects within the CNCF landscape and the potential for AI to enhance network efficiency and reliability. The episode provides a comprehensive look into the collaborative efforts and technological advancements shaping the telecom sector. 00:00 Welcome 01:14 Open Source Adoption in the Telco Industry 02:14 Challenges and Standardization in Telco Networks 04:35 Curating Reliable Stacks for Telco 06:11 Project Silva: An Open Source Initiative 18:55 AI in the Telecom Industry 22:11 Conclusion and Final Thoughts   Tim Irnich is the product manager for SUSE Edge for Telco, an open source based horizontal telco cloud solution. He is also a member of the Board of Directors at the LF Europe Sylva Project. Tim has been active in telco related open source communities such as LF Networking, OPNFV, OpenDaylight, OpenStack/OpenInfra for over a decade and held positions on several committees including the LFN TAC, TSC and Board of Directors in OPNFV and OpenDaylight. Before joining SUSE in 2018, Tim worked at Ericsson, where he ran the open source and ecosystem program for Ericsson's cloud business unit and helped found Ericsson's open source development arm that is today known as Ericsson Software Technologies. 

In Season 10, Episode 16 of the Remarkable Retail Podcast, hosts Michael LeBlanc and Steve Dennis open with a deep dive into the latest turbulence in the retail world. They tackle the U.S. administration's wobbly trade policies, slowing home sale, and rising inventory risks stemming from ongoing tariffs. They also dissect challenges facing the luxury sector, with Kering posting disappointing numbers and growing concerns around the Saks/Neiman Marcus deal amid financial instability. Meanwhile, Barnes & Noble bucks the trend, announcing 60 new stores in 2025, reinforcing that physical retail remains far from dead.The second half of the episode features a compelling live interview from Shoptalk in Las Vegas with Neil Tenzer, Vice President, Customer Loyalty, Insights and Engagement at Tractor Supply Company (TSC). Neil provides a masterclass in building a robust loyalty program with real impact. He shares his unique journey—from a Nordstrom associate to a strategy consultant to a senior executive at TSC—and how these experiences shape his approach to customer engagement.Neil walks through the evolution of Tractor Supply's Neighbors Club, which now boasts over 39 million members and accounts for 80% of company revenue. He highlights how spending time on customers' properties—understanding their lives firsthand—informs everything from reward program design to personalization strategy. Neil also discusses how TSC thinks differently about loyalty economics: rather than banking on reward breakage, they aim for full reward utilization to deepen customer engagement.Listeners get a firsthand look at TSC's approach to micro-segmentation, omnichannel loyalty, and personalization efforts that bridge online and in-store experiences. Neil offers insights into experimental tactics, the application of agentic AI for personalization, and the cultural commitment at TSC to putting the customer first—literally in every loyalty and personalization decision. The episode closes with Neil's advice to fellow retailers. About NeilNeil Tenzer is Vice President of Customer Loyalty, Insights & Engagement at Tractor Supply Co. where he is privileged to lead the Neighbor's Club - one of the largest and fastest growing loyalty programs in retail! With 38+ M members and $12+ B in sales, the program leverages robust analytics and data science to connect each customer with the most compelling marketing and uniquely relevant offers. Neil has 20 years of experience employing data and analytics to lead multinational organizations through growth and turnaround strategy across the healthcare, consumer, and retail spaces. Neil holds a Bachelor's Degree in Business Economics from Indiana University and an MBA from the University of Oxford. About UsSteve Dennis is a strategic advisor and keynote speaker focused on growth and innovation, who has also been named one of the world's top retail influencers. He is the bestselling authro of two books: Leaders Leap: Transforming Your Company at the Speed of Disruption and Remarkable Retail: How To Win & Keep Customers in the Age of Disruption. Steve regularly shares his insights in his role as a Forbes senior retail contributor and on social media.Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and now, media entrepreneur. He has been on the front lines of retail industry change for his entire career. Michael has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Marketing conference with leaders from Walmart & Google. He brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, CanWest Media, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice.Michael produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in America, Remarkable Retail with his partner, Dallas-based best-selling author Steve Dennis; Canada's top retail industry podcast The Voice of Retail and Canada's top food industry and one of the top Canadian-produced management independent podcasts in the country, The Food Professor with Dr. Sylvain Charlebois from Dalhousie University in Halifax.Rethink Retail has recognized Michael as one of the top global retail experts for the fourth year in a row, Thinkers 360 has named him on of the Top 50 global thought leaders in retail, RTIH has named him a top 100 global though leader in retail technology and Coresight Research has named Michael a Retail AI Influencer. If you are a BBQ fan, you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok.Michael is available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state and future of the retail industry in North America and around the world.

#833: Join us as we sit down with Dean Graziosi – entrepreneur, New York Times bestselling author, investor, co-founder of mastermind.com, & one of the most sought-after success & mindset coaches in the world. For over two decades, Dean has been on a mission to help millions break free from the traditional path, shift their mindset, & build thriving businesses rooted in what they already know. In this episode, Dean unlocks the success playbook that schools never taught you – from the transformative power of giving, to building a positive mindset that fuels resilience, how to cultivate optimism, the importance of taking action, & insights on how you can Thrive in 2025! Visit thrive350.com to attend the FREE ‘Thrive in 2025' 3-day virtual live event featuring Dean Graziosi, Tony Robbins, & more!   To Watch the Show click HERE   To Listen to episode #314 ‘Dean Graziosi On The Power Of Mindset To Build Inner Strength, Confidence, & Overcome Obstacles' click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Dean Graziosi click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   This episode is sponsored by The Skinny Confidential Refresh your routine. Shop The Skinny Confidential Anniversary Sale at shopskinnyconfidential.com from April 22nd - April 25th for 30% off SITEWIDE!   This episode is sponsored by Cymbiotika Claim 20% off and free shipping at Cymbiotika.com/TSC.    This episode is sponsored by Jolie Head to jolieskinco.com/SKINNY to try it out for yourself with FREE shipping.   This episode is sponsored by YSL Beauty Shop all 9 dreamy shades of YSL Loveshine Plumping Lip Oil Gloss now at Sephora.   This episode is sponsored by OSEA Head to OSEAmalibu.com and use code SKINNY for 10% off your first order sitewide.   This episode is sponsored by SAKS Shop SAKS.com.   This episode is sponsored by Fatty15 Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/SKINNY and use code SKINNY at checkout.   Produced by Dear Media

#830: Join us as we sit down with Sami Clarke & Sami Spalter – founders of FORM & hosts of TransFORM. Fueled by their personal journeys in health & wellness, these two powerhouse women came together with a mission to help others unlock their fullest potential & feel their absolute best. Inspired by this purpose, they founded FORM – an all-in-one destination for fitness, wellness, & self-love. FORM is designed to support you every step of the way, offering everything from on-demand workouts and expert-led programs to nourishing recipes & tools that help you feel your best – inside and out! In this episode, both Sami's open up about their most transformative wellness practices, how movement became their medicine, the power of embracing change, & how they continue to evolve through every season of life!   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with FORM click HERE   To connect with Sami Clarke click HERE   To connect with Sami Spalter click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   Visit istandwithmypack.org to support I Stand With My Pack's (ISWMP) mission by donating or adopting. Every contribution helps!   This episode is sponsored by Just Thrive   Visit JustThriveHealth.com and use code SKINNY90 for 20% off your first 90 day bottle. That's like getting a month for free!   This episode is sponsored by NOBULL   Visit nobullproject.com/tsc for 30% off your entire order.   This episode is sponsored by Cymbiotika   Claim 20% off and free shipping at Cymbiotika.com/TSC.    This episode is sponsored by Hiya Health   Go to hiyahealth.com/SKINNY to receive 50% off your first order.    This episode is sponsored by Addyi    Learn more at Addyi.com.   This episode is sponsored by Square    Get up to $200 off Square hardware when you sign up at square.com/go/skinny.    This episode is sponsored by The Skinny Confidential   Refresh your routine. Shop The Skinny Confidential Anniversary Sale at shopskinnyconfidential.com from April 22nd - April 25th for 30% off SITEWIDE!   Produced by Dear Media

In the first episode of TSC Now in 2025, host Dan Klein tackles the challenging topic of what happens when a clinical trial fails and how failed clinical trials inform future research in tuberous sclerosis complex (TSC). Dan interviews Mary Kay Koenig, MD, Professor of Child Neurology and Associate Vice Chair for Clinical Research at … Continue reading Episode 50: What happens when a clinical trial fails? →

Send us a textFeeling stuck and staring at a blinking cursor? You're not alone.In this episode of Coffees and Content, I'm sharing 5 overlooked places every business owner should be mining for content ideas - even when you feel like you've posted everything already.Whether you're a coach, service provider, or small business owner trying to stay consistent online, this episode will show you exactly where to look when the inspiration well feels dry. From your own inbox to your testimonials, I'm walking you through content gold that's hiding in plain sight - and how to turn it into scroll-stopping posts, podcast episodes, or Reels.

Savanna and Tyler are joined by Eduardo Perez, the genius Chief Science Officer behind Epicutis Skincare! From the roots of chia seeds and collagen-saving magic to groundbreaking studies on TSC and retinoids, they're spilling the sciencey tea. They dive deep into why Lipid Serum is basically liquid ibuprofen for your face, the truth about skincare innovation, and what's next for Epicutis (spoiler: new launch incoming

Facial recognition has become common for personal mobile devices, relying on our unique biological features for security and access control. However, the technology is still somewhat controversial in the broader business world. Terry Schulenburg with CyberLink, makers of FaceMe, will help us understand the technology, how the controversy is mainly manufactured by film/TV, and the opportunity for solution providers. What industries are embracing it? What is the liability for those who sell it?    Learn More about FaceMe during Terry's appearance on ISVs on Tap!   Around the Nation: Register for TSC's RFID Encoding Webinar   #VARValue - How does facial recognition technology fit alongside the solutions VARs are already selling? When should they engage the CyberLink team, and how will they help you win opportunities?   On Our Radar Terry - AI in Hollywood Dean - Bluetooth security issues John - Who is your doctor taking money from?   Keep in Touch! Email – nation@bluestarinc.com LinkedIn - https://www.linkedin.com/company/blue-star Subscribe to the BlueStar Nation Newsletter - https://nation.bluestarinc.com/#subscribe    Sponsored by: Elo Outdoor Kiosk Solutions

#824: Join us as we sit down with Brigham Buhler – healthcare entrepreneur on a mission to revolutionize America's broken system. As a founder of Ways2Well, owner of Revive Rx Pharmacy & Bioreach, Brigham is challenging the status quo with a healthcare model that prioritizes patients over profits through preventative care, transparency, & innovation. In this episode, Brigham pulls back the curtain on the corruption within the American healthcare system, exposing the truth behind the opioid crisis, misleading antidepressant prescriptions, & the hidden tactics of insurance companies. Get ready for this episode as we get real about what is really happening in the healthcare system & uncover secrets that they don't want you to know! To Watch the Show click HERE For Detailed Show Notes visit TSCPODCAST.COM To connect with Brigham Buhler click HERE To connect with Ways2Well click HERE To connect with Lauryn Bosstick click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194. To learn more about Ways2Well visit ways2well.com and use code skinny for 10% off the product line.  This episode is brought to you by The Skinny Confidential Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes. This episode is sponsored by Cymbiotika Go to Cymbiotika.com/TSC for 20% off + free shipping. This episode is sponsored by Live Conscious Visit weliveconscious.com and use code SKINNY at checkout for 15% off your first purchase. This episode is sponsored by Momentous Go to livemomentous.com/skinny and try it today at 20% off with code SKINNY, and start living on purpose. This episode is sponsored by SAKS  Shop SAKS.com. This episode is sponsored by Addyi  Learn more at Addyi.com. Produced by Dear Media  

Intelektualni podkast. Fudbal (onako) - Čukarički, CSKA, TSC. Košarka (dizaster) - Pumpai, Efes, Mornar, Alba, Bajern. Koja je uloga hrčka? Studio Hrizantema: Trobi, Vili, crk Trajanje: 95 minuta ---------------------------------- Pokrenuli smo PATREON, pa ko želi sada može da časti za neko pivo, dodatne sadržaje i/ili tehničke popravke na podcastu: www.patreon.com/pfchisterical A ima i opcija za direktne donacije: paypal.me/partizanhisterical ---------------------------------- HISTI RADIO MIX br. 87 https://www.youtube.com/watch?v=dnIk0TLCZtk&list=PLwhKCZrlUHqjLHtwXHKYEBQ2rdf8BKxb6 Twitter: www.twitter.com/pfchisterical Instagram: www.instagram.com/pfchisterical/ Youtube: www.youtube.com/c/PartizanHistericalPodcast podcast.rs/show/histerical/ NAPRED PARTIZAN! NAPOMENA: Ovo je "uradi sam" podkast u kome navijači Partizana razgovaraju o zbivanjima u svom voljenom klubu. Izneta mišljenja i stavovi su lični, kafanski, i ne predstavljaju stavove bilo koje navijačke grupe, frakcije, dela uprave, radne ili druge organizacije. Nismo insajderi, eksperti, sportski radnici. Apsolutna vernost, ne apsolutna istina. Trudimo se da jezik koji koristimo bude fin književni - možete ga čuti na svakom stadionu i u svakoj sportskoj hali. Cover foto: FK Partizan Majstor zvuka: crk Realizacija: Slavko Tatić, gajtan, štap, kanap, Kiša metaka & Histi

#823: Join us as we sit down with Laura Modi – Co-Founder & CEO of Bobbie, the mom-founded & led infant feeding company that has become the third-largest fully integrated infant formula manufacturer in the US! Designed to mirror breast milk, Bobbie is an organic baby formula crafted with intentional ingredients & simple recipes to support healthy infant growth – all while working to break the stigma surrounding formula feeding. In this episode, Laura unpacks the truth about high-quality infant formula, breaks down the difference between US & EU standards, advocates for greater acceptance for diverse feeding choices, & gets real about the societal pressures parents face when navigating formula feeding.   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Bobbie click HERE   To connect with Laura Modi click HERE    To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   To purchase Bobbie, use code SKINNY at hibobbie.com/skinny for 20% off the first three months of a Bobbie infant formula subscription.   This episode is sponsored by The Skinny Confidential   Optimize your daily beauty routine. Shop The Skinny Confidential Mouth Tape at shoptheskinnyconfidential.com.   This episode is sponsored by FORA Travel   Visit foratravel.com/skinny and let them know you came from SKINNY to learn what it means to travel, upgraded. This episode is sponsored by LMNT   Get yours at DrinkLMNT.com/SKINNY.   This episode is sponsored by Noom   Start your GLP-1 journey today at Noom.com.   This episode is sponsored by Cymbiotika    Go to Cymbiotika.com/TSC for 20% off + free shipping.  Produced by Dear Media

