Podcasts about united patients group

I had the pleasure of interviewing Janna Champagne, RN, BSN recently to discuss cannabis and spirituality. Janna has been a fantastic TSC Talks Podcast guest several times in the past. I am linking to those podcasts for anyone interested in hearing more from Janna, including her initial “story”, and more detailed information on using cannabis to heal and her work with Autism, leading to developing Autism Safe Haven. Our most recent interview delved into Janna's story and teased out how her lived experience led her to step more fully into her soul's purpose. Janna delivers heartfelt, vulnerable glimpses from her journey thus far in this lifetime. Her lived experience is testimony to the power of continuing to show up, work on herself, and allow herself to surrender and be led by spirit despite some overwhelming odds. A story of personal transformation, hope, and healing. Previous podcasts with Janna: https://tsctalks.com/tsc-talks-guest-jenna-champagne/ Janna's story 12/2019 https://tsctalks.com/tsc-talks-guest-janna-champagne/-on Autism Safe Haven, Autism/Cannabis 12/2020 Links: http://www.integratedholisticcare.com/providers.html https://jannachampagne.com/ https://www.facebook.com/cannanursejanna/ https://www.linkedin.com/in/jannachampagne/ https://www.instagram.com/nursejanna/ From bio: Nurse Janna's introduction to the cannabis industry began as a cannabis patient who happens to be a nurse when she suffered a debilitating immune health collapse in 2012. Janna credits cannabis for helping to reduce her reliance on harmful pharmaceuticals and support her ability to regain her health, including reversal of autoimmune disease, against all odds. Janna is also known for her success in treating her daughter's Autism with cannabis, which was featured as a cover story in a national cannabis industry magazine in 2017. www.integratedholisticcare.com/news Nurse Janna's focus is holistic treatment--natural alternatives to pharmaceuticals including CBD and cannabis therapy. Her work as a cannabis-specialty nurse since 2015 included educating thousands of patients, helping them optimize their cannabis therapy outcomes through an individualized and well-informed approach. Janna has since applied her extensive clinical knowledge to educate medical professionals about cannabis, and help producers create therapeutic quality and targeted cannabis products, with a goal of improving cannabis patient success rates. Janna is also founder of Autism Safe Haven, a 501c3 nonprofit dedicated to improving cannabis-inclusive Autism care resources. Nurse Janna's specialties include: Autism, Inflammatory/Chronic Pain Syndromes, Autoimmune, Neurological, Gastrointestinal, and Mental Health conditions. Janna found that success with cannabis often led to reduced reliance on pharmaceuticals, meanwhile improving quality of life and function. Nurse Janna is a founding member of Cannabis Nurses Network, serving on CNN's Speaker's Bureau, and as leadership. Janna was awarded Leader of Nursing and Outstanding Author for Cannabis Nurses Media in 2019 and nominated/awarded Cannabis Nurses Network 2020 Educator of the Year. Janna offers accredited cannabis nurse education programs, and also serves as a cannabis college professor, teaching graduate student medical practitioners through John Patrick University's Masters of Integrative Medicine Degree Program. Helping producers create optimal cannabis products resulted in one of the CBD product lines winning Top 10 CBD of 2020 designation using Janna's formula recipes (Verdania Fields). Janna also serves as medical advisor and patient advocate for United Patients Group, dedicated to educating consumers with reliable cannabis information. Nurse Janna is a member of the Oregon Cannabis Clinician's Group and volunteers on the Patient Care Subcommittee of the Oregon Cannabis Commission, and the Ryan's Law Oregon Advocacy Team. The flow: 0:00-4:00 Introduction of Janna, bio 4-6:00 Janna gives brief thoughts on her bio 6:25-7:04 Family life, early years, codependency/dysfunction/religiosity family of origin 7:05-8:04 Early experience with spirituality through Reiki 8:05-8:40 Graduated from hs at 17, went right into college, lots of jobs 8:41-55 Age 27 had a daughter and got ill later that year, the start of chronic health issues 8:55-9:39 Age 28 hospitalized, was septic, almost died and had near-death experience that made her want to become a nurse, daughter was only 9 mos old 9:40-10:19 contrast between a nurse that was an advocate vs shamin' blamin' nurse, demonstrated the impact and importance of good care 10:20-11:04 Natural childbirth was a breeze -compared to ongoing stomach issues 11:05-12:14 Root of pain turned out to be perforated appendix leaking! She was septic, peritonitis 12:15-15:00 Ongoing discussion of pain issues..NDE, own mother wasn't sure she'd make it through surgery w/the perforated appendix did not see white lights but was given a choice of whether or not to return. She had thought of her daughter… 15:05-16:35 Starting nursing school, daughter diagnosed w/autism in 10/2004, did a lot of research related to autism, graduated with Bachelors, continued research, worked in intense nursing units, cardiac Cath lab, conscious sedation patients…ended up getting sick 16:35-17:49 Dropped out of nursing school b/c she was so sick, 5 credits short of Masters! Felt suicidal, without a purpose, diagnosed with lupus, on antibiotics, had kidney failure, chronic autoimmune issues 17:50-20:59 Started on Cannabis! Felt some guilt due to upbringing, programming…husband got some white widow, health improved, she couldn't believe it. She started learning everything she could “hungry brain syndrome” 21:00-22:24 a Huge rift in her family of origin over her cannabis use. Catastrophic break, they couldn't accept her use, despite her mom being a nurse. She had a lot of awarenesses about her childhood upbringing 22:25-23:19 Breaking long-standing generational patterns with family, doing a lot of inner work 23:20 Was told by a healer with whom she was working that Cannabis is one of her spirit guides 26:00-27:19 Discussion of deep programming around cannabis and other subjects, are we not allowed to question but just have faith? Religious beliefs question everything 27:20-28:19 She was sent to ultra-conservative HS, almost cultish and you were looked down upon if you hadn't received the gift of speaking in tongues, also discussed PTSD 28:20-29:14 Cannabis is a piece of healing, led her to other tools such as transcendental meditation which was life-altering 29:15-30:09 Special needs moms…. the need to step out of the fire, meditation, walking meditation, being present 30:10-31:04 thoughts the root of all suffering, shifting beliefs, paradigms, we are supported always… 31:05-32:00 Staying in the flow of your life, inspired action, surrendering-the hardest moments have silver linings, stepping into your soul's purpose, higher calling 32:00-32:59 writing a book, questioning medical system with daughter pediatricians clueless, “there's nothing we can do here” 33:00-34:04 Neurodiversity, autism, pain issues, gut issues, goal to help her daughter live her best life, w/the best possibility of reaching full potential 34:05-34:54 had inclination w/Reiki, biomedical approach to daughter's autism, imbalances in the gut, epigenetics/nutrigenomics, cannabis started in 2014 w/puberty crisis 34:55-36:19 Puberty crisis-behaviors become more extreme, pain formulations, communication 36:20-37:59 Narrowly escaped out of home placement, credits cannabis sparing her that additional trauma 38:00-39:14 Start researching cannabis NOW, Jill mentions why its important, cannabis doesn't fix everything, can even just reduce reliance on pharma 39:15-40:05 Are stories are powerful, she published her daughter's story! 40:06-40:49 Endocannabinoid system (ECS) deficiencies lead to chronic illness, autism, etc, many common conditions can be treated by regulating the ECS 40:50-42:09 Cannabis is a gift for our highest good, used for mainstream medicine until 1937. It should be a basic human right…. Jesus may have used cannabis, what would Jesus do? 42:10-43:29 Autism Safe Haven, guided by following cannabis patients needs, cannabis inclusive autism care resources 43:30-44:04 Unity Formulas, for-profit entities, in exchange for contributions…help overcome barriers 44:05-44:54 Building for profits to support nonprofit 44:55-48:34 Cannabis nurses network, Jim Bartel, Ryan's Law, www.cannabisnurseapproved.com can find cannabis nurses 48:35 talk to Jesus, it's a tool, tip of the iceberg, post-traumatic growth, stepping out of our stories, finding purpose in the story, seeing the benefit for others

