Podcasts about diagnostic accuracy

En este episodio nos adentramos en uno de los territorios más complejos del sistema nervioso periférico adulto: las plexopatías braquiales. ¿Qué significa realmente que el plexo se lesione? ¿Es solo un cable roto o algo mucho más complejo? Exploramos cómo se organiza un nervio, qué ocurre en lesiones por tracción, compresión o inflamación y por qué muchas plexopatías son auténticos mosaicos intraneurales. Revisamos las clasificaciones de Seddon, Sunderland, el grado VI de Mackinnon y la clasificación quirúrgica por niveles de Chuang, entendiendo que no es solo anatomía, sino estrategia y pronóstico. Hablamos de degeneración Walleriana, regeneración axonal, diferencias entre lesiones pre y postganglionares, prioridades reconstructivas y del papel clave de la neurorrehabilitación tras las transferencias nerviosas. Porque integrar cirugía, electrodiagnóstico y rehabilitación es esencial para comprender realmente el plexo braquial desde una mirada clínica y neurofisiológica. Referencias del episodio: 1. Baradaran, A., El-Hawary, H., Efanov, J. I., & Xu, L. (2021). Peripheral Nerve Healing: So Near and Yet So Far. Seminars in plastic surgery, 35(3), 204–210. https://doi.org/10.1055/s-0041-1731630 (https://pubmed.ncbi.nlm.nih.gov/34526869/). 2. Chaudhry, V., & Cornblath, D. R. (1992). Wallerian degeneration in human nerves: serial electrophysiological studies. Muscle & nerve, 15(6), 687–693. https://doi.org/10.1002/mus.880150610 (https://pubmed.ncbi.nlm.nih.gov/1324426/). 3. Chim, H., & Hagan, R. R. (2024). Consensus Recommendations for Neurogenic Thoracic Outlet Syndrome from the INTOS Workgroup. Plastic and reconstructive surgery. Global open, 12(8), e6107. https://doi.org/10.1097/GOX.0000000000006107 (https://pubmed.ncbi.nlm.nih.gov/39206209/). 4. Chuang D. C. (2010). Brachial plexus injury: nerve reconstruction and functioning muscle transplantation. Seminars in plastic surgery, 24(1), 57–66. https://doi.org/10.1055/s-0030-1253242 (https://pmc.ncbi.nlm.nih.gov/articles/PMC2887004/). 5. Fisher, S., Wadhwa, V., Manthuruthil, C., Cheng, J., & Chhabra, A. (2016). Clinical impact of magnetic resonance neurography in patients with brachial plexus neuropathies. The British journal of radiology, 89(1067), 20160503. https://doi.org/10.1259/bjr.20160503 (https://pubmed.ncbi.nlm.nih.gov/27558928/). 6. Grinsell, D., & Keating, C. P. (2014). Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies. BioMed research international, 2014, 698256. https://doi.org/10.1155/2014/698256 (https://pubmed.ncbi.nlm.nih.gov/25276813/). 7. Massie, R., Mauermann, M. L., Staff, N. P., Amrami, K. K., Mandrekar, J. N., Dyck, P. J., Klein, C. J., & Dyck, P. J. (2012). Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies. Brain : a journal of neurology, 135(Pt 10), 3074–3088. https://doi.org/10.1093/brain/aws244 (https://pubmed.ncbi.nlm.nih.gov/23065793/). 8. Novak C. B. (2008). Rehabilitation following motor nerve transfers. Hand clinics, 24(4), 417–vi. https://doi.org/10.1016/j.hcl.2008.06.001 (https://pubmed.ncbi.nlm.nih.gov/18928890/). 9. Larkin, M. B., Goethe, E. A., Mohammad, M., Tummala, S., & North, R. Y. (2023). Ulnar fascicle to brachialis branch of musculocutaneous nerve for restoration of elbow flexion associated with spinal cord tumor and radiation-induced lower motor neuron disease. Neurosurgical focus: Video, 8(1), V9. https://doi.org/10.3171/2022.10.FOCVID2299 (https://pubmed.ncbi.nlm.nih.gov/36628102/). 10. Ray, W. Z., & Mackinnon, S. E. (2010). Management of nerve gaps: autografts, allografts, nerve transfers, and end-to-side neurorrhaphy. Experimental neurology, 223(1), 77–85. https://doi.org/10.1016/j.expneurol.2009.03.031 (https://pubmed.ncbi.nlm.nih.gov/19348799/). 11. Rocks, M. C., Comunale, V., Sanchez-Navarro, G. E., Nicholas, R. S., Hacquebord, J. H., & Adler, R. S. (2025). Diagnostic Capability of Ultrasonography in Evaluating Peripheral Nerve Injuries of the Brachial Plexus. Hand (New York, N.Y.), 20(8), 1252–1258. https://doi.org/10.1177/15589447241277844 (https://pubmed.ncbi.nlm.nih.gov/39289880/). 12. Rubin D. I. (2020). Brachial and lumbosacral plexopathies: A review. Clinical neurophysiology practice, 5, 173–193. https://doi.org/10.1016/j.cnp.2020.07.005 (https://pubmed.ncbi.nlm.nih.gov/32954064/). 13. Sakellariou, V. I., Badilas, N. K., Mazis, G. A., Stavropoulos, N. A., Kotoulas, H. K., Kyriakopoulos, S., Tagkalegkas, I., & Sofianos, I. P. (2014). Brachial plexus injuries in adults: evaluation and diagnostic approach. ISRN orthopedics, 2014, 726103. https://doi.org/10.1155/2014/726103 (https://pubmed.ncbi.nlm.nih.gov/24967130/). 14. Schierle, C., & Winograd, J. M. (2004). Radiation-induced brachial plexopathy: review. Complication without a cure. Journal of reconstructive microsurgery, 20(2), 149–152. https://doi.org/10.1055/s-2004-820771 (https://pubmed.ncbi.nlm.nih.gov/15011123/). 15. Segal, D., Cornwall, R., & Little, K. J. (2019). Outcomes of Spinal Accessory-to-Suprascapular Nerve Transfers for Brachial Plexus Birth Injury. The Journal of hand surgery, 44(7), 578–587. https://doi.org/10.1016/j.jhsa.2019.02.004 (https://pubmed.ncbi.nlm.nih.gov/30898464/). 16. Sturma, A., Hruby, L. A., Farina, D., & Aszmann, O. C. (2019). Structured Motor Rehabilitation After Selective Nerve Transfers. Journal of visualized experiments : JoVE, (150), 10.3791/59840. https://doi.org/10.3791/59840 (https://pubmed.ncbi.nlm.nih.gov/31475970/). 17. Tjoumakaris, F. P., Anakwenze, O. A., Kancherla, V., & Pulos, N. (2012). Neuralgic amyotrophy (Parsonage-Turner syndrome). The Journal of the American Academy of Orthopaedic Surgeons, 20(7), 443–449. https://doi.org/10.5435/JAAOS-20-07-443 (https://pubmed.ncbi.nlm.nih.gov/22751163/). 18. Vancea, C. V., Hodea, F. V., Bordeanu-Diaconescu, E. M., Cacior, S., Dumitru, C. S., Ratoiu, V. A., Stoian, A., Lascar, I., & Zamfirescu, D. (2025). Functional outcomes following nerve transfers for shoulder and elbow reanimation in brachial plexus injuries: a 10-year retrospective study. Journal of medicine and life, 18(4), 375–386. https://doi.org/10.25122/jml-2025-0079 (https://pubmed.ncbi.nlm.nih.gov/40405933/). 19. Van Eijk, J. J., Groothuis, J. T., & Van Alfen, N. (2016). Neuralgic amyotrophy: An update on diagnosis, pathophysiology, and treatment. Muscle & nerve, 53(3), 337–350. https://doi.org/10.1002/mus.25008 (https://pubmed.ncbi.nlm.nih.gov/26662794/). 20. Wade, R. G., Takwoingi, Y., Wormald, J. C. R., Ridgway, J. P., Tanner, S., Rankine, J. J., & Bourke, G. (2019). MRI for Detecting Root Avulsions in Traumatic Adult Brachial Plexus Injuries: A Systematic Review and Meta-Analysis of Diagnostic Accuracy. Radiology, 293(1), 125–133. https://doi.org/10.1148/radiol.2019190218 (https://pubmed.ncbi.nlm.nih.gov/31429680/). 21. Willmott, A. D., White, C., & Dukelow, S. P. (2012). Fibrillation potential onset in peripheral nerve injury. Muscle & nerve, 46(3), 332–340. https://doi.org/10.1002/mus.23310 (https://pubmed.ncbi.nlm.nih.gov/22907222/).