#821: Join us as we sit down with Bethenny Frankel – self-made businessperson, TV producer, podcast host, multiple New York Times bestselling author, philanthropist, social media powerhouse, & most importantly, a mother.  As a trailblazer for female founders, Bethnenny has redefined success as a self-made business mogul who has disrupted industries from reality television, to the beverage & lifestyle space with her Skinygirl empire, to venture capital & so much more! In this episode, Bethenny shares her journey of building a brand from the ground up, her sharp business instincts, & the lessons she learned along the way. She opens about the highs & lows of entrepreneurship, the importance of authenticity in business, & how she continues to evolve in an ever-changing landscape. Tune in for a candid, no-BS conversation with one of the most dynamic & outspoken women in business today!    To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Bethenny Frankel click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   Join Bethenny's BStrong Mission at Bethenny.com/BStrong – providing emergency assistance to people in crisis, an initiative in partnership with the global empowerment mission.    Visit Bethenny.com to learn more about Bethenny, shop The List, & tune into her podcast, Just B with Bethenny.    This episode is sponsored by The Skinny Confidential   Optimize your daily beauty routine. Shop The Skinny Confidential Mouth Tape at shoptheskinnyconfidential.com.   This episode is sponsored by Cymbiotika   Go to Cymbiotika.com/TSC for 20% off + free shipping.   This episode is sponsored by Fatty15   You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/SKINNY and using code SKINNY at checkout.   This episode is sponsored by Jolie    Head to jolieskinco.com/SKINNY to try it out for yourself with FREE shipping.   This episode is sponsored by Branch Basics   Visit branchbasics.com/SKINNY15 and use code SKINNY15 at checkout for 15% off + free shipping your first order of your Premium Starter Kit today.    This episode is sponsored by Ritual   Start a Ritual that's backed by science, without the B.S. Ritual is offering 25% off your first month at ritual.com/SKINNY.   Produced by Dear Media

#820: Join us as we sit down with Dr. Morgan Cutlip – relationship expert & author, who shares actionable strategies for navigating mental load, marriage, & motherhood. From identifying burnout in relationships to prioritizing self-care & overcoming guilt tied to household responsibilities, Dr. Morgan offers a roadmap for balancing it all. In this episode, Dr. Morgan dives into modern gender dynamics, shifting relationship roles, the power of appreciation, & the nuances of effective communication.   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Dr. Morgan Cutlip click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   To learn more about Dr. Morgan Cutlip and purchase her latest book, A Better Share, click HERE.   This episode is sponsored by The Skinny Confidential   Optimize your daily beauty routine. Shop The Skinny Confidential Mouth Tape at shoptheskinnyconfidential.com.   This episode is sponsored by Smart Mouth   Find SmartMouth at Walgreens, Walmart, Amazon or visit smartmouth.com/skinny to snag a special discount on your next SmartMouth purchase.   This episode is sponsored by NOBULL   Visit nobullproject.com/tsc for 30% off your entire order.    This episode is sponsored by Primal Kitchen   Head to primalkitchen.com/skinny to save 20% off your next online order with code SKINNY at checkout.   This episode is sponsored by Cymbiotika   Go to Cymbiotika.com/TSC for 20% off + free shipping.   This episode is sponsored by Skims   Check out SKIMS best intimates including the Fits Everybody Collection and more at skims.com/skinny #skimspartner   Produced by Dear Media

猫のシッポPodcast第604回【猫のシッポPodcast】第604回 グミの話（後半） #猫のシッポ公式Twitterは @catstailpodcast公式ハッシュタグは #猫のシッポ公式メールアドレスは catstailpodcast@gmail.com 公式Webサイトは catstailpodcast.seesaa.net です。1.オープニング　・寒いです。2.猫博士のコーナー　　お休み3.本編　・グミの話（後半）4.成果発表コーナー　・お休み5.TSCのコーナ..

#817: Join us as we sit down with Sara Brooks – co-founder of Goldilocks, a brand consultancy specializing in consumer packaged goods. Throughout her career, Sara has worked with nearly 200+ CPG brands – ranging from pre-revenue startups to post-IPO giants – dedicating her expertise to founder-led business looking to disrupt the status quo. Previously, she founded & led Covet PR, a powerhouse agency that quickly rose to become an industry leader before being acquired by leading performance marketing firm, Power Digital. In this episode, Sara shares valuable insights on effective brand positioning, the power of creative branding & consistency, meaningful consumer connections, leveraging marketing insights for innovation, & must-know tips for aspiring entrepreneurs. If you are looking to elevate your brand, this one's for you!   To Watch the Show click HERE   To Watch the Show with Kira click HERE    For Detailed Show Notes visit TSCPODCAST.COM   To connect with Sara Brooks click HERE   To connect with Goldilocks click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   To learn more about Goldilocks and start working with them visit itsgoldilocks.com.   This episode is sponsored by YNAB   TSC Him & Her Show listeners can claim an exclusive three-month free trial, with no credit card required at YNAB.com/skinny.   This episode is sponsored by ARMRA   Go to tryarmra.com/SKINNY or enter SKINNY to get 15% off your first order.    This episode is sponsored by Caraway   Visit Carawayhome.com/theskinny10 or use code THESKINNY10 at checkout to take an additional 10% off your next purchase.   This episode is sponsored by LMNT    Get yours at DrinkLMNT.com/SKINNY.   This episode is sponsored by Squarespace   Go to squarespace.com for a free trial, and when you're ready to launch, squarespace.com/SKINNY to save 10% off your first purchase of a website or domain.    This episode is sponsored by Cymbiotika   Go to Cymbiotika.com/TSC for 20% off + free shipping. Produced by Dear Media

Nancy is a Co-Founder and Managing Partner atRallyday Partners, a private equity firm built byfounders for founders, focused on lower middlemarket growth companies.Nancy's experience as an entrepreneur informs her role as an investor at Rallyday Partners. Nancy and thefounding team at Rallyday wanted to build the private equity firm that they would have wanted to partnerwith on their own entrepreneurial journeys. In practice, this involves a multi-stakeholder approach and anintense focus on purpose, culture, leadership development alongside the typical focus on growth and financialreturns. Rallyday's purpose statement is to Empower leaders to go even bigger, create the most value for themost people, and share in the experience of a lifetime. As Managing Partner, Nancy leads efforts to identifynew investment opportunities and guides value creation efforts in partnership with portfolio companyleadership teams. Nancy leads Rallyday's investments in Highbar Health, Livefront, Nimble Gravity, andKicksaw and supported Pyx Health to a successful exit in 2023.Nancy is a 35 year + veteran of the telecommunications and IT infrastructure industry. She has spent herentire career building and growing service-focused organizations demonstrating the power of people in atechnical world. A longtime leader in Denver's tech industry, she co-founded ViaWest in 1999 and served as itsPresident & CEO, successfully scaling the company to become one of the largest colocation and cloudproviders in the industry. In 2017, the company was acquired by GI Partners for $1.675 billion and combinedwith Peak10, another IT infrastructure powerhouse. Now called Flexential, the company is a leading providerof data center solutions spanning colocation, connectivity, cloud, managed solutions and security services.Nancy served as chair of the board until the end of 2024.Previously, Nancy served as president of Shaw Business Infrastructure Services, a division of ShawCommunications (NYSE:SJR). Nancy held founder and executive leadership positions with numeroustechnology companies, including TSC, ConferTech International, ITC, RMI.net and Intrepid Communications,where she enabled significant growth while maintaining a deep customer-centric focus. She has raised over$1.1B in equity during her career and consistently provided strong returns to her shareholders.Nancy is a passionate supporter of the Colorado entrepreneurial community as well as furthering theparticipation and advancement of women in computer science. She serves on the boards of the NationalCenter for Women and Information Technology, where she is chair; Blackstone Entrepreneurs Network; EspireDental; Highbar Health; Livefront; Nimble Gravity; and Kicksaw and formerly served on the NationalCybersecurity Center as well as the University of Denver Board of Trustees.Nancy has received numerous accolades for her visionary leadership and, in 2016, was honored with theinaugural Colorado Governor's Citizenship medal for Growth and Innovation, which recognized her as anentrepreneur with exceptional ingenuity who seeks to inspire and create new possibilities for others. She alsowas selected as the 2016 EY Entrepreneur of the Year in Technology Services for the Mountain Desert Region.Nancy has also been recognized in the global technology community when she received the CanadianGovernor General's Medallion in recognition of her distinguished track record building technology businesses.Nancy embraces the best of Colorado by spending time with family including her beloved black lab, Brooklyn,in the mountains skiing, cycling and hiking. A native of Toronto, Nancy received a Bachelor of Arts degree fromQueens University in Canada. Michelle Collie is a Physical Therapist and business owner who grew her company from one location to 35 and has now partnered with RallyDay to continue growth in the the Northeast United States.  She has been a Board Member of the American Physical Therapy Private Practice Association and has received numerous awards as a Best Employer!  Her company is now Highball Health.

#814: Join us as we sit down with Loren Ridinger – influential businesswoman, entrepreneur, motivational speaker, best-selling author, and Co-Founder & CEO of Market America Worldwide | SHOP.com, a global e-commerce & product brokerage company. With over 30 years of experience, Loren has empowered millions, building a thriving empire alongside her late husband, JR Ridinger. In this episode, Loren opens up & gets vulnerable, reflecting on JR's legacy, the values that shaped their success, & how she found strength to move forward after his sudden passing. Loren shares insights from her latest book, Scrambled or Sunny-Side up? Living Your Best Life After Losing your Greatest Love, offering wisdom on navigating grief, embracing each day, & choosing to live fully – no matter what life serves up next.    To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Loren Ridinger click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Get your burning questions featured on the show! Leave the Him & Her Show a voicemail at +1 (512) 537-7194.   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   To purchase Loren Ridinger latest book, Scrambled or Sunny-Side Up? Living Your Best Life After Losing Your Greatest Love visit scrambledorsunnysideup.com.   This episode is sponsored by ARMRA     Go to tryarmra.com/SKINNY or enter SKINNY to get 15% off your first order.   This episode is sponsored by YNAB   TSC Him & Her Show listeners can claim an exclusive three-month free trial, with no credit card required at YNAB.com/skinny.   This episode is sponsored by Netflix - Running Point   Running Point, now streaming only on Netflix.   This episode is sponsored by Cymbiotika    Go to Cymbiotika.com/TSC for 20% off + free shipping.   This episode is sponsored by Dr. Diamonds Metacine   Visit DrDiamondsMetacine.com to learn more about the InstaFacial(R) Collection and use code SKINNY at checkout for a free sample of award-winning InstaFacial(R) Plasma with any purchase of $200 or more.   This episode is sponsored by Live Conscious Collagen Peptides   Visit weliveconscious.com and use code SKINNY at checkout for 15% off your first purchase.   Produced by Dear Media

Website: http://www.tsc.nyc*Uploaded with permission from TSC.Carter Conlon is at the Worldwide Prayer service at Yale University. Enjoy this service, message, and time of worship and prayer. If you've just made a decision to be born again, please respond here: https://bit.ly/ConnectwithTSCWe'd be honored to help you on your next steps! If you would like to contribute financially and help us create more opportunities for people to experience a life-changing relationship with Jesus, click here: https://tsc.nyc/give/#carterconlon #yaleuniversity #worldwideprayer Chapters: 00:00:00 - 00:06:10 - Intro00:06:11 - 00:50:49 - Worship00:50:50 - 01:32:40 - Carter Conlon01:32:41 - 0:2:04:08 - Worship

Welcome to an intense Naruto discussion in this episode! We kick things off by revisiting an old debate—who would win in a fight between Orochimaru and Killer Bee? It's a matchup that's been on our minds, and now we're picking up the pieces to hash it out once and for all! Then, we dive deep into the Hokage Rankings! From the legendary First Hokage all the way to the Seventh Hokage, we break down each leader's strengths, weaknesses, and legacy to debate who reigns supreme as the best Hokage of all time!

