Podcasts about inhaled

Flow of the respiratory current into an organism

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Best podcasts about inhaled

Latest podcast episodes about inhaled

iCritical Care: All Audio
SCCMPod-572: Propofol in the ICU: Balancing Sedation and Stability

iCritical Care: All Audio

Play Episode Listen Later Jun 30, 2026 39:50


Propofol remains a cornerstone sedative for mechanically ventilated critically ill patients and is supported by PADIS guidelines and favored for its rapid onset, titratability, and limited side effects. However, its use in hemodynamically unstable patients remains a persistent clinical dilemma. In this episode of the Society of Critical Care Medicine (SCCM) Podcast, host Kyle Enfield, MD, is joined by Scott Benken, PharmD, MHPE, BCCCP, and Nathan Smischney, MD, MS, to explore the risks, benefits, and evolving evidence surrounding propofol use in this high-risk population.     The discussion examines the physiologic basis of propofol-associated hypotension and how that can manifest in different patients, such as those with sepsis and septic shock. Patient selection and real-time assessment of hemodynamic trends are essential. Additional considerations include the recognition of and monitoring for propofol infusion syndrome, a rare but life-threatening complication.     The episode also explores alternative drugs such as dexmedetomidine and ketamine, highlighting the benefits and risks of each. Emerging strategies are discussed, including a ketamine-propofol combination called ketafol and its utility in balancing sedation and hemodynamic stability.  Listeners will gain expert insights into propofol use in the ICU and a deeper understanding of patient-centered approaches to sedation.    Resources referenced in this episode:   Lewis K, Balas MC, Stollings JL, et al. A focused update to the clinical practice guidelines for the prevention and management of pain, anxiety, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU. Crit Care Med. 2025;53(3):e711-e727.  Russotto V, Myatra SN, Laffey JG, et al. Intubation practices and adverse peri-intubation events in critically ill patients from 29 countries. JAMA. 2021;325(12):1164-1172.  Boncyk C, Devlin JW, Faisal H, et al. INhaled Sedation versus Propofol in REspiratory failure in the Intensive Care Unit (INSPiRE-ICU1): protocol for a randomised, controlled trial. BMJ Open. 2024;14(10):e086946.  O'Gara B, Serra AL, Englert JA, et al. Inhaled sedation versus propofol in respiratory failure in the ICU (INSPiRE-ICU2): study protocol for a multicenter randomized controlled trial. Trials. 2025;26(1):114. 

Taking Control Of Your Diabetes - The Podcast!
Inhaled Insulin Just Got FDA-Approved for Kids With Type 1

Taking Control Of Your Diabetes - The Podcast!

Play Episode Listen Later Jun 29, 2026 32:26


In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by pediatric endocrinologist Dr. Anna Cymbaluk, along with Philip and his father Jim, to discuss the recent FDA approval of Afrezza inhaled insulin for children and adolescents living with type 1 diabetes. Dr. Cymbaluk served as an investigator on the INHALE-1 trial, while Philip participated in the study himself, providing a unique real-world perspective on what it is like to transition from injections to inhaled insulin, and Philip's dad, Jim provided the parent perspective as well as addressed parental concerns that might have arisen.The conversation focuses on the INHALE-1 study and the unmet challenges that continue to exist around mealtime insulin dosing in pediatric diabetes care. Dr. Cymbaluk reviews the trial design, glucose outcomes, safety data, patient satisfaction findings, and the practical realities of introducing inhaled insulin into everyday diabetes management. Philip and Jim share how Afrezza impacted school, sports, social situations, and the day-to-day burden of diabetes, particularly around pre-bolusing, corrections, and avoiding multiple injections throughout the day.Dr. Edelman and Dr. Cymbaluk also explore how Afrezza is dosed, how inhaled insulin differs from injected insulin, who may be a good candidate, and where it may fit alongside pumps and automated insulin delivery (AID) systems. For families looking for more flexibility, fewer mealtime barriers, and another option in the diabetes toolbox, this episode provides an honest look at the benefits, limitations, and real-world experience of inhaled insulin in children and teens.Key Topics• The FDA approval of Afrezza for children and adolescents living with type 1 diabetes• The design and results of the INHALE-1 pediatric clinical trial• Patient satisfaction and quality-of-life outcomes from the study• The challenges of pre-bolusing and mealtime insulin management in children and teens• How inhaled insulin compares to traditional mealtime injections• Dosing strategies, cartridge sizes, and insulin conversion considerations• Using Afrezza for corrections, meals, and post-meal dosing• The role of continuous glucose monitoring (CGM) when using inhaled insulin• Safety findings, lung-function monitoring, and cough management• Who may be a good candidate for Afrezza—and who may not be• Benefits for active children, athletes, and those participating in sports• Social situations, injection avoidance, and reducing the burden of diabetes management• Using Afrezza alongside insulin pumps and automated insulin delivery (AID) systems• The importance of having more treatment options to individualize diabetes careSupported by an unrestricted educational grant from MannKind CorporationSubscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram: / tcoydFacebook: / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Diabetes Dialogue: Therapeutics, Technology, & Real-World Perspectives
Teplizumab, Stelo, and Inhaled Insulin Afrezza for Pediatric Patients

Diabetes Dialogue: Therapeutics, Technology, & Real-World Perspectives

Play Episode Listen Later Jun 18, 2026 27:28


Welcome back to Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives!In this episode, cohosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss a series of major pediatric diabetes advancements announced around the American Diabetes Association (ADA) Scientific Sessions 2026, highlighting how recent regulatory decisions are expanding treatment options and improving access to diabetes technologies.The conversation opens with the expanded FDA indication for teplizumab in children and adolescents with newly diagnosed stage 3 type 1 diabetes. Bellini reviews findings from the PROTECT trial, which evaluated teplizumab in patients ages 8 to 17 years within six weeks of diagnosis. She explains that treatment with two 12-day infusion courses resulted in significant preservation of endogenous insulin production, with 95% of participants maintaining peak C-peptide levels above the study threshold at week 78. The hosts discuss the importance of preserving residual beta-cell function, emphasizing its potential role in improving glycemic stability, reducing hypoglycemia risk, and supporting better long-term outcomes for individuals who will live with type 1 diabetes for decades.Isaacs and Bellini explore how this new indication may change the approach to type 1 diabetes screening, particularly among first-degree relatives and individuals at higher risk for autoimmune disease. They note that identifying people in stage 2 type 1 diabetes remains challenging because patients are typically asymptomatic, but the availability of treatment at stage 3 provides clinicians with a new opportunity to intervene soon after diagnosis.The hosts discuss how having an approved therapy may encourage more families to pursue screening and identify additional individuals with early-stage disease. They also address practical considerations, including the importance of starting treatment within the appropriate window, coordinating the two infusion courses, supporting families through treatment logistics, and ensuring access through insurance coverage.The discussion then shifts to the FDA clearance of Dexcom Stelo, the first over-the-counter glucose biosensor cleared for pediatric use in children ages 2 years and older who do not use insulin. Isaacs highlights how this technology could improve access to glucose monitoring for children with prediabetes, type 2 diabetes, or those seeking greater insight into how food, activity, and lifestyle factors influence glucose patterns.The hosts emphasize that expanded access to glucose monitoring could play an important role in helping families make informed decisions about diabetes management. However, they clarify that individuals using insulin require prescription continuous glucose monitoring systems with additional safety features, including hypoglycemia alerts and predictive low glucose notifications.Finally, Isaacs and Bellini discuss the pediatric approval of inhaled insulin as another significant milestone in diabetes care. They review its potential as an alternative to mealtime injections and highlight the opportunity to provide more flexibility for children and families managing type 1 diabetes. The conversation also addresses implementation considerations, including baseline lung function testing, provider familiarity, and adapting clinical workflows to incorporate new treatment approaches.The episode concludes by reflecting on the rapid progress occurring in pediatric diabetes care. With advances in immune-modulating therapies, glucose monitoring technology, and insulin delivery options, the hosts highlight a new era of personalized diabetes management focused on preserving insulin function, improving access, and optimizing outcomes for young people living with diabetes.Editors' Note: Isaacs reports disclosures with Dexcom, Abbott, Lilly, Novo Nordisk, Medtronic, Insulet, and others. Bellini reports disclosures with Abbott Diabetes Care, MannKind, Povention Bio, and others.References1: Sanofi. Press Release: Sanofi's Tzield approved in the US as the first disease-modifying therapy for patients recently diagnosed with stage 3 type 1 diabetes. June 12, 2026. Accessed June 18, 2026. https://www.sanofi.com/en/media-room/press-releases/2026/2026-06-12-22-09-58-33113492: US Food and Drug Administration. FDA Clears First Over-the-Counter Continuous Glucose Monitor for Children. June 12, 2026. Accessed June 18, 2026. https://www.fda.gov/news-events/press-announcements/fda-clears-first-over-counter-continuous-glucose-monitor-children3: Livingston R. FDA Approves Inhaled Insulin Afrezza for Pediatric Patients With Diabetes. HCPLive. May 29, 2026. Accessed June 18, 2026. https://www.hcplive.com/view/fda-approves-inhaled-insulin-afrezza-pediatric-patients-diabetes

Taking Control Of Your Diabetes - The Podcast!
Inhaled Insulin for Kids: Inside the INHALE-1 Trial

Taking Control Of Your Diabetes - The Podcast!

