Infectious Disease Puscast

On episode #81 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 5/8/25 – 5/21/25. Hosts: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo (NEJM) Remdesivir associated with reduced mortality in hospitalized COVID-19 patients (BMC Infectious Diseases) Real-world evidence shows remdesivir tied to less death in hospitalized COVID patients (CIDRAP) Impact of most promising Ebola therapies on survival (Virology Journal) Bacterial Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams (CID) Diet and Risk for Incident Diverticulitis in Women (Annals of Internal Medicine) The Dynamics of QuantiFERON-TB Gold In-Tube Conversion and Reversion in a Cohort of South African Adolescents(American Journal of Respiratory and Critical Care Medicine) BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection(NEJM) The Impact of Diet on Clostridioides difficile Infection (JID) Cefazolin versus Antistaphylococcal Penicillins for the Treatment of Methicillin-Susceptible Staphylococcusaureus Bacteremia (CMI: Clinical Microbiology and Infection) Fungal The Last of US Season 2 (YouTube) Candida auris is emerging as a prevalent urinary pathogen (PLoS Pathgoens A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis (Science) Outcome predictors of Candida prosthetic joint infections (OFID) Cave-Associated Histoplasmosis Outbreak Among Travelers Returning from Costa Rica — Georgia, Texas, and Washington, December 2024–January 2025 (CDC: MMWR) Parasitic COPEG 25th Anniversary (US Embassy in Panama) USDA suspends southern border livestock imports over New World screwworm threat(CIDRAP) Moxidectin combination therapies for lymphatic filariasis (LANCET: Infectious Diseases Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #80 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/24/25 – 5/7/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Incidence and Timing of Epstein–Barr Virus Whole Blood DNAemia in Epstein–Barr Virus-Mismatched Adult and Pediatric Solid Organ Transplant Recipients (Transplant Infectious Disease) Infant Respiratory Syncytial Virus Immunization Coverage in the Vaccine Safety Datalink: 2023–2024 (American Academy of Pediatrics) Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants (Influenza and other respiratory viruses) Hospital admissions of respiratory infections in infants plungewith nirsevimab RSV antibody (CIDRAP) Time to antiviral treatment in mild–moderate COVID-19 in the emergency department (Internal and Emergency Medicine) Delays in COVID antiviral receipt raised risk of poor outcomes after ED visits by 18%, data suggest (CIDRAP) Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV (MMWR) Bacterial Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis (LANCET: Regional Health) Bridging to transplant: TDM-Guided Outpatient Dalbavancin Therapy in Chronic Granulomatous Disease with deep-seeded Inoperable Abscesses over 11 Months (OFID) Nitrites for Urinary Tract Infection—Time to Say Goodbye? (JAMA: Internal Medicine) Fungal The Last of US Season 2 (YouTube) High Mortality and Associated Risk Factors in Kidney Transplant Recipients with Cryptococcosis – A Nationwide Cohort Study Over a Decade Using USRDS Data (OFID) Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID) Parasitic Performance of a novel P. falciparum rapid diagnostic test in areas of widespread hrp2/3 gene deletion (CID) Prevalence of Anopheles stephensi in the Horn of Africa: a systematic review and meta-analysis (BMC Infectious Diseases) Raising awareness of Demodex mites: a neglected cause of skin disease (Infection) Miscellaneous Scientific Integrity Under Threat: The Role of the IDSA, PIDS, and SHEA Journals in an Evolving Political Landscape (CID) Reasoning on Rounds Volume 2: a Framework for Teaching Management Reasoning in the Inpatient Setting (Journal of General Internal Medicine) Billing for and documentation of provider-to-provider interprofessional consults in infectious diseases (Journal of the Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #79 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/10/25 – 4/23/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral An ancient Epstein-Barr virus genome recovered from a museum penis gourd from Papua (JID) Patterns of Decline in Measles, Mumps, and Rubella Neutralizing Antibodies and Protection Levels Through 10 Years After a Second and Third Dose of MMR Vaccine (OFID) Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo(NEJM) Bacterial Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay(Science Translational Medicine) New handheld device can diagnose TB without a lab in under an hour, its developers say(CIDRAP) Maternal mastitis and streptococcal toxic shock syndrome risk from breastfeeding children with scarlet fever (LANCET: Infectious Diseases) Risk Factors for Mortality Among Older Adults with Hospital-Acquired Bloodstream Infections in the Intensive Care Unit(Infectious Diseases and Therapy) Bacteremia in Pediatric Solid Organ Transplant Recipients within 1 Year of Transplant(Transplant Infectious Disease) Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1) (LANCET) Consequences of Climate Change on the Emergence of Pathogenic, Environmentally Acquired Nontuberculous Mycobacteria (OFID) Addition of Macrolide Antibiotics for Hospital Treatment of Community-Acquired Pneumonia (JID) Point-of-Care Testingby Multiplex-PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation(Transplant Infectious Disease) Fungal The Last of US Season 2 (YouTube) Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome (Science Advances) Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID) Parasitic Uganda launches largest malaria vaccine introduction to date(WHO: Uganda) Long-term follow-up of individuals with Chagas disease treated with posaconazole and benznidazole in a non-endemic region(CMI: Clinical Microbiology and Infection) Miscellaneous Monoclonal Antibodies From Children With Acute Kawasaki Disease Identify a Common Antigenic Target in Fatal Cases Over 5 Decades (Laboratory Investigation) Screwworm Cochliomyia hominivorax (Facebook) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #78 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/27/25 – 4/9/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Demise of the Milwaukee protocol for rabies (CID) A natural experiment on the effect of herpes zoster vaccination on dementia (Nature) Taking a shot at dementia(microbeTV: TWiV) Recommendations from the 10th European Conference on Infections in Leukaemia for the management of cytomegalovirusin patients after allogeneic haematopoietic cell transplantation and other T-cell-engaging therapies (LANCET: Infectious Diseases) Epstein-Barr virus exposure precedes Crohn`s disease development (Gastroenterology aga) Bacterial Blujepa (gepotidacin) approved by US FDA for treatment of uncomplicated urinary tract infections (uUTIs) in female adults and paediatric patients 12 years of age and older (GSK) GSK wins FDA nod for first oral UTI antibiotic in almost 30 years(BioSpace) Efficacy and safety of individualised versus standard 10-day antibiotic treatment in children with febrile urinary tract infection (INDI-UTI): a pragmatic, open-label, multicentre, randomised, controlled, non-inferiority trial in Denmark (LANCET: Infectious Diseases) Frequency and severity of Myasthenia Gravis exacerbations associated with the use of ciprofloxacin, levofloxacin, and azithromycin (Muscle & Nerve) The cost of blood cultures: a barrier to diagnosis in low-income and middle-income countries (LANCET: Microbe) Rethinking blood culture (LANCET: Microbe) Trends in Anaplasmosis Over the Past Decade: A Review of Clinical Features, Laboratory Data and Outcomes(CID) Fungal The Last of US Season 2 (YouTube) Cracks in the curriculum: the hidden deficiencies in fungal disease coverage in medical books (OFID) Kazachstania slooffiae fungemia: a case report and literature review on an emerging opportunistic pathogen in humans (OFID) Plasma microbial cell-free DNS metagenomic sequencing for diagnosis of invasive fungal diseases among high risk outpatient and inpatient immunocompromised hosts (CID) Parasitic Fatal Case of Splash Pad–Associated Naegleria fowleri Meningoencephalitis — Pulaski County, Arkansas, September 2023 (CDC: MMWR) Notes from the Field: Fatal Acanthamoeba Encephalitis in a patient who regularly used tap water in an electronic nasal irrigation device and a continuous positive airway pressure machine at home — new Mexico, 2023 (CDC: MMWR) Malaria (NEJM) Miscellaneous FDA grants marketing authorization of first home test for chlamydia, gonorrhea and trichomoniasis (FDA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #77 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13/25 – 3/26/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Food is medicine for human immunodeficiency virus: improved health and hospitalizations in the changing health through food support (chefs-hiv) pragmatic randomized trial (JID) The epidemiology and burden of human parainfluenza virus hospitalizations in u.s. children (Journal of the Pediatric Infectious Diseases Society) Bacterial Epidemiology and outcomes of bloodstream infections in patients in a burns intensive care unit: an eight-year retrospective study(OFID) Prophylactic vancomycin in the primary prevention of clostridium difficile in allogeneic stem cell transplant(Transplant Infectious Disease) Incidence of scrub typhus in rural south India (NEJM) Antibiotic treatment for 7 versus 14 days in patients with bloodstream infections(NEJM) Blood Culture–Negative Endocarditis(Journal of the American Heart Association) Brucella suis Infection in Cardiac Implantable Device of Man Exposed to Feral Swine Meat, Florida, USA (CDC Emerging Infectious Diseases) Hyperbilirubinemia at hospitalization predicts nosocomial infection in decompensated cirrhosis (Hepatology Communicatons) Fungal The Last of US Season 2 (YouTube) Fungal Infections in People Who Use Drugs (OFID) IDSA 2025 guideline update on the treatment of asymptomatic histoplasma pulmonary nodules (histoplasmomas) and mild or moderate acute pulmonary histoplasmosis in adults, children, and pregnant people(IDSA: Infectisous Disease Society of America) Changing trends in the sources and volumes of clinical cultures with Candida auris at a large health system, 2019-2023 (American Journal of Infection Control) Diagnostic test accuracy of the Fungitell serum (1→3)-β-D-glucan assay for the diagnosis of Pneumocystis jirovecii pneumonia: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Parasitic Impact of Strongyloides stercoralis Coinfection on Disease Severity and Treatment Outcomes in Pulmonary Tuberculosis (OFID) Hematology thin smears perform equally to parasitology thick and thin blood smears for the diagnosis of Plasmodium and Babesia infections in a low prevalence setting (Journal of Clinical Microbiology) Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe — United States, August 2024 (CDC: MMWR) Miscellaneous The history of phage therapy LANCET: Infectious Diseases) Silence=death redux: infectious diseases, public health, and the imperative to resist (CID) Silence = Death, 1990(David Wojnarowicz Foundation) SILENCE=DEATH (B200KLYN Museaum) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #76 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/27/25 – 3/12/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Trends in respiratory pathogen testing at us children's hospitals (JAMA Network) Changes in respiratory viral testing before and after the covid-19 pandemic(JAMA Network) Expanding measles outbreak in the United States and guidance for the upcoming travel season (CDC Emergerncy Preparedness and Response) Measles cases and outbreaks (CDC Measles (Rubeola)) Facts and myths about measles (LANCET: Infectious Diseases) Protective effects of recombinant zoster vaccine and antiviral therapy against cardiovascular disease following herpes zoster infection (JID) Chikungunya vaccine information for healthcare providers (CDC Chikungunya Virus) Factors to assess when considering use of chikungunya vaccine(CDC) Bacterial Should patients hospitalized forcommunity-acquired pneumonia be treated with additional antimicrobial agents directed against anaerobes? (American Journal of Therapeutics) Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy(Blood) Effectiveness of ampicillin/sulbactam versus ceftriaxone for the initial treatment of community-acquired pneumonia in older adults: a target trial emulation study(OFID) Male-partner treatment to prevent recurrence of bacterial vaginosis(NEJM) Fungal The Last of US Season 2 (YouTube) Activity of rezafungin against echinocandin non–wild type candida glabrata clinical isolates from a global surveillance program (OFID) Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study  (Intensive Care Medicine) Parasitic Human alveolar echinococcosis – global, regional and national annual incidence and prevalence rates (CMI: Clinical Microbiology and Infection) Dust to Diagnosis – with MSGERC (FEBRILE) The clinical picture caused by Fasciola gigantica: Analysis of 3,250 patients along the 1995–2019 countrywide spread in Vietnam (OFID) Miscellaneous Reprint of: From medical editors: a call to the global infectious diseases and clinical microbiology community (CMI: Clinical Microbiology and Infection) A hot topic: A climate-focused track for infectious disease fellowship (OFID) Are we being gaslit? A primer for recognizing corporate jargon to overcome gaslighting for the infectious disease workforce (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #75 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/13/25 – 2/26/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral VIMKUNYA (FDA) Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19(BMC Infectious Diseases) Measles (Texas Health and Human Services) 2025 Measles outbreak guidelines (New Mexico Health) BTN: Beyond the Noise with Paul Offit (microbeTV) Rubeola response (febrile) Timing of influenza antiviral therapy and risk of death in adults hospitalized with influenza-associated pneumonia, influenza hospitalization surveillance network (FluSurv-NET), 2012–2019 (CID) Mother-child dyads living with HIV in the Western Cape, South Africa: undetectable = undetectable? (Journal of the International AIDS Society) Early impacts of the PEPFAR stop-work order: a rapid assessment(Journal of the International AIDS Society) Prevalence, clinical management, and outcomes of adults hospitalised with endemic arbovirus illness in southeast Europe (MERMAIDS-ARBO): a prospective observational study (LANCET: Infectious Diseases) Bacterial Effects of extended anaerobic antibiotic coverage on anaerobic bloodstream infection: A multisite retrospective stud (International Journal of Infectious Diseases) The effectiveness of newer Beta-Lactams for the treatment of antimicrobial-resistant gram-negative meningitis (CID) Treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children: a aeta-analysis of macrolides versus tetracycline (The Pediatric Infectious Disease Journal) Fungal The Last of US Season 2 (YouTube) Concordance of noninvasive plasma cell-free DNA With invasive diagnostics for diagnosis of invasive fungal disease (CID) Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit(Intensive Care Medicine) Parasitic Epidemiologic Investigation of Protozoa and soil-transmitted helminths in Starr County, Texas (American J Trop Med and Hyg) Post-artesunate delayed hemolysis in African children with severe malaria: incidence, medical impact and prevention (CID) Miscellaneous Telehealth (Medicare.gov) Public comment: IDSA guideline on management and treatment of complicated urinary tract infections (IDSA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #74 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/30/25 – 2/12/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Global Impact of mass vaccination campaigns on circulating type 2 vaccine-derived poliovirus outbreaks (JID) Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19 (BMC Infectious Diseases) Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID) Bacterial Predicting benefit from adjuvant therapy with corticosteroids in community-acquired pneumonia (LANCET Respiratory Medicine) Rethinking antibiotic prophylaxis for spontaneous bacterial peritonitis in patients with cirrhosis (CID) Determining the optimal antibiotic duration for skin and soft tissue infections (Current Opinion in Infectious Diseases) The stealth and potentially fatal nature of Kingella kingae outbreaks in daycare facilities (OFID) Piperacillin/tazobactam vs. cefepime or carbapenems for the treatment of bloodstream infections due to bacteria producing chromosomal AmpC beta-lactamase (Infection) Is systemic dissemination of BCG following neonatal vaccination required for protection against Mycobacterium tuberculosis? (JID) Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort study (eClinical Medicine) Fungal The Last of US Season 2 (YouTube) Developing mRNA lipid nanoparticle vaccine effective for cryptococcosisin a murine model (Vaccines) The araneopathogenic genus Gibellula (Cordycipitaceae: Hypocreales) in the British Isles, including a new zombie species on orb-weaving cave spiders (Metainae: Tetragnathidae) (Fungal Systematics and Evolution) Sensitivity of Coccidioides serologic tests among culture-proven coccidioidomycosis patients with hematological malignancy compared to a matched immunocompetent cohort (Medical Mycology) Parasitic New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases) Miscellaneous Remote practice of infectious diseases through telemedicine (OFID) Telemedicine offers solutions for the rural disparities in infectious disease (ID) care delivery (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #73 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/16/25 – 1/29/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation (Gastroenterology) Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients (Nature Communications) Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology (PLoS Neglected Tropical Diseases) Bacterial Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis (NEJM) Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria (American Journal of Infection Control) Identification of the skip phenomenon among patients With Staphylococcus lugdunensis infective endocarditis (OFID) Emergence of infective endocarditis due to Serratia spp. (OFID) Reduction of vancomycin-associated acute kidney injury with montelukast (JID) Fungal The Last of US Season 2 (YouTube) Pulmonary co-infection of Pneumocystis jirovecii and Aspergillus species (OFID) Impact of fluconazoleon outcomes of patients with primary pulmonary coccidioidomycosis (CID) Parasitic Comparative outcomes of Babesiosis in immunocompromised and non-immunocompromised hosts (CID) Miscellaneous Hidradenitis suppurativa (LANCET) A severe case associated with mixed infections of Pasteurella multocida, Bacteroides pyogenes and Fusobacterium necrophorum due to a snow leopard bite (CMI: Clinical Microbiology and Infection) INSIDE-OUT: Introduction of speakers at IDWeek events (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #72 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/2/25 – 1/15/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Human infection with a novel tickborne Orthonairovirus species in China(NEJM) Antiviral medications for treatment ofnonsevere influenza(JAMA Network: JAMA Internal Medicine)  Xofluza (GoodRx) NoroSTATData Table (CDC Norovirus) The discovery of the 27-nm Norwalk virus: an historic perspective (JID) Why the “Ferrari of viruses” is surging through the northern hemisphere (Science) Bacterial Beta-lactams toxicity in the intensive care unit: an underestimatedcollateral damage? (Microorganims) What is the most effective antibiotic monotherapy for severe Pseudomonas aeruginosa infection? (CMI: Clinical Microbiology and Infection) Doxycycline postexposure prophylaxis and bacterial sexually tansmitted infections among individuals using HIV preexposure prophylaxis(JAMA Network: JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Epidemiology and prognostic factors associated with mold-positive blood cultures: 10-year data From a french prospective surveillance program (2012–2022) (CID) Parasitic Safety and efficacy of immunization with a late-liver-stage attenuated malaria parasite (NEJM) Dr. Glaucomflecken explains: late-liver-stage attenuated malaria vaccine (YouTube) Dr. Glaucomflecken X NEJM (YouTube) Albendazole–ivermectin co-formulation for the treatment of Trichuris trichiura and other soil-transmitted helminths: a randomised phase 2/3 trial (LANCET: Infectious Diseases) Miscellaneous A comparison of peripherally insertedcentral catheter materials(NEJM) Considering Islamic frameworks to infectious disease prevention (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #71 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/19/24 – 1/1/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Routine detection of viruses through metagenomics: where do we stand? (ASTMH) Rapid selection of HIV-2 capsid mutations in salvage therapy with Lenacapavir-containing regime (CID) Bacterial Ancient genomes reveal a deep history of treponemal disease in the Americas (Nature) The utility of Interferon-γ release assays in the diagnosis of tuberculosis in patients With cancer(Transplant Infectious Disease) A meta-analysis of Levofloxacin for contacts of multidrug-resistant tuberculosis (NEJM Evidence) Tularemia— United States, 2011–2022 (CDC: MMWR) Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection (JID) Fungal The Last of US Season 2 (YouTube) Candida albicans recovered from persistent candidemia exhibit enhanced virulence traits (JID) Mapping the geographic distribution of dimorphic mycoses using a U.S. commercial insurance database (OFID) Comparative efficacy and safety of treatment regimens for Pneumocystis jirovecii pneumonia in people living with HIV – A systematic review and network meta-analysis of randomized controlled trials (CMI: Clinical Microbiology and Infection) Outbreak of Blastomycosis Among Paper Mill Workers — Michigan, November 2022–May 2023 (CDC: MMWR) Parasitic Acanthamoeba Infection in a hematopoietic cell transplant recipient: challenges in diagnosis, management, and source identification (Transplant Infectious Disease) Congenital toxoplasmosis: Fewer clinical signs at 3 years of age over the last 15 years but stable risk of materno-fetal transmission (CID) Miscellaneous Detection of prions in wild pigs (Sus scrofa) from areas with reported chronic wasting disease cases, United States (CDC Emerging Infectious Diseases) Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia (JID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #70 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/5/24 – 12/18/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epidemiology of Dengue— Puerto Rico, 2010–2024(CDC MMWR) Takeda Announces Voluntary Withdrawal of U.S. Biologics License Application (BLA) for Dengue Vaccine Candidate TAK-003(Takeda)  Global health and economic burden of chikungunya from 2011 to 2020 (BMJ Global Health) Bacterial Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis (JAMA Network) Say it ain't Steno: a microbiology nudge comment leads to less treatment of Stenotrophomonas maltophilia respiratory colonization(Infection Control & Hospital Epidemiology) Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults(JAMA Network) Epidemiology and Outcomes of Antibiotic De-escalation in Patients with Suspected Sepsis in US Hospitals (CID) Effectiveness of ceftazidime–avibactam versus ceftolozane–tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study (LANCET Infectious Diseases) Bedaquiline Monotherapy for Multibacillary Leprosy (NEJM) Fungal The Last of US Season 2 (YouTube) Histoplasmosis Associated With Bat Guano Exposure in Cannabis Grower (OFID) Parasitic TWiV 1175: A hitchiker's guide to virology(microbeTV) Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts (Nature Microbiology) Neurocysticercosis school outbreak in Belgium (LANCET) Miscellaneous Maintenance of Certification: Is a Knowledge-Based Assessment Really Necessary? (CID) Living happily ever after? The hidden health risks of Disney princesses (BMJ) How to transport a polar bear, and other idiosyncrasies in providing emergency medical services in the Arctic (BMJ) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #69 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/21 – 12/4/24. Host: Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Antiretroviral Drugs for Treatment and Prevention of HIV in Adults(JAMA Network) Human Parvovirus B19 Infections Among Pregnant Persons — Minnesota, January–September 2024 (CDC MMWR) Maribavir for refractory cytomegalovirus infection (with or without resistance) in solid organ transplant recipients (Journal of Heart and Lung Transplantation) Bacterial Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of InvasiveGroup A Streptococci Infection (CID) Resurgence of pediatric Mycoplasma pneumoniae infections in Southeast Texas, Nov 2023-June 2024 (Journal of Pediatrics Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Alternative Pneumocystis Pneumonia Prophylaxis in Solid Organ Transplants(Transplant Infectious Disease) Mortality in chronic pulmonary aspergillosis: a systematic review and individual patient data meta-analysis (LANCET: Infectious Diseases) Parasitic Waterborne Disease Outbreaks Associated with Splash Pads — United States, 1997–2022  (CDC MMWR) Miscellaneous Skin Color Representation in Infectious Disease Textbooks (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #68 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 11/7 – 11/20/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Comparative Emergence of Maribavir and Ganciclovir Resistance in a Randomized Phase 3 Clinical Trial for Treatment of Cytomegalovirus Infection (JID) Yellow fever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis (LANCET Microbe) Serological evidence of natural exposure to rabies in rural populations in Gabon (PLoS Neglecgted Tropical Diseases) Bacterial Azithromycin Exposure in a 10-Day Window of Myocardial Infarction and Short- and Long-Term Outcomes (JACC Advances) Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (NEJM) The Long and Winding Road: Three-year Mortality Following Prescription of Multi-drug Antibiotic Treatment for Mycobacterium avium complex Pulmonary Disease in United States Medicare Beneficiaries with Bronchiectasis (OFID) Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis (CID) Carbapenem-resistant Enterobacteriales in solid organ transplant recipients (American Journal of Transplantation) Fungal The Last of US Season 2 (YouTube) Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors(PLoS Pathogens) Diagnostic Test Accuracy of the Fungitell Serum (1→3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jirovecii Pneumonia: A Systematic Review and Meta-Analysis (CMI: Clinical Microbiology and Infection) Do patients with candidemia need an ophthalmologic examination? (OFID) Parasitic Progress Toward Global Dracunculiasis (Guinea Worm Disease) Eradication (CDC MMWR) The gut microbiota is essential for Trichinella spiralis—evoked suppression of colitis (PLoS Neglected Tropical Diseases) Symptomatic Entamoeba dispar Infections Among Men Who Have Sex With Men, New York City, 2018control (OFID) Angiostrongylus cantonensis Meningoencephalitis in Three Pediatric Patients in Florida, USA (Journal of the Pediatric Infectious Diseases Society) Miscellaneous  Snake phobia among the general population of Tamil Nadu, India(PLoS Neglected Tropical Diseases) Remote Practice of Infectious Diseases Through Telemedicine: Improving Access for Patients and Appeal for Physicians (OFID) Gauging Medical Students' Interests in Infectious Diseases (CID) Shaping the Future of Infectious Diseases: The Journey to Promote Value, Opportunity, and Positive Messaging (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #67 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/24 – 11/6/24. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia(Nature) Bacterial Implementation of a Pharmacist-Driven Vancomycin Area Under the Concentration-Time Curve Monitoring Program Using Bayesian Modeling in Outpatient Parenteral Antimicrobial Therapy (OFID) Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin (Nature) Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis(CID) Fungal The Last of US Season 2 (YouTube) Notes from the Field: Trichophyton mentagrophytes Genotype VII — New York City, April–July 2024 (CDC MMWR) Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients(Transplant Infectious Disease) Parasitic Outcomes of kidney transplant recipients exposed to Chagas disease under Benznidazole prophylaxis(Transplant Infectious Disease) Fake Aristotle Fakely Rails Against Fighting Inequality (Sententiae Antiquae) Need for a paradigm shift in soil-transmitted helminthiasis control (PLoS Neglected Tropical Diseases) Miscellaneous IDSA Advocacy Results in Big Win for ID in 2025 Final Medicare Rule (IDSA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice

On episode #66 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/8 – 10/23/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Prevalence of Human Papillomavirus (HPV) and HPV Type Distribution in Penile Samples in Young Men in Denmark: Results 10 Years After Implementation of a Girls-Only HPV Vaccination Program (JID) Primary Care Guidance for Providers of Care for Persons With Human Immunodeficiency Virus: 2024 Update by the HIV Medicine Association of the Infectious Diseases Society of America (CID) Bacterial Adjunctive linezolid versus clindamycin for toxin inhibition in β-lactam-treated patients with invasive group A streptococcal infections in 195 US hospitals from 2016 to 2021: a retrospective cohort study with target trial emulation (LANCET: Infectious Diseases) Time to turn off the toxins: adjuvant suppression of group A streptococcus (LANCET: Infectious Diseases) Comparing rates of recurrent infection for first occurrence of Clostridioides difficile between tapered oral vancomycin and standard vancomycin: a retrospective, propensity matched cohort study(Infection Control and Hospital Epidemiology) Evaluation of primary oral vancomycin prophylaxis against C. difficile infection during autologous stem cell transplantation (OFID) Oral Vancomycin to Prevent C. difficile in Stem Cell Transplant Recipients: The last frontier in antimicrobial prophylaxis (OFID) First Report of a Fatal Septicemia Case Caused by Vibrio metoecus: A Comprehensive Functional and Genomic Study (JID) Fungal The Last of US Season 2 (YouTube) A global chromoblastomycosis strategy and development of the global chromoblastomycosis working group(PLoS Neglected Tropical Diseases) Epidemiological and clinical features of a large blastomycosis outbreak at a paper mill in Michigan (CID) Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris? (PLoS Pathogens) Parasitic Beyond Human Babesiosis: Prevalence and Association of Babesia Coinfection with Mortality in the United States, 2015–2022: A Retrospective Cohort Study (OFID) New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases) Miscellaneous Social and Environmental Benefitsof Pediatric Infectious Disease Telemedicine (Journal of the Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #65 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/26 – 10/7/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Exploring viral respiratory coinfections: Shedding light on pathogen interactions (PLoS Pathogens) Bacterial ACG Clinical Guideline: Treatment of Helicobacter pylori Infection (American Journal of Gastroenterology) A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection (Science) The evidence base for the optimal antibiotic treatment duration of upper and lower respiratory tract infections: an umbrella review (LANCET: Infectious Diseases) Population Pharmacokinetic Modeling of Cefepime, Meropenem, and Piperacillin-Tazobactam in Patients With Cystic Fibrosis(JID) Establishment of Amblyomma maculatum Ticks and Rickettsia parkeri in the Northeastern United States (Emerging Infectious Diseases) DETICKT (DETICKT) Early Oral Step-Down Versus Continued Intravenous Antibiotic Treatment of Complicated Intra-Abdominal Infection(Surgical Infections) Fungal The Last of US Season 2 (YouTube) Candida auris: A focused review for emergency clinicians (American Journal of Emergency Medicine) Parasitic Ivermectin-based mass drug administration for scabies in northern India: a single-arm community intervention trial (OFID) Miscellaneous Out-BREAK! : An IDWeek 2023 escape room to break out of the educational mold (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #64 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/14 – 9/25/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Outcomes of Intravenous Immunoglobulin treatment of immunocompromised patients with viral respiratory infections (Annals of Allergy, Asthma & Immunology) Comparative Emergence of Maribavir and Ganciclovir Resistance for Treatment of Cytomegalovirus Infection (JID) Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA (LANCET Infectious Disease) Bacterial Determinant of 30-Day Mortality of Pulmonary Legionellosis (OFID) Donor-derived bartonellosis in Solid Organ Transplant recipients (American Journal of Transplantation) An Opt-Out Emergency Department Screening Intervention Leads to Major Increases in Diagnosis of Syphilis (OFID) Fungal The Last of US Season 2 (YouTube) Fungal disease week (CDC) Bridging Echinocandin with Azole antifungal Therapy On Prevention Of Invasive Candidiasis Post Lung Transplantation (OFID) Early Introductions of Candida auris Detected by Wastewater Surveillance, Utah, USA, 2022–2023 (Emerging Infectious Diseases) Parasitic Toxoplasma gondii Infection of Alzheimer's Disease Mice Reduces Brain Amyloid Density Globally and Regionally (JID) Miscellaneous Effect of Social Distancing Caused by Heavy Snowfall on Seasonal Influenza Epidemic in a Local Region in Japan (Pediatric Infectious Disease Journal) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #63 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/29/24 – 9/13/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Postacute Sequelae of COVID (PASC or Long COVID): An Evidenced-Based Approach (OFID) A New Orthonairovirus Associated with Human Febrile Illness (NEJM) Farmed fur animals harbour viruses with zoonotic spillover potential(Nature) A Cross-Sectional Evaluation of the Virtual Outpatient Management of People With Mpox (OFID) A randomized, placebo-controlled, dose-escalation phase I/II multicenter trial of low-dose cidofovir for BK polyomavirus nephropathy (Transplant Infectious Disease) A Decade of Chronic Norovirus Infection Surveillance at the NIH Clinical Research Center: Clinical Characteristics, Molecular Epidemiology, and Replication (JID) Bacterial FDA clears newLyme disease test (CIDRAP) Lyme ImmunoBlot Receives FDA Clearance(Accesswire) The Utilization Of Echocardiography In Children With Staphylococcus aureus Bacteremia (Journal of Pediatric Infectious Diseases Society) Duration of antibiotic therapy for multidrug resistant Pseudomonas aeruginosa pneumonia: is shorter truly better?(BMC Infectious Diseases) Short Versus Long Antibiotic Duration in Streptococcus pneumoniae Bacteremia (OFID) FDA Marketing Authorization Enables Increased Access to First Step of Syphilis Diagnosis FDA) Clinical impact of pleural fluid Streptococcus pneumoniae PCR testing in children with complicated pneumonia (CID) Duration of antibiotic therapy for multidrug resistant Pseudomonas aeruginosa pneumonia: is shorter truly better? (BMC Infectious Diseases) Short Versus Long Antibiotic Duration in Streptococcus pneumoniae Bacteremia (OFID) Fungal The Last of US Season 2 (YouTube) Incidence and risk factors for invasive fungal infections in patients initiating TNF-alpha inhibitors for inflammatory bowel disease and rheumatoid arthritis (CID) Parasitic Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice(Science Translational Medicine) Miscellaneous Successful Treatment of Refractory Cutaneous Protothecosis With MAT2203, an Oral Lipid Nanocrystal Formulation of Amphotericin B (OFID) The Impact of Infectious Diseases Scholarly Mentorship on Subsequent Infectious Disease Fellowship Application (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #62 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/15/24 – 8/28/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Clinician Specialty and HIV PrEP Prescription Reversals and abandonments (JAMA Network: JAMA Internal Medicine) The association between adherence to antiretroviral therapy and viral suppression under dolutegravir-based regimens (JIAS Journal of the International AIDS Society) Dexamethasone in adults with viral meningitis (CMI Clinical Microbiology and Infection) Oropouche Virus Disease Among U.S. Travelers — United States, 2024 (MMWR) Oropouche fever, the mysterious threat (LANCET: Infectious Diseases) Bacterial High rates of Non-susceptibility to common oral antibiotics in Streptococcus pneumoniae clinical isolates (OFID) New York State Department of Health Directs Providers to Discontinue Use of Ciprofloxacin to Prevent Meningococcal Disease Due to Increasing Antimicrobial Resistance (NY State: Department of Health) Tularemia Associated with Harbor Seal Necropsy — Kitsap County, Washington, October 2023 (MMWR) FDA Marketing Authorization Enables Increased Access to First Step of Syphilis Diagnosis (FDA) Clinical impact of pleural fluid Streptococcus pneumoniae PCR testing in children with complicated pneumonia (CID) The Role of the Gut, Urine and Vaginal Microbiome on the Pathogenesis of Urinary Tract Infection (OFID) Fungal The Last of US Season 2 (YouTube) Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan (LANCET Infectious disease) Parasitic Usefulness of real-time PCR for urogenital schistosomiasis in preschool children in Angola (PLoS Neglected Tropical Diseases) Helminth infection driven gastrointestinal hypermotility alterations in smooth muscle instead of enteric neurons (PLoS Pathogens) Die-off reaction of Demodex mites after treating demodicosis with oral ivermectin (JAAD case reports) Miscellaneous Prevalence of carbapenem-resistant gram negative bacteria among neonates suspected for sepsis in Africa (BMC Infectious Diseases) New era of targeted clinical guidelines: IDSA (CID) Defining the landscape of educational experiences in transplant infectious diseases (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #61 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/1/20 - 8/14/24.  Host: Daniel Griffin and Sara Dong  Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral nPEP quick guide (AIDS Education & Training Center Program) Coformulated Bictegravir/Emtricitabine/Tenofovir Alafenamide PREP after sexual assault (OFID) Adopting Early Testing for Perinatal Hepatitis C (Journal of Pediatric Infectious Diseases Society) Bacterial Lower Rates of Staphylococcus aureus Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis (OFID) Trimethoprim-Sulfamethoxazole for Staphylococcus Aureus Bacteremia Prophylaxis in Patients on Hemodialysis (OFID) Human monocytotropic ehrlichiosis(PLoS Neglected Tropical Diseases) Human granulocytotropic anaplasmosis (PLoS Neglected Tropical Diseases) Bifidobacterium and Lactobacillus Probiotics for Preterm Infants (JAMA Network: JAMA Pediatrics) Rapid Implementation of Blood Culture Stewardship (CID) BD BACTEC Blood Culture Bottle Shortage - (IDSA) Fungal The Last of US Season 2 (YouTube) Clinical characteristics and mortality risks among critically ill patients with culture-proven coccidioidomycosis(OFID) Poor Clinical and Microbiologic Outcomes in C. auris Bloodstream Infection (CID) Parasitic Soap is lethal for Schistosoma mansoni cercariae (PLoS Neglected Tropical Diseases) Treatment of uncomplicated hepatic cystic echinococcosis (Cochrane Library) Blood exposure to Babesia microti(Cambridge Core) Miscellaneous Absence of Cerebrospinal Fluid Pleocytosis in Encephalitis (CID) Encephalitis due to Infection with Normocellular Cerebrospinal Fluid (CID) Podoconiosis and mental health (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