Where did arbitrary cut scores for norm-referenced language assessments come from, and why do they feel “safer” than relying on clinical judgement?I discuss this question and more in this third part of a three-part series, bilingual SLPs Destiny Johnson and Tiffany Shahoumian-Ruiz join me to continue our conversation about advocating for effective language evaluation practices in schools.Across these conversations, we explore:Sensitivity, specificity, reference standards, and diagnostic accuracyHow test development has evolved over time and why this matters Why the same cut-off score shouldn't apply across all testsThe math behind using two norm-referenced tests, and why it may complicate rather than clarify in some casesOther reasons we test beyond diagnosis (treatment planning, severity, monitoring progress)How do we do we to “sell” the concept of dynamic assessment to administratorsCase studies that show the pitfalls of over-reliance on standardized scoresMisconceptions clinicians often hold, and what they should know about assessmentDifferences in state eligibility standards, and what this means for service decisionsThis series is part myth-busting, part practical strategies, and part advocacy playbook—perfect for clinicians who want to move beyond compliance-driven evaluations toward assessments that truly reflect students' needs.Destiny Johnson, M.S., CCC-SLP, is a bilingual speech-language pathologist (English/Spanish) with a deep passion for culturally responsive assessment and treatment practices, as well as advocating for policy change. She has presented on dynamic assessment at the CSHA Convergence 2024, focusing on the importance of dynamic assessment in bilingual children. Destiny has experience working as a school-based SLP, in private practice, and in early intervention. She is also the founder and CEO of Multimodal Communication Speech Clinic P.C.Connect with Destiny on Instagram @destinyjohnsonslp, on her private practice website here, and on LinkedIn here.Listen to Destiny's previous episode on De Facto Leaders here: EP 187: Dynamic Assessment: Evaluations are a process, not a test (with Destiny Johnson)Tiffany Shahoumian-Ruiz is a bilingual high school SLP from Southern California who has primarily worked in the school systems and has experience at both the elementary and secondary level. She's also a member of Language Therapy Advance Foundations, and is involved in state and local advocacy work relating to dynamic assessments and special education eligibility.Connect with Tiffany on Instagram @tiffany.shahoumianListen to Tiffany's previous episode on De Facto Leaders here: High school language therapy: Do we still have time to make an impact? (with Tiffany Shahoumian-Ruiz)In this episode, I mention Language Therapy Advance Foundations, my program that gives SLPs and other service providers a system for language therapy. You can learn more about the program here.Additional Resources Mentioned in the episode:Daub, O., Cunningham, B. J., Bagatto, M. P., Johnson, A. M., Kwok, E. Y., Smyth, R. E., & Oram Cardy, J. (2021). Adopting a conceptual validity framework for testing in speech-language pathology. American Journal of Speech-Language Pathology, 30(4), 1894–1908. https://doi.org/10.1044/2021_AJSLP-20-00032Spaulding, T. J., Plante, E., & Farinella, K. A. (2006). Eligibility criteria for language impairment: Is the low end of normal always appropriate? Language, Speech, and Hearing Services in Schools, 37(1), 61–72. https://doi.org/10.1044/0161-1461(2006/007)DYMOND Norm-Referenced Dynamic AssessmentBilingual English-Spanish Assessment (BESA) We're thrilled to be sponsored by IXL. IXL's comprehensive teaching and learning platform for math, language arts, science, and social studies is accelerating achievement in 95 of the top 100 U.S. school districts. Loved by teachers and backed by independent research from Johns Hopkins University, IXL can help you do the following and more:Simplify and streamline technologySave teachers' timeReliably meet Tier 1 standardsImprove student performance on state assessments

When we choose evaluation tools for language, are we clear on WHY we're assessing? Most people think of diagnosis, but that's not the only reason we assess students. I discuss this question and more in this second part of a three-part series, bilingual SLPs Destiny Johnson and Tiffany Shahoumian-Ruiz join me to continue our conversation about language evaluation practices in schools.Across these conversations, we explore:Sensitivity, specificity, reference standards, and diagnostic accuracyHow test development has evolved over time and why this matters Why the same cut-off score shouldn't apply across all testsThe math behind using two norm-referenced tests, and why it may complicate rather than clarify in some casesOther reasons we test beyond diagnosis (treatment planning, severity, monitoring progress)How do we do we to “sell” the concept of dynamic assessment to administratorsCase studies that show the pitfalls of over-reliance on standardized scoresMisconceptions clinicians often hold, and what they should know about assessmentDifferences in state eligibility standards, and what this means for service decisionsThis series is part myth-busting, part practical strategies, and part advocacy playbook—perfect for clinicians who want to move beyond compliance-driven evaluations toward assessments that truly reflect students' needs.Destiny Johnson, M.S., CCC-SLP, is a bilingual speech-language pathologist (English/Spanish) with a deep passion for culturally responsive assessment and treatment practices, as well as advocating for policy change. She has presented on dynamic assessment at the CSHA Convergence 2024, focusing on the importance of dynamic assessment in bilingual children. Destiny has experience working as a school-based SLP, in private practice, and in early intervention. She is also the founder and CEO of Multimodal Communication Speech Clinic P.C.Connect with Destiny on Instagram @destinyjohnsonslp, on her private practice website here, and on LinkedIn here.Listen to Destiny's previous episode on De Facto Leaders here: EP 187: Dynamic Assessment: Evaluations are a process, not a test (with Destiny Johnson)Tiffany Shahoumian-Ruiz is a bilingual high school SLP from Southern California who has primarily worked in the school systems and has experience at both the elementary and secondary level. She's also a member of Language Therapy Advance Foundations, and is involved in state and local advocacy work relating to dynamic assessments and special education eligibility.Connect with Tiffany on Instagram @tiffany.shahoumianListen to Tiffany's previous episode on De Facto Leaders here: High school language therapy: Do we still have time to make an impact? (with Tiffany Shahoumian-Ruiz)In this episode, I mention Language Therapy Advance Foundations, my program that gives SLPs and other service providers create a system for language therapy. You can learn more about the program here.Additional Resources Mentioned in the episode:Daub, O., Cunningham, B. J., Bagatto, M. P., Johnson, A. M., Kwok, E. Y., Smyth, R. E., & Oram Cardy, J. (2021). Adopting a conceptual validity framework for testing in speech-language pathology. American Journal of Speech-Language Pathology, 30(4), 1894–1908. https://doi.org/10.1044/2021_AJSLP-20-00032Spaulding, T. J., Plante, E., & Farinella, K. A. (2006). Eligibility criteria for language impairment: Is the low end of normal always appropriate? Language, Speech, and Hearing Services in Schools, 37(1), 61–72. https://doi.org/10.1044/0161-1461(2006/007)DYMOND Norm-Referenced Dynamic AssessmentBilingual English-Spanish Assessment (BESA) We're thrilled to be sponsored by IXL. IXL's comprehensive teaching and learning platform for math, language arts, science, and social studies is accelerating achievement in 95 of the top 100 U.S. school districts. Loved by teachers and backed by independent research from Johns Hopkins University, IXL can help you do the following and more:Simplify and streamline technologySave teachers' timeReliably meet Tier 1 standardsImprove student performance on state assessments

