SELF Principle

Welcome to our weekly live series where we discuss all topics related to kidney health, nutrition, and longevity.Timestamps00:00 Start0:30 Introduction1:15 Sodium and Kidney Disease7:12 Nanoplastics in bottled water16:09 Tirzepatide and protein in the urine23:12 Exercise and Longevity26:33 Artificial sweeteners and Gut MicrobiomeReferences:1. Sodium and CKD-World Health Organization . Guideline: Sodium Intake for Adults and Children. World Health Organization; Geneva, Switzerland: 2012. pp. 1–46.-Wright JA, Cavanaugh KL. Dietary sodium in chronic kidney disease: a comprehensive approach. Semin Dial. 2010 Jul-Aug;23(4):415-21.-Verma A, Popa C. The Interplay Between Dietary Sodium Intake and Proteinuria in CKD. Kidney Int Rep (2023) 8, 1133–11362. Nanoplastics and Health-Qian, N., et al. (2024). "Rapid single-particle chemical imaging of nanoplastics by SRS microscopy." Proceedings of the National Academy of Sciences 121(3): e2300582121.3. Tirzepatide and Proteinuria-Karakasis et al. Effect of tirzepatide on albuminuria levels and renal function in patients with type 2 diabetes mellitus: A systematic review and multilevel meta-analysis .Diabetes Obes Metab 2023 Dec 20;[EPub Ahead of Print]4. Walking and longevity-Kankaanpää A, Tolvanen A, Joensuu L, Waller K, Heikkinen A, Kaprio J, Ollikainen M, Sillanpää E. The associations of long-term physical activity in adulthood with later biological ageing and all-cause mortality - a prospective twin study. medRxiv [Preprint]. 2023 Jun 5:20235. Artificial Sweeteners and gut microbiome-Hosseini A, Barlow GM, Leite G, Rashid M, Parodi G, Wang J, Morales W, Weitsman S, Rezaie A, Pimentel M, Mathur R. Consuming artificial sweeteners may alter the structure and function of duodenal microbial communities. iScience. 2023 Nov 23;26(12):108530.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

ver wondered how to significantly increase your life expectancy? In this video, we delve into a groundbreaking study that reveals 8 simple but powerful habits you can adopt right now to add up to 24 more years to your life. From veterans to the general population, these insights are essential for anyone interested in health, wellness, and longevity.What you'll learn:The incredible study involving 720,000 U.S. veterans.How to add years to your life starting at 40, 50, or 60.8 specific habits and their surprising effects on longevity.Tips and inspiration to make these life-changing adjustments.Disclaimer: The information provided is for general knowledge and is not a substitute for individual medical advice. All viewers should consult their physician before starting any medical program or treatment. Any action you take upon the information that you find within this content is strictly at your own risk.  Never disregard professional medical advice or delay in seeking it because of something you have heard on the SELF Principle YouTube channel, Podcast, or website.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Join us as we delve into the fascinating world of Chronic Kidney Disease (CKD) and the unexpected role of a low-protein diet. This episode is packed with vital insights from a groundbreaking study that could change the way we manage CKD. Learn how simple dietary adjustments could potentially delay severe treatments in advanced CKD stages.Reference: Otanie et al. Journal Renal Nutrition. 2023. https://doi.org/10.1053/j.jrn.2023.05.001VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

In this podcast, I discuss the 15 early warning signs of kidney failure that you need to know to protect your kidney health. As one of the most important organs in our body, maintaining good kidney function is essential for overall health. Sadly, kidney failure often develops slowly, and many people may not notice the symptoms until it's too late.I highlight the value of early detection and prevention, as well as the various symptoms related to kidney failure, such as tiredness, swelling, changes in urination, and more. I also explain the basic functions of the kidneys and what causes kidney failure, giving you the knowledge you need to keep your health in check.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Discover the top 5 strategies to lower your risk of kidney stones and improve your overall health. In this podcast, we'll explore the different types of kidney stones, and their risk factors and share practical tips to help you prevent their formation. From maintaining a healthy weight to staying well-hydrated and consuming a balanced diet, we'll guide you through the steps to live a kidney stone-free life. VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

In this podcast, we explore the importance of understanding glomerular filtration rate (GFR) and how it plays a crucial role in maintaining healthy kidneys. We'll discuss factors affecting GFR, the five stages of kidney disease, ways to improve your kidney function, and different equations for calculating eGFR. Learn about actionable tips for maintaining kidney health and discover which eGFR equation is considered the most accurate. Don't forget to like, share, and subscribe for more informative health-related content!VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