#811: Join us as we sit down with Donald Miller – CEO of StoryBrand, a company revolutionizing how businesses clarify brand messaging through the power of storytelling. Best known for his StoryBrand framework, Donald reveals the secrets behind impactful marketing & branding strategies. In this episode, Donald dives into the power of problem-solving in branding, the formula for compelling storytelling, & the profound impact of clear messaging. Plus, Donald reveals the evolution of StoryBrand & how he has integrated AI with StoryBrand.ai, a tool designed to streamline brand messaging like never before! To Watch the Show click HERE For Detailed Show Notes visit TSCPODCAST.COM To connect with Donald Miller click HERE To connect with Lauryn Bosstick click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697) This episode is brought to you by The Skinny Confidential Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes. Visit donaldmiller.com to learn more about Donald Miller. Click HERE to purchase his best-selling books, including his latest addition, Building A StoryBrand 2.0. For a free trial of StoryBrand.ai click HERE. This episode is sponsored by Chomps Get 15% off your order of Chomps meat sticks at Chomps.com/SKINNY with code SKINNY. This episode is sponsored by Cymbiotika  Go to Cymbiotika.com/TSC for 20% off + free shipping. That's Cymbiotika.com/TSC to claim 20% off + free shipping today. This episode is sponsored by Skims Shop SKIMS best intimates including the Fits Everybody Collection and more at SKIMS.com/skinny and SKIMS stores. This episode is sponsored by Agent Nateur Visit AgentNateur.com and use code SKINNY for 20% off sitewide. This episode is sponsored by Live Conscious Collagen Peptides Visit weliveconscious.com and use code SKINNY at checkout for 15% off your first purchase. This episode is sponsored by Fatty15 Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/SKINNY and using code SKINNY at checkout. Produced by Dear Media  

Steve interviews Jeff Passan (00:20:16) ESPN's Senior MLB Insider. Passan, most famous for being TSC's first guest, returns to talk about the upcoming baseball season. Of course, most of the conversation isn't about baseball. Steve and Jeff talk about the weather, being a man around the house, and Francesco Camarda. Eventually, the baseball discussion begins. Jeff spends most of the talk disagreeing with Steve's opinions about the economics of baseball, Ohtani the heel, and MVP voting. Jeff also gives us some teams he is high on for 2025 and some teams he is down on. Plus, the Pittsburgh Pirates, what the fuck? Steve starts the show with First Things First and talks about the undisputed success of the 4 Nations tournament, a dark day for Italian soccer, and Juan Soto giving a teammate a giftI The show ends with one last thing about being around reaching out to your friends. For more information follow the podcast on twitter @sports_casters Email: thesportscasters@gmail.com

#809: Join Lauryn Bosstick as she sits down to discuss your burning questions about her recently announced pregnancy! As Michael & Lauryn prepare to welcome another child, Lauryn gets real about how she is best preparing for birth. In this episode, Lauryn shares her intentional approach to postpartum preparation, discusses her first trimester cravings, shares her fitness regimen & self-care practices, & emphasizes the power of positive affirmations!   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697)   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE and LTK page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   This episode is sponsored by ARMRA   Go to tryarmra.com/SKINNY or enter SKINNY to get 15% off your first order.   This episode is sponsored by Just Thrive    Visit JustThriveHealth.com and use code SKINNY90 for 20% off your first 90 day bottle.   This episode is sponsored by Chomps   Get 15% off your order of Chomps meat sticks at Chomps.com/SKINNY with code SKINNY.   This episode is sponsored by Jolie   Jolie will give you your best skin & hair guaranteed. Head to jolieskinco.com/SKINNY to try it out for yourself with FREE shipping.   This episode is sponsored by Agent Nateur   Head to AgentNateur.com and use code SKINNY for 20% off sitewide.   This episode is sponsored by Cymbiotika    Go to Cymbiotika.com/TSC for 20% off + free shipping.   Produced by Dear Media

Hoy con La marsellesa de los borrachos, documental musical de Pablo Gil Rituerto, que se estrena el próximo viernes. Y con TSC. Diario da noite, libro del periodista y escritor Alfonso Armada.Escuchar audio

We're launching Season 5 with an EPIC sports segment you don't want to miss! This isn't just any episode—the whole squad is here: our three hosts, plus the dynamic force of our moderators and engagement team—TSC SKII, TSC KOV, and TSC AQUA—ready to break it all down.

Sign up for the Jumpstart Your Health Workshop TODAY! Register here: https://www.shaeladaugherty.com/jumpstartyourhealth25 Get Kate's Mom Tummy Rehab - click HERE use code TSC to get 50% off! How to Strengthen Your Core and Heal Diastasis Recti at Any Age Have you ever felt frustrated with your core after having kids? Maybe you've noticed a lingering belly pooch, lower back pain, or even issues like pelvic floor weakness—but no matter how many crunches you do, nothing seems to change. You're not alone, and today, we're breaking down WHY. In this episode of the Simple Fitness Habits Podcast, I'm joined by Kate Horney, pre/postnatal fitness expert and founder of Beyond Fit Mom. She's here to help us understand diastasis recti—what it is, why it matters (no matter how long it's been since you had kids), and how to heal and strengthen your core the right way. What You'll Learn in This Episode: ✔️ What is diastasis recti? Why nearly 60% of moms experience it but don't realize it.✔️ Why core weakness isn't just about “getting your body back”—it affects posture, back pain, pelvic floor issues, and even digestion.✔️ How to know if you have diastasis recti (hint: it's NOT just about looking “pregnant” years later).✔️ The 3-step process to heal your core at ANY stage of life—Reconnect, Retrain, Rebuild.✔️ The biggest mistakes women make with core workouts that can actually make diastasis recti WORSE.✔️ Why traditional ab exercises (like crunches and planks) aren't always the best choice for core healing.✔️ How your core health affects perimenopause, menopause, and long-term strength.✔️ Simple movements you can start today to build a stronger, healthier core. Why This Matters for Every Mom Even if your kids are grown, healing your core is still possible! Strengthening your deep core muscles isn't just about appearance—it's about long-term strength, stability, and feeling GOOD in your body. Whether you're a new mom or decades postpartum, it's never too late to reconnect, retrain, and rebuild your core. Resources & Next Steps:

Join the Jumpstart Your Health Workshop HERE! Get her Mom Tummy Rehab - click HERE use code TSC to get 50% off! Hey, Fit Fam! Today, I'm beyond excited to introduce you to my new friend, Kate Horney, from Beyond Fit Mom! If you're a busy mom navigating the ever-changing seasons of life—whether that's postpartum recovery, perimenopause, or just trying to make fitness fit into your already full plate—this episode is for you. Kate is a pre- and postnatal fitness specialist with nearly two decades of experience in the fitness industry. She's the creator of Beyond Fit Mom, an OB-endorsed fitness program designed to help women strengthen their core, rebuild their bodies after pregnancy, and develop sustainable health habits for life. But what I love most about Kate? She blends faith and fitness in a way that's practical, sustainable, and deeply rooted in stewardship over striving. In This Episode, We Talk About: ✅ Kate's personal journey into fitness and how motherhood reshaped her approach to health✅ How to balance health and fitness without obsessing or feeling guilty✅ Why faith should be at the center of your health journey✅ How Kate creates a culture of wellness in her family (and how you can do the same!)✅ Common struggles moms face—like diastasis recti and postpartum core recovery✅ The difference between training for aesthetics vs. training for longevity and function✅ Simple, sustainable ways to prioritize movement when life is busy Faith & Fitness: Why Your Health is a Form of Worship One of my favorite takeaways from this episode is the reminder that taking care of your body isn't about vanity—it's about honoring the Lord. Kate shares how 1 Corinthians 6:19-20 has shaped her view of fitness and how she teaches women to see movement as an act of worship. When we shift our focus from aesthetics to stewardship, we stop feeling guilty for taking care of ourselves and start seeing our health as a way to better serve God, our families, and our calling. Struggling to Balance Fitness & Motherhood? You're Not Alone. If you've ever felt like you're stuck in the yo-yo cycle of fitness—swinging between obsession and apathy—you're not alone. Kate and I talk about how we've both walked through that struggle, and what it takes to find a sustainable, grace-filled approach to health that works in every season of life. Kate shares how she built Beyond Fit Mom out of a deep desire to help women find freedom—not frustration—in their fitness journey. From postpartum recovery to perimenopause, she's helped thousands of women develop fitness rhythms that are effective, faith-filled, and sustainable. Practical Takeaways from This Episode:

Stuart Hameroff MD is Professor of Anesthesiology and Psychology, and Director of the Center for Consciousness Studies at the University of Arizona in Tucson. Hameroff became interested in intelligent behavior of microtubules, protein lattices which organize activities within living cells. Hameroff and colleagues developed theories of microtubules as self-organizing molecular computers. In the 1990s Hameroff teamed with Sir Roger Penrose on the controversial Penrose-Hameroff "Orch OR" model of consciousness based on quantum computing in brain neuronal microtubules, a notion bolstered by recent evidence. Hameroff also organizes the biennial interdisciplinary conferences, The Science of Consciousness Conference. The Science of Consciousness (‘TSC') conference is the world's longest running inter-disciplinary gathering on the study of consciousness, the nature of existence, and our place in the universe. In 2025 TSC will be in Barcelona, Spain, July 6-11 (Workshops, Plenaries, Concurrents, Exhibits, Demos, Social, Poetry Slam, Dancing - AC Marriott Forum Hotel), preceding and in conjunction with The Festival of Consciousness, July 11-13 (Music, Art, Experiential, Inspiration, Spirituality, Education, Business, Evolution). Speakers include: Sir Roger Penrose, Donald Hoffman, Robert Lawrence Kuhn, Rupert Sheldrake, Deepak Chopra, Federico Faggin, Anirban Bandyopadhyay, and many others. Links below for TSC tickets & more information. TIMESTAMPS: (0:00) - Introduction (1:04) - Defining Consciousness (4:15) - Microtubules & Anaesthesia (9:00) - Where it began with Sir Roger Penrose (15:13) - Patricia Churchland's hilarious critique on Hameroff & Penrose (25:45) - Objective Reduction Explained (37:27) - Quantum Biology (40:47) - Philosophical Implications (Hard Problem, NDEs, OBEs, Afterlife & Reincarnation) (46:00) - Time Crystals & Life (54:20) - Spectrum of Consciousness (plants to humans) (57:37) - "Cartoon Neurons" (1:00:31) - IIT vs GNWT vs Predictive Processing vs Higher-Order Thought vs Orch OR (Battle of Consciousness Theories!) (1:07:23) - Ethical/Practical Implications (Healthcare) (1:10:40) - Transcranial Ultrasound Explored (1:18:10) - How Does Anaesthesia Affect Consciousness? (1:22:10) - The Science of Consciousness Conference & Festival of Consciousness (1:28:00) - Astrobiology & Conformal Cyclic Cosmology (1:30:20) - The Microtubule Maestro's future (1:36:32) - Conclusion EPISODE LINKS: - Stuart's Website: https://hameroff.arizona.edu/ - Stuart's X: https://twitter.com/stuarthameroff - TSC: https://consciousness.arizona.edu/ - TSC 2025 Flyer: https://tinyurl.com/4y94zwhr - TSC Youtube: https://www.youtube.com/@thescienceofconsciousness - Patricia Churchland: https://youtu.be/6IVBxmaaGNg?feature=shared - Christof Koch: https://youtu.be/GeO5zr1e5lc?feature=shared - Susan Blackmore: https://youtu.be/u1VlYfgCHTA?feature=shared - Donald Hoffman: https://youtu.be/QRa8r5xOaAA?feature=shared - Federico Faggin: https://youtu.be/MSn4t6fP_dc?feature=shared CONNECT: - Website: https://tevinnaidu.com - Podcast: https://creators.spotify.com/pod/show/mindbodysolution - YouTube: https://youtube.com/mindbodysolution - X: https://twitter.com/drtevinnaidu - Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu - LinkedIn: https://linkedin.com/in/drtevinnaidu ============================= Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.

Welcome to Courage to Advance, hosted by Kim Bohr and brought to you by SparkEffect, in partnership with The Empathy Edge. Tune in here every 3rd Thursday, or visit CourageToAdvancePodcast.com.Kim Bohr and anthropologist Aaron Delgaty, PhD dive deep into the "arrival fallacy" - the pervasive belief that happiness and fulfillment lie just beyond the next project deadline, quarter, or milestone. Drawing from extensive research on workplace dynamics, they explore how four essential elements - continuity, reciprocity, purpose, and hope - shape our working relationships and overall job satisfaction. Through the lens of anthropology and organizational behavior, they examine why we fall into patterns of perpetually postponing contentment and how this impacts everything from team dynamics to bottom-line business outcomes.The conversation weaves together insights from Gallup's research on employee engagement, real-world examples of boundary setting, and practical strategies for breaking free from the "things will get better" cycle. You will be challenged to have honest conversations about work relationships and learn why misalignment isn't always about bad management. To access the episode transcript, please search for the episode title at www.TheEmpathyEdge.comKey Takeaways:Having honest conversations with yourself and others is crucial for maintaining healthy working relationshipsThe four essential elements of working relationships are: continuity, reciprocity, purpose, and hopeSetting clear boundaries is vital for sustainable work practices and personal wellbeingMisalignment in work relationships isn't always about bad management - sometimes it's about fitEven introverts need to talk about workplace challenges to create positive change"The arrival fallacy is like balancing on a one-legged stool of hope. You might maintain it temporarily, but you're operating on an unsustainable promise of 'someday.'" - Aaron Delgaty, PhDAbout Aaron Delgaty, PhDAaron Delgaty, PhD, is a cultural anthropologist and ethnographer. He received his doctorate in cultural anthropology from the Univeristy of North Carolina at Chapel Hill in 2020. His research explores what shapes worker and workplace resilience and how resilience resists, crumbles, or reforms in the aftermath of personal and collective disaster. In addition to teaching research methods and anthropological theory, Aaron leads research for brand strategy agency TSC.About SparkEffectSparkEffect partners with organizations to unlock the full potential of their greatest asset: their people. Through their tailored assessments and expert coaching at every level, SparkEffect helps organizations manage change, sustain growth, and chart a path to a brighter future.Go to sparkeffect.com/edge now and download your complimentary Professional and Organizational Alignment Review today.Connect with Aaron Delgaty, PhDThe anthropology of work: aarondelgaty.comTSC: tsc.chatAaron's Book: Working Relationships: Crisis and resilience at the heart of employee experienceLinkedIn: linkedin.com/in/adelgatyConnect with Kim Bohr and SparkEffectSparkEffect: sparkeffect.comCourage to Advance recording and resources:sparkeffect.com/courage-to-advance-podcastLinkedIn: linkedin.com/company/sparkeffectLinkedIn for Kim Bohr: linkedin.com/in/kimbohr Connect with Maria:Get Maria's new book: TheEmpathyDilemma.comLearn more about Maria and her work: Red-Slice.comHire Maria to speak at your next event: Red-Slice.com/Speaker-Maria-RossTake my LinkedIn Learning Course! Leading with EmpathyLinkedIn: Maria RossInstagram: @redslicemariaFacebook: Red SliceThreads: @redslicemariaAchieve radical success putting empathy into action with Businessolver. Techlology with heart, powered by people. https://www.businessolver.com/edge