In this episode of the ESCRS IME podcast series on simultaneous vision IOLs, Drs. Francesco Carones and Andrea Janeková explain why a healthy ocular surface is essential before cataract refractive surgery. Even mild dry eye can skew keratometry readings and IOL calculations—yet it's often overlooked. Left untreated, dry eye can cause refractive surprises and postoperative dissatisfaction. The experts stress a thorough ocular surface evaluation and show how treating dry eye beforehand ensures more accurate results, better outcomes, and happier patients. Don't miss this insightful episode and be sure to check out the other expert-led podcasts in the series! Independent medical education supported by Alcon (Gold), J&J (Gold), B+L (Silver), Zeiss (Bronze).

Language assessments shape who gets services, how goals are written, and how progress is measured, but there are many misconceptions about how to follow best-practices when doing an evaluation. In this three-part series, bilingual SLPs Destiny Johnson and Tiffany Shahoumian-Ruiz join me to dig into the science, the myths, and the policies that shape evaluation practices in schools.Across these conversations, we explore:Sensitivity, specificity, reference standards, and diagnostic accuracyHow test development has evolved over time and why this matters Why the same cut-off score shouldn't apply across all testsThe math behind using two norm-referenced tests, and why it may complicate rather than clarify in some casesOther reasons we test beyond diagnosis (treatment planning, severity, monitoring progress)How do we do we to “sell” the concept of dynamic assessment to administratorsCase studies that show the pitfalls of over-reliance on standardized scoresMisconceptions clinicians often hold, and what they should know about assessmentDifferences in state eligibility standards, and what this means for service decisionsThis series is part myth-busting, part practical strategies, and part advocacy playbook—perfect for clinicians who want to move beyond compliance-driven evaluations toward assessments that truly reflect students' needs.You can listen to Part 1 of the series here.Destiny Johnson, M.S., CCC-SLP, is a bilingual speech-language pathologist (English/Spanish) with a deep passion for culturally responsive assessment and treatment practices, as well as advocating for policy change. She has presented on dynamic assessment at the CSHA Convergence 2024, focusing on the importance of dynamic assessment in bilingual children. Destiny has experience working as a school-based SLP, in private practice, and in early intervention. She is also the founder and CEO of Multimodal Communication Speech Clinic P.C.Connect with Destiny on Instagram @destinyjohnsonslp, on her private practice website here, and on LinkedIn here.Listen to Destiny's previous episode on De Facto Leaders here: EP 187: Dynamic Assessment: Evaluations are a process, not a test (with Destiny Johnson)Tiffany Shahoumian-Ruiz is a bilingual high school SLP from Southern California who has primarily worked in the school systems and has experience at both the elementary and secondary level. She's also a member of Language Therapy Advance Foundations, and is involved in state and local advocacy work relating to dynamic assessments and special education eligibility.Connect with Tiffany on Instagram @tiffany.shahoumianListen to Tiffany's previous episode on De Facto Leaders here: High school language therapy: Do we still have time to make an impact? (with Tiffany Shahoumian-Ruiz)In this episode, I mention Language Therapy Advance Foundations, my program that gives SLPs and other service providers create a system for language therapy. You can learn more about the program here.Additional Resources Mentioned in the episode:Daub, O., Cunningham, B. J., Bagatto, M. P., Johnson, A. M., Kwok, E. Y., Smyth, R. E., & Oram Cardy, J. (2021). Adopting a conceptual validity framework for testing in speech-language pathology. American Journal of Speech-Language Pathology, 30(4), 1894–1908. https://doi.org/10.1044/2021_AJSLP-20-00032Spaulding, T. J., Plante, E., & Farinella, K. A. (2006). Eligibility criteria for language impairment: Is the low end of normal always appropriate? Language, Speech, and Hearing Services in Schools, 37(1), 61–72. https://doi.org/10.1044/0161-1461(2006/007)DYMOND Norm-Referenced Dynamic AssessmentBilingual English-Spanish Assessment (BESA) We're thrilled to be sponsored by IXL. IXL's comprehensive teaching and learning platform for math, language arts, science, and social studies is accelerating achievement in 95 of the top 100 U.S. school districts. Loved by teachers and backed by independent research from Johns Hopkins University, IXL can help you do the following and more:Simplify and streamline technologySave teachers' timeReliably meet Tier 1 standardsImprove student performance on state assessments

Visual Expertise and Diagnostic Accuracy with Claudia Mello-Thoms, PhDIn this episode of The Girl Doc Survival Guide, Christine interviews Claudia Mello-Thoms, PhD, an Associate Professor of Radiology and Biomedical Engineering at the University of Iowa. Claudia discusses her research on visual search, medical image perception, and why errors occur in reading radiological images. Key topics include the use of eye tracking to detect unconscious viewing patterns, the different diagnostic approaches of experts and novices in pathology, and the concept of visual templates aiding rapid diagnosis. Claudia shares insights into how experts efficiently use low magnification to guide further detailed inspection, and the cognitive load differences between experienced and inexperienced diagnosticians.00:00 Introduction to Claudia Mello-Thoms00:47 Eye Tracking in Radiology02:12 Pathologists and Microscopic Slides06:56 Visual Search Strategies in Medical Imaging09:42 Expert vs. Novice: Cognitive Processes11:35 Templates and Rapid Recognition20:48 Conclusion and Next Episode Teaser

Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Robert Herman, MD, PhD discuss AI-Enabled ECG Analysis Improves Diagnostic Accuracy and Reduces False STEMI Activations: A Multicenter U.S. Registry, presented as a Late Breaking Clinical Trial at TCT 2025.

https://bit.ly/4mDRbKKAula de Laringoscopia: O passo a passo para fazer do jeito certo.

