Podcast appearances and mentions of nat rev endocrinol

Dr. Goodson grew up in Missouri and graduated from the University of Missouri Columbia and Harvard Medical School. He trained as a general surgeon and specialized in breast surgery before it was a recognized field. He was a member of the research group that established breast conservation, i.e., lumpectomy, as the preferred treatment for early breast cancer. Recognizing that he was treating more young women with breast cancer, he joined with Dr. Shanaz Dairkee in 2005 to investigate how common environmental chemicals such as BPA, methylparaben, PFOA, etc. disrupt the normal biology of non-cancerous, human breasts. He has been a professor at the University of California San Francisco and a Senior Scientist at the California Pacific Medical Center Research Institute. He is a fellow of the American College of Surgeons, a member of the American Society for Clinical Oncology, and a spokesperson for The Halifax Project. In addition to research, he enjoys photography, writing, and creating hand-drawn animation as on his website, www.drwilliamgoodson.com A Ternary Mixture of Common Chemicals Perturbs Benign Human Breast Epithelial Cells More Than the Same Chemicals Do Individually. Dairkee SH, Luciani-Torres G, Moore DH, Jaffee IM, Goodson WH 3rd. Toxicol Sci. 2018 Sep 1;165(1):131-144. doi: 10.1093/toxsci/kfy126. PMID: 29846718 Free PMC article.   Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C... See abstract for full author list ➔ Carcinogenesis. 2015 Jun;36 Suppl 1(Suppl 1):S254-96. doi: 10.1093/carcin/bgv039. PMID: 26106142 Free PMC article.   Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT. Nat Rev Endocrinol. 2020 Jan;16(1):45-57. doi: 10.1038/s41574-019-0273-8. Epub 2019 Nov 12. PMID: 31719706 Free PMC article.   Exposure to the polyester PET precursor--terephthalic acid induces and perpetuates DNA damage-harboring non-malignant human breast cells. Luciani-Torres MG, Moore DH, Goodson WH 3rd, Dairkee SH. Carcinogenesis. 2015 Jan;36(1):168-76. doi: 10.1093/carcin/bgu234. Epub 2014 Nov 19. PMID: 25411358 Free PMC article.   The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them. Smith MT, Guyton KZ, Kleinstreuer N, Borrel A, Cardenas A, Chiu WA, Felsher DW, Gibbons CF, Goodson WH 3rd, Houck KA, Kane AB, La Merrill MA, Lebrec H, Lowe L, McHale CM, Minocherhomji S, Rieswijk L, Sandy MS, Sone H, Wang A, Zhang L, Zeise L, Fielden M. Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):1887-1903. doi: 10.1158/1055-9965.EPI-19-1346. Epub 2020 Mar 9. PMID: 32152214 Free PMC article.   Testing the low dose mixtures hypothesis from the Halifax project. Goodson WH, Lowe L, Gilbertson M, Carpenter DO. Rev Environ Health. 2020 Aug 24;35(4):333-357. doi: 10.1515/reveh-2020-0033. Print 2020 Nov 18. PMID: 32833669 Review.   Using the Key Characteristics of Carcinogens to Develop Research on Chemical Mixtures and Cancer. Rider CV, McHale CM, Webster TF, Lowe L, Goodson WH 3rd, La Merrill MA, Rice G, Zeise L, Zhang L, Smith MT. Environ Health Perspect. 2021 Mar;129(3):35003. doi: 10.1289/EHP8525. Epub 2021 Mar 30. PMID: 33784186 Free PMC article.   Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells. Dairkee SH, Luciani-Torres MG, Moore DH, Goodson WH 3rd. Carcinogenesis. 2013 Mar;34(3):703-12. doi: 10.1093/carcin/bgs379. Epub 2012 Dec 7. PMID: 23222814 Free PMC article.   Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women. Goodson WH 3rd, Luciani MG, Sayeed SA, Jaffee IM, Moore DH 2nd, Dairkee SH. Carcinogenesis. 2011 Nov;32(11):1724-33. doi: 10.1093/carcin/bgr196. Epub 2011 Sep 1. PMID: 21890461 Free PMC article.  

