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The standard approach of “7 + 3” chemotherapy in acute myeloid leukemia (AML) treatment has been in place for 50 years. But that may soon change, says Maximilian Stahl, MD, a member of the Adult Leukemia Group at the Dana-Farber Cancer Institute in Boston and a member of the faculty at Harvard University. “My prediction is that in 10 years, you will not see much 7 + 3 anymore. Maybe not even 10 years, maybe five years,” he tells Robert A. Figlin, MD, the interim director and Steven Spielberg Family Chair in Hematology-Oncology at the Cedars-Sinai Cancer Center in Los Angeles. Dr. Stahl describes how targeted therapies such as menin inhibitor revumenib (Revuforj), which was recently approved by the U.S. Food and Drug Administration, are transforming AML care. Although currently indicated for relapsed/refractory disease, trials are exploring frontline use. “Pretty much, if you can think of any combination treatment in your head, that is already an ongoing clinical trial,” Dr. Stahl explains. He outlines how targeted therapies have already changed practice and looks to what advances are likely in the near future. Dr. Stahl reported a consulting or advisory role with the Boston Consulting Group, Clinical Care Options, Curis Oncology, GlaxoSmithKline, Haymarket, Kymera, Novartis, and Sierra Oncology. Dr. Figlin reported various financial relationships.
Moving is never easy. It can disrupt our routines, pull us away from friends, and fill us with uncertainty. Yet sometimes, we know deep down that we're being called to […] The post It's Time To Move appeared first on Broken Door Ministries.
[00:00:00] Sandra Smith [00:18:26] Rep. Steve Scalise [00:36:50] Rich Lowry [00:55:13] Elisabeth Hasselbeck [01:13:37] Tom Homan [01:32:00] Jacqui Heinrich Learn more about your ad choices. Visit podcastchoices.com/adchoices
Sometimes you just have to MOVE on.....when it's best for you.
Hour 3 of the Killer B's with Joel Blank, and Jeremy Branham included... Should we just be focusing on the development on Cam Smith above everything else The guys chat with Reid Gettys on Houston Cougars and the NCAA Tournament Who's going to lead the Astros in home runs this season? Car Wreck of the Day
In this week's rendition we are joined again by Jasey Cones and discuss; hidden gems, parents on the eddies, when it is time to joke about tragedies, we book a World of T-Shirts tour and much more. Sit back, crack a couple cold ones and join this week's Cooped-Up Conversation!
3rd hour of the G-Bag Nation: Sounds of the sports day; Woolly Bully's Top 10; Around the Mavs: What do you think about the people telling us it's time to move on? full 2384 Wed, 12 Mar 2025 22:25:21 +0000 xk9ftfPHDOD06OfZ09kZdd24Z9P4R6WV sports GBag Nation sports 3rd hour of the G-Bag Nation: Sounds of the sports day; Woolly Bully's Top 10; Around the Mavs: What do you think about the people telling us it's time to move on? The G-Bag Nation - Weekdays 10am-3pm 2024 © 2021 Audacy, Inc. Sports
The Official Corporate Podcast of Antioch, The Apostolic Church
Former Cowboys head coach Dave Campo and Joe C from XL Primetime dive into the details on 'Campo and Joe.
“Our military neutrality effectively ended last week. It happened in the course of an hour, when Volodymyr Zelenskyy was forced to stand up for himself and his country against two schoolyard bullies and was then thrown out of the White House.” So wrote Fergus Finlay, Columnist with The Irish Examiner who joined us on Newstalk Breakfast this morning.
