Podcasts about bioworld

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Best podcasts about bioworld

Latest podcast episodes about bioworld

The BioWorld Insider Podcast
The first half of 2024 was strong as M&As and financings dominate

The BioWorld Insider Podcast

Play Episode Listen Later Jul 26, 2024 18:01


Karen Carey, BioWorld managing editor and chief analyst, takes a look at the numbers from the first half of 2024. She finds the first six months to be healthy for the biopharma market while the rest of the year is populated with question marks that include the U.S. presidential election and potential interest rate cuts.

The BioWorld Insider Podcast
Six biopharma executives consider a tough 2023 and are hopeful for a better 2024

The BioWorld Insider Podcast

Play Episode Listen Later Dec 11, 2023 17:05


One aspect of 2023 our group of executives completely agreed on: the past year was tough financially. And they all foresee a more vibrant year ahead for the market. Giving all of them hope were technological breakthroughs such as artificial intelligence, game changing weight loss drugs, the surging fascination with ADCs and hope for lower interest rates. But uncertainty looms about the upcoming general election in the U.S. and ground-shifting gene therapies. In a preview of the annual Biotech Showcase conference, an investor conference for private and micro- to mid-cap biotech companies Jan. 8-10 in San Francisco, BioWorld spoke with Dave Bearss, CEO of Halia Therapeutics Inc., Vimal Mehta, CEO of Bioxcel Therapeutics Inc., Paul Lammers, CEO at Triumvira Immunologics Inc., Chris Pirie, COO of HDT Bio Corp., Thijs Spoor, CEO of Perspective Therapeutics Inc. and Shelley Hartman, CEO of Aegle Therapeutics Corp. They offered insights brought about by years of hard-won experience.

The BioWorld Insider Podcast
AI: driving drug development from effective to remarkable

The BioWorld Insider Podcast

Play Episode Listen Later Sep 6, 2023 26:32


Google's Scott Penberthy joins the podcast for a visionary discussion that scans the horizon for startling changes artificial intelligence will bring to drug development in the relatively near future. Among the gems and eyebrow raisers is talk of dramatic reductions in the time it takes to identify the right molecule for development and how digital clinical trials in the not-too-distant future will substantially shrink study times. This episode also provides a preview of the annual Biofuture conference. Each year, a group of trailblazers, disruptors and forward-thinking executives converge to evaluate and forecast the future of health care. This year, BioWorld is a gold sponsor of the Oct. 4-6 event in New York. If you attend, you'll have the chance to hear panels and join workshops and fireside chats with key opinion leaders like Penberthy.

Feminine Founder
17: Creating Brand Awareness with Rachel Ford Hutman

Feminine Founder

Play Episode Listen Later Aug 29, 2023 19:44


In today's episode, Rachel Ford Hutman and I talk through her journey in media relations, starting Ford Hutman Media and thriving through brand awareness in the life sciences space. Rachel Ford Hutman is the Founder and CEO of Ford Hutman Media. With 15+ years of communications experience at leading global PR agencies and a senior comms role at IBM, she created the agency to provide industry-leading media relations and thought leadership to elite life science companies across the globe. Clients range from venture-backed startups to large cap public companies. Rachel started her career as a reporter and excels at working with the media to bring life science stories to life while still making them accessible to stakeholders.During her career, Rachel has led communications for the world's biggest therapies and medical technologies of all time, including the first RNAi therapy (Alnylam's ONPATTRO), the first technology in the world to personalize insulin 24 hrs. a day (Medtronic's MiniMed 670G), IBM's AI launch into healthcare (Watson Health), the first therapy for DMD (Sarepta's EXONDYS 51), and Google's sister life science company (Verily). She has counseled some of the most well-known health/ technology organizations and developed communications strategies for the world's biggest brands (Verily, Johnson & Johnson, Medtronic, Pfizer, IBM, Best Buy, Takeda, Sanofi, Shire, Brigham & Women's, NHS).Rachel is consistently leveraging her long-standing relationships with global agenda-setting reporters on behalf of clients including CNBC, FOX Business, BBC, AP, Reuters, Bloomberg, The Today Show, Newsweek, Financial Times, Fast Company, TIME, Wired, Forbes, WSJ, NYTs, and key health trades like Modern Healthcare, Becker's Hospital Review, Digital Health Journal, GenomeWeb, BioWorld, Tech Republic, FierceBiotech, Endpoints, Drug Discovery Today and many more. Rachel also has investor and analyst relations experience that adds to her ability to highlight market dynamics.Named a Power Woman of San Diego 2020 and PRSA's PR Professional of the Year in 2011, Rachel has built a reputation for her positive energy, creativity and humor. She received her MA in communications and media studies at San Diego State University and her BA in English/ History from University of Maryland, Baltimore County. Rachel has presented on communications strategy to PR News, PR Week, The International PR Research Conference, NC State and San Diego State University. You can find Rachel HERE More on Ford Hutman Media HERE Subscribe HERE for exclusive access and bonus episodes!This is an episode that you do not want to miss!Also, if you haven't already done so already, follow the podcast on LinkedIn HERE.  I'm adding a bunch of bonus episodes to the feed and, if you're not following, there's a good chance you'll miss out.Join 1K+ women receiving  my weekly newsletter where I help YOU level up your recruiting skills, share market insights also with all the tips on how to recruit your next Rockstar HERE Thanks for listening! Support the show

The BioWorld Insider Podcast
The struggle is real: The first half of 2023 was an uphill climb

The BioWorld Insider Podcast

Play Episode Listen Later Aug 16, 2023 25:47


Guests Karen Carey, BioWorld's managing editor, and Mike Ward, Clarivate's global head of Life Sciences and Healthcare Thought Leadership, discuss the deals, financing and M&A landscape for the first half of 2023 and how U.K. biopharmas are faring post Brexit.