孕期不要亂用止痛藥！教你如何保護寶寶！ 安胎又健康，教你孕婦如何正確使用止痛藥！ 使用過量會造成胎兒有什麼樣的影響呢? 如何快速的解讀原文文獻的小方法!! 參考文獻：Bauer, A.Z., Swan, S.H., Kriebel, D. et al. Paracetamol use during pregnancy — a call for precautionary action. Nat Rev Endocrinol (2021). https://doi.org/10.1038/s41574-021-00553-7

In this episode the Endocrine Surgery team at BTK goes over two cases to review the American Association of Endocrine Surgeons Guidelines for Adrenalectomy.  Dr. Michael Yeh is a Professor of Surgery at UCLA and serves as Section Chief of the UCLA Endocrine Surgery program which he established.  Dr. Masha Livhits is an Assistant Professor of Surgery at UCLA and works in the Endocrine Surgery Department Dr. James Wu is an Assistant Professor of Surgery at UCLA and works in the Endocrine Surgery Department  Dr. Na Eun Kim is an Endocrine Surgery Fellow at UCLA in his first year of fellowship Dr. Rivfka Shenoy is a PGY-5 General Surgery Resident at UCLA who has completed two years of research  Dr. Max Schumm is a PGY-5 General Surgery Resident at UCLA who has completed two years of research. He is a future endocrine surgeon.  Important Papers  Yip L, Duh QY, Wachtel H, Jimenez C, Sturgeon C, Lee C, Velázquez-Fernández D, Berber E, Hammer GD, Bancos I, Lee JA, Marko J, Morris-Wiseman LF, Hughes MS, Livhits MJ, Han MA, Smith PW, Wilhelm S, Asa SL, Fahey TJ 3rd, McKenzie TJ, Strong VE, Perrier ND. American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary. JAMA Surg. 2022 Oct 1;157(10):870-877. doi: 10.1001/jamasurg.2022.3544. PMID: 35976622; PMCID: PMC9386598. Schumm M, Hu MY, Sant V, Kim J, Tseng CH, Sanz J, Raman S, Yu R, Livhits M. Automated extraction of incidental adrenal nodules from electronic health records. Surgery. 2023 Jan;173(1):52-58. doi: 10.1016/j.surg.2022.07.028. Epub 2022 Oct 4. PMID: 36207197. M. Conall Dennedy, Anand K. Annamalai, Olivia Prankerd-Smith, Natalie Freeman, Kuhan Vengopal, Johann Graggaber, Olympia Koulouri, Andrew S. Powlson, Ashley Shaw, David J. Halsall, Mark Gurnell, Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas, The Journal of Clinical Endocrinology & Metabolism, Volume 102, Issue 3, 1 March 2017, Pages 786–792, https://doi.org/10.1210/jc.2016-2718 Amar, L., Pacak, K., Steichen, O. et al. International consensus on initial screening and follow-up of asymptomatic SDHx mutation carriers. Nat Rev Endocrinol 17, 435–444 (2021). https://doi.org/10.1038/s41574-021-00492-3 **Fellowship application link: https://forms.gle/PiKM2MMQpE5jSAeW7 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out other endocrine episodes here: https://behindtheknife.org/podcast-category/endocrine/

Vitamin C landet im Urin, Vitamin D-Mangel ist ein Rechenfehler — Für allgemein gesunde Erwachsene nicht empfohlen. Moyer VA; US Preventive Services Task Force. Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med. 2014;160(8):558-564. Schädlich Hohe Dosen Beta-Carotin, Folsäure, Vitamin E oder Selen schädlich: erhöhter Sterblichkeit, Krebs Schlaganfall Rautiainen S, Manson JE, Lichtenstein AH, Sesso HD. Dietary supplements and disease prevention: a global overview. Nat Rev Endocrinol. 2016;12(7):407-420. Besser aus gesunder, ausgewogener Ernährung NEM kein Ersatz für gesunde ausgewogene Ernährung. Mikronährstoffe in Lebensmitteln in der Regel besser aufgenommen plus weniger potenzielle Nebenwirkungen Rautiainen S, Manson JE, Lichtenstein AH, Sesso HD. Dietary supplements and disease prevention: a global overview. Nat Rev Endocrinol. 2016;12(7):407-420 Marra MV, Boyar AP. Position of the American Dietetic Association: nutrient supplementation. J Am Diet Assoc. 2009;109(12):2073-2085. Vitamin B12 Indiziert Perniziösen Anämie (Blutarmut), intramuskulär Verminderte Aufnahme (IF), Gastritis (Magenschleimhautentzündung), vermindertes Angebot (Alkoholismus) Langzeitanwendung von AM wie Protonenpumpenhemmer und Metformin https://www.deutsche-apotheker-zeitung.de/daz-az/2010/daz-24-2010/vitamin-b12-spiegel-sinkt-unter-metformin Vitamin D Kein Vitamin Pro-Hormon, Cholecalciferol, über UVB-Licht und Wärme in der Haut aus einer Vorstufe gebildet in Leber und Niere in aktive Form Calcitriol = Steroidhormon (wie Cortison). Supplementation keine Vitamin-, sondern Hormontherapie. Mangel-Irrtum oder Desinformation? Gemessen anhand Serum 25-hydroxyvitamin D [25(OH)D] in ng/ml: >30 ng/ml OK 29-20 ng/ml, Unterversorgung 70 J: 16 ng/ml RDA Höchstbedarf: 1-70 J: 16 ng/ml >70 J: 20 ng/ml Beide Werte gehen von minimal bis keiner Sonnenexposition aus Weit verbreitetes Missverständnis: Höhere RDA/Empfohlene Tägliche Aufnahme = „Grenzwert“ Gesamte Bevölkerung >20 ng/ml für gute Knochengesundheit Realität Mehrheit (etwa 97,5%) braucht