What, you may ask, is TSC. When I first met our guest, Kari Luther Rosbeck, I had the same question. TSC stands for tuberous sclerosis complex. As soon as Kari defined the term for me it struck a nerve close to home for me. My great nephew actually has tuberous sclerosis complex and was first diagnosed with this rare disease when he was but a child. My conversation with Kari was far reaching and quite educational for me as I suspect it will be for you.   TSC affects some fifty-thousands persons in this country and about 1 million around the world. The TSC alliance, founded in 1974, has worked to promote support, research and the dissemination of information about this rare disease.   Kari has been the CEO for many years. She began with the organization in 2001. While her main interest growing up was in being an actress as she says, “living in New York City means that you work while developing an acting career”. In Kari's case, she found another interest which was fundraising and being involved in the nonprofit world.   My conversation with Kari is quite enjoyable and, as I said, quite educational. I am sure you will find much invaluable information in this episode. At the end of our time together Kari will tell us all how we can become involved and help the TCS Alliance. I hope you will find ways to support this effort as what the organization does goes far beyond what you might think.       About the Guest:   Kari Luther Rosbeck, President and CEO, TSC Alliance Kari has made it her life mission to use her 35 years of nonprofit and volunteer management experience to help create a future where everyone with TSC has what they need to live their fullest lives.  She has served as President and CEO since November 2007 and previously held progressive leadership positions with the organization since 2001. Kari is responsible for the overall management and administration of the organization including strategic planning, implementation of organizational strategies and evaluation of results to ensure the TSC Alliance meets its mission. During her tenure, the TSC Alliance established a comprehensive research platform fostering collaboration with industry and academia to move treatments for TSC forward in a more expedited way. Because of her leadership, the organization has taken an active role in educating the TSC community about clinical trials to diminish the time for recruitment, including pivotal trials that have led to three FDA-approved drugs specifically for TSC. In 2019, the organization launched a Research Business Plan with the goal to change the course of TSC for those living with it today and for generations to come paired with an aggressive fundraising campaign leading to more than $16 million raised. Since joining the TSC Alliance, the organization has grown from a $2.1 million annual operating budget to $10 million in 2022 and is heralded with top ratings by watchdog organizations. Kari graduated with a BA degree in Theatre from the State University of New York at Albany and upon graduation founded a theatre company with fellow graduates in New York, NY.  After the loss of her first child, Noell, to sudden infant death, she dedicated her career to helping other families. Kari is the proud mother of Trent, Bradey, Wynter and Rhys and grateful to her husband Chris for his unending support. When not working, she enjoys traveling, playing golf and being an avid Minnesota Vikings fan. Read Kari's Profile in Success.   Ways to connect with Kari:   Facebook: https://www.facebook.com/tscalliance; @krosbeck Instagram: https://www.instagram.com/tscalliance; @karirosbeck LinkedIn: https://www.linkedin.com/company/697362/admin/; @kari-luther-rosbeck-ba24805/ X: https://twitter.com/tscalliance; @KariRosbeck Threads: https://www.threads.net/@tscalliance Website: www.tscalliance.org     About the Host:   Michael Hingson is a New York Times best-selling author, international lecturer, and Chief Vision Officer for accessiBe. Michael, blind since birth, survived the 9/11 attacks with the help of his guide dog Roselle. This story is the subject of his best-selling book, Thunder Dog.   Michael gives over 100 presentations around the world each year speaking to influential groups such as Exxon Mobile, AT&T, Federal Express, Scripps College, Rutgers University, Children's Hospital, and the American Red Cross just to name a few. He is Ambassador for the National Braille Literacy Campaign for the National Federation of the Blind and also serves as Ambassador for the American Humane Association's 2012 Hero Dog Awards.   https://michaelhingson.com https://www.facebook.com/michael.hingson.author.speaker/ https://twitter.com/mhingson https://www.youtube.com/user/mhingson https://www.linkedin.com/in/michaelhingson/   accessiBe Links https://accessibe.com/ https://www.youtube.com/c/accessiBe https://www.linkedin.com/company/accessibe/mycompany/   https://www.facebook.com/accessibe/       Thanks for listening!   Thanks so much for listening to our podcast! If you enjoyed this episode and think that others could benefit from listening, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a comment in the section below!   Subscribe to the podcast   If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts or Stitcher. You can subscribe in your favorite podcast app. You can also support our podcast through our tip jar https://tips.pinecast.com/jar/unstoppable-mindset .   Leave us an Apple Podcasts review   Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. If you have a minute, please leave an honest review on Apple Podcasts.       Transcription Notes:   Michael Hingson ** 00:00 Access Cast and accessiBe Initiative presents Unstoppable Mindset. The podcast where inclusion, diversity and the unexpected meet. Hi, I'm Michael Hingson, Chief Vision Officer for accessiBe and the author of the number one New York Times bestselling book, Thunder dog, the story of a blind man, his guide dog and the triumph of trust. Thanks for joining me on my podcast as we explore our own blinding fears of inclusion unacceptance and our resistance to change. We will discover the idea that no matter the situation, or the people we encounter, our own fears, and prejudices often are our strongest barriers to moving forward. The unstoppable mindset podcast is sponsored by accessiBe, that's a c c e s s i capital B e. Visit www.accessibe.com to learn how you can make your website accessible for persons with disabilities. And to help make the internet fully inclusive by the year 2025. Glad you dropped by we're happy to meet you and to have you here with us. . Well, welcome once again to another episode of unstoppable mindset where inclusion, diversity and the unexpected meet, and I bet we get to do a bunch of all of that today. Our guest is Kari Luther rosbeck, and Kari and I met through Sheldon Lewis from accessibe. Sheldon is great at finding folks for us to get to chat with. And when I started learning about Kari, one of the things that I kept reading was a term TSC, and I didn't know what TSC was. So when Kari and I first met, I asked her about TSC, and she said it stands for tubular sclerosis complex, which immediately struck a nerve with me, because I have a great nephew who has tubular sclerosis. And as it turns out, his parents have actually and had actually attended an event where Kari was and then just this past March or April or whenever, and you can correct me, Kari, but they went to another event, and my other niece and nephew, Tracy and Charlie, attended, as I just told, Kari, I'm very jealous they didn't let me come along, but that's okay. I stayed home and slept. But anyway, Kari, I want to welcome you to unstoppable mindset. It's really great that you're here, and I want to thank you for taking the time to be with us. It   Kari Luther Rosbeck ** 02:42 is such an honor. Michael and I love talking with your family, and it was so wonderful to have them with us at comedy for a cure this year. Well, it   Michael Hingson ** 02:53 it was really fun to hear about the event from them, and I'm glad that that they all enjoyed it. And of course, Nick is is a person who deserves all the attention and help all of us can give. He's had tubular sclerosis, been diagnosed with it for quite a while, and is actually, I think, beating some odds, because some people said, Oh, he's not going to last very long, and he's continuing to do well. And just don't ever get him into a conversation about sports and the Dodgers, because he's a Dodger fan, okay,   03:24 as he should be. By the conversation.   Michael Hingson ** 03:28 Well, he is a Dodger fan as he should be. I just want to point that out, yes, yes, for those of us here. Well, Nick, Nick probably   Kari Luther Rosbeck ** 03:36 was, well, when Nick was diagnosed, we had a very different prognosis for TSC back then.   Michael Hingson ** 03:45 Well, yeah, I know, and it's like everything with medicine, we're making a lot of advances. We're learning a lot, and of course, we're paying a lot of attention to these different kinds of issues. I mean, even blindness, we're paying a lot of attention to blindness, and we're slowly getting people it's a very slow process, but we're slowly getting people to recognize blindness isn't the problem. It's our attitudes about blindness that are the problems. And I think that's true with most things, and I think that if people really thought about Nick and and felt, well, he can't do much because of they would recognize he can do a whole lot more than they think he can, 100% which is really important. Well, let's start a little bit about you. And why don't you tell us about the early Kari growing up and all that and how we got where we are, well, thank   Kari Luther Rosbeck ** 04:43 you for the opportunity to do that. My middle name is Lacher. That's also my maiden name. My dad and mom were in education, primarily. My dad also dabbled in some politics. We moved around. Quite a bit when I was a child, I think before seventh grade, or before I was 18, we knew 13 times so that really, you know, you become adaptable because you have to be and inclusive, because you have to be because you're in all of these new environments. From the time I was six years old, I wanted to be an actress. I wrote my own plays, I organized a neighborhood, I think, when I was seven, and we performed a play I wrote. And that's what my degree is in, in theater. And Michael, as you probably know, when I was 27 I had my first child, Noel, who unfortunately passed away from sudden infant death, and it completely changed the rest of my life. From that point forward, I really wanted to do something that impacted families, so they never had to experience the type of grief that I went through at a very somewhat young age. And then from from that point, I took all of the skills that I'd been using in the work life, not theater, because I lived in New York, and you have to work to live, so you could do theater before my then husband and I moved to Minneapolis, but I had always done fundraising. I had always done administration, so I just kind of naturally took in all of those skills, community and grassroots building. I went to work for the American Refugee Committee in Minneapolis, and then from there, worked at international service agencies, which is a workplace giving umbrella organization representing all of the premier international organizations. And my job there, as a regional director was to go into workplaces and give two or three minute presentations and convince people to give to international causes. My favorite was I was pregnant. I had a pregnancy kit, what they would give people in developing the developing world, where you would have a razor blade, a string, a plastic sheet, and that's how they delivered babies. And that was a really effective presentation, as you can imagine. I got to the TSC Alliance because my boss at international service agencies became the CEO of the TSC Alliance in early 2000s and he brought me over to start our volunteer outreach program, build our grassroots movement, and from there, I definitely got involved in fundraising. The admin side was interim CEO, and then CEO,   Michael Hingson ** 07:55 well, gee, so so many questions. Why did you guys move so many times?   Kari Luther Rosbeck ** 08:01 Well, my dad got his PhD and became dean of students at Arkadelphia State University, or Henderson State University in Arkadelphia, rather. And he did great, but he loved politics, and he had the opportunity to become the executive director of the Republican Party of Arkansas when it wasn't cool to be a Republican in Arkansas, and that really was his passion. And from there, he became a he led a congressional campaign for a candidate in Littleton, Colorado, and when that candidate didn't win, he realized that he really needed to have a more stable life for his family. So we moved to Knoxville, Illinois, and he became a vice president at a community college, and from that point forward, that was his his career. We moved to upstate New York. I'm leaving out a few moves just to make it simple. We moved to upstate New York my freshman year in college, where he became a President of Community College there, and then ultimately, he ended back in his hometown, in Mattoon, Charleston, Illinois, where he led the local community college until he retired, and the Student Union at Lakeland College is actually named after my   Michael Hingson ** 09:30 father. Wow. So is he still with us today? He is not.   Kari Luther Rosbeck ** 09:34 He passed away from idiopathic pulmonary fibrosis in 2017   Michael Hingson ** 09:38 Well, that's no fun. How about your mom? She is, she   Kari Luther Rosbeck ** 09:43 still lives in that soon. Yep, she is the matriarch of our family. That's for sure.   Michael Hingson ** 09:50 A lot of moves. Needless to say, I wonder what your father would say about politics today, it started to be different in 2016 and. 2017 but I wonder what he would think about politics in general. Today, I   Kari Luther Rosbeck ** 10:04 am not sure. I have wondered that question a lot. The one thing my dad was always great at, though, was the ability to see balanced viewpoints, and it's something I always loved and respected about my father, and   Michael Hingson ** 10:19 I think that's important. I think people really need to do more of that. And we just, we're not, we're not seeing that, which is really scary. We're not seeing it on so many levels, not just politics. But, you know, we don't get into politics much on unstoppable mindset, because, as I love to tell people, if we do that, I'm an equal opportunity abuser anyway, and and I, and I'm with Mark Twain. Congress is that grand old benevolent asylum for the helpless. So you know?   Kari Luther Rosbeck ** 10:48 Well, I will say this. My dad taught me how to be an advocate from a very young age. Yeah, what it means to not be afraid to use your voice. That's the best thing we can get out of politics, that using your voice for the greater good is one of the most important things that you can do. The   Michael Hingson ** 11:10 thing that I think people are forgetting today is they love to use their voice, but they don't love to use their ears. Yes, which is another thing, but I I hear what you're saying. I joined the National Federation of the Blind, which is the largest blindest consumer organization in the country, and I joined in 1972 when I was a senior in college, and learn from experts about being an advocate. And I think it's really important that we have advocacy. And the value of really good advocates is that they are able to look at all sides of an issue and really make intelligent decisions and also recognize when it's time to maybe change as things evolve in terms of views. And we just don't see any of that today. People say I'm an advocate. Yeah, well, without thinking about it, and without really looking at the options, and without looking at stands, it's just amazing how people, as I said, use their voices, but not their ears today. I agree. Yeah, it's, it's, it's a tough world, and it's, it's a challenge. I read an article about a year ago in the New York Times all about how we're losing the art of real conversation, which is why this podcast is so much fun, because we do get to converse.   Kari Luther Rosbeck ** 12:36 That's right, I I'm so excited to be with you today.   Michael Hingson ** 12:40 Well, so you got into nonprofit, in a sense, pretty early, and you've certainly been involved at reasonable levels for now, 23 years after September 11, I worked at Guide Dogs for the Blind for six and a half years, as well as being a public speaker. But loved working in the nonprofit sector, although I had a lot of fun with some of the nonprofit people, because what I would constantly advocate, if you will, is that development in the nonprofit world is really just no different than sales. Instead of selling and making a profit, in a sense, you're selling to secure donations, but it's still sales. And people would say, Oh no, it's totally different, because nonprofit is just totally different than what you do if you're working with a company and selling for a company. And I'm going, I'm not sure it's that different.   Kari Luther Rosbeck ** 13:40 Well, what I think is that you're selling hope and right? It's all about relationships. But unlike widgets, we have a lot of different programs that have created such progress, hope and support for the tuberous sclerosis complex community. And I really enjoy talking about what those programs help make possible for people like your great nephew, Nick well   Michael Hingson ** 14:12 and and it's important to do that. I The only thing I would say on selling widgets, as opposed to hope, is if you talk to Steve Jobs or Bill Gates, they would say that widgets very well could also be a mechanism to to move toward hope and dreams. And so again, I think it's just, it's it's all using the same techniques, but different things. I tell people now that as a keynote speaker, I think it's a whole lot more fun to sell life and hope and dreams than it is to sell computer hardware.   Kari Luther Rosbeck ** 14:54 But you're right about computer hardware, and for instance, wearables that are. Really making a difference in some of the breakthroughs that we see today. So under percent correct.   Michael Hingson ** 15:05 Well, tell us a little bit about the whole tubular sclerosis complex Alliance, the TSC Alliance, and you got started in it. And what was it like, if you will, back in the day, and it's not a great term, I'm telling you, I I'd love to to have fun with that, but what it used to be like, and what it is now, and what's happening, sure.   Kari Luther Rosbeck ** 15:27 So when I started June 18, 2001 nearly 23 years ago, the organization had about seven employees. Today, we have 23 we in those days, we knew what the genes were in TSC, and soon after I came to work, we discovered how the TSC genes impact the underlying genetic pathway. That was awesome, because that led to some key clinical trials and ultimately an approved drug. What I say about the early days is we were we did a beautiful job of holding people's hands, offering them support, but there were no medications that really directly impacted TSC that were FDA approved,   Michael Hingson ** 16:21 maybe it would help if we actually define what TSC is. Yes, of   Kari Luther Rosbeck ** 16:25 course, let's start with that. Tuberous sclerosis complex is a rare genetic disorder that causes tumors to grow throughout the body, the brain, heart, kidney, liver, lungs. It is the leading genetic cause of epilepsy and one of the leading causes of autism. Epilepsy impacts about 85% of people with TSC autism, about 50% one in 6000 life first will have TSC. TSC impacts about 50,000 Americans and a million people worldwide, and it's variable. No two people are exactly the same, not even identical twins. So people can have mild cognitive impact. They might have moderate or severe. People can have mild cognitive impact, but at some point in their life, perhaps needing a lung transplant. TSC is progressive. So for women of childbearing age, lymph angiolio, myomatosis, or Lam can impact the lungs. We can see kidney growth of tumors in the kidneys that can impact quality of life. So it's variable, and some of our adults live independently. Others require more complex care. It's usually diagnosed in childhood and in infancy, either in utero, where you can see two or more heart tumors in a regular ultrasound. Sometimes you're diagnosed after birth, when a baby begins having seizures. Some people aren't diagnosed till they're teenagers with the appearance of angiofibromas or skin tumors on their face. And occasionally, people are diagnosed when they're adults. They have kids of their own, their children are diagnosed with TSC, and then they are subsequently diagnosed with TSC. So it runs the gamut.   Michael Hingson ** 18:31 So it is something that very much is or can be genetic. It is genetic.   Kari Luther Rosbeck ** 18:38 Yes, it's caused by mutations in one of two genes, TSC one or TSC two, on the ninth or 16th chromosome that controls cell growth and proliferation, which is why you see the appearance of non malignant tumors. And that is what impacts all the organ systems. Yeah,   Michael Hingson ** 19:00 and it is not a fun thing, needless to say, to be around or to have, and it's not something that we have control over. Nick, I know does live with his parents. I don't know whether Nick will ever be able to live independently. He does have seizures and sometimes, and it's not predictable, although he's doing a little bit better job of controlling them with medication, but he'll probably always live with someone. But what a wonderful person to have around. Yes,   Kari Luther Rosbeck ** 19:35 he is definitely enjoyable. And that's, I mean, that's the thing about TSC. We have we have independent adults. We have kids, we have semi dependent adults. We have dependent adults. The one thing about our community and our organization is this is a home for everybody.   Michael Hingson ** 19:58 So when did the. See Alliance actually first begin   Kari Luther Rosbeck ** 20:01 1974 so it started with four moms around a kitchen table in Southern California, and two of those four moms are still in touch with the TSC Alliance. I talked to two of our Founding Moms quite frequently. They are very inspirational. They had this tremendous foresight to think about what the community needed or what they would need in the future. So our organization, the TSC Alliance, we actually have a new vision statement as of this year. So our vision statement is the TSC Alliance wants to create a future where everyone affected by TSC can live their fullest lives, and our mission statement is to improve quality of life for everyone affected by tuberous sclerosis complex by catalyzing new treatments, driving research toward a cure and expanding access to lifelong support. What so some of the ways that that we do this, as you know, is to fund and drive research, to empower and support our community, to raise awareness of TSC, because we want to provide the tools and resources and support for those living with TSC, both individuals and caregivers. We want to make sure that as an organization, we are pushing research forward by a research platform that we've helped create through the years, and we want to make sure that people are diagnosed early and receive appropriate care. So it's really important to us to raise awareness in the general public, but also among the professional community.   Michael Hingson ** 21:52 So this is the 50th anniversary of the TSC Alliance. Yes, it is. And I would dare say, based on what you're talking about, there's a lot to celebrate.   Kari Luther Rosbeck ** 22:04 We have so much to celebrate. Michael, there's been so many accomplishments over the years, from the creation of our professional advisory board early on that provided guidance to the organization to today, we have three FDA approved drugs specifically to treat TSC as an organization in 2006 we started the very first natural history database anywhere in the world that still exists today, with over 2700 participants, and that allows us to really understand how TSC progresses through a lifetime, and then we, as an organization, in partnership with a group of our TSC clinics, helped with the first preventative clinical trial for epilepsy in the United States, and that was really to look at Babies with TSC to treat them before the first seizure, to see if we can prevent or delay epilepsy.   Michael Hingson ** 23:07 So So tell me a little bit about the the three different drugs that are available. What? What do they do? Without getting too technical, how do they work, and so on, because, obviously, the tumors are there. And so what do the drugs do to address all of that   Kari Luther Rosbeck ** 23:24 great question, the first approved drug for TSC everolimus is an mTOR inhibitor, mammalian target of rapamycin. So if you remember I talked about the two TSC genes working as a complex to control the genetic underlying genetic pathway. Well, that underlying genetic pathway is mTOR, and there happened to be a class of drugs that was developed to help with organ transplant and anti rejection. Ever roll. This is a synthetic of rapamycin that was found on rap a rap the islands, rap immune island. So what that particular drug has been approved for, and how it works in TSC is to shrink certain types of brain tumors to shrink tumors in the kidneys, and it's also used as adaptive therapy for seizures associated with TSD. So what we know is it is extremely effective, but if you go off the medication, the tumors will grow back. So it's not a cure, but it's moving in the right direction, right second drug that was approved is the first FDA cannabinoid drug, Epidiolex, and that treats seizures associated with TSC. The third approved drug is a topical rapamy. So it treats those skin tumors on the face. I   Michael Hingson ** 25:04 don't know. It's really interesting. Medical science comes up with all these terms that are tongue twisters. How do they do that? You're 100% correct. Oh, it's a fun world. What's on the horizon, what kinds of things are coming that will kind of either enhance what they do or other sorts of medications? Yeah,   Kari Luther Rosbeck ** 25:28 thanks for asking that. So I think for us, in 2019 we put together a really aggressive research, research business plan, and our goal with this was to ultimately the vision change the course of TSC, and so we have a research platform that really helps accelerate drug development. So we fund research grants or young investigators to keep them interested in the field and to generate new ideas. We have a pre clinical consortium where we work with a contract research organization. We've licensed different mouse models that can try drugs for both epilepsy and tumor growth and behaviors, and so that is really built a pipeline of new potential therapies for TSC we also have this clinical research consortium that we work with. We have 74 TSC clinics across the country, of which 17 are centers of excellence, and we're working with our TSC clinics and centers of excellence to when drugs come out of the pre clinical or when companies come to us and they want to institute clinical trials, we will work with them to be in touch with our clinics, to educate our community about what clinical trials are out there, so they know what questions to ask or how to appropriately weigh risk benefit, so that's a really important part of our platform. We also, I mentioned earlier, a natural history database to help us understand how TSC progresses through a lifetime, but also a bio sample repository, so we'll understand why TSC is so different person to person. So with all of those tools working together, what we want to do is ultimately determine how to predict an individual's risk for the many manifestations of TSC so if we knew who was at risk, say, for epilepsy, and we could intervene to delay or prevent epilepsy. Could we do the same with kidney tumors? So that's what I mean about predicting and prevention. We would like to develop biomarkers to help accelerate outcome measures and clinical trials. We would love to have an intervention early on. Remember, I said that we helped start the first preventative clinical trial for epilepsy. You need an intervention to get on the newborn screening panel. If we could be on the newborn screening panel and identify babies early, that is the greatest way to change the course of the disease. Of course, we obviously want to test more compounds in our pre clinical consortium to make sure that we are building that pipeline for new and better drugs in the future, and we definitely want to develop patient reported outcomes. So how does this disease impact quality of life for individuals and families living with it, so that we'll know in the future, if there are different potential treatments, does it impact or improve their quality of life? And the FDA looks at patient reported outcomes quite seriously, so we want to build that for future clinical trials and clinical studies. Finally, one of the biggest unmet needs in TSC is what we call TSC associated neuropsychiatric disorders, or taint This is an umbrella term for brain dysfunction that includes everything from sleep problems to depression, anxiety, aggressive behavior, executive functioning, how people learn. So it is definitely an umbrella term, and almost everybody is impacted by tanned in some way that are living with TSC. So we want to better understand who might be at risk for which parts of tan so that we can intervene and improve quality of life.   