Podcasts about safety assessment

In this episode of The Safety Guru, we welcome Dr. Nektarios Karanikas, Associate Professor in the Health, Safety, and Environment discipline at Queensland University of Technology. He shares enlightening insights from his recently published research on "Redefining Health, Risk, and Safety" and explores their interconnectedness. Dr. Karanikas emphasizes the importance of leaders recognizing that safety is a duty, actively engaging with safety professionals, and listening to foster a culture of safety within organizations. Don't miss this opportunity to gain valuable perspectives from Dr. Karanikas—listen now! About the Guest: Dr. Nektarios Karanikas is an Associate Professor in the Health, Safety, and Environment discipline at Queensland University of Technology (AU). He holds an MSc in Human Factors and Safety Assessment from Cranfield University (UK) and a PhD in Safety and Quality Management from Middlesex University (UK). Nektarios has 19 years of experience in the Hellenic Air Force, specializing in safety, quality management, and accident investigations, and served as a lecturer in safety and human factors. He has published two edited books and numerous peer-reviewed articles and has presented at over 100 events. Nektarios is also an active volunteer in various scientific and professional activities. For more information: https://www.linkedin.com/in/nektarioskaranikas/ Learn more about your ad choices. Visit megaphone.fm/adchoices

As researchers look for ways to reduce the need for animals in their studies, new alternative methods (NAMs) are an intriguing route to capture crucial safety data and help advance drug discovery and development – specifically, virtual control groups (VCGs).   Join Steve Bulera, CVP and Chief Scientific Officer for Safety Assessment and Toxicology at Charles River, as he discusses how VCGs can be a viable alternative to research models, what it would take for the industry to widely accept NAMs, and how they can revolutionize research for the future.Show NotesVirtual Control Groups  Sounds of Science E73: Virtual Control Groups Modernizing Drug Development with Virtual Control Groups Virtual Control Groups: A Data-Driven Novel Method Revolutionizing the Future of Safety Studies Charles River Laboratories Announces Development of Nonclinical Virtual Control Groups with Sanofi to Reduce the Use of Animals 

The days may feel long, but the weeks quickly fly by, and this week is no exception. It's hard to believe we're already putting May in the rearview mirror. As usual, there were far too many updates to cover in a single episode; however, I'll be covering some of the ones I think are most notable. Thanks also to all of you who send feedback and topics for consideration. Keep them coming! With that, let's hit it. Reddit Chaos - I'm not a big fan of "told you so" moments, but there is a subtle satisfaction that comes when they arrive. When it comes to connecting Reddit to GenAI, it didn't take long for that moment to show up. As predicted, the lack of data cleaing practices and validation criteria went as expected and there has been a slew of crazy responses. Check them out if you want a good laugh (or cry). OpenAI Safety & New Model - GPT-What?! That's right, OpenAI has officially announced it has started training the successor of GPT-4. While we still don't have an official name, speculation on what we can expect to see is well on its way. Whatever is cooking, it must pack a punch since alongside that announcement came the announcement to formalize a new Safety Board. While it no doubt was influenced by the recent safety execs, it's a step in the right direction. Stanford Transparency Index - How much do we really know about how the AI sausage is made? According to a six month study by Standford, not a lot. Their Transparency Index highlights that while there has been improvements since Oct 2023, there is still a lot of room for improvement. Add to that, the "improvements" can be a bit misleading if you look beneath the surface. Google Safety Framework - Google has shared its safety framework, outlining the process they'll be following to assess when their models approach pre-defined risk thresholds, triggering mandatory mitigation planning. While it's good to have a well defined process, it's hard to know how effective it will be when it's not quite clear what exactly crosses the line. AI Kill Switch - When a global group of the largest, privately-held AI providers get together and universally agree on a "kill switch," you can't help but ask yourself "what kind of monster have we created?" Another step in the right direction that reveals a lot about where we are on the tech journey. And, I can't help but wonder what it really will take to "put down" one of these Leviathans. Show Notes: In this weekly update, Christopher spends dedicates a large portion of this update to AI safety and governance. Key topics include the missteps of AI's integration with Reddit, concerns sparked by the departure of OpenAI's safety executives, and Stanford's Model Transparency Index. The episode also explores Google's safety framework and global discussions on implementing an AI kill switch. Throughout, Christopher emphasizes the importance of transparency, external oversight, and personal responsibility in navigating the rapidly evolving AI landscape. 00:00 - Introduction 01:46 - The AI and Reddit Cautionary Tale 07:28 - Revisiting OpenAI's Executive Departures 09:45 - OpenAI's New Model and Safety Board 13:59 - Stanford's Foundation Model Transparency Index 24:17 - Google's Frontier Safety Framework 30:04 - Global AI Kill Switch Agreement 38:57 - Final Thoughts and Personal Reflections #ai #cybersecurity #techtrends #artificialintelligence #futureofwork