In this podcast, I dive deep into the creatinine blood test and its importance for kidney health. Learn about creatinine, how it's measured, its normal levels, and how it relates to kidney function. I also discuss additional tests you may need, what happens if you're diagnosed with kidney disease, and how to manage and prevent kidney problems. Plus, I touch on drugs and supplements that may interfere with creatinine blood tests. Let's explore everything you need to know about creatinine and what it means for your health!VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Discover the surprising findings of the Master@Heart study, which reveals a potential link between intensive endurance exercise and increased coronary plaque risk. Learn what this means for your health.References:-Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber W. Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing. JAMA Netw Open. 2018;1(6):e183605. doi:10.1001/jamanetworkopen.2018.3605-Bosscher et al. Master@Heart Consortium, Lifelong endurance exercise and its relation with coronary atherosclerosis, European Heart Journal, 2023;, ehad152, https://doi.org/10.1093/eurheartj/ehad152VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A new observational study has found that a low-carbohydrate, high-fat diet, commonly known as the keto diet, is associated with a twofold increase in the risk of future cardiovascular events. Watch to learn more about the study's findings and what they mean for those considering a keto diet.References:• Iatan I, et al. Featured Clinical Research II. Presented at: American College of Cardiology Scientific Session; March 4-6, 2023; New Orleans.• Gibson AA, Seimon RV, Lee CM, Ayre J, Franklin J, Markovic TP, Caterson ID, Sainsbury A. Do ketogenic diets really suppress appetite? A systematic review and meta‐analysis. Obes Rev. 2015 Jan 1;16(1):64-76.• Bueno NB, de Melo IS, de Oliveira SL, da Rocha Ataide T. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. Br J Nutr. 2013 Oct;110(7):1178-87.• Sumithran P, Prendergast LA, Delbridge E, Purcell K, Shulkes A, Kriketos A, Proietto J. Ketosis and appetite-mediating nutrients and hormones after weight loss. Eur J Clin Nutr. 2013 Jul;67(7):759.• Paoli A, Bianco A, Grimaldi KA, Lodi A, Bosco G. Long term successful weight loss with a combination biphasic ketogenic mediterranean diet and mediterranean diet maintenance protocol. Nutrients. 2013 Dec 18;5(12):5205-17.• Hu T, Mills KT, Yao L, Demanelis K, Eloustaz M, Yancy Jr WS, Kelly TN, He J, Bazzano LA. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol. 2012 Oct 1;176(suppl_7):S44-54.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Is erythritol, the popular artificial sweetener, actually safe for our hearts? In this video, we dive into a recent study published in Nature Medicine that reveals the potential long-term health effects of erythritol. Despite being labeled as "non-nutritive," "zero calories," or "natural," this sweetener could be putting us at risk for major adverse cardiovascular events (MACE). Learn about the study's findings, which suggest that erythritol increases platelet activity and the formation of blood clots. Watch now to discover if your go-to low-calorie sweetener is putting your heart health at risk.References:Fagherazzi G, Vilier A, Saes Sartorelli D, Lajous M, Balkau B, Clavel-Chapelon F. Consumption of artificially and sugar-sweetened beverages and incident type 2 diabetes in the Etude Epidémiologique auprès des femmes de la Mutuelle Générale de l'Education Nationale–European Prospective Investigation into Cancer and Nutrition cohort–. The American journal of clinical nutrition. 2013 Jan 30;97(3):517-23.Imamura F, O'connor L, Ye Z, Mursu J, Hayashino Y, Bhupathiraju SN, Forouhi NG. Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction. Br J Sports Med. 20 Suez, J. et al. (2022) "Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance", Cell. doi: 10.1016/j.cell.2022.07.016. https://www.cell.com/cell/fulltext/S0092-8674(22)00919-916 Apr 1;50(8):496-504.Debras C. et al. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Med. 2022 Mar 24;19(3):e1003950. doi: 10.1371/journal.pmed.1003950. PMID: 35324894; PMCID: PMC8946744.Witkowski, M., Nemet, I., Alamri, H. et al. The artificial sweetener erythritol and cardiovascular event risk. Nat Med (2023). https://doi.org/10.1038/s41591-023-02223-9VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Are you someone who thinks potatoes are bad for weight loss and insulin resistance? Think again! Potatoes are packed with benefits for your health, including their high resistant starch content and low energy density. They can even promote gut health and lower blood glucose levels. So, if you're looking for a healthy and delicious addition to your diet, consider adding more potatoes to your meals!Reference: Candida J. Rebello, Robbie A. Beyl, Frank L. Greenway, Kelly C. Atteberry, Kristin K. Hoddy, and John P. Kirwan.Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial.Journal of Medicinal Food.Dec 2022.1155-1163.http://doi.org/10.1089/jmf.2022.0072VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Are you aware that your daily eating habits have a significant impact on your mortality risk? In this video, we will explore the latest research findings on the association between meal skipping, shorter meal intervals, and increased risk of all-cause and cardiovascular disease mortality among US adults.Reference: Sun, Yangbo et al. Meal Skipping and Shorter Meal Intervals Are Associated with Increased Risk of All-Cause and Cardiovascular Disease Mortality among US Adults. Journal of the Academy of Nutrition and Dietetics, Volume 123, Issue 3, 417 - 426.e3VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A recent study published in Kidney Medicine found that increased serum bicarbonate levels in kidney transplant recipients can lower the risk of transplant loss and death. Get valuable information for kidney transplant recipients and their healthcare providers.Reference:Mathur V, et al. Kidney Med. 2022;doi:10.1016/j.xkme.2022.100573.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Intermittent fasting has recently gained popularity as a dietary approach for promoting health and longevity. Let's explore the latest research on time-restricted eating and how it impacts gene expression throughout the body, leading to increased life spans.Reference:Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals” by Shaunak Deota, Terry Lin, Amandine Chaix, April Williams, Hiep Le, Hugo Calligaro, Ramesh Ramasamy, Ling Huang and Satchidananda Panda, 3 January 2023, Cell Metabolism. DOI: 10.1016/j.cmet.2022.12.006VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