The BioWorld Insider Podcast
Better times ahead for the biopharma sector? Could be, the new numbers say

The BioWorld Insider Podcast

Play Episode Listen Later Apr 24, 2023 28:02


It used to be a lot easier to find partners. After two years of strong dealmaking, the volume and value of partnerships slid in the first quarter of 2023. M&As also are down compared to prior years. But there are some reasons to be cheerful. Looking at first quarter numbers and surveying the big picture on this BioWorld Insider podcast are Karen Carey, BioWorld's managing editor and senior data analyst, along with Tim Shannon, a general partner at Canaan. Carey just wrote about biopharma deals and completed M&As in the first quarter. Shannon, who's been with Canaan since 2009, has a new fund sporting $850 million in new capital, including an oversubscribed $650 million fund for seed and series A financings. They both offer their insights into the first quarter's numbers and what may lie ahead. Hosted on Acast. See acast.com/privacy for more information.

The BioWorld Insider Podcast
Radiopharmaceuticals: The next big disrupter?

The BioWorld Insider Podcast

Play Episode Listen Later Apr 5, 2023 13:58


It all goes to show how a good idea can't be kept down. Madam Curie started radiopharmaceuticals in the late 1800s and now it's a multibillion-dollar industry. BioWorld's seven-part series on a new era of radiopharmaceuticals reveals their increasing importance as part of cancer treatments because they have fewer side effects and cause far less damage to tissue than previously. The big idea is taking the hallmarks of two cancer therapies – radiology and chemotherapy – and merging them. That's what makes this evolving technology a disrupter. The series, led by BioWorld Staff Writer Tamra Sami, takes a close look at the different radiopharmaceutical moieties and the science behind them, the supply chain vulnerabilities, the regulatory landscape, the patient journey and therapies in the pipeline. Sami summarizes this special report in the latest edition of the BioWorld Insider Podcast. Hosted on Acast. See acast.com/privacy for more information.

Live Long and Master Aging
Anette Breindl: Is life extension a pipe dream?

Live Long and Master Aging

Play Episode Listen Later Nov 2, 2022 27:31 Transcription Available


Extending lifespan is the goal of many in the field of human longevity, with myriad companies developing pharmaceuticals to target the key biological markers of aging. But which interventions actually work? A team of researchers at BioWorld  recently delved into the latest science to try to make sense of the many clinal trials focused on the biology of aging. Anette Breindl is a co-author of the magazine's special report on aging, which also explores whether the large sums of money going into aging research are leading to real-world breakthroughs. In this LLAMA podcast interview Anette discusses her pragmatic approach to anti-aging and why life extension could still be a pipe dream - at least in our lifetimes. Read the BioWorld report:  Extending the human lifespanDISCOUNTS▸ Recharge Health is offering LLAMA listeners a $30.00 discount on the purchase of FlexBeam, for red light therapy, which may help your body heal and promote  the health of skin and muscle tissue .  Use the code LLAMA at checkout. This is in addition to a 25% summer sale discount being offered by Recharge Health. ▸ Time-line is offering LLAMA podcast listeners a 5% discount on its Mitopure products - Mitopure Powder, Softgels and Mitopure + Protein. Mitopure supports improvements in mitochondrial function and muscle strength. Use the code LLAMA at checkout▸ DoNotAge is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. Use the use code LLAMA for purchases at DoNotAge.orgHealth queries can be answered by emailing: hello@donotage.orgHealthy Lifestyle Solutions with Maya AcostaAre you ready to upgrade your health to a new level and do so by learning from experts...Listen on: Apple Podcasts SpotifyAffiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout. This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The BioWorld Insider Podcast
Psychedelic evolution: Mindset Pharma looks to change mental health treatment

The BioWorld Insider Podcast

Play Episode Listen Later Sep 21, 2022 25:44


An analyst recently observed that mental health treatments are stuck where cancer was 50 years ago. However, there have been major advancements in developing psychedelic medicines to address that problem. BioWorld staff writer Lee Landenberger talked with James Lanthier, the CEO of Mindset Pharma, which is developing what it calls “next-generation” psychedelic medicines to treat neurological and psychiatric disorders. Lanthier discussed challenges facing companies developing psychedelic treatments and how to overcome the one-size-fits-all, trial-and-error approach to mental health treatment that often seems stuck in the past. Hosted on Acast. See acast.com/privacy for more information.