In this ToxChats© podcast, we spoke with Dr. René Meisner, Head of Safety Assessment at Denali Therapeutics, on using both transgenic and disease mouse models in a drug development program. Topics include considerations for program design, regulatory interactions, and the role of these mice moving forward. s for program design, regulatory interactions, and the role of these mice moving forward. 

John Lannon, Chief Executive of migrant support organisation Doras and Barry Ward, Fine Gael Senator

In this podcast, Dr. Tetyana Cheairs gives a detailed overview of the fertilized egg model and how it is currently being used in safety assessment studies. She then describes important ways in which toxicologists and drug development programs could benefit from utilizing the fertilized egg model. This podcast is incredibly informative and is tailored to be understood and enjoyed by a broad scientific audience. Dr. Cheairs is an Assistant Professor of Pathology, Microbiology, and Immunology at New York Medical College, where she leads an innovative research program focused on using nonanimal models to study the hazardous effects of chemicals. As a result of her active involvement in teaching activities, she was appointed as Assistant Dean for PhD Programs at the Graduate School of Biomedical Sciences in 2019.

Part of State Highway 2 between Wairoa and Napier has reopened on Tuesday morning, following a safety inspection A stretch of the road between Kotemaori and Pūtōrino was closed for most of Monday and overnight, following a slip on Sunday. Wairoa mayor Craig Little says the key access road is suffering continuous closures - isolating the town and putting unfair pressure on residents.  He is calling for longer-term solutions to increase resilience and prevent slipping. Waka Kotahi regional manager of maintenance and operations Mark Owen spoke to Corin Dann.

In the concluding episode of the 2023 series, Chris Miles, Commercial Director at the FPA is joined by the FPA's newly appointed Technical Director, George Edwardes; and Andy Miller, Loss Control Engineering Technical Manager at Allianz, to discuss a new fire safety assessment test for external cladding systems, RISC 501, which has been developed following an FPA research project into real world cladding fires and how they correspond with fire tests. Together they explore the issues with the current route to compliance from both a testing and insurance perspective, which led to the creation of RISC 501 due to be released by RISCAuthority (an annually funded research scheme administered by the FPA) in November 2023.

Patrick Youle, Director Safety Assurance (Technical), Axess Advisory, Sydney.Patrick started his career as an Avionics Systems Engineer in British Aerospace Defence Ltd, Later he worked as a Senior Engineer in Mott Macdonald, UK. In 2001 he worked as a Head of Rail Telecoms in Owen Willaims Railways. In 2006, he started as working as Project Safety Manager in Rio tinto and later worked in many organizations like Delta Rail, Anasaldo STS, MRX Technologies, Stanway Consulting Limited, PKY Associates, Ricardo Rail & Systra Scott Lister. In 201, Patrick started his company called Axess Advisory.Patrick is a chartered Engineer with 30 years' experience of Engineering Safety Management (ESM), Rail Telecommunications and Safety Assurance in the UK and Australia. Patrick has working knowledge of safety standards and guidelines including 'Yellow Book', iESM, European CSM, CENELEC EN 50126/8/9, 50159), international (IEC 61508 and ISO 31000), LUL and UK Network Rail standards. Equally familiar with Australian rail safety legislation and standards through roles in WA, NSW, Queensland and Victoria.Patrick is a Qualified rail telecoms engineer (member of the IRSE by examination). Patrick is familiar with the different technologies and applications (operational and non-operational) employed on the railways including lineside telephony, radio, telephone concentrators, exchanges, transmission (including SDH), TDM systems, SCADA data links, passenger information systems, public address systems, CCTV and station clocks. 

