Concept of extending human lifespan by improvements in medicine or biotechnology
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Aging is not something Zoltan Istvan plans to accept quietly. He wants to treat death like a technical bug, rewrite the rules of biology, and turn California into the global test bed for radical human upgrades. From cyborg implants to AI driven longevity science, this episode explores what happens when a candidate for governor openly argues that humans should evolve beyond their biological limits and take control of how long and how well they live. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Zoltan Istvan, a leading transhumanist, futurist, longevity advocate, and current candidate for Governor of California. Zoltan has spoken at Parliaments and Senates around the world, appeared on The Joe Rogan Experience, consulted for the US Armed Forces, and served as a correspondent for The New York Times. He has addressed the World Bank, the World Economic Forum, and the UK Parliament, and his work has influenced world leaders while shaping global conversations on AI, liberty, and human enhancement. Trained in philosophy and ethics at Columbia University and the University of Oxford, Zoltan brings rare depth to the intersection of technology, biology, and governance. Together, they explore whether aging should be classified as a disease, why regulation is slowing breakthroughs in longevity science, and how California could become ground zero for anti-aging innovation. They debate biology versus machine integration, open source technology versus centralized control, and what morphological freedom really means when enhancement technologies move faster than policy. The discussion spans mitochondria, neuroplasticity, brain optimization, stem cells, organ printing, implants, and the ethical risks of surveillance, algorithmic persuasion, and unchecked AI. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, metabolism, functional medicine, anti-aging strategies, supplements, nootropics, ketosis, fasting, carnivore frameworks, sleep optimization, and living Smarter Not Harder in a world increasingly shaped by AI and technology, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why aging may be a solvable problem rather than an unavoidable fate • How politics and regulation influence access to longevity and anti-aging therapies • The real tradeoffs between biological upgrades and machine integration • Why mitochondria, neuroplasticity, and brain optimization matter in human enhancement • How AI and surveillance technology threaten cognitive and biological autonomy • What morphological freedom means for the future of medicine and personal choice • Why open source approaches to biohacking could protect liberty and innovation • How Smarter Not Harder strategies support longevity in a rapidly evolving world Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! BEYOND Conference 2026 | Register now with code DAVE300 for $300 off at https://beyondconference.com/ MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. GOT MOLD? | See what's in your air and save 10% with code DAVE10 at http://gotmold.com/shop EMR-Tek | Get 40% off EMF protection with code DAVE at https://www.emr-tek.com/DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: transhumanism podcast, human cyborg future, biohacking transhumanism, longevity technology podcast, anti-aging technology, human enhancement podcast, cyborg implants future, AI human evolution, aging as a disease, radical longevity science, human performance future, brain optimization technology, mitochondria longevity science, neuroplasticity enhancement, biohacking longevity politics, California longevity policy, morphological freedom body, human augmentation debate, AI risk humanity, surveillance technology health, open source biohacking, stem cell longevity future, organ printing technology, functional medicine future, metabolism longevity science, ketosis fasting longevity, nootropics brain optimization, supplements longevity science, carnivore diet longevity, sleep optimization performance, Dave Asprey transhumanism, Zoltan Istvan podcast, futurist longevity interview, governor cyborg policy, technology immortality debate Resources: • Learn More About Zoltan's Work At: https://zoltanistvan.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 3:51 – What Is Transhumanism 8:15 – Biology vs Technology 12:53 – Government & Regulation 20:43 – Running for Governor 26:13 – Social Media & Kids 30:18 – Life Extension & Upgrades 38:59 – Defining Humanity 46:12 – Consciousness & Uploading 49:27 – Religion & Society 58:02 – AI Existential Risk 1:02:57 – Space & Future Enhancement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
How much protein should you eat? Guest Bio: Holli Ryan is a food and nutrition expert, registered and licensed dietitian-nutritionist, health and wellness writer, blogger, and senior digital marketing specialist. She graduated from Florida International University and is a member of the Academy of Nutrition and Dietetics. In her free time, she enjoys photography, travel, cooking, art, music, and nature.
How much protein should you eat? The new 2025-2030 Dietary Guidelines for Americans are shaking up the nutrition landscape! In this episode of Live Foreverish, Dr. Crystal sits down with registered dietitian, Holli Ryan, to discuss major updates, including the return of full-fat dairy and increased protein recommendations. The conversation also explores challenges in implementing these changes at home and in schools, conflicting messages about fat, and the removal of specific alcohol limits. #LELEARN #EDULFsocial Guest Bio: Holli Ryan is a food and nutrition expert, registered and licensed dietitian-nutritionist, health and wellness writer, blogger, and senior digital marketing specialist. She graduated from Florida International University and is a member of the Academy of Nutrition and Dietetics. In her free time, she enjoys photography, travel, cooking, art, music, and nature.