The BioWorld Insider Podcast
$1B+ biopharma deals keep values afloat, even amid muted volume

The BioWorld Insider Podcast

Play Episode Listen Later Sep 8, 2022 28:16


BioWorld writers bring you the details of new R&D alliances, financings, IPOs and M&A every day. These stories are the heartbeat of the relationships between industry giants and their smaller, more innovative peers. But what's the top-line read for dealmaking these days? With nearly 1,000 biopharma deals completed through early August amid a volatile economic climate, there's a lot to talk about. Join the BioWorld Insider podcast as we talk with Senior Analyst Karen Carey, whose data-driven research delivers a detailed picture of the ups and downs. For starters, the sector has seen sharp declines this year in stocks and less money being raised. “What we are seeing seems to be a correction of the intense enthusiasm – the zeal for biopharma during 2020 and 2021 when nobody knew what was going on with COVID,” Carey said. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

The BioWorld Insider Podcast
Extending the human lifespan

The BioWorld Insider Podcast

Play Episode Listen Later Jul 18, 2022 41:38


In Extending the human lifespan, a BioWorld special report, the team examined the latest science, the key biological drivers that can be targeted pharmacologically and the companies developing potential “Fountain of Youth” candidate drugs. In this episode of the BioWorld Insider Podcast, the team discussed the report's highlights and key takeaways. In what could be a holy grail for humanity, anti-aging drugs would simultaneously reduce the risk of multiple age-related illnesses in one. BioWorld found that investments in life-extending drugs and the number of clinical trials are on the rise. Can we hopscotch over the many diseases of aging? The impact could be staggering. Equitable access to drugs and therapies tackling aging could reduce health care costs in a major way and improve quality of life. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Who advises the CDC on big COVID decisions and how's that working out?

The BioWorld Insider Podcast

Play Episode Listen Later Feb 23, 2022 24:23


The CDC's Advisory Committee on Immunization Practices (ACIP) always had a full schedule, but COVID-19 amped it up tremendously. Some public health policy observers wonder whether the increased responsibility meets the CDC's needs and if the CDC pays enough attention to the committee. William Schaffner, professor of preventive medicine in the Department of Health Policy as well as professor of medicine in the Division of Infectious Diseases at the Vanderbilt University School of Medicine, joined ACIP in 1982. He has deep insight on how the committee works as the National Foundation for Infectious Diseases' liaison to ACIP. He joined BioWorld staff writer Lee Landenberger to talk about the committee and how it makes the big decisions that ultimately affect public health policy. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Long COVID: Potentially the next public health crisis

The BioWorld Insider Podcast

Play Episode Listen Later Feb 14, 2022 23:42


With the study of long COVID-19 continuing to evolve, the BioWorld team is taking a closer look at the condition -- a complex syndrome affecting more than 100 million people globally -- and what's being done about it. In this episode, BioWorld Senior Science Editor Anette Breindl and Staff Writer Lee Landenberger, fresh off writing a pair of detailed stories about these issues, join us to talk about how consensus around what long COVID is has emerged. Why is that consensus important and what sort of treatments are in the pipeline? Are patients moving closer to the center of the conversation as we continue to navigate this pandemic, which the World Health Organization reminded us recently is very much not yet over? Listen to find out! See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Another record year for biopharma financings bodes well for 2022

The BioWorld Insider Podcast

Play Episode Listen Later Dec 9, 2021 18:40


In another record year for biopharma fundraisings, more money than ever pulsed through the industry. The volume and value of pharma IPOs and venture capital financings are at their highest levels. Private financings for 2021 easily outdistanced those from 2020, much of it powered by SPACs. Where is it all going in 2022? Two experts joined BioWorld to share their thoughts. Kleanthis Xanthopoulos is a co-founder and executive chairman of Shoreline Biosciences. For more than 20 years he's been an executive, company founder, CEO, investor and board member in biopharma research. Also joining the discussion was Joe Hernandez, CEO and executive chairman of Blue Water Vaccines, who founded or led eight health care and pharmaceuticals companies. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Aduhelm's hard lessons and what it means for other Alzheimer's drugs

The BioWorld Insider Podcast

Play Episode Listen Later Dec 9, 2021 32:29


The FDA's June 2021 approval of Aduhelm (aducanumab), the first plaque-targeting therapy, rattled the company, regulators and the market. BioWorld brought together two experts to get their thoughts as each is involved in developing vaccines or treatments for Alzheimer's or Parkinson's disease. Michael Agadjanyan is the president of Nuravax Inc., which is developing antibodies for preventing Alzheimer's and Parkinson's disease. We also spoke with Robert Glanzman, who is chief medical officer of Clene Nanomedicine Inc., which is developing a nanotherapeutic for Parkinson's disease. Both have strong views on Aduhelm. They also had a spirited debate on the science of curing dementia. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Reality check: How did industry develop COVID-19 vaccines and drugs so fast?

The BioWorld Insider Podcast

Play Episode Listen Later Oct 26, 2021 16:37


The COVID-19 pandemic is so all encompassing and complex, with dramatic details shifting almost hourly, that it can be easy to lose track of the big picture. And there are so many questions. Has industry pushed out vaccines too fast? Was there adequate testing? Did they take shortcuts? Why were governments pushing for boosters before the scientific data was available? We asked BioWorld's regulatory editor Mari Serebrov, who has covered the pandemic since the beginning, to help put it all into perspective. She has strong insights into vaccine development, including the handful of winners and quite a few failures in the more than 1,000 vaccines and therapeutics in the pipeline. Listen to the discussion on how industry has pushed out vaccines and drugs in this turbo-charged timeline. See acast.com/privacy for privacy and opt-out information.