Today, McKay talks all about action on the podcast, starting off the episode by recounting Ernest Shackleton's 1914 expedition to Antarctica. After two years of combatting ice, cold temperatures, and the ocean, Shackleton finally managed to save his team and bring them home. McKay attributes his unlikely success to his willingness to move and set his plans into action, and points out that many of us overthink far too much and are paralyzed by our thoughts. To overcome our overthinking, action is the best remedy - making moves, changing our thought processes, and cultivating what McKay calls our emotional homes are key to success.During the latter half of this episode, McKay introduces Larry Lemieux, an Olympic sailor who made the heroic decision to forfeit his pursuit of the gold medal to save his competitors drowning in the water. It was his quick action skills that made this move possible - he didn't overthink. Likewise, McKay draws this episode to conclusion by detailing Sarah Lift's decision to leave her abusive household at the age of 15. He says that her fast acting, like that of Lemieux, changed her life and led her down a path to emotional freedom and financial success. Listen in today as McKay demonstrates that, truly, “there is power in moving and keeping your focus on the next necessary part of your life's journey.”The Finer Details of This Episode:Ernest Shackleton's 1914 mission to Antarctica Why overthinking is a bad habit Why action assuages overthinkingThe importance of a healthy emotional homeLarry Lemieux's heroic move at the OlympicsSara Lift's decision to leave her abusive householdQuotes:“We let habitual thinking freeze us from time to time, and the way out of our situation, or to safety or success, just might be to move. Action is a powerful force, not only in our life, but in our minds.”“The problem with overthinking is it can become a habit, and soon we get hung up on relatively simple decisions. We worry excessively, our mind tends to go into overdrive, and we even begin to think about our thinking.”“Overthinking can prevent us from taking action by keeping us trapped in circular thoughts. When we overthink, we may be unable to separate facts and what we know for sure from the worries we keep telling ourselves.”“You can't start the next chapter of your life if you keep rereading your last one.”“Overthinking plagues many of us, and we can change the rumination going on in our life and our thinking by focusing on what's next.”“Stand guard at the door of your mind. Only build rooms for the people and technology that helps you direct your thinking.”Links:Open Your Eyes with McKay Christensen
The markets are counting down to the tariff implementation tomorrow and a potential government shutdown next week. Can investors handle the political uncertainty? Plus, the President announces he will back a bitcoin strategic reserve. We speak with Microstrategy's (Strategy) CEO on why the U.S. needs one to stay ahead of the world. And, as the tech trade continues to underperform is it time to pivot to healthcare?
In this episode of Go Gaddis Real Estate Radio, Cleve Gaddis covers:
The guys debate if it's time for the Falcons to look for a new home for the vet DT
Big O says it's time to move on from Terron Armstead
We never like to call for anyoneʻs job, but, the menʻs basketball team at UH is a mess and getting worse. Players seem to be quitting after constant lineup changes and attendance seems to be at an all time low for the Stan. We discuss, plus, lots of NBA Lakers talk, Wemby and March Madness is right around the corner!
It's Time To Move And No Fly Zone | Jentzen Franklin | City Light Vegas by Jabin Chavez
Your Daily Prayer
Pr. Chris Rosebrough of Fighting for the Faith Fighting for the Faith The post This Week in Pop-Christianity: Jentezen Franklin's Sermon “It's Time to Move” – Pr. Chris Rosebrough, 2/21/25 (0522) first appeared on Issues, Etc..
The Pittsburgh Steelers are preparing for the new league year, and looking at positional needs heading into March. On this episode of "Let's Ride", host Jeff Hartman talks all about the Steelers options at running back, both in-house and outside free agents. Also on this episode is the All Betz Are Off segment with Jeremy Betz and the Hart to Heart segment. This podcast is a part of the Steel Curtain Network, a proud member of the Fans First Sports Network. Learn more about your ad choices. Visit megaphone.fm/adchoices
Chad opens the show with Minneapolis Mayor Jacob Frey on several topics including trying to move forward with a plan for George Floyd Square, the MPD consent decree, concerns from citizens about deportation and more.