On episode #60 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/18/20 – 7/31/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Olympics Swimming in the Seine (NYTimes) Viral Twice-Yearlylenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women (NEJM) Consensus definitions of Cytomegalovirus Infection and Disease in Transplant Patients (CID) The recombinant shingles vaccine is associated with lower risk of dementia (Nature Medicine) Association of the incidence of postherpetic neuralgia with early treatment intervention of herpes zoster (International Journal of Infectious Diseases) Bacterial Updated guidelines for antimicrobial resistant gram-negative infections (IDSA) Put the Vanc Down, Flip it and Reverse it: Comparison of vancomycin and daptomycin (OFID) Durations of antibiotic treatment for acute otitis media and variability in prescribed durations (Journal of Pediatric Infectious Diseases Society) Fungal Adjunctive single-dose liposomal amphotericin to prevent cryptococcal meningitis in people with human immunodeficiency virus (HIV)–associated cryptococcal antigenemia and low plasma cryptococcal antigen (CrAg) titers(CID) Stagonospora cutaneous infection in a kidney transplant recipient: First human case (Transplant Infectious Disease) European Study of cerebral aspergillosis treated with Isavuconazole: an EFISG study (CID) Parasitic Rollout of world's second malaria vaccine begins in Ivory Coast (Healio) Executive summary: Evaluation and management of delusional infestation(CID) Parasitic contamination of soil in the Southern United States (ASTMH) Miscellaneous The potential benefits of delaying seasonal influenza vaccine selections for the northern hemisphere: A retrospective modeling study in the United States (JID) Music is by Ronald Jenkees