Play Episode Listen Later Jun 15, 2026 45:05


In this episode of the TCOYD Podcast, Dr. Edelman and Dr. Pettus are joined by pediatric endocrinologist Dr. Jamie Wood, medical director of pediatric diabetes at Rainbow Babies & Children's Hospital and an investigator on the INHALE-1 trial, to talk through inhaled insulin in kids and where it fits in real-world pediatric care.The conversation focuses on the recent approval of Afrezza for children as young as six, and what the INHALE-1 trial actually showed. Dr. Wood walks through the study design, A1C results, lung-function and safety data, and the practical aspects of dosing inhaled insulin in a pediatric population. Rather than positioning it as a replacement for injections or pumps, the discussion centers on finding the right fit for each child's needs, from the newly diagnosed kid with a needle phobia to the teen trying to dose discreetly during a 20-minute school lunch.Dr. E, Dr. P, and Dr. Wood also discuss the everyday realities that shape how this option is used, including the set-dose cartridge sizes, a titration approach refined in clinic, and how families are mixing and matching tools alongside automated insulin delivery. The takeaway is encouraging: there are more options than ever for managing mealtime insulin in kids, and this one may help fill some of the gaps left by injections and pumps.Key Topics • The recent approval of inhaled insulin for children as young as six • How the INHALE-1 pediatric trial was designed • A1C results and what the primary endpoint analysis showed • Continuous glucose monitor (CGM) metrics across the two groups • Lung-function (FEV1) monitoring and pediatric safety • Weight and body mass index (BMI) findings • Why mealtime dosing is a leading unmet need in pediatric type 1 diabetes (T1D) • The set-dose cartridge approach and how it reframes meal sizes • A real-world titration method for inhaled insulin • Managing cough and other practical considerations • Needle phobia and the kids who struggle most with injections • Using inhaled insulin alongside automated insulin delivery (AID) systems • What's coming next, including a smaller cartridge dose and a new-onset trial Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram: / tcoydFacebook: / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

The Lancet Respiratory Medicine
Andrew Bush, Heather Zar, Fernando de Benedictis on how inhaled corticosteroids have changed the treatment of asthma

The Lancet Respiratory Medicine

Play Episode Listen Later Jun 15, 2026 13:25


Andrew Bush, Heather Zar, Fernando de Benedictis talk about their recent personal view piece where they summarise and discuss the 50-year journey and evolution of inhaled corticosteroids (ICS) in asthma treatment. Click here to read the full articles: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(26)00082-2/abstract

Shooting the Shiznit
BSIDE1075 CLIP “..just never inhaled...”Subscribe !

Shooting the Shiznit

Play Episode Listen Later Jun 6, 2026 11:06


BSIDE is all the things that you do not get to hear during the regular recording of the episodes. It might be before the mic, after the mics or right in the middle ! We also post the UNCUT video version every week on Patreon ! We have close to 1000 episodes and many tiers. How do you get to listen to the UNCUT version ? Subscribe for $5 at www.patreon.com/shootintheshiznit ! We also stream all of the UNCUT episodes as they are happening and they go into the Patreon archives ! We have had close to 1000 posts in over five years and it grows every week. Get over the www.patreon.com/shootintheshiznit and subscribe ! https://soundcloud.com/shootintheshiznit/hit-me-with-your-first-shot-2/s-yyukXYmigSM?si=86b42ab102f14709ba7679590b05e70a&utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing

Diabetes Connections with Stacey Simms Type 1 Diabetes
BONUS Episode: Afrezza Approved for Kids: A Deep Dive Into Inhaled Insulin with INHALE-1 Lead Investigator Dr. Jamie Wood

Diabetes Connections with Stacey Simms Type 1 Diabetes

Play Episode Listen Later Jun 4, 2026 36:33


On this bonus episode of Diabetes Connections.. a deep dive into inhaled insulin for kids. Last week the FDA approved Afrezza for kids six and older – it's been approved for adults for more than a decade – and boy did you have questions. We're talking to Dr. Jamie Wood, pediatric endocrinologist and  principal investigator of the INHALE-1 trial that helped lead to this approval. We're talking about what that studied showed, what the approval means, how to use Afrezza, and a bunch of your questions. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Our prevous episodes on Afrezza: https://diabetes-connections.com/?s=afrezza Our previous episode with Dr. Jamie Wood: https://diabetes-connections.com/top-ten-calls-your-endo-gets-in-the-middle-of-the-night/ Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com   

Diabetes Connections with Stacey Simms Type 1 Diabetes
In the News.. Inhaled Insulin Approved for Kids, CGM + Ketone Monitor, Food Coloring & Diabetes Study, Device Recalls and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