The Pittsburgh Steelers fan base is still fuming over the way the 2024 season finished, but it is time to move onto the 2025 league year about to begin in March. In the start of a new feature on the "Let's Ride" host Jeff Hartman is going to dive into free agent options for the Steelers. This first installment of "time to move on" talks about the wide receiver position. Also on this episode is the ever-popular Mailbag Segment, all on the Wednesday podcast. This podcast is a part of the Steel Curtain Network, a proud member of the Fans First Sports Network. Learn more about your ad choices. Visit megaphone.fm/adchoices
Word on the streets is that moving homes is ranked as being one of the most stressful events in a person's life, so naturally, we're comin in hotttt this week with some solid perspective shifts that have helped us keep our heads on straight as we move into our new spots. And of course, we had to dive into how epic it's been living with each other for the past few years. We're forever grateful for this space and we thank you for growing alongside us, Cowboys. Talk soon! xoxoLet's Connect Follow us on Instagram: @theconsciouscowboys Learn more at theconsciouscowboys.com Watch our full episodes and more on Youtube: The Conscious Cowboys _____We're two best friends who are building a brand with the mission of amplifying what it means to be well. We strive to be as authentic as possible so that our conversations facilitate true connection while building upon a community that values a more conscious way of life. We're known as “The Cowboys” by those we love, so it's only fitting that our brand reflects exactly who we are. We release an episode every Wednesday, so tune in, and enjoy this wild ride.
Is It Time To Move On From Moser? All Star Weekend Reviews! USA Beats Canada in Hockey! Aberg Wins at Torrey! MUCH MORE!!!See omnystudio.com/listener for privacy information.
The episode kicks off with an intro to Pull Hook Golf, followed by a recap of recent tournaments and LIV Golf updates. Buttsy shares his experiences at influencer events and the Waste Management Phoenix Open. The discussion includes Thomas Detry's performance and Brent Grant's reflections on his Korn Ferry Tour and Bogotá experiences. The episode also covers Torrey Pines betting odds, weather impacts, and insights into golf courses, betting, and caddy stories. LIV Golf's viewership, criticism, and future are explored, along with speculation on a potential merger with the PGA Tour. It wraps up with the Pull Hook Golf team's humorous social media takes and a sign-off.
The anniversary of the National Apology to the Stolen Generations has been commemorated in Federal Parliament. It has been 17 years since Prime Minister Kevin Rudd delivered a historic apology for racial discrimination against First Nations people. It is estimated that between one in three, and one in 10, Indigenous children were forcibly removed from their parents in the period between 1910 and 1970.
LISTEN TO THIS EPISODE IF YOU'RE WONDERING WHETHER IT'S TIME TO LEAVE A SITUATION THAT NO LONGER SERVES YOU In this episode, I'm sharing how to recognize when it's time to make a shift in your life. Whether it's a job, a relationship, or a routine, knowing when to let go can feel overwhelming, but it's essential for growth. I'll take you through the signs that it's time to move on, including when things stop flowing, when you feel stagnant, and when you've lost your spark for life. I'll also share my personal experiences of ignoring the signs and the wake-up calls that finally pushed me to make a change. We'll talk about why it's okay to question your life during this time of awakening, how to recognize alignment, and the small shifts you can make to start moving forward. If you've been feeling stuck or unsure, this conversation will inspire you to take that first step. Topics We Discuss: Personal Growth, Life Transitions, Intuition, Overcoming Stagnancy, Recognizing Alignment #LifeTransitions #PersonalGrowth #FollowYourIntuition
If the tumbling leaves of fall indicate anything let it be this: It's time to move! It's time to start thinking about what you want in the new year and preparing to achieve those goals. Today's guest is Majd, an employee who has built a longstanding relationship with Financial Finesse having spoken with 17 coaches since her first call. After explaining why now is the perfect time to start planning for 2025, Majd details her experience of calling Financial Finesse for the very first time, what she thinks of our coaches and the services she receives from us, how working with Financial Finesse broadened her understanding and relationship with money, and her advice for first-timers who are finally ready to call a financial coach. We also unpack the plethora of considerations when moving across state lines, the mistakes many make