On episode #59 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3/20 – 7/17/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral The potential interrelationship of coronary artery disease -herpes zoster (OFID) Bacterial Pharmacokinetics of intravenous antibiotics into the infected pleural space (Thorax) Are gas emissions from microbiology cultures significant contributes to global warming?(OFID) Is combination treatment of ampicillin and gentamicin right for Listeria monocytogenes infection (Infection) Screening organ donors and monitoring recipients for Bartonella quintana (OFID) Neglected Tropical Disease: Rocky Mountain spotted fever (PLoS Pathogen) Updated guidelines for antimicrobial resistant gram-negative infections (IDSA) Fungal Are fungal pathogenssmarter than we are? (microbeTV) What influences the waning of antibodies during cryptococcal meningitis? (JID) Parasitic Artificial Intelligence for filariasis diagnosis and monitoring (PLoS Neglected Tropical Diseases) Is artificial intelligence the end of filariasis? (PLoS Neglected Tropical Diseases Miscellaneous APACHE II severity of disease classification system (GlobalRxPh) Clinical practice guideline for complicated intra-abdominal infections (CID) Procalcitonin or C-reactive protein guided antimicrobial discontinuation to treat sepsis (Critical Care Medicine) The “plague” of plague for the Neolithic population (Nature) Music is by Ronald Jenkees