Find out what anxiety is, what is happening in your body & brain and why and how to treat it. If you experience anxiety, this podcast will hopefully help you feel less alone with your symptoms & help you to understand your own body better. Episode 3 resources:Acute Simple Cystitis in Women. UpToDate. Published 2022. Accessed August 29, 2022. Second most common infection in the US proving harder to treat with current antibiotics. Science Daily. Published 2012. Accessed August 29, 2022. Urinary Tract Infections: Causes, Symptoms & Treatment. Cleveland Clinic. Published 2022. Accessed August 26, 2022.Foxman, B. The epidemiology of urinary tract infection. Nat Rev Urol 7, 653–660 (2010). The Link Between UTIs and Sex: Causes and How to Prevent Them. EverydayHealth.com. Published 2022. Accessed August 26, 2022.. 7 Reasons Why Women Get More UTIs Than Men. Virginia Physicians for Women. Published 2022. Accessed August 27, 2022. Genitourinary Problems Worse for Sexually Abused Girls. Medscape. Published 2022. Accessed August 26, 2022.Wiles TJ, Kulesus RR, Mulvey MA. Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp Mol Pathol. 2008;85(1):11-19. Bladder Dysfunction in Sexual Abuse Survivors | Journal of Urology. Journal of Urology. Published 2022. Accessed August 25, 2022.Asselstine M. Body experiences of women survivors of child sexual abuse, implications for therapeutic intervention. Tspace.library.utoronto.ca. Published 1997. Accessed August 29, 2022.Episode 4 resources:Generalized anxiety disorder in adults: epidemiology, pathogenesis, clinical manifestations, course assessment, and diagnosis. Up to Date. Published 2022. Accessed September 5, 2022.Crocq MA. A history of anxiety: from Hippocrates to DSM. Dialogues Clin Neurosci. 2015;17(3):319-325. Furuyashiki T, Narumiya S. Stress responses: the contribution of prostaglandin E(2) and its receptors. Nat Rev Endocrinol. 2011;7(3):163-175. Andreescu C, Lee S. Anxiety Disorders in the Elderly. Adv Exp Med Biol. 2020;1191:561-576. Hoge E, Bickham D, Cantor J. Digital Media, Anxiety, and Depression in Children. Pediatrics. 2017;140(Suppl 2):S76-S80. Tully PJ, Harrison NJ, Cheung P, Cosh S. Anxiety and Cardiovascular Disease Risk: a Review. Curr Cardiol Rep. 2016;18(12):120. Sexual dysfunction & anxiety: Basson R, Gilks T. Women's sexual dysfunction associated with psychiatric disorders and their treatment. Womens Health (Lond). 2018;14:1745506518762664. Mulvey B. Molecular and Functional Sex Differences of Noradrenic Neurons in the Mouse Locus Coeruleus. Cell.com. Published 2022. Accessed September 6, 2022.Facts & Statistics | Anxiety and Depression Association of America, ADAA. Adaa.org. Published 2022. Accessed September 6, 2022.Why Kids and Teens May Face Far More Anxiety These Days. Washington Post. Published 2018. Accessed September 6, 2022.Bickett A, Tapp H. Anxiety and diabetes: Innovative approaches to management in primary care. Exp Biol Med (Maywood). 2016;241(15):1724-1731. doi:10.1177/1535370216657613Bendau A, Petzold MB, Wyka S, Pyrkosch L, Plag J, Ströhle A. Ängste in Zeiten von COVID-19 und anderen Gesundheitskrisen [Anxiety in times of COVID-19 and other health crises]. Nervenarzt. 2021;92(5):417-425. Megan Thee Stallion: Anxiety