when changing jobs mid-year, common misconceptions about multi-state tax returns, and the importance of always having a healthy stash tucked away for rainy days. Key points from this episode:Why it's never too early to plan for your future. What prompted today's guest, Majd, to call Financial Finesse for the first time. Examining her living circumstances when she made the work move to Atlanta from L.A. and how to approach a big move.Common mistakes that people make when changing jobs mid-year. Everyday misconceptions about multi-state tax returns. How working with Financial Finesse has improved Majd's relationship with money.Her thoughts about financial coaching before and after receiving our services. What to consider when deciding between buying and renting when moving to a new city.The importance of establishing a healthy emergency fund before a big move. Majd's advice for making that first call to a financial coach. Quotes:“California does not offer a state tax deduction for contributing to the 529 plan, but Georgia does. So, if you're going to try to do something and make a contribution, why not have it optimized — from a tax perspective — by taking advantage of the state that does offer good deductions?” — Alesha Isaacs [12:48]“[Working with Financial Finesse has] changed things in the fact that I know that I have someone that I can trust.” — Majd [14:03]“[With Financial Finesse] I just feel empowered in the sense that if I need help with something, I know that there's someone to turn to, and I know there's someone that's going to take the time to explain things in a simple way.” — Majd [14:33]“I don't want to be driving to places that I think are basic necessities; I want to be able to walk. That's how I pretty much chose the area [where I live].” — Majd [19:26] Links mentioned in today's episode:Alesha Isaacs on LinkedInJulie Everett on LinkedIn Submit Your Questions via EmailFinancial Finesse
Jeff interviews Angela Lamb, where they discuss a prophetic word for 2025 and beyond regarding movement and acceleration, building, innovation and more! FOLLOW US: https://linktr.ee/elijahfireshow /// ElijahFire and ElijahStreams are part of Elijah List Ministries. Thank you for making the always-free Elijah List Ministries possible! Click here to learn how to partner with us: https://secure.qgiv.com/for/elijahfirepodcast
After a very emotional defeat for Kentucky & BBN, it's time for Kentucky to let go of the drama with coach Cal and move forward. #kentuckybasketball #basketball #nba #kentuckyhoops #kentuckywildcats #collegebasketball #bigblue #bbn
How are all my fellow Social Media Managers and Business Owners? What a crazy start to the year this has been. I mean, I don't usually rush to post an update when TikTok gets banned in the US, or there's ANOTHER algorithm change on instagram, or when TikTok gets reinstated, but it's hard to ignore what's been happening over the month of January in our industry alone! Usually I can just roll with the punches and take them in my stride, but this was even a lot for me guys. Listen as I briefly un pack Social Media, but also do my best to convince you that YouTube is where you need to be. If you haven't already, also check out my YouTube video from last year on 2025 Social Media Trends & Predictions: what you need to know. Some takeaways from this episode: The rise of YouTube and longform content YouTube's creator support and monetisation (something we actually get in NZ!) The future of content creation If any of my listeners found me via YouTube, I would love to know! Do you think I should make follow up episodes this year on YouTube? If you have the time, please could you rate and review this podcast or subscribe to it. It really helps us to continue making this free content for you and we just generally appreciate that you would do this for us! Have a great week guys!Ellen xx ~~~ Want to get more Ellen or Work with her and her team? Check out the Dishing Up Digital Agency website for more information and to contact us: https://www.dishingupdigital.com/ Join the Dishing up Digital School: https://www.dishingupdigital.com/courses Ellen's Instagram Page: https://www.instagram.com/ellenmackenziee/ Ellen on TikTok: https://www.tiktok.com/@ellenmackenzieee?lang=en Buy Ellen's Book: https://www.ellenmackenzie.com/book
We hope you enjoy today's Scripture reading and devotional aimed at motivating you to apply God's word while strengthening your heart and nurturing your soul. Today's Bible reading is Numbers 9:15–23. To read along with the podcast, grab a print copy of the devotional at https://www.crossway.org/books/daily-joy-hcj/. Browse other resources from Mary A. Kassian. Follow us on social media to stay up to date: Instagram Facebook Twitter
Clint Stoerner and Ron "The Show" Hughley discuss why it's time to move on from Chip Kelly dream...