An interesting new study suggests simply cutting calories is more effect than intermittent fasting. Let's dive into the details and see it that is actually true.References:  Moro T, Tinsley G, Pacelli FQ, Marcolin G, Bianco A, Paoli A. Twelve Months of Time-restricted Eating and Resistance Training Improves Inflammatory Markers and Cardiometabolic Risk Factors. Med Sci Sports Exerc. 2021 Dec 1;53(12):2577-2585. doi: 10.1249/MSS.0000000000002738. PMID: 34649266.Lowe DA, Wu N, Rohdin‐Bibby L, Moore AH, Kelly N, Liu YE, Philip E, Vittinghoff E, Heymsfield SB, Olgin JE, et al. Effects of time‐restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA Intern Med. 2020; 180:1491–1499.  Zhao, D., et al. "Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort." Journal of the American Heart Association 2023(0): e026484.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Almonds are a nutrition powerhouse. Just 57 grams (about 2 handfuls of almonds) contains 12 grams of protein, 17 grams of monounsaturated fat, 6.6 grams of polyunsaturated fat, and 6.6 grams of fiber. This same serving size also provides a 96% daily value of vitamin E, 36% daily value of Magnesium, 1.4 grams of amino acid arginine, and 1.75 grams of branched-chain amino acids (leucine, isoleucine, valine). But can almonds also improve workout recovery? Let's take a look at the research. Reference:-Nieman DC, et al. Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise. Front. Nutr. 2023;doi: 10.3389/fnut.2022.1042719.-Rajaram S, Connell KM, Sabaté J. Effect of almond-enriched high-monounsaturated fat diet on selected markers of inflammation: a randomized, controlled, crossover study. Br J Nutr. 2010 Mar;103(6):907-12. doi: 10.1017/S0007114509992480. Epub 2009 Oct 29. PMID: 19874636.-Fernández-Rodríguez R, Jiménez-López E, Garrido-Miguel M, Martínez-Ortega I, Martínez-Vizcaíno V, Mesas A. Does the evidence support a relationship between higher levels of nut consumption, lower risk of depression, and better mood state in the general population? A systematic review. Nutr Rev. (2022) 80:2076–88. doi: 10.1093/nutrit/nuac022VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

