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Justin Penik and NYG Daily talk about everything they are seeing from New York Giants training campTOPICSTraining Camp recap The Offense with Russell Wilson Evan Neal at Right Guard Marcus Mbow at Right Tackle Is Darius Alexander ready for starting role? Banks starting CB2 over Flott? Penalties are a problem Questions from the chatUse code GIANTS2025 for 10% off your next SeatGeek order*: https://seatgeek.onelink.me/RrnK/GIANTS2025. Sponsored by SeatGeek. *Restrictions apply. Max $20 discountCheck out our Merch: https://shop.jomboymedia.com/collections/talkin-giantsSubscribe to JM Football for our NFL coverage: https://www.youtube.com/@JMFootballFollow all of our content on https://jomboymedia.com #giants #nygiants
Will Petersen and Brandon Stokley with Mark Schlereth enter the third hour raving about the competitiveness they have seen between the offense and the defense during training camp, especially without a brawl breaking out. They hear a bit of the trash talk going around the team. An emerging national outlet ranked the Broncos’ defense #1 ahead of the NFL season and the guys break down how that can happen this season. They ask Stink if he thinks Moss is still the CB2 after the Broncos drafted Jahdae Barron, his answer may surprise you. praising the young receivers like Marvin Mims, Troy Franklin, and Evan Engram for their performances in camp so far.
Will Petersen and Brandon Stokley open today’s show recapping a chippy practice from yesterday. They speculate how many more days the Broncos have of padded practice and how they’ll handle the rest of camp. Riley Moss had a breakout year in 2024 but is his job as the CB2 safe after the Broncos drafted Jahdae Barron? Will and Stoke discuss. The guys debate who should be the WR2 next to Courtland Sutton and Will ties to make the case for Marvin Mims. Another outlet is bullish on the Denver defense this season, have they shown enough in camp to back it up?
Who's shining at Buffalo Bills Training Camp? And who's struggling? In this episode of The Film Room, Erik and Anthony break down the biggest storylines from camp - from surprise standouts and rising stars to position battles and early concerns.BuffaloBills #NFL #Billsmafia ▶️ Hit subscribe for weekly X's & O's film sessions!
Retail is a brutal industry where even the massive companies, that seem impossible to topple, can crumble. Crate and Barrel has long been a household name in American retail, which shaped how generations of consumers furnish their homes. What started as a small Chicago storefront in the 1960s has grown into a $2B global brand with over 100 locations, a powerful online presence, and sister brands like CB2 and Crate & Kids that continue to redefine the home shopping experience.In this episode of The Reboot Chronicles, we sit down with Gordon Segal, the co-founder of Crate and Barrel. As the Chairman and CEO, Gordon grew Crate & Barrel into a global home furnishings powerhouse, pioneering the accessible modern design movement that rebooted American retail through experiential store layouts, minimalist merchandising, and international sourcing. A pioneer in retail, Gordon helped create an accessible, design-forward brand long before “lifestyle retail” became a thing. Follow along as Gordon reflects on Crate and Barrel's humble beginnings, keys to scaling a values-driven business, tough leadership transitions and reboots, and how staying true to culture remains a competitive advantage—even in an era of Amazon and Wayfair.
The Bills placed rookie edge rusher Landon Jackson on the Physically Unable to Perform (PUP) list entering training camp. What's it mean? Also, Carl Jones of News 4 and Ryan Talbot of the Shout podcast join to discuss the Bills' upcoming battles cornerback and safety. Can the rookie Max Hairston lock down the CB2 job? Can Cole Bishop elevate to a starter at safety? Carl and Ryan discuss that and more.Welcome to Buffalo Pregame! Your source for LIVE Buffalo sports discussion. Each week, we will dive into the latest comings and goings from both One Bills Dr. and KeyBank Center as Bills Digest editor Alex Brasky follows the Bills and Sabres with news, analysis, opinions and more.Podcast presented by ASM Publications and Bills Digest.Please subscribe to the podcast on YouTube: https://tinyurl.com/4z9mnt4pAlso please subscribe to the free Buffalo Pregame Substack: https://alexbrasky.substack.com/Follow me @AlexBrasky.
Let's round out this series by looking at two potential camp battles at two important positions First up, Deontae Banks has been pushed into the CB2 role this offseason but should he be looking over his shoulder? Then on special teams could Graham Gano be under threat after a couple of lackluster seasons? Join the lads as they talk both these points and more!
In this exciting interview (watch on YouTube), we sit down with Colonel Philip Blair, MD, (USAF Ret), CEO of Blair Medical Group, to explore the potential of β-caryophyllene (BCP)—a natural, plant-based compound—to support and even transform the treatment of Parkinson's Disease. Dr. Blair brings decades of clinical and military medical experience to the table as he explains how BCP interacts with the endocannabinoid system, reduces inflammation, and may protect neurons—offering real hope for those living with Parkinson's. In this episode, you'll learn: ✅ What is β-caryophyllene (BCP)? ✅ How BCP interacts with CB2 receptors in the brain ✅ The role of inflammation in Parkinson's and how BCP may help ✅ Clinical insights from Dr. Blair's patient experience ✅ Natural healing strategies that go beyond conventional medicine Learn more about Dr. Blair's medical practice and BCP products here (be sure to use promo code PDEDUCATION at checkout for 10% off!): https://www.blairmedicalgroup.shop/?aff=22
Anthony breaks down the New York Giants' potential battle at CB2.
Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shiloh Bigles. A certified functional nutrition counselor and founder of Level Minds CBD Health Club, joins Money Making Conversations Masterclass to discuss how CBD, functional nutrition, and holistic wellness help individuals manage pain, anxiety, and autoimmune disorders. She shares her personal experience overcoming lupus and Crohn’s disease through natural remedies.
Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shiloh Bigles. A certified functional nutrition counselor and founder of Level Minds CBD Health Club, joins Money Making Conversations Masterclass to discuss how CBD, functional nutrition, and holistic wellness help individuals manage pain, anxiety, and autoimmune disorders. She shares her personal experience overcoming lupus and Crohn’s disease through natural remedies.
The wait is over — mandatory OTAs have officially kicked off for the Cincinnati Bengals! On today's Sports with Strawberry Ice, we break down everything happening at camp: Will Trey Hendrickson report after requesting a trade? Will Shemar Stewart get his first action in practice? Joe Burrow's health and leadership as the face of the franchise Early standouts and surprise performers from OTA workouts Position battles to watch: WR3, RT, CB2, and more What this all means for the Bengals' chances at a Super Bowl run in 2025Plus, we'll give you the latest buzz coming out of Paycor Stadium as the Bengals gear up for a huge season. Drop your takes in the chat — let's talk football!#Bengals #StrawberryIce #WhoDey #BengalsOTAs #NFLNews #JoeBurrow #TreyHendrickson #ShemarStewart #BengalsCamp
Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shiloh Bigles. A certified functional nutrition counselor and founder of Level Minds CBD Health Club, joins Money Making Conversations Masterclass to discuss how CBD, functional nutrition, and holistic wellness help individuals manage pain, anxiety, and autoimmune disorders. She shares her personal experience overcoming lupus and Crohn’s disease through natural remedies.
The Buffalo Bills made headlines by re-signing Tre'Davious White to a one-year deal, raising questions about his role in 2025. Is this a feel-good reunion or just camp competition? We break down the implications, including how it affects Buffalo's draft strategy.Plus, we dive into TWO full mock drafts:Trade-back scenarios that could reshape the rosterTop defensive tackle and cornerback prospects to watchWho could replace James Cook if the Bills draft a new RB?Roster holes at DT, EDGE, and CB2—and how to fix themWhy wide receiver might still be a surprise early pickWith the draft just days away, these predictions matter more than ever. Who do YOU want Buffalo to take at pick 30? Let us know in the comments.Go Bills!The Wandering Buffalo Podcast: A Buffalo Bills Podcast for April 21st, 2025.----------------------------------Sponsored by WearBUF - Buffalo Inspired Apparelhttps://www.wearbuf.com/ Use code "TWB" at checkout for 10% off your first order.----------------------------------If you like the Buffalo Bills, Buffalo Bills news today, and other Buffalo Bills content, connect with us!Stay up to date with all things Buffalo Bills: https://www.wanderingbuf.com/ Follow us on Twitter: https://www.twitter.com/TheWanderingBuf Follow us on Instagram: https://www.instagram.com/TheWanderingBuf Like us on Facebook: https://www.facebook.com/TheWanderingBuf Subscribe to The Wandering Buffalo Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-wandering-buffalo-podcast/id1553575732 Subscribe to The Wandering Buffalo Podcast on Spotify Podcasts: https://open.spotify.com/show/7HCluqByJZqhUQD9DJE0Iq ----------------------------------Host, Justin Goddard:Twitter -- https://www.twitter.com/jgods22 Instagram -- https://www.instagram.com/jgods22 Producer, Jakob Merkel:Twitter -- https://www.twitter.com/jakobmerkel Instagram -- https://www.instagram.com/jakobmerkel ----------------------------------The Wandering Buffalo Podcast is a part of the Buffalo FAMBase, the originators of #BillsMafia.Buffalo FAMBase is your #1 source for all of your Buffalo Bills news, Buffalo Bills updates, and everything else to do with the Buffalo Bills.Buffalo FAMBase Podcast Network: https://anchor.fm/buffalofambaseBuffalo FAMBase on YouTube: https://www.youtube.com/channel/UCu_JTz1SmD0Ml3D10HVQ50g Final 2025 Buffalo Bills Mock Draft: Bills Could Draft a STAR#BuffaloBills #GoBills #BillsMafia
The Buffalo Bills made headlines by re-signing Tre'Davious White to a one-year deal, raising questions about his role in 2025. Is this a feel-good reunion or just camp competition? We break down the implications, including how it affects Buffalo's draft strategy.Plus, we dive into TWO full mock drafts:Trade-back scenarios that could reshape the rosterTop defensive tackle and cornerback prospects to watchWho could replace James Cook if the Bills draft a new RB?Roster holes at DT, EDGE, and CB2—and how to fix themWhy wide receiver might still be a surprise early pickWith the draft just days away, these predictions matter more than ever. Who do YOU want Buffalo to take at pick 30? Let us know in the comments.Go Bills!The Wandering Buffalo Podcast: A Buffalo Bills Podcast for April 21st, 2025.----------------------------------Sponsored by WearBUF - Buffalo Inspired Apparelhttps://www.wearbuf.com/ Use code "TWB" at checkout for 10% off your first order.----------------------------------If you like the Buffalo Bills, Buffalo Bills news today, and other Buffalo Bills content, connect with us!Stay up to date with all things Buffalo Bills: https://www.wanderingbuf.com/ Follow us on Twitter: https://www.twitter.com/TheWanderingBuf Follow us on Instagram: https://www.instagram.com/TheWanderingBuf Like us on Facebook: https://www.facebook.com/TheWanderingBuf Subscribe to The Wandering Buffalo Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-wandering-buffalo-podcast/id1553575732 Subscribe to The Wandering Buffalo Podcast on Spotify Podcasts: https://open.spotify.com/show/7HCluqByJZqhUQD9DJE0Iq ----------------------------------Host, Justin Goddard:Twitter -- https://www.twitter.com/jgods22 Instagram -- https://www.instagram.com/jgods22 Producer, Jakob Merkel:Twitter -- https://www.twitter.com/jakobmerkel Instagram -- https://www.instagram.com/jakobmerkel ----------------------------------The Wandering Buffalo Podcast is a part of the Buffalo FAMBase, the originators of #BillsMafia.Buffalo FAMBase is your #1 source for all of your Buffalo Bills news, Buffalo Bills updates, and everything else to do with the Buffalo Bills.Buffalo FAMBase Podcast Network: https://anchor.fm/buffalofambaseBuffalo FAMBase on YouTube: https://www.youtube.com/channel/UCu_JTz1SmD0Ml3D10HVQ50g Final 2025 Buffalo Bills Mock Draft: Bills Could Draft a STAR#BuffaloBills #GoBills #BillsMafia