Send us a textDiagnostic accuracy of an over-the-counter infant pulse oximeter for cardiorespiratory events.Travers CP, Nakhmani A, Armstead KM, Benz RL, Foshee KM, Carlo WA.Arch Dis Child Fetal Neonatal Ed. 2025 May 12:fetalneonatal-2025-328540. doi: 10.1136/archdischild-2025-328540. Online ahead of print.PMID: 40355254As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode, Dr. Ashwin Singh Parihar is joined by Dr. Jelijn Knip and Dr. Willemien Menke to discuss their study comparing FDG PET and FES PET for staging grade 1 or 2 ER-positive breast cancer, highlighting how FES PET may offer more accurate results for certain tumors. Tune in to learn how these imaging techniques can impact treatment decisions. The Diagnostic Accuracy of 18F-FDG PET and 18F-FES PET for Staging Grade 1–2 Estrogen Receptor–Positive Breast Cancer. Knip and Iqbal et al. Radiology 2025; 314(3):e241850.

Guest: Andrew J. Solomon, MD Accurately diagnosing multiple sclerosis (MS) involves understanding the diagnostic criteria, recognizing red flags to avoid misdiagnosis, and keeping up with new tools. Dr. Andrew Solomon, Professor and Interim Chair of the Department of Neurological Sciences and Chief of the Multiple Sclerosis Division at the University of Vermont, walks through the most difficult aspects of diagnosing patients with MS and potential breakthroughs reshaping how we approach these challenges. Dr. Solomon also spoke about this topic at the 2025 American Academy of Neurology Annual Meeting.

Guest: Andrew J. Solomon, MD Accurately diagnosing multiple sclerosis (MS) involves understanding the diagnostic criteria, recognizing red flags to avoid misdiagnosis, and keeping up with new tools. Dr. Andrew Solomon, Professor and Interim Chair of the Department of Neurological Sciences and Chief of the Multiple Sclerosis Division at the University of Vermont, walks through the most difficult aspects of diagnosing patients with MS and potential breakthroughs reshaping how we approach these challenges. Dr. Solomon also spoke about this topic at the 2025 American Academy of Neurology Annual Meeting.

Guest: Andrew J. Solomon, MD Accurately diagnosing multiple sclerosis (MS) involves understanding the diagnostic criteria, recognizing red flags to avoid misdiagnosis, and keeping up with new tools. Dr. Andrew Solomon, Professor and Interim Chair of the Department of Neurological Sciences and Chief of the Multiple Sclerosis Division at the University of Vermont, walks through the most difficult aspects of diagnosing patients with MS and potential breakthroughs reshaping how we approach these challenges. Dr. Solomon also spoke about this topic at the 2025 American Academy of Neurology Annual Meeting.

Guest: Andrew J. Solomon, MD Accurately diagnosing multiple sclerosis (MS) involves understanding the diagnostic criteria, recognizing red flags to avoid misdiagnosis, and keeping up with new tools. Dr. Andrew Solomon, Professor and Interim Chair of the Department of Neurological Sciences and Chief of the Multiple Sclerosis Division at the University of Vermont, walks through the most difficult aspects of diagnosing patients with MS and potential breakthroughs reshaping how we approach these challenges. Dr. Solomon also spoke about this topic at the 2025 American Academy of Neurology Annual Meeting.

Send us a textIn this episode of the Digital Pathology Podcast, I sit down with Matthew Nuñez, CEO of MUSE Microscopy, to discuss the groundbreaking advancements in direct-to-digital imaging in pathology. Traditional pathology workflows rely on glass slides, formalin fixation, and time-consuming processing steps. But what if we could skip the slide entirely and go straight to digital?

Dr. Linda Chu speaks with Dr. Daniele Andreini about the Advantage II Study, which evaluates the accuracy of dynamic stress myocardial CT perfusion in patients with coronary artery stents. They discuss how this technique compares to invasive testing, its advantages over static CT perfusion, and its impact on cardiac imaging. Diagnostic Accuracy of Dynamic Stress Myocardial CT PerfusionCompared with Invasive Physiology in Patients with Stents:The Advantage 2 Study. Andreini and Mushtaq et al. Radiology 2024; 313(3):e232225.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Diagnostic Accuracy of Apple Watch Electrocardiogram for Atrial Fibrillation: A Systematic Review and Meta-Analysis

Advancements in artificial intelligence are transforming healthcare, and remote cardiac monitoring is at the forefront of this change. With cardiovascular disease impacting nearly 50% of the population at some point in their lives, early detection and efficient diagnosis are crucial. Enter AI-powered cardiac monitors that provide near real-time data, reduce diagnostic errors, and improve access to care. But how exactly does this technology work, and what does it mean for patients and healthcare providers?Welcome to I Don't Care. In this episode, Dr Kevin Stevenson sits down with Stuart Long, the CEO of InfoBionic.AI, to explore the transformative impact of AI on cardiac monitoring. From continuous monitoring that detects arrhythmias in real-time to algorithms developed in collaboration with Mayo Clinic, this conversation addresses a vital question: How can technology redefine the landscape of cardiac care?Key Points of Discussion:Continuous Monitoring Revolution: InfoBionic's device streams data to the cloud, using AI to process millions of heartbeats and prioritize critical information for physicians.Reducing False Positives: By leveraging advanced AI and signal processing, the company has reduced false positives for atrial fibrillation by over 85%, providing clinicians with cleaner, more actionable data.Improving Health Equity: With remote cardiac monitoring solutions that eliminate the need for in-person visits, InfoBionic ensures greater access to cardiac care, especially in rural areas.Stuart Long is a seasoned healthcare executive with over 30 years of experience leading and scaling companies in the medical device and healthcare IT sectors. As CEO of InfoBionic.AI, he has pioneered advancements in AI-powered cardiac monitoring, significantly improving diagnostic accuracy and patient outcomes. With expertise in enterprise software, medical imaging, and strategic operations, Long also brings a strong background in marketing strategy, honed at Cornell University's Johnson Graduate School of Management.

Are you frustrated with patient positioning during video fluoroscopy studies? Ever wonder why some facilities seem to breeze through MBS studies while others struggle to get basic views? This week's episode might just change how you think about your fluoroscopy equipment forever. We're thrilled to share our conversation with Julie Kobak, MA, CCC-SLP, CBIS, a […] The post 353 – Why Your MBS Chair Could Make or Break Your Diagnostic Accuracy with Julie Kobak MA, CCC-SLP, CBIS appeared first on Swallow Your Pride Podcast.