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Drs. Cousens and Murray share their top longevity picks: a multivitamin, vitamin D3, EPA/DHA, magnesium, and mineral-rich salt. #LongevitySupplements #AntiAging #WellnessBasics
Melatonin and dementia
Melatonin and dementia A balanced circadian rhythm and healthy sleep affect brain health over time. At the center of this equation is melatonin. In this episode of Live Foreverish, hosts Dr. Mike and Dr. Crystal explore current research investigating melatonin's role in brain health and dementia. They discuss how circadian rhythm and sleep quality relate to cognitive aging, potential mechanisms, and practical considerations for talking with your healthcare provider about melatonin. #LELearn #EDULiveforeverish
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Dr. Gabriel Cousens opens with how dancing, joyful relationships, and spiritual love improve flexibility, brain function, and life expectancy. #LongevitySecrets #JoyfulLiving #HolisticHealth
Living a grateful life Guest Bio Jamie Hess is a TEDx and keynote speaker, media personality and entrepreneur. She is a lifestyle expert and the host of The Gratitudeology™ Podcast (featured on the TODAY Show). Prior to becoming a highly sought after content creator, Jamie spent 17 years as a senior level PR and marketing expert on brands like McDonald's, General Motors, LinkedIn, Barry's Bootcamp, and W Hotels Worldwide. Today, she integrates her expertise to teach people how to expertly optimize and leverage their own personal brand through her course, Brand Ninja, where she helps solopreneurs, side hustlers, and thought leaders achieve the high-paying brand deals of their dreams. Jamie is an on-air personality for QVC, leveraging her love for brands to help America buy their favorite products. She also contributes healthy living advice to hundreds of shows, including TODAY, Good Morning America, The View, and beyond.
Living a grateful life The healing power of gratitude is undeniable, but at times it's easier said than done. In this episode of Live Foreverish, we sit down with Jamie Hess, who shares her personal gratitude journey and everyday strategies to cultivate gratitude in daily life. #LELearn #EDULiveforeverish Guest Bio Jamie Hess is a TEDx and keynote speaker, media personality and entrepreneur. She is a lifestyle expert and the host of The Gratitudeology™ Podcast (featured on the TODAY Show). Prior to becoming a highly sought after content creator, Jamie spent 17 years as a senior level PR and marketing expert on brands like McDonald's, General Motors, LinkedIn, Barry's Bootcamp, and W Hotels Worldwide. Today, she integrates her expertise to teach people how to expertly optimize and leverage their own personal brand through her course, Brand Ninja, where she helps solopreneurs, side hustlers, and thought leaders achieve the high-paying brand deals of their dreams. Jamie is an on-air personality for QVC, leveraging her love for brands to help America buy their favorite products. She also contributes healthy living advice to hundreds of shows, including TODAY, Good Morning America, The View, and beyond.
Inulin, fatty fish, and foot and ankle comfort
Inulin, fatty fish, and foot and ankle comfort Listen to the latest episode of Live Foreverish as Drs. Mike and Crystal discuss how a prebiotic fiber can help with functional constipation; food as medicine with product prescriptions; how B vitamins help NSAIDs work better; and the best diet for fatty liver disease. #LELearn #EDULiveforeverish
Nutritional support for chronic venous insufficiency
Nutritional support for chronic venous insufficiency Struggling with leg pain, swelling or varicose veins? Listen to the latest episode of Live Foreverish with Drs. Mike and Crystal to learn what chronic venous insufficiency is, what causes it, how to spot symptoms early, and which natural nutrients may support vein health and blood flow. #LELearn #EDULiveforeverish
Lifestyle strategies for restless leg syndrome
Lifestyle strategies for restless leg syndrome Are you tired of that uncontrollable urge to move your legs, especially at night? You might be experiencing restless leg syndrome, a neurological disorder that can severely impact your sleep and quality of life. In this episode of Live Foreverish, Dr. Mike and Dr. Crystal discuss the symptoms, risk, leading causes, and nutritional solutions for better comfort. #LELEARN #EDULFsocial
DHEA's perks for mood, bones, and immunity
DHEA's perks for mood, bones, and immunity Curious about DHEA and healthy aging? In this episode of Live Foreverish, Dr. Mike and Dr. Crystal break down what happens as DHEA levels decline with age, why it matters, and how to know if it's something you should replace. #LELEARN #EDULFsocial
Hormone replacement therapy options
Hormone replacement therapy options If you've ever wondered whether hormones could be affecting your sleep, libido, weight, focus, or overall well-being, this is the perfect conversation to learn where to begin. In this episode of Live Foreverish, we sit down with Carolyn Zaumeyer, MSN, APRN, a bio-identical hormone expert, and dive into everything you've wanted to know about hormone replacement therapy. #LELearn #EDULiveforeverish
The latest nutritional findings on statin side effects, ways to improve brain blood flow and heart health
The latest nutritional findings on statin side effects, ways to improve brain blood flow and heart health In this “ins and outs” episode of Live Foreverish, Dr. Mike and Dr. Crystal discuss how CoQ10 reduced statin-associated muscle symptoms; the link between peanut consumption and improved memory; the health benefits of sesame seeds; and how greater exposure to artificial light at night increases the risk of cardiovascular disease. #LELEARN #EDULFsocial
Histamine intolerance Guest Bio: Adriana Duelo is a Registered Dietitian with over 15 years of clinical experience, Researcher at the University of Barcelona, and Director of the DAO Institute, which is currently present in 31 cities across 16 countries, including the United States.