I had the pleasure of interviewing Janna Champagne, RN, BSN recently to discuss cannabis and spirituality. Janna has been a fantastic TSC Talks Podcast guest several times in the past. I am linking to those podcasts for anyone interested in hearing more from Janna, including her initial “story”, and more detailed information on using cannabis to heal and her work with Autism, leading to developing Autism Safe Haven. Our most recent interview delved into Janna's story and teased out how her lived experience led her to step more fully into her soul's purpose. Janna delivers heartfelt, vulnerable glimpses from her journey thus far in this lifetime. Her lived experience is testimony to the power of continuing to show up, work on herself, and allow herself to surrender and be led by spirit despite some overwhelming odds. A story of personal transformation, hope, and healing. Previous podcasts with Janna:https://tsctalks.com/tsc-talks-guest-jenna-champagne/ Janna's story 12/2019https://tsctalks.com/tsc-talks-guest-janna-champagne/-on Autism Safe Haven, Autism/Cannabis 12/2020Links:http://www.integratedholisticcare.com/providers.html https://jannachampagne.com/ https://www.facebook.com/cannanursejanna/ https://www.linkedin.com/in/jannachampagne/ https://www.instagram.com/nursejanna/ From bio: Nurse Janna's introduction to the cannabis industry began as a cannabis patient who happens to be a nurse when she suffered a debilitating immune health collapse in 2012. Janna credits cannabis for helping to reduce her reliance on harmful pharmaceuticals and support her ability to regain her health, including reversal of autoimmune disease, against all odds. Janna is also known for her success in treating her daughter's Autism with cannabis, which was featured as a cover story in a national cannabis industry magazine in 2017. www.integratedholisticcare.com/newsNurse Janna's focus is holistic treatment--natural alternatives to pharmaceuticals including CBD and cannabis therapy. Her work as a cannabis-specialty nurse since 2015 included educating thousands of patients, helping them optimize their cannabis therapy outcomes through an individualized and well-informed approach. Janna has since applied her extensive clinical knowledge to educate medical professionals about cannabis, and help producers create therapeutic quality and targeted cannabis products, with a goal of improving cannabis patient success rates. Janna is also founder of Autism Safe Haven, a 501c3 nonprofit dedicated to improving cannabis-inclusive Autism care resources.Nurse Janna's specialties include: Autism, Inflammatory/Chronic Pain Syndromes, Autoimmune, Neurological, Gastrointestinal, and Mental Health conditions. Janna found that success with cannabis often led to reduced reliance on pharmaceuticals, meanwhile improving quality of life and function. Nurse Janna is a founding member of Cannabis Nurses Network, serving on CNN's Speaker's Bureau, and as leadership. Janna was awarded Leader of Nursing and Outstanding Author for Cannabis Nurses Media in 2019 and nominated/awarded Cannabis Nurses Network 2020 Educator of the Year. Janna offers accredited cannabis nurse education programs, and also serves as a cannabis college professor, teaching graduate student medical practitioners through John Patrick University's Masters of Integrative Medicine Degree Program. Helping producers create optimal cannabis products resulted in one of the CBD product lines winning Top 10 CBD of 2020 designation using Janna's formula recipes (Verdania Fields). Janna also serves as medical advisor and patient advocate for United Patients Group, dedicated to educating consumers with reliable cannabis information. Nurse Janna is a member of the Oregon Cannabis Clinician's Group and volunteers on the Patient Care Subcommittee of the Oregon Cannabis Commission, and the Ryan's Law Oregon Advocacy Team. The flow:0:00-4:00 Introduction of Janna, bio4-6:00 Janna gives brief thoughts on her bio6:25-7:04 Family life, early years, codependency/dysfunction/religiosity family of origin7:05-8:04 Early experience with spirituality through Reiki8:05-8:40 Graduated from hs at 17, went right into college, lots of jobs8:41-55 Age 27 had a daughter and got ill later that year, the start of chronic health issues8:55-9:39 Age 28 hospitalized, was septic, almost died and had near-death experience that made her want to become a nurse, daughter was only 9 mos old9:40-10:19 contrast between a nurse that was an advocate vs shamin' blamin' nurse, demonstrated the impact and importance of good care10:20-11:04 Natural childbirth was a breeze -compared to ongoing stomach issues11:05-12:14 Root of pain turned out to be perforated appendix leaking! She was septic, peritonitis12:15-15:00 Ongoing discussion of pain issues..NDE, own mother wasn't sure she'd make it through surgery w/the perforated appendix did not see white lights but was given a choice of whether or not to return. She had thought of her daughter…15:05-16:35 Starting nursing school, daughter diagnosed w/autism in 10/2004, did a lot of research related to autism, graduated with Bachelors, continued research, worked in intense nursing units, cardiac Cath lab, conscious sedation patients…ended up getting sick16:35-17:49 Dropped out of nursing school b/c she was so sick, 5 credits short of Masters! Felt suicidal, without a purpose, diagnosed with lupus, on antibiotics, had kidney failure, chronic autoimmune issues17:50-20:59 Started on Cannabis! Felt some guilt due to upbringing, programming…husband got some white widow, health improved, she couldn't believe it. She started learning everything she could “hungry brain syndrome”21:00-22:24 a Huge rift in her family of origin over her cannabis use. Catastrophic break, they couldn't accept her use, despite her mom being a nurse. She had a lot of awarenesses about her childhood upbringing 22:25-23:19 Breaking long-standing generational patterns with family, doing a lot of inner work23:20 Was told by a healer with whom she was working that Cannabis is one of her spirit guides26:00-27:19 Discussion of deep programming around cannabis and other subjects, are we not allowed to question but just have faith? Religious beliefs question everything27:20-28:19 She was sent to ultra-conservative HS, almost cultish and you were looked down upon if you hadn't received the gift of speaking in tongues, also discussed PTSD28:20-29:14 Cannabis is a piece of healing, led her to other tools such as transcendental meditation which was life-altering 29:15-30:09 Special needs moms…. the need to step out of the fire, meditation, walking meditation, being present30:10-31:04 thoughts the root of all suffering, shifting beliefs, paradigms, we are supported always…31:05-32:00 Staying in the flow of your life, inspired action, surrendering-the hardest moments have silver linings, stepping into your soul's purpose, higher calling32:00-32:59 writing a book, questioning medical system with daughter pediatricians clueless, “there's nothing we can do here”33:00-34:04 Neurodiversity, autism, pain issues, gut issues, goal to help her daughter live her best life, w/the best possibility of reaching full potential34:05-34:54 had inclination w/Reiki, biomedical approach to daughter's autism, imbalances in the gut, epigenetics/nutrigenomics, cannabis started in 2014 w/puberty crisis34:55-36:19 Puberty crisis-behaviors become more extreme, pain formulations, communication36:20-37:59 Narrowly escaped out of home placement, credits cannabis sparing her that additional trauma38:00-39:14 Start researching cannabis NOW, Jill mentions why its important, cannabis doesn't fix everything, can even just reduce reliance on pharma39:15-40:05 Are stories are powerful, she published her daughter's story!40:06-40:49 Endocannabinoid system (ECS) deficiencies lead to chronic illness, autism, etc, many common conditions can be treated by regulating the ECS40:50-42:09 Cannabis is a gift for our highest good, used for mainstream medicine until 1937. It should be a basic human right…. Jesus may have used cannabis, what would Jesus do?42:10-43:29 Autism Safe Haven, guided by following cannabis patients needs, cannabis inclusive autism care resources43:30-44:04 Unity Formulas, for-profit entities, in exchange for contributions…help overcome barriers44:05-44:54 Building for profits to support nonprofit44:55-48:34 Cannabis nurses network, Jim Bartel, Ryan's Law, www.cannabisnurseapproved.com can find cannabis nurses48:35 talk to Jesus, it's a tool, tip of the iceberg, post-traumatic growth, stepping out of our stories, finding purpose in the story, seeing the benefit for others

For the past century cannabis has been demonized. Prior to that, it was revered for thousands of years as one of the most powerful plants on the planet.  On this episode we get into all things cannabis with John Malanca, the founder and CEO of United Patients Group, an unparalleled resource and trusted leader in medical cannabis for physicians, pharmacists, patients, their families, and governments, both nationally and globally.  John has been the go-to expert and trusted professional in education and information in medical cannabis and the health and wellness sector since 2011. We chat about all things cannabis as well as: the endocannabinoid system John's life experience that prompted him to create UPG the different cannabinoids  why it's not a one size fit all government issues  success stories what to look for in choosing a cannabis product different ways to consume cannabis hemp CBD John's experience going plant-based  infrared saunas benefits of sweating microdosing plant based medicines the v word and some other juicy topics United Patients Group UPG IG: @unitedpatientsgroup The Refined Hippie  My IG: @therefinedhippie