The Licensing Mixtape
S3 E7: Bioworld Presents... Cultivating Happiness

The Licensing Mixtape

Play Episode Listen Later Sep 13, 2021 18:41


Jennifer Staley and Beth Taylor of Bioworld share what keeps the team positive and optimistic—and why it's so important for licensing success.

Blind Politics with Dr. A.J. Nolte
A Deep Dive into the Delta Variant with Mari Serebrov: 9/1/21

Blind Politics with Dr. A.J. Nolte

Play Episode Listen Later Sep 1, 2021 40:38


Our guest, Mari Serebrov, has been tracking COVID since day one through her work as a regulatory editor with BioWorld. In this episode, she talks with Dr. Nolte about the impact of the delta variant and the means we have to fight against it.

The BioWorld Insider Podcast
As biopharma deals keep pace, M&A volumes languish

The BioWorld Insider Podcast

Play Episode Listen Later Jul 9, 2021 14:19


Biopharma deal-making activity, a closely-watched marker of industry health, remained alive and well in Q2. But whither M&A? And what's with all those $1 billion-plus deals? Join News Editor Michael Fitzhugh and BioWorld Senior Analyst Karen Carey as they chat about the latest currents in combinations, partnerships amid the pandemic, and the rising values of up-front payments – at least for those clinical-stage companies lucky enough to make lucrative deals ahead of commercialization. BioWorld subscribers looking for an even deeper dive on the numbers can read Karen's Q2 Deals and M&A overview, including overviews M&A value and volume by year, a list of the year's top M&A deals to date – led by Jazz Pharmaceuticals plc's takeout of GW Pharmaceuticals plc – and even more details about the world of biopharma deals in BioWorld Snapshots. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Finally, a new medicine for Alzheimer's disease

The BioWorld Insider Podcast

Play Episode Listen Later Jun 10, 2021 9:14


The FDA's accelerated approval of Biogen Inc.'s Alzheimer's disease therapy, Aduhelm (aducanumab), is the first real beacon of hope in 18 years for the 50 million people living with the disease. But the approval was met with controversy over the drug's efficacy and pricing. Even as Biogen readies to launch in just two weeks with more than 900 sites lined up to start treating patients, a required confirmatory study could sink everything.BioWorld has been reporting on the development of Aduhelm since its discovery, by way of Neurimmune AG's reverse translational medicine technology. Later licensed to Biogen, it was co-developed with Eisai Co. Ltd.In this episode, News Editor Michael Fitzhugh talks with Ivana Rubino, Biogen's VP of global and U.S. medical affairs for Alzheimer's disease, about the approval, the controversies and what it all means for Biogen's future. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
The BioWorld Insider Podcast - trailer

The BioWorld Insider Podcast

Play Episode Listen Later Jun 4, 2021 0:33


Breakthrough medicines, billion-dollar deals, spectacular clinical successes and crushing failures all play a part in biopharma's dynamic story. Developers make scientific advancements with the potential to change everything, only to face regulatory conundrums and ever-fluctuating markets. The BioWorld Insider podcast lets you hear directly from the movers and shakers whose collective work is changing how we all live. Join us each week for a new conversation. See acast.com/privacy for privacy and opt-out information.

The BioWorld Insider Podcast
Introducing the BioWorld Insider Podcast

The BioWorld Insider Podcast

Play Episode Listen Later Jun 4, 2021 0:33


insider bioworld
The Licensing Mixtape
License Global x Bioworld - Episode 2: Connecting Fans at Retail

The Licensing Mixtape

Play Episode Listen Later May 17, 2021 24:52


Navigating the consumer engagement landscape is more challenging than ever. With new platforms emerging every day, consumers have options on where to engage. Bioworld understands that and is meeting the fans wherever they are. This makes it easier for their retail and brand partners to succeed. McKenna Morgan, digital editor, License Global is joined by Beth Taylor, Jennifer Staley, Sean Parnell, Chad Neurenberg and Casey Hulse of the Bioworld team to discuss how Bioworld connects with fans at retail.

The Licensing Mixtape
License Global x Bioworld - Episode 1 - Powering Fandom

The Licensing Mixtape

Play Episode Listen Later Feb 22, 2021 26:02


Bioworld's Jennifer Staley and Beth Taylor join License Global's Bibi Wardak and McKenna Morgan for an in-depth discussion on fandom, the creativity it fuels and how Bioworld has become a fan-favourite from gaming to movies, anime and beyond.