Histamine intolerance If digestive issues and regular enzymes aren't working, it could be histamine! In this episode of Live Foreverish, Dr. Mike and Dr. Crystal hear insights into the latest research from registered dietitian Adriana Duelo, who explains the role of histamine in the body, causes and symptoms of excess histamine and intolerance, the pros and cons of following a low histamine diet, and a simple strategy to improve symptoms. #LELearn #EDULiveforeverish Guest Bio: Adriana Duelo is a Registered Dietitian with over 15 years of clinical experience, Researcher at the University of Barcelona, and Director of the DAO Institute, which is currently present in 31 cities across 16 countries, including the United States.
Screening, evaluation, and CVD risk assessment
Screening, evaluation, and CVD risk assessment Medical science has finally recognized the link between chronic, low-grade inflammation and cardiovascular disease! In this episode of Live Foreverish, Dr. Mike and Dr. Crystal share the details on the latest guidelines published by the Americal College of Cardiology which provides action forward steps you can take today to detect and decrease your risk of having a heart attack or stroke. #LELearn #EDULiveforeverish
Voyager Technologies and Infleqtion have announced a strategic partnership to advance dual-use quantum technology in low-Earth orbit (LEO) and beyond. Xairos UK has been selected by Raymetrics and the European Space Agency (ESA) for the delivery of a Quantum Receiver for the Observatories to Optical Ground Stations project. SES and Infinite Orbits have signed an agreement for one geostationary satellite life extension mission, and more. Remember to leave us a 5-star rating and review in your favorite podcast app. Be sure to follow T-Minus on LinkedIn and Instagram. T-Minus Guest Our guest today is Dr. Saralyn Mark, MD, President of iGIANT. You can connect with Dr. Mark on LinkedIn and learn more about iGIANT on their website. Selected Reading Voyager and Infleqtion Partner to Launch Quantum Era in Space European Space Agency and Raymetrics Select Xairos as Subcontractor for ESA Project Newsflash: SES and Infinite Orbits to Collaborate in Europe's First Commercial Life Extension Mission SES, Relativity Space Expand Multi-Launch Agreement for Terran R SFL Missions Inc. Awarded Contract for Additional GHGSat Greenhouse Gas Monitoring Microsatellites BlueOrigin.com/Live NATO, Industry and Innovators discuss Arctic space security Cooperation with Vast in the Field of Space Technologies Established A giant inflatable bag could catch asteroids and space junk- CNN Share your feedback. What do you think about T-Minus Space Daily? Please take a few minutes to share your thoughts with us by completing our brief listener survey. Thank you for helping us continue to improve our show. Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at space@n2k.com to request more info. Want to join us for an interview? Please send your pitch to space-editor@n2k.com and include your name, affiliation, and topic proposal. T-Minus is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices
Uterine fibroids explained Guest Bio Dr. John Lipman, MD, is the Founder and Medical Director of the Atlanta Fibroid Center, a state-of-the-art medical facility that specializes in the nonsurgical treatment of uterine fibroids and has cared for women from throughout the world.