John Malanca was inspired to start United Patients Group in 2011 after a totally unexpected episode when his father-in-law Stan was diagnosed with Stage 4 lung cancer along with a brain tumor on his brain stem. The situation seemed hopeless, seeing their father going from being a seemingly healthy 77-year-old one day, to being given a mere two weeks to live the next. “When you're diagnosed,” says John, recalling those moments of desperation, “you'll try anything.” That “anything”, as fate would have it, was cannabis. They started by giving Stan THC capsules infused with coconut oil in order to get him to start eating again. It worked. A day later, he was back at work on a computer. Nine months after the diagnosis, John's family got an email that simply stated “no evidence of recurrent disease.” That was in 2011. Today, Stan is alive and well. Listen in as John shares the exciting journey that emerged out of that harrowing experience. He describes the many benefits of the cannabis plant and, by extension, naturopathic modalities, and how these can help bring the body back to homeostasis.   Follow United Patients Group @unitedpatientsgroup Follow Chase @chase_chewning   Episode resources: Save 15% on CBN tinctures from Cured Nutrition with code EVERFORWARD at http://bit.ly/2RmXcja Learn more at https://chasechewning.com/podcasts/episode/490 

Dr. Leah Johnson (known to the cannabis community as Dr. Leah "The Holistic Healer") is a trained Clinical Cannabis Pharmacist and the owner and CEO of Alchemist Consulting. She is also an accomplished, highly driven clinical Long-Term Care & Rehabilitation pharmacist, with primary focus in pain, mental health (depression, anxiety, Insomnia, etc.) and sexual health medication management.She also holds 3 patents (under the name: Leah Haibi) for natural herbal remedy tinctures, which she helped develop as the Head of Research & Development for an herbal supplement company.Dr. Leah believes that complete physical & mental health and well-being can be influenced by the utilization of cannabis, as well as other herbal remedies and supplements, in conjunction with pharmaceutical medications. She believes that most patients are given too many and inappropriate prescription medications, while not being given the knowledge for utilizing effective herbals and supplements to reduce pill burden. She also believes that many patients are unable to get full relief of their ailments due to the missing components in their medication regimens.In an effort to improve the overall health and well-being of patients, Dr. Leah works with patients and their healthcare providers, from all over the country, to reduce the amount of medications taken, alter timing and dosing of medications to improve effectiveness, and identify medications which could be causing issues.She also works with cannabis companies to advise them on dosing, safety, interactions, and how to better help their customers see health improvements with the use of their products. She also holds a Doctorate degree in Pharmacy from the Massachusetts College of Pharmacy and Health Sciences.Visit us at: https://www.unitedpatientsgroup.comFollow us on Twitter: https://www.twitter.com/upatientsgroupFacebook: https://www.facebook.com/UnitedPatientsGroup/

There are few voices more recognisable across the cannabis-curious world than John Malanca's. With his wife and love of his life Corinne, John fronted the global docuseries, 'The Sacred Plant' that's been seen by over 600,000 people worldwide.Their introduction to the healing powers of the cannabis plant came when Corinne's dad, given just months to live with terminal cancer, made a full recovery after he began taking cannabis oil.The couple went on to start The United Patients Group, a go-to source for medical cannabis education for patients, care-givers and health professionals alike.Tragically in 2017, Corinne herself was diagnosed with pancreatic cancer, and despite trying everything medicine had to offer, including cannabis, she sadly passed away just 4 months later. Left without his life partner, John threw himself into the second series of the Sacred Plant, but has since stepped away and is now back concentrating on the United Patients Group once more.John speaks honestly and openly about his struggles to deal with the grief following Corinne's death, and how continuing the work they started together has helped him find meaning in the darkest times. John is happy to hear from anyone going through or supporting someone with terminal illness, particularly pancreatic cancer, and he can be contacted through the United Patients Group website or info@UnitedPatientsGroup.com. Support the show (https://www.paypal.com/paypalme/marybiles71)

In this episode, we talk with John Malanca about Nature's most healing plant! We tackle topics like, what is cannabis, how it used medically, the difference between THC and CBD, and much more! Fact: Most cancer patients do not die from cancer, but malnutrition.  John’s Introduction into Medical Cannabis  In 2011, father-in-law was battling stage 4 lung cancer, couldn’t eat, and was on oxygen 24/7.  Doctor gave him two weeks to live.  Started using a coconut oil capsule infused with raw and heated cannabis.  Within 24 hours he was eating, by day 8 he was walking around the house.  At the 3 month mark, switched to a full extract cannabis oil - administering a minute amount in the evening.  Within 6 months he was walking, driving, and Hospice fired him as a patient!  By the 9th month he had the first scan to show, “No evidence of recurrent disease."  After 17 lung and brain scans showing no evidence of recurrent disease! He is still healthy and happy today - 8 years later!    United Patients Group  Founded by John and Corrine Malanca to fill the information void surrounding medical cannabis.  Don't sell products - strictly education and information.  Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis.  All courses are CME approved continuing medical education.    What is cannabis?  Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae.   Also known as Hemp if less than .03% THC in the composition of the plant  Three species may be recognized:   Cannabis Sativa – formulations that include more uplifting, “day time” feelings  Cannabis Indica - formulations that include more sedative and relaxing effects, including pain reduction   Cannabis Ruderalis - (not discussed in the interview) naturally low concentrations of THC occurring, more research is being done on this variation of the species   Cannabis Hybrid - formulations that are mixes of Sativa and Indica based plants made from crossbreeding    There are currently 483 known compounds in the plant.  The main psychoactive part of cannabis is tetrahydrocannabinol (THC). Although this is the main psychoactive components of the plant, it is also one of the main cannabinoids needed and used in medical treatments when Cannabis is on the protocol.   Contains at least 113 cannabinoids     Two Known Subtypes of Cannabinoid Receptors  First discovered in the 1980s. Located throughout the body. Part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and more that have since been researched. These receptors are all over our body, head to toe.  The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys.   These receptors are thought to be one of the most widely expressed Gαi protein-coupled receptors in the brain  The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells.  These receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells.   They also have a function in keratinocytes.   They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.    What are Cannabinoids?  A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.   113 cannabinoids have been isolated from the Cannabis plant.  Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes as well as by the other cannabinoids.  This interaction would lead to the entourage effect.    Medical Uses  Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, as well as terpenes, to treat disease or improve symptoms relief.   reduce nausea and vomiting during chemotherapy  improve appetite in people with HIV/AIDS or cancer  treat chronic pain and muscle spasms (MS and other nerve related pain)  lessens tremors in Parkinson’s Disease  control seizures  reduce pain of cluster headaches in minutes  cannabinoids are under preliminary research for their potential to affect stroke  THC has been shown to kill cancer cells  CBD has been shown to stop cancer cells and prevent the spread  Many more!    Delivery Systems - Ways to Consume Medical Cannabis  Sublingual absorption  Topical  Vaporization  Suppositories  Transdermal patches  Edibles      Interesting Statistics    This statistic presents the percentage of U.S. adults who would recommend medical cannabis to their friends as of January 2017. It was found that 62 percent of respondents aged between 18 and 34 years were likely to recommend cannabis.      This statistic displays the annual number of daily doses of prescribed drugs per physician in U.S. states with and without medical cannabis law, as of 2016. According to the data, physicians in states without medical cannabis laws prescribed about 95,672 daily doses of medication annually. Compared to that, the number was significantly lower in states which had a medical cannabis law.      This graph shows the number of legal medical marijuana patients by U.S. state, per 1,000 state residents, as of May 17, 2018. The state of Colorado had the highest rate of legal medical marijuana patients per 1,000 state residents with 15.86 patients    Region: United States  Survey time period: as of May 17, 2018  Supplementary notes...  No data available for: North Dakota, Ohio, West Virginia.   * Arkansas has started issuing medical marijuana registry ID cards, but marijuana is not yet available in the state.   ** California had 5,848 registered patients in Fiscal Year 2017/2018, but registration is voluntary and most patients are not registered. We made an estimate using the per capita number of patients in Arizona because of geographical proximity. The Marijuana Policy Project's (MPP) Feb. 2018 estimate for California, 1,256,550, used Maine's per capita number of patients.   *** In presenting the number of medical marijuana registration cards printed, Maine's medical marijuana program website states, "This number is not an accurate reflection of the number of patients as it contains all certifications printed, including misprints, reissue of lost certifications and other anomalies."   **** Washington listed 32,123 recognition cards created as of May 16, 2018, but registration isn't required to be a medical marijuana patient except for patients under 18. As a result, we created an estimate based on the per capita patient numbers in Oregon.            Deeper Dive Resources    John Malanca:  https://www.linkedin.com/in/john-malanca-7807956b  https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/    United Patients Group:  https://unitedpatientsgroup.com/  https://www.facebook.com/UnitedPatientsGroup/      Cannabis:  https://en.wikipedia.org/wiki/Cannabis    Indica vs Sativa:  https://www.leafly.com/news/cannabis-101/sativa-indica-and-hybrid-differences-between-cannabis-types    Ruderalis:  https://www.leafly.com/news/cannabis-101/what-is-cannabis-ruderalis    Cannabinoids:  https://en.wikipedia.org/wiki/Cannabinoid    Entourage Effect:  https://en.wikipedia.org/wiki/Entourage_effect    Side by Side Image of Cannabis and Lyrica:  https://unitedpatientsgroup.com/blog/2014/06/30/fibromyalgia-big-pharma-vs-medical-cannabis    Laws By State:  https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State    Studies in 2018:  Cannabis Is Safe and Effective at Treating Pain in the Elderly  CBD Protects Against the Damaging Effects of Iron in Aging Brain Diseases  A Case for Balanced THC and CBD in Colorectal Cancer Prevention  CBD Protects Against Endometrial Cancer by Activating TRPV1 Receptors  THC Enhances the Pain-Relieving Effects of Opioids in Double-Blinded, Placebo-Controlled Study  THC Boosts the Efficacy of a Traditional Neuropathic Pain Medication  CBD Blocks Toxin’s Ability to Promote Schizophrenia-like Symptoms  Cannabis Protects Against Alcohol’s Damaging Effects on the Stomach  A Balanced Cannabis Approach May Treat Spasticity in ALS  Cannabis Smoke Improves Working Memory in Underperformers  The Entourage Effect in Rodent-Model Breast Cancer  A Deeper Understanding of Cannabis’s Anti-Nausea Effects  A Shift in Cannabis & Schizophrenia Theory  Clinical Trial Finds Benefits of CBD in Autism  A Novel Target for Low-Dose CBD Is Identified  CBD Treats Brain Changes Caused by Regular Cannabis Use  Transdermal CBD for the Treatment of Non-Opioid Addictions  Plant-Derived Cannabinoids Improve the Efficacy of Cancer Treatment  CBD’s Fast-Acting, Long-Lasting Antidepressant Effects in Rodents  Cannabis-Based Pharmaceutical Improves Symptoms of Multiple Sclerosis    