Michael Hingson ** 29:55 Something that comes to mind we hear people talking. Think a fair amount today about gene therapy and how all of that might work to cure various diseases and so on. Is there room for that in Tse, since especially it's caused by two specific genes?   Kari Luther Rosbeck ** 30:14 Great question. We actually are working with some gene therapy companies in our pre clinical consortium looking to see if we can intervene that way.   Michael Hingson ** 30:26 It's a few years off, yeah, I can imagine, but it would be an interest if, if it truly can be done, since you're clearly able to tell that there are specific genes that are that are causing this. It's an interesting concept, given the state of science today, to think about whether that could lead to, even if it's not immediate, but later, cures for TSC and other such things, and   Kari Luther Rosbeck ** 30:57 we might start with organ specific gene therapy. For instance, if we had gene therapy early on in the brain, again, thinking about preventing seizures from ever developing, if we were able to implement gene therapy in the kidneys so or lungs so women never develop lamb, that would be a huge breakthrough. Yeah. So thinking about how that might work and how that could impact our community is tremendous,   Michael Hingson ** 31:28 I would think so. And I would think if they are able to do some work in that regard, it would be very revolutionary. And obviously, the more we learn about gene therapy overall, the more it will help with what medical science can do for TSC as well. That's right. So what does the Alliance do for families and individuals? What kinds of specific things do you all do?   Kari Luther Rosbeck ** 31:57 Yeah, we have   32:00 developed 14   Kari Luther Rosbeck ** 32:01 community regions across the country where we work with our volunteers. So they'll in their regions, host community educational meetings, walks, where they bring the community together, which is hugely important offer peer to peer support. So that is on a regional level. On our team, we have support navigators, so people that are available to take calls, emails, texts to really help when people either receive a new diagnosis, will spend a lot of time making sure they get to the right clinics, resources, support systems, or when a new manifestation arises, or if people are having some access to medication or access to care issues, we have a TSC navigator so that is a proactive online tool that people can log into and that will really take them through the journey in a way they want to gain information. So it's really written in in small bites, so that if people want more information, they can dive deeper. That's hugely important for individuals impacted. We have regular webinars, regional conferences, and every four years we hold a World Conference. Well, we will bring in experts from all over the world to cover the many manifestations of TSC so people are informed to make the best decisions for them and their families. They'll also talk about new clinical trials or new research on the horizon, or they're talk about social service tools that are really important for living or guardianship or financial planning, so those things that aren't just medical, but really impact people's lives.   Michael Hingson ** 33:57 So today, what, what do you think? Or how would you describe, sort of the social attitude toward TSC and people with TSC, or is it, is it more manifested in Well, this guy has seizures and so on, so TSC doesn't directly tend to be the thing that society views.   Kari Luther Rosbeck ** 34:22 That's a great question. And because TSC is so variable, I'm going to say to you, it's different person to person. One of the things we did a few years ago was create these little business cards that described what TSC was. So if somebody's out at a restaurant, they might hand it to their waiter or waitress to say, We want you to know that our for instance, our child has TSC and so you understand what you might see as you wait on us. For example, I still think that for those that are more severely in. Acted. I talked about tanned and some folks with more severe behaviors. You know, our society, it's attitude, right? You talked about that in your presentation of diversity to inclusion, we need to be much more understanding when a family is trying to handle a seizure or or behaviors and not pass judgment on that family, let the family handle that situation. So I would just say it's individual to individual, but one of the most amazing experiences, as is at our world conferences, where everybody can just be. And everybody understands that TSC is variable. And you might have a child over here with a seizure dog. You might have an adult group in one corner talking and dancing, but everybody comes together, yeah,   Michael Hingson ** 35:58 yeah. And that's really important to do, and that's you raise a really good point. Obviously, dogs are learning to be better at seizure detection. And I was going to ask about that, because I assume that that certainly can play into helping people who have seizures, who have TSC.   Kari Luther Rosbeck ** 36:18 That is absolutely correct earlier. You asked about what it was like early on, we didn't have a lot of seizure dogs at our early conferences. That's something that really has been happening after, say, 2010 we've definitely seen a lot more seizure dogs be trained and really be helpful to families.   Michael Hingson ** 36:39 Yeah, well, and we have come so far in terms of training dogs to be able to detect seizures and detect so many things. One of my favorite stories, and it's not a seizure detection as such, but one of my favorite stories, is about a Portuguese water dog who was a show dog, but he or she, rather, was also trained to do cancer detection. And the owner, who was very competitive in doing show dog type things, as well as had started a company or a facility to deal with cancer detection, took his dog to the show, to a dog show. And every time the dog got near this one judge, it just laid down. It would not perform, it would not work. And so needless to say, this national champion didn't do very well at that show. And the guy couldn't figure out why. And he got home, and he suddenly realized, oh my gosh, I had taught the dog to lay down whenever it detected cancer, because you don't want to do something dramatic, right? And so he called the woman who was the judge, and he said, Do you have cancer? And she says, No, I don't have anything like that. Then he said, Well, you might go check that out, because and he told her, this was like a Monday when he called her, and Friday she called him back, and she said, I took your advice. And it turns out I have early stage breast cancer. We caught it in time, and it's all because of your dog.   Kari Luther Rosbeck ** 38:04 Oh my gosh, Michael, what an amazing story   Michael Hingson ** 38:10 it is. You know, we we really underestimate our dogs. I know that the first diabetic dog was a dog who who kind of learned it on his own. His person had occasional insulin reactions, and the dog became agitated. And finally, the guy realized, oh my gosh, this dog knows what I'm going to have an insulin reaction. And that led to dogs for diabetics, which is another, of course, sort of same thing that the dogs really can learn to do so many things today.   Kari Luther Rosbeck ** 38:44 Yes, yes, they can.   Michael Hingson ** 38:48 So there's always room for dogs. So we talked, I think, in sort of terms, about your the the whole research platform that you all have developed tell us more about the research platform and what it is and where it's going.   Kari Luther Rosbeck ** 39:06 Well, I definitely talked about all of the tools within our research platform. I think we're certainly taking a deeper dive into all of the tools that that we've developed, when we think about, for instance, our bio sample repository, one of the things we're doing right now is whole genome sequencing. Why? Because we're hoping with whole genome sequencing, we'll understand if there are modifier genes. Are there other things at work that makes some people more severe than other others, and then ultimately, what we'd love to learn is what medications might work best on each individual or personalized medicine, so often in TSC with seizure medications, people end up on a cocktail. We would rather avoid that, right? Wouldn't it be nice to get the medication right the first time? That's really what we are hoping for with our clinical research consortium. Right now, we're doing a couple of quality improvement studies, so one of them is around suit up or sudden, unexpected death from epilepsy, and really understanding the conversations that happen between a physician and a patient or a caregiver, and why aren't those conversations happening in TSC or when are they happening? Because we want to create change so that parents know the risks, or individuals understand the risks, and can they change their behavior to mitigate some of those risks? The other thing that we are doing is we started a reproductive perinatal Health Initiative. This came out of our 2002 world conference because we heard from a bunch of adults that this was a gap for TSC. So TSC is variable. We have some independent adults that may want to start a family someday, but we have no no consensus guide guidance, to guide them in making those decisions. So we put together a group of experts in maternal fetal health, pulmonary nephrology, imaging genetics, to come together to first talk about what are risk stratifications, both for women that are may experiences complications in pregnancy. What are those? What's a risk stratification for each individual? Also, how do we handle perinatal health? How do we care for fetuses of women with TSC, or fetuses where they have been diagnosed with TSC, and what are those recommendations and steps? So that's a real focus for us at our organization, really filling the gaps where those exist. So that's a couple of the things that that I would mention.   Michael Hingson ** 42:16 An interesting question that comes to mind, do you see prejudices or misconceptions that cause difficulties within medical science. And I ask that because I know from a blindness standpoint, so often, when a person goes into an ophthalmologist because they're having eye problems, they go in and the doctor will say, eventually after diagnosis, well, you have retinitis pigmentosa, you're going to go blind. There's nothing I can do, and literally, just walk out of the room without ever dealing with the fact that this person can still be a very normal person. Do you see any of that kind of stuff in the world of TSC so   Kari Luther Rosbeck ** 42:56 early on, less today, but we still hear about it when people are handed the diagnosis of TSC, they it could be very cold. Physicians would say, your child will never walk, they'll never talk, they'll never live a normal life. That's horrible, like you're taking away that hope. And that may not be the case for each individual with TSC, I think some of our families, when their infants begin to have a devastating type of seizure called infantile spasms that can look just like a head nod, sometimes they are misconstrued for indigestion or startle reflex, and They try to get care for their baby, they're told that they're just being paranoid and crazy. It's nothing, but the it's up to the parents right to continue to advocate, because they know something is not right and that that is the right course of action. And then for adults, I think sometimes our adults living with TSC really struggle with adequate care. We've done a really good job of pediatric care specifically for TSC, but as a country, we could do a lot more for those with developmental disabilities, including TSC and providing adequate transition from adult care, these are the places that I see prejudice or roadblocks put up for our families.   Michael Hingson ** 44:33 How do you teach or what do you do to teach parents and adults, especially about being stronger advocates.   Kari Luther Rosbeck ** 44:43 Well, first of all, we tell them to trust their instincts and trust their voice and to not give up if you're hitting a roadblock. One place call us. Maybe there are other other clinical care that we can provide for you. Yeah. If you're having an issue at work, it's really important that you get the right support to advocate for yourself, but to never, ever give up, ever give up.   Michael Hingson ** 45:11 Yeah, that's really, of course, the important part, because ultimately, and I think it's true for most all of us, we know ourselves better than anyone else. And as parents, we know our children better than anyone else, and certainly should never give up and work very hard to be strong advocates to support what their needs are and support them to grow and advance.   Kari Luther Rosbeck ** 45:36 That's exactly correct,   Michael Hingson ** 45:41 and it needs to happen a whole lot more, because all too often, I can imagine hearing people say, well, it's nothing, it's just your it's your imagination. Well, no, it's not, you know, but we see way too much of that kind of thing happening in the world. So it's great that that you're able to do so much. What about in the in the professional world, or in just dealing with people and their lives? What? What kind of things are you able to do to, let's say, help support somebody who wants to go out and get a job?   Kari Luther Rosbeck ** 46:21 Sure? We point them to local resources that might be an expert in that. We also have navigation guides that might help them, that are a supplemental resource to our TSC navigator. We have adult topic calls and adult open forums so that they might also get guidance and advice from their peers that have walked that journey. So those are some of the resources that we will help people who want to get a job   Michael Hingson ** 46:55 do Centers for Independent Living help.   Kari Luther Rosbeck ** 47:00 Are you familiar with those? No, I'm not familiar. Sorry, I'm not familiar. So the   Michael Hingson ** 47:04 CIL system is a system of independent living centers. It really started, I don't know, but I think in Berkeley, it's centers that teach and advocate for the whole concept of being able to live independently, and deals a lot with physical disabilities, and I'm not sure how much the developmental disability world interacts in the CIL it may be a lot more of a physical thing than anything else.   Kari Luther Rosbeck ** 47:32 Well, always great to have new resources that we can share with our community. It's worth   Michael Hingson ** 47:38 exploring Absolutely, because it could very well lead to something that would be helpful, not sure, but it's always worth exploring. The arc is   Kari Luther Rosbeck ** 47:47 another organization I was gonna ask about that frequently. Yes, we've, we've had a partnership with the arc in the past. Many of our community regions obviously work with local arc chapters. It is a partnership that we truly value, and they have a ton of resources that are available for individuals, seeking jobs, seeking Independent Living, seeking so or housing for families. So we don't need to replicate what somebody is already doing. Well, we will partner with that organization,   Michael Hingson ** 48:25 and that makes sense. There's no sense in replicating. It's all about collaborating, which makes a lot more sense to do. Anyway,   Kari Luther Rosbeck ** 48:33 exactly we agree.   Michael Hingson ** 48:36 Well, so what are so, what are your your sort of long term goals from here? Oh,   Kari Luther Rosbeck ** 48:45 long term goals from here? Well, we want to continue to improve quality of life for everyone. We want to make sure that there is adequate transition between childhood and adult in terms of medical care, independent living, or housing or schooling, or whatever that transition may employ, we really want to make sure that we continue the pipeline of new treatments. We want to drive towards a cure. We want to support and empower every family living with TSC. One of the things that we've really been able to do because of advocacy, is to grow the TSC research program at the Department of Defense. So this is a congressionally directed medical research program. There's been an appropriation for TSC since fiscal year, 2002 and cumulatively, 221 million has been appropriated for TSC research. We want to continue to grow that. But on a state level, we've also had some success in growing state funding for. TST clinics in particular states, and for TSC research at those institutes. So over 5.7 5 million have been advocated, have been appropriated from the states of Maryland and Missouri and Michigan and Alabama. So very excited about continuing to grow that that program, as I mentioned, I think getting on the newborn screening panel would be a game changer for TSC, complete game changer. And we want to continue to grow our advocates and grow those that are available as leaders in their communities to offer support to others.   Michael Hingson ** 50:39 So the funding comes through the Department of Defense. Why is that?   Kari Luther Rosbeck ** 50:44 It is a program that is high risk, high reward. You have to have some military relevance. So so for TSC, obviously, our connection to epilepsy and our mass models that are used for developing epilepsy medications, those mass models can also be used to look at traumatic brain injury. So that's a connection. It's high risk, high reward. So understanding the underlying biology of TSC and finding that genetic pathway that I mentioned was one of the hallmark achievements early on of this program. So it's, it's, it is so amazing. The early gene therapy work for TSC started at the TSC research program at the Department of Defense.   Michael Hingson ** 51:33 And I gather you're probably getting a lot of really good support from DOD. So   Kari Luther Rosbeck ** 51:38 it doesn't come to the TSC Alliance, we advocate to make that funding available to researchers around the country. So we think of that as part of our mission for driving research. But we don't see a dime of that. Those dollars, they all go through Fort Detrick and through the Department of the Army, right? The other cool thing, though, Michael is we nominate consumer reviewers, so people that help advocate for these funds also sometimes get a seat at the table to say what research would be meaningful for their lives as a consumer. And that is a really cool, unique thing that happens.   Michael Hingson ** 52:21 Yeah, well, and I was asking about support, I was thinking more of their they're perfectly willing and pleased to be a part of this, and are really open to helping and really contributing to the research, because I would think it would help all the way around 100%   Kari Luther Rosbeck ** 52:40 and the one thing is the TSC Alliance, the DOD and NIH. We all work together so that we're not duplicative. But we have, there was a research strategic plan that was developed out of a workshop at NIH that we all follow as kind of our guiding principle. We all do different things, and we all complement each other. So out of that NIH plan, for instance, a bio sample repository and preclinical consortium was recommended, and recommended that the TSC alliance is the patient advocacy group, be the one that started that and continues to make sure that those resources continue. That's just an example. Obviously, DOD does high risk, high reward. And NIH, you know, the prevent trial that I mentioned, the first preventative trial for epilepsy in United States, was funded by the National Institute of Neurological Disorders and Stroke. We helped educate the community so that people would want to participate.   Michael Hingson ** 53:46 Well, it's, I think, important and relevant to ask, how can people get involved? What can the rest of us all do?   Kari Luther Rosbeck ** 53:54 Oh my gosh, I'm so glad you asked. Well, please go to TSC alliance.org, learn more about the organization. Become a volunteer. Help us. Help us with our walks, help us with our conferences. You can certainly get involved. If you're an individual with TSC and you want to get connected through social media, you can go to Facebook, Instagram, LinkedIn, YouTube, even Tiktok at the SC Alliance, we have very active discussion groups Michael that offer peer to peer support. 24/7 especially on Facebook, it is a private group, and those group of individuals and families have been so supportive for anyone walking this journey, you can call us at 1-800-225-6872, if you need support, you can ask for a support navigator. If you're interested in helping us with fundraising or making a donation, you can ask for our development department. If you want to volunteer, ask for. Community programs, we want all takers, and we're always also happy to talk with any organization, any nonprofit, that's wanting to pull together their programs, seek advice or work as a partner,   Michael Hingson ** 55:15 and what's the phone number? Again? 1-800-225-6872,   Michael Hingson ** 55:24 and the website is TSC   Kari Luther Rosbeck ** 55:26 alliance.org,   Michael Hingson ** 55:29 cool. Well, I've asked lots of questions. Have I left anything out? Any other things that you think we ought to cover? I   Kari Luther Rosbeck ** 55:37 think you did a great job. I would just say if anybody wants to join us at our 50th Anniversary Gala, we'd love to have you. TSD alliance.org, backslash 50 Gala. We will be celebrating october 25 at ciprianis in New York City, and we'd love to have you with us. Ooh, that sounds like it'd be fun. I know you gotta get your family to bring you this time. Well, yeah,   Michael Hingson ** 56:07 if they're going to come, they should, should take me. I'm trying to think, I don't know whether I'll be anywhere near there at the time, but my schedule changes all the time, so it's sort of like everything else you never know. But I will keep that in mind, because it would be fun to come and get to meet you in person. I would love that. Well, I want to thank you for being here with us. This has been, needless to say, very educational and very enjoyable. And of course, as you know, I have the personal stake of a great nephew, but just being able to talk about it, to hear the progress that's being made as, I think, really crucial and really important to be able to let people be aware of and I hope that people who do hear this will get involved, will at least learn more about it. Have you written any books or anything? I have   Kari Luther Rosbeck ** 56:57 not written any books. Oh, we got to get you to work. That's right, you're an inspiration.   Michael Hingson ** 57:04 Well, something to work on. You should? You should write a book about it all. That'd be a new project. It's not that you don't have enough to do, though. That's   Kari Luther Rosbeck ** 57:13 right. Michael, I'm too busy taking care of our community right now, but when I retire, that might be something I think about. Well, there   Michael Hingson ** 57:21 you go. Well, I want to thank you again for being here. This has been, I will say, enjoyable, but it's been most educational. I've learned a lot, and I appreciate your time, and I hope that, as I said, everyone else has as well. So I want to thank you for being here, and anytime in the future you want to come back and talk some more about what's going on and tell us about other new, revolutionary changes and so on. You are always welcome.   Kari Luther Rosbeck ** 57:46 Thank you. Michael, I'd love to come back. Well, thank   Michael Hingson ** 57:50 you again, and let's do it anytime you'd like, Okay, you got it.   **Michael Hingson ** 58:01 You have been listening to the Unstoppable Mindset podcast. Thanks for dropping by. I hope that you'll join us again next week, and in future weeks for upcoming episodes. To subscribe to our podcast and to learn about upcoming episodes, please visit www dot Michael hingson.com slash podcast. Michael Hingson is spelled m i c h a e l h i n g s o n. While you're on the site., please use the form there to recommend people who we ought to interview in upcoming editions of the show. And also, we ask you and urge you to invite your friends to join us in the future. If you know of any one or any organization needing a speaker for an event, please email me at speaker at Michael hingson.com. I appreciate it very much. To learn more about the concept of blinded by fear, please visit www dot Michael hingson.com forward slash blinded by fear and while you're there, feel free to pick up a copy of my free eBook entitled blinded by fear. The unstoppable mindset podcast is provided by access cast an initiative of accessiBe and is sponsored by accessiBe. Please visit www.accessibe.com . AccessiBe is spelled a c c e s s i b e. There you can learn all about how you can make your website inclusive for all persons with disabilities and how you can help make the internet fully inclusive by 2025. Thanks again for Listening. Please come back and visit us again next week.