The Licensing Mixtape
S1 E9: Bioworld's Fan First Approach to Licensing

The Licensing Mixtape

Play Episode Listen Later Oct 5, 2020 28:24


Bioworld Merchandising's Jennifer Staley and Beth Taylor highlight how the company's “Fandom Forever” approach has redefined the licensing business in this special Festival of Licensing episode.

iSmart Podcast
The art of telling the story with Rachel Ford Hutman, Founder and CEO of Ford Hutman Media

iSmart Podcast

Play Episode Listen Later Sep 22, 2020 28:28


Rachel is a global health industry connector and creative problem solver. She has worked on some of the world's biggest therapies and medical technologies of all time, including the first RNAi therapy (Alnylam's ONPATTRO), the first therapy for DMD (Sarepta's EXONDYS 51), the first technology in the world to personalize insulin 24 hrs. a day (Medtronic's MiniMed 670G), IBM's AI launch into healthcare (Watson Health) and Google's sister life science company (Verily). She has counseled some of the most well-known health/ technology organizations and developed communications strategies for the world's biggest brands (Google, Johnson & Johnson, Medtronic, Pfizer, IBM, Best Buy, Takeda, Sanofi, Shire, Brigham & Women's, NHS), but she is most proud of her work telling patient stories. Rachel excels at working with the media to bring health stories to life while making them accessible to stakeholders. With 15-years of communications experience, she is consistently leveraging her long-standing relationships with global agenda-setting reporters across a range of outlets from CNBC, BBC, AP, Reuters, Bloomberg, The Today Show, Newsweek, Financial Times, Fast Company, TIME, Wired, Forbes, WSJ, NYTs, and key health trades like Modern Healthcare, Becker's Hospital Review, Digital Health Journal, GenomeWeb, BioWorld, Drug Discovery Today and many more. Rachel also has investor and analyst relations experience that adds to her ability to highlight market dynamics. She was named a Power Woman of San Diego 2020 and selected PRSA's PR Professional of the Year in 2011 for her published research on stakeholder engagement. Rachel has built a reputation for her energy, creativity and humor. She received her MA in communications and media studies at SDSU and her BA in English at UMBC.  Support this podcast

IDEA Collider
IDEA Collider | Daphne Zohar

IDEA Collider

Play Episode Listen Later Aug 6, 2020 45:52


PureTech Health is an advanced, clinical-stage biopharmaceutical company developing novel medicines targeting serious diseases that result from dysfunctions in the nervous, immune, and gastrointestinal systems (brain-immune-gut or the “BIG” axis), which together represent the adaptive human systems. PureTech Health is at the forefront of understanding and addressing the biological processes and crosstalk associated with the BIG axis. By harnessing this emerging field of human biology, the Company is pioneering new categories of medicine with the potential to have great impact on people with serious diseases. PureTech Health is advancing a rich pipeline that includes multiple post human proof-of-concept studies and pivotal stage programs. PureTech’s rich research and development pipeline has been advanced in collaboration with some of the world’s leading scientific experts, who along with PureTech’s team of biopharma pioneers, entrepreneurs and seasoned Board, identify, invent, and clinically de-risk new medicines. With this experienced team pursuing cutting edge science, PureTech Health is building the biopharma company of the future focused on improving and extending the lives of people with serious disease. Ms. Zohar created PureTech Health, assembling a leading team to help implement her vision for the Company. Ms. Zohar has been recognized as a top leader and innovator in biotechnology by a number of sources, including EY, BioWorld, MIT’s Technology Review, the Boston Globe, and Scientific American. She sits on the Technology Development Fund Advisory Board at Children’s Hospital Boston, is an Editorial Advisor to Xconomy, and is on the Board of Advisors of Life Science Care 

First Author Conversations
Delivering neoantigen peptides with nanoparticles, Geoffrey M. Lynn, Ph.D., Avidea Technologies

First Author Conversations

Play Episode Listen Later Feb 11, 2020 27:29


In this episode, Dr. Geoffrey Lynn talks about the development of a polymer-based antigen delivery technology- SNAP, or self-assembling nanoparticles, displaying a patient’s own neoantigens to induce a CD8 T-cell response and tumor regression in animal models. The work was published on Nature Biotechnology on Jan. 13th 2020, “Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens”.Geoff first introduced personalized cancer vaccines. He then explained how one class of therapies- checkpoint inhibitors unleashes the immune system to attack cancer.“Now the reason why precision medicine or personalized therapy is important is because… each cancer is going to have a unique set of mutations…, if we want to leverage the immune system, we may have to target a unique set of cancer antigens or these mutations which are often referred to as neoantigens”.By sequencing DNA and RNAs from a tumor, as well as using bioinformatics methods, one can identify predicted peptide neoantigens, and create a patient specific vaccine.We discussed the different delivery vehicles for personalized cancer vaccines. “When you have a peptide antigen, that's exactly what you want to display to the immune system. So there's no concern that if you have a DNA, RNA expression system or virus that your antigen won't be expressed in vivo… They [peptide antigens] are a very modular platform.”Geoff further explained how his team was able to stimulate a stronger immune response by combing peptide antigens with specific adjuvants, Toll-like receptor 7/8 agonist.The final challenge they tackled in this work is the amino acid sequence variability and physical/chemical heterogeneity of peptide neoantigens. This is why SNAP technology is developed and where SNAP comes in handy. SNAP links neoantigens to a polymer that self-assemble into the same particle size, the same amounts of peptide antigen in each particle, and the same overall charge of the particle. Geoff specifically acknowledged GenScript’s support in building thousands of peptides for them to evaluate and develop SNAP technology, especially “peptide antigens that are very rare, are the most hydrophobic, the most charged, and the most hydrophilic”, Geoff said, “this allowed us to really prove the versatility of the technology; so that was quite critical to really convincing us as well as potential funders, that we've really addressed this issue of allowing for consistent formulations with any peptide antigen.”Dr. Lynn is the CEO of Avidea Technologies. This publication is also highlighted in a BioWorld article, “Standardized delivery of unique neoantigens improves T-cell vaccines”.