Greg has been with his wife for 10 years and there is something about her physically that he would like her to change, and she is very against it! Learn more about your ad choices. Visit podcastchoices.com/adchoices
Gaming Time x Oceanhorn 2: Knights of the Lost Realm x Ecclesiastes 3:1-11Your daily crossover of faith and fandom! Experience daily Biblical encouragement from nerdy Christian podcasters, bloggers and content creators. Join the Nerd of Godcast community at www.NOGSquad.com
Welcome to Church!
This episode invites educators to prioritize their physical wellness by scheduling movement into their calendars, embracing the "all or something" mindset, and celebrating even small steps toward consistency. For episode resources, see SelfCareForEducators.com. Music: Happy Clappy Ukulele by Shane Ivers - https://www.silvermansound.com
Ryan and Trevor discuss the weekend of football. Is now the time for Coach McCaffery to leave the Hawks?
01/19/25 Fr Daniel Shaba - 2nd Sunday of Epiphany (English) by St. Peter's Chaldean Catholic Diocese
Hour 1 with Bob Pompeani and Joe Starkey: The Steelers season is over. The Steelers ended the year with a five-game losing streak and have now lost six playoff games in a row. Joe Starkey believes it's time for a divorce between the Steelers and Mike Tomlin. Kirk Herbstreit called out the Steelers on Amazon Prime for their lack of effort, saying "This is the Pittsburgh Steelers! Where is the fight!"
Packernet After Dark: It's Time to Move on
Packernet After Dark: It's Time to Move on
How do we know when it's time to move on from that relationship, friendship, or situationship? How do we know if we've been living in a pattern of bitterness? How can we walk in forgiveness? Lauren Vanderlinden is a sweet online friend, and someone whose path I have miraculously connected with (you'll hear our small-world meeting story). She's the author of a book all about moving on, healing, leaning on God's justice instead of revenge, and so much more. If you're hurting, or have been hurt before, and need a practically biblical conversation on how to move on, forgive, and live lighter, you're in the right place. Grab a copy of I Want To Move On today. -- OUR SPONSOR: Go to https://www.thrivemarket.com/truthtalks for 30% off your first order, plus a FREE $60 gift! -- Connect with Tara: Instagram / Her book / Her website / Her discount code page / YouTube / The free, email family / Sponsor a child through Compassion Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of 32 Thoughts, Kyle Bukauskas and Elliotte Friedman unpack the Elias Pettersson-J.T. Miller drama in Vancouver and prescribe a solution moving forward. They delve into Ottawa's impressive win over the Canucks and talk about their assentation into playoff contention (15:01). The Winnipeg Jets also get attention as they drubbed Minnesota 5-0 (20:00). Afterwards, they talk about Matt Rempe's 8-game suspension (25:08) before discussing Auston Matthews aggravating an injury (30:51). Kyle and Elliotte give Yaroslav Askarov his flowers after a 41-save effort Saturday (40:50) before discussing John Klingberg's attempt at a NHL comeback (42:27). The Final Thought focuses on the legal strife between the OHL and the USHL as a pair of American teams attempt to make the switch (45:00). Kyle and Elliotte answer your questions and respond to your voicemails in the Thought Line (52:48).In the final segment, Kyle and Elliotte pay tribute to the late Ricky Henderson before announcing and hearing from the winners of our live show ticket contest (1:12:27). Email the podcast at 32thoughts@sportsnet.ca or call the Thought Line at 1-833-311-3232 and leave us a voicemailThis podcast was produced and mixed by Dominic Sramaty and hosted by Elliotte Friedman & Kyle Bukauskas.The views and opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the position of Rogers Sports & Media or any affiliates