#792: New Year, New Goals – Make 2025 Your Best Year Yet! Join Michael & Lauryn Bosstick as they sit down to discuss their goals & intentions for the New Year, sharing actionable habits & meaningful changes to inspire your own journey. They cover everything from setting personal boundaries, managing phone usage, adopting mindset shifts, implementing strategic planning, & building a framework to unlock your full potential. Start 2025 with a purpose & learn how you can make it your most impactful year!   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697)   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   Visit c1p.org to donate to the Community First Project, a mission to make communities safer by ensuring the quality & integrity of our nation's law enforcement agencies.   This episode is sponsored by Cymbiotika    Go to Cymbiotika.com/TSC or use code TSC for 20% off your subscription order + free shipping today.   This episode is sponsored by O Positiv   Visit opositiv.com and use code SKINNY at checkout for 25% off at checkout.   This episode is sponsored by Oura    Visit ouraring.com.   Produced by Dear Media

#791: Join us as we sit down with Dr. Rangan Chatterjee – one of the UK's most renowned medical doctors, boasting over 20 years of experience, & author of 5 internationally best-selling books. Dive into insights from, Dr. Chatterjee's latest book, Make Change That Lasts, where he reveals the 9 simple ways to break free from the habits that hold you back. In this episode, Dr. Chatterjee discusses the power of connection & community, the impact of setting morning intentions, the four pillars of health & their profound influence on your lifestyle, & daily mindset practices that can transform your life!   To connect with Dr. Rangan Chatterjee click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697)   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   This episode is sponsored by Nutrafol   For a limited time, Nutrafol is offering our listeners $10 off your first month's subscription and free shipping when you go to Nutrafol.com and enter the promo code SKINNYHAIR.   This episode is sponsored by TravisMathew   Consider TravisMathew your holiday headquarters, and discover the perfect gift for everyone on your list. Visit travismathew.com and receive 20% off your order with code SKINNY.   This episode is sponsored by YNAB   TSC Him & Her Show listeners can claim an exclusive three-month free trial, with no credit card required at YNAB.com/skinny.   This episode is sponsored by Noom   Start your GLP-1 journey today at Noom.com.   This episode is sponsored by Cymbiotika   Go to Cymbiotika.com/TSC or use code TSC for 20% off your subscription order + free shipping today. Produced by Dear Media

