Podcasts about Dexmedetomidine

Dexmedetomidine — or “Dex” — has become one of the most intriguing and versatile drugs in the anesthesia world. In this episode of Anesthesia Alchemy with hosts Lynn Macksey, MSN, CRNA and Garry Brydges, PhD, DNP, MBA, CRNA, ACNP-BC, FAAN dive deep into the pharmacology, clinical application, and emerging research surrounding this alpha-2 agonist. Here's some of what we discuss in this episode:

Show notes at pharmacyjoe.com/episode1030. In this episode, I’ll discuss adding dexmedetomidine to lidocaine for topical application to prevent cough during extubation of thyroidectomy patients. The post 1030: Adding dexmedetomidine to lidocaine for topical application to prevent cough during extubation appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode1010. In this episode, I’ll discuss the use of dexmedetomidine to reduce vasopressor resistance in refractory septic shock. The post 1010: Does Dexmedetomidine Improve Vasopressor Sensitivity in Refractory Septic Shock? appeared first on Pharmacy Joe.

In this episode, we explore the pharmacological management of agitation in emergency settings, focusing on benzodiazepines and the novel medication dexmedetomidine. Did you know there's now a sublingual option that works through an entirely different mechanism than traditional anti-agitation medications? Faculty: Scott Zeller, M.D. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: The Psychopharmacology of Agitation: Managing Behavioral Emergencies The Role of Benzodiazepines and Dexmedetomidine in Managing Agitation

Get ahead with VETAHEAD and join Dr. Laila Proença™ on 15 minutes of ZooMed (exotic animal medicine) content. Today, let's unravel the latest advancements in avian sedation protocols! Join Dr. Laila Proença™ as she delves into groundbreaking research comparing the effectiveness of dexmedetomidine paired with either nalbuphine hydrochloride or butorphanol tartrate in chickens. Discover how these combinations can revolutionize handling and treatment for avian patients while minimizing stress—for the birds and you! Perfect for avian vets, technicians, and anyone navigating the world of pet or zoo-med chickens. Tune in for practical tips, clinical pearls, and a dose of feathered fun! Click here to get your VETAHEAD E-Magazine!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here to receive a VETAHEAD Gift!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Do you want to access more ZooMed (exotics) knowledge directly from specialists? Come with us and #jointhemovement #nospeciesleftbehind ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Head to VETAHEAD Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Join our VETAHEAD Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow @vetahead.vet on Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to @vetahead channel on YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow @vetahead on Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow @vetahead on TikTok

In this episode, host Alyssa Watson, DVM, welcomes Carrie Schroeder, DVM, DACVAA, to discuss her recent Clinician's Brief article, “Dexmedetomidine-Induced Bradycardia in a Great Dane.” The conversation centers around the physiological mechanisms underlying bradycardia and dexmedetomidine's biphasic blood pressure effects. Key aspects of the discussion include patient selection, drug combinations, monitoring protocols, and strategies for managing these cases, offering practical guidance on balancing dexmedetomidine's benefits with its potential risks.Resource:https://www.cliniciansbrief.com/article/heart-rate-veterinary-dexmedetomidineContact:podcast@instinct.vetWhere To Find Us:Website: CliniciansBrief.com/PodcastsYouTube: Youtube.com/@clinicians_briefFacebook: Facebook.com/CliniciansBriefLinkedIn: LinkedIn.com/showcase/CliniciansBrief/Instagram: @Clinicians.BriefX: @CliniciansBriefThe Team:Alyssa Watson, DVM - HostAlexis Ussery - Producer & Multimedia Specialist

In this episode of the Saving Lives Podcast, we dive into the DecatSepsis trial, exploring the role of dexmedetomidine in reducing mortality and managing septic shock. Discover how this sedative could help mitigate the harmful effects of the hyperadrenergic state in septic patients. The Vasopressor & Inotrope Handbook I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. If you're in the US, you can order ⁠⁠A SIGNED & PERSONALIZED COPY for $29.99⁠⁠ or via ⁠⁠AMAZON for $32.99⁠⁠ (for orders in or outside the US). Ebook versions are available via ⁠⁠AMAZON KINDLE for $9.99⁠⁠, ⁠⁠APPLE BOOKS⁠⁠, and ⁠⁠GOOGLE PLAY⁠⁠. ¡Excelentes noticias! Mi libro ha sido traducido al español y está disponible a traves de ⁠⁠AMAZON⁠⁠. Las versiones electrónicas están disponibles para su compra for solo $9.99 en ⁠⁠AMAZON KINDLE⁠⁠, ⁠⁠APPLE BOOKS⁠⁠ y ⁠⁠GOOGLE PLAY⁠⁠. Citation Ezz Al-Regal AR, Ramzy EA, Allah Atia AA, Emara MM. Dexmedetomidine for Reducing Mortality in Patients With Septic Shock A Randomized Controlled Trial (DecatSepsis). Chest. 2024 Jul 14:S0012-3692(24)04601-4. doi: 10.1016/j.chest.2024.06.3794. Epub ahead of print. PMID: 39004217. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show notes at pharmacyjoe.com/episode959. In this episode, I'll discuss whether there is a benefit from switching to dexmedetomidine when sedation is started with midazolam. The post 959: Is there a benefit from switching to dexmedetomidine when sedation is started with midazolam? appeared first on Pharmacy Joe.