Play Episode Listen Later Jun 2, 2026 14:37


It's in the News! The top diabetes stories and headlines happening now. Top stories this week include: Afrezza inhaled Insulin is Approved for Kids, CGM + Ketone Monitor gets European approval, Food Coloring & Diabetes Study, Device Recalls include Omnipod and Dexcom, Beta Bionics shares more about their patch pump, ADA conference info and more! This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Episode transcripts: Welcome! I'm your host Stacey Simms and this is an In The News episode.. where we bring you the top diabetes stories and headlines happening now. A reminder that you can find the sources and links and a transcript and more info for every story mentioned here in the show notes. ADA starts this week – safe travels to those of you heading to New Orleans. We'll be covering remotely so please follow on social – make sure to Like the FB page or join the group. We've got a wrap up episode planned for this podcast as well as some indepth interviews with the newsmakers from the conference. I will see some of you next week in Chicago. We have a couple of seats left for our Club 1921 dinner on June 10th in Northbrook – this is a FREE dinner for HCPs and patient leaders – all about screening for T1D. More info on the website under the events tab. Okay.. our top story this week: XX Afrezza inhaled insulin is now approved for kids and teens. The FDA okayed MannKind's afrezza for children 6 and older with type 1 and type 2 diabetes. MannKind says its proprietary Technosphere drug delivery platform enables the rapid absorption of insulin into systemic circulation. This follows FDA approval earlier this year for an update that revises recommendations for the starting mealtime dosage when patients switch from subcutaneous mealtime insulin regimens. MannKind also completed enrollment in February for a study evaluating the initiation of Afrezza therapy shortly after type 1 diabetes diagnosis in pediatric patients.   The company said it made Afrezza available for eligible patients for $35 or less per month. Desmond Schatz, professor of pediatrics at the University of Florida College of Medicine, said: "Mealtime insulin can be especially challenging for children because eating and snacking patterns, activity levels, and daily settings like school and sports often vary. With its rapid onset and dosing at the start of a meal, Afrezza may help clinicians better match insulin therapy to how children and families live day to day, while offering a needle-free mealtime option." Lots more to come on this – we're working on a bonus episode with one of the pediatric endos who worked on the clinical trials that led to this approval – hopefully have that out later this week. https://www.massdevice.com/mannkind-fda-approval-inhaled-insulin-children/ XX FDA has agreed to consider a new drug for the treatment of adults with type 1 and chronic kidney disease. Finerenone (fy-near-uh-known) is currently approved in the US for adults with CKD associated with type 2 diabetes and for adults with heart failure with left ventricular ejection fraction of 40% or greater. Chronic kidney disease (CKD) is present in over one-third of adults with diabetes, and because it's such a serious condition, interventions are needed to reduce its incidence and help people live a long and prosperous life. https://www.docwirenews.com/post/fda-grants-priority-review-to-finerenone-snda-for-type-1-diabetes-associated-ckd XX Abbot gets European approval for the world's first dual glucose‑ketone sensing technology for people with diabetes. They're calling this Libre Duo and Libre Duo 10 Day, and it's designed to continuously measure glucose and ketone levels every minute. Abbott plans to begin launching Libre Duo systems in select European countries later this year. Libre Duo delivers up to 15 days of wear and will be offered to adults ages 18 and older. Libre Duo 10 Day offers up to 10 days of wear and is intended for people ages 2 and older. Abbott is also working with leading pump companies to allow automated insulin delivery (AID) systems to connect with the sensors. https://abbott.mediaroom.com/2026-05-27-Abbott-secures-CE-Mark-for-worlds-first-dual-glucose-ketone-sensing-technology-for-people-with-diabetes   XX Huge recall for Omnipod. Insulin says a manufacturing issue through ongoing product monitoring that could result in insulin under-delivery  with specific lots of its Omnipod 5, Dash and Eros pods. Insulet said the scope of this action reaches approximately 7 million pods. This issue is separate from the March recall that affected certain Omnipod 5 lots. According to the Acton, Massachusetts-based company, some of its affected pods may have a small tear in the tubing (cannula) just above the skin. This tear lands between the pod and the point where the cannula enters the body. If this occurs, insulin may leak outside of the device instead of being fully delivered into the body as intended. This may lead to under-delivery of the therapeutic.   Individuals using an affected pod may notice wetness on the skin or pod adhesive or detect the smell of insulin. However, some cases may prove difficult to detect and go unnoticed. Of the approximately 7 million pods included in the action, approximately 60% have been consumed or are expired. The pods affected by the correction represent approximately 8.5% of the 2025 global Omnipod pod prodcution. Insulet says it has sufficient supply to replace affected pods. It expects no disruption to product availability. The company said it has notified the FDA and all other relevant regulatory authorities of its action.   The full list of affected pod lots can be found here. https://www.massdevice.com/insulet-another-omnipod-5-recall-dash-eros/ XX Dexcom is warning that certain scrapped glucose sensors have been stolen and resold. Dexcom said it has not received any reports of severe adverse events associated with the stolen product. One lot of scrapped devices carries a risk of infection for sensors that are not properly sterilized, and another lot had an elevated internal testing failure rate, meaning users would have an increased risk of having no sensor readings available. Dexcom said the affected sensors were stolen during the destruction process and then sold by third parties. The company routinely scraps sensors that do not meet its standards. The sensors are sent to a third-party vendor for destruction and recycling.   Dexcom said it traced sales of the stolen devices to Pharmsource, which is not an authorized Dexcom distributor but supplies some independent pharmacies and U.S. durable medical equipment distributors. Because of this, pharmacies that purchase products from Pharmsource should review their inventory, Dexcom said.   People with sensors from the affected lots should not use those sensors and can call customer support to request replacements. Dexcom has set up a website to help users check if their devices are affected. https://www.medtechdive.com/news/dexcom-warns-of-scrapped-glucose-sensors-being-resold/821139/ XX XX   Beta Bionics plans to debut its first insulin patch pump by the end of the second quarter of 2027, subject to Food and Drug Administration clearance. The device, called Mint, would be compatible with Beta Bionics' interoperable automated glycemic controller, a software that allows for the pump to automatically adjust insulin delivery based on readings from a glucose sensor. Beta Bionics first unveiled the prototype for Mint last year at the American Diabetes Association's Scientific Sessions. The device is expected to have a similar size and wear time, at three days, to Insulet's patch pumps on the market. It would have a 200-unit insulin reservoir.   Mint differs by containing a mix of reusable and disposable components. Beta Bionics plans to make the device exclusively available in the pharmacy channel, building on its existing agreements for its current iLet insulin pump. Beta Bionics is one of several diabetes tech companies developing patch pumps to compete with market leader Insulet. Tandem Diabetes Care and Medtronic spinoff MiniMed have also announced planned patch pumps. Tandem said it plans to file a 510(k) submission this quarter for a tubeless version of its small, durable pump, and Medtronic plans to submit its patch pump to the FDA this fall.   https://www.medtechdive.com/news/beta-bionics-to-launch-its-first-insulin-patch-pump-to-compete-with-insulet/821091/ XX CVS puts Zepbound back on it's coverage list – with it's Caremark PBM. They also added Foundayo, Lilly's obesity pill. CVS had dropped Lilly's Zepound last summer but kept competitor Wegovy. It'll be back at Caremark October first. All three of the nation's largest pharmacy ⁠benefit managers ​now cover Lilly's full obesity medicine portfolio. https://www.reuters.com/legal/litigation/cvs-brings-back-coverage-lillys-obesity-drug-zepbound-2026-05-28/   More to come, including a new benefit from metformin for women, something new from Tidepool, big news for T1D in Austalia and more.. XX A new study suggests that higher long-term exposure to food colouring additives — including both synthetic and natural colourings commonly found in processed foods and beverages — may be associated with an increased risk of developing type 2 diabetes. Researchers analyzed data from more than 108,000 adults in the French NutriNet-Santé cohort between 2009 and 2023, following participants for a median of just over eight years. During that time, 1,131 participants developed type 2 diabetes. The study found that people with the highest intake of total food colouring additives had a 38% higher risk of developing type 2 diabetes compared with non- or low-consumers.   Several specific additives were linked to increased risk, including caramel colouring additives such as total caramel (E150 family), plain caramel (E150a), sulphite ammonia caramel (E150d), and beta-carotene (E160a). Additional associations were observed for curcumin (E100), anthocyanins (E163), paprika extract (E160c), lutein (E161b), and cochineal-derived colourings (E120). "Our findings revealed positive associations between widely consumed food colouring additives and type 2 diabetes incidence," the authors wrote, adding that further research is needed to better understand the mechanisms behind the findings and whether food colouring regulations should be reevaluated. https://www.medscape.com/viewarticle/use-common-food-colours-tied-high-type-2-diabetes-risk-2026a1000hes XX Big news for Australia – their Therapeutic Goods Administration (TGA) approves Tzield. Tzield is now approved in Australia to delay the onset of stage 3 (or clinical) T1D in people aged eight years and older with stage 2 T1D – the early, pre-symptomatic stage of the condition, where changes in blood glucose levels have begun but insulin therapy is not yet required. Breakthrough T1D Australia Chief Executive Officer, Sydney Yovic, said the approval represented a transformational moment for Australians affected by T1D. https://newshub.medianet.com.au/2026/05/landmark-approval-of-tzield-in-australia-ushers-in-a-new-era-of-delay-for-type-1-diabetes/155036/ XX https://www.theatlantic.com/health/2026/05/diabetes-pregnancy/687324/ XX A common diabetes drug may hold great potential to help with aging, even if scientists aren't exactly sure why. According to a study, the drug metformin doesn't just help patients to effectively manage their type 2 diabetes. it may also give older women a better chance of living to 90. Scientists in the US and Germany used data from a long-term US study of postmenopausal women.   Records for a total of 438 people were selected – half of whom took metformin to treat diabetes, and half of whom took a different diabetes drug, sulfonylurea.   While there are some caveats and asterisks to the study, those in the metformin group were calculated to have a 30 percent lower risk of dying before the age of 90 than those in the sulfonylurea group. The study used age 90 as the marker for 'exceptional' longevity. However, scientists aren't yet sure that the drug extends lifespan, especially in humans – which is part of the reason for this study. RCTs could follow further down the line to dig deeper into these results, the researchers suggest. In the meantime, as the global population continues to skew older, studies continue to find ways to keep us healthier for longer and reduce damage to the body as we age. https://www.sciencealert.com/a-common-diabetes-drug-is-linked-with-exceptional-longevity-in-women XX The American Diabetes Association® (ADA) will host the 2026 Scientific Sessions from June 5-8 in New Orleans. The ADA's Scientific Sessions is the world's largest diabetes meeting, convening an expected audience of over 12,000 leading physicians, scientists, researchers, and healthcare professionals from around the globe. The premier diabetes meeting, which is also offered virtually, will feature the latest scientific findings in diabetes and obesity, where leading experts and peers will share findings in research for prevention, care, and cures at the Ernest N. Morial Convention Center. Key themes will include: Advancing obesity and metabolic health: Prevention, early detection, and disease modification: Improving cardiometabolic outcomes: Transforming care through innovation and access: New research will highlight how technology, artificial intelligence, and implementation strategies are reshaping diabetes care—reducing treatment burden, expanding access, and enabling more person-centered care. Advancing beta cell replacement and cure strategies: Fostering innovation: On Saturday, June 6, from 4:30-6:00 p.m., the Innovation Challenge, which debuted in 2023, invites emerging companies to pitch novel ideas to improve the lives of people living with diabetes. A panel of judges, with input from a live audience, determines which contestants will earn a private audience with potential funders. XX Tidepool, the nonprofit leader advancing innovation in diabetes technology, announced that Tidepool+ Direct Connect is now available through the Epic Showroom. Built on SMART on FHIR, Direct Connect brings interactive diabetes device data directly into Epic workflows, helping clinicians use patient data during routine care. "Tidepool has always focused on making diabetes data more accessible and actionable," said Brandon Arbiter, CEO. "We're excited to empower clinicians using Epic with insightful, intuitive patient data that fits directly into their encounter workflow so they can use it to improve care in the moment it matters."   Tidepool+ Direct Connect supports scalable deployment across Epic-enabled health systems. This architecture enables faster, more intuitive rollouts, enhancing Tidepool's existing EHR integration capabilities.   Direct Connect is part of Tidepool's ongoing work to improve how clinicians can use timely and relevant diabetes device data during patient visits to help drive better health outcomes.   The feature is now available in the Connection Hub of the Epic Showroom.   https://www.businesswire.com/news/home/20260527780274/en/Tidepool-Launches-in-Epic-Showroom-to-Bring-Diabetes-Device-Data-into-the-Point-of-Care XX

Diabetes Dialogue: Therapeutics, Technology, & Real-World Perspectives
FDA Approves Afrezza Inhaled Insulin for Pediatric Patients