#789: Join us as we sit down with Marcy Blum – a world-renowned event planner, and entertaining expert, named by VOUGE & Harper's Bazaar as the Top Planner in the World. Discover behind-the-scenes stories from some of the most extravagant weddings ever, spanning A-list celebrities to the ultra-wealthy, & everyone in between! In this episode, Marcy shares her expert advice on wedding do's & don'ts, must-haves for hosting a flawless event, tips for staying realistic with your budget, & eye-opening revelations about the luxury wedding industry.   To connect with Marcy Blum click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   To Watch the Show click HERE   For Detailed Show Notes visit TSCPODCAST.COM   To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697)   This episode is brought to you by The Skinny Confidential   Head to the HIM & HER Show ShopMy page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   Visit c1p.org to donate to the Community First Project, a mission to make communities safer by ensuring the quality & integrity of our nation's law enforcement agencies.   This episode is sponsored by O Positiv   Visit opositiv.com and use code SKINNY at checkout for 25% off at checkout.   This episode is sponsored by NOBULL   Exclusively for The Skinny Confidential listeners, NOBULL is offering 30% off your order. Visit nobullproject.com and use code TSC30.    This episode is sponsored by Sono Bello   Schedule your free consultation now at sonobello.com/skinny.   This episode is sponsored by Cymbiotika   Go to Cymbiotika.com/TSC or use code TSC for 20% off your subscription order + free shipping today.   This episode is sponsored by ShipSkis   Go to Shipskis.com and use the code SKINNY to get 20% off your first shipment and save yourself the hassle this ski season.   This episode is sponsored by Cotton: The Fabric of Our Lives   Cotton is The Fabric of Now. Learn more at TheFabricOfOurLives.com.   Produced by Dear Media

In this episode of TSC Now host Dan Klein is joined by Bruce Hainan and Jim Kotsailidis from Nobelpharma America, LLC and Shelly Meitzler, TSC Alliance Director of Outreach and Support, and mom to Ashlin and Mason with TSC. Shelly shares her experience looking for housing for her eldest daughter Ashlin, a dependent adult with tuberous … Continue reading Navigating Housing Options for Dependent Adults with TSC (sponsored by Nobelpharma America) →

IntroductionLIVE from your ESG-powered Vitamix A3500 Ascent Series Smart Blender, it's a Business Pants Friday Show here at December 13th Studios, featuring AnalystHole Matt Moscardi. On today's weekly wrap up: Ongoing NEO murder stuff, Rupert Murdoch fails to screw over 75% of his children, God eats McDonald's, and hot sauce is going wokeOur show today is being sponsored by Free Float Analytics, the only platform measuring board power, connections, and performance for FREE.Story of the Week (DR):NEO shooter, continued MMUnitedHealth Group CEO addresses Brian Thompson death, says healthcare system is 'flawed'“a brilliant, kind man who was working to make health care better for everyone”No proof of that, of course“When a colleague proposed a new idea to Brian, he would always ask, “Would you want this for your own family?” If not, end of discussion.”Also, really?“His dad spent more than 40 years unloading trucks at grain elevators. B.T., as we knew him, worked farm jobs as a kid and fished at a gravel pit with his brother.“See, he's one of youFoxbusiness and foxnews is referring to Luigi as “ivy league graduate Luigi Mangione”“The ideas he advocated were aimed at making health care more affordable, more transparent, more intuitive, more compassionate — and more human. That's Brian's legacy, one that we will carry forward by continuing our work to make the health system work better for everyone.”His other legacy is TSC of $30M over past 3 years and roughly $40M in equity“we also are struggling to make sense of this unconscionable act and the vitriol that has been directed at our colleagues who have been barraged by threats. No employees — be they the people who answer customer calls or nurses who visit patients in their homes — should have to fear for their and their loved ones' safety.”Amazing deflection because people are clearly angry at the… EXECUTIVESBut maybe he DOES understand the vitriol:“We know the health system does not work as well as it should, and we understand people's frustrations with it.”“Clearly, we are not there yet. We understand and share the desire to build a health care system that works better for everyone.”“Health care is both intensely personal and very complicated, and the reasons behind coverage decisions are not well understood. We share some of the responsibility for that.”“No one would design a system like the one we have. … Our mission is to help make it work better.”It's true, that's basically their hollow mission statement. And I suppose massive profit helps with that goal?UnitedHealth Group annual gross profit for 2023 was $90.958B, a 14.24% increase from 2022.UnitedHealth Group annual gross profit for 2022 was $79.617B, a 14.31% increase from 2021.UnitedHealth Group annual gross profit for 2021 was $69.652B, a 3.96% increase from 2020.There's also this part of their mission statement: “We dedicate ourselves to this every day for our members by being there for what matters in moments big and small — from their earliest days, to their working years and through retirement.”Which doesn't exactly gel with: UnitedHealthcare's claim denial rate is 32%, which is higher than the industry average of around 17%UnitedHealthcare CEO shooting suspect arrested; charged with murderLuigi Mangione wasn't a UnitedHealthcare member, may have targeted company because of size and influence: NYPDUnitedHealth Group CEO says slain exec Brian Thompson was ‘one of the good guys' in leaked memo to 400,000 employeesFormer Aetna CEO says he'd eliminate employer-sponsored insurance to fix the U.S. healthcare industry in wake of UnitedHealthcare shootingUnitedHealthcare CEO's death is being mocked on LinkedIn—a move that could hurt careers, says HR expertRupert Murdoch Fails in Bid to Change Family Trust A Nevada commissioner has ruled against Rupert Murdoch's legal attempt to alter his family trust so that his eldest son, Lachlan Murdoch, will control the family's media and business empire when he diesBarring a successful appeal, the decision ensures Murdoch's media empire will be left equally to his four oldest children, who are not all ideologically aligned with the conservative views of Rupert and Lachlan.Notably, James Murdoch — once considered a contender to take over the family business — resigned from the board of News Corp. in 2020, citing disagreements over editorial content published by the Wall Street Journal and the New York Post.U.S. appeals court tosses Nasdaq diversity rules for company boardsThe conservative-majority New Orleans-based 5th U.S. Circuit Court of Appeals ruled the Securities and Exchange Commission did not have the power to approve the rule that required companies to ensure women and minority directors were on their boards or provide an explanation of why this was not the case.It was implemented after George Floyd's killing pushed companies to address racial inequality and move toward diversity, equity and inclusion.CEO Buddy System: Deloitte survey: CEO optimism ‘is as high as we've ever seen'Trump's inaugural fund receives $1 million donation from Mark Zuckerberg's MetaOpenAI CEO Sam Altman to donate $1 million to Trump's inaugural fundJeff Bezos' Amazon Plans to Donate $1 Million to Trump's InaugurationElon Musk Gloats as Trump Announces Billionaires Will Be Exempt From Normal Environmental RulesOn Tuesday, president-elect Donald Trump announced in a Truth Social post that any "person or company" investing $1 billion or more in the US would "receive fully expedited approvals and permits, including, but in no way limited to, all Environmental [sic] approvals."Goodliest of the Week (MM/DR):DR: California bill would require mental health warning labels on social media California Attorney General Rob Bonta is pushing for social media companies to be required to post mental health warnings on their sites.DR: Paris is replacing 60,000 parking spaces with trees MMMM: Stanley recalls 2.6M travel mugs due to potential burn hazard from faulty lidsAssholiest of the Week (MM):Andrew Witty DRUnitedHealth Group C.E.O.: The Health Care System Is Flawed. Let's Fix It.We know the health system does not work as well as it should, and we understand people's frustrations with it. No one would design a system like the one we have. And no one did. It's a patchwork built over decades. Our mission is to help make it work better. Clearly, we are not there yet. We understand and share the desire to build a health care system that works better for everyone. That is the purpose of our organization.Health care is both intensely personal and very complicated, and the reasons behind coverage decisions are not well understood. We share some of the responsibility for that.While the health system is not perfect, every corner of it is filled with people who try to do their best for those they serve.Brian was one of those people. The ideas he advocated were aimed at making health care more affordable, more transparent, more intuitive, more compassionate — and more human.Meanwhile…How UnitedHealthcare and other insurers use AI to deny claimsLeaked video shows UnitedHealth CEO defending practices that prevent ‘unnecessary' careAccording to ValuePenguin, a site that helps users compare insurance plans' costs, UnitedHealth's 32% claims denial rate was twice the industry average. Congress Introduces Bills to Break Up UnitedHealth Groupsponsored by Senators Elizabeth Warren (D-MA) and Josh Hawley (R-MO), Dual class investorsNon profits have figured something out capital markets haven't - you can't make dual class non profits: Rupert Murdoch Fails in Bid to Change Family TrustAt one point in his 96-page opinion, Mr. Gorman characterizes the plan to change the trust as a “carefully crafted charade” to “permanently cement Lachlan Murdoch's executive roles” inside the empire “regardless of the impacts such control would have over the companies or the beneficiaries” of the family trust.In a statement, James, Elisabeth and Prudence said: “We welcome Commissioner Gorman's decision and hope that we can move beyond this litigation to focus on strengthening and rebuilding relationships among all family members.”The initial trust arrangement was meant to be binding, the product of an agreement Mr. Murdoch negotiated with his second wife, Anna — the mother of Lachlan, Elisabeth and James — who was concerned that he would bequeath an equal share of control and equity to the young children he had with Ms. Deng. AND YET… we tolerate dual class dictatorships in capital markets in perpetuity?“Carefully crafted charade[s]” designed to keep a company's control private but siphon money from markets anywayOhioSB6The board, in accordance with its fiduciary duties described under this section, shall make investment decisions with the sole purpose of maximizing the return on its investments. The board shall not make an investment decision with the primary purpose of influencing any social or environmental policy or attempting to influence the governance of any corporation.That's literally the ONLY thing you get as an owner of stock - the ability to vote, which in and of itself is influence over governance of a corporation So no Ohio pension funds CANNOT VOTE AGAINST MANAGEMENT! EVER! BY LAW! NO MATTER WHAT!Small businessThe normies feel good… … and lose every timeHeadliniest of the WeekDR: How McDonald's was involved in almost every major news story this past yearCustomers' boycotts topple McDonald's Q1 salesIn October 2023, the McDonald's Israel franchise made headlines for giving away free meals to IDF soldiers involved in the escalating Israel-Hamas War—resulting in a massive boycott by pro-Palestinian protestors in the Middle East. Inflation plagues consumers and McDonald's prices soarMcDonald's faced another backlash this year over its $18 Big Macs, leaving many price-conscious customers questioning whether it was still worth the cost. Faced with inflation and the high cost of living, customers just weren't having it.In order to counteract the bad publicity it was receiving, McDonald's rolled out a $5 meal deal which seemed to win over at least some customers and gave the stock a boost as Americans came back for the more affordable burgers.McDonald's Quarter Pounders linked to an E. coli crisisIn a year with more than 300 food recalls, none seemed as well publicized, or as lamented, as the McDonald's Quarter Pounder recall in October. The fast-food chain's stock price plummeted after it became the center of a full-on E. coli outbreak, linked to onions on its Quarter Pounders. In the end, a significant number of people were affected across 14 states: 104 people became sick, 34 were hospitalized, and one person died.Trump serves fries at McDonald's on the campaign trailMcDonald's also played a role in the 2024 presidential campaign, when then-Republican nominee Donald Trump tried his hand at operating the fry machine at one of the fast-food giant's Pennsylvania locations and held a press conference at the drive-thru window. The visit was largely seen as a way to counter, without evidence, stories of Democratic nominee Kamala Harris's having worked at McDonald's one summer while in college.RFK Jr brutally mocked over ‘MAHA' hypocrisy as he enjoys McDonald's ‘really bad' meal with TrumpLuigi Mangione is arrested in a Pennsylvania McDonald'sWhen law enforcement officials first arrested Luigi Mangione, the 26-year-old suspect in the killing of UnitedHealthcare CEO Brian Thompson, many people were surprised that Mangione, who had alluded police for five days, was found at a McDonald's in Altoona, Pennsylvania.MM: BuzzFeed survives by selling 'Hot Ones' to George Soros MMVivek Ramaswamy, winner of the Paul & Daisy Soros scholarship, still owns a 9% stake in the A shares of the dual class companyWho Won the Week?DR: Two winners:Directors who resign in protest: James Murdoch — once considered a contender to take over the family business — resigned from the board of News Corp. in 2020, citing disagreements over editorial content published by the Wall Street Journal and the New York Post.CEOs who take over companies from founders while the founder stays as Executive Chair: Oracle CEO Safra Catz Plans to Sell Over $1 Billion of StockMM: Billionaires who need permitsPredictionsDR: The next McDonald's headline: Shareholders Sue OpenAI's ChatGPT after the Chatbot Coaxed a Troubled Chief Revenue Officer to Eat 850 Quarter Pounders during Last Month's Nor'easterMM:

Today we talk about five things that most homesteaders deprioritize in their preps as well as out usual Monday segments. Featured Events - an update Sponsor 1: DiscountMylarBags.com Sponsor 2: EMPShield.com, Coupon code for $50 off - LFTN Livestream Schedule Tuesday, 9:30am: Coffee Chat with John Willis and Jack Spirko Friday, 9:30am: Homestead Happenings for November 8, 2024 Tales from the Prepper Pantry Best year ever for meat organization - what worked  Harvest chili Weekly Shopping Report Aldi was our only stop this week.  They still have not restocked wet cat food, in fact I'm not even sure I saw the individual cups.  They did have a normal amount of toilet paper.  The chocolate I like was back in stock after being gone last week, but there wasn't much of it.  Staple prices were: bread (20 oz. white): $1.39 (the tag was back); eggs: $2.15 (-); whole milk: $2.88; heavy cream: $5.39; OJ: $3.45; butter: $3.99; bacon: $3.99; potatoes: $3.59 (-); sugar: $2.99; flour: $2.35; and 80% lean ground beef: $4.49. I did check the online price of a 2x4x8 at Home Depot, and it is still $3.85. A gallon of untainted regular gasoline remains at $3.599. Frugality Tip Halloween is my favorite holiday. We have a big Halloween party every year. I try to pick the theme in advance and then start gathering decorations when Halloween items go on clearance. For Halloween clearance shopping this year (so far) we got $300 retail value of items for less than $100. So hit the stores after the holiday and get more bang for your buck.  Happy savings y'all Operation Independence Cheese Class and Other Events Main topic of the Show: Five Oft-Overlooked Preps For The Homesteader With all the unrest in the economy, looming worldwide war, accelerating technology and the push from the ruling class (for lack of a better term) to keep we peons unhealthy, just in debt enough that we are too scared to go our own way, and obsessed with the “two” options that are the “only” options so that we fight with ourselves instead of see the true enemy, is it any wonder that, more and more, people want to get out of the cities and homestead? In a disaster a homestead is where you want to be, right? When you homestead, you go all in on Bugging In. 2 is 1 Appalachia and resilience - it's not just that it is rural. It is forgotten, abused, walked on, and easily cut off so people there rely on one another already Typical homestead journey: chickens, garden, canning, wood heat, bigger livestock, hobbies like spinning or woodworking or whatnot. Homesteaders have food covered - sort of. When was the last time you went to the feed store? Mindset shift: prepare for the most likely problems, not wwIII and you will weather wwIII better than if you “prepare” for it. FIVE OVERLOOKED PREPS Medical: Supplies for humans and livestock TRAINING, EDC - what do you have on you, Organization Bugging Out: Your plan is to bug in. Heck, my plan is to bug in. What is your plan if you have to leave quickly? Where are you going? How are you getting there? What will you use to travel? What about your livestock? Security: Beyond carrying a gun. TRAINING. What is the plan (who does what) if there is a two legged threat. What about four legged problems? How hard is it to get to your place? (Thorny hedges, security fencing, etc) Do you know when someone is coming? Can you fight if you have to? Like can you really? Food for livestock: Be honest. What is the plan? What is it if you can't just fall back on TSC? How do you regenerate the food? And be honest? How much do you rely on the grocery store for humans. (Community Connections/Underground Network) Fitness: Can you do everything needed by hand? Are you healthy? What is your plan to get healthy? Is everyone in your family fit? (Dedicated space, nutrition, living apothecary,) Communication (Bonus item): Does everyone KNOW what the plans are, know where things are, also get training, know how to communicate if you bug in vs bug out? As a homesteader you are likely more prepared in many ways than preppers in the city with lots of stuff and no skills, but how do we weather things for real? By getting better one day at a time and by eating the frog that we are avoiding so that we dont end up in a situation where we need a skill we could have built and we just didnt because it was distasteful. Make it a great week! GUYS! Don't forget about the cookbook, Cook With What You Have by Nicole Sauce and Mama Sauce.    Community Follow me on Nostr: npub1u2vu695j5wfnxsxpwpth2jnzwxx5fat7vc63eth07dez9arnrezsdeafsv Mewe Group: https://mewe.com/join/lftn Telegram Group: https://t.me/LFTNGroup Odysee: https://odysee.com/$/invite/@livingfree:b Resources Membership Sign Up Holler Roast Coffee Harvest Right Affiliate Link  

Lance Haun, TSC's VP of Market Insights, joins Jess and Jason to chat about AI and EX. For more than a decade, Lance has been focused on all things HR, recruiting and talent management technology. So, what's on his mind lately? Lance wonders if we've taken a step back from employee experience. “Is AI the antidote or poison (maybe a bit of both)?”  Let's get into it! 

Want a quick estimate of how much your business is worth? With our free valuation calculator, answer a few questions about your business and you'll get an immediate estimate of the value of your business. You might be surprised by how much you can get for it: https://flippa.com/exit -- In this episode of The Exit: Andrew Dickow, Managing Director at Greenwich Capital Group, shares insights from both the buy and sell sides of mergers and acquisitions. Andrew discusses valuation methodologies, focusing on the importance of clean financials and understanding market multiples. Specifically in the food and beverage industry, he introduces his "40/20 rule" as performance benchmarks to receive an attractive valuation: 40% gross margins and 20% EBITDA margins. He explains leveraged buyouts, highlighting their benefits to both parties involved in the deal while cautioning about the risks of over-leveraging. He also advises entrepreneurs to be wary of unsolicited offers from private equity firms and emphasizes the importance of hiring proper advisors to run a competitive process. Regarding timing, Andrew notes a recent boom in M&A activity due to anticipated lower interest rates and potential tax implications. For more details and insights, listen to the latest episode of The Exit. -- Andrew Dickow is a Managing Director at Greenwich Capital Group and Townsend Street Capital with over 18 years of experience in both mergers and acquisitions and business operations. Andrew leads the Food and Beverage/Consumer practice for GCG and TSC and has significant experience working with consumer-packaged goods, distribution, contract manufacturing, and ingredient companies. Andrew focuses on both the sell-side and buy-side and has advised numerous clients through recapitalizations, leveraged buyouts, business valuations, and financial analyses. Website: https://greenwichgp.com/ LinkedIn: https://www.linkedin.com/in/andrewdickow/ Check Out Flippa's Data Insights Tool: https://flippa.com/data-insights -- The Exit—Presented By Flippa: A 30-minute podcast featuring expert entrepreneurs who have been there and done it. The Exit talks to operators who have bought and sold a business. You'll learn how they did it, why they did it, and get exposure to the world of exits, a world occupied by a small few, but accessible to many. To listen to the podcast or get daily listing updates, click on flippa.com/the-exit-podcast/

In Episode 89, we sit down with Nune Stepanyan, DNP, FNP-C, CEO, Founder & Aesthetic Injector at The Stepanyan Clinic in Encino, CA. Nune began her career in Critical Care, and while she made the jump to Aesthetics many years ago, her traditional medical roots run deep! While she's a rising star in the injectable world, she approaches her patients and her treatment philosophy with a clinical mindset; that means saying NO or referring out, spending more time on Patient education, and setting realistic expectations that may impact revenue today but result in a lot less headaches tomorrow! In addition to her role as a CEO and a full-time injector at TSC, she's also teaching and training others- a passion she found early on in academia. And she's really good at it! She's currently one of the headliners of the national Revanesse tour with Prollenium going city to city to share her techniques. She's leading cadaver labs, doing in-practice training and consulting, and she made her Aesthetic Next debut this year in multiple talks. In every lecture, it's clear that Nune is a truth teller. She's authentic and unafraid to call out the parts of the industry that seem to jeopardize patient safety or optimal outcomes. She's also a master content creator and has a passion for using her platform to authentically educate, inform and excite others about aesthetic procedures. Tune into her IG any day of the week, and you can find her spilling at least a little tea about the realities of the aesthetics industry! But she credits her candor and real-talk approach to creating trust with her patients and allowing them to feel confident in her ability to deliver great results. Some of Our Favorite Episode Highlights: • Industry Culture: How Nune navigated and transformed challenging industry dynamics and a “mean girl” experience into a platform for authenticity and inclusivity • Ethical Practice: The importance of saying "no" to inappropriate treatments, prioritizing patient well-being over profit, and erroring on the side of caution • Social Media and Aesthetics: Balancing online presence with clinical excellence in the digital age. You really can do both at the same time! • Safety First: Addressing the dangers of unlicensed procedures and DIY treatments and our obligation to keep bad actors out of our specialty • Personal Experience: How her decision to forgo injectables and choose surgery at 35 took her consults to the next level • Business Growth: Insights on expanding to a second clinic location while managing a busy schedule, the finances, and Instagram vs. Reality expectations • Continuous Learning: The value of ongoing education and conference attendance for experienced practitioners to stay innovative and connected in a rapidly evolving specialty • Patient Education: Creating transparent, informative content to build trust and expertise in the field but make it fun, trendy, and sometimes viral! Nune shares her own journey through imposter syndrome, weight issues, mean girls and more, and she's come through it all with her authentic self still intact and zero concern that she's changing who she is to fit anyone's narrative! Her commitment to ethics and patient safety are at the forefront as she navigates the complex world of medical aesthetics with grace, humor, and a dash of sass and brings us all along for the journey. This episode will inspire you and provide a healthy dose of truth moments whether you're an aspiring injector, established practitioner, and anyone finding their way in the evolving world of medical aesthetics. Tune in to hear Nune keep it real in an industry that can be anything but transparent. Warning: Side effects may include a few “hell yeah,” moments of shock, awe and pure entertainment, and a newfound respect for speaking the truth! Learn more about Nune and The Stepanyan Clinic: Instagram: https://www.instagram.com/thestepanyanclinic/?hl=en Website: https://www.thestepanyanclinic.com/

This is a Defcon 1 call for Patriots to save the Republic. The threats against us all have never been sop great or so harmful. Mpox vax, Replicon vax, the coming (stolen) election and the increasingly real possibility of WW3 with Russia. It's all upon us, and the normies are still sound asleep. Sound the alarm patriots, Christopher James certainly is. Thanks for tuning in.   Get the NANO-TECH & Heavy Metals out of your blood w/ Master Peace https://masterpeacebyhcs.com/?ref=4094   MasterPeace Research Study Results: https://www.drrobertyoung.com/post/masterpeace-zeolite-z-research-study-found-to-be-safe-and-effective   The Secret Covenant https://ia804602.us.archive.org/4/items/tsc_7/TSC.pdf   Chris' website: https://awarriorcalls.com/ https://old.bitchute.com/video/hJW8vB2VDxpt/

#750: On today's episode we're sitting down with Heidi Klum, a German-American model, television host, producer, and businesswoman. At a young age, Heidi disrupted and transformed the modeling industry with her entrepreneurial spirit, redefining the present day industry standards. In this episode, we sit down with Heidi to discuss her career successes, wellness & beauty tips, advice for aspiring models, challenges in the industry, her extravagant Halloween parties, & iconic sex closet.  To connect with Heidi Klum click HERE To connect with Lauryn Bosstick click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE To Watch the Show click HERE For Detailed Show Notes visit TSCPODCAST.COM To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697) This episode is brought to you by The Skinny Confidential Head to the HIM & HER Show ShopMy page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes. This episode is sponsored by AG1 Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/skinny. This episode is sponsored by Caraway Visit Carawayhome.com/himandher to see all of our favorite products and the cookware we use to make cooking easy for even the most amateur home chefs. Plus, take an additional 10% off your next purchase. This episode is sponsored by LMNT Get your free LMNT Sample Pack with any purchase at drinklmnt.com/SKINNY. Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water. This episode is sponsored by Hers Start your free online visit today at forhers.com/TSC for your personalized weight loss treatment options. This episode is sponsored by Hand & Stone Get FREE Aromatherapy with your Introductory Facial, a $10 value, book today at handandstone.com and use code SKINNYFREEAT This episode is sponsored by The Farmer's Dog Get 50% off your first box of fresh, healthy food at TheFarmersDog.com/SKINNY. Plus, you get FREE shipping! Produced by Dear Media

#741: On today's episode Lauryn and Michael are joined by Brent Hruska. Brent is a personal trainer, podcast host, and entrepreneur who has dedicated his life to helping people acheive their health and fitness goals by developing personalized plans for each client. Brent has worked with Lauryn and Michael for 3 years straigh to help them hit their fitness goals. On today's episode Brent and the hosts break down what has worked and not worked when it comes to getting and staying in shape. They discuss what listeners can do to take hold of their own health and fitness journey. This episode covers weight loss, weight management, strength training, how to start in the gym, how to stay motivated, and how to create a plan that works for you.    To connect with Brent Hruska HERE   To connect with Lauryn Bosstick click HERE To connect with Michael Bosstick click HERE Read More on The Skinny Confidential HERE To Watch the Show click HERE For Detailed Show Notes visit TSCPODCAST.COM To Call the Him & Her Hotline call: 1-833-SKINNYS (754-6697) This episode is brought to you by The Skinny Confidential Head to the HIM & HER Show ShopMy page HERE to find all of Michael and Lauryn's favorite products mentioned on their latest episodes.   This episode is sponsored by AG1   It's easy and satisfying to start your journey with AG1. Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/skinny.   This episode is sponsored by Caraway   This deal is exclusive for our listeners, so visit Carawayhome.com/HIMANDHER or use code HIMANDHER at checkout to take an additional 10% off of your next purchase.   This episode is sponsored by Soaak   Visit SOAAK.com/skinny and use code SKINNY at checkout to get your first month free.   This episode is sponsored by Pique   Head over to piquelife.com/skinny to get up to 15% off, and a free cup and frother + free shipping FOR LIFE  when you start on any of my Pique favorites.    This episode is sponsored by Bilt    Earn points by paying rent right now when you go to join bilt.com/skinny.    This episode is sponsored by Hers  Start your free online visit today at forhers.com/TSC.   Produced by Dear Media