Send us a Text Message.In dieser Folge besprechen wir die Arbeit von Yang et al. zum Einsatz von Dexmedetomidin plus Esketamin zur Schmerzreduktion während der Sectio Caesarea:Yang JR, Li YY, Ran TJ, et al. Esketamine Combined with Dexmedetomidine to reduce Visceral Pain During elective Cesarean Section Under Combined Spinal-Epidural Anesthesia: A double-Blind Randomized Controlled Study. Drug Des Devel Ther. 2024;18:2381-2392. Published 2024 Jun 18. doi:10.2147/DDDT.S460924Mit im Studio dabei: Dr. Eike Pfefferkorn, wissenschaftlicher Mitarbeiter der Klinik für Anästhesiologie

Episode 40– Noise Fear and Phobias – What you need to know!   Did you know that up to 50% of our pet dogs suffer from noise sensitivity, fear of noises or even noise phobias? That is a HUGE amount and most of them go undiagnosed and untreated. And that means that many of our pets suffer, either on a daily basis or during specific noise events such as fireworks and thunderstorms. Cats are likely also affected by noises, but because they tend to hide in these circumstances, pet caregivers might not notice this, and they are even less likely to get the help they might need.   In this episode, Dr Katrin chats about: ·         The different diagnoses when it comes to noises - is it a phobia, fear or sensitivity? ·         The signs your dog might show if they are fearful of noises ·         Why household electrical appliances are important ·         How dogs hear differently from humans and what that means for them ·         How we can manage the environment to help ·         Counter-conditioning to noises ·         Supplements, pheromones and medications   Here are some of the papers Dr Katrin mentioned in this episode: 1.      An open-label prospective study of the use of l-theanine (Anxitane) in storm-sensitive client-owned dogs, Amy L. Pike, Debra F. Horwitz, Heidi Lobprise, JVB, 2015, Vol 10:4, pp324-331, https://doi.org/10.1016/j.jveb.2015.04.001 2.      Dexmedetomidine oromucosal gel for noise associated acute anxiety and fear in dogs—a randomised, double-blind, placebo-controlled clinical study, Vet Record, 2017, M. Korpivaara, K. Laapas, M. Huhtinen, B. Schöning, K. Overall   We really hope you enjoy this episode; it is packed with so much information!   If you liked this episode of the show, The Pet Behaviour Chat, please LEAVE A 5-STAR REVIEW, like, share, and subscribe!   Facebook Group: Join The Pet Behaviour Community on Facebook   You can CONNECT with me: Website: Visit my website Trinity Veterinary Behaviour Instagram: Follow Trinity Veterinary Behaviour on Instagram Trinity Veterinary Behaviour Facebook: Join us on Trinity Veterinary Behaviour's Facebook page Trinity Veterinary Behaviour YouTube: Subscribe to Trinity Veterinary Behaviour on YouTube LinkedIn Profile: Connect with me on LinkedIn   Thank you for tuning in!

Management approach for electrical storm!For a deep dive into EKGs in wide complex tachycardias, take a look at this awesome lecture by Amal Mattu.References to articles mentioned in the podcast:Cheskes et al. Defibrillation Strategies for Refractory Ventricular Fibrillation. N Engl J Med. 2022 Nov 24;387(21):1947-1956Ortiz et al. Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study. Eur Heart J 2017;38(17):1329-1335Song et al. Association of Dexmedetomidine With New-Onset Atrial Fibrillation in Patients With Critical Illness. JAMA Netw Open 2023;6(4):e239955Wang etc. Effect of Dexmedetomidine on Tachyarrhythmias After Cardiac Surgery: A Systematic Review and Meta-Analysis. J Cardiovasc Pharmacol 2022;79(3):315-324Zhong et al. Dexmedetomidine Reduces Incidences of Ventricular Arrhythmias in Adult Patients: A Meta-Analysis. Cardiol Res Pract 2022;5158362Do et al. Thoracic Epidural Anesthesia Can Be Effective for the Short-Term Management of Ventricular Tachycardia Storm. J Am Heart Assoc. 2017 Oct 27;6(11):e007080Tian et al. Effective Use of Percutaneous Stellate Ganglion Blockade in Patients With Electrical Storm. Circ Arrhythm Electrophysiol. 2019;12(9):e007118Batnyam et al. Safety and Efficacy of Ultrasound-Guided Sympathetic Blockade by Proximal Intercostal Block in Electrical Storm Patients. JACC Clin Electrophysiol 2024;10(4):734-746