The Buffalo Bills enter the 2025 NFL Draft with a glaring need at cornerback. While Christian Benford has solidified the CB1 spot, the CB2 position remains wide open—and fans are debating whether Brandon Beane should invest early or stick to his usual late-round magic. In this episode, we break down five potential cornerback targets who could reshape Buffalo's defense in 2025.Could the Bills finally take a swing on a top-tier corner in the first round? Or will a smart tradeback unlock new options? We analyze every angle, from Savion Riley's upside to Will Johnson's draft stock, and how late-season injuries and free agency still factor into the final decision.Topics Covered:CB2: The Bills' most underrated roster holeTop CB prospects in the 2025 NFL DraftInjury concerns, draft value & fit in McDermott's systemCould the Bills trade up or back in Round 1?Free agents still in play: Asante Samuel Jr., Rasul Douglas & moreWhat's your ideal CB pick for Buffalo this year? Drop your thoughts in the comments below.Go Bills!The Wandering Buffalo Podcast: A Buffalo Bills Podcast for April 8th, 2025.----------------------------------Sponsored by WearBUF - Buffalo Inspired Apparelhttps://www.wearbuf.com/ Use code "TWB" at checkout for 10% off your first order.----------------------------------If you like the Buffalo Bills, Buffalo Bills news today, and other Buffalo Bills content, connect with us!Stay up to date with all things Buffalo Bills: https://www.wanderingbuf.com/ Follow us on Twitter: https://www.twitter.com/TheWanderingBuf Follow us on Instagram: https://www.instagram.com/TheWanderingBuf Like us on Facebook: https://www.facebook.com/TheWanderingBuf Subscribe to The Wandering Buffalo Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-wandering-buffalo-podcast/id1553575732 Subscribe to The Wandering Buffalo Podcast on Spotify Podcasts: https://open.spotify.com/show/7HCluqByJZqhUQD9DJE0Iq ----------------------------------Host, Justin Goddard:Twitter -- https://www.twitter.com/jgods22 Instagram -- https://www.instagram.com/jgods22 Producer, Jakob Merkel:Twitter -- https://www.twitter.com/jakobmerkel Instagram -- https://www.instagram.com/jakobmerkel ----------------------------------The Wandering Buffalo Podcast is a part of the Buffalo FAMBase, the originators of #BillsMafia.Buffalo FAMBase is your #1 source for all of your Buffalo Bills news, Buffalo Bills updates, and everything else to do with the Buffalo Bills.Buffalo FAMBase Podcast Network: https://anchor.fm/buffalofambaseBuffalo FAMBase on YouTube: https://www.youtube.com/channel/UCu_JTz1SmD0Ml3D10HVQ50g Why the Buffalo Bills Locked In Christian Benford Early: Smartest Move of the Offseason?#BuffaloBills #GoBills #BillsMafia
The Buffalo Bills enter the 2025 NFL Draft with a glaring need at cornerback. While Christian Benford has solidified the CB1 spot, the CB2 position remains wide open—and fans are debating whether Brandon Beane should invest early or stick to his usual late-round magic. In this episode, we break down five potential cornerback targets who could reshape Buffalo's defense in 2025.Could the Bills finally take a swing on a top-tier corner in the first round? Or will a smart tradeback unlock new options? We analyze every angle, from Savion Riley's upside to Will Johnson's draft stock, and how late-season injuries and free agency still factor into the final decision.Topics Covered:CB2: The Bills' most underrated roster holeTop CB prospects in the 2025 NFL DraftInjury concerns, draft value & fit in McDermott's systemCould the Bills trade up or back in Round 1?Free agents still in play: Asante Samuel Jr., Rasul Douglas & moreWhat's your ideal CB pick for Buffalo this year? Drop your thoughts in the comments below.Go Bills!The Wandering Buffalo Podcast: A Buffalo Bills Podcast for April 8th, 2025.----------------------------------Sponsored by WearBUF - Buffalo Inspired Apparelhttps://www.wearbuf.com/ Use code "TWB" at checkout for 10% off your first order.----------------------------------If you like the Buffalo Bills, Buffalo Bills news today, and other Buffalo Bills content, connect with us!Stay up to date with all things Buffalo Bills: https://www.wanderingbuf.com/ Follow us on Twitter: https://www.twitter.com/TheWanderingBuf Follow us on Instagram: https://www.instagram.com/TheWanderingBuf Like us on Facebook: https://www.facebook.com/TheWanderingBuf Subscribe to The Wandering Buffalo Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-wandering-buffalo-podcast/id1553575732 Subscribe to The Wandering Buffalo Podcast on Spotify Podcasts: https://open.spotify.com/show/7HCluqByJZqhUQD9DJE0Iq ----------------------------------Host, Justin Goddard:Twitter -- https://www.twitter.com/jgods22 Instagram -- https://www.instagram.com/jgods22 Producer, Jakob Merkel:Twitter -- https://www.twitter.com/jakobmerkel Instagram -- https://www.instagram.com/jakobmerkel ----------------------------------The Wandering Buffalo Podcast is a part of the Buffalo FAMBase, the originators of #BillsMafia.Buffalo FAMBase is your #1 source for all of your Buffalo Bills news, Buffalo Bills updates, and everything else to do with the Buffalo Bills.Buffalo FAMBase Podcast Network: https://anchor.fm/buffalofambaseBuffalo FAMBase on YouTube: https://www.youtube.com/channel/UCu_JTz1SmD0Ml3D10HVQ50g Why the Buffalo Bills Locked In Christian Benford Early: Smartest Move of the Offseason?#BuffaloBills #GoBills #BillsMafia
The Buffalo Bills' offseason took a shocking turn as two newly signed free agents are suspended for six games. With key signings like Joey Bosa and lingering questions at cornerback, how will this impact Buffalo's Super Bowl hopes? Plus, we break down the latest Stefon Diggs rumors—could a reunion actually happen?Topics Covered:- How the Bills' free agency plan just got complicated- Joey Bosa signing: Boom or bust?- Are the Bills' biggest needs still unaddressed?- The CB2 dilemma: Will Buffalo draft a corner in Round 1?- The Diggs debate: Would you take him back?What's your biggest concern heading into the 2025 season? Drop your thoughts in the comments!---------------------------------------------------If you like the Buffalo Bills, Buffalo Bills news today, and other Buffalo Bills content, connect with us!Stay up to date with all things Buffalo Bills: https://www.wanderingbuf.com/ Support The Wandering Buffalo Podcast: A Buffalo Bills Podcast: https://anchor.fm/wandering-buffalo-podcast/support Follow us on Twitter: https://www.twitter.com/TheWanderingBuf Follow us on Instagram: https://www.instagram.com/TheWanderingBuf Like us on Facebook: https://www.facebook.com/TheWanderingBuf Subscribe to The Wandering Buffalo Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-wandering-buffalo-podcast/id1553575732 Subscribe to The Wandering Buffalo Podcast on Spotify Podcasts: https://open.spotify.com/show/7HCluqByJZqhUQD9DJE0Iq ----------------------------------Host, Justin Goddard:Twitter -- https://www.twitter.com/jgods22 Instagram -- https://www.instagram.com/jgods22 Producer, Jakob Merkel:Twitter -- https://www.twitter.com/jakobmerkel Instagram -- https://www.instagram.com/jakobmerkel ----------------------------------The Wandering Buffalo Podcast is a part of the Buffalo FAMBase, the originators of #BillsMafia.Buffalo FAMBase is your #1 source for all of your Buffalo Bills news, Buffalo Bills updates, and everything else to do with the Buffalo Bills.Buffalo FAMBase Podcast Network: https://anchor.fm/buffalofambaseBuffalo FAMBase on YouTube: https://www.youtube.com/channel/UCu_JTz1SmD0Ml3D10HVQ50g Buffalo FAMBase on Instagram: https://www.instagram.com/buffalofambase/ Buffalo FAMBase on Twitter: https://twitter.com/buffalofambase Buffalo FAMBase on Facebook: https://www.facebook.com/BuffaloFAMbase The Wandering Buffalo Podcast: A Buffalo Bills Podcast#BuffaloBills #GoBills #BillsMafia
This week on TABLE TALK, Jeff sat down with Brenden Deeg from TheScore.com t to discuss and dissect the Philadelphia Eagles' offseason thus far. What have we learned about how the Birds may draft next month? Will there be a competition in the future at the safety and cornerback positions with young, up and coming talent? Topics that Brenden and Jeff dove into- How the Eagles front office has grown over the years, and what their place is within the NFL ranks at this point here in 2025.- Concerns about the safety position on defense heading into next season as a hole has been generated with no C.J. Gardner-Johnson.- Who may be CB2 on the Eagles defense?- Does the storyline about trading TE Dallas Goedert and DE Bryce Huff have legs?All of this and much more this week on Table Talk!Head over to our website for all of our podcasts and more: philadelphiasportstable.com.Follow us on BlueSky:Jeff: @jeffwarren.bsky.socialErik: @brickpollitt.bsky.socialFollow us on Threads:Jeff: @mrjeffwarrenErik: @slen1023The Show: @philadelphiasportstableFollow us on Twitter/X:Jeff: @Jeffrey_WarrenErik: @BrickPollittThe Show: @PhiladelphiaPSTFollow the show on Instagram: instagram.com/philadelphiasportstable.
The guys discuss the news that Mike Hughes is back as CB2 after signing a 3-year deal worth $18 million
Send us a textThe New York Giants have made some major moves, and Drew and Rob are here to break it all down in another jam-packed episode of 2 Giants Goofballs: New York Giants News & Updates. With free agency in full swing, the Giants have re-signed a familiar face, added key pieces on defense, and continue to be linked to the biggest quarterback names in the NFL. This episode dives deep into all the latest Giants news, rumors, and updates as the team looks to reshape its roster for the 2025 season. The show kicks off with the Giants re-signing wide receiver Darius Slayton to a three-year, $36 million deal. After finishing the 2023 season with 39 catches for 573 yards and two touchdowns, Slayton remains a solid part of the Giants' receiving corps. What does this signing mean for the offense, and could it indicate what direction the Giants will go in the draft? Next, the Giants addressed a major need on defense by signing cornerback Paulson Adebo. The former Saints CB, who played at Stanford alongside Bobby Okereke, comes to New York after an injury-limited season in which he recorded 52 tackles and three interceptions in just seven games. While he has been a solid CB2 for most of his career, his aggressive playstyle and struggles against the run could be a concern. The initial reports on his contract were all over the place, ranging from three years, $30 million to three years, $54 million, with conflicting details on guarantees. The guys break down what Adebo brings to the Giants and whether this signing is a bargain or an overpay. The defensive reinforcements didn't stop there, as the Giants also signed veteran defensive lineman Roy Robertson-Harris to a two-year, $10 million deal. Standing at 6'5” and 290 pounds, the 31-year-old spent last season with both the Jaguars and Seahawks, appearing in 17 games with two starts. He recorded 20 tackles, four tackles for loss, two sacks, and five QB hits while playing 34 percent of defensive snaps. While his PFF grades weren't impressive, Robertson-Harris brings experience and depth to a defensive line that needed reinforcements. Could this be the first step in rebuilding the defensive front, or is this simply a depth move? One of the biggest topics of the episode revolves around the ongoing quarterback carousel. The Giants are still waiting on a decision from Aaron Rodgers, who has been linked to both New York and the Pittsburgh Steelers. While Rodgers takes his time deciding his future, other quarterbacks have already landed in new homes. Zach Wilson is heading to the Dolphins, Josh Dobbs is joining the Patriots, and Kenny Pickett was traded from the Eagles to the Browns. Meanwhile, Justin Fields signed with the Jets, Sam Darnold is now a Seahawk, and Jimmy Garoppolo is staying with the Rams. With Jameis Winston in talks with the 49ers and Chargers, and Russell Wilson considering the Titans, the quarterback market is rapidly changing. Drew and Rob debate whether the Giants should be waiting on Rodgers or if they should pursue other options. Could Kirk Cousins still be in play? The episode then shifts to a disturbing off-field story as Odell Beckham Jr. finds himself named in a lawsuit. #giantsSupport the showAll Episodes are shot LIVE with fan interactions on Youtube, Facebook, Twitter, & TwitchSponsor the show at: https://www.buymeacoffee.com/2giantgoofballsInterested in starting a podcast. We recommend using buzzsprout: https://www.buzzsprout.com/?referrer_id=2012368
In the late 1990s Glenn Lawson and Grant Fenning made a reputation for themselves as canny vintage pickers. Over time, their own furniture designs came to the forefront, and the two became a trusted resource for top Los Angeles designers. Now Lawson Fenning is opening up an outpost in New York and collaborating with DWR and CB2. On this episode of the podcast, Lawson and Fenning speak with host Dennis Scully about purposefully staying a little under the radar, why they only had to show at ICFF once, and their strategy for dealing with copycats and dupes. This episode is sponsored by Ernesta and CryptonLINKSLawson-FenningDennis ScullyBusiness of Home
The Endocannabinoid System plays a crucial role in regulating cardiovascular, neurological, and immune functions through CB1 and CB2 receptors. • CB1 Activation: Associated with oxidative stress, inflammation, and increased cardiovascular risks such as myocardial infarction (MI), arrhythmias, and heart failure. • CB2 Activation: Primarily found in immune cells and linked to anti-inflammatory and protective cardiovascular effects. • Cannabis Use: High THC content or synthetic cannabinoids (e.g., Spice, K2) significantly increases the risk of cardiovascular diseases and psychiatric disorders. • Cannabis Use Disorder (CUD): Characterized by compulsive use despite adverse consequences, often co-occurring with depression, PTSD, and anxiety. • Potential Therapeutic Targets: CB1 antagonists (e.g., Genistein) and CB2 agonists are being explored for their ability to reduce inflammation and vascular damage while minimizing psychiatric side effects. Future research is needed to clarify long-term cardiovascular effects, optimize cannabinoid therapies, and inform public health policies.