MuggleCast: the Harry Potter podcast
#444: Harry Potter Gift Guide Extravaganza 2019

MuggleCast: the Harry Potter podcast

Play Episode Listen Later Nov 25, 2019 78:57


The Potter Collector (http://www.youtube.com/thepottercollector) joins us for MuggleCast’s Harry Potter Gift Guide! Harry Potter: The Exhibition is now open in Lisbon, Portugal! Harry Potter Holiday Gift Guide: What were some of the biggest items to debut in 2019? The Potter Collector talks Nimbus 2000, Mystery Wands from Walmart (https://www.walmart.com/ip/Noble-Collections-Harry-Potter-Mystery-Wand/105076249) and OutofPrint.com (https://outofprint.com/) Andrew: Hallmark has official Harry Potter ornaments (Hogwarts Castle Tree Topper (https://www.hallmark.com/ornaments/keepsake-ornaments/harry-potter-collection-hogwarts-castle-musical-tree-topper-with-light-1QXI3277.html) ) as well as a Golden Snitch Coffee Mug (https://www.hallmark.com/gifts/kitchen/mugs-and-teacups/harry-potter-golden-snitch-coffee-mug-20-oz.-1HPO1007.html) and Gringotts Vault Piggy Bank (https://www.hallmark.com/gifts/home-decor/decorative-accessories/harry-potter-gringotts-vault-bank-6003759.html) Eric: LEGO is always a safe bet for any Potter fan (Hogwarts Full Set (https://www.lego.com/en-us/product/hogwarts-castle-71043) , Hogwarts Express (https://www.lego.com/en-us/product/hogwarts-express-75955) and Grindewald’s Escape (https://www.lego.com/en-us/product/grindelwald-s-escape-75951) ) and so are PUZZLES from the New York Puzzle Company (https://www.newyorkpuzzlecompany.com/collections/harry-potter) ! Micah: The Noble Collection has some great adult Potter items (Fawkes (https://www.noblecollection.com/Item--i-STA-HP-7200) , Basilisk Book End (https://www.noblecollection.com/Item--i-BOK-HP-7148) and Fluffy (https://www.noblecollection.com/Item--i-STA-HP-7954) ) Laura:  Alex and Ani’s Harry Potter inspired jewelry (https://www.alexandani.com/time-turner-spinner.html?gclid=CjwKCAiAzuPuBRAIEiwAkkmOSMC2_mkRVVBSvQCM1fzV0xUTU62HCv_XwXuq8_yyFrriBK_GDBzlJBoCPu4QAvD_BwE) , Bioworld’s 9 & 3/4 purse (https://www.amazon.com/Harry-Potter-Deluxe-Handbag-Satchel/dp/B074WHX96D/ref=mp_s_a_1_2_sspa?keywords=harry+potter+purse&qid=1574578986&sr=8-2-spons&psc=1&spLa=ZW5jcnlwdGVkUXVhbGlmaWVyPUExUTYzUDYxTVNNNEc4JmVuY3J5cHRlZElkPUEwMzA0Njk5M0Q2WjE3T09RVzZITyZlbmNyeXB0ZWRBZElkPUEwNjQ3OTg2M0tUSVNPUFpSOUxKNyZ3aWRnZXROYW1lPXNwX3Bob25lX3NlYXJjaF9hdGYmYWN0aW9uPWNsaWNrUmVkaXJlY3QmZG9Ob3RMb2dDbGljaz10cnVl) and the Harry Potter Christmas in the Wizarding World Advent Calendar (https://www.merchoid.com/harry-potter-christmas-in-the-wizarding-world-advent-calendar/) The Potter Collector’s favorites include: the 20th Anniversary Brian Selznick Editions, the 20th Anniversary UK editions, Nimbus 2000 by Cinereplicas (https://cinereplicas.com/products/harry-potter-nimbus-2000-broom-2019-edition) , Subscription Boxes (GeekGear (https://geekgearbox.co.uk/) , Wizarding Trunk (http://www.thewizardingtrunk.com/) , Bibbidi Bobbidi Boxes (https://bibbidiboxes.com/) ) and OutofPrint.com Shirts Andrew recommends checking out BoxLunch.com (https://www.boxlunch.com/homepage) for the adult Harry Potter fan in your life! Pottery Barn has you covered around the house! Check out the Mirror of Erised (https://bit.ly/2OCAjoF) and this really cool floating candle (https://bit.ly/2riSLdS) ! Codenames (https://www.amazon.com/USAopoly-Harry-Potter-Codenames-Movies/dp/B07CJSWQBN) , Potter-themed playing cards (https://www.amazon.com/dp/B078W7R6KK/ref=cm_sw_r_cp_api_i_dBA2Db5M180DK) , Harry Potter Munchkin (https://www.amazon.com/USAopoly-Munchkin-Deluxe-Harry-Potter/dp/B07CJZYSNV) and Cards Against Muggles (https://www.amazon.com/Box-Against-Potte-300-Cards/dp/B07QG9M97Z/ref=sr_1_4?keywords=cards+against+muggles&qid=1574622429&s=toys-and-games&sr=1-4) guarantee a fun night with friends! Patrons weigh in with their gift ideas, including advent calendars (FUNKO (https://www.hottopic.com/product/funko-harry-potter-pocket-pop-2019-advent-calendar/11944102.html?fbclid=IwAR1Jg7LSJ_S3aTU_4-upl_cfIzwmE1Tfc6zoLq47iqddtOh5BYcUR7fc8Ps) , LEGO (https://www.amazon.com/dp/B07NRSY3RW/ref=cm_sw_r_other_apa_i_Xtl1DbEG52FNG?fbclid=IwAR3VMUDAhQh2b1ulgDQuD8JjVkNAic57gBit9ZOKMx3WZdDNmd7omxk6zGw) and sock (https://www.target.com/p/women-39-s-harry-potter-castle-15-days-of-socks-advent-calendar-assorted-colors-one-size/-/A-54651521?fbclid=IwAR3Ui0Yaajk2ZPYw7jvvd-kyTlrICQRZS5K40a_TksUC3YQHfKsjZEAx-Cc) ), J.K. Rowling Boss The Bestseller List Like (https://www.crateandbarrel.com/j.-k.-rowling-boss-the-bestseller-list-like/s417313?st=jk%20rowling&fbclid=IwAR08DPW2kkaewNOj1KqLLMR64JBhGIM4uNsbHJoT3DyMnm01qotv7eGdS90#modal) , Harry Potter Spirit Jerseys (https://www.boxlunch.com/search?q=harry+potter+spirit+jersey) , Commissioned Art From Sydney Dean (https://www.etsy.com/shop/sydsketch) and a Christmas in The Great Hall Candle (https://www.frostbeardstudio.com/products/christmas-in-the-great-hall?fbclid=IwAR0m25rpEfBtStFow2nJgx56cxAHJ5LIaNhDOJ2PYglYOZ_ECT0m3Gmq5gE) We cover some of the classic Potter gifts: books, movies video games and more! Our Top 10 Holiday Potter Gifts! Quizzitch: What does Neville get for his 15th birthday? Join our community at Patreon.com/MuggleCast (http://www.patreon.com/MuggleCast) and receive magical benefits, including early access to the show via our live streams! This week, we have a very special edition of the Dueling Club where Potter holiday gift items square off against each other!