 Could your gut health be the reason for your lack of motivation for exercise? In a study published in the journal Nature, researchers looked at why some mice used their exercise wheel a lot versus others mostly ignored it. Reference:Dohnalová, L., Lundgren, P., Carty, J.R.E. et al. A microbiome-dependent gut–brain pathway regulates motivation for exercise. Nature 612, 739–747 (2022). https://www.nature.com/articles/s41586-022-05525-zVISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Stress can hugely impact our overall health, and one of the risks it poses is an increased risk of cancer. Studies have found that people with high-stress levels are more likely to develop certain types of cancer, including breast, colon, and prostate cancer. Stress can also worsen existing cancer symptoms, making treatment and recovery more complex.  Let's look at a new study examining the link between chronic lifetime stress and cancer death.Reference: Moore JX, et al. SSM Popul Health. 2022;doi:10.1016/j.ssmph.2022.101185.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A plant-based diet is a nutritious and sustainable way to eat. However, it is important to note that not all plant-based diets are equally healthy or environmentally friendly. Let's look at the role of healthy vs. unhealthy plant-based diets and colorectal cancer. VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Losing weight can be difficult but with the help of drugs like Wegovy and Ozempic, it can be made easier. But is the risk of potential side effects worth it? In this video, we'll look at the evidence linking Wegovy and Ozempic to thyroid cancer. We'll discuss the potential risks and benefits of using these drugs to achieve weight loss and help you make an informed decision about their use. So, if you're considering Wegovy and Ozempic, watch this video to learn more.Reference: Bezin J, et al. Diabetes Care. 2022;doi:10.2337/dc22-1148.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

According to new data, higher concentrations of air pollution were linked to greater heart attack risk in Germany. Reference: de Buhr-Stockburger I, et al. Coronary artery disease – Epidemiology, prognosis, outcome 2. Presented at: European Society of Cardiology Congress; Aug. 26-29, 2022; Barcelona, Spain (hybrid meeting).VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Chronic constipation, which affects about 12% of adults, is difficult to treat and accounts for more than 2.5 million visits to medical centers every year. Increasing psyllium fiber by 10 grams daily led to better results than osmotic or stimulant laxatives.Reference: Van der Schoot A, et al. Am J Clin Nutr. 2022;doi:10.1093/ajcn/nqac184VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

What's the relationship between Cognitive function, physical activity, and depressive symptoms? Let's look at the latest research from the SHARE (Survey of  Health, Ageing and Retirement) survey looking at 51K adults form over 25 countriesCsajbók, Z., Sieber, S., Cullati, S. et al. Physical activity partly mediates the association between cognitive function and depressive symptoms. Transl Psychiatry 12, 414 (2022). https://doi.org/10.1038/s41398-022-02191-7VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A new study published in the European Journal of Preventive Cardiology found that drinking ground and instant coffee but not decaffeinated coffee was associated with a reduction in arrhythmias, including atrial fibrillation. Chieng et al. The impact of coffee subtypes on incident cardiovascular disease, arrhythmias, and mortality: long-term outcomes from the UK Biobank, European Journal of Preventive Cardiology, 2022;, zwac189, https://doi.org/10.1093/eurjpc/zwac189VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

We all know that protein is a vital nutrient for muscle-building, but how much do you really need to take to build muscle effectively? According to research, it appears to be between 1.2 and 1.6 grams of protein per kilogram of body weight.References:Ryoichi Tagawa, Daiki Watanabe, Kyoko Ito, Keisuke Ueda, Kyosuke Nakayama, Chiaki Sanbongi, Motohiko Miyachi, Dose–response relationship between protein intake and muscle mass increase: a systematic review and meta-analysis of randomized controlled trials, Nutrition Reviews, Volume 79, Issue 1, January 2021, Pages 66–75, https://doi.org/10.1093/nutrit/nuaa104Tagawa, R., Watanabe, D., Ito, K. et al. Synergistic Effect of Increased Total Protein Intake and Strength Training on Muscle Strength: A Dose-Response Meta-analysis of Randomized Controlled Trials. Sports Med - Open 8, 110 (2022). https://doi.org/10.1186/s40798-022-00508-wNunes et al. Journal of Cachexia, Sarcopenia and Muscle. 2022. https://doi.org/10.1002/jcsm.12922VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A new meta-analysis of 28 studies showed Yoga was associated with the largest mean reduction in HbA1c at 1%, followed by qigong at 0.66% and mindfulness-based stress reduction at 0.48%.Reference: Sanogo F, et al. J Integr Complement Med. 2022;doi:10.1089/jicm.2022.0586VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