In this episode, I am talking about how I got my first period post Jesse. This is the first time postpartum period has come back this early for me! I am sharing the details and how I am handling periods better this time around! In this episode I discuss: CB2 broken chair Heart and Hustle: Starts 2/2 4 Weeks of meal planning with grocery lists, recipes for Meal Prep What shows I watched Soul pms gummy CODE KIMPERRY Rookie recovery CODE KIMPERRY Period Underwear: My favorite brand is Revol (WORKING ON GETTING US A CODE) Cozy bins for periods! Cozy Earth CODE GLOWING for 40% off! Tips for Periods Links you'll want from this episode!Soul CBD code KIMPERRY Tula code KIMPERRY Dime code PERRY20 Shop kimperryco on LTK Join Heart and Hustle Starting 2/2 4 Weeks of Workouts, 4 Weeks of meal planning with grocery lists, recipes, and price breakdowns. Today's Sponsor: Cozy Earth is comfortable sheets, clothing, bedding and more that helps you make the most of being cozy because mama, Good Sleep and comfort is key! CODE GLOWING for 40% off! Have anything you want to share? Email me at podcast@kimperry.com. Don't miss out on My Freebies for Moms! ✨ After Baby Fitness Guide: A step-by-step plan to help you ease back into fitness postpartum, regain your strength, and feel like YOU again. Perfect for new moms ready to prioritize their wellness. Get the Free Guide Here
This week, we're joined by Erica Fischbach, Director of Colorado Ballet Academy, to talk about the school's full-time training programs, including the trainee and studio company levels. While the studio company is part of the main company, Erica shares everything you need to know about it. We also discuss how CBA recruits dancers, what interested students can do to be considered for admission, as well as the performance opportunities available at each level. Plus, Erica explains why Colorado Ballet Academy chooses to compete and how it benefits their dancers. Whether you're aiming for a spot in the studio company or looking to join the Academy, this episode has the details you need! You can learn more about Colorado Ballet Academy at these links: Colorado Ballet Summer Intensive Programs Young Dancer Workshop - be sure to read about CBA's new family friendly housing opportunity for young dancers! More Links: Support Ballet Help Desk Buy Corrections Journals Instagram: @BalletHelpDesk Facebook: BalletHelpDesk Ballet Help Desk Music from #Uppbeat: https://uppbeat.io/t/ian-aisling/new-future License code: MGAW5PAHYEYDQZCI
Episode 181: Cannabinoid Hyperemesis SyndromeFuture Dr. Johnson explains the pathophysiology, assessment, and management of Cannabinoid Hyperemesis syndrome. Dr. Arreaza adds some insights on the topic. Written by Tyler Johnson, MSIV, Western University of Health Sciences, College of Osteopathic Medicine of the Pacific-Northwest. Editing and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Definition Cannabinoid hyperemesis syndrome (CHS) is a syndrome of cyclic abdominal pain, vomiting, or nausea in older adolescents and adults who have chronic ϲаnոаbis use.The term “marijuana” is considered racist by some people. In the 1930s, American politicians popularized the term “marijuana” in the U.S. to portray the drug as a “Mexican vice” and to have a justification to persecute Mexican immigrants. Epidemiology The overall prevalence of cannabinoid hyperemesis syndrome is unknown due to a lack of definitive criteria or diagnostic tests. It occurs in a population that may not disclose substance use. One study conducted in 2015 in a United States urban emergency department not named, found one-third of patients with near-daily cannabis use met criteria for having had CНЅ in the prior six months.Why are rates of CHS increasing?Between 2005-2014 hospitalizations cyclic vomiting syndromes increased by 60 %. concurrent cannabis use in hospitalized patients increasing from 2 to 21 percent. 7 years after the commercialization of cannabis in Canada, the Canadian health services found a 13-fold increase in cyclic vomiting syndromesPotential correlations for the increase in CHS are increased legalization and commercialization of cannabis, higher tetrahydrocannabinol concentrations in cannabis products, and increased recognition of the syndrome.Legal status of Cannabis in the USCannabis is legal in 24 states: Alaska, Arizona, California, Colorado, Connecticut, Delaware, Illinois, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nevada, New Jersey, New Mexico, New York, Ohio, Oregon, Rhode Island, Vermont, Virginia, and Washington. It is also legal in Washington, D.C. Cannabis is approved for medical use in 38 states.Federal level: Cannabis is a Schedule I drug, under the Controlled Substance Act (added in 1970) in the group of Hallucinogenic or psychedelic substances. Tetra-hydro-cannabinol (THC, a “mind-altering substance in cannabis”) is on the same list. However, cannabidiol (CBD, derived from hemp or non-hemp plants) was removed from the Controlled Substances Act in 2018. CBD is FDA-approved (under the name of Epidiolex®) to treat rare seizure disorders. CBD is still on the list of controlled substances in some states. I see THC as a problem.THC increased concentration As recreational Cannabis becomes more normalized, innovators look to find new ways to differentiate their product and increasing THC has become a common way to perform this similar to alcohol content in the beer, wine, and liquor industry. An article by Yale School of Medicine titled “Marijuana: Rising THC Concentrations in Cannabis Can Pose Health Risks” states, “In 1995, the average THC content in cannabis seized by the Drug Enforcement Administration was about 4%. By 2017, it had risen to 17% and continues to increase. Beyond the plant, a staggering array of other cannabis products with an even higher THC content like dabs, oils, and edibles are readily available—some as high as 90%.”Recently, cannabis-infused water started to be sold in some grocery stores.Pathophysiology of CHSIt is not entirely understood. Some suggest multifactorial involving cannabinoid metabolism, exposure dose and tolerance modifying receptor regulation, complex pharmacodynamics at Cannabinoid receptors, and even changes in genetics and cannabinoid variation in plants. CB1 receptors are involved in gastric secretion, sensation, motility, inflammation, and lipogenesis. The activation of CB1 and CB2 receptors has been suggested as the possible cause of CHS.Risk FactorsCHS can occur after acute or acute on chronic use but many report daily 3-5x cannabis use cannabis use over one year and many over at least two years. Median age 24 years. Interesting factsMedical visits for inhaled cannabis are more likely associated with CHS while edibles are more likely for acute psychiatric reactions.Also, CHS is a paradoxical effect since cannabis and cannabinoid receptor agonists are known antiemetics (as seen in nabilone and dronabinol (synthetic analogs of THC)) and prescribed by some physicians to combat chemotherapy effects.Clinical Features of CHSCyclical pattern with abdominal pain, severe nausea, and vomiting up to 30 episodes daily. Pain is intense and even referred to as “scromiting” due to its intense nature, causing patients to scream and vomit concurrently.Typically, it presents with 2 or more episodes over a 6-month period with no symptoms in between. It starts within 24 hours of last cannabis use (differentiating from cannabis withdrawal) and occurs at day or night. There is a gradual symptom resolution of nausea and vomiting after several days of cannabis cessation. Some patients had symptoms 2 days to 2 weeks after cessation. Diagnosis of CHSClinical diagnosisRule out neurological symptoms such as migraine headaches, acute abdomen, motion sickness, and medications, such as recent antibiotics and chemotherapy.Often the diagnosis is discovered with a thorough history reporting a decrease in symptoms with hot showers/baths.Management of CHS AcuteRehydrate with Fluids Dopamine Antagonists– Droperidol (0.625 or 1.25mg) /Haloperidol (0.05 to 0.1mg/kg with max dose of 5mg initially) favored over typical antiemetics like Zofran or Reglan.If needed, combine with an antiemetic like metoclopramide IM or ondansetron IV and consider patients' dehydration status likely requiring US-guided IV.Topical capsaicin cream 0.025 – 0.1% on the abdomen. Long term97% resolution of symptoms completely in a systematic review of patients who stopped cannabis use.Reinforce it may take several weeks of abstinence for symptoms to resolve and symptoms can worsen if cannabis is resumed. It is unknown if a reduction in use can prevent recurrence.Approaches in the clinicEducate patients on the etiology of their symptoms with complete cessation of cannabis use.Consider referral to counseling for cannabis use disorder and abstinence support for treatment-seeking cannabis users. Approach topics such as changing one's environment, seeking social support, and using self-help techniques to non-treatment-seeking individuals.Consider referring patients with polysubstance use and significant comorbidities to a supervised withdrawal management setting. Conclusion: Cannabis use is increasing with legalization and commercialization across the United States. With increased use, Cannabinoid hyperemesis syndrome incidence increases. Often it can be diagnosed with a thorough history including chronic cannabis consumption and symptomatic relief by showers. Physicians will need to develop counseling approaches to better understand CHS patients and how to approach an often-difficult topic.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Angulo MI. Cannabinoid Hyperemesis Syndrome. JAMA. 2024;332(17):1496. doi:10.1001/jama.2024.9716. Link: https://jamanetwork.com/journals/jama/fullarticle/2824833#:~:text=Cannabinoid%20hyperemesis%20syndrome%20(CHS,last%20less%20than%201%20week.Backman, Isabella, Marijuana: Rising THC Concentrations in Cannabis Can Pose Health Risks, Yale School of Medicine, August 30, 2023. https://medicine.yale.edu/news-article/not-your-grandmothers-marijuana-rising-thc-concentrations-in-cannabis-can-pose-devastating-health-risks/Buchanan, Jennie A and George Sam Wang, Cannabinoid Hyperemesis Syndrome, Up To Date, updated July 17, 2024. https://www.uptodate.com/contents/cannabinoid-hyperemesis-syndromeTheme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.
The Chiefs haven't been able to put a team away for months, so why should anyone think Sunday's game at Cleveland will be anything but a nail-biter?Jeff Chadiha (NFL Network/NFL.com/@JeffriChadiha), Sam McDowell (Kansas City Star/KCStar.com/@SamMcDowell11) and Soren Petro (Sports Radio 810 - WHB/810whb.com/@SorenPetro) break down the Chiefs and Browns...- How concerned should the Chiefs be with the Browns?- What does Left Tackle look like this week?- Can the Chiefs slow down Myles Garrett?- Will KC make the run a priority on offense this week?- Is more "hurry up" offense the answer for the Chiefs?- Are the Secndary problems bigger than CB2?- With Belichick gone to college is Andy Reid ready to break the Win Record?- Keys to the game.- Predictions!
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Ron Hughley is back with another edition of The Daily Fix: - Hopkins already paying off. - Chiefs have problems at CB2. - For 5 minutes we were down to Carson Wentz. Subscribe: https://youtube.com/live/dKM2EFguGd4 Learn more about your ad choices. Visit megaphone.fm/adchoices
In the patient populations treated by neurologists, central neuropathic pain develops most frequently following spinal cord injury, multiple sclerosis, or stroke. To optimize pain relief, neurologists should have a multimodal and individualized approach to manage central neuropathic pain. In this episode, Lyell K. Jones Jr, MD, FAAN, speaks with Charles E. Argoff, MD, author of the article “Central Neuropathic Pain,” in the Continuum October 2024 Pain Management in Neurology issue. Dr. Jones is the editor-in-chief of Continuum: Lifelong Learning in Neurology® and is a professor of neurology at Mayo Clinic in Rochester, Minnesota. Dr. Argoff is a professor of neurology and vice chair of the department of neurology, director of the Comprehensive Pain Management Center, and director of the Pain Management Fellowship at Albany Medical College in Albany, New York. Additional Resources Read the article: Central Neuropathic Pain Subscribe to Continuum: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @LyellJ Full episode transcript available here Dr Jones: This is Doctor Lyell Jones, Editor-in-Chief of Continuum, the premier topic-based neurology clinical review and CME journal from the American Academy of Neurology. Thank you for joining us on Continuum Audio, which features conversations with Continuum's guest editors and authors who are the leading experts in their fields. Subscribers to the Continuum Journal can read the full article or listen to verbatim recordings of the article and have access to exclusive interviews not featured on the podcast. Please visit the link in the episode notes for more information on the article, subscribing to the journal, and how to get CME. Dr Jones: This is Doctor Lyell Jones, Editor-in-Chief of Continuum: Lifelong Learning in Neurology. Today I'm interviewing Dr Charles Argoff, who recently authored an article on central neuropathic pain in the latest issue of Continuum covering pain management. Dr Argoff is a neurologist at Albany Medical College where he's a professor of Neurology, and he serves as vice chair of the Department of Neurology and program director of the Pain Medicine Fellowship Program there. Dr Argoff, welcome. Thank you for joining us today. Why don't you introduce yourself to our listeners? Dr Argoff: I'm Charles Argoff. It's a pleasure to be here and thank you so much for that kind introduction. Dr Jones: I've read your article. Many of our listeners are going to read your article. Wonderful article, extremely helpful. Closes a lot of gaps, I think, that exist in our field about understanding central neuropathic pain, treating central neuropathic pain. You now, Doctor Argoff, you have the attention of a huge audience of mostly neurologists. What's the biggest point you would like to make to them, or the most important practice-changing advice that you would give to them? Dr Argoff: I think it's at least twofold. One is that central neuropathic pain is not as uncommon as you think it might be, and it occurs in a variety of settings that are near and dear to a neurologist's heart, so to speak. And secondly, although we live in an evidence-based world and we want to practice evidence-based medicine - and I'm proud to have formerly been a member of the Quality Standard subcommittee, which I think has changed its name over time. And so, I understand the importance of, you know, treatment based upon evidence - the true definition of evidence-based medicine is using the best available evidence in making decisions about individual patients. And so, I would urge those who are listening that, although there might not be as robust evidence currently as you'd like, please don't not take the time to try to treat the patient in front of you o r at least acknowledge the need for treatment and work with your colleagues to address the significant neuropathic pain associated with that central neurological disorder. Because it can be life-changing in a positive way to make even a dent and to really work with somebody, even though not clear-cut always what's going to work for an individual patient. Dr Jones: Well said. I'm glad you brought that up. So, to put it a different way, absence of evidence is not an excuse for absence of treatment. Right? Dr Argoff: Exactly. And I think that, I hope that we would agree that especially in neurology, what we do is about as far from, ‘Yep, you've got strep throat, here's that antibiotic that's going to work for you and all you have to do is take the medicine.' I mean, most of what we do is nowhere near that. Dr Jones: It's complicated stuff. And this is a complicated topic. And I'll tell you, I learned a lot reading your article. I think most of us in neurology and medicine, when we hear the term neuropathic pain, it feels roughly synonymous with peripheral generators of that pain, such as diabetic neuropathy or posttraumatic neuralgia. But as you mentioned, there's central mechanisms for pain generation. How is it defined? What is central neuropathic pain? Dr Argoff: It's defined as pain caused by a lesion or disease of the central somatosensory system . Though neuropathic pain in general is pain associated with the lesion of the somatosensory system; and to your point, that can be peripheral, which of course is outside the spinal cord, or brain or central, which is within the spinal cord or brain. And central neuropathic pain is defined specifically as pain caused by a lesion or disease of the central somatosensory system. That's either brain or spinal cord. But there's an interesting follow-up, and I'm going to ask if you could remind me because I know we're talking about definitions now, but I'll just bring something up and we can come back to it. What's interesting about that is that my - whoever 's listening, that's not to say that they're not connected. And in fact, they are very much connected. And there's very new work, which I included in the article, down at Washington University in Saint Louis, that suggests you can actually affect central neuropathic pain by addressing peripheral input to the central nervous system. If you remember Ken Casey at the University of Michigan at the World Pain Congress in Vancouver, British Columbia many years ago, he ended his talk on pain with a limerick, of which the last line was, Remember, there ain't no such thing as pain without a brain. And so that kind of summarizes that. Dr Jones: Well, and it goes both ways too, right? We know that there's some central sensitization that can happen with peripheral generators, right? So we really have to think about the whole circuit. Dr Argoff: Yes. And that's been sometimes the bane of my existence as a colleague of others and a sometimes debater. Is the pain central? Is it peripheral? Well, it's everything. And it's important to know as many of the mechanisms and many of the targets that you could use for treatment so that you can affect the best outcome for your patients. Dr Jones: Yeah, so - and you mentioned in your article what some of the common causes of central neuropathic pain are. What are the big ones in your experience? Dr Argoff: So, the biggest ones are spinal cord injury-related pain, MS-related pain - and I'd like to come back to a point and just if I do the third one - and central poststroke pain. And