- Announcements and Interviews on Brighteon (0:00) - Health News and Canadian Government's Actions (4:26) - China's Research on Grape Seed Extract (10:40) - Tour of the New Lab and Health Ranger Store (22:29) - Economic Depression and Living Broke (41:19) - Canadian Government's Mass Extermination Plans (1:09:33) - Interview with John Roy from Dawson Knives (1:19:58) - American-Made Manufacturing and Innovation (1:21:24) - Pro Cut Steel and Frog Lube (1:22:43) - Black Friday Sale and Economic Challenges (1:24:57) - Innovations and Future Plans (1:36:51) - Customer Feedback and Design Features (1:45:01) - Supply Chain and Regulatory Challenges (1:50:31) - Commitment to Quality and Craftsmanship (1:50:51) - Future Innovations and Technological Advancements (1:51:30) - Customer Engagement and Marketing Strategies (1:58:09) - Final Thoughts and Future Plans (2:04:42) - America's Health Crisis and the Role of Big Pharma (2:05:31) - Economic and Social Collapse Scenarios (2:16:54) - Military and Police State Preparedness (2:35:21) - AI and Robotics in Warfare (2:40:01) - Economic and Social Implications of Collapse (2:42:37) - Technocracy and Universal Basic Income (2:51:04) - Globalist Plans and Resistance (2:58:06) - Economic and Political Challenges (3:02:29) - Preparation and Survival Strategies (3:02:45) - Black Friday Sale and Health Ranger Store (3:02:58) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com
Uterine fibroids explained Myomectomy and hysterectomy are two common surgical options presented to women with uterine fibroids, but a less invasive alternative is often overlooked. In this Live Foreverish episode, Dr. Mike and Dr. Crystal sit down with Dr. John Lipman to discuss the uterine fibroid embolism procedure and how it is transforming women's lives. #LELEARN #EDULFsocial Guest Bio Dr. John Lipman, MD, is the Founder and Medical Director of the Atlanta Fibroid Center, a state-of-the-art medical facility that specializes in the nonsurgical treatment of uterine fibroids and has cared for women from throughout the world.
Health benefits of nicotinamide, CRP blood test, and resveratrol
In this episode, Chris Burris, founder and chief scientist at My Vital C, discusses his journey into longevity research, the discovery of the ESS-60 molecule, and its implications for health and wellness. He shares insights on the transition from industrial applications to the supplement industry, the importance of testimonials, and the mechanisms behind the molecule's effects on oxidative stress and inflammation. Chris also emphasizes the need for careful consideration when navigating the supplement market and offers practical tips for improving health and longevity.What we cover in this episode:How a Nobel Prize-winning molecule (ESS60) extended lifespan by 90% in animal studiesThe transition from industrial applications to health supplements driven by customer demand.The BOSS theory and how the ESS-60 molecule buffers oxidative stress.Smart ways to stack ESS60 with other longevity supplementsThe main drivers of aging and natural ways to slow them down.Common supplement scams and how to identify safe, high-quality products.The importance of sleep and its impact on overall health.Sponsors:Free Webinar to Heal Your Autoimmune Disease and Mystery Symptoms: https://www.naturalhealthrising.net/webinar EQUIP Prime Protein: https://www.equipfoods.com/NHR15 Save 15% off with code: NHR15Connect with Chris and MyVitalC:Instagram: https://www.instagram.com/myvitalcFacebook: https://www.facebook.com/myvitalcTikTok: https://www.tiktok.com/@myvitalcYouTube: https://www.youtube.com/@MyVitalC/videosLive Longer and Better book: https://amzn.to/48TKJuETry MyVitalC:Special discount for listeners: https://www.myvitalc.com/pages/nhr/?ref=nhrConnect with Rachel:Free Health Consultation with Rachel: https://www.naturalhealthrising.net/health-consultationFree Webinar to Heal Your Autoimmune & Mystery Symptoms: https://www.naturalhealthrising.net/webinarFree Energy Reboot Plan: https://www.naturalhealthrising.net/energy-reboot-planWebsite: https://naturalhealthrising.com/Support this podcast: https://anchor.fm/rachel-smith11/support
Health benefits of nicotinamide, CRP blood test, and resveratrol In this “ins and outs” episode of Live Foreverish, Dr. Mike and Dr. Crystal discuss how nicotinamide reduces the risk of skin cancer; a medical update on C-reactive protein and cardiovascular risk; how resveratrol protects against neurodegeneration and neuroinflammation in individuals with Alzheimer's disease; and why you should not take your phone with you to the bathroom. #LELEARN #EDULFsocial
Physical Signs of Longevity
Physical Signs of Longevity Is there a way to predict how long you will live? Possibly! Certain areas of the world are known for having long-lived populations of people and there are common indicators noted in these groups. In this episode of Live Foreverish, Dr. Mike and Dr. Crystal detail the physical predictors of health such as grip strength, balance, sit-and-stand test, and many more. #LELEARN #EDULFsocial
Dr. Aubrey de Grey, a biomedical gerontologist and pioneer in radical life extension, and founder of the Longevity Escape Velocity Foundation (LEVF), which advances research … Read more The post Dr. Aubrey de Grey on Radical Life Extension and the Future of Aging appeared first on Top Entrepreneurs Podcast | Enterprise Podcast Network.