Diabetes Dialogue: Therapeutics, Technology, & Real-World Perspectives

Play Episode Listen Later May 29, 2026 11:30


Welcome back to Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives!In this episode, cohosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss the recent FDA approval of MannKind's inhaled insulin Afrezza for pediatric patients aged 6 years and older with both type 1 and type 2 diabetes, describing the decision as a major milestone in diabetes therapeutics and the first expansion of the therapy beyond adults. The episode centers on the clinical implications of the approval, the pharmacologic advantages of inhaled insulin, and the practical considerations surrounding implementation in pediatric care settings.The hosts review findings from the INHALE-1 trial, which enrolled 230 pediatric participants aged 4 to 17 years and compared inhaled insulin used alongside basal insulin with standard multiple daily injection (MDI) therapy over 56 weeks. Bellini emphasizes that the study achieved its primary objective of demonstrating glycemic outcomes comparable to traditional insulin regimens, noting that insulin studies are generally designed to establish equivalence rather than superiority. Beyond similar glycemic control, the hosts highlight several clinically meaningful secondary observations, including stable BMI among participants receiving inhaled insulin compared with weight gain in the MDI cohort, increased treatment satisfaction reported by both adolescents and parents of younger children, comparable hypoglycemia rates, and the absence of new safety concerns. Bellini also notes that no decline in lung function was observed among participants using inhaled insulin, despite historical concerns surrounding pulmonary safety with inhaled therapies.A major focus of the discussion is the physiologic pharmacokinetic profile of Afrezza, which Isaacs characterizes as the most physiologic insulin currently available. She explains that inhaled insulin demonstrates measurable activity within approximately 12 minutes, peaks within 35 to 45 minutes, and clears the bloodstream in roughly 90 minutes. The hosts contrast this with subcutaneous rapid-acting insulin analogs, including ultra-rapid formulations, which retain a prolonged “tail” of insulin activity that can increase hypoglycemia risk. Isaacs and Bellini suggest that the shorter duration of inhaled insulin may reduce the cycle of overtreating hypoglycemia and subsequent rebound hyperglycemia, thereby potentially contributing to the absence of weight gain observed in the trial. Bellini further emphasizes that the rapid onset and offset of inhaled insulin restore some of the flexibility and spontaneity often lost in intensive insulin therapy, particularly around meal dosing and correction strategies.The conversation also situates inhaled insulin within the broader framework of individualized diabetes management and the ADA Standards of Care. Isaacs stresses that the approval should not be viewed as competing with automated insulin delivery (AID) systems, but rather as expanding patient choice. The hosts discuss how inhaled insulin may be especially valuable for individuals who do not wish to wear insulin pumps, desire periodic breaks from technology, or want to reduce the burden of injections. Isaacs additionally highlights the growing prevalence of pediatric type 2 diabetes and notes that, despite advances in incretin-based therapies, many youth still require insulin therapy. In that context, the possibility of pairing inhaled mealtime insulin with emerging once-weekly basal insulin formulations and GLP-1 receptor agonists is presented as a potentially transformative strategy for minimizing injection burden.Bellini and Isaacs also address practical implementation challenges within school settings. Because inhaled insulin acts rapidly, Bellini notes that administration timing may need to shift from the nurse's office to the cafeteria environment to avoid hypoglycemia if meals are delayed. At the same time, both hosts recognize that the flexibility of postprandial dosing could offer advantages for children with inconsistent eating patterns or concerns about privacy surrounding insulin administration. They further discuss the utility of inhaled insulin for rapid glucose corrections, noting that additional doses can be administered far sooner than with traditional injected rapid-acting insulin.The episode concludes with discussion of anticipated affordability initiatives from MannKind Corporation, including bridge programs designed to improve early access and reduce financial barriers to therapy. Isaacs and Bellini commend the company's efforts to secure pediatric approval and express optimism that broader availability of inhaled insulin will expand individualized treatment options, improve patient satisfaction, and enhance quality of life for children and adolescents living with diabetes.Editors' Note: Isaacs reports disclosures with Dexcom, Abbott, Lilly, Novo Nordisk, Medtronic, Insulet, and others. Bellini reports disclosures with Abbott Diabetes Care, MannKind, Povention Bio, and others.References1: HOLDER

Primary Care Update
Episode 205: inhaled steroid dose, titrating GLP-1s, zoster vaccine and dementia, and trusting AI

Primary Care Update

Play Episode Listen Later Apr 29, 2026 36:32


This week, primary care doctors Kate, Gary, Mark and Henry discuss high vs low dose inhaled steroids for high risk patients with asthma, click based semaglutide titration to reduce GI problems, zoster vaccine and dementia risk, and whether we are trusting AI too much.  

Primary Care Update
Episode 203: melatonin for dementia, new PE guidelies, inhaled steroids for asthma

Primary Care Update

Play Episode Listen Later Apr 5, 2026 28:54


This week, primary care physicians Henry Barry, Gary Ferenchick and Mark Ebell discuss several new studies: melatonin for older adults with cognitive impairment, new pulmonary embolism guidelines, and inhaled corticosteroid dosing for children and adults with asthma. Kate has the week off.

JDD Podcast
JDD Podcast: Inhaled, Applied, Prescribed: Steroids Through the Allergy Lens

JDD Podcast

Play Episode Listen Later Mar 6, 2026 34:20


The post JDD Podcast: Inhaled, Applied, Prescribed: Steroids Through the Allergy Lens appeared first on JDDonline - Journal of Drugs in Dermatology.

JDD Podcast
Inhaled, Applied, Prescribed: Steroids Through the Allergy Lens

JDD Podcast

Play Episode Listen Later Mar 6, 2026 34:20


The post Inhaled, Applied, Prescribed: Steroids Through the Allergy Lens appeared first on JDDonline - Journal of Drugs in Dermatology.

Out of the Blue: An AJRCCM Podcast
Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation and Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids

Out of the Blue: An AJRCCM Podcast

Play Episode Listen Later Jan 29, 2026 25:59


Dr. John Fleetham chats with Dr. Barbro N Melgert and Dr. Chris Carlsten about their articles, "Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation" and "Inhaled Microplastics and Airway Development: Concerning Evidence from Organoids."

Reefer MEDness
E165 – Inhaled cannabis therapy benefits diabetic care mapping - Dr. Dror Robinson

Reefer MEDness

Play Episode Listen Later Jan 28, 2026 44:40


Dr. Dror Robinson's five-year longitudinal Israeli study goal was to evaluate inhaled cannabis use for diabetic neuropathy. He found it works and he now believes all diabetics should be inhaling cannabis flower. The study can be faulted for the lack of diversity with the 52 individuals sampled, however the study presents a 97% sample retention, and the evidence suggests every participant benefitted from the in-haled cannabis therapy. In this episode, Kirk and Trevor discuss the real-world application of cannabis medicine found to reduce pain, positively modulates the A1C, and decreases the pharmaceutical costs for people with diabetes. This is a must listen for those who are affected by diabetes.Dr. Robinson - LinkedInTranscripts, papers and so much more at: reefermed.ca

The 2TYPEONES Podcast
#320: From Pig Insulin to Inhaled Insulin - Adriana's 35-Year Journey with T1D

The 2TYPEONES Podcast

Play Episode Listen Later Dec 2, 2025 63:28


Hey Diabuddy thank you for listening to show, send me some positive vibes with your favorite part of this episode.In this powerful episode, I sit down with Adriana Wright, who was diagnosed with Type 1 diabetes at just four years old and has now lived with T1D for nearly 35 years. Her story begins in the early 1990s — the “dark ages” of diabetes care — when blood sugar testing required giant blood drops, no CGMs existed, and kids with T1D often felt isolated, limited, or misunderstood.Adriana shares what it was like to grow up with diabetes before modern tools existed, how her family adapted overnight, and how resilience became the thread that carried her through childhood, adolescence, motherhood, and adulthood.

Taking Control Of Your Diabetes - The Podcast!
Inhaled Insulin (Afrezza): Dosing, Timing & The Power of Inhaled Insulin

Taking Control Of Your Diabetes - The Podcast!

Play Episode Listen Later Nov 24, 2025 29:57


Get a practical breakdown of Afrezza, the ultra-rapid inhaled insulin, with this comprehensive guide to efficacy, timing, and real-world application. Join Drs. Jeremy Pettus and Steve Edelman—endocrinologists living with Type 1 diabetes—as they reveal why this unique tool is often misunderstood and how to use it effectively to flatten post-meal spikes.In this episode, we move beyond the basics to correct the biggest mistake users make regarding Afrezza dosage. If you've tried this therapy before and felt it "didn't work," the issue often lies in the conversion ratio. We review data from Afrezza MannKind studies (such as INHALE-3) to explain the shift from the old 1:1 ratio to the more effective 1:3 ratio. We also cover why this "rapid-on, rapid-off" insulin is the ultimate solution for exercise and how to navigate insurance coverage and prior authorizations.Topics covered in this episode:The Dosing Fix: Why you often need a higher Afrezza dosage compared to subcutaneous insulin.Speed & Kinetics: How inhaled insulin mimics the body's natural beta cells to clear glucose fast.Lifestyle Benefits: Managing "sticky highs," exercise without crashing, and dietary freedom.Safety & Screening: Spirometry requirements and who should (and shouldn't) use Afrezza.Pediatric Updates: The latest on clinical trials and potential approval for children.Whether you are managing Type 1 or Type 2 diabetes, this episode provides the practical "tips and tricks" you need to determine if Afrezza is the missing tool in your diabetes management kitTimecodes: 0:00 Intro: Inhaled Insulin History 0:59 How Fast is Afrezza? (Rapid On/Rapid Off) 2:19 Why It Prevents "Delayed Lows" 3:24 The Big Mistake: Why Dr. Pettis Quit Using It 5:20 The Correct Dosing Conversion (1:1 vs 1:3) 7:40 Timing: Do You Need to Pre-Bolus? 8:44 "Follow-On" Dosing for High Protein/Fat Meals 10:32 Cartridge Sizes & "Bucket" Dosing 12:11 Using Inhaled Insulin for Exercise 13:58 Real-World Test: Trix Cereal & Afrezza 15:00 Storage Tips: Fridge vs. Room Temp 16:20 Dealing with the Cough Side Effect 17:05 Proper Inhalation Technique 19:13 Using Afrezza with Insulin Pumps & Closed Loops 21:30 Pediatric Update: Is it Safe for Kids? 23:25 Lung Safety, Smokers & Spirometry Tests 24:25 How to Talk to Your Doctor About Afrezza 26:32 Prescriptions & Trainers 28:44 ConclusionVisit TCOYD's Website for more diabetes edutainment for people living with diabetes: tcoyd.org**Tune in for two new episodes each month! Like what you hear and want to help us grow? Please rate and review this podcast so we can reach more people living with diabetes!**Follow our social media channels to empower yourself with the essential areas of diabetes knowledge led by two endocrinologists living with type 1 diabetes: Facebook  |  Instagram  |  YouTube ★ Support this podcast ★

Galactic Horrors
I Inhaled A Dead Alien's Memories. It's Resurrecting A Civilization Through Me | Sci-Fi Story

Galactic Horrors

Play Episode Listen Later Nov 11, 2025 92:24


Keeping Current CME
Beyond the Inhaled Corticosteroid Plateau: Targeted Strategies for Moderate to Severe Asthma

Keeping Current CME

Play Episode Listen Later Oct 14, 2025 27:01


How can targeted treatments address persistent airway obstruction, small airway disease, and mucus plugs? Credit available for this activity expires: 10/14/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/beyond-inhaled-corticosteroid-plateau-targeted-strategies-2025a1000r55?ecd=bdc_podcast_libsyn_mscpedu

The Diary Of A CEO by Steven Bartlett
Neil deGrasse Tyson: The Brutal Truth About Astrology! Our Breath Contains Molecules Jesus Inhaled!