My Little Pony Talk
MLP G4 Plushies PT 4 Baby Boom,BBR,Bioworld - 4/23/2018

My Little Pony Talk

Play Episode Listen Later Apr 23, 2018 148:00


They are soft and cuddly.  Oh yes, we have made it to Plushies.  Now Hasbro has basically given license to several different companies to create these creations, so we will be going through them by company.  Please note that if there are less than 5 plushies in the company’s selection we will lump them with other companies.  Also, if there are more than what we can do in one show we will of course be dividing them up as well.  The Blind Bag Pony of the Week: Wave 13 - Ribbon Heart The website we will be using is: MLP Merch http://data.mlpmerch.com/ Also, this is the checklist of pony's we have done already, please note this will be updating as we go along. http://data.mlpmerch.com/checklist/921/ If any of our listeners know of a good website to use please contact us at mylittleponytalk@gmail.com please when contacting us with a website make sure it is a site that is always kept up to date. Also, join us for our wacky conversations. Please note that since there are very few items in the G4 line we do have a lot of random talk at the start of the show.  For example, pony mail, or even non-pony related packages as the contents are never known till they are opened. Then some random news, do apologize if we do more than intended but this is also to catch ourselves up with each other.

Jedi News: A Star Wars Podcast Network
Galactic Fashion: Episode 28

Jedi News: A Star Wars Podcast Network

Play Episode Listen Later Sep 27, 2017 62:08


Galactic Fashion is a monthly podcast dedicated to Star Wars and geek fashion, hosted by Johnamarie Macias and Teresa Delgado and part of the Jedi News Network. In episode 28, the two ladies talk about the Force Friday products released by Her Universe, Bioworld, ThinkGeek, and Loungefly. They also bring you the latest updates from Po-Zu, UtinniBikini, and Elhoffer Design as well as discuss the new collections from Jamberry and Cargo Cosmetics. For this month's episode, Johnamarie and Teresa had planned to interview Mari R. Cole (@TweetedFromMars, @sentfrommars), but since she recently went into labor, we send her warm and thoughtful wishes. Instead of an interview, Teresa and Johnamarie bring back "Rate the Look," where they grade six character outfits from Disney's Descendants 2. Bonus: Make sure to stay until the very end for some hilarious bloopers. Lastly, make sure to visit Galactic Fashion at @galacticfashionpod on Instagram to find a gallery of photos pertaining to the brands and releases mentioned in this episode.

Jedi News: A Star Wars Podcast Network
Galactic Fashion: Episode 24

Jedi News: A Star Wars Podcast Network

Play Episode Listen Later May 31, 2017 121:03


Galactic Fashion is a monthly podcast dedicated to Star Wars and geek fashion, hosted by Johnamarie Macias and Teresa Delgado and part of the Jedi News Network. In episode 24, the two hosts talk about the latest releases from Her Universe, the upcoming Hoth collection from Bioworld, the Harry Potter inspired fitness line from Castle Corsetry, and much more! Johnamarie and Teresa also interview (22:50) the winners of the Her Universe Fashion Show 2016: Hannah Kent (@pixel_stitcher), Camille Falciola (@frakkinfrocks), and Jesse Thaxton (@amayademorte). They talk about the Wonder Woman fashion collection from Her Universe and Hot Topic, their experiences at the Her Universe Fashion Show, and their thoughts on geek fashion. Make sure to visit Galactic Fashion at @galacticfashiontwg on Instagram to find a small collection of photos pertaining to the brands and releases mentioned in this episode. You can listen to episode 24 here on iTunes and email us at Twg.galacticfashion@gmail.com with your comments, views and opinions to be a part of the show.