In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Jeffrey Stringer, MD, University of North Carolina, joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss "Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps." Related Content: The Low-Cost, Battery-Powered AI-Enabled Ultrasound Device That Could Improve Global Obstetric Care Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps

In the October 2024 replay features four episodes on approaches to clinical diagnosis of parkinsonism. The episode starts off with Dr. Colin Hoy discuss the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis. The episode leads into a conversation with Dr. Chris Gibbons discussing skin biopsies to detect phosphorylated α-synuclein. In the third episode Drs. Michiko K. Bruno and Lawrence Golbe about a practical diagnostic algorithm for atypical parkinsonian disorders Drs. Michiko K. Bruno and Lawrence Golbe discuss a practical diagnostic algorithm for atypical parkinsonian disorders. The episode concludes with Dr. Eduardo De Pablo-Fernández talking about the strengths of DAT imaging in diagnosing patients with Parkinsonian disorders. Previous Podcasts: The Ethical Landscape of Prodromal Parkinson Disease Skin Biopsy Detection of Phosphorylated α-Synuclein General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders Interpreting DAT Imaging Results in the Clinical Context Article Links: The Ethical Landscape of Prodromal Parkinson Disease  Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders  Neuropathologic Validation and Diagnostic Accuracy of Presynaptic Dopaminergic Imaging in the Diagnosis of Parkinsonism Disclosures can be found at Neurology.org.

Date: September 23, 2024 Reference: Essat et al. Diagnostic Accuracy of D-Dimer for Acute Aortic Syndromes: Systematic Review and Meta-Analysis. Annals of Emergency Medicine, May 2024 Guest Skeptic: Dr. Casey Parker is a Rural Generalist from Australia who is also an ultrasounder. Case: You are working a busy shift in a rural emergency department (ED) […] The post SGEM#454: I Just Died in Your Arms Tonight – Diagnostic Accuracy of D-Dimer for Acute Aortic Syndromes first appeared on The Skeptics Guide to Emergency Medicine.

Gestational age estimation is foundational for obstetric care. In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Author Jeffrey Stringer, MD, University of North Carolina, joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps. Related Content: Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps Enhancing Obstetric Ultrasonography With Artificial Intelligence in Resource-Limited Settings

Rebecca Le, MD discusses an article detailing how core needle biopsy may help avoid a missed or delayed cancer diagnosis in pulmonary lesions with cystic airspaces. ARTICLE TITLE - CT-Guided Core-Needle Biopsy of Pulmonary Lesions Associated With Cystic Airspaces: A Case-Control Study

Kaele M. Leonard, MD, and Robert J. Lentz, MD, join CHEST Podcast Moderator Dominique Pepper, MD, to discuss whether a conservative diagnostic yield definition may represent a useful outcome for future studies of diagnostic utility.

In this installment of "The Jaded Mechanic," Jeff Compton welcomes Zeb Beard, a revered figure in the automotive service industry. Zeb underscores the importance of accurate diagnostics, sharing that a two-hour diagnostic base not only bolsters customer trust but also underpins the financial health of the shop. Zeb also highlights his unique customer service philosophy, stressing the benefits of serving premium customers who rely on his expertise without second-guessing his decisions. Throughout the episode, both Jeff and Zeb delve into their regional differences in vehicle maintenance needs, with a particular focus on the challenges posed by rust and its influence on repair strategies.00:00 Vehicle maintenance and undercoating for older trucks.04:43 Challenges with Subaru and Ford wheel bearings.07:10 Road brine corrodes trucks and harms the environment.11:01 Refreshing to converse with a confident, like-minded peer.13:13 Struggling business owners seek simplicity and guidance.17:25 Guiding others through learning from past mistakes.21:35 Surprised by new lab scope test method.25:54 Intermittent issues and customer choices in repairs.26:50 Customer understanding through detailed explanation and demonstration.32:11 Customers can attract a new type of clientele.33:19 Prefers customers who seek personalized service.36:48 Building shop, need staff, reducing spending. Costly.40:24 Met in '98, married after a few months.44:07 Please like, comment, share, and download the podcast. Thanks to our sponsor Promotive! Find your dream job today: gopromotive.com/jeff 

DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.                                                  >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.                                                                                  Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Welcome back to "Ditch the Labcoat," where today we're diving deep with the compelling insights of Dr. James East. From intense medical shifts that demand lightning-fast responsiveness to the emotionally charged transitions from ICU pressures to family presence, Dr. East offers a rare window into the life-saving ballet performed daily by our healthcare heroes.Together, they shed light on the emotional fortitude required in this profession, the camaraderie needed to weather the storm, and the ever-evolving tools at their disposal.As the worlds of healthcare and technology collide, we explore the role of AI and technological interfaces, challenging the traditional white coat with terms like Chat GPT and electronic health records. Dr. East, a critical care maestro, and tech startup visionary, debates the true utility of inference-based decisions and AI-assisted diagnostics, while Dr. Bonta lends his seasoned skepticism to the conversation on tools like ECGs and their digital interpretations.From the lab to the living room, the discussion navigates the emotional labor physicians carry and the importance of processing traumatic cases. And as if navigating the corridors of care wasn't enough, our guests tackle the digital transformation of healthcare head-on, weighing in on the potential integration of AI in patient care and the necessity of maintaining the human touch amidst digital disruption.Strap in for a journey through the pulse-pounding, data-driven, and deeply human field of modern medicine. You don't need a lab coat where we're going—this is "Ditch the Labcoat," featuring Dr. James East.Dr. James East, GIM/ICU physician at Mackenzie Health and Trillium Health Partners. Chief Product Officer and Head of Content Development at FirstHx /  https://firsthx.com/about-us/Episode Timestamps :00:00 Doctor bridges clinical work with healthcare technology.10:16 Supportive partner helps balance demanding work schedule.13:33 Residency experience: few patients come home.18:43 Dealing with worst days, first responders' challenges.25:54 Advances in technology enhance clinical decision-making.27:13 Analyze electronic health records evolution from paper.36:55 AI engines lack meaningful benefits for clinicians.38:37 Need standardized, evidence-based, high-quality solutions for clinicians.48:06 AI can aid in efficient, thorough patient care.55:09 AI may struggle to replicate human empathy.59:16 Ethical concerns regarding AI in healthcare.01:05:11 Advocacy for seeking professional medical support online.01:09:04 AI aiding clinicians in diagnosing and treating.© 2024 ditchthelabcoat.com - All Rights Reserved 

Er wordt al jaren hard gewerkt aan een bloedtest voor het diagnosticeren van Alzheimer. Onderzoekers van een Zweedse Universiteit hebben één van de reeds ontwikkelde testen nu nader onderzocht. Hun conclusie: dit werkt evengoed als een ruggenprik of hersenscan. Omdat een ruggenprik invasief en onprettig is en een scan vaak enorm kostbaar, is de hoop dat een bloedtest een makkelijk en goedkoop alternatief is voor het stellen van de diagnose. Zeker als we ooit richting bevolkingsonderzoeken willen bewegen. Het uitvoerig bestuderen van ontwikkelde bloedtesten was nog moeilijk, omdat er vaak niet genoeg testen beschikbaar waren. Experts reageren hoopvol op een onderzoek waarin dat wel gelukt lijkt te zijn. Hierin werd gekeken naar een bestaande bloedtest die de aanwezigheid van het eiwit p-tau217 aantoont. Volgens de onderzoekers lukt het met de test evengoed als met een ruggenprik en zelfs beter dan met een scan om aan te tonen of er sprake van Alzheimer is. Het onderzoek zelf vind je hier: Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology Er werd onder andere hier over geschreven: Blood test could revolutionise diagnosis of Alzheimer's, experts say en hier New blood test that screens for Alzheimer's may be a step closer to reality, study suggests. Hier vind je meer info over ALZpath, het bedrijf achter de test.  See omnystudio.com/listener for privacy information.