Solutions to manage PMS Guest Bio Somashekara Nirvanashetty, PhD, Co-Founder & Chief Scientific Officer, Olene Life Sciences Private Limited, is an accomplished biochemist with over 20 years of experience in pharmaceutical, nutraceutical, and agri-food innovation. He holds a PhD from Swinburne University of Technology, Australia, in collaboration with IIT-Madras. Dr. Somu has filed more than 45 patents, authored 10 peer-reviewed publications, and contributed to two book chapters.
Solutions to manage PMS Research is expanding in the field of premenstrual syndrome (PMS) and women are finding monthly relief with everyday nutritional interventions. In this Live Foreverish episode, Dr. Mike and Dr. Crystal sit down with Dr. Somashekara to discuss how PMS differs from other menstrual-related conditions, underlying causes, and nutritional extracts that can help. #LELEARN #EDULFsocial Guest Bio Somashekara Nirvanashetty, PhD, Co-Founder & Chief Scientific Officer, Olene Life Sciences Private Limited, is an accomplished biochemist with over 20 years of experience in pharmaceutical, nutraceutical, and agri-food innovation. He holds a PhD from Swinburne University of Technology, Australia, in collaboration with IIT-Madras. Dr. Somu has filed more than 45 patents, authored 10 peer-reviewed publications, and contributed to two book chapters.
Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You'll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn: • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK's chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain': https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog You will learn: What holds up new treatments for diseases and conditions How long the FDA sits on a known safe medical medication before it is released to the public. Why safe and effective drugs are NOT approved by the FDA Why doctors are forced to use medications off label How you can help During my 44 years of medical practice, I have encountered conditions for which there is no approved medication or surgical treatment available as recognized by the American College of OBGYN or the FDA. This situation can present challenges both for physicians managing these patients and for individuals seeking relief from their symptoms. This issue is not often addressed on Dr Oz, in the news, or at medical conferences. For many conditions, physicians wait for the development of approved medications or treatments, and in the meantime may inform patients that there is currently no treatment or cure available. Some doctors may attribute a patient's concerns to aging, stating that it is a universal experience. While this may be accurate, such explanations may not provide comfort to patients seeking solutions to their symptoms. This lack of helpful guidance can discourage individuals from seeking medical care when they feel their concerns are not acknowledged. This seems to result from insurance companies prioritizing cost savings by minimizing patient care. Every year insurance companies decrease what they pay doctors for their services, while their expenses go up, and the Government requires more and more work behind the scenes like HIPPA, OSHA, and Clia requirements that costs more to deliver the same service. If you have a problem with the time your doctor spends with you then blame the insurance companies whose profits rise every year…Soon doctors will do what I do and only take cash. The practice of medicine is not working in a free market. While insurance limits the prescriptions of medication to those meds that are FDA Approved, the FDA and medical specialty colleges often delay approval of new, low-risk treatments for up to 20 years after their effectiveness is demonstrated. This lengthy process should be reconsidered to treat people who are ill and suffering, now. There is plenty of research in the medical journals that explain the safety of new and effective treatments that can save peoples' lives that are not FDA approved yet. The FDA is not interested in expediting the release of medication/ devices quickly to those people who need help now. They drag out the testing of a medicine that has been effective for years and may or may not approve it. On the flip side they have approved many drugs that later are found to have severe side effects, and they just change the warnings on the medication inserts. They don't take them off the market except in severe cases. Drugs that have worked treating patients successfully are being used but are not FDA approved. These “grandfathered drugs” don't need to go through the testing that new drugs go through because they work with few well-known risks. I use many if these medications because they are inexpensive for my patients and are often more effective than new meds for the same problem. One of the drugs that the FDA has not had to approve is Armour Thyroid, a natural thyroid replacement. My experience with treatments not approved by the FDA Armour Thyroid: Armour Thyroid (AT) has been prescribed by doctors to replace thyroid hormones for about 100 years. It is natural, made from Pig thyroid. It only comes