Podcasts about endocannabinoids

For nearly a century, scientists believed we had discovered ALL of the essential fatty acids the human body needs. But what if they were wrong? Stephanie Venn-Watson, a veterinary epidemiologist and longevity researcher, joins Dave to reveal a groundbreaking discovery—a newly identified essential fatty acid, C15, that may hold the key to healthier aging and even longer lifespans. Originally uncovered in an unlikely place—U.S. Navy dolphins that were outliving their wild counterparts by decades—this forgotten fat is now shaking up the scientific community. So why hasn't anyone told you about it?? Decades of misguided dietary advice stripped this crucial nutrient from our food system, leaving an entire generation unknowingly deficient. Even worse, pregnant women have been some of the MOST hurt from this cruel change to our modern diet. Now, cutting-edge research is proving that C15 plays a critical role in cellular stability, mitochondrial function, and total mental health. What You'll Learn in This Episode: • The first new essential fatty acid discovered in nearly 100 years—and why it matters • How dolphins led to one of the BIGGEST breakthroughs in human nutrition • Why the removal of C15 from our diets is accelerating aging • The surprising connection between C15 and mental health • How this “missing” fat could outperform some of the biggest longevity drugs today! • What foods naturally contain C15—and should you supplement it? *** Get 15$ off Fatty15 at www.fatty15.com with code: DAVE *** SPONSORS Puori | Visit https://puori.com/dave and use code DAVE for 20% off.Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Fatty15 Instagram – https://www.instagram.com/fatty15/ • Fatty15 Website: www.fatty15.com • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 – Intro 00:34 – Meet Dr. Stephanie Venn-Watson 00:46 – Discovering C15 in Navy Dolphins 01:58 – Challenges and Skepticism 04:21 – Scientific Validation and Research 06:59 – C15's Impact on Human Health 27:43 – Big Data, AI, and Longevity Research 36:08 – C15 as a Longevity Nutrient 42:14 – The Navy's Role in Fatty 15 43:03 – Epigenetic Aging and Lifespan 44:51 – Nutritional Guidelines and C15 Deficiency 50:41 – Mental Health and Endocannabinoids 51:33 – Dairy, Fats, and Nutrition History 56:38 – Fatty 15 in Skincare and Supplements 01:03:58 – Regulatory Changes in Nutrition 01:11:26 – Gender Differences in Fatty Acids See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A quick update that early registration is now open for Thom's upcoming annual retreat in Sedona, Arizona, this Memorial Day weekend from May 22nd to 26.This is Thom's first retreat in the United States since the epic Maha Kumbha Mela held earlier this year in Prayagraj, India, so Thom has many fascinating new stories to share. The Sedona Rounding Retreat is also your opportunity to gift yourself profound rest and industrial-strength meditation through the daily rounding program. This is your chance to transcend uncertainty in the ever-changing world and celebrate spring surrounded by nature, supported by community, and immersed in wisdom with Thom.  Early registration discounts expire on March 17th, and you can find out more at thomknoles.com/sedona.Jai Guru Deva.Cannabis is widely used for relaxation and is increasingly prescribed for therapeutic purposes. But what effect does it have on our internal “balance”?In this episode, Thom addresses a listener's question about the relationship between cannabis use and the gunas—the balancing agents of Nature, as described in the Vedic worldview.Thom explains why cannabis has an impact on the body, how it interacts with our natural systems, and why our body's own “endogenous cannabinoids” provide a more sustainable and beneficial effect on our physiology.Episode Highlights[00:45] Q - How does cannabis influence the three gunas?[01:20] A - Gunas - Balance Agents of Nature[04:27] Rajas and Tamas - Change and Inertia[07:52] Go Beyond the Three Gunas[11:32] Too Many Spinning Plates[13:47] Endogenous and Exogenous Cannabinoids[17:06] Endocannabinoids from Vedic Meditation[20:11] Like Riding a Bike[22:23] A Balanced State of ConsciousnessUseful Linksinfo@thomknoles.com https://thomknoles.com/https://www.instagram.com/thethomknoleshttps://www.facebook.com/thethomknoleshttps://www.youtube.com/c/thomknoleshttps://thomknoles.com/ask-thom-anything/

In this Huberman Lab Essentials episode, I explain the biological mechanism behind motivation and drive, as well as discuss practical tools for overcoming procrastination.  I discuss the key role dopamine plays in driving cravings and motivating action. I explain how dopamine regulates the balance between pleasure and pain, and what happens when this system becomes dysregulated, leading to addiction. I discuss the role of molecules like serotonin, which help enhance the enjoyment of the present, and explain how to balance the drive for more while staying focused in the present. I also discuss the causes of procrastination and describe strategies to boost dopamine levels through behavioral approaches or supplements.  Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, and our full-length episodes will still be released every Monday. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Mateina: https://drinkmateina.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Motivation 00:01:57 Dopamine & Brain  00:04:08 Anticipation, Craving & Dopamine 00:05:37 Sponsor: AG1 00:06:46 Food, Drugs & Dopamine Release 00:10:18 Addiction, Pleasure & Pain Balance 00:14:12 Sponsors: Eight Sleep & Mateina 00:17:14 Dopamine, Pain, Yearning 00:19:08 “Here and Now” Molecules, Serotonin, Endocannabinoids, Tool: Mindfulness 00:22:42 Procrastination; Tool: Extend Dopamine, Offset Pain 00:26:15 Sponsor: LMNT 00:27:31 Dopamine & Motivation; Increasing Dopamine, Phenethylamine (PEA) 00:30:58 Dopamine Schedule, Subjectivity 00:33:59 Gambling, Intermittent Reinforcement, Tool: Blunting Rewards 00:38:51 Recap & Key Takeaway Disclaimer & Disclosures