A 5-minute summary of a randomized controlled trial comparing the effects of a short-acting vs. long-acting GLP-1 receptor agonist on food intake, appetite and exocrine pancreas function, published in Diabetes, Obesity & Metabolism. Listen for a quick overview of the key findings. Publication: Quast DR, et al. Macronutrient intake, appetite, food preferences and exocrine pancreas function after treatment with short- and long-acting glucagon-like peptide-1 receptor agonists in type 2 diabetes. Diabetes Obes Metab. 2021 Oct;23(10):2344-2353. Additional references: Meier JJ. GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nat Rev Endocrinol. 2012 Dec;8(12):728-42. For more free education, visit the DKIP website, follow us on Twitter (@dkipractice) or connect on LinkedIn. Funding statement: This independent educational activity is supported by an educational grant from Novo Nordisk A/S. The educational content has been developed by Liberum IME in conjunction with an independent steering committee; Novo Nordisk A/S has had no influence on the content of this education.

What is Paget's? Why is it declining across much of the globe? Find out, plus hear an interview with the head of the center for osteoporosis and metabolic bone disease at Cleveland Clinic, Chad Deal, MD. Brought to you by GSK. Intro :11 Today's episode :27 What is Paget's? 1:07 The history of Paget's 5:35 How often is this symptomatic? 9:30 The epidemiology of Paget's 13:22 The data on viruses and Paget's disease 21:08 An interview with Dr. Chad Deal25:09 The numbers are showing a decline in Paget's disease, are you seeing that? 26:03 Identifying Paget's disease … who's picking this up? 27:01 Can you walk us through those studies again? 27:58 Can you tell us a little bit about hypervascularity found in these patients? 30:32 Can you walk us through the history of how the treatments have changed? 31:37 Paget's kind of just doesn't go anywhere … is that what you've seen in your practice? 35:05 What if the patient has poor or borderline kidney function? Do they have other options? 37:07 Have you seen familial cases? Are people more prone to get it if someone in the family has it? 38:32 A discussion on osteosarcoma 39:55 Dr. Deal, thank you so much for your time and your knowledge about metabolic bone 42:46 Episode summary 42:52 I hope you learned something and thanks for listening! 44:47 Disclosure: Brown reports no relevant financial disclosures. Healio was unable to confirm relevant financial disclosures for Deal at the time of publication. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum References: Cundy T. Metabolism. 2018;80:5-14. Haddaway MJ, et al. Br J Radiol. 2007;80:523-526. Poór G, et al. J Bone Miner Res. 2006;21:1545-1549. Renier JC, Audran M. Rev Rhum Engl Ed. 1997;64:35-43. Shaw B, et al. Proc Natl Acad Sci USA. 2019;10463-10472.  Singer FR. Nat Rev Endocrinol. 2015;11:662-671. Wermers RA, et al. J Bone Miner Res. 2008​;23:819-825. Music by Lesfm from Pixabay.

In this episode, Professor Elisabet Stener-Victorin from Karolinska Institute in Stockholm, shares understandings regarding the aetiology of polycystic ovarian syndrome (PCOS) according to the latest research. As a researcher, Elisabet and her team hope to uncover underlying causes of the disease, with the aim of finding better treatments in future. Interestingly, 20 genetic variations have been identified as well as links between androgen exposure in foetal life and epigenetic changes. Tune in to hear more from Professor Stener-Victorin. *Highlights * Potential causes of PCOS (3:00) Insights from Elisabet's research (15:30) How excess androgens in utero impact both genders (23:00) What causes elevated androgen exposure in utero? (30:00) Inflammation – a cause or consequence of PCOS? (37:00) Is the microbiome playing a role in PCOS? (39:30) The influence of electro-acupuncture on PCOS (42:30) Therapeutics on the horizon (52:00) Useful links and resources Professor Elisabet Stener-Victorin - https://staff.ki.se/people/elisabet-stener-victorin Professor Elisabet Stener-Victorin's research group - https://ki.se/en/fyfa/reproductive-endocrinology-and-metabolism-group-page http://ki.se/en/fyfa/reproductive-endocrinology-and-metabolism https://www.monash.edu/medicine/sphpm/mchri/pcos/guideline Recent publications Risal, S., et al. Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome. Nature medicine 25, 1894-1904 (2019). Risal S. , et al. Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders. Transl Psychiatry. 2021 Jan 13;11(1):45. doi: 10.1038/s41398-020-01183-9.PMID: 33441551 Stener-Victorin, E., et al. Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocr Rev (2020). Stener-Victorin, E and Deng, Q. Epigenetic inheritance of polycystic ovary syndrome - challenges and opportunities for treatment Nat Rev Endocrinol. 2021 Jul 7. doi: 10.1038/s41574-021-00517-x. Online ahead of print.PMID: 34234312 Stener-Victorin E, Deng Q. Transmission of Polycystic Ovary Syndrome via Epigenetic Inheritance. Trends Mol Med. 2021 Jun 11:S1471-4914(21)00129-5. doi: 10.1016/j.molmed.2021.05.005. Online ahead of print.PMID: 34127396