what struck me, I think Tim Vollmer published a survey about the incidence, the prevalence of ongoing pain in patients with multiple sclerosis. And it blew my mind several years ago because it was incredibly high. Like in this survey of MS patients who, you never hear about pain, you hear about these modifying treatments, all the wonderful expanses that have been made. I mean, like seventy something percent of people say they have moderate to severe pain. And when you think about how sensory processing occurs, it makes perfect sense that a demyelinating disorder is going to interrupt the flow of information for a person to feel normal. Dr Jones: Yeah, I think it's a good example of, there are things that we tend to focus on as clinicians where we worry about deficit and function and capacity. But if we're patient-centered and we ask patients what they care about, pain usually moves up higher on the list. And so, I think that's why we, it's maybe underrecognized with some of those central disorders, right? Dr Argoff: I think so, and I and I think you hit the nail on the head that - and we're also trained that way. I tell this to my patients very often so that they are reassured when I examine them and I say, and I tell them that everything looked pretty OK. It's not a medical term, I understand that. Because what we do in a typical neurological exam, even if it's detailed, doesn't really address all the intricacies of the nervous system. So it's really a big picture and sensory processing and especially picking up sensory deficits; you know, we use quantitative sensory testing and research studies and things like that, but bedside testing may not reveal the subtle changes. And when we don't see overt changes, we often think - that can lead someone to think that everything is OK and it's not. Dr Jones: So, when you when you see a patient who you've diagnosed with a central mechanism, so central neuropathic pain, how do you approach the management of those patients, Dr Argoff? Dr Argoff: I always review what treatments and what approaches have been addressed already. And I see if - a handful of time, we actually just submitted a paper for publication regarding this in a group of patients with pelvic pain who had untreated, difficult-to-treat chronic pelvic pain, seen all the urological kinds, gynecological things. Look, we picked up two patients who had unknown MS. So, it's just interesting when it comes down to that level. And we also picked up some patients who had subacute combined degeneration. So that's another central kind of disorder as well. Again, the neurologist in us says to make sure that we have specific diagnosis that underlies the central neuropathic pain. And so interestingly, of course, for somebody with MS - or even though it's uncommon, it could be more than one. Somebody with MS might have a stroke, somebody with MS might have a cord injury due to cervical, you know, joint disc disease. Not to overcomplicate things. Know the lay of the land, know the conditions, know what you're battling and lay out so that you can treat the treatable; you want to treat whatever you can correct? So, for MS you simply want to have the best disease-modifying treatment on board, tolerable and appropriate for that person, and so on. And then you really want to take a history of past treatments - and your treatments can be everything and anything, including behavioral modification, physical rehabilitative approaches, as well as pharmacologic management. That's - as I think I put in my article, we concentrated in the article on pharmacologic management because honestly, that's what most patients are looking for, is ‘what can we, what can you do to help me now, in addition to what I can do myself.' And that's what we typically think of. There are also some more interventional approaches, invasive options, that have developed over time. And of course, those are the ones, some of them, especially in neuromodulation, that we have the least information about, but it appears somewhat promising. Dr Jones: No, that's exactly what we need to hear. And you also mentioned something that I think is important. This is a common theme throughout the issue because I think it's true for the management of many different types of pain and interdisciplinary approach. In other words, not just honing in on pharmacotherapy or neuromodulation as a one-size-fits-all magic pill, right? So, that - tell us a little bit more about that interdisciplinary approach and how that's important for these patients. Dr Argoff: So, let me back up and give an example. Let's look at Botox for chronic migraine. So, the pre-M studies that led to the approval of Botox for chronic migraine: two treatment sessions versus two random, two placebo session in different patients. The mean headache frequency was, let's say, fifteen to twenty in each group. It was like seventeen, eighteen, something like that. But the mean pain headache day reduction was somewhere between four and five after two treatments compared to a lesser, a lower number in the placebo group. So, if you think about that, that means that you went from nineteen, let's say, to fourteen, thirteen, or twelve. Want to be generous, eleven or ten. But that means that person, everyone 's happy. We use treatment. We have better data than that because the longer you use it, the better it gets in general, but it means that people are still going to be symptomatic. So that drives home in a different painful disorder the importance of yes, treatment can be effective, but it's not the only treatment that a person is going to likely need. And so, I think that's what's so important about multidisciplinary approach. I- we may affect positive changes, reduction in pain intensity with a particular pharmacologic agent, but we don't anticipate it's like taking an antibiotic or a strep throat, not curative. And so, we want to, early on, to explain that logically, methodically, step by step. There are many options for you and we're going to, you know, systematically go through them. And I may need to call in some colleagues to help because I don't do everything. No one does everything, right? But don't feel as if there isn't any hope because there is. If we were to use intraspinal Baclofen for someone who has painful spasticity following a stroke or a spinal cord injury, combining that with physical therapy might give more effect, maybe synergistic. Some targeted muscles, some local muscles may not respond as well to the intraspinal Baclofen, so is that - what can we do? Well, we could use oral agents or we might be able to target that with botulinum toxin, and so on and so forth. So it's limitless, virtually, in what you can do. Dr Jones: There's kind of setting expectations and letting people know that you, you're going to need a lot of different approaches, right? To sort of get them the best possible outcome. Dr Argoff: Yeah, I think that's so important. And of course, no matter what we try to set out, there are going to be individuals - for those of you who are listening, we all know - who expect to be cured yesterday. That might be challenging for us not only to actually complete, but also, it's challenging for some individuals to appreciate that we're with them, we're going to work with them. It'll be a process, but we've got your back. Dr Jones: Great. And you know, this is a question that I get all the time from patients and from other clinicians is, you know, what about cannabinoids? What's the role of cannabinoids for the management of central neuropathic pain? Dr Argoff: First, I'll say that the short answer to that is we don't know. The second part of my response would be, there is new evidence that it might be helpful in the acute treatment of migraine. And I'm happy to say that the editor of this edition of Continuum is the person who developed that evidence, and it's been recently presented at the American Headache Society. But the challenge and the conundrum that we all face is, everywhere within our nervous system where there's pain being processed, there are endocannabinoid receptors. There also happen to be opioid receptors, but that's a separate issue. And the endocannabinoid system, the peripheral or central, you know, CB1, CB2, is very, very important, but we haven't figured out a way of harnessing that knowledge in developing an analgesic, an effective analgesic. And part of that is that there are so many chemical agents that have cannabinoid properties and there are different… the right balance has not yet been found. But even the legalization, the available of medical cannabis, hasn't led to a standardized approach to evaluating if a preparation does help. And that's part of the conundrum. It's like saying, ‘does medicine work?'Well, yeah, sometimes. But which medicine? Which receptor? How do you harness the right ratio between TBD, THC, other active agents, et cetera? And I think maybe as we go forward in the future, we'll be able to do that with - more precise. I mentioned Dr Schuster's study in which he had defined ratios of THC effect and CBD and was able to clearly show effect based upon that. But the average person going into a dispensary doesn't really get that. We don't get to study that. Each person's an NF1 and it's not very helpful to understand how to do that. I would say, as I'm sure you remember, there was a practice parameter that was published probably over a decade ago about using cannabis symptomatically in different neurological disorders. And I believe that it was what they studied or what they reviewed was helpful in MS-related urinary discomfort and spasticity, but not necessarily pain. Dr Jones: And we're still in the early days of studying it, right? Dr Argoff: Yes. Dr Jones: That's part of the point, as we got started late and we're still waiting for high-quality evidence. And I guess, if you look at the horizon, Dr Argoff, or the future of management of central neuropathic pain, what's going to be the next big thing? Dr Argoff: One of the joys of being asked to get involved in a project like this is that inevitably we learn so many new things because, you know, that's when anyone says, oh, you must be an expert, I say, I don't know anything because I'm always learning something new. One of the reasons why I moved to Albany Medical College about seventeen years ago was to be able to further my interest in studying why people benefit from topical analgesics by working with a scientist at Albany Med who studied keratinocyte neurochemistry and its impact on pain transmission. And that's a separate issue, but it indicates my love for the peripheral nervous system. And one of my thoughts historically, that is, what the central nervous system processes is what it processes and it might get input, as you mentioned earlier, from the peripheral nervous system, so that topical agents could be dampening central mechanisms. And lo and behold, as I was doing research for this article, I learned that people doing peripheral nerve blocks - so blocking peripheral input at the into the spinal cord - at Washington University, Simon Guterian and colleagues, demonstrate that they could give prolonged benefit from central pain by blocking peripheral input. And that's wild because certainly the nervous system is a two-way street. It's an understatement. What I really found amazing was that, again, blocking input helped the injured central nervous system to behave better. Dr Jones: That is kind of cool to think about. And I'll tell you, as editor of the journal, one of the funnest things is getting to learn all about neurology, including pain and including central neuropathic pain, when in the end you're doing all the work, I just get to sit here and enjoy it. And you're a program director of a pain fellowship. What's the pipeline look like? Are neurologists more interested in pain than they used to be? Dr Argoff: I'm happy for this. We are seeing more and more applicants from neurology into our pain management programs. I would say… I was going to say tragically. If I say tragically, it's because what specialty better understands how to diagnose, figure out, assess, come to a conclusion? You can't have pain without your brain. It's always amazed me that more neurologists weren't interested, and I understand the background and such. Just like in migraine, it's only advances in understanding mechanisms of migraine that allow neuroscientific advances that are leading to great therapeutics - that's happening and increasing in ‘pain.' Today, as program director, we had our fellowship interviews earlier today and three of the nine applicants that we interviewed were neurologists. Last week, I think we interviewed two or three also. That would not have happened five years ago or six years ago. And if you think about it, we can not only diagnose, quote-unquote figure out what's happening, but we now, with pain management training, we can offer people a variety of both invasive and noninvasive options, all while understanding what we're doing with respect to the nervous system in a way that's different than the other specialties that typically go into pain med. And that's such - for me, it's a beautiful experience and something I really enjoy doing. There isn't a neurological condition in the most part that either doesn't have pain associated with it or doesn't have mechanisms that overlap. If you think about epilepsy, and please don't think I'm crazy, but epilepsy is associated with disinhibited hyper-excitatory behavior, just to put it loosely, among certain neurons. That's what pain and neuropathic pain is about too. And you, in fact, we know that several mechanisms since now what medicines are used for both. But what was interesting since, if I may just go back to another point, one of the advances since I brought up the migraine that's very exciting is the whole story about sodium channels. Dr Harouthounian at WashU and his group used lidocaine injection. Lidocaine's a more generalized sodium channel blocker, but some of the newest treatments for treating neuropathic pain. Our NAV specific sodium channel blocker's trying to match up mechanism to treatment. Not exactly the way that we do with migraine, but still a step forward to not just generally treat but really target different neuronal mechanisms. It's an exciting time. Dr Jones: So, the pipeline is doing better because we're getting better understanding of disease, and hopefully that pulls in more interest because obviously there are big gaps in caring for patients with pain. And again, thank you, Dr Argoff, for an amazing article. Thank you for joining us and thank you for such a fascinating discussion. I enjoyed the article. I read the article, I learned from our conversation today. So, thank you for joining us to talk about central neuropathic pain. Dr Argoff: Thank you for having me. Dr Jones: Again, we've been speaking with Dr Charles Argoff, author of an article on central neuropathic pain in Continuum 's most recent issue on pain management. Please check it out, and thank you to our listeners for joining today. Dr Monteith: This is Doctor Teshamae Monteith, associate editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at Continpub.com/AudioCME. Thank you for listening to Continuum Audio.
Another press conference breakdown on tap today, we discuss the focal points of Coach's time at the podium which included questions about the poor defensive play, the tackling in particular, as well as the liability at the CB2 position and the cast of characters at that role trying to fill the void. We obviously talk about QB and more reasons why Cade isn't what we all hoped he might be, and the reason to use Brendan Sullivan more, including some verbiage from coach that may be forecasting an uptick in playing time for Sullivan. We also sprinkle in some Coach Doyle talk as well as a few solid minutes on Caitlin Clark to open the show.If you love the show and want to show support, tell your friends! And, check out our exclusive content at Patreon.com/washedupwalkons where you can find extra podcast episodes, exclusive merchandise, Merch discounts with every tier, private Walkon discord channel access, and more!Find us on social media @washedupwalkonsVisit TheWashedUpWalkons.com for all of our episodes, merchandise, and more!
The Hawks suffered an ego altering loss this weekend in East Lansing, we take a quick, concise look at what happened, and try to decipher where this team goes from here. We examine the worst Defensive performance in recent memory, talk about the tackling issues, the physicality issues, and most notably the liability we have at our CB2 spot. We try to highlight a few of the positives from this weekend in some special teams, KJ, and 3rd quarter Offensive response. And then we close with talk about Cade at QB and why we think it would be a good time to let Brendan Sullivan take control for a game. We also recap the betting weekend.If you love the show and want to show support, tell your friends! And, check out our exclusive content at Patreon.com/washedupwalkons where you can find extra podcast episodes, exclusive merchandise, Merch discounts with every tier, private Walkon discord channel access, and more!Find us on social media @washedupwalkonsVisit TheWashedUpWalkons.com for all of our episodes, merchandise, and more!
Mike Evans, Brandon Stokley, and Mark Schlereth ramble into the third hour looking at ways to get more playmakers on the Broncos to help out Bo. Stoke fires back at Cecil about the draft. Stink gives his take on a potential Broncos target and the Davante Adams situation. The guys listen to a breakdown of Palcho’s great performances and they wonder if McGlinchey will ever get his job back. All three guys gush about Riley Moss, his attitude, his competitiveness, and his quality of play as the CB2 across from PS2.
The Falcons are fresh off a huge win over the Eagles on Monday Night Football, and host Kevin Knight is joined by Dave Choate and Tre'Shon Diaz for a Q&A session with the questions provided by our Patrons and YouTube Channel Members. We talked Kirk Cousins' resurgence, Troy Andersen's development, Mike Hughes ascendance at CB2, and more. The Falcons came away with an unlikely win over the Eagles in Week 2. Atlanta's defensive did just enough and the offense came to life late against Philadelphia, with Kirk Cousins leading a 2-minute drill to take the lead and Jessie Bates III sealing the win with a pick of Jalen Hurts in the final seconds. Join host Kevin Knight and Tre'Shon Diaz for the postgame celebration! Watch the show live on Wednesdays at 8 PM ET. Support the crew on Patreon to unlock exclusive perks (and our gratitude)! Join our community Discord server!