Entertainment Earth Podcast
Entertainment Earth Video Game Podcast: May 26, 2017

Entertainment Earth Podcast

Play Episode Listen Later May 26, 2017


Amazing new Zelda offerings from Bioworld. New downloads. Castlevania gets animated. Direct link: http://www.entertainmentearth.com/podcasts/170526b.mp3

Jedi News: A Star Wars Podcast Network
Galactic Fashion: Episode 20

Jedi News: A Star Wars Podcast Network

Play Episode Listen Later Jan 18, 2017 65:01


Galactic Fashion is a monthly podcast dedicated to Star Wars and geek fashion, hosted by Johnamarie Macias and Teresa Delgado and part of the Jedi News Network. In episode 20, the two hosts talk about Her Universe updates, new Star Wars handbags from Bioworld, the latest from Kay Jewelers, and the teasers from Po-Zu's Star Wars footwear collection! Plus, they interview (13:55) the latest member of Team Jedi News. Her name is Joelle (Instagram: @Joelle), a London girl who loves Star Wars, incorporates a Stormtrooper belt with her everyday clothes, and who’s a Young Person's Ambassador for Alopecia UK. You

Woman Up! Podcast
Woman Up! Podcast #39 - 2016 Holiday Gift Guide

Woman Up! Podcast

Play Episode Listen Later Dec 8, 2016 40:00


Gift Guide Time! OhCatrina, MisfitsTamara & SarahTheRebel talk Capcom Cup, PlayStation Experience, the new Guardians of the Galaxy 2 trailer and our picks for geeky gifts! Chick Picks:- Go follow https://twitter.com/HelloKittyRicki- The Walker Papers series - first book called Urban Shaman by C.E. Murphy - half Native American/Irish female protagonist- Please support Standing Rock http://www.commondreams.org/views/201... GIFT GUIDEGeneral Tips:- ThinkGeek for nerdy home goods- Video game official stores (BioWare, Capcom, 2K etc)- Loot Crate for mystery subscriptions- Game bundles- Amazon- Homemade- Etsy Catrina's Picks: - In-game gifts- DC’s Young Animal Comics (Mother Panic, Shade the Changing Girl) http://amzn.to/2ghfyic- Netflix Subscription! With recommendations- Phone photography add-ons (lenses, etc) http://amzn.to/2henYZF- Going fancy? Musterbrand’s Rogue One jackets https://us.musterbrand.com/collection... Sarah's Picks:- Start them off on a comic series: Saga Volume 1, WicDiv or Rat Queens! http://amzn.to/2g6t2Pw- Bluray: Star Trek Beyond or Captain America: Civil War http://amzn.to/2g6tzB5- ThinkGeek Portal Aperture Sports Bra and work out shorts http://www.thinkgeek.com/product/jihi/- Geeky Holiday Sweater (examples: http://www.hottopic.com/her-universe)- Elhoffer Design now has gift cards! https://elhofferdesign.com/products/g... Tamara's Picks:- DC Comics Converse https://www.journeys.com/product/407095- Wonder Woman tiara ring https://www.etsy.com/listing/25313684...- TNG Uniform Hoodie - http://www.thinkgeek.com/product/118a...- Spider-Gwen purse by Bioworld http://www.fun.com/marvel-spider-gwen...- Fancy Dice sets http://amzn.to/2g6snO8 Prefer to listen to WUP? http://Allgames.com/WUP or http://bit.ly/WUPiTunes Twitter: http://twitter.com/WomanUpShow SarahTheRebel, MisfitsTamara and ohCatrina join forces to form Woman Up! Podcast the gaming, comics and all things geeky podcast run by crazy cat ladies. Personal Twitters:@SarahTheRebel@MisfitsTamara@ohcatrina Watch Woman Up! live once a month on www.twitch.tv/sarahtherebel

Jedi News: A Star Wars Podcast Network
Galactic Fashion: Episode 16

Jedi News: A Star Wars Podcast Network

Play Episode Listen Later Sep 29, 2016 89:54


Galactic Fashion is a monthly podcast dedicated to Star Wars and geek fashion, hosted by Johnamarie Macias and Teresa Delgado and part of the Jedi News Network. In episode 16, the two hosts discuss the production issue associated with the Her Universe x Hot Topic Rey Dress, upcoming Rogue One collections from Her Universe, Merchoid, EMP, Bioworld, and Cufflinks.com, the new jewelry collection by Justin Davis, and much more! Plus, a geek fashion interview with Kay (@Geek_Kay), a FANgirl Blog contributor who covers a variety of topics, including geek fashion. You can contact us on Skype at JediNewsNetwork with your comments, views and opinions and be a part of the show.