In this episode of The FARM Cast, we delve into the intricate world of Carpal Tunnel Syndrome (CTS) – a condition that affects millions worldwide. Join us as we unravel the complexities of CTS, exploring its causes, symptoms, and potential treatments. Dr. Beau sheds light on the anatomy of the wrist, explaining how the carpal tunnel, a narrow passageway in the wrist, can become a source of discomfort and pain. We discuss the common risk factors associated with CTS, including repetitive hand movements, poor ergonomics, and certain medical conditions. Listeners will gain valuable insights into recognizing the early warning signs of CTS, such as tingling, numbness, and weakness in the hand and fingers. Our guest shares practical tips on ergonomics and exercises that can help prevent and alleviate symptoms, making this episode a must-listen for anyone spending extended hours on keyboards or engaging in repetitive hand activities. -- Abdalbary SA, Abdel-Wahed M, Amr S, Mahmoud M, El-Shaarawy EAA, Salaheldin S, Fares A. The Myth of Median Nerve in Forearm and Its Role in Double Crush Syndrome: A Cadaveric Study. Front Surg. 2021 Sep 21;8:648779. doi: 10.3389/fsurg.2021.648779. PMID: 34621777; PMCID: PMC8490666. Karne SS, Bhalerao NS. Carpal Tunnel Syndrome in Hypothyroidism. J Clin Diagn Res. 2016 Feb;10(2):OC36-8. doi: 10.7860/JCDR/2016/16464.7316. Epub 2016 Feb 1. PMID: 27042500; PMCID: PMC4800566. Kong G, Brutus JP, Vo TT, Hagert E. The prevalence of double- and multiple crush syndromes in patients surgically treated for peripheral nerve compression in the upper limb. Hand Surg Rehabil. 2023 Dec;42(6):475-481. doi: 10.1016/j.hansur.2023.09.002. Epub 2023 Sep 14. PMID: 37714514. Louie D, Earp B, Blazar P. Long-term outcomes of carpal tunnel release: a critical review of the literature. Hand (N Y). 2012 Sep;7(3):242-6. doi: 10.1007/s11552-012-9429-x. PMID: 23997725; PMCID: PMC3418353. Mills ES, Mertz K, Fresquez Z, Ton A, Buser Z, Alluri RK, Hah RJ. The Incidence of Double Crush Syndrome in Surgically Treated Patients. Global Spine J. 2022 Nov 1:21925682221137530. doi: 10.1177/21925682221137530. Epub ahead of print. PMID: 36321208. Möllestam K, Rosales RS, Lyrén PE, Atroshi I. Measuring symptoms severity in carpal tunnel syndrome: score agreement and responsiveness of the Atroshi-Lyrén 6-item symptoms scale and the Boston symptom severity scale. Qual Life Res. 2022 May;31(5):1553-1560. doi: 10.1007/s11136-021-03039-1. Epub 2021 Nov 20. PMID: 34800220; PMCID: PMC9023404. Mondelli M, Farioli A, Mattioli S, Aretini A, Ginanneschi F, Greco G, Curti S. Severity of Carpal Tunnel Syndrome and Diagnostic Accuracy of Hand and Body Anthropometric Measures. PLoS One. 2016 Oct 21;11(10):e0164715. doi: 10.1371/journal.pone.0164715. PMID: 27768728; PMCID: PMC5074522. Pensy RA, Burke FD, Bradley MJ, Dubin NH, Wilgis EF. A 6-year outcome of patients who cancelled carpal tunnel surgery. J Hand Surg Eur Vol. 2011 Oct;36(8):642-7. doi: 10.1177/1753193411410155. Epub 2011 Jun 2. PMID: 21636619. Rozmaryn LM, Dovelle S, Rothman ER, Gorman K, Olvey KM, Bartko JJ. Nerve and tendon gliding exercises and the conservative management of carpal tunnel syndrome. J Hand Ther. 1998 Jul-Sep;11(3):171-9. doi: 10.1016/s0894-1130(98)80035-5. PMID: 9730093. Sangram, B.S.; Mayne, A.I.W.; Jariwala, A.C. Can we accurately predict nerve conduction study outcome using a carpal tunnel syndrome questionnaire? Surgeon 2019, 17, 156–159. --- Send in a voice message: https://podcasters.spotify.com/pod/show/thefarmcast/message

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

Karen Pierce, Ph.D., explores using eye tracking to diagnose and treat autism. Her work identifies patterns in children's attention, aiming to streamline diagnosis, predict symptom severity, and tailor treatments. The focus is on early intervention by making social stimuli engaging for kids with varied attention patterns. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39170]

In this episode with Dr Chris Bleakley, we discuss his Research Review of a recent article looking at the Ottawa Ankle Rules. We discuss the components of the Ottawa Ankle Rules and how they can be used in your clinical practice to help guide your treatments. We also discuss the clinical accuracy of the Ottawa ankle rules and what the findings of this systematic review were. 

To close or not to close - that is the question!  Internal hernias following bariatric surgery can be a vexing source of delayed postoperative morbidity.  Join Drs. Matthew Martin, Kunoor Jain-Spangler, Adrian Dan, and Vincent Cheng for this EXCELLENT Journal Review in Bariatric Surgery.   Article #1: Stenberg 2023 - Long-term Safety and Efficacy of Closure of Mesenteric Defects in Laparoscopic Gastric Bypass Surgery Two mesenteric defects are created during Roux-en-Y gastric bypass (RNYGB) Petersen's Defect Jejuno-jejunostomy mesenteric defect  Consensus does not exist regarding the standard of care for mesenteric defect closure (e.g., closure of one or both defects, material used for closure).  Risks of leaving defects open: internal herniation with or without bowel ischemia  Risks of closing defects Kinking the bowel (especially near the jejunojejunostomy) leading to obstruction  Chronic abdominal pain This article discusses a randomized controlled trial of obese patients undergoing bariatric RNYGB Randomized into two groups: a closure group and a non-closure group  Followed patients for 10 years with 95-96% follow up rate Results analyzed using a Cox proportional hazards regression that included risk factors like BMI, total weight loss at 1 year after surgery, and the other  Highlighted outcomes  Within the first 30 postop days, there was a higher rate of SBO in the closure group (1.3%) compared to the non-closure group (0.2%). This was attributed to kinking of the jejunojejunostomy  After 30 postop days and up to 10 years, reoperation rates for SBO were higher in the non-closure group (14.9%) compared to the closure group (7.8%). This trend was consistent regarding each site of mesenteric defect.  No significant differences between the two groups regarding chronic opioid use as a metric of chronic abdominal pain. Article #2: Nawas 2022 - The Diagnostic Accuracy of Abdominal Computed Tomography in Diagnosing Internal Herniation Following Roux-en-Y Gastric Bypass Surgery Unless there is an indication to immediately operate on a RNYGB patient in whom internal herniation is suspected, computed tomography (CT) is the recommended diagnostic test This article is a meta-analysis of 20 studies published between 2007 and 2020 that analyzed the accuracy of CT or detecting internal hernias in adult patients who underwent RNYGB for morbid obesity. A collective total of 1,637 patients were included.   Accuracy was determined by comparing diagnostic CT with exploratory surgery or the combination of negative CT and a negative 90 days follow-up Internal herniation was defined as presence of herniated small bowel with or without obstruction or ischemia through a visible opening at the mesenteric defect Results Pooled sensitivity of CT was 82% and specificity was 85% Positive predictive value of CT was 83% and negative predictive value was 86% CT signs with the highest sensitivity (sensitivity of finding)  Venous congestion (79%) Swirl sign (78%)  Mesenteric edema (67%) 15% risk of an internal hernia even with a negative CT scan In conclusion, CT can provide useful information, but these are just additional data points to consider in the overall evaluation of a patient. Surgeons should still have a low threshold for diagnostic laparoscopy even with negative CT findings If you liked this episode, check out other bariatric episodes here: https://behindtheknife.org/podcast-category/bariatric/ Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  