(0:50) - Exploring new methods for increasing safety and reliability of autonomous vehicles

High Reliability Organisations - held in high esteem in safety circles and now being actively investigated by businesses looking to improve their own safety performace, but what are they? In this the first of two special episodes of the conversation Nicola MacPhail talks to Associate Professors Drew Rae and Nektarios Karanikas about High Reliability Organisations and their charecteristics. Dr Drew Rae is an Associate Professor in the Safety Science Innovation Lab at Griffith University, where he teaches courses on research methods and safety engineering, and manages the lab's research program. Drew's own research uses a mix of ethnography, field experiments and theory-building to investigate organisational safety practices. He is particularly interested in understanding the myths, rituals and bad habits that surround the work of managers and safety practitioners, and how this work influences front-line operations. Drew co-hosts the Safety of Work podcast and is on the editorial board of the journal Safety Science.Nektarios Karanikas is Associate Professor in the Health, Safety and Environment discipline of the School of Public Health & Social Work at QUT. He studied MSc Human Factors and Safety Assessment in Aeronautics at Cranfield University (UK), and he was awarded his doctorate in Safety and Quality Management from Middlesex University (UK). Nektarios worked for over 19 years as an officer at the Hellenic Air Force where he served in various positions related to maintenance, safety and quality management, including accident investigations. Besides his academic qualifications, he holds professional credentials in occupational health & safety, human factors, project management and engineering, and has been a member of various national and international associations. Nektarios has published an edited book and several chapters, (co)authored various peer-reviewed journal and conference articles with a focus on safety/risk management, presented his work in over 80 events, and he actively volunteers in a wide range of scientific and professional activities. Thanks for listening. We have some great guests coming up in future pods so get ready to learn. Until next time, enjoy the rest of your week, and stay safe. https://plus.acast.com/s/health-and-safety-conversations. Hosted on Acast. See acast.com/privacy for more information.

In the latest sponsored DDW Sitting Down With podcast Professor Ruth Roberts, Co-Founder ApconiX and Claire Sadler, Project Toxicologist, discuss the benefits of carrying out a target safety assessment (TSA) during drug discovery and development whenever a biological target is going to be modulated. The speakers outline how TSAs can be used throughout the drug discovery and development pathway and offer examples of best practice and potential next steps. Listen now. 

Consumers today are making more meaningful purchasing choices when it comes to natural products and essential oils have attracted great interest in recent years. Even though essential oils are natural substances derived from plants, it doesn't mean they should automatically be considered safe for consumers. Join our industry experts, Héloïse Pikkety and  Amélie Cordonnier, as they discuss essential oil and how to assess its safety.Follow us on Twitter and LinkedIn