Happy New Year! For many of us, a new year brings a renewed sense of motivation when it comes to health. Earlier this year, Russ sat down to speak with Jonathan Long, a Stanford biochemist who studies the chemicals produced during exercise. The conversation was one of our most popular during 2024 and today we're re-sharing it. As many of us look to create healthy habits in 2025, we hope you'll tune in to hear the exciting research Professor Long is doing to better understand the deep chemical connections between diet, exercise, and human health. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Jonathan Z. LongJohnathan's Lab: LongLab@StanfordConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Johnathan Long, a professor of pathology at Stanford University.(00:01:55) Effective Weight Loss DrugsThe history and development of GLP-1 receptor agonists.(00:03:27) Understanding Metabolism and ExerciseThe role of metabolic chemicals released during physical activity.(00:05:02) Animal Models in Exercise Studies The use of animal models in exercise studies and the discovery of Lac-Phe.(00:06:40) Psychological Preparation for Exercise The psychology of exercise preparation and the involvement of endocannabinoids.(00:08:53) Lac-Phe's Role and Mechanism Lac-Phe's role in suppressing appetite and its production in the gut.(00:11:46) Differences in Exercise Response Exercise response between trained athletes and untrained individuals.(00:12:50) Diabetes and Metabolic Diseases The relationship between diabetes, exercise, and metabolic diseases.(00:14:54) Lac-Phe as a Potential Therapeutic Lac-Phe's potential and parallels to the early stages of GLP-1 drug development.(00:16:13) Importance of How Weight is Lost The importance of losing fat while preserving lean muscle mass.(00:19:04) Exercise as Medicine The need to define physical activity at the same resolution as modern medicines.(00:22:03) Metformin and Exercise Pathways The unexpected connection between metformin and the Lac-Phe pathway.(00:23:53) Prospects of an Exercise Pill The future of an exercise pill, and challenges associated with its development.(00:26:57) Conclusion  Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Given the widespread legalization of cannabis for medical and recreational uses, you'd think we'd have a better understanding of how it works. But ask a neuroscientist exactly how cannabinoid compounds like THC and CBD alter our perceptions or lead to potential medical benefits, and you'll soon learn just how little we know.We know that these molecules hijack an ancient signaling system in the brain called the "endocannabinoid" system (translation: the "cannabinoids within"). These somewhat exotic signaling molecules (made of fatty lipids and traveling "backwards" compared to other transmitters) have been deeply mysterious until recently, when new tools made it possible to visualize their activity directly in the brain.So what is the "day job" of the endocannabinoid system — and how does it connect to the dramatic highs that come with taking THC or the medical benefits of CBD? To unpack all this, we're talking this week with neuroscientist Ivan Soltesz, the James Doty Professor of Neurosurgery and Neuroscience at Stanford, and a leading expert on the endocannabinoid system.Learn MoreThe Soltesz Lab"Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy" (Soltesz et al, Nature Reviews Neuroscience, 2015) "Keep off the grass? Cannabis, cognition and addiction" (Parsons et al, Nature Reviews Neuroscience, 2016)"Marijuana-like brain substance calms seizures but increases aftereffects, study finds" (Goldman, Stanford Medicine News, 2021)"Retrograde endocannabinoid signaling at inhibitory synapses in vivo" (Dudok et al, Science, 2024)Vote for us!We are a finalist for a prestigious Signal Award for Best Science Podcast of 2024! Share your love for the show by voting for us in the Listener's Choice category by October 17. Thanks in advance!Get in touch:We're doing some listener research and we want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute. Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Send us a textAbout the guest: June Round, PhD is a microbiologist whose lab at the University of Utah studies microbiome-host interactions, gut microbiota, immunity, metabolism, obesity, and other disorders.Episode summary: Nick and Dr. Round discuss: how the immune system and gut microbiome interact; dietary fiber & short-chain fatty acid production by gut microbes; nutrient absorption; obesity & metabolic syndrome; type I diabetes; cleanliness, development & the “hygiene hypothesis”; and more.Related episodes:M&M #133: Infant Microbiome & Breast Milk, Oral Microbiome & Cavities, Gut Health, Fiber, Probiotics, Diet, Sex Hormones, Soy Foods & Estrogens | Carolina TropiniM&M #103: Connections Between Microbiome, Exercise, Diet, Metabolism, Circadian Rhythms, Endocannabinoids & Health | Christoph Thaiss*This content is never meant to serve as medical advice.Support the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils, artificial ingredients, etc. Use code MIND for 20% off. SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. Learn all the ways you can support my efforts

Feeling constantly stressed or overwhelmed? CBD might be the answer, but not in the way that you think! In this episode of the Longevity podcast, I chat with Adam Wenguer, founder of Element Health, to discuss the benefits of full-spectrum CBD products.    Our conversation dives deep into how CBD interacts with our body's endocannabinoid system, potentially helping to restore homeostasis. We discuss how full-spectrum CBD helps manage stress, improve sleep, and promote overall well-being without the "high" associated with THC.   Adam Wenguer is the founder and CEO of Element Health, a company dedicated to producing high-quality, full-spectrum CBD products. With a background in performance coaching and nutrition, Adam's journey into the CBD industry was inspired by his personal experiences with stress management and overcoming addiction. Adam is committed to educating consumers about the benefits of whole-plant extracts over isolated CBD compounds. Through Element Health, he aims to help people find balance and improve their overall well-being using small-batch, premium CBD products.   Try Element Health CBD products today and Use code Longevity when shopping at https://elementhealthsupply.com/  Thank you to our sponsors for making this episode possible: Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition  Lumiram: Get your Chromalux® bulbs at https://healthlighting.com and use promo code longevity to save 10%.      Find more from Element Health:  Website: https://elementhealthsupply.com/  Instagram: @elementhealth    Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat's Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance  What We Discuss: (00:03) CBD and Endocannabinoids for Health (13:01) Benefits and Science of Endocannabinoids (21:57) Understanding CBD for Stress Relief (32:33) Balancing Full Spectrum Cannabis Products (42:36) Cannabinoid Products and Genetic Modification (56:57) Optimizing Health With CBD and Endocannabinoids  

In this episode of Hart2Heart, Dr. Mike Hart dives into the world of endocannabinoids with neuroscientist Dr. Matthew Hill. Known for his groundbreaking research in understanding how endocannabinoids influence stress and anxiety, Dr. Hill offers insights into the biological mechanisms behind these naturally occurring compounds and their potential therapeutic benefits. Dr. Hart and Dr. Hill cover everything from the endocannabinoid system's role in stress regulation, the intriguing interplay between CBD and caffeine, to the impacts of cannabis legalization on scientific research. Guest Bio and Links: Dr. Matthew Hill, Ph.D., a professor of cell biology and anatomy at the Hotchkiss Brain Institute at the University of Calgary and an expert on the biology of cannabis.  Resources:  Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart    (0:15) Dr. hart introduces guest, Dr. Matthew Hill to the listeners  (1:00) Brief background of Dr. Hill's work   (2:00) Explanation of the endocannabinoid system (6:00) CBD and caffeine interaction explained (8:30) Do CBD and caffeine cancel each other out (11:00) Importance of studying the effects of cannabis beyond THC and CBD (15:00) CBD dosage - myths and realities (21:30) The bioavailability of CBD and the importance of fatty acids (26:00) CBD and THC interaction (32:00) CBG's emerging research and potential benefits (36:30) What are beta caryophyllenes  (38:30) THCV a promising cannabinoid for diabetes? (42:00) Cannabis tracks and lifestyle choices  (46:00) Dr. Hill's recommendations for reducing cannabis dependency (48:00) The challenges of scaling back cannabis use (53:15) Vaping vs. smoking  --- Dr. Mike Hart is a Cannabis Physician and Lifestyle Strategist. In April 2014, Dr. Hart became the first physician in London, Ontario to open a cannabis clinic. While Dr. Hart continues to treat patients at his clinic, his primary focus has shifted to correcting the medical cannabis educational gap that exists in the medical community.  Connect on social with Dr. Mike Hart: Social Links: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In this podcast, Contributing Editor Berkeley Limketkai, MD, PhD, interviews Dr. Lindsey Russell on the article “Nutrition, endocannabinoids, and the use of cannabis: An overview for the nutrition clinician” published in the August 2024 issue of NCP. Business Corporate by Alex Menco | alexmenco.net Music promoted by www.free-stock-music.com Creative Commons Attribution 3.0 Unported License creativecommons.org/licenses/by/3.0/deed.en_US August 2024

Jonathan Long is a biochemist who studies the chemicals produced during exercise. In Long's world, “you always start with molecules,” which offer “clean handles” to understanding complex processes. His lab has identified a chemical produced in the digestive tract during exercise that can make a person stop eating. Long now studies this “gut-brain axis” for ways to treat obesity, diabetes, and, perhaps, even age-related conditions like dementia, as he tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Episode Reference Links:Stanford Profile: Jonathan Z. LongJonathan's Lab: LongLab@StanfordStudy on Endocannabinoids and Exercise Motivation: The Endocannabinoid System and Physical ExerciseConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionHost Russ Altman introduces guest Jonathan Long, a professor of pathology at Stanford University(00:02:30) Effective Weight Loss DrugsThe increase of effective weight loss drugs, and the history and development of these GLP-1 receptor agonists.(00:04:03) Understanding Metabolism and ExerciseOutline of metabolic chemicals released during physical activity and their potential to combat obesity and diabetes.(00:05:38) Animal Models in Exercise StudiesThe use of animal models in exercise studies and the discovery of Lac-Phe.(00:07:15) Psychological Preparation for ExerciseThe psychological aspects of exercise and the involvement of endocannabinoids in exercise motivation.(00:09:28) Lac-Phe's Role and MechanismThe role of Lac-Phe and its production in the gut.(00:12:21) Differences in Exercise ResponseDifferences in exercise response between trained athletes and untrained individuals.(00:13:25) Diabetes and Metabolic DiseasesThe relationship between diabetes, exercise, and metabolic diseases.(00:15:29) Lac-Phe as a Potential TherapeuticThe potential of Lac-Phe as a weight loss drug, and parallels to GLP-1 drug development.(00:16:48) Importance of How Weight is LostWhether the method of weight-loss matters, and the importance of preserving lean muscle mass.(00:19:40) Exercise as MedicineThe concept of exercise as medicine, and defining physical activity at the same resolution as modern medicines.(00:22:39) Metformin and Exercise PathwaysThe unexpected connection between metformin and the Lac-Phe pathway.(00:24:08) Prospects of an Exercise PillThe future of an exercise pill, and the scientific challenges associated with its development.(00:27:33) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