The Diary Of A CEO by Steven Bartlett

Play Episode Listen Later Oct 13, 2025 126:09


Dr Neil deGrasse Tyson, world-renowned astrophysicist, breaks down the universe, space, black holes, and the Big Bang, uncovering how Elon Musk, AI, SpaceX, and NASA are defining the future of humanity.  As a science communicator, Neil is the host of StarTalk podcast, which covers science, pop culture and comedy. He is also the bestselling author of several books, such as ‘Astrophysics for People in a Hurry' and the newly revised ‘Just Visiting this Planet: More Cosmic Quandaries from Dr. Tyson's inbox'.  In this explosive conversation, he explains:  ◼️80% of Gen Z believe the stars control their life ◼️The dangerous lie we believe about life's purpose, and what to do instead ◼️Why you have 20% of the same DNA as a banana ◼️Why AI's real danger isn't what Hollywood warned you about ◼️Why simulation theory might explain every disaster on Earth (00:00) Intro (02:43) The Big Questions About the Universe and Our Existence (10:55) Why We're Not Good at Feeling Oneness With Others (15:48) Has Science Shaped Your Beliefs About Religion? (20:15) Did Humans Evolve to Believe in Something? (25:00) Changing the Way We See the Universe (30:32) Did the Loss of Your Parents Change Your Views? (35:05) Do We Live in a Simulation? (40:05) Do We Have Free Will in Our Society? (43:44) Will We Be Able to Extend Our Lives Soon? (45:57) What Happens When We Extend Everyone's Lives? (48:57) Neil deGrasse Tyson on AI (53:28) Will We Travel to Mars in Our Lifetime? (1:00:01) How Long and How Far Is It to Mars? (1:02:43) Ads (1:04:13) What Would Happen If the Earth Got Swallowed by a Black Hole? (1:07:51) Could the Sun Become a Black Hole? (1:09:06) What Happens If the Sun Freezes? (1:10:37) Every Breath You Take Contains the History of the Universe (1:15:25) Is the Universe Infinite? (1:16:34) Do Aliens Exist? (1:19:37) Why Do You Think Aliens Exist? (1:25:38) The Physics Error in *The Matrix* (1:28:22) Ads (1:30:26) The Questions We Dream Of (1:33:26) Should We Argue About Meaning? (1:37:18) Are Horoscopes Really a Thing? (1:42:15) Are You Happier If You Believe in God? (1:46:54) What's the Biggest Advice You Have for Me? (1:51:32) What Do You Think of America Right Now? (1:57:25) Do You Have Any Regrets? Follow Neil: X - https://bit.ly/47m0sAz Instagram - https://bit.ly/48E3kuT  Facebook - https://bit.ly/48VGmiL TikTok - https://bit.ly/46Y1na6 UK - You can pre-order Neil's revised book, ‘Just Visiting This Planet: Merlin Answers More Questions about Everything under the Sun, Moon and Stars', here: https://amzn.to/43cbEhB  US - You can pre-order Neil's revised book, ‘Just Visiting This Planet: Merlin Answers More Questions about Everything under the Sun, Moon and Stars', here: https://amzn.to/3Wxvsbq  The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/  ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook  ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt  ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb  ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt  ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb  Sponsors: Shopify - https://shopify.com/bartlett                                                      KetoneIQ - Visit https://ketone.com/STEVEN for 30% off your subscription order

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
1065: Do Inhaled Antibiotics Prevent VAP?

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Sep 29, 2025 3:53


Show notes at pharmacyjoe.com/episode1065. In this episode, I’ll discuss inhaled antibiotics to prevent VAP. The post 1065: Do Inhaled Antibiotics Prevent VAP? appeared first on Pharmacy Joe.

Juicebox Podcast: Type 1 Diabetes
#1634 Grand Rounds: Inhaled Insulin

Juicebox Podcast: Type 1 Diabetes

Play Episode Listen Later Sep 22, 2025 61:57


Pediatric endocrinologist Dr. Michael Haller explores inhaled insulin and the evolving approval process for children under 18. Free Juicebox Community (non Facebook) Type 1 Diabetes Pro Tips - THE PODCAST Eversense CGM Medtronic Diabetes Tandem Mobi ** twiist AID System Drink AG1.com/Juicebox Use code JUICEBOX to save 40% at Cozy Earth  CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED  or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.  ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan.  If the podcast has helped you to live better with type 1 please tell someone else how to find it!

Dr. Joseph Mercola - Take Control of Your Health
Microplastics Found to Trigger Cancer-Linked Changes in Lung Cells

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Sep 8, 2025 8:35


Microplastics were found to trigger cancer-like changes in healthy lung cells, including increased mobility, DNA damage, and activated survival pathways Inhaled particles bypass your body's defenses and embed deep in your lungs, where they silently disrupt cellular function without causing obvious inflammation A review of 31 studies confirmed that microplastics harm your lungs, gut, and reproductive organs even at exposure levels that mimic everyday life Smaller nanoplastics are especially dangerous because they cross into your bloodstream, reaching your liver, brain, and other organs where they cause long-term damage Natural strategies like psyllium, chitosan, probiotics, and autophagy-enhancing nutrients help trap and remove plastic particles before they're absorbed

The Medbullets Step 2 & 3 Podcast
Pulmonary | Inhaled Beta-Agonists

The Medbullets Step 2 & 3 Podcast

Play Episode Listen Later Aug 13, 2025 8:01


In this episode, we review the high-yield topic ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Inhaled Beta-Agonists⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Pulmonary section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

The Medbullets Step 2 & 3 Podcast
Pulmonary | Inhaled Muscarinic-Antagonists

The Medbullets Step 2 & 3 Podcast

Play Episode Listen Later Aug 12, 2025 5:26


In this episode, we review the high-yield topic ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Inhaled Muscarinic-Antagonists⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Pulmonary section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

CHEST Journal Podcasts
Inhaled Menthol for Dyspnea Relief During Cycle Exercise in COPD: A Randomized Trial

CHEST Journal Podcasts

Play Episode Listen Later Aug 1, 2025 27:05


Michele R. Schaeffer, PhD, Andreas von Leupoldt, PhD, and Daniel Langer, PhD, join CHEST® Journal Podcast Moderator, Alice Gallo De Moraes, MD, FCCP, to discuss their research into inhaled menthol as a potential treatment for dyspnea relief during cycle exercise for patients with COPD.  DOI: 10.1016/j.chest.2025.03.002 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Paul Saladino MD podcast
263. Why I Changed My Mind About Hydrogen Water (with Tyler LeBaron)

Paul Saladino MD podcast

Play Episode Listen Later Jul 28, 2025 121:22


Ever wondered why a molecule as simple as hydrogen could influence everything from Parkinson's to metabolic syndrome? We explored how molecular hydrogen selectively targets only the most harmful free radicals while leaving beneficial ones alone, making it fundamentally different from every other antioxidant supplement gathering dust in your cabinet.The six-month metabolic syndrome study particularly caught my attention: participants drinking hydrogen water saw improvements in glucose levels, HbA1c, inflammation markers, and even lost weight – with no diet changes or exercise requirements.Tyler breaks down why those expensive alkaline water machines aren't doing what you think (spoiler: it's not about pH), why hydrogen inhalation requires serious safety considerations, and exactly how to dose hydrogen water for maximum benefit.And on top of all this, we tackle why this primordial molecule – literally present since the beginning of the universe – seems almost designed to work with human biology, and why megadoses of vitamins C and E can actually harm exercise performance while hydrogen acts as a fine-tuning modulator.Timestamps:0:00 Hydrogen's effects on major diseases2:45 Six-month metabolic syndrome study results5:15 Hydrogen only targets toxic radicals6:08 Divine properties of hydrogen molecule10:12 Basic chemistry of oxidation and reduction15:30 Dangers of excessive antioxidants23:45 How hydrogen modulates antioxidant systems47:20 Hydrogen production in your gut56:30 Inhaled vs drinking hydrogen water61:15 Explosive dangers of hydrogen inhalation71:30 Therapeutic dosing for hydrogen water85:45 Debunking alkaline and structured water94:30 Tyler's elite athletic performance secretsDisclaimer:Dr. Paul Saladino received his medical degree from the University of Arizona Medical School. His use of "doctor" or "Dr." in relation to himself solely refers to that degree. Dr. Saladino is a licensed physician in California, but he no longer practices in any state and does not see patients so he can focus on educating people full time.This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, or prescription. It does not create a doctor-patient relationship between Dr. Saladino and you. Always consult your physician before making any health decisions.