Go online to PeerView.com/NEF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Alzheimer's disease (AD) is a devastating and highly prevalent condition, affecting 10% of people over 65 years of age, and increasing in prevalence as the population ages. Given the heavy economic and social burdens of AD, major emphasis has been placed on finding disease-modifying therapies (DMTs) that can address the underlying pathophysiology and prevent, delay, slow, or halt the inexorable decline of AD. Now, after almost two decades without a new AD treatment, recent advances in DMTs, including the accelerated approval from the FDA of two amyloid-targeting therapies (ATTs) and a third in late-stage development, have opened the door to the possibility of reductions in disease progression and improved patient outcomes. In order for these treatments to be successful, initiation in the prodromal or early symptomatic stages of AD is critical. Fortunately, significant advances have been made in the development and validation of molecular imaging techniques that may aid in an early diagnosis. It is therefore imperative that clinicians remain aware of the evolving role of molecular imaging tools (eg, amyloid PET, FDG PET, tau PET) and PET quantification techniques in the early diagnosis of AD, and are prepared to integrate these diagnostic tools into clinical practice. At a recent PeerView educational event, a panel of AD experts illustrated how to integrate validated and emerging neuroimaging biomarkers and quantitative measures into clinical practice to facilitate AD diagnosis. Through a case-based discussion, the faculty offered learners an in-depth look at the complex diagnostic challenges associated with early AD and mild cognitive impairment, and provided practical guidance on effectively and appropriately incorporating these strategies into patient care. You can now watch this on-demand version of the event! Upon completion of this activity, participants should be better able to: Employ molecular imaging tools to optimize the timely and accurate neuropathological diagnosis of AD; and Apply quantitative analysis to augment the visual interpretation of PET imaging in AD

Go online to PeerView.com/NEF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Alzheimer's disease (AD) is a devastating and highly prevalent condition, affecting 10% of people over 65 years of age, and increasing in prevalence as the population ages. Given the heavy economic and social burdens of AD, major emphasis has been placed on finding disease-modifying therapies (DMTs) that can address the underlying pathophysiology and prevent, delay, slow, or halt the inexorable decline of AD. Now, after almost two decades without a new AD treatment, recent advances in DMTs, including the accelerated approval from the FDA of two amyloid-targeting therapies (ATTs) and a third in late-stage development, have opened the door to the possibility of reductions in disease progression and improved patient outcomes. In order for these treatments to be successful, initiation in the prodromal or early symptomatic stages of AD is critical. Fortunately, significant advances have been made in the development and validation of molecular imaging techniques that may aid in an early diagnosis. It is therefore imperative that clinicians remain aware of the evolving role of molecular imaging tools (eg, amyloid PET, FDG PET, tau PET) and PET quantification techniques in the early diagnosis of AD, and are prepared to integrate these diagnostic tools into clinical practice. At a recent PeerView educational event, a panel of AD experts illustrated how to integrate validated and emerging neuroimaging biomarkers and quantitative measures into clinical practice to facilitate AD diagnosis. Through a case-based discussion, the faculty offered learners an in-depth look at the complex diagnostic challenges associated with early AD and mild cognitive impairment, and provided practical guidance on effectively and appropriately incorporating these strategies into patient care. You can now watch this on-demand version of the event! Upon completion of this activity, participants should be better able to: Employ molecular imaging tools to optimize the timely and accurate neuropathological diagnosis of AD; and Apply quantitative analysis to augment the visual interpretation of PET imaging in AD

Go online to PeerView.com/NEF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Alzheimer's disease (AD) is a devastating and highly prevalent condition, affecting 10% of people over 65 years of age, and increasing in prevalence as the population ages. Given the heavy economic and social burdens of AD, major emphasis has been placed on finding disease-modifying therapies (DMTs) that can address the underlying pathophysiology and prevent, delay, slow, or halt the inexorable decline of AD. Now, after almost two decades without a new AD treatment, recent advances in DMTs, including the accelerated approval from the FDA of two amyloid-targeting therapies (ATTs) and a third in late-stage development, have opened the door to the possibility of reductions in disease progression and improved patient outcomes. In order for these treatments to be successful, initiation in the prodromal or early symptomatic stages of AD is critical. Fortunately, significant advances have been made in the development and validation of molecular imaging techniques that may aid in an early diagnosis. It is therefore imperative that clinicians remain aware of the evolving role of molecular imaging tools (eg, amyloid PET, FDG PET, tau PET) and PET quantification techniques in the early diagnosis of AD, and are prepared to integrate these diagnostic tools into clinical practice. At a recent PeerView educational event, a panel of AD experts illustrated how to integrate validated and emerging neuroimaging biomarkers and quantitative measures into clinical practice to facilitate AD diagnosis. Through a case-based discussion, the faculty offered learners an in-depth look at the complex diagnostic challenges associated with early AD and mild cognitive impairment, and provided practical guidance on effectively and appropriately incorporating these strategies into patient care. You can now watch this on-demand version of the event! Upon completion of this activity, participants should be better able to: Employ molecular imaging tools to optimize the timely and accurate neuropathological diagnosis of AD; and Apply quantitative analysis to augment the visual interpretation of PET imaging in AD

Go online to PeerView.com/NEF860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Alzheimer's disease (AD) is a devastating and highly prevalent condition, affecting 10% of people over 65 years of age, and increasing in prevalence as the population ages. Given the heavy economic and social burdens of AD, major emphasis has been placed on finding disease-modifying therapies (DMTs) that can address the underlying pathophysiology and prevent, delay, slow, or halt the inexorable decline of AD. Now, after almost two decades without a new AD treatment, recent advances in DMTs, including the accelerated approval from the FDA of two amyloid-targeting therapies (ATTs) and a third in late-stage development, have opened the door to the possibility of reductions in disease progression and improved patient outcomes. In order for these treatments to be successful, initiation in the prodromal or early symptomatic stages of AD is critical. Fortunately, significant advances have been made in the development and validation of molecular imaging techniques that may aid in an early diagnosis. It is therefore imperative that clinicians remain aware of the evolving role of molecular imaging tools (eg, amyloid PET, FDG PET, tau PET) and PET quantification techniques in the early diagnosis of AD, and are prepared to integrate these diagnostic tools into clinical practice. At a recent PeerView educational event, a panel of AD experts illustrated how to integrate validated and emerging neuroimaging biomarkers and quantitative measures into clinical practice to facilitate AD diagnosis. Through a case-based discussion, the faculty offered learners an in-depth look at the complex diagnostic challenges associated with early AD and mild cognitive impairment, and provided practical guidance on effectively and appropriately incorporating these strategies into patient care. You can now watch this on-demand version of the event! Upon completion of this activity, participants should be better able to: Employ molecular imaging tools to optimize the timely and accurate neuropathological diagnosis of AD; and Apply quantitative analysis to augment the visual interpretation of PET imaging in AD