In this episode, we talk with John Malanca about Nature's most healing plant! We tackle topics like, what is cannabis, how it used medically, the difference between THC and CBD, and much more! Fact: Most cancer patients do not die from cancer, but malnutrition.  John’s Introduction into Medical Cannabis  In 2011, father-in-law was battling stage 4 lung cancer, couldn’t eat, and was on oxygen 24/7.  Doctor gave him two weeks to live.  Started using a coconut oil capsule infused with raw and heated cannabis.  Within 24 hours he was eating, by day 8 he was walking around the house.  At the 3 month mark, switched to a full extract cannabis oil - administering a minute amount in the evening.  Within 6 months he was walking, driving, and Hospice fired him as a patient!  By the 9th month he had the first scan to show, “No evidence of recurrent disease."  After 17 lung and brain scans showing no evidence of recurrent disease! He is still healthy and happy today - 8 years later!    United Patients Group  Founded by John and Corrine Malanca to fill the information void surrounding medical cannabis.  Don't sell products - strictly education and information.  Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis.  All courses are CME approved continuing medical education.    What is cannabis?  Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae.   Also known as Hemp if less than .03% THC in the composition of the plant  Three species may be recognized:   Cannabis Sativa – formulations that include more uplifting, “day time” feelings  Cannabis Indica - formulations that include more sedative and relaxing effects, including pain reduction   Cannabis Ruderalis - (not discussed in the interview) naturally low concentrations of THC occurring, more research is being done on this variation of the species   Cannabis Hybrid - formulations that are mixes of Sativa and Indica based plants made from crossbreeding    There are currently 483 known compounds in the plant.  The main psychoactive part of cannabis is tetrahydrocannabinol (THC). Although this is the main psychoactive components of the plant, it is also one of the main cannabinoids needed and used in medical treatments when Cannabis is on the protocol.   Contains at least 113 cannabinoids     Two Known Subtypes of Cannabinoid Receptors  First discovered in the 1980s. Located throughout the body. Part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and more that have since been researched. These receptors are all over our body, head to toe.  The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys.   These receptors are thought to be one of the most widely expressed Gαi protein-coupled receptors in the brain  The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells.  These receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells.   They also have a function in keratinocytes.   They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.    What are Cannabinoids?  A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.   113 cannabinoids have been isolated from the Cannabis plant.  Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes as well as by the other cannabinoids.  This interaction would lead to the entourage effect.    Medical Uses  Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, as well as terpenes, to treat disease or improve symptoms relief.   reduce nausea and vomiting during chemotherapy  improve appetite in people with HIV/AIDS or cancer  treat chronic pain and muscle spasms (MS and other nerve related pain)  lessens tremors in Parkinson’s Disease  control seizures  reduce pain of cluster headaches in minutes  cannabinoids are under preliminary research for their potential to affect stroke  THC has been shown to kill cancer cells  CBD has been shown to stop cancer cells and prevent the spread  Many more!    Delivery Systems - Ways to Consume Medical Cannabis  Sublingual absorption  Topical  Vaporization  Suppositories  Transdermal patches  Edibles      Interesting Statistics    This statistic presents the percentage of U.S. adults who would recommend medical cannabis to their friends as of January 2017. It was found that 62 percent of respondents aged between 18 and 34 years were likely to recommend cannabis.      This statistic displays the annual number of daily doses of prescribed drugs per physician in U.S. states with and without medical cannabis law, as of 2016. According to the data, physicians in states without medical cannabis laws prescribed about 95,672 daily doses of medication annually. Compared to that, the number was significantly lower in states which had a medical cannabis law.      This graph shows the number of legal medical marijuana patients by U.S. state, per 1,000 state residents, as of May 17, 2018. The state of Colorado had the highest rate of legal medical marijuana patients per 1,000 state residents with 15.86 patients    Region: United States  Survey time period: as of May 17, 2018  Supplementary notes...  No data available for: North Dakota, Ohio, West Virginia.   * Arkansas has started issuing medical marijuana registry ID cards, but marijuana is not yet available in the state.   ** California had 5,848 registered patients in Fiscal Year 2017/2018, but registration is voluntary and most patients are not registered. We made an estimate using the per capita number of patients in Arizona because of geographical proximity. The Marijuana Policy Project's (MPP) Feb. 2018 estimate for California, 1,256,550, used Maine's per capita number of patients.   *** In presenting the number of medical marijuana registration cards printed, Maine's medical marijuana program website states, "This number is not an accurate reflection of the number of patients as it contains all certifications printed, including misprints, reissue of lost certifications and other anomalies."   **** Washington listed 32,123 recognition cards created as of May 16, 2018, but registration isn't required to be a medical marijuana patient except for patients under 18. As a result, we created an estimate based on the per capita patient numbers in Oregon.            Deeper Dive Resources    John Malanca:  https://www.linkedin.com/in/john-malanca-7807956b  https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/    United Patients Group:  https://unitedpatientsgroup.com/  https://www.facebook.com/UnitedPatientsGroup/      Cannabis:  https://en.wikipedia.org/wiki/Cannabis    Indica vs Sativa:  https://www.leafly.com/news/cannabis-101/sativa-indica-and-hybrid-differences-between-cannabis-types    Ruderalis:  https://www.leafly.com/news/cannabis-101/what-is-cannabis-ruderalis    Cannabinoids:  https://en.wikipedia.org/wiki/Cannabinoid    Entourage Effect:  https://en.wikipedia.org/wiki/Entourage_effect    Side by Side Image of Cannabis and Lyrica:  https://unitedpatientsgroup.com/blog/2014/06/30/fibromyalgia-big-pharma-vs-medical-cannabis    Laws By State:  https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State    Studies in 2018:  Cannabis Is Safe and Effective at Treating Pain in the Elderly  CBD Protects Against the Damaging Effects of Iron in Aging Brain Diseases  A Case for Balanced THC and CBD in Colorectal Cancer Prevention  CBD Protects Against Endometrial Cancer by Activating TRPV1 Receptors  THC Enhances the Pain-Relieving Effects of Opioids in Double-Blinded, Placebo-Controlled Study  THC Boosts the Efficacy of a Traditional Neuropathic Pain Medication  CBD Blocks Toxin’s Ability to Promote Schizophrenia-like Symptoms  Cannabis Protects Against Alcohol’s Damaging Effects on the Stomach  A Balanced Cannabis Approach May Treat Spasticity in ALS  Cannabis Smoke Improves Working Memory in Underperformers  The Entourage Effect in Rodent-Model Breast Cancer  A Deeper Understanding of Cannabis’s Anti-Nausea Effects  A Shift in Cannabis & Schizophrenia Theory  Clinical Trial Finds Benefits of CBD in Autism  A Novel Target for Low-Dose CBD Is Identified  CBD Treats Brain Changes Caused by Regular Cannabis Use  Transdermal CBD for the Treatment of Non-Opioid Addictions  Plant-Derived Cannabinoids Improve the Efficacy of Cancer Treatment  CBD’s Fast-Acting, Long-Lasting Antidepressant Effects in Rodents  Cannabis-Based Pharmaceutical Improves Symptoms of Multiple Sclerosis    