In this compelling episode, I am honored to welcome Adam Wenguer, a passionate advocate for natural health solutions and a visionary in the world of cannabis-derived products. As the CEO at Element Health, Adam brings his extensive knowledge and personal experiences to light, advocating for the powerful benefits of CBD and hemp. His dedication is not just to advance personal wellness but also to redefine how we engage with nature and tackle the challenges of modern living.Throughout our conversation, Adam explores the intricate balance of the endocannabinoid system and its profound impact on everything from anxiety to physical recovery. He discusses how his personal journey and professional endeavors intersect, leading to groundbreaking insights into how CBD can enhance daily life, promote better sleep, and support mental clarity. His stories from the trenches of entrepreneurship and personal health advocacy illuminate the vast potential of integrating CBD into a holistic wellness regime.This episode is essential listening for anyone interested in natural remedies, personal resilience, and environmental stewardship. Adam's narrative is a powerful reminder of the importance of reconnecting with nature, challenging conventional comfort, and the transformative potential of embracing plant-based health aids. Tune in to discover how Adam's experiences and innovations in CBD can inspire a more balanced, health-focused approach to your daily lifeKey Points From This Episode:All things CBD. [00:04:13]CBD and Cannabis Legalization. [00:08:34]The power of CBD. [00:14:37]The endocannabinol system. [00:18:29]Endocannabinoid Deficiency Study. [00:20:24]Endocannabinoids for the runner's high. [00:23:27]Technology and physiology gap. [00:29:39]The diurnal effect of the endocannabinoid system. [00:32:43]CBD for anxiety relief. [00:35:24]CBD vs. THC Sleep Effects. [00:41:17]Overcoming marijuana dependency. [00:44:43]Challenging convenience in modern life. [00:48:29]Getting back to nature. [00:50:26]Embracing discomfort for growth. [00:56:14]CBD for public speaking anxiety. [00:59:29]Getting uncomfortable for growth. [01:03:08]Young minds in biohacking industry. [01:06:41]Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today's Episode:Click HERE to save on BiOptimizers MagnesiumPeopleAdam WenguerInstagramElement HealthBen GreenfieldOfficial WebsiteInstagramTwitterSupport the show

Caterina Fede from the University of Padova joins us for the first podcast of 2024! We'll unpack fascia and hormones and endocannabinoids, the 2024 Fascia Winter School, learn Caterina's Origin Story and more! David will give some listeners stats and share a very special personal moment from 2023. The Desiderata Fascia What it is and Why it Matters --- Send in a voice message: https://podcasters.spotify.com/pod/show/david-lesondak/message

Watch Here : https://www.youtube.com/watch?v=4yEjY1IUsy8 Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve

Dr. Raphael Mechoulam was an organic chemist at the Hebrew University of Jerusalem, and the father of cannabis research. His team was the first to elucidate the structure of cannabidiol, or CBD. Dr. Mechoulam passed away in March 2023. This episode is a remastering of a conversation between Dr. Mechoulam and Dr. Meir Bialer, held in 2018 at the 13th European Congress on Epileptology. They spoke about CBD, THC, the endocannabinoid system, and the effects of cannabinoids in epilepsy and other conditions. Support the showSharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Twitter, and Instagram.

In this episode, Sophie uncovers why running makes us feel good. This is a rapid fire episode, with more depth on certain aspects coming in future ep's. She discusses the previous theory of endorphins causing this 'euphoric' feeling and a more recent idea around a naturally occurring substance, called Endocannabinoid (ECB) which could have a big role to play. As well as discussing the science and research, she also speaks on a few anecdotal reasons why she believes running is so powerful. We'd love to hear your thoughts. Why does running make YOU feel good? Scott Goddards' ep on Flow State - https://podcasters.spotify.com/pod/show/strongerstride/episodes/80--Flow-State--Goal-Setting-for-runners-w-Scott-Goddard-PHD-e1v1lkh Articles: https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1229&context=sjlcas 2019 Endorphins, Endocannabinoids and Runners' High Endorphins, Endocannabinoids and Runners' High Elisheva Winiarz https://www.researchgate.net/profile/Gregory-Gerdeman/publication/221971138_Wired_to_run_Exercise-induced_endocannabinoid_signaling_in_humans_and_cursorial_mammals_with_implications_for_the_'runner's_high https://academic.oup.com/cercor/article/18/11/2523/291108?login=false Our links: ⁠⁠Tailwind Nutrition⁠⁠ use code TAILWINDSTRONG for 15% off ⁠Vivobarefoot⁠ use code STRONGERSTRIDE for 15% off

In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom. Mind Pump Fit Tip: Isometric contraction training yields INCREDIBLE strength! (3:01) Mind Pump recommends ‘The Deepest Breath' on Netflix. (30:04) Endocannabinoids neuromodulating effects. (41:49) Speculating on how the Maui wildfires started and how the administration will help. (46:51) Congress is the most corrosive part of our government. (55:43) Busting the myth surrounding GLP-1 receptors. (59:43) Shout out to Mike Yoder, Esq. (1:01:20) Weaning off caffeine and boosting your endurance stamina with the Red Juice from Organifi. (1:01:54) #ListenerLive question #1 - How would you recommend dieting and training while recovering from an injury? (1:05:01) #ListenerLive question #2 - What should I be doing, and how should I start? I'm 18 and I want to build as much muscle as possible so that I can look and feel amazing. (1:24:37) #ListenerLive question #3 - Do you have any advice on how to transform my dependency on video workouts? (1:33:36) #ListenerLive question #4 - What is appropriate to do on the trigger days? (1:44:08) Related Links/Products Mentioned Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com Visit NED for an exclusive offer for Mind Pump listeners! Visit Organifi for the exclusive offer for Mind Pump listeners! **Promo code MINDPUMP at checkout** Special Launch Promotion: MAPS Old Time Strength for $80 Off (Retail $177, Includes 2 eBooks: Forgotten Muscle & Strength Building Secrets, PLUS Jay Campbell's Living a Fully Optimized Life.  30 Day money back guarantee // Ends Sunday, August 27th. **Code OLD80 at checkout** August Promotion: MAPS Anabolic Advanced 50% off! **Code AUGUST50 at checkout** Mind Pump #2145: Forgotten Muscle & Strength Building Secrets Dynamic Tension: A Bodyweight Training Method by Charles Atlas Don't be Half a Man – Charles Atlas ad MindPump Co-Host Justin Andrews Talks High School Football Training w/ Joe D! Watch The Deepest Breath | Netflix Official Site Exercise-Induced Endocannabinoids Boost Brain Plasticity Maui wildfires spark conspiracy theories about space lasers, Oprah land grabs and suspicious trees Green laser beams spotted off Hawaii from Chinese satellite: experts NFL or NBA reaction video Visit Eight Sleep for an exclusive offer for Mind Pump Listeners! **Save $150 on the Pod Cover.** MAPS 15 Minutes Meditations: A New Translation Mind Pump #1447: How To Start Your Fitness Journey Mind Pump #2105: How To Become A Muscle Mommy Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Ben Pakulski (@bpakfitness) Instagram Joe DeFranco (@defrancosgym) Instagram Mike Yoder (@yoder_esq) Instagram