In a new study, higher levels of glutathione in the brain were linked to better and more steady performance on motivation-based tasks. Glutathione can be increased by eating more cysteine-rich foods such as poultry, egg, fish, beef, and whole grains, lentils, low fat yogurt, sunflower seeds.Reference: Zalachoras et al. (2022) Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort eLife 11:e77791. https://doi.org/10.7554/eLife.77791VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

According to a new research study, the soleus muscle, which is only 1% of the body weight, is capable of raising its metabolic rate during soleus pushup contractions to easily double, even sometimes triple, the whole-body carbohydrate oxidation.Reference: Hamilton MT, Hamilton DG, Zderic TW. A potent physiological method to magnify and sustain soleus oxidative metabolism improves glucose and lipid regulation. iScience. 2022 Aug 5;25(9):104869. doi: 10.1016/j.isci.2022.104869.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Sleep is essential for good health, but new research suggests that many older adults aren't getting enough of it. A study found that people 50 and older who slept five hours or less at night had a greater risk of developing multiple chronic diseases as they age compared with peers who got a longer night's rest.VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

In a study looking at carb quality, timing and quantity, researchers found that quality of carbs matters and the greatest impact is during dinner time.Study reference: Hou et al. Relationship Between Carbohydrate Intake (Quantity, Quality, and Time Eaten) and Mortality (Total, Cardiovascular, and Diabetes): Assessment of 2003–2014 National Health and Nutrition Examination Survey Participants. Diabetes Care 2022; dc220462. https://doi.org/10.2337/dc22-0462VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

Artificial sweeteners have been around for decades, but lately, there is a lot of controversy surrounding their safety. In this video, we will discuss artificial sweeteners and their effect on the microbiome. The gut microbiome is one of the most important parts of our body, and a lot of research is being carried out to understand its role in a number of health conditions. Some people claim that non-nutritive sweeteners, such as aspartame, sucralose, stevia, and saccharin can alter gut microbiome and increase blood glucose and insulin levels. This may be one reason why people who consume artificial sweeteners are more prone to obesity, type 2 diabetes and other chronic health issues. We will also discuss Saccharin which is the oldest of all non-nutritive sweeteners and the one that has been around for the longest time.Reference: Suez J, Cohen Y, Valdés-Mas R, Mor U, Dori-Bachash M, Federici S, Zmora N, Leshem A, Heinemann M, Linevsky R, Zur M, Ben-Zeev Brik R, Bukimer A, Eliyahu-Miller S, Metz A, Fischbein R, Sharov O, Malitsky S, Itkin M, Stettner N, Harmelin A, Shapiro H, Stein-Thoeringer CK, Segal E, Elinav E. Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance. Cell. 2022;185(18):3307-3328. https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

It is well known that cocoa flavanols can improve cognitive function and blood flow in older patients. This new study shows that cocoa flavanols can improve cognitive function and blood flow in healthy young adults. This is the first randomized, double-blind, placebo-controlled study to evaluate the acute cognitive and cerebral blood flow effects of flavanol-rich cocoa in young, healthy adults. "Our findings demonstrate that the daily intake of cocoa flavanols for two weeks is sufficient to improve the cognitive performance and increase cerebral blood flow in young adults," according to the researchers. "Therefore, our data suggest that daily intake of a cocoa flavanol-containing drink over a longer time period may improve cognitive function in healthy individuals."Reference: Gratton, G., Weaver, S.R., Burley, C.V. et al. Dietary flavanols improve cerebral cortical oxygenation and cognition in healthy adults. Sci Rep 10, 19409 (2020). https://doi.org/10.1038/s41598-020-76...VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd

A new study published in the American Journal of Clinical Nutrition, the COSMOS Trial (Cocoa supplement and multivitamin outcomes study) looked at the role of cocoa flavanols and CVD. The study was a randomized, double-blind, placebo-control trial with 21,442 US adults. The study participants received 500mg of cocoa flavanols, a multivitamin, neither or both. The follow-up period was 3.6 years.Reference: Sesso HD, et al. Am J Clin Nutr. 2022;doi:10.1093/ajcn/nqac055VISIT OUR STOREStore: https://www.selfelements.comFOLLOW USwww.selfprinciple.orgwww. youtube.com/selfprinciplewww.youtube.com/plantbasedkidneyhealthwww.instagram.com/seanhashmimd