Cannabis. My Life, My Motivation. With Karyemaitre Aliffe, MDJohn Malanca interviews Dr. Karyemaitre Aliffe, who earned a BA from Harvard University in Organic & Medicinal Chemistry, and MD with Distinguished Honors (magna cum laude), from Stanford University School of Medicine in an MD-PhD Training Program in Cancer Biology, Departments of Molecular Pharmacology, Chemical and Systems Biology. His postgraduate clinical training, also from Stanford, is in Anesthesiology, Intensive Care and Pain Management.John and Karyemaitre discuss his current work which covers many potential new applications of Hemp•Cannabis, so they have plenty to discuss! Dr. Aliffe believes the key issue is the clarification that Hemp•Cannabis does not produce THC when processed fresh at low temperatures. This misconception can be misleading to patients and degrade the definition of Hemp vs full spectrum cannabis, various chemovars, terpene profiles and cause continued confusion.Dr. Aliffe, now a Cannabis expert, is devoting himself to his work, "A Fresh Look at Hemp•Cannabis-Clarifying misconceptions about one of the greatest medicines in Nature's Pharmacy."An engaging guest, United Patients Group followers will enjoy this interview while learning the power and importance of the acid form of hemp, which will assist patients in promoting wellness and enhancing health!

Description: On this special episode of the Know Your Dose Podcast, Derek has a conversation with John Malanca, founder and CEO of United Patients Group. United Patients Group is the leading source for patient information on cannabis and CBD treatments, with years of industry experience and countless accolades from educational and medical institutions. Make sure to tune in for an intriguing conversation on John’s background, experience, and outlook on the cannabis industry that you won’t want to miss!   Show Notes (People / Products / Mentions): John Malanca Returns To Where It All Began - United Patients Group Be Informed. Be Well. Podcast With John Malanca In Loving Memory of Corinne Malanca Baked Bros - Cannabis and Breast Cancer Baked Bros - Cannabis and Wellness: Balancing Your Endocannabinoid System With Cannabis, Diet, and Exercise LEAVE A REVIEW FOR A FREE SHIRT Connect With Us: Website: https://knowyourdosepodcast.com Instagram: https://instagram.com/knowyourdosepodcast  Facebook: https://facebook.com/bakedbrosthc/  Company: https://bakedbros.com  Text "JOIN KYD" to (480) 680-8792 for specials, new product updates, and more!

#5 On this episode I talk with John Malanca, the CEO and founder of United Patients Group, and the host of The Sacred Plant, a docu-series on the power of medical cannabis, treating a host of diseases with the plant and common myths around medical cannabis. Join us as the conversation takes a turn to one of the most tender and heart opening moments as we discuss facing death, and navigating life through the cycles of grief.