from “medical Pigs” that are raised for medical purposes. We use medical pigs for skin grafts, and other parts of the pig to treat human diseases like heart valve replacements. Armour Thyroid is composed of the four thyroid hormones that humans make: T4, T3, T2, T1. The synthetic thyroid replacement, Synthroid/levothyroxine is only T4. The active form of thyroid is T3, and it requires an enzyme to convert T4 into T3. If a person can't convert T4 into active T3 then nothing improves except the blood levels of T4, and TSH. The majority of women cannot convert T4 into T3. Therefore, if they take Synthroid or levothyroxine and their doctor only checks their TSH level and not the level of free T3 and free T4 to see if the Thyroid is working, then women are told that they are healed, yet they know they are not because none of their low thyroid symptoms are resolved. When this happens, doctors tell female patients that it is all in their heads and dismiss us when we tell them we are not cured with this synthetic T4 medication. Yet Synthroid is a chemical, and AT is natural from medical pigs, so the FDA is trying to Bann the only drug that has successfully treated millions of women. PS. Synthroid was not tested on women like many other drugs that were passed through the FDA before 2014! If you think this is a small problem, think again. Thyroid hormones are vital to human life, and the thyroid gland requires Iodine in the diet. The Midwest US has no Iodine in the soil or water. Therefore, this area is overburdened with hypothyroidism. I have been on AT for 50 years without complication and I have prescribed it thousands of times ever since I went into private practice. AT works to relieve the symptoms of hypothyroidism for women and men, and it works better for women that the “new” drug Synthroid/levothyroxine, which is FDA approved. You ask how could the FDA approve a drug that doesn't successfully treat women? It is because Synthroid was not tested on women! Until 2014 the FDA did not test women in the required drug trials. AT works for us (women), Levothyroxine does not. Now the FDA wants to ban AT. It is not approved because it was around for decades before they started testing medications like they do now, and the history of successful treatment should stand on its own merit! Example 2: Bio-Identical Hormones BIH: BIHs had not been approved by the FDA until recently and there was no announcement that they are now approved for women who have hormone deficiency symptoms or postmenopausal symptoms. Most doctors and women who have been afraid of the only hormones that can help them, bioidentical hormones, haven't yet been told that NOW, FINALLY the medical colleges and the FDA finally have quietly approved BI hormones. There are no pure estradiol and pure testosterone pellets that are made by a drug company for women. My patients get their estradiol and testosterone pellets from a compounding pharmacy. I have been prescribing BIH since 1985 without FDA approval because the oral estrogen formulations that were available at pharmacies caused weight gain and put women at high risk for blood clots. Non-oral BI hormones have fewer risks than FDA approved estrogens. I waited more than 45 years for the FDA to approve BI hormones for treatment of women. All those women in the last 45 years who were taking FDA approved estradiol and those who couldn't tolerate them have been harmed by FDA goals of never approving compounded or bio-identical hormones. The delay has harmed 50% of American women. Example #3 Devices for Weight Loss I was involved in the discovery and testing of a unique device that stimulated acupuncture points with a TENS-unit-type patch connected to your cell phone for easy adjustment of your hunger or “fullness”. The FDA requires testing to approve any new device so the group of investors I was part of had to invest thousands of dollars for a device we already knew worked. The FDA told the investigators of all new devices who they should test, who they can't have in the study, and how long the testing should take. I found their parameters for the study of this device to be unrealistic. The women in our test group could not be taking hormones of any kind (birth control, ERT, HRT), and could not be on antidepressants, could not have diabetes or insulin resistance or be on any drug that assisted in weight loss. These women subjects had to be a certain BMI (level of obesity) and had to be tested repeatedly with weight and body composition measurements None of my patients who needed weight loss could participate. Most GYN patients are on some medication or supplement, so the FDA made this study of our device so narrow that REAL WOMEN weren't tested! Sadly, we lost many women in the control group from the study because they were NOT losing weight while the ones on the device were obviously dropping pounds, so we had trouble maintaining test subjects. The testing phase of this simple device took 7 years! Our device works and no one will ever know about it or be able to use this non-medicinal weight loss device because when the FDA rejects your device you will