Sometimes, you might find yourself drowning in paperwork due to high numbers of accidents and insurance claims. And because of this, you might find yourself focused on just settling these instead of finding ways to improve safety and reduce the number of accidents and injuries. So, tune in to this episode where I talk about how I use Safety Assessment to drastically reduce the number of injuries. Show notes for this episode can be found at: https://thesafetygeek.com/91 Links Mentioned: Safety Management Academy - https://thesafetygeek.com/sma -------- Thank you for taking the time to listen to this episode. If you liked it, be sure to share it with your best safety friend. It's a goal of The Safety Geek to elevate the safety manager position and that is why I share tips and resources on how you can manage your safety program more effectively. Safety is safety, if you're a general industry nerd like me or if you work in construction, agriculture, environmental or other areas. The common factor is getting management support and employee participation. That's where I can help. To get started, take my FREE COURSE on how to manage your workplace safety program with ease where you will learn the basic steps from organizing all the moving parts of a safety program and building safety awareness. Join The Safety Geek Community and become part of The Squad where you get access to monthly safety webinars at https://community.thesafetygeek.com Check out Safety Management Academy! https://TheSafetyGeek.com/SMA Visit the website at https://TheSafetyGeek.com Subscribe to the YouTube Channel at https://www.youtube.com/c/safetygeek Sign Up for my safety newsletter where I share exclusive tips, content, forms, and templates at https://TheSafetyGeek.com/Newsletter Follow me @ Facebook: https://www.facebook.com/TheSafetyGeek LinkedIn: https://www.linkedin.com/in/brye-sargent/ Instagram: https://www.instagram.com/safety_brye/ Pinterest: https://www.pinterest.com/thesafetygeek/ Twitter: https://twitter.com/Safety_Brye

Dr Nektarios Karanikas talks about human factors, visions and goals, the power of language in the field of safety, and how organisations shift from the name, blame and shame culture. A truly amazing guest who I was honoured to have on the show. Nektarios Karanikas is Assoc. Prof in the Health, Safety and Environment discipline of the School of Public Health & Social Work at QUT. He studied MSc Human Factors and Safety Assessment in Aeronautics at Cranfield University (UK), and he was awarded his doctorate in Safety and Quality Management from Middlesex University (UK). Nektarios worked for over 19 years as an officer at the Hellenic Air Force where he served in various positions related to maintenance, safety and quality management, including accident investigations. Besides his academic qualifications, he holds professional credentials in occupational health & safety, human factors, project management and engineering, and has been a member of various national and international associations. Nektarios has published an edited book and several chapters, (co)authored various peer-reviewed journal and conference articles with a focus on safety/risk management, presented his work in over 80 events, and he actively volunteers in a wide range of scientific and professional activities.Links in the showSafety Insights Book: https://www.routledge.com/Safety-Insights-Success-and-Failure-Stories-of-Practitioners/Karanikas-Chatzimichailidou/p/book/9780367555931 Personal profilesQUT: https://www.qut.edu.au/about/our-people/academic-profiles/nektarios.karanikasLinkedIn: https://www.linkedin.com/in/nektarioskaranikas/ QUT OHS programmesOHS Graduate Diploma: https://www.qut.edu.au/courses/graduate-diploma-in-occupational-health-and-safetyHSE Master: https://www.qut.edu.au/courses/master-of-health-safety-and-environment Thanks for listening. We have some great guests coming up in future pods so get ready to learn. Until next time, enjoy the rest of your week, and stay safe. https://plus.acast.com/s/health-and-safety-conversations. Hosted on Acast. See acast.com/privacy for more information.

Join Chris, Rachel, and Brook for part 2 of our conversation with Greg and Brad from Arcadia Cognerati. If you are in need of school safety or crisis response resources, you can reach Dr. Team at schoolsafety@txasp.org Got a question or comment? reach us at podcast@txasp.org Intro/Outro Music by Shane Ivers - https://www.silvermansound.com

Mandated by regulatory bodies the world over, the thorough and precise evaluation of a new drug's cardiac effects is a critical element of new chemical entity development. Sponsors must submit all new chemical entities with systemic exposure to a dedicated thorough QT study (also referred to as TQT study) to understand the drug's impact on ECG parameters and determine whether the compound prolongs the corrected QT (or, QTc) interval. In Issue 9, we discuss global regulations, design, and timing of QT assessment, including a case study from a first-in-human clinical trial. Click here to download a readable, PDF version of Issue 9: https://www.altasciences.com/sites/default/files/2022-04/The-Altascientist_issue9_TQT_2022.pdf CHAPTERS: - 0:08 — Section 1: Introduction - 1:50 — Section 2: Global Regulations - 3:49 — Section 3: QT/QTc Study Design - 7:01 — Section 4: Timing of Assessment - 9:36 — Section 5: Case Study — First-in-Human Clinical Trial Involving QT Assessment - 12:09 — Section 6: Cardiac Assessment Specializations Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences' integrated, full-service solutions include preclinical safety testing, clinical pharmacology and proof of concept, bioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.