In this week’s episode we dive deeper into understanding medical cannabis. Does it really cure what ails you or is this all smoke and mirrors?   Fact: Tetrahydrocannabinolic acid (THCA), the raw acid form of THC, is the most abundant non-psychoactive cannabinoid found in cannabis. What is the endocannabinoid system (ECS)? a biological system composed of endocannabinoids first discovered in the late 1980’s promotes homeostasis at every level of biological life all vertebrates are known to have receptors have been found all over the body and interact with the major systems found within our body.   ECS is Made Up of 3 Parts Endocannabinoids Receptors in the nervous system and around the body that endocannabinoids and cannabinoids bond with Enzymes that help break down endocannabinoids and cannabinoids   Functions of the Endocannabinoid System Research shows it is an overall body modulating system, doing its best to get our body to balance and keep it there. Memory Appetite Digestion Mood Inflammation Energy Storage and Metabolism Stress Response Immune Function Female Reproduction Autonomic Nervous System Analgesia Thermoregulation Sleep Physical Exercise May play a dual role on the regulation of tumor generation and progression   Receptors Two Known receptors in our body that interact either with internal or external cannabinoids are the CB1 and CB2. Cannabinoid - The CB1 receptor is expressed mainly in the brain and nerves of the spinal cord (central nervous system or "CNS"), but also in the lungs, liver and kidneys. Endocannabinoid - The CB2 receptor is expressed mainly in the peripheral nervous system (nerves in your extremities), the digestive system, and specialized cells in the immune system   Risks of Self Dosing with Recreational Cannabis Not seeking recommendation on dosing from a medical professional may be problematic to the individual. Drug to drug interactions Self-misdiagnosis Correct dosage   Cannabis and Inflammation THCA tinctures infused with coconut oil or grapeseed oil THCA is non-psychoactive until introduced to heat Very effective in maintaining a healthy inflammation response   Cannabis and Sleep D. Anderson has said, "Less than six hours, and more than nine hours of sleep is bad." Often poor sleep is the root cause of issues like depression and anxiety Indica strain of cannabis plant is good for sleep - take one hour before bed L-Tryptophan is also a good option to aid sleep   Ratios You will hear 2:1 ratio, 4:1 ratio, 8:1 ratio, 16:1 ratio. This can be CBD:THC or THC:CBD. Always ask what that first number is. Don't be afraid to ask the question, “what is the first number?   Considerations When Using Medical Cannabis Avoid synthetic versions due to side effects Be educated before talking to your Doctor Use reputable dispensaries who create clean cannabis and provide test results May be used as preventative wellness medicine   The Sacred Plant John Malanca is host and advocate, along side Founder Manny Goldman Provide education and insights from the Patient, Physician, Caregivers, Researchers, and more perspective and experiences with Cannabis as medicine Helping break down the stigmas, understand the research, and using this information to continue advocacy   United Patients Group Founded by John and Corinne Malanca to fill the information void surrounding medical cannabis. Don't sell products - patient advocacy - strictly education and information. Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis. All courses are CME (continuing medical education) approved by the American Medical Association.     Deeper Dive Resources   John Malanca: https://www.linkedin.com/in/john-malanca-7807956b https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/   United Patients Group: https://unitedpatientsgroup.com/ https://www.facebook.com/UnitedPatientsGroup/   The Sacred Plant: http://thesacredplant.online/t?orid=614242&opid=796&sid=D18L1_podcast https://www.facebook.com/oursacredplant/   The History of Cannabis as a Medicine: http://www.scielo.br/scielo.php?pid=S1516-44462006000200015&script=sci_arttext&tlng=pt   Endocannabinoid System: https://en.wikipedia.org/wiki/Endocannabinoid_system   Cannabinoids: https://en.wikipedia.org/wiki/Cannabinoid   Cash Hyde Foundation: http://www.cashhydefoundation.org/cashys-story   GW Pharmaceuticals: https://www.gwpharm.com/   Hemp: https://en.wikipedia.org/wiki/Hemp   Laws By State: https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State     Studies: Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes - Medicine continues to struggle in its approaches to numerous common subjective pain syndromes that lack objective signs and remain treatment resistant. Foremost among these are migraine, fibromyalgia, and irritable bowel syndrome, disorders that may overlap in their affected populations and whose sufferers have all endured the stigma of a psychosomatic label, as well as the failure of endless pharmacotherapeutic interventions with substandard benefit. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576607/     The role of the endocannabinoid system in the regulation of endocrine function and in the control of energy balance in humans - The endocannabinoid system has been recently recognized as an important modulatory system in the function of brain, endocrine, and immune tissues. It appears to play a very important regulatory role in the secretion of hormones related to reproductive functions and response to stress. https://www.ncbi.nlm.nih.gov/pubmed/17369778     Endocannabinoid system acts as a regulator of immune homeostasis in the gut - Study unveils a role for the endocannabinoid system in maintaining immune homeostasis in the gut/pancreas and reveals a conversation between the nervous and immune systems using distinct receptors. https://www.pnas.org/content/early/2017/04/18/1612177114.long     The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities - Recent studies have intriguingly suggested the existence of a functional ECS in the skin and implicated it in various biological processes (e.g. proliferation, growth, differentiation, apoptosis and cytokine, mediator or hormone production of various cell types of the skin and appendages, such as the hair follicle and sebaceous gland). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/     Regulation of circulating endocannabinoids associated with cancer and metastases in mice and humans - The endocannabinoid system was subject to cancer-associated regulations to an extent that led to measurable changes in circulating endocannabinoid levels, emphasizing the importance of the endocannabinoid system in the pathophysiology of cancer. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278301/     Endocannabinoid and ceramide levels are altered in patients with colorectal cancer - Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of human colorectal cancer tissues and adjacent non-tumor tissues. https://www.ncbi.nlm.nih.gov/pubmed/25975960     Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa - Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. https://academic.oup.com/ajcn/article/101/2/262/4494381     Gastric acid inhibitory and gastric protective effects of Cannabis and cannabinoids - Cannabis and/or cannabinoids protect the gastric mucosa against noxious challenge with non-steroidal anti-inflammatory drugs, ethanol as well as against stress-induced mucosal damage. Cannabis/cannabinoids might protect the gastric mucosa by virtue of its antisecretory, antioxidant, anti-inflammatory, and vasodilator properties. https://www.sciencedirect.com/science/article/pii/S1995764516300712     The use of cannabinoids as anticancer agents - In conclusion there exist solid scientific evidences supporting that cannabinoids exhibit a remarkable anticancer activity in preclinical models of cancer. Since these agents also show an acceptable safety profile, clinical studies aimed at testing them as single agents or in combinational therapies are urgently needed. Results from these studies are essential to clarify whether cannabinoids (and specifically cannabinoid-based medicines) could be helpful in the fight of cancer. https://www.sciencedirect.com/science/article/pii/S0278584615001190

In this week’s episode we dive deeper into understanding medical cannabis. Does it really cure what ails you or is this all smoke and mirrors?   Fact: Tetrahydrocannabinolic acid (THCA), the raw acid form of THC, is the most abundant non-psychoactive cannabinoid found in cannabis. What is the endocannabinoid system (ECS)? a biological system composed of endocannabinoids first discovered in the late 1980’s promotes homeostasis at every level of biological life all vertebrates are known to have receptors have been found all over the body and interact with the major systems found within our body.   ECS is Made Up of 3 Parts Endocannabinoids Receptors in the nervous system and around the body that endocannabinoids and cannabinoids bond with Enzymes that help break down endocannabinoids and cannabinoids   Functions of the Endocannabinoid System Research shows it is an overall body modulating system, doing its best to get our body to balance and keep it there. Memory Appetite Digestion Mood Inflammation Energy Storage and Metabolism Stress Response Immune Function Female Reproduction Autonomic Nervous System Analgesia Thermoregulation Sleep Physical Exercise May play a dual role on the regulation of tumor generation and progression   Receptors Two Known receptors in our body that interact either with internal or external cannabinoids are the CB1 and CB2. Cannabinoid - The CB1 receptor is expressed mainly in the brain and nerves of the spinal cord (central nervous system or "CNS"), but also in the lungs, liver and kidneys. Endocannabinoid - The CB2 receptor is expressed mainly in the peripheral nervous system (nerves in your extremities), the digestive system, and specialized cells in the immune system   Risks of Self Dosing with Recreational Cannabis Not seeking recommendation on dosing from a medical professional may be problematic to the individual. Drug to drug interactions Self-misdiagnosis Correct dosage   Cannabis and Inflammation THCA tinctures infused with coconut oil or grapeseed oil THCA is non-psychoactive until introduced to heat Very effective in maintaining a healthy inflammation response   Cannabis and Sleep D. Anderson has said, "Less than six hours, and more than nine hours of sleep is bad." Often poor sleep is the root cause of issues like depression and anxiety Indica strain of cannabis plant is good for sleep - take one hour before bed L-Tryptophan is also a good option to aid sleep   Ratios You will hear 2:1 ratio, 4:1 ratio, 8:1 ratio, 16:1 ratio. This can be CBD:THC or THC:CBD. Always ask what that first number is. Don't be afraid to ask the question, “what is the first number?   Considerations When Using Medical Cannabis Avoid synthetic versions due to side effects Be educated before talking to your Doctor Use reputable dispensaries who create clean cannabis and provide test results May be used as preventative wellness medicine   The Sacred Plant John Malanca is host and advocate, along side Founder Manny Goldman Provide education and insights from the Patient, Physician, Caregivers, Researchers, and more perspective and experiences with Cannabis as medicine Helping break down the stigmas, understand the research, and using this information to continue advocacy   United Patients Group Founded by John and Corinne Malanca to fill the information void surrounding medical cannabis. Don't sell products - patient advocacy - strictly education and information. Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis. All courses are CME (continuing medical education) approved by the American Medical Association.     Deeper Dive Resources   John Malanca: https://www.linkedin.com/in/john-malanca-7807956b https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/   United Patients Group: https://unitedpatientsgroup.com/ https://www.facebook.com/UnitedPatientsGroup/   The Sacred Plant: http://thesacredplant.online/t?orid=614242&opid=796&sid=D18L1_podcast https://www.facebook.com/oursacredplant/   The History of Cannabis as a Medicine: http://www.scielo.br/scielo.php?pid=S1516-44462006000200015&script=sci_arttext&tlng=pt   Endocannabinoid System: https://en.wikipedia.org/wiki/Endocannabinoid_system   Cannabinoids: https://en.wikipedia.org/wiki/Cannabinoid   Cash Hyde Foundation: http://www.cashhydefoundation.org/cashys-story   GW Pharmaceuticals: https://www.gwpharm.com/   Hemp: https://en.wikipedia.org/wiki/Hemp   Laws By State: https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State     Studies: Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes - Medicine continues to struggle in its approaches to numerous common subjective pain syndromes that lack objective signs and remain treatment resistant. Foremost among these are migraine, fibromyalgia, and irritable bowel syndrome, disorders that may overlap in their affected populations and whose sufferers have all endured the stigma of a psychosomatic label, as well as the failure of endless pharmacotherapeutic interventions with substandard benefit. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576607/     The role of the endocannabinoid system in the regulation of endocrine function and in the control of energy balance in humans - The endocannabinoid system has been recently recognized as an important modulatory system in the function of brain, endocrine, and immune tissues. It appears to play a very important regulatory role in the secretion of hormones related to reproductive functions and response to stress. https://www.ncbi.nlm.nih.gov/pubmed/17369778     Endocannabinoid system acts as a regulator of immune homeostasis in the gut - Study unveils a role for the endocannabinoid system in maintaining immune homeostasis in the gut/pancreas and reveals a conversation between the nervous and immune systems using distinct receptors. https://www.pnas.org/content/early/2017/04/18/1612177114.long     The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities - Recent studies have intriguingly suggested the existence of a functional ECS in the skin and implicated it in various biological processes (e.g. proliferation, growth, differentiation, apoptosis and cytokine, mediator or hormone production of various cell types of the skin and appendages, such as the hair follicle and sebaceous gland). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/     Regulation of circulating endocannabinoids associated with cancer and metastases in mice and humans - The endocannabinoid system was subject to cancer-associated regulations to an extent that led to measurable changes in circulating endocannabinoid levels, emphasizing the importance of the endocannabinoid system in the pathophysiology of cancer. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278301/     Endocannabinoid and ceramide levels are altered in patients with colorectal cancer - Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of human colorectal cancer tissues and adjacent non-tumor tissues. https://www.ncbi.nlm.nih.gov/pubmed/25975960     Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa - Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. https://academic.oup.com/ajcn/article/101/2/262/4494381     Gastric acid inhibitory and gastric protective effects of Cannabis and cannabinoids - Cannabis and/or cannabinoids protect the gastric mucosa against noxious challenge with non-steroidal anti-inflammatory drugs, ethanol as well as against stress-induced mucosal damage. Cannabis/cannabinoids might protect the gastric mucosa by virtue of its antisecretory, antioxidant, anti-inflammatory, and vasodilator properties. https://www.sciencedirect.com/science/article/pii/S1995764516300712     The use of cannabinoids as anticancer agents - In conclusion there exist solid scientific evidences supporting that cannabinoids exhibit a remarkable anticancer activity in preclinical models of cancer. Since these agents also show an acceptable safety profile, clinical studies aimed at testing them as single agents or in combinational therapies are urgently needed. Results from these studies are essential to clarify whether cannabinoids (and specifically cannabinoid-based medicines) could be helpful in the fight of cancer. https://www.sciencedirect.com/science/article/pii/S0278584615001190  