be breaking the law if you produce and sell it directly to the public. It has no side effects or dangers..it just controls the amount you eat with stimulation of an acupuncture point. There are many ways to change this situation, and it takes years and billions of dollars to change the whole system of bringing treatments to patients quickly. I'm afraid I won't see a revolution of the way we bring medicines and devices to market during my lifetime. Currently there is a 17-year delay between proving a drug or device works for a particular illness or condition and when it becomes available to doctors and patients. So what do we do in the meantime? I seek treatments for patients who are unresponsive to traditional medicine by reading journals like Life Extension, that inform doctors and patients alike about new effective solutions for common medical complaints and diseases that the FDA has ignored or stymied with endless drug trials. Life Extension Magazine highlights studies on new medications for diseases without an FDA approved solution and publicizes diagnostic tests often overlooked by mainstream publications because they are not yet FDA approved. The medical journals I read (New England Journal of Medicine, JAMA, Menopause, Metabolism and Endocrinology, Journal of Age management, to name a few) offer treatments for orphan diseases or even common problems that haven't been blessed by the FDA. It takes an average of 17 years from the culmination of research on a new drug, test or device until it is approved for use by the public! At the end of this Blog, I will give you a link to make your voice heard by signing a petition to shorten the approval of new treatments and medications from the average of 17 years to 3 years! My patients don't have time to wait for relief, and that may be the case for you as well. If you want to do something to help, please click this link and let the FDA know how you feel. Please sign a Petition to enact an amendment to the FOOD, DRUG and COSMETIC ACT, by going to: https://age-reversal.net/fda/
Can ultra-processed foods be healthy?
Can ultra-processed foods be healthy? Are ultra-processed foods really harmful—or can they fit into a balanced diet? In this episode of Live Foreverish, Dr. Mike and Dr. Crystal hear insights on the latest research from Dr. Richard Black, who has over 30 years of experience in the packaged food industry. He shares strategies and tools to help you make smarter, science-based food choices for better health. #LELearn #EDULiveforeverish
This week on Binchtopia, Eliza returns from her off-grid era to dive into the history and evolution of body technology, from ancient tracking rituals to Silicon Valley's quantified self movement. The girlies break down Fitbits, Oura Rings, Prenuvo scans, and sleep apps to examine how our obsession with optimizing the body blurs the line between health, surveillance, and control. Digressions include Taylor Swift's public clowning, Nicki Minaj and Cardi B beefing with each other's kids, and the biological necessity of annihilation anxiety. This episode was produced by Julia Hava and Kylie Finnigan and edited by Livi Burdette. SOURCES A Panopticon on My Wrist: The Biopower of Big Data Visualization for Wearables Beyond Human: Lifelogging and Life Extension Denial of Death by Ernest Becker Effectiveness of wearable activity trackers to increase physical activity and improve health: a systematic review of systematic reviews and meta-analyses Exploring the impact of commercial wearable activity trackers on body awareness and body representations: A mixed-methods study on self-tracking Full-body MRIs: Peace of mind for some, "bane of my existence" for others Health Wearables, Gamification, and Healthful Activity I covered my body in health trackers for 6 months. It ruined my life. Interventions Using Wearable Activity Trackers to Improve Patient Physical Activity and Other Outcomes in Adults Who Are Hospitalized Know Thyself: Tracking Every Facet of Life, from Sleep to Mood to Pain, 24/7/365 Memex: A Romantic Theoretical Tool for Thought Orthosomnia: Are Some Patients Taking the Quantified Self Too Far? Perceptions of Wearable Health Tools Post the COVID-19 Emergency in Low-Income Latin Communities: Qualitative Study Prevalence of Orthosomnia in a General Population Sample: A Cross-Sectional Study Ring of power: Oura will soon be worth $11b Self-Tracking by Gina Neff & Dawn Nafus Terror Management Theory The double-edged sword of self-tracking: investigating factors of technostress in performance-oriented cycling and triathlon The Quantified Self by Deborah Lupton The Rise of Wearable Devices during the COVID-19 Pandemic: A Systematic Review Wearable Devices Can Increase Health Anxiety. Could They Adversely Affect Health? Wearable Devices to Improve Physical Activity and Reduce Sedentary Behaviour: An Umbrella Review Wearable systems without experiential disruptions: exploring the impact of device feedback changes on explicit awareness, physiological synchrony, sense of agency, and device-body ownership White Noise by Don Delillo Will a Full-Body MRI Scan Help You or Hurt You?