Intelligent Medicine
Intelligent Medicine Radio for July 19, Part 2: Hot Baths v. Saunas

Intelligent Medicine

Play Episode Listen Later Jul 21, 2025 44:09


Advice for liver fibrosis; A caller with a 30 year history of fatigue may need adrenal support; Air filters reduce classroom absenteeism; Inhaled insulin may free diabetics from injections; High blood sugar, not just waning testosterone, the culprit in male sexual decline; Hot baths beat saunas for cardiovascular benefits; Monday stress is real—even for retirees.

Diabetes Connections with Stacey Simms Type 1 Diabetes
In the News...Top Stories from ADA and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

Play Episode Listen Later Jun 27, 2025 7:48


It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: loads of news from American Diabetes Association Scientific Sessions, GLP1 for T1D, Tech updates, diabetes in space, and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Top story – looking back at The American Diabetes Association Scientific Sessions conference. I won't recap everything here – but I'll link up to a few more comprehensive article. Here's just a taste! XX A single infusion of a new stem cell-based treatment helped 10 out of 12 people with severe type 1 diabetes stop using insulin, researchers report. The treatment, called zimislecel, was made by Vertex Pharmaceuticals. It's an infusion of lab-grown islet cells. A year after getting the therapy, 10 patients no longer needed insulin shots. The other two were able to reduce how much insulin they needed.  The treatment requires patients to take immunosuppressive drugs, which may raise the risk of infections or cancer in the long run, experts said. https://www.usnews.com/news/health-news/articles/2025-06-24/stem-cell-treatment-may-free-some-with-type-1-diabetes-from-insulin XX New study shows inhaled insulin is safe and effective for children with type 1 diabetes. This is Mannkind's Afrezza, which takes the place of rapid-acting mealtime insulin. Findings indicate that inhaled insulin delivers glycemic control comparable to injected rapid-acting insulin. Inhaled insulin was also associated with less weight gain and slightly higher patient and parent preference scores. These findings add to outcomes shared from INHALE 1 late last year. Based on the findings of the inhaled insulin study, MannKind looks to seek FDA approval to expand Afrezza's indication to children. The company also aims to evaluate inhaled insulin at diagnosis and in automated insulin delivery systems in additional studies. https://www.drugdeliverybusiness.com/study-mannkind-inhaled-insulin-safe-effective-children/ XX Positive outcomes in two different studies looking at GLP 1 medications for type 1. Semaglutide – brand name Ozempic or Wegovy - reduced glucose levels and weight among patients with type 1 diabetes and obesity. 26-week, double-blind trial of 72 adults, those taking Ozempic spent More than 70% time spent in sensor glucose range (70-180 mg/dL) Less than 4% time spent in hypoglycemia (

Molecule to Market: Inside the outsourcing space
The GM focused on inhaled & nasal drugs

Molecule to Market: Inside the outsourcing space

Play Episode Listen Later Jun 27, 2025 46:03


In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Gemma Budd, General Manager at Nanopharm. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Gemma, covering: Why being in an overlay strategic, future-focused role led her to make the tough decision to move on Identifying the joy of solving problems for customers in service-based businesses Why her holistic experience led to the GM role...and the reality in becoming the leader The factors driving growth for inhalation delivery for nasal and pulmonary routes Being a niche player in a global market - why clients don't care where you are when you know what you're doing With a background in biomedical science, Gemma has built her career over the past 15 years by leveraging and expanding that knowledge in the pharmaceutical and medical devices industry. She has worked in companies providing analytical and formulation development services, materials science consultancy and manufacturing of drug delivery systems – primarily in commercial and technical roles.  She is currently the General Manager of Nanopharm, a specialist CRO focusing on developing nasally administered and inhaled drug products for pharmaceutical companies worldwide, through her team of 75 employees in the UK. She is focused on ensuring the business continually delivers, innovates and evolves in their niche space to ensure their clients benefit from their expertise that is not widely available in the industry, developing both exceptional talent and unique technology platforms, and ensuring they combine to deliver high quality services to help get drugs to patients quickly, safely and effectively. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Air Health Our Health
Inhaled Microplastics with the Lorax of the Thorax

Air Health Our Health

Play Episode Listen Later Jun 2, 2025 27:50


Welcome to the last Air Health Our Health podcast of Season Five. This is a collaboration with the American Thoracic Society's Breathe Easy podcast, of which I am a new host. We produce over 450 million tons of plastic each year, the majority of which accumulates in the environment- it is vital to understand how that impacts us. For today's episode, I interview Dr Adam Soloff, PhD a researcher at the UPMC Hillman Cancer Center of the University of Pittsburgh in the department of cardiothoracic surgery and immunology. He describes himself as the “Lorax of the Thorax” and walks us through research on how ever-present microplastics that we inhale can seed tissues throughout the body and what that does to our immune system. So what can you do? Look at where you are using plastic in your own life and see if you can replace it with a healthier option. Few options here.Find out what can be done to reduce plastics in your community. Look up your members of Congress and share with them your concern about dismantling important science-based support for health at the federal level, whether the NIH, EPA, CDC, VA and more. Then, look up your city councilperson and state legislator to ask what they are doing to help prevent plastic pollution and find out what you can do to help.Finally, be sure to enjoy the beautiful planet on which we all live and take at least one step to keep it beautiful and healthy. Find what you can do and do it. None of us have to do everything, but we can all do something.

Galactic Horrors
I Inhaled a Dead Alien's Memories. It's Resurrecting a Civilization Through Me | Sci-Fi Creepypasta

Galactic Horrors

Play Episode Listen Later May 16, 2025 44:02


Germ & Worm
47: Hot Snot! The cold truth about your nasal discharge

Germ & Worm

Play Episode Listen Later May 6, 2025 34:17


Yassou! Today, travel medicine specialists Drs. Paul Pottinger ("Germ") & Chris Sanford ("Worm") answer your travel health questions:Inhaled steroids and antibiotics for measles, please say it ain't so!My sister's cats have fleas! What can I do when I visit her?Salt water–safe to drink in any amount?Food on the floor: Is the 5-second rule true?How can I prevent sea sickness on the ferry from Spain to Morocco?What about the color of my snot–does it reveal viral vs bacterial causes of my sinusitis?Can I trust Google Maps?Can I pleeeeease get immunized against dengue?We hope you enjoy this podcast! If so, please follow us on the socials @germ.and.worm, subscribe to our RSS feed and share with your friends! We would so appreciate your rating and review to help us grow our audience. And, please send us your questions and travel health anecdotes: germandworm@gmail.com.Our Disclaimer: The Germ and Worm Podcast is designed to inform, inspire, and entertain. However, this podcast does NOT establish a doctor-patient relationship, and it should NOT replace your conversation with a qualified healthcare professional. Please see one before your next adventure. The opinions in this podcast are Dr. Sanford's & Dr. Pottinger's alone, and do not necessarily represent the opinions of the University of Washington or UW Medicine.

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
1023: The Dose of Inhaled Tranexamic Acid For Nonmassive Hemoptysis

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later May 5, 2025 2:54


Show notes at pharmacyjoe.com/episode1023. In this episode, I'll discuss the dose of inhaled tranexamic acid used for nonmassive hemoptysis. The post 1023: The Dose of Inhaled Tranexamic Acid For Nonmassive Hemoptysis appeared first on Pharmacy Joe.

The 2TYPEONES Podcast
#275: Inhaled Insulin Along Side Insulin Pumps & MDI

The 2TYPEONES Podcast

Play Episode Listen Later May 3, 2025 32:33


Hey Diabuddy thank you for listening to show, send me some positive vibes with your favorite part of this episode.In today's episode, I brake down my experience with an 8 month experiment using insulin pumps and MDI (manual Daily Injections) along side Afrezza (inhaled Insulin). I talk about the benefits and disadvantages that I discovered using using pumps and injections and which I prefer. Diabetes Nerd - Ginger Vieira - Afrezza Inhaled InsulinCoach Ken's Resources:Website: www.simplifyingdiabetes.comNewsletter Sign Up"More Than A1C" - My Signature Coaching ProgramThe Diabetes Nutrition Master CourseThe 5-Pillars Of Diabetes Success WorksheetSet Up a Free Call...Apparel StoreSupport & Donate To The PodcastThe T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for Diabetes research. Once enrolled, Registry participants have the opportunity to sign up for other studies on various topics related to type 1 diabetes.You can make an impact on the future of Diabetes now! Fill out an online  survey and gain access to tons of new research and the online portal. It only takes 10-15 minutes.Have a question, send me a DM or email. I'd love to connect and answer any questions you have.You can find the show  on any platform you listen to your podcasts!Don't forget to click on that subscribe button and leave a 5-star review, so you're notified when new episode drop every week.Questions about diabetes, don't hesitate to reach out:Instagram: @CoachK3NInstagram: @thehealthydiabeticpodFacebook: @Simplifying Life With DiabetesEmail: ken@simplifyingdiabetes.comPodcast Disclaimer: Nothing that you hear on The Healthy Diabetic Podcast should be considered medical advice or otherwise; please always consult your medical TEAM before making any changes to your Diabetes management.Support the show

The Incubator
#297 - [Journal Club Shorts] -

The Incubator

Play Episode Listen Later Apr 6, 2025 14:16


Send us a textResponse to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension.Baczynski M, Weisz D, Thomas L, Fevrier S, Castaldo M, Soraisham A, Hyderi A, Agarushi R, Bhattacharya S, Lalitha R, Sidhu A, Abdul Wahab MG, Altit G, Hébert A, Louis D, Elsayed Y, Mitra S, Deshpande P, Kharrat A, Zhu F, Ting J, Yoon E, Shah PS, Jain A; Canadian Neonatal Network Investigators.JAMA Netw Open. 2025 Feb 3;8(2):e2458843. doi: 10.1001/jamanetworkopen.2024.58843.PMID: 39928335 Free PMC article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
1013: A Setback For the Use of Inhaled Sedation in the ICU

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Mar 31, 2025 3:32


Show notes at pharmacyjoe.com/episode1013. In this episode, I'll discuss inhaled sedation for ICU patients with acute respiratory distress syndrome. The post 1013: A Setback For the Use of Inhaled Sedation in the ICU appeared first on Pharmacy Joe.