In this episode, we talk with John Malanca about cannabis! We tackle topics like, what is cannabis, how it used medically, the difference between THC and CBD, and much more! Fact: Most cancer patients do not die from cancer, but malnutrition. John’s Introduction into Medical Cannabis In 2011, father-in-law was battling stage 4 lung cancer, couldn’t eat, and was on oxygen 24/7. Doctor gave him two weeks to live. Started using a coconut oil capsule infused with raw and heated cannabis. Within 24 hours he was eating, by day 8 he was walking around the house. At the 3 month mark, switched to a full extract cannabis oil - administering a minute amount in the evening. Within 6 months he was walking, driving, and Hospice fired him as a patient! By the 9th month he had the first scan to show, “No evidence of recurrent disease." After 17 lung and brain scans showing no evidence of recurrent disease! He is still healthy and happy today - 8 years later!   United Patients Group Founded by John and Corrine Malanca to fill the information void surrounding medical cannabis. Don't sell products - strictly education and information. Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis. All courses are CNE approved continuing medical education.   What is cannabis? Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae. Also known as Hemp if less than .03% THC in the composition of the plant Three species may be recognized: Cannabis Sativa – formulations that include more uplifting, “day time” feelings Cannabis Indica - formulations that include more sedative and relaxing effects, including pain reduction  Cannabis Ruderalis - (not discussed in the interview) naturally low concentrations of THC naturally occurring, more research is being done on this variation of the species  Cannabis Hybrid - formulations that are mixes of Sativa and Indica based plants made from crossbreeding   There are currently 483 known compounds in the plant. The main psychoactive part of cannabis is tetrahydrocannabinol (THC). Although this is the main psychoactive components of the plant, it is also one of the main cannabinoids needed and used in medical treatments when Cannabis is on the protocol. Contains at least 113 cannabinoids (CBD).   Two Known Subtypes of Cannabinoid Receptors First discovered in the 1980s. Located throughout the body. Part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and more that have since been researched. These receptors are all over our body, head to toe. The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys. These receptors are thought to be one of the most widely expressed Gαi protein-coupled receptors in the brain The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. These receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.   What are Cannabinoids? A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. 113 cannabinoids have been isolated from the Cannabis plant. Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes. This interaction would lead to the entourage effect.   Medical Uses Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, as well as terpenes, to treat disease or improve symptoms relief. reduce nausea and vomiting during chemotherapy improve appetite in people with HIV/AIDS or cancer treat chronic pain and muscle spasms (MS and other nerve related pain) lessens tremors in Parkinson’s Disease control seizures reduce pain of cluster headaches in minutes cannabinoids are under preliminary research for their potential to affect stroke THC has been shown to kill cancer cells CBD has been shown to stop cancer cells and prevent the spread Many more!   Delivery Systems - Ways to Consume Medical Cannabis Sublingual absorption Topical Vaporization Suppositories Transdermal patches Edibles     Deeper Dive Resources   John Malanca: https://www.linkedin.com/in/john-malanca-7807956b https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/   United Patients Group: https://unitedpatientsgroup.com/ https://www.facebook.com/UnitedPatientsGroup/   The Sacred Plant: http://thesacredplant.online/t?orid=614242&opid=796&sid=D18L1_podcast https://www.facebook.com/oursacredplant/   Cannabis: https://en.wikipedia.org/wiki/Cannabis   Indica vs Sativa: https://www.leafly.com/news/cannabis-101/sativa-indica-and-hybrid-differences-between-cannabis-types   Ruderalis: https://www.leafly.com/news/cannabis-101/what-is-cannabis-ruderalis   Cannabinoids: https://en.wikipedia.org/wiki/Cannabinoid   Entourage Effect: https://en.wikipedia.org/wiki/Entourage_effect   Side by Side Image of Cannabis and Lyrica: https://unitedpatientsgroup.com/blog/2014/06/30/fibromyalgia-big-pharma-vs-medical-cannabis   Laws By State: https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State   Studies in 2018: Cannabis Is Safe and Effective at Treating Pain in the Elderly CBD Protects Against the Damaging Effects of Iron in Aging Brain Diseases A Case for Balanced THC and CBD in Colorectal Cancer Prevention CBD Protects Against Endometrial Cancer by Activating TRPV1 Receptors THC Enhances the Pain-Relieving Effects of Opioids in Double-Blinded, Placebo-Controlled Study THC Boosts the Efficacy of a Traditional Neuropathic Pain Medication CBD Blocks Toxin’s Ability to Promote Schizophrenia-like Symptoms Cannabis Protects Against Alcohol’s Damaging Effects on the Stomach A Balanced Cannabis Approach May Treat Spasticity in ALS Cannabis Smoke Improves Working Memory in Underperformers The Entourage Effect in Rodent-Model Breast Cancer A Deeper Understanding of Cannabis’s Anti-Nausea Effects A Shift in Cannabis & Schizophrenia Theory Clinical Trial Finds Benefits of CBD in Autism A Novel Target for Low-Dose CBD Is Identified CBD Treats Brain Changes Caused by Regular Cannabis Use Transdermal CBD for the Treatment of Non-Opioid Addictions Plant-Derived Cannabinoids Improve the Efficacy of Cancer Treatment CBD’s Fast-Acting, Long-Lasting Antidepressant Effects in Rodents Cannabis-Based Pharmaceutical Improves Symptoms of Multiple Sclerosis