On episode #58 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/20 – 7/3/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Drink more coffee, reduces risk for SARS-C0V-2 infection (Cell & Bioscience) Cannabis, tobacco…smoking in general NOT good for preventing COVID-19 (JAMA Network OPEN) EBV and KSHV caused HIV associated cancers and lymphoproliferative disorders (Clinical Microbiology Reviews) Where in the CNS can dolutegravir, tenofovir, lamivudine and efavirenz be found? (JID) Therapeutic management of Varicella-Zoster virus meningitis (OFID) Bacterial Carbapenem use in extended-spectrum cephalosporin-resistant Enterobacterales infections (LANCET Infectious Diseases) IDSA guidelines (Columbia University) Guideline-Concordant Therapy for community-acquired pneumonia in the Hospitalized Population (OFID) Interpretive Criteria piperacillin/tazobactam susceptibility test for Enterobacterales (CID) FDA approval forCAPVAXIVE (FDA) 21 valent pneumococcal vaccine approved (Nature Reviews drug discovery) Antimicrobial resistant Staphylococcus aureus isolates (JAMA Network Open) Broad-spectrum antibiotic use for suspected community-onset sepsis (JAMA Network Open) Fungal The Last of Us ( Wikipedia) Challenges to vaccinating against coccidioidomycosis (OFID) Cryptococcosis: the story (OFID) Pneumocystis pneumonia: clinical spectrum, prophylaxis and delayed treatment (Intensive Care Medicine) Improve utilization of 1,3 β-D-glucan Testing(OFID) Music is by Ronald Jenkees

On episode #57 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/6 – 6/19/24. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Is letermovir or valganciclovir better to prevent CMV in kidney transplant recipients (JID) CMV antiviral therapy (GoodRx) Prevalence of and risk for CMV reactivation during COVID-19 pneumonia (PLoS One) Sofosbuvir off-label yellow fever treatment (OFID) Bacterial Preventing resistant gram negative bacteria through beta-lactam de-escalation in sepsis patients (CID) Competing risk analysis, survival analysis that aims to correctly estimate marginal probability of an event (Columbia University) Continuous or intermittent b-lactam infusion for critical sepsis (JAMA Network) Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock (JAMA Network) Phoenix sepsis score and risk in children with cancer (JAMA Network) New recognized spotted fever group Rickettsia in Northern California (Emerging Infectious Diseases) Screening for mycobacterium tuberculosis (Transplant Infectious Disease) Fungal Potential sexual transmission of Tinea pubogenitalis from TMWII (JAMA Dermatology) Household transmission of tinea infection (OFID) Drug-resistant oral candidiasis in HIV infected patients (BMC Infectious Disease) Parasitic Handheld digital microscope for rapid and comprehensive screening for urogenital and gastrointestinal schistosomiasis (American Journal of Tropical Medicine and Hygiene) Scorecard approach to eliminate onchocerciasis (Am J Trop Med Hyg) Miscellaneous Association between antibiotic receipt and provider rating (OFID) Infectious diseases and infection control prevention strategies when on ECMO (Perfusion) Music is by Ronald Jenkees

On episode #56 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/28 – 6/5/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Highly pathogenic H5N1 in US dairy cattle and 2 human cases (MMWR) Developing novel treatments for acute COVID-19 should address long COVID (JID) Reactivation of inherited HHV 6B in transplant recipient (JID) Bacterial Suppressive antibiotic therapy after DAIR for acute periprosthetic joint infections (OFID) Piperacillin-tazobactam vs cefepime for sepsis treatment (JAMA Internal Medicine) Are the new diagnostic algorithms for pulmonary tuberculosis more sensitive? (OFID) Social factors associated with congenital syphilis (CID) Oral vancomyin treatment influences Clostridioides difficile recurrence in patients on concurrent systemic antibiotics Association between infectious diseases consultation and morality in Gram negative infected patients (CID) Fungal Not washing your hands: fluconazole-resistant Candida parapsilosis epidemiology (OFID) Retrospective case series: how Candida auris blood infections effect left ventricular assist devices (OFID) Trichophyton indotineae: clinical course, suspectibility and genome sequence (JAMA Dermatology) Screening serum for cryptococcal antigen in liver transplant recipients (OFID) Parasitic US outbreak of human trichinellosis (MMWR) Plague-ing the Pawlowsky glands of human body lice and transmission by bite(PLoS Biology) Miscellaneous Global change drivers and risk of infectious disease (Nature) ID specialists should care about ventilation (CMI) Music is by Ronald Jenkees

On episode #55 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/9 – 5/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Highly pathogenic H5N1 in US dairy cattle and 2 human cases (MMWR) Developing novel treatments for acute COVID-19 should address long COVID (JID) Reactivation of inherited HHV 6B in transplant recipient (JID) Bacterial Suppressive antibiotic therapy after DAIRfor acute periprosthetic joint infections (OFID) Piperacillin-tazobactam vs cefepime for sepsis treatment (JAMA Internal Medicine) Are the new diagnostic algorithms for pulmonary tuberculosis more sensitive? (OFID) Social factors associated with congenital syphilis (CID) Oral vancomyin treatment influences Clostridioides difficile recurrence in patients on concurrent systemic antibiotics Association between infectious diseases consultation and morality in Gram negative infected patients (CID) Fungal Not washing your hands: fluconazole-resistant Candida parapsilosis epidemiology (OFID) Retrospective case series: how Candida auris blood infections effect left ventricular assist devices (OFID) Trichophyton indotineae: clinical course, suspectibility and genome sequence (JAMA Dermatology) Screening serum for cryptococcal antigen in liver transplant recipients (OFID) Parasitic US outbreak of human trichinellosis (MMWR) Plague-ing the Pawlowsky glands of human body lice and transmission by bite(PLoS Biology) Miscellaneous Global change drivers and risk of infectious disease (Nature) ID specialists should care about ventilation (CMI) Music is by Ronald Jenkees

On episode #54 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/25 – 5/8/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Dengue: mother and child (American Economic Journal) Dairy farm worker and high path avian influenza A (H5N1) (NEJM) Respiratory virus pre and post transplant outcomes in children (CID) Bictegravir for HIV suppression during pregnancy (CID) Bacterial Group A Streptococcus pharyngitis: rapid diagnostic & antimicrobial stewardship (Pediatric ID Consult) Scrub typhus : Masquerade of disaster (OFID) One size fits all for UTI predictions? (CID) Infections of durable and acute mechanical circulatory support devices (Journal of Heart and Lung Transplantation) Fungal Crypto hosts for cryptococcal disease (NEJM) Parasitic Sampling for cutaneous Leishmaniasis (OFID) Skin monoclonal anti-Malaria antibody therapy (NEJM) Miscellaneous Origin of antimicrobial therapy (CID) Microneedle patches for MR (measles and rubella) vaccination (LANCET) Music is by Ronald Jenkees

On episode #53 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/11 – 4/24/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Reasons for what we do for routine respiratory pathogens (Journal of Hospital Medicine) Acute cardiac events due to RSV infection (JAMA Internal Medicine) Antiretroviral drugs and weight change (CID) What do antibiotics do for acute lower respiratory tract infection (Journal of General Internal Medicine) Guidelines for managing BK polyomavirus in kidney transplantation (Transplant) Bacterial Understanding Yersinia enterocolitica epidemiology(OFID) Medtronic duet external ventricular drain infections(MMWR) Who is more expensive daptomycin or vancomycin (OFID) Fungal Coccidioidomycosis related hospital visits (Emerging Infectious Diseases) Parasitic Leech in oropharynx of a 2-year old leads to anemia (AJTMH) The real use of ivermectin: treatment of strongyloidiasis (AJTHM) Miscellaneous Sporadic CJD in hunters? (Neurology) Where are all the infectious disease doctors? (OFID) Not interested in infectious diseases? Seriously! (CID) Music is by Ronald Jenkees