Nick talks to Dr. Matthew Hill, a neuroscientist at the University of Calgary whose lab studies how the endocannabinoid system and cannabis (marijuana) influence the brain & behavior. They discuss: endocannabinoid biology; endocannabinoid regulation of stress & anxiety; endocannabinoids & exercise; how marijuana & THC influence brain development; and more.See previous episode with Dr. Matthew Hill: https://mindandmatter.substack.com/p/matthew-hill-endocannabinoid-system-8ff#detailsSupport the showSign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Become a Premium Subscriber to access full content library, including full premium episodes:[https://mindandmatter.substack.com/subscribe?utm_source=menu&simple=true&next=https%3A%2F%2Fmindandmatter.substack.com%2F]Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off:[https://www.lumen.me/shop?fid=8731&utm_source=influencer&utm_medium=influencer&discount=MIND]

Melissa Gibson is a World Champion snowboarder and founder of hemp&humanity, a company dedicated to unleashing the boundless, endless potential of the hemp plant. In this conversation with Melissa we discuss:How she used hemp to heal from multiple health conditionsHow the endocannabinoid system works to help the body achieve homeostasisThe 2023 Farm Bill and how it affects hempWhy hemp seeds should be a part of your dietThe Entourage EffectYou can learn more about Melissa at hempandhumanity.com or follow her work on Instagram.Terrain Theory episodes are not to be taken as medical advice. You are your own primary healthcare provider.If you have a Terrain Transformation story you would like to share, email us at ben@terraintheory.net.Learn more at www.terraintheory.netMusic by Chris Merenda

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.18.537293v1?rss=1 Authors: Kroll, S. L., Hulka, L. M., Kexel, A.-K., Vonmoos, M., Preller, K. H., Treyer, V., Ametamey, S., Baumgartner, M. R., Boost, C., Pahlisch, F., Rohleder, C., Leweke, F. M., Quednow, B. B. Abstract: Animal models indicate that the endocannabinoid system (ECS) plays a modulatory role in stress and reward processing, both crucially impaired in addictive disorders. Preclinical findings showed endocannabinoid-modulated synaptic plasticity in reward brain networks linked to the metabotropic-glutamate-5 receptor (mGluR5), contributing to drug-reinforcing effects and drug-seeking behavior. Although animal models postulate a link between ECS and cocaine addiction, human translational studies are lacking. Here, we tested previous preclinical findings by investigating plasma endocannabinoids (eCBs) anandamide (AEA), 2-arachidonoylglycerol (2-AG), and the related N-acylethanolamines (NAEs) palmitoylethanolamide (PEA) and oleoylethanolamide (OEA), including their interaction with cerebral mGluR5, in chronic cocaine users (CU). We compared basal plasma concentrations between chronic CU (N=103; 69 recreational CU and 34 dependent CU) and stimulant-naive healthy controls (N=92). Follow-up basal eCB/NAE plasma levels after 12 months were used for reliability and stability check (CU: N=33; controls: N=43). In an additional analysis using 11C-ABP688 positron emission tomography (PET) in a male subsample (CU: N=18; controls: N=16), we investigated the relationships between eCBs/NAEs and mGluR5 density in the brain. We found higher 2-AG plasma levels in dependent CU compared to controls and recreational CU. 2-AG levels were stable over time across all groups. In the PET-subsample, a positive association between 2-AG and mGluR5 brain density only in CU was found. Our results corroborate animal findings suggesting an alteration of the ECS in cocaine dependence and an association between peripheral 2-AG levels and cerebral mGluR5 in humans. Therefore, the ECS might be a promising pharmaco-therapeutic target for novel treatments of cocaine dependence. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

In this episode, Dr Nancy Speaks with Dr Erin Pollinger.  Dr. Erin Pollinger is a Chiropractor of almost 20 years, a life coach supporting people around physical and financial freedom.  She shares how women are bombarded with stress (physical, emotional, chemical and financial) and are in a constant state of tension.  When women are stuck in this stress response they are not able to make healthy choices and changes. This forces them to stay stuck in unhealthy relationships, eating patterns and financial situations.  When we become unstuck we can reconnect with our radiance, magnetism and power. If you are feeling stressed, have pain or feel stuck in some way in your life….this is a must! Follow Dr Nancy on Instagram: https://www.instagram.com/drnancycrowell   Join Dr Nancy's Fullscript Dispensary for 15% off high-quality professional supplements from some of your favorite brands on every order.  https://us.fullscript.com/welcome/drnancycrowell/signup

This week's episode does feature some bonus content which you can access HERE and at the link and become a member of the Coffee Club to unlockBefore we go on: a little disclaimer -The information provided in this episode is intended to be, educational in nature and informational. In this episode we are not diagnosing, treating, or offering a cure to any medical condition. Please consult your doctor before starting any new self-help program. Statements made about the medical effectiveness of cannabis, pot, weed, ganja, or any other off shoot of cannabis plant has not been evaluated by the Federal Drug Administration. Today, our guest is Rebecca Smolenski. She's a 2 time DARE essay award winner, and someone voted least likely to leave their corporate career to join the cannibis industry. Rebecca is the proprietor of “Highly Well”, a Cannabis coaching practice here in Cleveland, Ohio. She's going to uncomplicate the cannabis situation here in Ohio and beyond.SPECIAL OFFER FOR LISTENERS OF THE PODCAST:$50 off CBD guides at Highly Well just mention the Podcast when you book, runs till 1.31.2023 If you book at all, mention the podcast. Services are available nationwide so check in, and she can hook it up. Highly Well - http://highlywellcle.com Endocannabinoids article from Harvard National Museum of Civil War MedicineAmerican's concerns of Marijuana in the 1930s: https://www.jstor.org/stable/41108749Ohio DARE program: https://dare-oh.org/Survive Everyday InstagramSurvive Everyday FacebookSurvive Everyday GroupRyan-St Marie Insurance AgencySupport the show Support the show

The incredibly balancing endocannabinoid system's benefits are being overshadowed by the stigma of marijuana and getting high.  Unfortunately, most educators and medical providers are not fully educated or have written off medical marijuana as an ineffective medicine due to it's stigma.  Sadly, what's being overlooked is that research has found life's stress depletes the endocannabinoids that provide calm and balancing within your body.  There are many plants, not just just the cannabis plant utilizing this same pathway to help restore balance.  Many are finding that using cannabis in combination with other plant medicine or on it's own is providing the sedative effects they desire.  As a nurse Ashley Wynn-Grimes found that many patients were benefitting from cannabis but were feeling stigmatized for their use of medical marijuana.  So Ashley founded Cannabis  Nursing Solutions, authored two books “Stigmatized”, and  the children's book “Asa's Medicine” to empower patients and nursing professionals to make informed wellness choices when it comes to cannabis.  She's since went on to create educational medical programs for nurses to better understand and educate patients on their choices and options when it comes to using cannabis based medicine.  In this episode of The Health Fix Podcast, Dr. Jannine Krause interviews Ashley Wynn-Grimes on how your endocannabinoid system works to help you maintain balance in the body. What You'll Learn in This Episode: How linolool is a relaxing terpene in cannabis & lavender How the vagus nerve works with your endo-cannabinoid system How cannabinoids work synergistically to help the body breathe and reset. Why stress depletes your cannabinoid levels & your cannabinoid system   Resources From the Show: Ashley Wynn-Grimes - www.cannabisnursingsolutions.com Ashley Wynn-Grimes - Instagram - @cannabisnursingsolutions   Enjoy The Show? Never Miss An Episode Subscribe, Rate and Review the show in iTunes Subscribe via Stitcher or RSS feed Send us feedback via Email Leave a comment below

Nick talks to biologist Dr. Christoph Thaiss, a professor at the University of Pennsylvania. His lab studies how the body detects & responds to environmental stimuli, with a focus on interactions between the gut microbiome, immune & nervous systems. They discuss: sensory systems of the body & basic principles of how they work; gut microbiome & the consequences of depleting it with antibiotics; endocannabinoids & exercise; how microbiome composition influences the brain & motivation to engage in exercise; prebiotics & probiotics; circadian rhythms & eating patterns.SUPPORT M&M:Sign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Support the show