In this episode, we talk with John Malanca about cannabis! We tackle topics like, what is cannabis, how it used medically, the difference between THC and CBD, and much more! Fact: Most cancer patients do not die from cancer, but malnutrition. John’s Introduction into Medical Cannabis In 2011, father-in-law was battling stage 4 lung cancer, couldn’t eat, and was on oxygen 24/7. Doctor gave him two weeks to live. Started using a coconut oil capsule infused with raw and heated cannabis. Within 24 hours he was eating, by day 8 he was walking around the house. At the 3 month mark, switched to a full extract cannabis oil - administering a minute amount in the evening. Within 6 months he was walking, driving, and Hospice fired him as a patient! By the 9th month he had the first scan to show, “No evidence of recurrent disease." After 17 lung and brain scans showing no evidence of recurrent disease! He is still healthy and happy today - 8 years later!   United Patients Group Founded by John and Corrine Malanca to fill the information void surrounding medical cannabis. Don't sell products - strictly education and information. Teach local, state, international governments, as well as local, state and international medical institutions about medical cannabis. All courses are CNE approved continuing medical education.   What is cannabis? Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae. Also known as Hemp if less than .03% THC in the composition of the plant Three species may be recognized: Cannabis Sativa – formulations that include more uplifting, “day time” feelings Cannabis Indica - formulations that include more sedative and relaxing effects, including pain reduction  Cannabis Ruderalis - (not discussed in the interview) naturally low concentrations of THC naturally occurring, more research is being done on this variation of the species  Cannabis Hybrid - formulations that are mixes of Sativa and Indica based plants made from crossbreeding   There are currently 483 known compounds in the plant. The main psychoactive part of cannabis is tetrahydrocannabinol (THC). Although this is the main psychoactive components of the plant, it is also one of the main cannabinoids needed and used in medical treatments when Cannabis is on the protocol. Contains at least 113 cannabinoids (CBD).   Two Known Subtypes of Cannabinoid Receptors First discovered in the 1980s. Located throughout the body. Part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and more that have since been researched. These receptors are all over our body, head to toe. The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys. These receptors are thought to be one of the most widely expressed Gαi protein-coupled receptors in the brain The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. These receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.   What are Cannabinoids? A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. 113 cannabinoids have been isolated from the Cannabis plant. Research shows the effect of cannabinoids might be modulated by aromatic compounds produced by the cannabis plant, called terpenes. This interaction would lead to the entourage effect.   Medical Uses Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, as well as terpenes, to treat disease or improve symptoms relief. reduce nausea and vomiting during chemotherapy improve appetite in people with HIV/AIDS or cancer treat chronic pain and muscle spasms (MS and other nerve related pain) lessens tremors in Parkinson’s Disease control seizures reduce pain of cluster headaches in minutes cannabinoids are under preliminary research for their potential to affect stroke THC has been shown to kill cancer cells CBD has been shown to stop cancer cells and prevent the spread Many more!   Delivery Systems - Ways to Consume Medical Cannabis Sublingual absorption Topical Vaporization Suppositories Transdermal patches Edibles     Deeper Dive Resources   John Malanca: https://www.linkedin.com/in/john-malanca-7807956b https://unitedpatientsgroup.com/about-cancer-and-medical-cannabis/   United Patients Group: https://unitedpatientsgroup.com/ https://www.facebook.com/UnitedPatientsGroup/   The Sacred Plant: http://thesacredplant.online/t?orid=614242&opid=796&sid=D18L1_podcast https://www.facebook.com/oursacredplant/   Cannabis: https://en.wikipedia.org/wiki/Cannabis   Indica vs Sativa: https://www.leafly.com/news/cannabis-101/sativa-indica-and-hybrid-differences-between-cannabis-types   Ruderalis: https://www.leafly.com/news/cannabis-101/what-is-cannabis-ruderalis   Cannabinoids: https://en.wikipedia.org/wiki/Cannabinoid   Entourage Effect: https://en.wikipedia.org/wiki/Entourage_effect   Side by Side Image of Cannabis and Lyrica: https://unitedpatientsgroup.com/blog/2014/06/30/fibromyalgia-big-pharma-vs-medical-cannabis   Laws By State: https://unitedpatientsgroup.com/Medical-Marijuana-Laws-By-State   Studies in 2018: Cannabis Is Safe and Effective at Treating Pain in the Elderly CBD Protects Against the Damaging Effects of Iron in Aging Brain Diseases A Case for Balanced THC and CBD in Colorectal Cancer Prevention CBD Protects Against Endometrial Cancer by Activating TRPV1 Receptors THC Enhances the Pain-Relieving Effects of Opioids in Double-Blinded, Placebo-Controlled Study THC Boosts the Efficacy of a Traditional Neuropathic Pain Medication CBD Blocks Toxin’s Ability to Promote Schizophrenia-like Symptoms Cannabis Protects Against Alcohol’s Damaging Effects on the Stomach A Balanced Cannabis Approach May Treat Spasticity in ALS Cannabis Smoke Improves Working Memory in Underperformers The Entourage Effect in Rodent-Model Breast Cancer A Deeper Understanding of Cannabis’s Anti-Nausea Effects A Shift in Cannabis & Schizophrenia Theory Clinical Trial Finds Benefits of CBD in Autism A Novel Target for Low-Dose CBD Is Identified CBD Treats Brain Changes Caused by Regular Cannabis Use Transdermal CBD for the Treatment of Non-Opioid Addictions Plant-Derived Cannabinoids Improve the Efficacy of Cancer Treatment CBD’s Fast-Acting, Long-Lasting Antidepressant Effects in Rodents Cannabis-Based Pharmaceutical Improves Symptoms of Multiple Sclerosis

Elizabeth G. Dost is a registered nurse and senior health care executive with more than 20 years’ experience in the Boston area health care market. She is currently serving as a Senior Executive Health Care Consultant to Emerging Service Industries, most noticeably in Medical Cannabis.  Ms. Dost is a Cannabis Nurse and Nominating Committee member of the American Cannabis Nurse Association, Treasurer of the Society for Cannabis Clinicians’ newly formed east location, Clinical Director of the Massachusetts Patients Advocacy Alliance, and is the Chief Operating Officer of MJ&CO, a global cannabis company, while she also consults to private entities seeking to improve lives via the medical application of and safe access to Medical Cannabis. She is a registered participant of My Compassion and the Medical Cannabis Institute.  Beth has been a featured guest on radio, and nationally, as a presenter at Patients Out of Time, United Patients Group, Women Grow Boston and Phoenix, New England Cannabis Convention, annually for the Massachusetts Federation of Hospice and Palliative Care.  Ms. Dost lends her time for interviews to numerous media outlets including but not limited to DOPE Magazine, THC Tucson, and Hemp News for Patients Out of Time to name a few.  Ms. Dost was the Vice President and Executive Director of a non-profit, multi-site hospice company promoting a culture of compassion to all persons and their loved ones seeking end of life health care and support. Sound Health Options

Elizabeth G. Dost is a registered nurse and senior health care executive with more than 20 years’ experience in the Boston area health care market. She is currently serving as a Senior Executive Health Care Consultant to Emerging Service Industries, most noticeably in Medical Cannabis.  Ms. Dost is a Cannabis Nurse and Nominating Committee member of the American Cannabis Nurse Association, Treasurer of the Society for Cannabis Clinicians’ newly formed east location, Clinical Director of the Massachusetts Patients Advocacy Alliance, and is the Chief Operating Officer of MJ&CO, a global cannabis company, while she also consults to private entities seeking to improve lives via the medical application of and safe access to Medical Cannabis. She is a registered participant of My Compassion and the Medical Cannabis Institute.  Beth has been a featured guest on radio, and nationally, as a presenter at Patients Out of Time, United Patients Group, Women Grow Boston and Phoenix, New England Cannabis Convention, annually for the Massachusetts Federation of Hospice and Palliative Care.  Ms. Dost lends her time for interviews to numerous media outlets including but not limited to DOPE Magazine, THC Tucson, and Hemp News for Patients Out of Time to name a few.  Ms. Dost was the Vice President and Executive Director of a non-profit, multi-site hospice company promoting a culture of compassion to all persons and their loved ones seeking end of life health care and support. Sound Health Options

Dawn-Marie Steenstra has always been a passionate patient advocate. She owned and operated her own assisted living in her home since the age of 20, caring for primarily deinstitutionalized psychiatric elderly women. In 1996, Dawn-Marie completed college as a practical nurse, and since 1998, has specialized in staff development, quality assurance, and infection control. Dawn-Marie learned about cannabis as a wellness option 10 months post breast cancer and thereafter jumped headlong into the industry. She has since worked with The American Cannabis Nurses Association, Patients Out of Time, Americans For Safe Access, United Patients Group, and most recently, was privileged to co-produce Season 2 of “The Sacred Plant” showcasing the alongside John Malanca in her role as National Ambassador for United Patients Group. Her goals in cannabis reform concentrate primarily on education and excellence in the practice of cannabinoid therapeutics, nursing, and business.