On episode #51 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/28 – 4/10/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Winter vomiting disease (Open Forum Inf Dis) Ceftriaxone-Resistant Gonorrhea — China, 2022 (MMWR) Give me five days of antibiotics (JPIDS) Where did this come from (JPIDS) Differentiating cellulitis from pseudocellulitis (JAMA Derm) FLIR One Pro Neonatal Elizabethkingia anophelis meningitis from the water reservoir of automated infant milk dispenser (Eurosurveill) d-Mannose for Prevention of Recurrent UTI Among Women (JAMA Int Med) Oral vaccine for UTI potential alternative to antibiotics (Eurek!Alert) Oral vaccine for UTI trials BJUI one and BJUI two and NEJM NLRP3 inflammasome activation and type I interferon signaling predispose to necrotizing fasciitis (Cell Rep Med) Candida deep sternal wound infections: a consequence of antibiotic use? (OFID) Candida auris in US Correctional Facilities (Emerg Inf Dis) Scedosporiosis and lomentosporiosis: difficult-to-treat rare mold infections (Clin Micr Rev) Meeting the consultation surge (OFID) Music is by Ronald Jenkees

On episode #51 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13 – 3/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral The oral antiviral obeldesivir protects NHPs against Sudan ebolavirus (Science) Monoclonal antibody therapy to treat Ebola virus disease (Curr Opinion Vir) Opinion of anti-Sudan ebolavirus antiviral therapy (Science) Management of norovirus in solid organ and hematopoietic stem cell transplants (Transplant ID) Bacterial Bacteremia from urinary source in hospitalized adults with asymptomatic bacteriuria?(JAMA) UTI research reference standards (Lancet Infectious Diseases) Aspiration pneumonia (CHEST) Household transmission of Strep A (JID) Antimicrobial dosing recommendations for obese patients (Antimicrobial Agents and Chemotherapy) Syphilis testing (MMWR) Predictors of morality from streptococcal bacteremia (CID) Fungal Invasive candidiasis (Nat Rev Disease Primer) Climate change and natural disasters impact on fungal infections (Lancet Microbe) Parasitic Nasal flushing and Acanthamoeba infection (Emerging Infectious Diseases) Miscellaneous Vaccination guidelines for adults with cancer (Journal of Clinical Oncology) Do multiplexed molecular diagnostic tools impact treatment for children with acute gastroenteritis? (CID) Music is by Ronald Jenkees

On episode #50 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/28 – 3/12/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Measles….and more measles (JPIDS) Need for new mumps vaccine (PIDJ) Cabotegravir and rilpivirine for those infected with HIV (JAMA) Genetic susceptibility to astrovirus diarrhea (OFID) 10 years after hepatitis E vaccination (Lancet) Tecovirimat for improvement of mpox symptoms (OFID) Bacterial Clinical care for tick-borne disease affected by paging clinicians serological results (AJTHM) Metabolomics of nontuberculous mycobacterial pulmonary disease (JID) Predicting risk of infectious endocarditis in those with Staphylococus aureus bacteraemis (JID) Fungal Response to invasive pulmonary aspergillosis (OFID) Parasitic Postsurgical outcomes due to hippocampal sclerosis (AJTHM) Miscellaneous What does the neutrophil to lymphocyte ratio mean in elderly with severe sepsis and diabetes mellitus (BMC Geriatrics) Impact of learning from Febrile podcast for infectious diseases (OFID) Music is by Ronald Jenkees

On episode #49 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/14 – 2/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral HIV Cure?  (NEJM) The effects of HIV-1 antigen-expanded specific T-Cell therapy and vorinostat on persistent infection (JID) The burden of HMPV and influenza associated hospitalizations in adults (JID) Bacterial Length of antibiotic therapy among the hospitalized with uncomplicated pneumonia (Infection Control & Hospital Epidemiology) Guideline on fecal microbiota–vased therapies for some gastrointestinal diseases (Gastroenterology) Guideline on fecal microbiota–based therapies for recurrent C diff (CIDRAP) Reduced vancomycin susceptibility in Clostridioides difficile (CID) Fungal Histoplasmosisin non-HIV population (OFID) Parasitic Plasmodium falciparum under the host's Immune radar(JID) Did you hear Artemether-lumefantrine is recommended for uncomplicate malaria CID) Miscellaneous Uncompensated work in academic infectious diseases, seriously? (CID) Invasive mosquito Anopheles stephensi, Ghana (Emerging Infectious Diseases) Music is by Ronald Jenkees

On episode #48 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/31 – 2/13/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Infectious attenuated tetravalent Butanatan-Dengue vaccine (NEJM) Kids with severe disease following first and second dengue virus infection (Nature) Oropouche fever outbreak in Latin America (Lancet Infectious Diseases) CMV mRNA vaccine knocks out gB/MF59 vaccine (JID) Acyuclovir-resistant mucocutaneous HSV in immunocompromised patients (OFID) Bacterial Dalbavancin for vertebral osteomyelitis (OFID) Severe vibrio vulnificus infections (MMWR) Demystifying UTIs in the era of antibiotic resistance (PLoS Pathogens) Syphilis testing recommendations (MMWR) Doxycycline vs azithromycin for scrub typhus (BMC Infectious Diseases) REALLY drug resistant Pseudomonas aeruginosa outbreak(CID) Fungal SUBA or conventional itraconazole for treatment of endemic mycoses (OFID) Fluconazole resistant Candida (CDC) Are you in the hospital too long after being treated with echinocandin for your Candidemia or invasive Candidiasis (OFID) Nasopharyngeal swab or lower respiratory tract specimen for Pneumocystis jirovecii diagnosis (OFID) Global guideline for cryptococcosis diagnosis and management (Lancet Infectious Disease) Parasitic Toxoplasma IgG positivity associates with increase mortality (AJTMH) Miscellaneous How well did infectious diseases fellows match (JID) Back to the future of the physician-scientist in infectious diseases (JID) Full or not infectious disease training (JID) Music is by Ronald Jenkees

On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/18 – 1/31/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Reinfection by Zika via genome diversity and antibody response (EID-Emerging Infectious Disease) People with HIV should breast/chest feed (CID) Norovirus GII in the water (PLoS Water) Herpes zoster and duloxetine premedication for neuralgia (CID) Bacterial SABATO: early oral switch trial (Lancet) Guideline for concordant antibiotic therapy to treat community-acquired pneumonia (Chest) Ceftriaxon with or without Nafcillin/Oxacillin for MSSA treatment (OFID) Ceftriaxone to prevent ventilator-associated pneumonia trial (Lancet) Azithromycin part of routine well-infant visits (NEJM) Burkholderia pseudomallei in Mississippi(NEJM) Cefiderocol red wine urine syndrome in children (Pediatric Infectious Disease Journal) Fungal InsuranceClaims equals blastomycosis Incidence (EID) Antimicrobial stewardship for coccidioidomycosis in endemic region (OFID) Endemic mycosesafter solid organ transplantation (OFID) Parasitic Headbobbing trematoda (CMI) Miscellaneous Suspected hemophagocytic lymphohistiocytosis (JPIDS) BioFire FilmArray for real-life assessment of hospitalized respiratory illness (JID) Clinical microbiology conferences gender and geography (Lancet) Is the toilet really the greatest sanitation invention? (AJICJ) Music is by Ronald Jenkees