JAMA Author Interviews: Covering research in medicine, science, & clinical practice. For physicians, researchers, & clinician
Inhaled Sedation With Sevoflurane for Acute Respiratory Distress Syndrome (ARDS)

JAMA Author Interviews: Covering research in medicine, science, & clinical practice. For physicians, researchers, & clinician

Play Episode Listen Later Mar 18, 2025 18:08


ARDS, which is characterized by hypoxemic respiratory failure and inflammatory injury to the lungs, has a mortality rate of 30% to 40%. Balasubramanian Venkatesh, MD, of the George Institute for Global Health joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the effects of inhaled sedation with sevoflurane for patients with moderate to severe ARDS. Related Content: Sevoflurane Sedation in Acute Respiratory Distress Syndrome Inhaled Sedation in Acute Respiratory Distress Syndrome

ms md global health sedation ards inhaled acute respiratory distress syndrome george institute
Heaving Bosoms
Egotistical Puckboy by Eden Finley and Saxon James (Part 1) | 372.1

Heaving Bosoms

Play Episode Listen Later Mar 3, 2025 67:53


Hey HBs! It's enthusiastic gremlin hour over here at HBHQ because we're recapping Egotistical Puckboy by Eden Finley and Saxon James! It's book one in a series both pals INHALED with glee. They're basically honorary members of the Queer Collective (don't believe Tripp, it's a thing). Bonus Content: Mel is ON ONE this episode. It's all gremlin all the time. Want to support the show? Rate and review us on your favorite podcast app! It super helps the algorithm connect us to new listeners.  Want more of us? Check out our PATREON! This Friday, we're doing a Quickie on the next few books in the Puckboys series by Eden Finley and Saxon James!! Credits: Theme Music: Brittany Pfantz  Art: Author Kate Prior Want to tell us a story, ask about advertising, or anything else? Email: heavingbosomspodcast (at) gmail  Follow our socials:  Instagram @heavingbosoms Tiktok @heaving_bosoms  Facebook group: the Heaving Bosoms Geriatric Friendship Cult The above contains affiliate links, which means that when purchasing through them, the podcast gets a small percentage without costing you a penny more.

AP Audio Stories
Pope had coughing fit, inhaled vomit and his prognosis remains guarded, Vatican says

AP Audio Stories

Play Episode Listen Later Feb 28, 2025 0:48


AP correspondent Donna Warder has an update on Pope Francis' medical condition.

The Medbullets Step 1 Podcast
Neurology | Inhaled Anesthetics

The Medbullets Step 1 Podcast

Play Episode Listen Later Feb 15, 2025 11:31


In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Inhaled Anesthetics ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Neurology section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

The 2TYPEONES Podcast
#256: Gingers Bad Mood Monday - Inhaled Insulin (Afrezza)

The 2TYPEONES Podcast

Play Episode Listen Later Jan 31, 2025 44:45


Hey Diabuddy thank you for listening to show, send me some positive vibes with your favorite part of this episode.In today's episode, I sit down with Ginger Vieira, a T1D, freelance Diabetes writer, Mother, and Diabetes author. Many of you have been asking me more about inhaled insulin (Afrezza). So, I thought this would be a great opportunity to do a deep dive into Afrezza and debunk some of the myths behind this incredible fast-acting medication. Ginger Vieira ResourcesWebsiteDiabetes Nerd - YouTube PageType 1 Tea - Podcast  BooksInstagramLinkedinOther Episodes With Ginger#244#144#137Coach Ken's Resources:Website: www.simplifyingdiabetes.comNewsletter Sign Up"More Than A1C" - My Signature Coaching ProgramThe Diabetes Nutrition Master CourseThe 5-Pillars Of Diabetes Success WorksheetDecember (2024) Stronger Together With T1D Get-TogetherSupport & Donate To The PodcastHave a question, send me a DM or email. I'd love to connect and answer any questions you have.You can find the show  on any platform you listen to your podcasts!Don't forget to click on that subscribe button and leave a 5-star review, so you're notified when new episode drop every week.Questions about diabetes, don't hesitate to reach out:Instagram: @CoachK3NInstagram: @thehealthydiabeticpodFacebook: @Simplifying Life With DiabetesEmail: ken@simplifyingdiabetes.comPodcast Disclaimer: Nothing that you hear on The Healthy Diabetic Podcast should be considered medical advice or otherwise; please always consult your medical TEAM before making any changes to your Diabetes management.Support the show

Diabetes Connections with Stacey Simms Type 1 Diabetes
In the News... Inhaled Insulin Studied for Kids, Dexcom Launches AI, App for Driving & T1D, and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

Play Episode Listen Later Dec 20, 2024 6:25


It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Mannkind releases info about it's Afrezza pediatric studies, Dexcom launches AI tech with Stelo, Health Canada approves Tandem/Dexcom G7, diabetes drug may help sleep apnea, an app in development to help drivers with T1D and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom  Edgepark Medical Supplies Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens  Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Mannkid expects to talk to the FDA about Afrezza inhaled insulin for pediatric approval early in 2025. The company just announced six-month results from its Phase 3 INHALE-1 study of kids aged 4-17 with type 1 or type 2 diabetes comparing either inhaled pre-meal insulin or multiple daily injections (MDI) of rapid-acting insulin analog, both in combination with basal insulin. A 26-week extension phase in which all remaining MDI patients were switched to inhaled insulin is ongoing. HbA1c change over 26 weeks exceeded the prespecified non-inferiority margin of 0.4% (0.435%), largely driven by the variability of a single patient who did not adhere to the study protocol. A modified ITT (mITT) analysis, which excluded this subject, did not exceed the predetermined threshold of 0.4% (0.370%), thereby establishing the non-inferiority of Afrezza to MDI, which was the primary endpoint of the study. Over 26 weeks of treatment, there were no differences in lung function parameters between the treatment groups, There were no differences between groups or concerns in other safety measures, including hypoglycemia. https://www.medscape.com/viewarticle/inhaled-insulin-benefits-kids-diabetes-too-2024a1000nex   XX Dexcom announces the use of AI for its Stelo platform. The company says the new Dexcom GenAI platform will analyze individual health data patterns to reveal a direct association between lifestyle choices and glucose levels while providing actionable insights to help improve metabolic health. Stelo users will start seeing the features this week. The AI is modeled after Google Cloud's Vertex AI and Gemini models. We'll hear more about this in January – Dexcom will be part of a panel at the Consumer Electronics Show about AI and healthcare. BTW this press release is the first time I've seen what seems to be a new slogan for Dexcom – Discover What You're Made Of. https://www.businesswire.com/news/home/20241217011997/en/Dexcom-Launches-the-First-Generative-AI-Platform-in-Glucose-Biosensing XX Staying with Dexcom, users report that the geofencing issue we reported on seems to be resolved. Previously, if you had an issue with Dexcom G7 outside of your home country, you couldn't reinstall or use the app without customer support. With the latest iOS and Android G7 apps, this seems to be resolved. This is according to the folks in the DIY community who first brought it to my attention.   XX Interesting insulin development to watch. Egypt approves EVA Pharma's insulin drug products, which is a collbaration between Eli llly and EVA, an Egyptian company. The Egyptian Drug Authority approved the insulin glargine injection manufactured by EVA Pharma through a collaboration with Eli Lilly and Company (NYSE: LLY). Launched in 2022, the collaboration aims to deliver a sustainable supply of high-quality, affordable human and analog insulin to at least one million people annually living with type 1 and type 2 diabetes in low- to middle-income countries (LMICs), most of which are in Africa.   Lilly has been supplying its active pharmaceutical ingredient (API) for insulin to EVA Pharma at a significantly reduced price and providing pro-bono technology transfer to enable EVA Pharma to formulate, fill and finish insulin vials and cartridges. This collaboration is part of the Lilly 30x30 initiative, which aims to improve access to quality health care for 30 million people living in resource-limited settings annually by 2030. https://www.prnewswire.com/news-releases/lilly-and-eva-pharma-announce-regulatory-approval-and-release-of-locally-manufactured-insulin-in-egypt-302333269.html     XX Can we add treating sleep apnea to the list of applications for terzepatide? That's the generic for Zepbound and Mounjaro. Phase 3 study shows that 10- and 15-milligram injections of Zepbound "significantly reduced the apnea-hypopnea index" among those who have obesity and moderate-to-severe obstructive sleep apnea. Eli Lilly said there was nearly a 20% reduction in weight among those in the trials. The company said it plans to submit its findings to the Food and Drug Administration and other global regulatory agencies beginning mid-year. https://www.aol.com/popular-weight-loss-drug-could-131507702.html   XX Health Canada okays Tandem's tslim X2 with Dexcom G7 and G6 making it the first and only insulin pump in Canada that is integrated with both Dexcom sensors. Now, t:slim X2 users in Canada can experience even more choice when it comes to CGM compatibility, along with the option to spend more time in closed loop with Dexcom G7's 30-minute sensor warm-up time, faster than any other CGM on the market.3 In addition, t:slim X2 users who pair Dexcom G7 with an Apple smartwatch4 can see their glucose numbers directly from their watch without having to access their pump or smartphone4. Tandem will email all in-warranty t:slim X2 users in Canada with instructions on how to add the new compatibility feature free of charge via remote software update. t:slim X2 pumps pre-loaded with the updated software will begin shipping to new customers in early January 2025.   To check coverage and start the process of getting a Tandem insulin pump, please visit tandemdiabetes.ca. https://www.businesswire.com/news/home/20241210731189/en/Tandem-tslim-X2-Insulin-Pump-Now-Compatible-with-Dexcom-G7-CGM-in-Canada XX A federal jury on Tuesday awarded Insulet $452 million in its patent skirmish with EOFlow over insulin patch pumps. The jury awarded Insulet $170 million in compensatory damages from EOFlow and an additional $282 million in exemplary damages for willful and malicious misappropriation. A judge has not yet entered a judgment on the decision. Insulet filed a lawsuit in the U.S. District Court for the District of Massachusetts in 2023, claiming EOFlow copied patented components of its Omnipod insulin pumps. In October 2023, the Massachusetts district court issued a preliminary injunction against EOFlow. Following that decision, Medtronic called off plans to buy EOFlow for about $738 million.   A federal appeals court later overturned the preliminary injunction, and EOFlow resumed selling its devices in Europe. The company recently defended against a separate injunction filed by Insulet in Europe's Unified Patent Court, according to Korea Biomedical Review, an online English newspaper based in Seoul, South Korea.   The Massachusetts jury found this week that EOFlow and CEO Jesse Kim, as well as two of three former Insulet employees who were named as defendants in the lawsuit, misappropriated Insulet's trade secrets.   Insulet CEO Jim Hollingshead said the company is “extremely pleased with the jury's verdict.” EOFlow did not immediately respond to a request for comment. https://www.medtechdive.com/news/insulet-eoflow-jury-verdict-patent-lawsuit/734745/ XX A tele-education program for health care providers who treat people with diabetes resulted in significant improvements in patient outcomes, including better blood sugar levels and increased use of medical devices to manage the disease, a University of Florida study finds. Led by researchers in the UF College of Public Health and Health Professions and the UF College of Medicine, the program used the Extension for Community Health Care Outcomes model, which has been adopted worldwide to train clinicians who treat patients with a variety of conditions. Known as Project ECHO, this is one of the first to demonstrate patient benefits for the program in a large, randomized trial. The findings appear in the journal Diabetes Care. https://ufhealth.org/news/2024/clinician-training-program-leads-to-better-outcomes-for-patients-with-diabetes XX New app under development to make driving safer for people with diabetes. Diabetes Driving Pal says it will use CGM data and guide you while you are driving without any annoying alerts. Guidance/suggestions will be on your car dashboard so that you don't have to look at phone and it will be very individualized and actionable. In a study last year, ~70% of people have reported (5% reported accident) to have at least one low blood sugar while driving and most reported that CGM alerts were not enough to protect them. We are hoping to start beta testing in a few months. We are trying to raise the fund to develop this product. We need your support. For more information, please visit: https://lnkd.in/gTDhnDc4 XX I'm also going to link to the top ten most read diabetes and endocrinology stories of 2024 from Medscape. This is almost all GLP-1 related.. and mostly for people with type 2. https://www.medscape.com/viewarticle/icymi-top-10-diabetes-endocrinology-stories-2024-2024a1000n6u?&icd=login_success_email_match_fpf XX That's it for the last In the News of 2024! Don't miss out episode next week with a look ahead to what we're watching in 2025. I'm SS I'll see you back here soon…