Today we have a special guest, Dr. Joel Topf, board-certified nephrologist and medical educator extraordinaire. Our listeners will likely recognize Dr. Topf from his prolific tweeting @Kidney_boy, as well as his numerous appearances on the Curbsiders podcast. He is a co-founder of the NephJC on Twitter, and host and founder of the NephJC podcast Freely Filtered. He is also host of the podcast Channel Your Enthusiasm, a deep dive monthly recap of the nephrology textbook Clinical Physiology of Acid Base and Electrolyte Disorders by Dr. Burton Rose (who, incidentally, is the creator of the original UpToDate). Dr. Topf wrote his own book on fluids, electrolytes and acid-base homeostasis.  He's the co-editor for the fourth edition of Nephrology Secrets and the first edition of The Handbook of Critical Care Nephrology. Dr. Topf joined us to talk about a new paper he co-authored on osmotic demyelination syndrome and hyponatremia. I'm also joined by Dr. Mita Hoppenfeld, hospitalist at the University of Utah, to talk about a new DOAC vs warfarin trial in On-X aortic valves, whether it's better to avoid hypertension or hypotension around time of surgery, and the diagnostic accuracy of CT abdomen scans without contrast. Check it out! Osmotic Demyelination and HyponatremiaApixaban vs Warfarin for On-X Aortic ValvePerioperative Blood Pressure Strategies Diagnostic Accuracy of CT Abdomen Without ContrastMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R

(2:33) - Using Machine Learning to Detect Rare DiseasesThis episode was brought to you by Mouser, our favorite place to get electronics parts for any project, whether it be a hobby at home or a prototype for work. Click HERE to learn about how a) AI is being leveraged in healthcare and b) the tools available from vendors to empower development in this area.

Nathan Carlson is a physical therapist, coach, and business owner based out of Kansas City. He specializes in the management of bone stress injuries, managing the high school and collegiate runner, and implementing resistance training with endurance athletes. Nathan teaches nationally and internationally on these topics. Nathan has two digital resources - A Guidebook to Running After a Stress Fracture and A Guidebook to Navigating High School Running. In this episode, we have an in-depth conversation on bone stress injuries. Our conversation was packed with so much valuable information that we broke it down into two episodes. In part one, we discuss bone physiology, factors that contribute to bone stress injuries, clinical perils, and radiographic tools for diagnosis. Bone stress injuries are one of the most complex and frustrating injuries for runners. After our discussion with Nathan, we hope that you will have a better understanding of the training, nutrition, and metabolic factors that need to be considered with diagnosing and treating these injuries. What we talked about: 3:10- Introduction to Nathan 6:40- Weight lifting for high school athletes 8:25- Defining a bone stress injury 11:00- Differences between a stress reaction and stress fracture and what causes them 22:05- Obtaining a more in-depth background of an athlete to learn more about the injury 25:45- Diagnosis and prognosis of bone stress injuries 38:05- Testing and imaging for bone stress injuries Show notes: Nathan's website Nathan on Instagram References: Bergman AG, Fredericson M, Ho C, Matheson GO. Asymptomatic tibial stress reactions: MRI detection and clinical follow-up in distance runners. AJR Am J Roentgenol. 2004 Sep;183(3):635-8. Hoenig T, Ackerman KE, Beck BR, Bouxsein ML, Burr DB, Hollander K, Popp KL, Rolvien T, Tenforde AS, Warden SJ. Bone stress injuries. Nat Rev Dis Primers. 2022 Apr 28;8(1):26. Kaeding CC, Miller T. The comprehensive description of stress fractures: a new classification system. J Bone Joint Surg Am. 2013 Jul 3;95(13):1214-20. Wright AA, Hegedus EJ, Lenchik L, Kuhn KJ, Santiago L, Smoliga JM. Diagnostic Accuracy of Various Imaging Modalities for Suspected Lower Extremity Stress Fractures: A Systematic Review With Evidence-Based Recommendations for Clinical Practice. Am J Sports Med. 2016 Jan;44(1):255-63. RED-S CAT - https://bjsm.bmj.com/content/bjsports/49/7/421.full.pdf

Go online to PeerView.com/FJH860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this animated educational activity, an expert in chronic inflammatory demyelinating polyneuropathy (CIDP) discusses the diagnosis, assessment, treatment, and monitoring of the disease. A patient also shares her experiences living with and treating her CIDP. Upon completion of this activity, participants should be better able to: Apply guideline-directed criteria to diagnose chronic inflammatory demyelinating polyneuropathy (CIDP), including correct interpretation of electrodiagnostic findings; Incorporate evidence surrounding efficacy, safety, and tolerability of recommended pharmacotherapies (eg, corticosteroids, IVIg, SCIg, and plasma exchange) and shared decision-making into CIDP treatment planning; and Employ validated assessment tools to monitor treatment response and guide clinical decision-making.

Drs. Thomas Hemmerling and Ahmed Alkhatip discuss the article “The Diagnostic Accuracy of Noninvasive Methods to Measure the Intracranial Pressure: A Systematic Review and Meta-Analysis” published in the March 2021 issue of Anesthesia & Analgesia.

Today we talk to one of our mentors, Valerie Carter, about her experience as a neuro PT who had the unique opportunity to study the effects of exercise on people with Parkinson's by helping her mom live very well for 30 years with PD. Valerie became really interested in utilizing the most sensitive outcome measures which led her down the road of studying backwards walking. Valerie shares why you should use the 3 Meter Backward Walking Test (3MBWT), exactly how to implement it, what the cutoff scores for falls are for the elderly and for people with PD, and more! Article in 2020 w/ Becky Farley: Diagnostic Accuracy of the 3-Meter Backward Walk Test in Persons with Parkinson Disease https://www.researchgate.net/publication/343173711_Diagnostic_Accuracy_of_the_3-Meter_Backward_Walk_Test_in_Persons_With_Parkinson_Disease  

When should you suspect clozapine-induced myocarditis? Myocarditis has nonspecific manifestations. In this episode, Dr. Phelps explains the clinical presentation and the steps to take if you suspect myocarditis. Faculty: Jim Phelps, M.D. Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D. Learn more about Premium Membership here Earn 0.5 CMEs: Quick Take Vol. 32 Clozapine-Induced Myocarditis: Electronic Health Register Analysis of Incidence, Timing, Clinical Markers, and Diagnostic Accuracy