Debbie Wilson joins the Lonestar Collective Podcast this week with host Gramps. Debbie is the CEO and founder of Neurology and Endocannabinoids on Facebook and the CEO of https://www.noahsarkconsulting.org/ Find us on social media Facebook: https://www.facebook.com/txcancollective Twitter: https://twitter.com/txcannaco Instagram: https://www.instagram.com/txcannabiscollective/ Youtube: https://www.youtube.com/c/TexasCannabisCollective Web: https://txcannaco.com

Debbie Wilson joins the Lonestar Collective Podcast this week with host Gramps. Debbie is the CEO and founder of Neurology and Endocannabinoids on Facebook and the CEO of https://www.noahsarkconsulting.org/ Find us on social media Facebook: https://www.facebook.com/txcancollective Twitter: https://twitter.com/txcannaco Instagram: https://www.instagram.com/txcannabiscollective/ Youtube: https://www.youtube.com/c/TexasCannabisCollective Web: https://txcannaco.com

Pt. 1 of 2. Let's talk about Cannabis, Endocannabinoids, Stigma, and Wellness. --- Send in a voice message: https://anchor.fm/thepaintedfool/message

Today, Paul interviews Tucker Goodrich, Wall Street technology extraordinaire and independent researcher, and Jeff Knobbs, co-founder and CEO of Zero Acre Farms. They take a deep dive into the epidemic of seed oil consumption. They examine conflicting arguments, and then explain why seed oils are likely making humans fat, diabetic, and causing atherosclerosis. A note from Paul: Throughout my training and practice as a physician I have come to one very disappointing conclusion:  Western medicine isn't helping people lead better lives. Now that I've realized this, I've become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you'll join me on this journey. Time Stamps: 00:08:14 Podcast begins 00:13:55 What are seed oils and why are they bad for us? 00:23:30 Ancestral consistency of seed oils and linoleic acid 00:42:40 How are seed oils processed? 00:51:40 Should we worry about trans fats? 00:56:40 Let's talk about HNE and PUFAs 01:13:10 Endocannabinoids 01:30:40 Are seed oils inflammatory? 00:01:43 Diverticulosis 01:47:20 Seed oils & blindness 01:48:45 Closing remarks about linoleic acid Connect with Jeff: zeroacre.com jeffnobbs.com Connect with Tucker: yelling-stop.blogspot.com Sponsors: Heart & Soil: www.heartandsoil.co Carnivore MD Merch: www.kaleisbullshit.shop Make a donation to the Animal Based Nutritional Research Foundation: abnrf.org  White Oak Pastures: www.whiteoakpastures.com, use code CarnivoreMD for 10% off your first order or Carnivore5 for 5% off subsequent orders Our Sponsor LetsGetChecked: 20% off your order at www.TRYLGC.com/paulsaladino for 25% off  Marek Health: marekhealth.com/fundamentalhealth, use code PAUL for 10% off your first lab order Colima Salt: drpaulsalt.com, for a free bag of Colima Sea Salt

Grandpa Bill Today asks do you experience any of the following conditions or maladies? Fatigue Depression Anxiety Economic and Financial Stress Here's How CTFO provides major disruptor CBDa Derived Products with our Exclusive products & advancing CTFO Technology https://bhsales.myctfo.com/index.html WHY YOU NEED TO BALANCE YOUR ENDOCANNABINOID SYSTEM When your body isn't in balance, it can wreak havoc on your life, emotions, and overall well-being. At Well Theory, we provide resources, products, education and more to help you achieve balance in your life through small lifestyle changes. If you don't feel 100% your best, physiologic imbalance is likely at the core of your struggles. An unbalanced immune system, overeager inflammatory response, chaotic hormonal system and more can impact your overall wellness and outlook on life. If you've struggled with recurring pain, inflammation, or anxiety, you've likely searched for a safe solution to your condition. And your search likely turned up one promising answer to your problems: Cannabidiol (CBD.) Cannabidiol, Endocannabinoids, Anxiety, Generalized anxiety disorder, Post-traumatic stress disorder https://holisticbill.wixsite.com/mysite/blog https://bhsales.vpweb.com/default.html? --- Send in a voice message: https://anchor.fm/bhsales/message

The Endocannabinoid System If you'd like to keep up with everything else we do please visit https://strangeapothecary.co.uk Join our community - https://www.facebook.com/groups/strangeapothecary What is The Endocannabinoid System? The Endocannabinoid System (or ECS for short) is a complex cell-signalling system in the body that is responsible for maintaining homeostasis (balance) in virtually every system in the body. The ECS was identified in 1992 by Professor Raphael Mechoulam and his researchers who were exploring exactly how the Cannabinoid, THC, works in the body. The Endocannabinoid System plays a role in your body's functions such as sleep, mood, appetite, memory, reproduction & fertility. There are three main parts to our Endocannabinoid System (ECS): Endocannabinoid molecules Cannabinoid receptors Enzymes Endocannabinoids are molecules made by your body. The 2 known Endocannabinoids are 2-AG & Anandamide. These help keep the body's internal functions running smoothly. Your body produces them as needed so it's hard to keep track if there's a deficiency. The Cannabinoid receptors around our body are called CB1 & CB2. CB1 receptors are mostly found in the central nervous system. CB2 receptors are mostly found in your peripheral nervous system, especially immune cells. Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to. There are two main enzymes: fatty acid amide hydrolase monoacylglycerol acid lipase These are responsible for creating endocannabinoids, transporting them to our receptors and breaking down endocannabinoids once they have performed their function. Research has linked the ECS to the following processes: Appetite and digestion Metabolism Chronic pain Inflammation Mood Learning and memory Motor control Sleep Cardiovascular system function Muscle formation Bone remodelling and growth Liver function Stress Reproductive system function Skin and nerve function Ways to give your Endocannabinoid System a boost. Take a Cannabinoid supplement like CBD. Try aerobic exercise. Add Cacao & Maca roots to your diet. Look for other herbs with Cannabinoid properties. Supplement omega-3. The Endocannabinoid System is still significantly underestimated and is still being researched today. We highly recommend you do some extra research because we haven't even scratched the surface in this video, This is just basic knowledge to help get you started. Thanks for joining us on today's episode, we hope you learned something new. Please like, subscribe & ding the bell so you don't miss future uploads. Sources: CBD E-Book by Hannabis - https://strangeapothecary.co.uk/product/free-cbd-ebook/ The CBD Bible by Dr Dani Gordon - https://amzn.to/3PEXZGG The Rebel's Apothecary by Jenny Sansouci - https://amzn.to/3PoCSsE

Action point: www.accessiblecountryside.org.uk A fantastic resource for those with mobility considerations in the UK. Gives a comprehensive range of maps to accessible routes around the UK countryside. Definitely pop over there and have an explore and pass it on to anyone you think might find it useful. On to the episode! Annabel Abbs is a writer of fiction and nonfiction and in this episode we discuss her book 52 Ways to Walk. We had this conversation a few weeks ago and with everything that's going on in the world right now, it's been so lovely editing it and just listening to a chat about walking! In this episode we discuss: Her journey in walking (pardon the pun!) Her no-car promise to herself How an accident that left her immobile caused her to recognise her privilege in being able to walk and inspired her to write about women walking Why she prefers walking to running The value of walking in creative thinking The part that walking plays in Annabel's creative process Endocannabinoids and walking Walking as rebellion The concept of ‘walking deep' The joy of graveyards! Lessons from her journey and her hope for the future Great episodes to accompany this one are: Anna Neubert-Wood, WanderWomen Scotland 1.2a Lucy Jones, Losing Eden 1.9a Jini Reddy, ‘Wanderland' 1.10a Dr Sheree Mack, Representation in Nature as a Path to Oneness 1.12a Lorraine Tindale, Nature-based EMDR 2.3a You can find Annabel on her website www.annabelabbs.com or on Insta, Twitter and Facebook all @annabelabbs I've added 52 Ways to Walk as well as Windswept, one of the books we discuss in the episode to my bookshop on bookshop.org so please feel free to have a look over there. I'll get a little kick back if you order through my shop, which helps me to keep the podcast going. Thank you! You can also pop to your local library if you're a library user and ask them to order it in. As always I'm www.promptedbynature.co.uk or on the socials @prompted.by.nature Remember to listen in to the writing prompt that follows this episode. Happy listening! Helen x