Jennifer Fisher is a jewelry designer known for her modern take on accessories, like her popular hoop earrings. She also has a whole food life you might not know about. Between her line of seasoned salts, her popular food Instagram (@jenniferfisherkitchen), and forthcoming cookbook, Jennifer is making a name for herself in the culinary world. In this episode, host Kerry Diamond chats with Jennifer about her love of grocery stores, her CB2 collab, the influence of her father, her aversion to gatekeeping, and lessons learned running a business and raising money. Jubilee Wine Country tickets & details hereJessie Sheehan's new cookbook, Salty, Cheesy, Herby, Crispy Snackable Bakes, and tourOrder our print magazine, get show transcripts, subscribe to our newsletter, and get event details & tickets. More on Jennifer: Jennifer Fisher Jewelry, Jennifer Fisher Kitchen InstagramMore on Kerry: InstagramProduced by Catherine Baker and Elizabeth VogtEdited by Jenna SadhuContent & Partnerships Manager Londyn CrenshawRecorded at Newsstand Studios at Rockefeller CenterSpecial thanks to Good Studio in BrooklynRadio Cherry Bombe is a production of The Cherry Bombe Podcast Network.
CB2 is still a question full 747 Tue, 03 Sep 2024 17:16:23 +0000 cH5YJMKyYw8xPfKHU7KUWLPjoRUlZIKt #nfl,#kansas city chiefs,society & culture Cody & Gold #nfl,#kansas city chiefs,society & culture CB2 is still a question Hosts Cody Tapp & Alex Gold team up for 610 Sports Radio's newest mid-day show "Cody & Gold." Two born & raised Kansas Citians, Cody & Gold have been through all the highs and lows as a KC sports fan and they know the passion Kansas City has for their sports teams."Cody & Gold" will be a show focused on smart, sports conversation with the best voices from KC and around the country. It will also feature our listeners with your calls, texts & tweets as we want you to be a part of the show, not just a listener. Cody & Gold, weekdays 10a-2p on 610 Sports Radio. 2024 © 2021 Audacy, Inc. Society & Cult
Kristen Pumphrey & Thomas Neuberger are the co-owners of California-based fragrance brand, P.F. Candle Co. and authors of “At Home with Fragrance.” Now a 63-person company, P.F. Candle Co. started as a one-woman Etsy shop in 2008 out of Kristen's second bedroom. As fragrance experts, Kristen and Tom have scaled the business over the course of several years on their own with no formal business degree - DIY is at the core of everything they do. Today, products are sold in thousands of stores worldwide and their two brick and mortar stores in Los Angeles and San Francisco. Despite the company's growth, P.F. Candle Co. still proudly makes their products in-house, pouring up to 3,500 candles a day all while modernizing the craft of candle making.In This Conversation We Discuss:[00:45] Intro[01:32] From job loss to a creative business venture[02:45] Starting and finding success on Etsy[04:23] Switching platforms for cost savings[05:33] Scaling beyond Etsy artisan qualifications[06:10] Figuring out what's worth the purchase cost[07:12] Outgrowing Squarespace's limited customization[07:44] Leveraging social media to drive website traffic[09:15] Gaining online traction via retail partnerships[09:59] Episode sponsors[13:11] Managing sales mix changes during pandemic[13:56] A pro tip for women in business[14:58] From self-management to leading teams[16:49] Setting yourself apart to create business value[17:51] Finding motivation from team successes and growth[18:40] Preparing for competitive Ecommerce sales[20:20] Planning inventory for Black Friday, Cyber Monday[21:45] Evolving strategies from $1 million to $10 million[23:26] Prioritizing meaningful work over numbers[25:04] Face business challenges with creative fulfillment[26:09] Defining future goals for products and company[27:13] Get your scented soy candles at P.F. Candle Co.Resources:Subscribe to Honest Ecommerce on YoutubeFollow Kristen Pumphrey linkedin.com/in/kristenpumphrey/Follow Thomas Neuberger linkedin.com/in/thomas-neuberger-6180b5113/Book a demo today at intelligems.io/Done-for-you conversion rate optimization service storetester.com/If you're enjoying the show, we'd love it if you left Honest Ecommerce a review on Apple Podcasts. It makes a huge impact on the success of the podcast, and we love reading every one of your reviews!
Here are all the segments: Creed Humphrey extension CB2 questions Defensive Tackle questions Wanya Morris OT options The WR room Steele and LRZ
On today's episode of the Ducks Dish Podcast, ScoopDuck's Max Torres and Justin Hopkins discuss Oregon's offensive line depth amid Matthew Bedford's injury, the battle for CB2 on this year's roster, Bo Nix being named QB1 in Denver and so much more! Connect with our Oregon Ducks coverage on other platforms! Watch this episode on YouTube Subscribe to the ScoopDuck YouTube channel Follow Max Torres on Twitter Like and follow Max Torres on Facebook Follow the Ducks Dish Podcast on Twitter Learn more about your ad choices. Visit podcastchoices.com/adchoices
Jay Morrison and Dallas Robinson discuss the Bengals' joint practice against the Bears, including the fallout from injuries at running back and offensive tackle. Then, they preview the Bengals' Week 2 preseason game against the Bears. Where does the CB2 battle stand between DJ Turner and Dax Hill? Can WR Jermaine Burton earn more snaps? Who's fighting for time at EDGE and LB? All that and more on the latest episode of The PFN Bengals Podcast.
(0:00) Chris welcomes back his "work mistress"(2:55) Vikings: JJ McCarthy injury fallout, but some bright flashes from Dallas Turner.(9:20) 49ers: What's more likely...a 3-team trade, or Brandon Aiyuk stays in San Francisco?(18:20) Lions: Is Brian Branch "the next Tyrann Mathieu?"(21:45) Packers: Do they need a #1 WR to emerge?(27:40) Bears: Who will step up with Montez Sweat?(31:00) Rams: Have they hit on yet another rookie D-lineman?(33:35) Seahawks: Byron Murphy II is ready to f*** some plays up.(35:30) Buccaneers: Will we see some 2nd-year leaps?(37:50) Saints: Can they overcome their O-line woes?(40:40) Cowboys: DeMarvion Overshown flashes after a lost rookie year.(42:50) Eagles: Quinyon Mitchell is already getting praise from Vic Fangio.(46:05) Ravens: Their O-line is full of questions.(49:45) Jets: Connor weighs in on the pass rush & Haason Reddick's holdout.(57:05) Dolphins: The O-line is already struggling in preseason Week 1.(59:25) Chiefs: Who will be the CB2 across from Trent McDuffie?(1:02:20) Jaguars: Is Brian Thomas Jr. the top target in Jacksonville?
In today's episode, host Amir Farrell and co-hosts Jordan Lopez and Jordan Mackey recap Days 12 and 13 of Denver Broncos training camp and provide an update on Denver's quarterback competition. Will Bo Nix start Sunday in the preseason opener vs the Indianapolis Colts? They also discuss the emergence of rookies cornerback Kris Abrams-Draine and wide receiver Devaughn Vele. Who will win the CB2 battle and should we be concerned about Riley Moss in his second season? Socials: https://linktr.ee/broncosavenue Check out Amir's newest articles at Predominantly Orange: https://predominantlyorange.com/author/afarrellJoin our Broncos Group Chat: https://share.onbunches.com/invite/r68ex4o/mne6on5 Broncos Avenue Podcast availability: Spotify: https://open.spotify.com/show/3XlRAAh… YouTube: https://youtube.com/@BroncosAvenue?si=XqzomgpqXsSgIGqh Apple Podcasts: https://podcasts.apple.com/us/podcast… iHeart Radio: https://www.iheart.com/podcast/269-broncos-avenue-podcast-143148280/ Amazon Music: https://music.amazon.com/podcasts/f19…
As training camp comes to a close this week, Paul Calvisi, Darren Urban and Dani Sureck can only hope the weather breaks in Indianapolis next week when the Cardinals finally have outdoor practices. In the meantime, the trio talk about their top takeaways from camp - including Darius Robinson showing up, Paul's quibbles with the depth chart (and Darren disagreeing along the way), the loss of BJ Ojulari and the signing of Marquis Haynes Sr., the possibility of a splashier trade in-season if needed, L.J. Collier's rebound, joint practice fights, the QB2 battle, the CB2 battle, choices to make on the offensive line, the Indiana State Fair, and the thought of playing in Pitbull Stadium.See omnystudio.com/listener for privacy information.
Hello and welcome to Healthy Mind Healthy Life with your host Eric. This podcast is all about exploring the latest research, sharing personal stories, and providing personal tips for improving our mental health and well-being. Each episode will be joined by experts in the field of mental health, as well as individuals who have experienced the transformative power of a healthy mind firsthand. Together, we will dive into a range of topics from managing stress and anxiety to building resilience and cultivating happiness. So join us on this journey to discover new ways to take care of our minds, bodies, and souls, and let's work together to create a healthier, happier world one episode at a time. So let's get started. Hello dear listeners, welcome to Healthy Waves, the live group podcast where we dive deep into the sea of topics with the experts who bring their wealth of knowledge and insights to our discussions. I'm your host and together we will explore the nuances of the mental and the physical wellbeing and also at the same time, uncover the new perspectives and provide the practical advice to help you lead a healthier and more fulfilling life. So. But before we delve deep into the topic, because today's topic is very great, where we'll be talking about from shadows to the serenity, like harnessing the power of your mind to overcome the addiction, trauma, chronic illness, and others. So, uh, but before we do that, uh, I really love to introduce you to all of our guests. So we'll start with Dave. Dave. Maury. So, uh, the listeners, Dave, uh, lives with the bipolar disorder and is the beacon of hope and the humor for many. So as the bestselling author of the OMG That's me mental health books and stand up comic, he teaches others with the mental illness how to find humor in the darkest days. So his journey from hospitalization and homelessness, uh, to becoming a transformative figure in the mental health is nothing short of inspiring. So through his work, uh, Dave shatters the stigma, shares laughter, and offers a message of resilience and recovery. So welcome to the show, Dave. Thank you. Okay. So we'll quickly also introduce you to our, uh, next guest, Micheal Martin. So, uh, like, following a series of life changing events, Michael turned of nature and turned to nature to find that inner peace and heal himself. So after a difficult, uh, divorce, he embarked on a solo backpacking trip that led him to reconnect with the, uh, tranquility and the resilience of the natural world. So his journey of self-discovery and the emotional healing in the wilderness has given him a renewed sense of peace and the purpose which he now shares to inspire others. Also, we have, on the other hand, we have Len Len May. So he is a pioneer in the, uh, uh, medical cannabis industry and the CEO and the co-founder of Endo DNA with over 25 years of experience, Lin has shaped the legislation and culture around the cannabis, and his expertise in genomics and, um, uh, into the system has revolutionized the personalized health and the, uh, wellness. So, uh, his mission is to educate and empower the individuals through the healing powers of cannabis and the personalized medicine. So welcome to the show, Len. And, uh. Uh, Michael. Thanks for having me. Appreciate it. Lovely, lovely. So to start with, uh, I'll quickly, uh, start with Martin. Uh, so, so, uh, so, Michael, like, uh, to start with, I mean, how do you I mean, how did your solo backpacking trip to the wilderness contribute to your emotional and mental healing after, uh, uh, the phase you've been through? Uh, and what lessons did you learn during that journey? So I think overall through that journey, I rediscovered something that somebody took away from me, which was my sense of self-worth, my sense of self value. And it expanded and really took shape once I learned to embrace the idea of meditation. And once I started working that into my practice of sitting in the wilderness and learning how to befriend myself and befriend the different emotions that I was struggling with, I started to gain a sense of balance and peace and that journey. It's taught me to not only rely on the skill set that I've learned throughout life, but it's also taught me to be open to the different examples that I encounter within the living world around me. Okay. Okay. So, um. Okay. Thanks. Thanks for sharing. Uh, this. Michael. So, uh, I'll come to the, like the, like, uh, uh, so exploring the humor in the healing, uh, if you can share with us, like, how the humor became, uh, pivotal tool in your recovery journey and also, at the same time, how it can transform the lives of those with the mental illness. Um, I had a breakdown in in 1996 and from 1996 to 2010, where my last years, my dark days, uh, suffering in silence. Um, just hiding from from everyone. And then in 2010, I took a stand up comedy class for folks with mental illness, and it changed my life. Instead of, uh, me having the thought and, uh, about a past trauma and reliving that experience, I started to look for the humor in in those triggers, those things that would trigger those, those, uh, memories and, and take me to those darkest places. And once I started doing that, it again, it changed. It changed everything. I, I when the trigger happened, uh, I no longer went to those dark places. I looked for the humor in it, and, like, Lynn was talking. You know, Lynn's talking about cannabis. And I have a cannabis joke. When, uh, when cannabis was legalized in in Oregon, uh, we got a new airline. It's called Air Cannabis, and they don't charge it by how far you go, but by how high you get. So you know, it does a couple things. One, it it it, uh, made a huge difference in my life. And then I teach standup comedy to others, and I see the same transformation in them. And, you know, I'll be able to talk a little bit about that. Um, but it it also helps shatter the stigma. People, when people find out I'm bipolar, uh, you know, they tend to back away and, and actually run away as fast as they can. But by including some humor, it humanizes me. It makes it so much less scary and helps shatter the stigma. Lovely. Thank you. Thank you so much for sharing. Yeah. So I'll come to Len. Um, so after that joke. Definitely. So, uh, we'll, uh, so regarding that personalized health through the, uh, genomics, uh, if you can, if you can share, I mean, how, uh, know DNAs technology harness the power of DNA to provide that personalized, uh, health recommendations and how this can be beneficial for the individuals who are dealing with the chronic illness. Yeah. I just want to say that Dave and I got the orange memo, and I think Mike didn't get the memo, so we're, uh, we're we're very coordinated today. Uh, so, uh, I didn't check my email before this. My apologies. Yeah. I'm sorry. Uh, so I wanted to, uh, kind of take a step back and really explain to people. And I really appreciate everybody's sharing their personal journeys, because that's what it is. Uh, we are all individuals, and we all should be treated personally, individually, and not like one size fits all. Uh, medicine and wellness. That's what. That's how we treat it today. And, you know, focusing on the root cause of something instead of addressing with a pill or a shot. So I just want to say, you know, I always focused on we started with the endocannabinoid system. That was that was my goal because I was noticing I was a dispensary owner at the time, had five different dispensaries under the same brand, uh, in Southern California. And, uh, I was noticing that people would consume the same chemical variety and have a completely different experience. And the first thing I did, I focused on a plant genomics. So doing genetic sequencing in the plant, we named this plan different names, but it really doesn't mean anything. It's what the components of the plant are that you're putting in your body. So once I started realizing that, I started looking at the human genetic side and merging those two together, not defined. You know, what is the ultimate plan? It's to help people avoid or mitigate possible adverse events. So now your DNA is your personalized roadmap. So this is your human, uh, G.P.S. system. It shows you where your own personal potholes are in your road. Where is there your own personal traffic jam. So if you're aware of this, it's empowering because you can then, uh, create lifestyle, uh, modifications to be able to avoid those possible personal potholes along the way. So the way that it works is, you know, we have a it's a saliva based test you swab into your cheek or your register because we're a hippo, we're GDPR compliant. It's medical data. You send it over to our lab, we'll sequence that and genotype that and provide you a report. So like I said, uh, it's it's focusing on your endocannabinoid system first. But now we expanded the whole genome and we're providing precision, uh, wellness and precision therapeutic, uh, suggestions across the board. So we have like, uh, for women. Uh, female hormone health. So looking at predisposition and menopause. Perimenopause post menopause. Extremely helpful to women who have a predisposition to something that they can actually turn off the genetic expression by taking certain things in advance. Also, it helps their significant others because we had a lot of calls from husbands and boyfriends saying, thanks, you saved my marriage because I don't have to deal with my wife going through certain, you know, genetic