Newsletter: https://dralkapatel.com/mailinglist “How can you eat for real change?” Season 7 Episode 3 My guest on this week's episode of The Lifestyle First Podcast is Dr Joanna McMillan Dr Joanna is a TEDx speaker with TEDx MacquarieUniversity with the talk, “Eat for real change.” We discuss the meaning of diet. We highlight the classification of processed foods. We talk about why healthy eating has become so confusing. We reflect on the association and dissociation of diet and weight. We explore how to maintain a long-term relationship with food and reconnect to the joy of eating. 1. The one question we discuss is “How can you eat for real change?” 2. The two references we look at are: 1. Statiscis from Diabtes UK https://www.diabetes.org.uk/professionals/position-statements-reports/statistics 2. Malik, V., Willett, W. & Hu, F. Global obesity: trends, risk factors and policy implications. Nat Rev Endocrinol 9, 13–27 (2013). https://doi.org/10.1038/nrendo.2012.199 https://pubmed.ncbi.nlm.nih.gov/23165161/ 3. The three actions to take are · Eat more whole foods, especially plant foods, minimally processed · Move more – activity and exercise · Sleep well Which of these 3 actionable health tips will you implement? Leave your comments below. -x- Join The Lifestyle First Academy! Take the flagship course – Start Now: Transform your Lifestyle, Transform your Life https://dralkapatel.com/academy/ -x- DISCLAIMER: This content does not constitute or substitute personal one-to-one professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or health care professional with questions about your health. -x- Find Out More/Contact/Follow: Guest: TEDx MacquarieUniversity https://www.youtube.com/watch?v=fbeFn1Xcqo4 Website https://drjoanna.com.au Social https://www.linkedin.com/in/drjoannamcmillan https://www.facebook.com/drjoannamcmillan https://www.instagram.com/drjoannamcmillan Host Newsletter: https://dralkapatel.com/mailinglist Website: https://dralkapatel.com/ Social: https://www.linkedin.com/in/dralkapateluk/ https://www.facebook.com/dralkapateluk https://www.instagram.com/dralkapateluk https://twitter.com/dralkapateluk YouTube: https://www.youtube.com/channel/UCaQrM4ryE0a38zqsednEppQ Podcast: https://anchor.fm/dr-alka-patel --- Send in a voice message: https://anchor.fm/dr-alka-patel/message

Microbiota and muscle highway - two way traffic. Nat Rev Endocrinol. 2020 Feb;16(2):71-72.

References:Matthews E. Acute Kidney Injury and Iodinated Contrast Media. Radiol Technol. 2018;89(5):467CT-77CT.Leung AM, Braverman LE. Consequences of excess iodine. Nat Rev Endocrinol. 2014;10(3):136-42.Koukkou EG, Roupas ND, Markou KB. Effect of excess iodine intake on thyroid on human health. Minerva Med. 2017;108(2):136-46.Patrick L. Iodine: deficiency and therapeutic considerations. Altern Med Rev. 2008;13(2):116-27.Guastamacchia E, Giagulli VA, Licchelli B, Triggiani V. Selenium and Iodine in Autoimmune Thyroiditis. Endocr Metab Immune Disord Drug Targets. 2015;15(4):288-92.Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG. Iodine-Induced hypothyroidism. Thyroid. 2001;11(5):501-10. Zbigniew S. Role of Iodine in Metabolism. Recent Pat Endocr Metab Immune Drug Discov. 2017;10(2):123-6.

Branched-chain amino acids in metabolic signalling and insulin resistance. Nat Rev Endocrinol. 2014 Dec;10(12):723-36

The diabetogenic action of statins - mechanisms and clinical implications. Nat Rev Endocrinol. 2016 Feb;12(2):99-110

Therapy: SGLT2 inhibitor dapagliflozin promotes glucagon secretion in α islet cells. Nat Rev Endocrinol. 2015 Jul;11(7):382