In this episode, I will be breaking down what cannabinoids are and discussing some basic facts you should know about cannabinoids. Grab your coffee, tea or popcorn and come along on this cannabis educational journey. Reference: https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know

If you'd like to keep up with everything else we do please visit https://hannabis.co.uk Join our community - https://www.facebook.com/groups/shroomsmoons Chapters 0:00 - Intro 0:10 - What is CBD? 0:20 - CBD & THC 0:36 - Other identifiable components 0:58 - Legal CBD 1:15 - Types of CBD 1:44 - CBD Products 2:02 - Extraction Methods 2:15 - Co2 Extraction 2:35 - How does CBD work? 2:51 - Endocannabinoid & Receptors 3:02 - How does the Endocannabinoid System work? 3:18 - Summary 3:25 - Outro CBD aka Cannabidiol is one of over 100 cannabinoids present in Cannabis. CBD & THC are the 2 most common Cannabinoids that people know about. THC being a psychoactive Cannabinoid and CBD being a non psychoactive Cannabinoid. Along with CBD & THC there are 481 other identifiable chemical components known to exist in the cannabis plant, including terpenes. Terpenes are aromatic compounds found in many plants, though many people commonly associate them with cannabis because cannabis plants contain high concentrations of them. For CBD to be legal in the UK it must be derived from hemp, contain less than 0.2% THC and any products must clearly state the amount of CBD in mg on the packaging. If a product doesn't show this, DON'T spend your money on it. There are 3 different types of CBD that you may see on the market. Isolate - This is CBD isolated from the other compounds found in the cannabis plant. Full Spectrum - This is CBD along with the other cannabinoids found in the cannabis plant. Broad Spectrum - This is CBD with the other compounds but with THC removed. You may see these types of CBD in all kinds of different products such as... Pure oil Tinctures Creams Balms Bath Bombs Soap Haircare Skincare E-liquids Tea & Coffee Chocolate Lollipops Soft drinks and many, many more. The list is endless. In order to make these products, CBD & other cannabinoids must be separated from the plant matter. This can be done in a few different ways with one of the most common being the C02 extraction method. CO2 extraction is a process that uses pressurized carbon dioxide to pull the desired phytochemicals from a plant. In the world of cannabis, the process pulls all of the essential cannabinoids, terpene oils and waxes out of the plant material. How does CBD Work? CBD works alongside our endocannabinoid system to aid better health and wellness. The endocannabinoid system is a complex cell signalling system found throughout the brains and nervous systems of all mammals. Endocannabinoids and the receptors they bind to exist in The brain The nervous system Glands Immune cells Organs Connective tissues The ECS works to balance vital functions, affecting everything from; Sleep Appetite Inflammation Pain Memory Mood Reproduction In summary Cannabinoids and The ECS are like a lock & key, made for each other. Thanks for joining us on today's episode we hope you learned something new. Please like, subscribe & ding the bell so you don't miss future uploads. Sources: https://hannabis.co.uk/product/free-cbd-ebook/ The CBD Bible by Dr Dani Gordon Aurora Europe

Are you curious about marijuana's effects on your brain? I was. To get the answers, I sat down with Neuroscientist Dr. Istvan Katona. Dr. Istvan Katona is a professor of Neuroscience at Indiana University, specializing in the research of marijuana and teaching on the Molecular, Cellular and Circuit Mechanisms of Addiction. He explains very frankly the science of Endocannabinoids, THC receptors, and the potential negative effects of smoking weed. EMAIL DR. ISTVAN KATONA ikatona@iu.edu SPONSORS SneakerCreatures: https://www.sneakercreatures.com/ USE PROMO CODE: NICKLUGO for 10% discount on all sneakers PODCAST INFO: Podcast website: https://nick-lugo.com/ Apple Podcasts: https://podcasts.apple.com/us/podcast/lugos-journey/id1527159307?uo=4 Spotify: https://open.spotify.com/show/1OrMPWEyIGIdQpBkNEZqe0 RSS: https://feeds.captivate.fm/nicklugoshow/ YouTube Full Episodes: www.youtube.com/NickLugoShow YouTube Clips: www.youtube.com/channel/UC_IEc5zSq7grb4lgGGEcqUw SUPPORT and CONNECT: – Twitter: https://twitter.com/NickLugooo – Instagram: https://www.instagram.com/nick.lugo/ – LinkedIn: https://www.linkedin.com/in/nick-lugo-2a7124208/ – Facebook: https://www.facebook.com/nicholas.lugo.311 – Email: nicholasanthonylugo@gmail.com

Hello everyone, we are back with another episode. I had the pleasure of chatting with someone in his 20s, who realized weed is no longer helping him. After making a decision to quit, he started running daily and sharing daily struggled with his close friends and family. This is more of a classic style of the episode, where I get to interview the guest from the beginning of his use all the way to the quitting and the new life, and identity.Let me know what you think about the episode, also don't forget to click like/subscribe and follow.Thank you to our anonymous guest.We have a community, join us!Chapters:00:00 Podcast intro03:41 Where did this whole thing with weed start?06:53 When is the first time you noticed that's now what you want to do?09:46 How do marijuana withdrawals make you feel?11:21 Did you have any relapses on your journey?12:26 What was one thing that changed everything for you?13:32 Telling my roommate I want to quit marijuana16:14 How did you start with the exercise?19:23 The endocannabinoid system21:16 What would you say to someone who says they cannot exercise?24:40 How is your anxiety now, after two weeks?27:09 A research on the endocannabinoid system32:56 How did the r/leaves community help you?40:08 Guest's last words43:19 Podcast outroOver and out- Anze

This episode is also available as a blog post: https://www.greennexus.us/blog/about-raphael-mechoulam Featured: Barneys Farm & Dutch Passion

It's long been accepted that the edible experience and “the munchies” go hand in hand. But one edible is aiming to change that. In this episode, Arthur Jaffe joins Jonathan to discuss a new type of gummy hitting the market that actually curbs your hunger. Arthur is the CEO of ECS Brands, a company that's in the business of providing unique whole-plant extracts to brands, manufacturers, and processors around the world. On the pod, Arthur talks about developing the Wana Optimals Fit Gummy in partnership with Wana Brands, as well as the positive results people have been seeing with the product. He also gets into some of the ingredients in the edible, notably THCV, and emphasizes the need to focus on the endocannabinoid system in the edible creation process.

Health care has been a constant presence in Matt Parks's life for much longer than most people. His mother is an ER nurse. His older brother was born with a rare condition and was often hospitalized as a child. And as a college baseball player, Matt started taking nonsteroidal anti-inflammatory drugs (NSAIDs) to cope with a shoulder injury. He became dependent on the medications and started to experience migraines. He also developed depression when his parents divorced, which he still struggles with. By 2019, having been Vice President and Sales Manager at Williams Medical Supply Inc. for over a decade, Matt was a veteran of the medical supply industry. Conversations with people in his field who had looked into cannabidiol — better known as CBD — and customers who had used it, convinced him that the majority of CBD products were ineffective. This inspired him to see if he could come up with something better. He had three main areas of improvement. He wanted to create a hemp-derived topical CBD cream that he could verify did not contain tetrahydrocannabinol (THC), the main psychoactive compound in cannabis. He also wanted to build a company that was directly accessible to customers who had questions, and a brand that didn't traffic in the usual hype. That year, he founded One Less CBD — as in “one less pill to take.” Listen to this episode of Back Talk Doc to find out what CBD is and isn't, how to choose a CBD product, and to hear about Matt's journey from patient to employee to entrepreneur.