challenges based on her menopause. So we have a male hormone health, we have neutral genomics or personalized supplements and, and, uh, and vitamins, etc., skin, etc., even even canine, uh, for dogs. But the concept is you book an the experience starting with DNA, giving you a suggestion, then being able to have a feedback loop on how is that working for the individual and using AI to be able to start creating predictive inferences. So the next person that comes into a healthcare professionals office, you can say, you know what, there was 100 people that were similar to your genetics that took this protocol and showed that it was efficacious, that it worked for them. And that's the way, you know, you really building personalized precision health and wellness and medicine. And, Mr. Minister, thank you for sharing this. Yeah. Yeah, yeah. That's amazing. Yeah, exactly, exactly. We talk about it. I don't want to step on anybody's toes because you're moderating this. But you talk about, you know, addiction. You talk about mental health and all of these things. Well, I just want to make a couple of statements. Number one, there's a very large percentage of human beings that have a treatment resistant gene. So we have these, uh, you know, antidepressant, anti-anxiety medications. We go to a psycho pharmacologist. They look at us, they diagnosis, and they say, all right, here's your medication, here's your SSRI, etc. well, guess what? Maybe close to 30% of the population has a predisposition to treatment resistance. So they're going to get their pill. It's not going to work for them but they'll get all the side effects from that. So why are we not making that standard practice to be able to do that? Additionally, you know, we work with a lot of pain management specialists, and, uh, there's one quarter of the population has a predisposition to opioid, uh, dependence. So we're giving people opioids without understanding that by giving them the opioid, you can actually turn on the expression of the genetic predisposition and get them to be dependent. Not everybody. But if there's four of us on this, if we all take an oxy. One of us may actually get triggered that, uh, that dependence gene. So these are the things that we have to be extremely aware of as, as us, as patients or as humans and working with our health care professionals. It has to be a more of a collaborative kind of approach to health and wellness, I understand. Yeah. Thank you. Thank you for shooting. Yeah. So, uh, I'll come to, uh, Michael again. So, uh, for the power of solitude, if you can describe the impact of it. And, uh, also like disconnecting from the stress of the everyday life, uh, on your mental health. So, uh, if you can share and also, like, how can others incorporate this into their own lives? So when you bring up the word disconnection, I have a very, very strong relationship with that word because it's a trait that I have, and I really rely on the idea of disconnecting and it brought me into the wilderness is something we all do. Now, a part of that that we all face is like the fear of sitting alone with ourselves. We bring the mindful aspect of that out here with you. It almost makes it a little bit more comfortable because you're relying on the power of observation, which is something that we all utilize in our everyday life. And you're able to observe the animals, plants, trees and the way that they move and what it does for me and what I like to point out, the people that I work with is it gives you an opportunity to step away from that story of self suffering that we all tell ourselves that we all caught up in, because it's easy and just watch the environment, watch how things move and how they interact with each other. You can build a new story around which team to correct the story that's holding you back. So it helps you to bring this ability to sit with yourself and connect emotionally and inside while engaging the living world around you and removing that disconnect to build a new narrative and a new story that helps you to get and achieve the goals in it. You know, I think it really builds on the clinical aspect of things, because we essentially work hand in hand and whether we're in the clinical. From the outdoor side. We're still working with that collaborative property, you know, vibrating with the person that's guiding us one or the other or the environment around us. But it all comes back to the fact that we got to believe. We got to believe that the steps and the effort that we're putting into whatever avenue we're pursuing is going to achieve that goal. You know, we talk about the medications and this and that. Well, if we rely fully on somebody to give us an answer, it's not going to be a long term fix. So by bringing these mindful practices in to a nature background, you know, peaceful tranquility setting like this. You're able to speak and listen to that voice of hope inside of you. Okay. Got it. Understood. So, um. Okay, I'll come to Dave. Uh, like, what was the turning point that shifted your control over the bipolar disorder? And, uh, how do you guide others to find their own moments of the transformation through the stand up comedy? For me. You know, manic depression, bipolar disorder is cyclical. So I would go into depressive episodes. And as I got older, the depression, the episodes got deeper and deeper, darker and darker and lasted longer. And the same thing with the mania. It it it, uh, I the fly among the clouds, I'd get higher. I had to think I was the smartest person in the room. And, uh, you know, uh, oftentimes I was I was an asshole. Uh, without planning it, without knowing it. It's just how it came out. And so, uh, through I think what I hear, too, from from Lana and Mike is, you know, for me, taking quiet time, I don't necessarily call a meditation. uh, because meditation for me means I've got to get somewhere to, uh, that quiet place where I really don't have any thoughts or they're minimal. And with bipolar disorder, the anxiety is constant and it's always there. And our minds are racing and loops of negative thoughts that are constant. And so the quiet time gave some reprieve for that. And what would happen would be the things that were important would just bubble up in my head. And I knew, you know, maybe it's two things or three things. Um, but oftentimes, um. One thing. If I could accomplish one thing, um, that was success. And I found I was making lists of, uh, lists of things to do, the things that I wanted to do, things that needed to be done. And I could, uh, it was overwhelming and, uh, created anxiety and worse than the depression or the mania. And when I started making lists of one thing or two things or three things, then I could have success by doing just that one thing, and I could mark it off my list and feel good about it. And then that encouraged me to do the other. As far as a turning point, um, part of it was writing my blogging. I blog for BP, hope.com, and my blog posts have been read by over a million people, and the most comment common comment from them was OMG that's me, you're telling my story and I was writing it. When I was writing it, I was actually telling my story and I was helping other people, but I was also helping myself and and I could see it. So the combination of that and then being able to start looking for the humor in my experiences and, uh. You know those? Those were the things that that started me in a different direction. Also, I've got to say medication helped the medication. You know, you don't you don't, uh, you get cured from having bipolar disorder or depression or anxiety, but the medications I'm making can make it so the the lows aren't quite so low and they don't last quite so long. And the, the high is don't go quite so high and they don't last too long. Uh, but again the anxiety was the worst. And you know, just getting out of my own head, whatever, you know, I was stuck. We were stuck. When we're doing that in our own heads, and we have senses of dread and senses of guilt, and it's just constant. So being able to get out of my head, uh, was just and it was, it was just a little bit at a time, but it was a blessing and helped turn, start to turn things around for me. Um. Sort of minister. So can I jump in there real quick to something that was very important to me. It was the assumption of meditation that you had. You know, it was always had to go somewhere. When I got into meditation, I had the same kind of view as caught in the stigmas of it. Like, you know, you got to shave your head. You got one of those 1998, uh, chant CDs or whatever the case may be. I had to talk therapy session where it was introduced to me. I thought it just like that. Just like you were talking about. And then I went out back and I picked up my crossbow and I started shooting, and I realized that all the different things in meditation that are important the breathing, the slowing your thoughts down to being able to center yourself were a part of my my enjoyment, my shooting. So then I started to be able to transition that into coming out in the wilderness. But what I'm looking at is the fact that we all, in one form or another, have, within our daily processes and our daily routines, some form of meditation, which it doesn't necessarily have to go to a certain spot or a certain destination. It's about the journey, the thought process, just like you were talking about writing things down, how you work through them. That's the that's essentially what meditation is about. It's not about chasing a thought or a direction or even technically sitting still. Nine times out of ten, when I'm out in the wilderness with a group, we're walking. We're focusing on walking meditation. It's simply about channeling your thoughts and being able to look at them, to slow down and bring yourself back into the present moment so that everything else is beating down on you. All that stress disorder and, you know, just disruptions are not what you're focused on. You're focusing on you and how you can overcome each of those. And. It's a staircase essentially in front of you to climb and reach each one of those objectives that you write down on the paper. Yeah. And if I may, I like what you said. And if I sit down and I'm going to meditate and I have a purpose for that, I'm going to work on this aspect of what's going on in my life. It doesn't work when I sit down and just be Then again, uh, I calm and the thoughts bubble up, and then that's that's where I end up at it. Not. Not trying to get somewhere, just allowing my mind to to, uh, help me discover, uh, a pathway. Uh, you know, it's right for me. Absolutely. There's always a unique pathway and a unique, you know, individualized journey. If I was to make any suggestion as to, you know, help you kind of tame that or change that in a different direction at some point, if you were comfortable with it would be the idea of walking meditation. Just simply go out for a walk and kind of focusing on inside of your breathing and setting up the actual movements that you're making, the way that it feels when your foot is the ground, the way. You feel the push against you, or it's within your arms and things like that. And ultimately it aimed at kind of softening all that tension that you're bringing to the table when you try to sit down. Because to me, I get a feeling that there's a lot of the hamster wheel momentum going on within the thought process, and your hand is your outlet in writing it down. If you added another tool into it by being in this walking meditation, I feel like it may kind of summarize things for you a little bit and kind of help you to ease into some of these ideas that we're trying to work through. Thanks for that. Well, it's definitely. A great. So, uh, it is a great discussion, I would say. And also I'll quickly come to Len. Uh, so, uh, so, Len, like what? According to you, I mean, uh, I do the, uh, uh, cannabinoids and, uh, interact with the, uh, uh, endocannabinoid system. Like, what role do they play in managing the mental health and the wellness? Um. I'm going to try to see if I can integrate the answer with some of the things that both, uh, Dave, Mike said, uh, when I was a kid, I was, uh, I would sit in class and the teacher would call my brain. I would have different thoughts. Uh, so it was the daydreaming kind of kid. And at some point I was diagnosed with the attention deficit disorder, which I never thought it was a disorder. I always thought it was my superpower, but they labeled it a disorder. So, as Dave said, you know, for some people, medication works. For other people, it doesn't work as well. You got to find the right one. So I was put on prescription medication. I can't say it didn't work. The goal of it was to help me focus, which it did, but it removed my connection to self. So I had no connection to my emotional sense. And uh, by meeting some older kids, they asked me if I wanted to smoke a cigarette. They actually try to, uh, you know, fool me and put cannabis in the cigarette. So I had an experience with cannabis. I went back to class and the windows are open in my head, narrowed, and I could focus. I never said anything to anybody because cannabis wasn't really supposed to be medicine. It's a drug, you know, uh, at that time. But for me, it became my medicine. So I got off the prescription medications. And I'm not advocating this for anybody. This is my experience. And, uh, you know, and I can relate to what Dave was saying about, you know, your mind is trying to escape in many different things. There's all these thoughts because I have this ad and, uh, you know, meditation for me. I want to take so many different classes. I took transcendental Meditation, all those things. But as Mike was saying, the best time that I quote unquote meditate is when I hike in nature. Stop thinking and I just be. And all those kind of things, uh, start flowing in and your your mind gets clarity. You become a vessel for things to start downloading to you. And now your ideas are much more clear. So there's different ways to meditate. I agree with Mike and nature's huge help with that. But so to go back to answer your question about mental health and anxiety and all that stuff, I think it's important for us to establish what the endocannabinoid system really is and how it works, and then how cannabis sort of interacts with that. We discovered this system in 1992. It's it wasn't that long ago, uh, and it evolved with us. There's a lot of things in our bodies that, you know, through evolution, we no longer use and need. But this system evolved with us. So the main goal of the endocannabinoid system is to maintain balance or homeostasis. The way that it does this, it gets signals from the other systems. So like your immune system, your endocrine system, etc., it sends up the central nervous system, sort of like salmon swimming upstream to your brain. And your brain makes a decision which neurochemicals to be able to secrete to get that system back in balance. So the two that are endogenous means we create those ourselves. Uh, part of the endocannabinoid system are called anandamide. And the word and the second one is two AG. So the word uh, Ananda means bliss and Sanskrit is your bliss. Uh, molecule. This is what secreted. This is when we when we run, uh, we get the runner's high. This is one of the chemicals that we produce that gets, uh, made. So when we consume cannabis, the main the two main cannabinoids. Phyto cannabis means the plant is delivering that. Uh, it's called THC delta nine, THC, uh, or and CBD, cannabidiol CBD. So when the plant grows, uh, and you remove that, uh, that bud from plant, it has an acid molecule to it when you heat it. Uh, it's called decrease oscillation. It drops the acid molecule and it binds to our receptors there in our body. So we have CB1 receptors. They're mostly located in our brain and central nervous system. When we consume THC, it binds to your CB1 receptor and releases anandamide. So that's the way the drug works. When we, uh, consume CBD, it has an affinity for the CB2 receptors, which are mostly located in our immune or digestive system or body, and it releases to AG. So those are the two chemicals, neurochemicals that are released that a lion which is cannabis, uh, helps to secrete. Now going back and answering your question about mental health, etc., so let's say. I'll use Mike as an example, but he seems to be a guy that doesn't get rattled really fast, but I'll use him as an example anyway. So Mike is walking down the street and a car flies out of almost nowhere and almost hits him and he's going to have a fight or flight experience. So some of the things are going to happen is you're going to have a secretion of, uh, neurochemicals dopamine, adrenaline, norepinephrine, cortisol. Now, when he realizes his mind realizes it's safe, there's no line chasing you in the jungle. There's two things that happen. There's the reuptake of those neurochemicals, and then your brain releases new neurochemicals to get you back to balance and homeostasis. And those are anandamide and to AG. So your genetics how they would play a role in that. Let's say that Mike has a predisposition to, uh, stress reactivity. And I know that Dave does this. Why? I want to use him as an example, because he already is diagnosed. Let's say he has a predisposition of stress reactivity. It's a gene called, uh, FH five fatty acid amide hydrolase. Very, very important gene. But we may not know because it breaks down anandamide which is that endogenous endocannabinoids. So if he's breaking down anandamide at a very rapid pace compared to the average person, that cortisol that's in his bloodstream can stay longer. And if the cortisol is staying longer