On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/4 – 1/17/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Comparing the performance of three models incorporating weather data to forecast dengue epidemics (JID) Elucidating the impacts of climate on dengue transmission through mathematical models (JID) Infants receiving a single dose of nirsevimab to prevent RSV do not have evidence of enhanced disease in their second RSV season (JPIDS) Patient perspectives on solid organ transplantation from donors with hepatitis C viremia to recipients without hepatitis C viremia (OFID) Oral Beta-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for definitive treatment of uncomplicated Escherichia coli or Klebsiella species bacteremia from a urinary source (OFID) Discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus in a pediatric healthcare system (JPIDS) Oral linezolid compared with benzathine PCN G for treatment of early syphilis in adults (The Lancet) Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections (OFID) The Xpert MTB/RIF cycle threshold value predicts M.tuberculosis transmission to close contacts (CID) Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (The Lancet) Oral antibiotics for treatment of Gram negative bacteremia in solid organ transplant recipients (CID) Dematiaceous fungal keratitis with tentacles mimicking Pythium Keratitis (Jama) Verification, analytical sensitivity, cost-effectiveness, and comparison of four Candida auris screening methods (OFID) Tafenoquine-Atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis (JID) Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID) Understanding parental leave policies in ID fellowship (OFID) What's hot this year in ID clinical science (CID) Music is by Ronald Jenkees

On episode #45 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/20/23 – 1/3/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Notes coming soon Bacterial Change in oral PrEP affect kidney function (OFID) Preventing STIs in women (NEJM) Revising antibiotic and STI trials (NEJM) Treatment for pediatric febrile UTIs (Pediatrics) Burkholderia pseudomallei in Mississippi (NEJM) Acute kidney injury and gentamicin treatment for endocarditis (JACAMR) Pacemakers for Lyme disease patients (OFID) Pseudomonas aeruginosa update  and must have references (CMI) Fungal Definining optimal dose liposomal amphotericin B for Candida auris (JID) Cryptococcus neoformans and HIV serology (OFID) Global emergence of Candida auris (OFID) Novel anti-cancer therapeutics and fungal biology (PLoS Pathogens) Parasitic Second malaria vaccine prequalified (WHO) Seasonal vaccination against malaria in children (Lancet ID) Toxoplasma gondii treatement guidelines for patients with haematological malignancies (Lancet ID) Miscellaneous Eye infection review (NEJM) Diagnosing children with gastroenteritis using molecular testing (CID) Are hospital coffee machines pathogenic (BMJ) Putting down the fluoroquinolone (CID) Music is by Ronald Jenkees

On episode #44 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 12/8 – 12/20/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Mpox and chickenpox co-infection (J Inf Dis) Corticosteroids for postherpetic neuralgia (Coch Data Syst Rev) Dengue incidence and mortality in Bangladesh (J Inf Dis) ACORN trial vancomycin and piperacillin-tazobactam (Open For Inf Dis) Models for infection risk in children with cancer (J Clin Oncol) Salmonella outbreak from cantaloupes (CDC) Pediatric antimicrobial stewardship programs ( Ped Inf Dis Soc) MRSA nasal swab PCR assay (J Ped Inf Dis Soc) Invasive meningococcal disease (Open For Inf Dis) Probiotics for recurrent UTI (Clin Inf Dis) Preservation fluid contamination and kidney transplant patients (Transpl Inf Dis) Mechanism of zinc prevention of candidiasis (Sci Transl Med) Risk factors for invasive fungal infection (Open For Inf Dis) Genetic variants associated with S. mansoni worm burden (PLoS NTD) Chagas disease GI manifestations (Am J Trop Med Hyg) Wolbachia in Aedes aegypti in Colombia (PLoS NTD) Music is by Ronald Jenkees

On episode #43 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/22 – 12/06/23. Host: Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Treatment for first cytomegalovirus infection post-hematopoietic cell transplant (CID) Mortality among children aged

On episode #42 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/09 – 11/21/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Progress toward measles elimination (CDC) Slaying the troll of transplantation (TID) Association between the neutrophil-to-lymphocyte ratio and adverse outcomes in children aged

On episode #41 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/26 - 11/08/23.   Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS Become a patron of Puscast! Links for this episode Intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong (JID) Efficacy and safety of corticosteroid therapy for community-acquired pneumonia (CID) Hydrocortisone in severe community-acquired pneumonia (NEJM) Early oral antibiotic switch in Staphylococcus aureus bacteraemia (CID) Outbreak of invasive Group A Streptococcus in children (PIDS) Inhaled amikacin to prevent ventilator-associated pneumonia (NEJM) Assessing risk for complications in acute hematogenous osteomyelitis in children (JPIDS) Empirical antibiotic therapy in diabetic foot ulcer infection increases hospitalization(OFID) 2023 guideline on diagnosis and management of acute bacterial arthritis in pediatrics (JPIDS) Natural history of antibiotic-treated lower limb cellulitis (OFID) Missed opportunities for preventing congenital syphilis (CDC) Diverse clinical manifestations and challenges of mucormycosis (OFID) Malaria (The Lancet) Clinical characteristics and outcomes of Chagas disease (AJTMH)  Direct gloving vs hand hygiene before donning gloves in adherence to hospital infection control practices (JAMA) How I approach diarrhea in hematological transplant patients (TID) Innovating pediatric infectious diseases recruitment and training (JPIDS) Music is by Ronald Jenkees

On episode #40 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/13 – 10/25/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary HIV infection (CID) Dolutegravir monotherapy possibly boosted by highly active natural immunity (CID) Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination (The Lancet) Linezolid population pharmacokinetic model in plasma and cerebrospinal fluid among patients with tuberculosis meningitis (JID) Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults (NEJM) Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection (JAMA) Acute kidney injury with empirical antibiotics for sepsis (JAMA) Mycobacterium abscessus outbreak related to contaminated water among  ventilator-dependent residents of a pediatric facility (CDC) Trial of Vancomycin and Cefazolin as surgical prophylaxis in arthroplasty (NEJM) Trimethoprim-sulfamethoxazole significantly reduces the risk of nocardiosis in solid organ transplant recipients (CMI) Risk of hematologic cancers among individuals tested for Borrelia burgdorferi antibodies, and Borrelia burgdorferi seropositive individuals (CMI) In vitro susceptibility patterns for slowly growing non-tuberculous mycobacteria (JAC) Real-world use of mold-active triazole prophylaxis in the prevention of invasive fungal diseases (OFID) Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 (INI) Real-time dermoscopy of numerous mites crawling on the crusted scabies (CMI) The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis (The Lancet) Decolonization in nursing homes to prevent infection and hospitalization (NEJM) Can chatbot artificial intelligence replace ID physicians in the management of bloodstream infections (CID) Nasal iodophor antiseptic vs nasal mupirocin antibiotic in the setting of chlorhexidine bathing to prevent infections in ICUs (JAMA) FDA Approves PENBRAYATM for the prevention of the five most common serogroups causing meningococcal disease in adolescents (Pfizer) Music is by Ronald Jenkees

On episode #39 of the Infectious Disease Puscast, recorded at IDWeek in Boston, Daniel and special host Priya Kodiyanplakkal review the infectious disease literature for the weeks of 9/27 – 10/12/23. Host: Daniel Griffin and Priya Kodiyanplakkal Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Survival from rabies in a young child from India (AJTMH) The perils of overly-sensitive viral load testing for persons living with HIV (OFID) Letermovir vs Valganciclovir for prophylaxis of Cytomegalovirus in high-risk kidney transplant recipients (JAMA) Frailty and survival in the 1918 influenza pandemic (PNAS) Adverse pregnancy outcomes among HIV-infected Women taking isoniazid preventive therapy during the first trimester (CID) Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia (NEJM) Real-world application of oral therapy for infective endocarditis (CID) Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections (The Lancet) Information delay of significant bloodstream isolates and patient mortality (CID) Critical appraisal beyond clinical guidelines for intra-abdominal candidiasis (CC) Update on outbreak of fungal meningitis among Americans who received epidural anesthesia at clinics in Mexico Increasing prevalence of artemisinin-resistant HRP2-negative malaria in Eritrea (NEJM) Gender differences in psychosocial determinants of hand hygiene among physicians (ICHE) Music is by Ronald Jenkees