This episode we speak with Selina Cox and Kevin Whelan from the Department of Nutritional Sciences at King's College London about their paper in the June 2021 issue of Nutrition Reviews. Their paper is review on the role of food additive emulsifiers and critical assessment of the current estimations of exposure to emulsifiers. Join us for this conversation.

Paul Sidney, Senior Director, Compliance and Regulatory Affairs, and Julie Forget, Director, Safety Assessment, present a comparison of the U.S. FDA and Health Canada CTA submission process to support first-in-human phase I clinical trials. Learn more about: • How data from nonclinical studies in support of an IND submissions is submitted to foreign receiving authorities • The Clinical Trial Application review process (what to include and expected timelines) • The differences and similarities between the U.S. FDA and Health Canada

Check off location of observed hazards that may cause a fall under each category. Place the total number to the right of each category heading.

Vanilla ice cream in a cone with chocolate syrup and sprinkles. Sound amazing, right?Well think again! Our listeners Signe and Line have informed us that ice cream contains beaver butt, and we've put Mark on the case! The ice cream might also contain poison! A very real threat about a hundred years ago when the Poison Squad was founded to show the world that they were about to die from food.Check out our merchandise bit.ly/spækshopRate us on iTunes! bit.ly/spækitunesSend us water-hilarious science (it's an inside joke) or ask a question on facebook, twitter, or to spaekbraettet@gmail.comIt's our own music now, baby!References:G. A. Burdock (2007) Safety Assessment of Castoreum Extract as a Food IngredientSupport the show (https://spaekbraettet.10er.app/)

Dr. Nancy Chescheir, Editor-in-Chief, and Dr. John Fischer, Web Editor, review the articles that have been designated as Editors’ Picks for the April 2019 issue (Safety Assessment of a Large-Scale Improvement Collaborative to Reduce Nulliparous Cesarean Delivery Rates; Hypertensive Postpartum Admissions Among Women Without a History of Hypertension or Preeclampsia; Change in Second-Trimester Abortion After Implementation of a Restrictive State Law). This podcast features an interview with Dr. Elliott Main, corresponding author of the safety assessment article.