in his bloodstream, there's several things that can happen. Number one, it can lower his pH level, make him more acidic. Your immune system can then over respond to that and create inflammation. So what you may feel is inflammation in your knees anywhere in your joints, knees, hips, elbows, neck, back, etc. if he has predisposition to gut health issues, it can actually turn on the expression of IBD or other gut health challenges. The good news is, by understanding this, you can subsidize what you're naturally deficient in. So maybe take some THC, it'll bind to that receptor and I'll actually squirt more anandamide. On the flip side, if you take a little bit too much THC, it does the opposite. It can actually trigger the stress reactivity, make people feel more anxious. And then if he has a gene for PTSD now can replay that over and over and over. And instead of having a therapeutic benefit, you're actually creating an adverse event. So being able to know this about yourself and take the right amount. So a suggestion would be maybe take higher CBD, less THC. And then to answer your other question. Terpenes are essential oils that the plants produce. Every plant produces essential oils in nature. In cannabis, there's two things. The terpenes give it its smell and also have an effect. So if you're prone to stress reactivity, you may want to turn in profile first. That is calming. So something like Lidl, which is also found in lavender, is a common terpene. The second 1st May be beta carotene, which is found in clove and black pepper, and also in some cannabis varieties, and that is an anti-inflammatory. Works very well with CBD to reduce inflammation. So as you're using THC as an example to reduce the pain, you have your your sort of formulation that is geared directly to you. And then you can find the products that are more identified to you. And two other things really, really quick. This one is metabolic function of dosing. How you dose anything is really important because how you metabolize things are different. The doctor tells you to take two of these. Well why am I taking two? Why am I not taking four? Why is Mike not taking one? He may be a slow metabolism, so understanding how to dose correctly is really important. And the last thing is interactions. So we're taking phyto cannabinoids and we're also taking an SSRI like Davis taking medication. There could be an interaction because at that medication uses the same enzymatic pathway one that can be an inducer, one can be an inhibitor. So you got to look at all these different things to be able to guide people to more personalized experience with anything in especially, you know, uh, fighter cannabinoids like, uh, you know, THC and CBD. Wow. Great way of, uh, explaining. Yeah. Thank you. Thank you so much. And it's really, uh, really helpful. Yeah, sure. So, uh, uh, before, I mean, before we wrap. So I'll quickly introduce, I mean, not introduce, I mean, quickly, uh, I want to ask, uh, one advice for the listeners. Uh, what would it be? So anyone, anyone want to start? Um. I'll start. I think, uh, a couple things is when we are in that anxiety state or that depressive state, we, we, you know, we we're we're oftentimes unable to move or do things and, and go out and interact with people. And uh, I know for me, when that was happening, I, um, I ended up going to the mailbox at night, so I didn't see anybody. Um, but I, I think seeing. You know, and knowing that that these things are going on and having a plan for if we're going to be out and interacting with people, have a plan for, um, what are some topics to talk about? And also to, to make sure that we don't just vomit everything about our personal self that, uh, is, you know, it's important to us and that's what's happening with us. But it's it's it's outputting to somebody else. So, uh, there's two things. Uh, uh, smile, ask and listen. And when we smile and say in our mind that about the person we're talking to, if we say, I love you or I like you, our eyes brighten and a smile comes to our face. And then we ask a question and listen carefully. And, uh uh, that makes a huge difference. And then the other one is an acronym that that I talk to, the folks I work with, with mental illness. And the acronym is wait, wait. And it stands for why am I talking? And knowing why you're talking is good. Because usually oftentimes when we're talking, we're we're talking about ourselves. And once we're talking about ourselves, we're still in our head. We're seeking we're seeking acceptance. We're we're trying, you know, we're trying to be okay and show people or take care. We're pretending. And, um, um, you know, we don't have to pretend if we smile, ask and listen. And if we have an idea when we're going into an event, some of the questions we're going to be asking and we're prepared, then that helps us, uh, you know, again, get a get out of our head and, uh, be aware of the surroundings. And, uh, people like to talk about themselves. So the more we ask and the more we listen, the more people like us, uh, we can go home And we. Instead of saying, I wish I hadn't said that, I'm embarrassed about saying this. Uh, we can go home feeling good that we talk to somebody, we learn from somebody. And, um, you know, that gives us peace of mind. And peace of mind is everything when you're living with, uh, depression, anxiety and mania. Uh, peace of mind is is everything, whether it be whether you get it from walking, meditation or, um, one of my favorite things to do is go to Oregon wine country and sit on the deck and overlook the vineyards and have a small glass of wine. And my mind just, you know, just goes and it's it's it's amazing. Lovely. Great. Thank you. Uh, so, Mike, you want to share? So I think actually I would probably start by raising a very, very valid question that comes to mind. Why are we repressing or fighting who we are and starting to embrace, befriend and grow the experience of who we are? Because, you know, I've come from much different backgrounds, but all three of us are on the exact same mission. What makes that mission look and feel and sound different? The labels and the terminology. If any one of us connected on the street somewhere and we started up conversation, that conversation would flow great. But because we're in this arena right now, we're having these little bit of hiccups back and forth because the stigmas, they are what we stick that fear behind. So if we take time to not only learn about ourselves and embrace their selves, find their voice. And then open our ears and allow for next to us to do this. And we would answer so many more questions, so much quicker, and we would provide so much great help for the people that we're trying to serve. Because I've seen ideas, I've heard points and thoughts in this conversation that I've never thought of from that perspective. But now when I take back and apply them to the story I have sends up a new door. You know, I'm sitting here at a campfire right now sharing stories and ideas that may sound completely different to somebody else, but when they apply them to their to the context of the world they live, it still provides it the same motivation. And I think whether it's in the arena of trying to help someone or just to own personal lives, removing those layers, realizing that we all have a place within the circle, that even is the step that needs to be taken. Okay. Okay. So, Len. Well, I have to agree with my colleagues on here. And Mike said something really profound. Knowing yourself is key. And 99.9% of our genetics is the same. We are all the same. It's that 0.1% that really makes us different. And once we understand those nuances, we can connect with love and kindness with our fellow human on a path that is similar. Instead of focusing on that 0.1%, that makes us different when we're looking to treat ourselves health and wellness wise. We have to understand that that 0.1% nuance is also what can make us different in terms of treatment. So we're not going to be treated exactly the same way all the time with our health and wellness, whether it's mental or physical health. So the thing that I want to express to people is really learn yourself as much as possible, do as much diagnostic work on yourself as possible. Look at your genetics. Look at your epigenetic expression. Look at your gut microbiome. Understand all these things and then actually treat yourself first with love and kindness. Understand that you may have these predispositions, but you are empowered to actually make lifestyle changes according to that. And it's not a sentence. Just because you have something genetically predisposed to it doesn't mean that you're not empowered to make changes. But the more you learn about yourself, the better you can collaborate with people, your health care professionals and yourself. Love and kindness. Exactly, exactly. Lovely. Great, great. Thank you. Thank you so much, everyone, for joining us on this episode of Healthy Waves. And I hope that the listeners, like our discussions today, have provided you with the valuable insights and the inspiration to harness the power, um, of your mind in overcoming the addiction, trauma, chronic illness. So, uh, and definitely a huge, uh, thank you to our amazing guests. Uh, they've Mike Len, uh, for sharing, um, uh, their stories and the expertise with us and for the listeners, I would love to mention, like always remember that, uh, no matter how the turf journey is, there is always a hope. And, uh, there is a way to find light in the darkness. So stay tuned, uh, for more expert discussions on our next episode. And until then, take care and stay healthy. So thank you so much. Thank you. Thank you. Great.
Sheil is joined by Brandon Lee Gowton of Bleeding Green Nation who was at Eagles training camp on Tuesday and made some astute observations about what he's seen so far. Will 2023 first-round pick Nolan Smith make an impact this year based off of what he's done at camp so far (13:04)? How different has the offense looked under Kellen Moore in training camp (30:54)? Will 2024 first-round pick Quinyon Mitchell be receiving a lot of snaps at CB2 this season with how good he's been at camp (39:05)? Plus, is Jalen Carter underrated (46:01)? We want to hear from you! 215-315-7982 The Ringer is committed to responsible gaming. Please check out rg-help.com to find out more, or listen to the end of the episode for additional details. Host: Sheil Kapadia Guest: Brandon Lee Gowton Producer: Cliff Augustin Music Composed By: Teddy Grossman and Jackson Greenberg Learn more about your ad choices. Visit podcastchoices.com/adchoices
Michael Wilson and rookie WR Marvin Harrison Jr. put on a show as the Arizona Cardinals continued training camp at State Farm Stadium. Does rookie Max Melton have the edge over Garrett Williams as CB2? Will Tip Reiman make an impact on offense? Is Cards QB Kyler Murray poised for a career year under HC Jonathan Gannon? Join Johnny Venerable, Bo Back and Damon Dawg on Thursday's PHNX Cardinals podcast! 0:00 Intro 25:00 Hjalte Froholdt gearing up for year 2 in Arizona 53:30 Thoughts on cornerback group 59:50 QB2 competition An ALLCITY Network Production SUBSCRIBE to our YouTube: https://bit.ly/phnx_youtube ALL THINGS PHNX: http://linktr.ee/phnxsports PHNX Events: Get your tickets to PHNX events and takeovers here: https://gophnx.com/events/ bet365: https://www.bet365.com/olp/open-account?affiliate=365_03330244 Use the code PHNX365 to sign up, deposit $10 and choose between either: Bet and Get offer and place a bet of $5 or more and get $150 in Bonus Bets OR First Bet Safety Net offer by placing a bet up to $1000 and if your qualifying bet loses you receive a matched refund in Bonus bets Disclaimer: Must be 21+ and physically located in AZ. If you or someone you know has a gambling problem and wants help, call 1-800-NEXT-STEP, text NEXTSTEP to 53342 or visit https://problemgambling.az.gov/ Indeed: listeners of this show will get a $75 SPONSORED JOB CREDIT to get your jobs more visibility at https://indeed.com/allcity. Terms and conditions apply. Need to hire? You need Indeed. Desert Financial Credit Union: Open a free checking account online with Desert Financial Credit Union and get an Arizona Cardinals VISA ® Debit Card https://www.desertfinancial.com/cardinals Gametime: Download the Gametime app, create an account, and use code PHNX for $20 off your first purchase. Terms apply. Circle K: Join Inner Circle for free by downloading the Circle K app today! Head to https://www.circlek.com/store-locator to find Circle Ks near you! Four Peaks: Follow them on social @fourpeaksbrew & @fourpeakspub! Must be 21+. Enjoy responsibly. Shady Rays: Exclusively for our listeners, Shady Rays is giving out their best deal of the season. Head to https://shadyrays.com and use code: PHNX for 35% off polarized sunglasses. Try for yourself the shades rated 5 stars by over 300,000 people. TrueFan Travel: For PHNX Cardinals Road Trip to Miami, Head to https://truefantravel.com/trips/ to book your spot today! Chicken N Pickle: Head to https://chickennpickle.com to see all the fun you can have at their Glendale location! PHNX will be hosting Trivia Nights and Pickleball Tournaments so stay tuned for info! When you shop through links in the description, we may earn affiliate commissions. Copyright Disclaimer under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In our final episode of Season 8 we welcome Janet Hayes, CEO of Crate and Barrel Holdings, the leading home furnishings player with over 100 stores in 9 countries.Janet shares leadership lessons from a remarkable career with brands like Williams-Sonoma, Pottery Barn, Nike, and Gap and, now, in her current role driving growth at the owner of Crate & Barrel, CB2, and Hudson Grace. We delve into her perspectives on the role of technology, the changing nature of work in a post-COVID world, and more. We also get a glimpse into the drive forces behind their new flagship store in New York's Flatiron District. But before our fantastic interview we unpack the week in retail news, starting with Amazon achieving another remarkable milestone, along with word of its pending launch of a Temu/Shein fighter. Then we try to make sense of just what the heck is going on at Walgreen's before dipping into less than stellar earnings news from Nike and JC Penney. We wrap up with what seem like forever troubles at Forever 21. About JanetJanet Hayes is a retail industry veteran, with more than 30 years of leadership experience building digitally-led and customer-centric organizations. Currently, Janet is CEO of Crate and Barrel Holdings, a role she started in August 2020, amidst a global pandemic that catalyzed a pivotal shift in consumers' lives and the retail industry as a whole.Focused on building modern, authentic brands, Janet maximizes growth and profitability by elevating the customer experience through an omnichannel and personalized brand presence.A modern mindset guides Janet's leadership style and centers around making decisions rooted in personal purpose. Janet is an inspiring, inclusive leader who builds, mentors, and leads high performing teams that reflect CBH customers' unique values and experiences.www.crateandbarrel.comApp: Download the new Crate & Barrel App: https://apps.apple.com/us/app/crate-barrel/id529356019 About UsSteve Dennis is a strategic advisor, board member, and keynote speaker focused on strategic growth and transformation and the impact of digital disruption. He is the author of the bestselling book Remarkable Retail: How To Win & Keep Customers in the Age of Disruption and the all new Leaders Leap: Transforming Your Company at the Speed of Disruption , now available for purchase in the U.S. and available for pre-order at book retailers elsewhere. Steve regularly shares his insights in his role as a Forbes senior contributor and on social media..Don't forget to join Steve's new Linked Group for his new book.Michael LeBlanc is the president and founder of M.E. LeBlanc & Company Inc, a senior retail advisor, keynote speaker and media entrepreneur. He has been on the front lines of retail industry change for his entire career. He has delivered keynotes, hosted fire-side discussions and participated worldwide in thought leadership panels, most recently on the main stage in Toronto at Retail Council of Canada's Retail Secure conference with leaders from The Gap and Kroger talking about violence in retail stores, keynotes on the state & future of retail in Orlando and Halifax, and at the 2023 Canadian GroceryConnex conference, hosting the CEOs of Walmart Canada, Longo's and Save-On-Foods Canada. Michael brings 25+ years of brand/retail/marketing & eCommerce leadership experience with Levi's, Black & Decker, Hudson's Bay, Pandora Jewellery, The Shopping Channel and Retail Council of Canada to his advisory, speaking and media practice. Michael also produces and hosts a network of leading retail trade podcasts, including the award-winning No.1 independent retail industry podcast in North America, Remarkable Retail,Canada's top retail industry podcast; the Voice of Retail; Canada's top food industry and the top Canadian-produced management independent podcasts in the country, The Food Professor, with Dr. Sylvain Charlebois. Rethink Retail has recognized Michael as one of the top global retail influencers for the fourth year in a row, Coresight Research has named Michael a Retail AI Influencer, and you can tune into Michael's cooking show, Last Request BBQ, on YouTube, Instagram, X and yes, TikTok. Available for keynote presentations helping retailers, brands and retail industry insiders explaining the current state of the retail industry in Canada and the U.S., and the future of retail.