Nick talks to Saoirse O'Sullivan, PhD, a physiologist specializing in the physiological effects of cannabinoids. Dr. O'Sullivan ran a lab at the University of Nottingham for many years before becoming a consultant and Vice President of Translational Research at Artello Biosciences. Nick and Saoirse discussed some of the physiological effects of cannabinoids in the body, including endogenous cannabinoids that our own bodies produce, and plant cannabinoids associated with the Cannabis plant (e.g. THC, CBD, THCV, and CBG). They cover a number areas of physiology and systems in the body, including inflammation, brain injury, the blood-brain barrier, gut health, and the cardiovascular system. Towards the end, Saoirse also described why she eventually made the transition from academia to the private sector, and motivated her decision to do so despite having been a successful researcher and being granted tenure as a professor.USEFUL LINKS:Download the podcast & follow Nick at his website[www.nickjikomes.com]Support the show on Patreon & get early access to episodes[https://www.patreon.com/nickjikomes]Sign up for the weekly Mind & Matter newsletter[https://mindandmatter.substack.com/]Athletic Greens, comprehensive daily nutrition (Free 1-year supply of Vitamin D w/ purchase)[https://www.athleticgreens.com/mindandmatter]Try MUD/WTR, a mushroom-based coffee alternative[https://www.mudwtr.com/mindmatter]Discount Code ($5 off) = MINDMATTEROrganize your digital highlights & notes w/ Readwise (2 months free w/ subscription)[https://readwise.io/nickjikomes/]Start your own podcast (get $20 Amazon gift card after signup)[https://www.buzzsprout.com/?referrer_id=1507198]Buy Mind & Matter T-Shirts[https://www.etsy.com/shop/OURMIND?ref=simple-shop-header-name&listing_id=1036758072§ion_id=34648633]Connect with Nick Jikomes on Twitter[https://twitter.com/trikomes]​​​Learn more about our podcast sponsor, Dosist[https://dosist.com/]ABOUT Nick Jikomes:Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, a technology startup in the legal cannabis industry. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.Support the show (https://www.patreon.com/nickjikomes)

Walking is a brilliant form of exercise but it's often overlooked in favour of running or yoga or HIIT workouts. Because we are exercise sloths and busy women, we're always looking for quick and easy ways to get moving. If you're trying to get fit and healthy, walking is one of the most accessible types of exercise you can do. Gab and Sarah look at some good quality research which shows why walking is really, really good for you. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Sarah's Burpees for Boobs Sydney Breast Cancer Foundation fundraiser Walking for hypertension Association of Step Volume and Intensity With All-Cause Mortality in Older Women Kathy Smith power walking audio workout Waking Up with Sam Harris Heavyweight podcast WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Have you ever tried Pilates? It's a popular form of exercise that was developed by Joseph Pilates in the early 20th century.  It's now a worldwide fitness trend and it's often used as a form of rehabilitation for lower back pain or injury, and recovery after childbirth.  Gab and Sarah look at what Pilates actually involves and if it lives up to the hype. Plus, another batshit crazy fitness trend, this time involving Kate Hudson and a bag full of water.  Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Cochrane Library Pilates for low back pain Jessica Valant - Gentle Pilates 15 Minute Pilates for Beginners Workout WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

How many times have you set yourself a big fitness goal? Did you achieve it? Research shows that having really specific and fixed goals can actually be a deterrent rather than a motivator.  In recent years there's been a shift away from the traditional method of goal-setting known as SMART goals (specific, measurable, achievable, realistic and timebound); towards a more flexible approach. Gab and Sarah explain the idea behind ‘open goals', and how this is proving to be a more effective way of achieving a fitness target. You'll also hear about the world record for planking, and a review of Maddie Lymburner's Low Impact Full Body HIIT workout. Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: ABC Try setting an open goal for your New Year's resolution if you want to exercise more  MadFit Low Impact FULL BODY HIIT Workout (No Equipment + No Jumping) Yoga With Adriene Wind Down Yoga (12 minute bedtime yoga) WLY Spotify playlist The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

Learn about why you eat more when you're tired; a legendary submerged Egyptian city; and a trick for keeping the peace. Lack Of Sleep Really Does Make You Eat More by Ashley Hamer Sleep Munchies: Why It's Harder To Resist Snacks When We're Tired. (2016, March 2). NPR.org. https://www.npr.org/sections/thesalt/2016/03/02/468933610/sleep-munchies-why-its-harder-to-resist-snacks-when-were-tired ‌ Circadian Surprise: How Our Body Clocks Help Shape Our Waistlines. (2015, March 10). NPR.org. https://www.npr.org/sections/thesalt/2015/03/10/389596946/circadian-surprise-how-our-body-clocks-help-shape-our-waistlines  Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite | Annals of Internal Medicine. (2021). Annals of Internal Medicine. https://www.acpjournals.org/doi/abs/10.7326/0003-4819-141-11-200412070-00008  Hanlon, E. C., Tasali, E., Leproult, R., Stuhr, K. L., Doncheck, E., de Wit, H., Hillard, C. J., & Van Cauter, E. (2016). Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. Sleep, 39(3), 653–664. https://doi.org/10.5665/sleep.5546 ‌ Insufficient Sleep Undermines Dietary Efforts to Reduce Adiposity | Annals of Internal Medicine. (2021). Annals of Internal Medicine. https://www.acpjournals.org/doi/10.7326/0003-4819-153-7-201010050-00006?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&  We just found an ancient Greek military ship in the legendary SUBMERGED Egyptian city Thônis-Heracleion by Steffie Drucker  Berman, R. (2021, July 28). Ancient Greek military ship found in legendary, submerged Egyptian city. Big Think; Big Think. https://bigthink.com/surprising-science/thonis-heracleion  ‌Sharpe, E. (2016, May 16). British Museum dips its toes into world of underwater archaeology. Theartnewspaper.com; The Art Newspaper. https://www.theartnewspaper.com/news/british-museum-dips-its-toes-into-world-of-underwater-archaeology  ‌Reuters. (2021, August 10). Egypt finds ancient military vessel, Greek graves in sunken city. Reuters; Reuters. https://www.reuters.com/world/africa/egypt-finds-ancient-military-vessel-greek-graves-sunken-city-2021-07-19/  ‌In Photos: The sunken city of Thônis-Heracleion in Alexandria reveals new archaeological treasures - Heritage. (2020). Ahram Online; Ahram Online. https://english.ahram.org.eg/NewsContentP/9/417416/Heritage/In-Photos-The-sunken-city-of-Th%C3%83%C2%B4nisHeracleion-in-A.aspx  Writing about relationship conflicts from a third-person perspective can keep the peace by Steffie Drucker Expressive writing reduces relationship conflict and aggression during pandemic. (2021, August 10). EurekAlert! https://www.eurekalert.org/news-releases/924973  Rodriguez, L. M., Stewart, S. H., & Neighbors, C. (2021). Effects of a brief web-based interpersonal conflict cognitive reappraisal expressive-writing intervention on changes in romantic conflict during COVID-19 quarantine. Couple and Family Psychology: Research and Practice. Advance online publication. https://doi.org/10.1037/cfp0000173  Follow Curiosity Daily on your favorite podcast app to learn something new every day withCody Gough andAshley Hamer. Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. See omnystudio.com/listener for privacy information.