You can support our content by purchasing your CBD oil here: BlueBird Botanicals: cbdschool.com/bluebird-cbd - Discount code FIRSTTIME - 20% OFF! NuLeaf Naturals: cbdschool.com/nuleaf-cbd - Discount code CBDSCHOOL - 20% OFF! Visit CBD School to learn more about CBD: https://www.cbdschool.com/ Show Notes The latest and greatest from the CBD oil space for June 17, 2018. References (in order of appearance): Billy Caldwell: 'Let me treat epileptic son at home', says mum: https://www.bbc.com/news/uk-44510224 Sister-in-law of Home Office Minister who banned cannabis oil confesses: I have used it too, so make it legal: http://www.dailymail.co.uk/news/article-5852423/Sister-law-Home-Office-Minister-banned-cannabis-oil-reveals-uses-it.html State approves Pulaski hemp business: http://www.somerset-kentucky.com/news/state-approves-pulaski-hemp-business/article_a9dc1e04-71c4-11e8-9d27-5372d4451175.html CV Sciences, Inc. Announces Landmark Publication on the Toxicology and Safety Assessment of Base Material of its PlusCBD Oil™ Products: http://markets.businessinsider.com/news/stocks/cv-sciences-inc-announces-landmark-publication-on-the-toxicology-and-safety-assessment-of-base-material-of-its-pluscbd-oil-products-1027104828 Research undermines medical marijuana claims: https://newsok.com/article/5598310/research-undermines-medical-marijuana-claims The DEA has been seizing hemp shipped to this Wilmington CBD producer. Here’s why: https://portcitydaily.com/local-news/2018/06/12/the-dea-has-been-seizing-hemp-shipped-to-this-wilmington-cbd-producer-heres-why-2/ Will President Trump Really Support States' Rights On Marijuana?: https://www.entrepreneur.com/article/315014 Calgary eye surgeon cancels plans for medical cannabis clinic after Chinatown protest: http://www.cbc.ca/news/canada/calgary/chinatown-cannabis-clinic-protest-doctor-calgary-1.4709868 There’s a sea change coming for the $1 billion marijuana-based industry you’ve never heard of: http://www.businessinsider.com/marijuana-cbd-boom-cbd-2018-6 Texas Republican Party Endorses Marijuana Decriminalization: https://www.forbes.com/sites/tomangell/2018/06/17/texas-republican-party-endorses-marijuana-decriminalization/#568e9d925236 Inside the pioneering Cardiff laboratory exploring whether cannabis can be used to treat cancer: https://www.walesonline.co.uk/news/health/inside-pioneering-cardiff-laboratory-exploring-14486762 The house that's being built entirely out of hemp (but no, you can't smoke it): https://www.walesonline.co.uk/news/wales-news/house-thats-being-built-entirely-14790770 Tennessee's 1st Hemp Dispensary Opens In Murfreesboro: https://www.newschannel5.com/news/tennessees-1st-hemp-dispensary-opens-in-murfreesboro

Operators traveling to Europe need to be prepared for a Safety Assessment of Foreign Aircraft (SAFA) inspection. “It's geared toward foreign aircraft operators, so if you are based outside the European Union, and you're flying into the EU, that's their method for ensuring that you're safe while operating in their airspace,” said NBAA Operations Manager Brian Koester, adding that advanced preparation is key in making the process as smooth as possible. In this edition of NBAA Flight Plan, Koester shares three tips for getting ready for a SAFA inspection.

Operators traveling to Europe need to be prepared for a Safety Assessment of Foreign Aircraft (SAFA) inspection. “It’s geared toward foreign aircraft operators, so if you are based outside the European Union, and you’re flying into the EU, that’s their method for ensuring that you’re safe while operating in their airspace,” said NBAA Operations Manager Brian Koester, adding that advanced preparation is key in making the process as smooth as possible. In this edition of NBAA Flight Plan, Koester shares three tips for getting ready for a SAFA inspection.

RT Bullock, K Ventilator Safety Assessment Podcast 071015 by OPENPediatrics

RT Bullock, K Patient Safety Assessment Podcast 071015 by OPENPediatrics

Please share with your community: Share List A dear friend of mine, Dave, and I got together for a little while to have a Skype conversation on about some important work he performs in the pharmaceutical drug design industry. He answers questions with respect and really made me feel like a student by truly caring … Continue reading Podcast Episode 4: Interview with Dave, Pharmaceutical Safety Assessment → The post Podcast Episode 4: Interview with Dave, Pharmaceutical Safety Assessment appeared first on Welcome.

Gluten-free expert, author, coach and advocate Jules Shepard hosts a weekly show offering news, interviews with intriguing guests, gluten-free baking tips and otherwise lively conversation. This week Jules will be joined by Andrea Levario, the Executive Director of the American Celiac Disease Alliance (ACDA). Under Ms. Levario’s leadership, the ACDA has fought for many policy initiatives on behalf of those with celiac disease. Most recently, the independent organization 1in133.org selected the ACDA as its partner group to push for finalization of FDA gluten-free food labeling standards. Together, they have achieved this goal, with the FDA’s release Wednesday of its Safety Assessment, just 3 months after 1in133’s Gluten-Free Labeling Summit. Ms. Levario will be on with Jules to discuss what happens next with these proposed regulations and how the gluten-free community can best respond to the FDA’s proposed standard so we may all enjoy safer gluten-free labeling in the United States as soon as possible.