Matt continues his series on the impact of cannabis, THC, and CBD upon sleep this week with an examination into the intricacies of cannabidiol (CBD), which, unlike its psychoactive counterpart THC, does not induce a high but is recognized for its potential therapeutic effects. While studies suggest that CBD may aid in alleviating anxiety, movement disorders, pain, and addiction, in this episode, our host focuses on exploring CBD's potential influence on sleep quality while examining its biochemistry and neurobiology.Matt explains that CBD modulates the body's endocannabinoid system without directly binding to cannabinoid receptors like CB1 and CB2, which THC targets. Instead, CBD enhances the activity of natural endocannabinoids, extending their effectiveness. This modulation can promote sleep by increasing deep non-REM sleep, as demonstrated in both animal and human studies. Despite these promising results, Matt emphasizes that the effects of CBD on sleep are complex and dose-dependent, with higher doses showing potential benefits. Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.Are sleep troubles keeping you up at night? Matt used to be a skeptic about meditation, but 7 years ago, he tried it using a fantastic meditation app called ‘Calm', and it transformed his sleep! Now, he meditates for 10 minutes before bedtime every night! He's also partnered with Calm who have been generous enough to offer his podcast listeners an exclusive 40% discount on their premium subscription! All you have to do is go to calm.com/mattwalker and take advantage of this incredible deal! Head on over now and improve your sleep today!The good people at InsideTracker are one of the sponsors of this week's episode, and they are generously offering a special 25% off any one of their programs for anyone who uses the above link during the time window of this episode. InsideTracker is a personalized biometric platform that analyzes your blood and your DNA to better understand what's happening inside of you.Another exciting sponsor is Levels, the groundbreaking continuous glucose monitor that keeps track of your blood sugar levels day and night. Whether you're curious about your body's response to different foods or seeking to enhance your sleep quality, Levels has the answers. If you're interested, visit levels.link/Mattwalker now to grab an exclusive podcast offer of two free months of this impactful service, and take charge of your health journey today!As always, if you have thoughts or feedback you'd like to share, please reach out to Matt on Instagram.
1 hour and 49 minutes The Sponsors Thank you to Underground Printing for making this all possible. Rishi and Ryan have been our biggest supporters from the beginning. Check out their wide selection of officially licensed Michigan fan gear at their 3 store locations in Ann Arbor or learn about their custom apparel business at undergroundshirts.com. Our associate sponsors are: Peak Wealth Management, Matt Demorest - Realtor and Lender, Ann Arbor Elder Law, Michigan Law Grad, Human Element, Sharon's Heating & Air Conditioning, Venue by 4M where we recorded this, The Nose Bleeds, which is the Sklars Bros' reboot of Cheap Seats on UFC Fight Pass, Autograph: Fandom Rewarded, who just launched an app where you earn rewards for things like reading MGoBlog and listening to this podcast, and introducing Champions Circle, the NIL fund keeping our team together. 1. Basketball Bits Starts at 1:00 Seth is once again the biggest dork. Will Tschetter is returning, Terrance Williams II hit the portal and declared for the NBA draft (¯_(ツ)_/¯), and Dusty May has made some assistant coaching hires. Mike Boynton and Akeem Miskdeen have joined the staff. These moves seem like they're recruiting focused. All three of the big three from FAU are in the portal, Nick Boyd released a big list of schools that did not have Michigan on it. Michigan should get Davis and Goldin. Have you met Louisville's fanbase? What about the rest of Michigan's roster? Brian gives his guess on 10-11 roster spots. 2. Football Spring Bits - Defense Starts at 38:36 As it turns out, the defense is better than the offense right now. They're really high on Jaishawn Barham, the linebacker transfer from Maryland. Rolder is still dinged up and we don't blame him for what happened against Ohio State. There is speculation on the CB2 chatter and why it's more encouraging than this time last year. LB2 and CB2 should be fine. On the defensive line, TJ Guy is a guy (ahhh he did it). Etta is also encouraging. It won't be last team's defensive line but it should be a two deep we're comfortable with. The last two questions are “what do we do without Rod Moore” and “who is the nickel back”? 3. Football Spring Bits - Offense Starts at 50:20 Takes hotter than our Kickstarter. On offense, it feels like Alex Orji is simply the leader at quarterback so far. To be fair, the offensive line is probably having a bad time against this defensive line. Semaj Morgan has been getting talked up which is not surprising. Donovan Edwards has apparently gained 15 pounds (with no mention of him catching passes). Marlin Klein is being called the best athlete of the tight ends. Not really any surprises along the offensive line. Sure, some of the problems at quarterback could be the defensive line dominating the offense line but those talks could also be covering up limitations of the quarterbacks. It could all work out but for that to happen you have to run the Denard offense and win some Iowa games. What would you consider a successful season this year? 4. NCAA Hockey Tournament Starts at 1:19:48 Michigan hockey reaches the frozen four for the third consecutive year. Michigan scores three in the 3rd period after North Dakota was arguably the better team in the first two periods. This is the opposite of what the season narrative has been. Of teams that have made the frozen four historically, the numbers one, two, three, and six are in. This is the bluest of blue bloods frozen four. Denver is 100 duck sized horses. Boston College has snipers, can't get into a shooting match with them. MUSIC: "Miracles" — Alex G “Time Waits For No One" — The Rolling Stones “Will I See You Again”— Three Sacred Souls “Across 110th Street”
Today, I am blessed to have here with me Dr Lee Know. He is a licensed naturopathic doctor and Cannanda's co-founder and Managing Director. This company manufactures Natural Health Products to assist people and animals in living long and happy lives. Dr Lee has always been interested in health and medicine. He thought that, just like others, he would go to a conventional medical school. However, he truly desires to study nutrition, botanical medicine, and all other types of traditional medicine. The problem is that he doesn't know the path towards it. Moving forward, Dr Lee met a person who introduced him the naturopathic medicine. Since then, he has continued to study the field of medicine he is interested in. Dr Lee Know is also the author of Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself. This book dives deeper into the scientific understanding of what mitochondria is and how it affects medicine in the future. In this episode, Dr Lee discusses how mitochondria and the ketogenic diet are linked. He also shares tips on how to take care of our mitochondria. Dr. Lee shares his journey in building his company, Cannanda. Aside from that, he talks about what Endocannabinoid System is. Furthermore, Dr Lee tells the difference between THC and CBD and how to ease a dog's anxiety using one of their top-selling products. Tune in as we chat about the mitochondria, ketogenic diet, endocannabinoid system, cannabis, and his company, Cannanda. Get Cannanda products here (coupon code applied) https://www.cannanda.com/KETOKAMP Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E S P ON S O R S ⭐ Bioptimizers Magnesium Breakthrough. Get the best night of sleep ever. NO OTHER supplement on the market offers 7 types of magnesium in 1 bottle. Visit bioptimizers.com/ketokamp and use promo code ketokamp10 for 10% off your first order. ⭐ Upgraded Formulas | http://www.upgradedformulas.com Purchase Upgraded Formulas, Charge Electrolytes, and other products. GET 15% OFF with Coupon Code: KETOSIS Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [8:30] How Does Mitochondria and Ketogenic Diet Relate To Each Other? Mitochondria is very heavily involved in the ketogenic diet, or the benefits of the ketogenic diet really heavily weigh on the mitochondria. There is a strong link between the benefits of the ketogenic diet and how it improves the functioning of the mitochondria. There are incredible success stories of people with Alzheimer's improving their condition by going on a ketogenic diet. Studies on the ketogenic diet and calorie restriction found that you can reverse type two diabetes. [18:15] Are Worried About Your Mitochondria? Get Physically Active and Take Care of It! A sedentary lifestyle has a huge negative impact on the mitochondria Being physically active is the greatest thing you can do for your mitochondria. You need to ensure that you feed your body with the nutrients it needs, but not in the way you introduce excessive calories. The more mitochondria you have, the better everything else works. [27:46] Dr Lee's Excellent Journey in Building His Company, Cannanda Dr Lee has always been interested in studying the Endocannabinoid system's influence on health. The endocannabinoid system and the mitochondria are both related to homeostasis. Anytime something goes wrong in the body, the endocannabinoid system's job is to jump into action and start the processes needed to bring about healing or bring those processes back towards their balanced state. Medicinal use of cannabis was legalized in Canada, which allowed him to study more, and grew his interest in this field. Dr Lee realizes the need to create a more accessible and economical business for customers to buy. [33:53] How to Activate Endocannabinoid System to Regulate Our Nervous System? The two main components of the Endocannabinoid System are the cannabinoid compounds that our bodies make and the cannabinoid receptors. Cannabinoid receptors have two main types that are often talked about, and that is cannabinoid receptor type one or CB1, and cannabinoid receptor type two or CB2. When you use cannabis and THC, that activates the CB1 receptors, and that's what gets people high. CB2 brings a lot of health benefits when activated. The difference in CB1 is that you won't be intoxicated. The Endocannabinoid system regulates the nervous system by sending inhibitory signals up the chain. [41:05] THC and CBD: What Is Their Difference and How It Affects The Benefits You Could Get? CBD actually doesn't activate CB1 or CB2 receptors. Unlike THC, which can activate both CB1 and CB2 receptors, when you get CB2 activated from using cannabis, it's actually coming from THC. The best type of product is what they call a full spectrum extract because the full spectrum will have the THC, and that's where the CB2 receptor activation and many of the health benefits will actually come from. Dr Lee's product is a selective CB2 agonist or an activator. And that means it activates CB2 receptors without activating the CB1. Hence, you get all the health or physiological benefits of activating CB2 receptors but none of the intoxications that comes with CB1 activation. [47:44] Dog Anxiety: How to Safely Use Cannabis to Help Your Dog Every vertebrate mammal has an endocannabinoid system. Dr Lee has a product called Dog Ease CB2, their top seller on Amazon. Dog Ease CB2 have healthcare approval. People use Dog Ease CB2 for stress-related behavior in dogs, whether it's separation anxiety, thunders, or anything that makes a dog nervous. Cats also metabolize terpenes at a much slower rate than humans and dogs. The dose given to cats is a fraction of what the dog label says. AND MUCH MORE! Resources from this episode: Get Cannanda products here (coupon code applied) https://www.cannanda.com/KETOKAMP Follow Dr Lee Know: LinkedIn: https://www.linkedin.com/in/leeknow/ Twitter: https://twitter.com/leeknow3d?lang=en Facebook: https://www.facebook.com/CannandaCrew Instagram: https://www.instagram.com/CannandaCrew/ Dr. Lee Know on Amazon: https://www.amazon.com/Mitochondria-Future-Medicine-Understanding-Disease/dp/1603587675/benazadi-20 https://www.amazon.ca/CBD-Hemp-Oil-For-Dogs/dp/B08H5ND2J2/benazadi-20 The Documentary mentioned during the episode: https://vimeo.com/ondemand/207515 Join the Keto Kamp Academy: https://ketokampacademy.com/7-day-trial-a Watch Keto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E S P ON S O R S ⭐ Bioptimizers Magnesium Breakthrough. Get the best night of sleep ever. NO OTHER supplement on the market offers 7 types of magnesium in 1 bottle. Visit bioptimizers.com/ketokamp and use promo code ketokamp10 for 10% off your first order. ⭐ Upgraded Formulas | http://www.upgradedformulas.com Purchase Upgraded Formulas, Charge Electrolytes, and other products. GET 15% OFF with Coupon Code: KETOSIS Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. Some links are affiliate links // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸ tiktok | @thebenazadi https://www.tiktok.com/@thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. 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