No matter how hard you try, it can often feel like your fitness isn't improving. It's so disappointing when you've been doing the same workouts over and over and you don't see any progress in your strength, or number of reps, or cardiovascular fitness. Even when you've been consistent with your exercise, sometimes it feels like you've hit a wall and you can't get past it. So what do you do when your progress has stalled? Gab and Sarah explain how to reframe the way you measure progress, and look for the many ways you are making headway (even when it doesn't feel like it). Don't forget to subscribe to the Women Like You newsletter. To be added to the mailing list, email womenlikeyoupodcast@gmail.com  WLY resources and recommendations: Sports Bras Direct Yoga With Adriene Morning Yoga Flow (22mins) Nike Run Club ‘Don't Wanna Run Run' WLY Spotify playlist Over Ear Earbuds (example only - we have not tried this particular brand) MadFit low Impact FULL BODY HIIT Workout (No Equipment + No Jumping) The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

The group is joined by Etienne Fontan and Sabrina Fendrick of Berkeley Patients Group (BPG) where they serve as the Vice President and Chief Public Affairs Officer (and part time miracle worker) respectively. We discuss cannabidiol (CBD) and the liver, Vice's coverage of the drug PCP, and a commentary article about trends in psychedelics use between women and men. Highlights of the episode include our lively discussion about Delta-8-THC, and a published study exploring physical health and lifetime psychedelic use. Be sure to stick around for the game at the end of the show, and test your cannabis trivia, with “guess which politician was high when they said this”.Thank you to the episode's sponsor Psilera - bringing a new era in mindful medicine.Episode's Group:Jahan Marcu, PhD (Moderator) Etienne FontanSabrina FendrickDavid Vaillencourt Nigam B. Arora, PhDNews and Popular Literature Links: CBD Safe for Liver, End of the Story? (2:37)PCP was Developed as a Pharmaceutical but Now is Only Used as an Illicit Drug: Let's compare it to ketamine (13:55)“You Can't Regulate What You Don't Test For”: Delta-8-THC in the news (25:15)Secondary source - https://ktvz.com/news/oregon-northwest/2021/03/20/olcc-to-limit-use-of-delta-8-thc-other-artificially-derived-cannabinoids/Report Shows Women More Likely to Use Psychedelics than Men (44:03)Rapid Fire Science Study Links:Cannabinoids, Endocannabinoids, and Sleep (2020).(53:28)Associations of Lifetime Psychedelic Use and Markers of Physical Health(1:09:30)Secondary Source - https://www.psypost.org/2021/03/psychedelic-drug-users-tend-to-have-better-overall-physical-health-than-non-users-study-finds-60021Today's Game: Check out the new game, called “guess which politician was high when they said this”. (1:22:15) Credits:Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Lovii Arora, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode. More at: howtolaunchanindustry.com marcu-arora.com

~ Explore the role of the endocannabinoid system in ~ Mood disorders ~ Cognitive disorders ~ Autoimmune and inflammatory disorders ~ Pain ~ Stress Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Greg Gerdeman, PhD, is a pioneer in researching the endocannabinoid system's physiology. In this episode, he describes cannabinoids as the 'first responders' of herbal medicine. Greg researched the ECS for over 20 years, and talks about cannabis as a gateway to understanding the roots of our biological evolution and how we can learn to change our health's narrative with this knowledge. He clears up over-simplifications of the ECS, which he sees as a complex conductor of a ‘symphony of biological interaction.' Common misinformation is spread unwittingly through popular demand for sound-byte explanations. As a Ph.D. student, he discovered that endocannabinoids act as "retrograde messengers" to regulate synaptic plasticity in the brain, findings that have become foundational to a modern understanding of the ECS and the neuroprotective actions of cannabinoids. He later co-directed research on exercise-mediated endocannabinoid signaling, revealing new insights into the "runner's high" and its evolutionary roles in exercise's neurological benefits. As a college professor, his lab focused on the ancient evolutionary origins of cannabinoid receptors. Upon co-founding a medical cannabis company in Florida, he directed scientific activities at every level of the supply chain, ranging from integrative pest management to product development to physician education. He is Chief Scientific Officer of UCANN and a voluntary Assistant Professor at the USF College of Pharmacy. Instagram quotes: "The endocannabinoid system has liberated cannabis from the drug abuse paradigm into the wellness paradigm. " Cannabis Voices Cannabis Voices, May 2020 Greg Gerdeman ECSMin 103:12. Personalized medicine and testing to help targeted approaches.Useful linksFacebook: https://www.facebook.com/DrGerdeman/instagram: https://www.instagram.com/ganjanesh/Research, articles and books as referenced within this podcast.https://www.projectcbd.org/science/brain-science-endocannabinoid-system-greg-gerdemanprojectcbd.org/science/endocannabinoid-system-and-biology-wellnesshttps://www.researchgate.net/profile/Gregory_Gerdemanhttps://www.researchgate.net/publication/226385957_The_Endocannabinoid_System_in_the_Physiology_and_Pathology_of_the_Basal_Gangliahttps://www.researchgate.net/publication/227031210_Endocannabinoids_at_the_Synapse_Retrograde_Signaling_and_Presynaptic_Plasticity_in_the_Brainhttps://www.amazon.com/Healing-Cannabis-Evolution-Endocannabinoid-Cannabinoids/dp/1510751866To learn more about plants & your health from Colleen at LabAroma check out this informative PDF: https://mailchi.mp/2fe0e426b244/osw1lg2dkhDisclaimer: The information presented in this podcast is for educational purposes only and is not intended to replace professional medical advice. Please consult your doctor if you are in need of medical care, and before making any changes to your health routine.

The cannabis that most people have access to isn't what it could be. A big part of that is a result of the way the plant has been bred to have high THC levels for the recreational market over the years."For the most part, around the world, we're still dealing with cannabis that is mostly high THC and high myrcene, which is gonna be very sedating, producing what we call colloquially couch lock, where the person feels immobilized," Dr. Ethan Russo explains on The Cannabis Enigma podcast. "So that might be fine for the person that's trying to get to sleep, but it's not at all good for the person that might need to work, or study, and function well in the process, and particularly for chronic pain conditions."Science has made great advances in identifying what chemical properties of a given cannabis chemovar would be beneficial for various diseases and treatments, "but that's a far cry from saying that they would be able to access a chemical variety of cannabis that would be appropriate for their treatment," Russo explains."We really haven't seen the capabilities of cannabis properly harnessed at this point," he adds.Dr. Russo, one of the premier cannabis researchers who is responsible for the theory of clinical endocannabinoid deficiency and has done a great deal of work on proving and harnessing the entourage effect, also discussed different approaches to dosing, and why developing a tolerance can actually be a good thing."The beauty of cannabis is, even though one gets accustomed to the psychoactive effects, the benefits on whatever you're treating remain. In other words, if we have a chronic pain patient and they get benefit from using cannabis, as long as that condition is stable — it's not getting worse — we don't see dose escalation over time, and in fact, there are many people, who have taken cannabis therapeutically for decades that are using the same dose."Dr. Russo will be speaking at the Whole Plant Expo.In the second part of the episode, Dustin McDonald of Americans for Safe Access interviews Sue Lewtin, a medical cannabis patient treating lyme disease, about her journey with the plant. Like so many others, Lewtin explains how her doctors got her started on the path of medical cannabis but that bulk of the work and learning had to be done on her own.Edited and mixed by Michael Schaeffer Omer-Man. Produced by Michael Schaeffer Omer-Man and Matan Weil. Music by Desca. The Cannabis Enigma podcast is a co-production of The Cannigma and Americans for Safe Access.

In the ancient teachings of Indian spirituality there was a distinction between the true yogi who lived a disciplined life to achieve enlightenment versus the fake yogi who tried to take shortcuts through drugs and indolence. ***** Website: https://Shiv..

Come listen and join the fun while we have a conversation with Guest expert Linda Palmer, exploring the realms of philosophy, neuroscience, and a few other interesting pathways. #philosophy #neuroscience #limbicsystem   T H E A U T H E N T I C I T Y S H O W real people | authentic […]

Gooey Rabinski is a prolific writer on the health benefits of cannabis. He joins Ian and Corrie to talk about his work and the wonders of cannabinoids in the human body.