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
980: Adjunctive Inhaled Antibiotics for ICU Patients with Pneumonia and Invasive Ventilation

The Elective Rotation: A Critical Care Hospital Pharmacy Podcast

Play Episode Listen Later Dec 5, 2024 3:20


Show notes at pharmacyjoe.com/episode980. In this episode, I'll discuss adjunctive inhaled antibiotics for ICU patients with pneumonia and invasive ventilation. The post 980: Adjunctive Inhaled Antibiotics for ICU Patients with Pneumonia and Invasive Ventilation appeared first on Pharmacy Joe.

The Rounds Table
Episode 96 - The Balance Trial and Inhaled Amikacin to Prevent VAP

The Rounds Table

Play Episode Listen Later Nov 28, 2024 20:06


Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers - the Balance Trial and the role of inhaled amikacin in preventing VAP. Two papers, here we go!Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia (0:00 – 8:24).Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (8:24 – 17:24).And for the Good Stuff:The Tragically Hip: No Dress Rehearsal (17:24 – 18:30).www.powercalc.ca (18:30 – 20:06)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.
Asthma Inhaled Reliever Therapies, Asymptomatic Aortic Valve Replacement, Review on Peptic Ulcer Disease, and more

JAMA Editors' Summary: On research in medicine, science, & clinical practice. For physicians, researchers, & clinicians.

Play Episode Listen Later Nov 1, 2024 9:27


Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from October 26-November 1, 2024.

The 2TYPEONES Podcast
#224: Inhaled Insulin & the Implantable CGM - Paul

The 2TYPEONES Podcast

Play Episode Listen Later Oct 1, 2024 76:51


In today's episode, I sat down with Paul, T1D and endurance enthusiast. Paul and I talk about growing up at a early age with Diabetes, pre-technology. We also discuss Eversense, the implantable CGM and Affrezza, inhaled insulin. Paul's InstagramCoach Ken's Resources:Website: www.simplifyingdiabetes.comNewsletter Sign Up"More Than A1C" - My Signature Coaching ProgramThe Diabetes Nutrition Master CourseThe 5-Pillars Of Diabetes Success WorksheetSupport & Donate To The PodcastThe T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for Diabetes research. Once enrolled, Registry participants have the opportunity to sign up for other studies on various topics related to type 1 diabetes.You can make an impact on the future of Diabetes now! Fill out an online  survey and gain access to tons of new research and the online portal. It only takes 10-15 minutes.Don't forget to check out Ancient Bliss an herbal supplement company.Use Discount Code KEN20 for 20% off at check out.Have a question, send me a DM or email. I'd love to connect and answer any questions you have.You can find the show  on any platform you listen to your podcasts!Don't forget to click on that subscribe button and leave a 5-star review, so you're notified when new episode drop every week.Questions about diabetes, don't hesitate to reach out:Instagram: @CoachK3NInstagram: @thehealthydiabeticpodTwitter: @thehealthydpodTik Tok: @thehealthydiabeticpodFacebook: @Simplifying Life With DiabetesEmail: ken@simplifyingdiabetes.comPodcast Disclaimer: Nothing that you hear on The Healthy Diabetic Podcast should be considered medical advice or otherwise; please always consult your medical TEAM before making any changes to your Diabetes management.Support the show

The Incubator
#236 - [Journal Club Shorts] -

The Incubator

Play Episode Listen Later Sep 1, 2024 15:43


Send us a textRetrospective study of preterm infants exposed to inhaled nitric oxide in Kaiser Permanente Southern California: morbidity, mortality and follow-up.Bhatt DR, Braun D, Dizon RA, Shi JM, Weerasinghe S, Sabio A, Reddy S, Lee HC, Ramanathan R, Lakshminrusimha S.J Perinatol. 2024 Jul 18. doi: 10.1038/s41372-024-02051-w. Online ahead of print.PMID: 39025953As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Pharmacy to Dose: The Critical Care Podcast
Status Epilepticus: Part II

Pharmacy to Dose: The Critical Care Podcast

Play Episode Listen Later Aug 26, 2024 85:00


Status Epilepticus: Part II Special Guest: Jason Vilar, PharmD, BCCCP @TheBrainPharmD   03:40 – Definitions/Terminology 14:30 – Landmark status epilepticus (SE) literature 21:30 – Emergent ASM SE pharmacotherapy 26:00 – DDI management/TDM 33:55 – Refractory status epilepticus (RSE) treatment 48:15 – Medication safety considerations and weaning 58:00 – EEGs for PharmD's 68:10 – Inhaled anesthetics 74:30 – Studies on the horizon/take-home points   Reference List: https://pharmacytodose.com/wp-content/uploads/2024/08/status-epilepticus-part-ii-references.pdf   PharmacyToDose.Com @PharmacyToDose PharmacyToDose@Gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Juicebox Podcast: Type 1 Diabetes
#1266 Dr. Tom Blevins on Inhaled Insulin

Juicebox Podcast: Type 1 Diabetes

Play Episode Listen Later Jul 30, 2024 70:35


Dr. Blevins is back to talk about the inhaled insulin called Afrezza. JUICE CRUISE 2025 Screen It Like You Mean It Eversense CGM Hungryroot eat healthy Learn about the Medtronic Champions This BetterHelp link saves 10% on your first month of therapy Try delicious AG1 - Drink AG1.com/Juicebox I Have Vision Use code JUICEBOX to save 30% at Cozy Earth  Get Gvoke HypoPen CONTOUR NextGen smart meter and CONTOUR DIABETES app Learn about the Dexcom G6 and G7 CGM Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED  or call 888-721-1514 Learn about Touched By Type 1 Take the T1DExchange survey *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.  How to listen, disclaimer and more Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan.  If the podcast has helped you to live better with type 1 please tell someone else how to find the show and consider leaving a rating and review on Apple Podcasts. Thank you! The Juicebox Podcast is not a charitable organization.