Doctors Break Down the Latest Nutritional Findings
Doctors Break Down the Latest Nutritional Findings In this “ins and outs” Live Foreverish episode, Dr. Mike and Dr. Crystal share new research using melatonin to improve motor skills and mental health in MS patients. They also highlight the benefits of weighted vests; two antioxidants that help to manage Graves' disease; and the proper way to measure blood pressure at home. #LELEARN #EDULFsocial
The psychology of dietary preferences Guest Bio: Catherine A. Forestell, Ph.D., is a Professor of Psychological Sciences at William & Mary. Her research examines the development of food preferences and eating behaviors across the lifespan, with an emphasis on the biological, psychological, and cultural factors that shape dietary choices. She has published extensively on topics including infant feeding practices, sensory perception, and the psychology of vegetarianism and plant-based diets.
The psychology of dietary preferences Vegetarian and plant-based diets have well-established health benefits, but sticking to them can be challenging. In this episode of Live Foreverish, Dr. Mike and Dr. Crystal sit down with Dr. Catherine Forestell to discuss vegetarianism and how it relates to well-being. We also discuss the personality type that allows someone to stick with it long-term and why some people find this approach difficult to follow. #LELEARN #EDULFsocial Guest Bio: Catherine A. Forestell, Ph.D., is a Professor of Psychological Sciences at William & Mary. Her research examines the development of food preferences and eating behaviors across the lifespan, with an emphasis on the biological, psychological, and cultural factors that shape dietary choices. She has published extensively on topics including infant feeding practices, sensory perception, and the psychology of vegetarianism and plant-based diets.
The top five most popular functional foods
The top five most popular functional foods From probiotics in yogurt to omega-3s in fish, discover how certain foods offer benefits beyond basic nutrition. In this science-packed episode of Live Foreverish, Dr. Mike and Dr. Crystal dive into the world of functional foods—what they are, how they work, and which ones top the list for supporting heart health, immunity, and more. #LELearn #EDULiveforeverish
Dr. Derya Unutmaz joins Dr. Buck Joffrey to discuss the critical role of T cells in the immune system, their changes with aging, and the implications for chronic diseases. He emphasizes the importance of thymus regeneration and the microbiome's influence on health. The discussion also covers advancements in engineering immune cells for cancer treatment and the potential of AI in revolutionizing aging research and drug discovery. Unutmaz expresses optimism about the future of aging research, highlighting the need for a shift in how aging is perceived in the medical community. Learn more about Dr. Derya Unutmaz: https://www.jax.org/research-and-faculty/faculty/derya-unutmaz - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
What if death isn't inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You'll learn why some of today's top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondria, and your entire approach to life. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with philosopher and best-selling author Dr. Stephen Cave, Director of the Institute for Technology and Humanity at the University of Cambridge. With decades of expertise studying death, immortality, and ethics, Dr. Cave brings a rare depth of insight into how our desire to live longer intersects with neuroplasticity, supplements, and even nootropics. Together, they unpack the four universal immortality narratives, the dangers of mind uploading, and why AI might become humanity's next god or destroyer. You'll discover how legacy, ego, functional medicine, and even fasting and ketosis play into our fear of death. The conversation also dives into the deeper psychological and societal consequences of radical life extension, and what happens when biohacking crosses into belief. This episode is a must-listen for anyone serious about hacking longevity, brain optimization, metabolism, and building a future where living to 180 isn't science fiction. You'll also hear surprising thoughts on Danger Coffee, RFK, sleep optimization, and how to approach mortality using the Smarter Not Harder mindset. You'll Learn: • Why all technology is a form of life extension • How ego and boredom threaten longevity more than disease • The real dangers of digital immortality and uploading consciousness • Why procrastination could be the enemy of eternal life • How to balance transhumanist tech with human values • The surprising connection between cold therapy, supplements, and meaning Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Stephen's Website: https://www.ith.cam.ac.uk/staff/stephen-cave • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:09 Intro • 01:39 Life Extension Challenges • 02:05 Boredom and Mental Health • 04:28 Immortality vs. Enlightenment • 06:21 Death's Role in Civilization • 09:06 Life Stages and Aging • 10:41 Global Immortality Narratives • 15:50 Personal Takes on Immortality • 20:46 Biohacking and Longevity • 28:43 Transhumanism Today • 31:00 Techno-Utopianism and Happiness • 32:20 Wealth and Fulfillment • 32:54 Purpose and Meaning • 34:00 Legacy and Death • 36:33 Near-Death and Mortality • 37:52 Time and Procrastination • 42:00 AI and Human Future • 45:56 Ethics of Life Extension • 50:35 Autonomy and Mortality • 52:35 Dangerous Ideas in Longevity • 55:53 Advice for the Young See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.