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What's up folks! This is Jon Lowrance with Anesthesia Guidebook and this is episode 103… a deep dive on dexmedetomidine with Eliana Zimmerman. This episode is coming out on January 21, 2024. Before we get to the show I want to remind folks that I'll be speaking in person at the Encore Symposiums' Autumn in […]

Ano Novo, artigos novos,  podcast novo.  A partir de agora, nossos ouvintes têm a opção de escolher direto o artigo que querem escutar, na ordem que preferirem. 90 versus 60 min of early skin-to-skin contact on exclusive breastfeeding rate in healthy infants' ≥35 weeks: A randomised controlled trialNosso primeiro artigo mostra como 30 minutos a mais podem influenciar positivamente a saúde dos recém-nascidos por até 14 semanas. Quer saber mais? Acesse o artigo em https://doi.org/10.1111/ apa.17021Trends in infant mortality due to haemolytic disease and other perinatal jaundice in the USA, 1999–2020Traz uma carta de um dos maiores estudiosos em icterícia na atualidade: Vinod K Bhutani. Um levantamento que nos faz pensar que apesar de toda a evolução da Neonatologia, ainda perdemos bebês para causas evitáveis. https://fn.bmj.com/content/early/2023/09/21/archdischild-2023-326006The Irritable Infant in the Neonatal Intensive Care Unit: Risk Factors and Biomarkers of Gastroesophageal Reflux DiseaseSempre que o nosso paciente apresentar sintomas de irritabilidade e de arqueamento das costas a gente precisa iniciar tratamento para DRGE? Descubra aqui: https://pubmed.ncbi.nlm.nih.gov/37777170/Use of Dexmedetomidine and Opioids in Hospitalized Preterm InfantsQual o crescimento do uso de Precedex nos últimos anos para sedação em neonatologia? Qual o impacto desse medicamento no uso de opioides?https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2811321?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamanetworkopen.2023.41033 Não esqueça: você pode ter acesso aos artigos do nosso Journal Club no nosso site: https://www.the-incubator.org/podcast-1 Se estiver gostando do nosso Podcast, por favor deixe sua avaliação no seu aplicativo favorito e compartilhe com seus colegas. O nosso objetivo é democratizar a informação. Se quiser entrar em contato, nos mandar sugestões, comentários, críticas e elogios, manda um e-mail pra gente: incubadora@the-incubator.org

In this 270th episode I welcome Drs. Michael Douglas and Leonard Soloniuk to the show to discuss the use of dexmedetomidine in spinals, epidurals and nerve blocks. Our Sponsors:* Check out Magic Mind and use my code ACC20 for a great deal: https://www.magicmind.com/Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Dr. Mark Oldham, Associate Professor of Psychiatry at University of Rochester Medical Center, President-Elect of the American Delirium Society, and Deputy Editor of the Journal of the Academy of Consultation-Liaison Psychiatry, takes us through a deep dive on delirium. This episode covers an enormous amount of material. Contrast  encephalopathy and delirium before diving into the dangerousness of delirium and prevention strategies. Explore the neurobiology of delirium and tie it to validated assessment tools and treatment approaches. We also discuss areas for future research, and learn to appreciate the evolutionary function that delirium serves.This episode also deserves some references! (3:38) Lipowski ZJ. Delirium: Acute Brain Failure in Man. Springfield, IL: Charles C Thomas, 1980.  (7:55) Slooter AJC, Otte WM, Devlin JW, et al. Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies. Intensive Care Med. 2020;46(5):1020-1022.  (21:46)  Marcantonio ER, Ngo LH, O'Connor M, et al. 3D-CAM: derivation and validation of a 3-minute diagnostic interview for CAM-defined delirium: a cross-sectional diagnostic test study [published correction appears in Ann Intern Med. 2014 Nov 18;161(10):764]. Ann Intern Med. 2014;161(8):554-561.   (29:50) Kunicki ZJ, Ngo LH, Marcantonio ER, et al. Six-Year Cognitive Trajectory in Older Adults Following Major Surgery and Delirium. JAMA Intern Med. 2023;183(5):442-450.   (41:40) Mews MR, Tauch D, Erdur H, Quante A. Comparing consultation-liaison psychiatrist's and neurologist's approaches to delirium - A retrospective analysis. Int J Psychiatry Med. 2016;51(3):284-301. = (1:08:08) Girard TD, Exline MC, Carson SS, et al. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med. 2018;379(26):2506-2516.   (1:09:33) Hui D, Frisbee-Hume S, Wilson A, et al. Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial. JAMA. 2017;318(11):1047-1056.   (1:31:36) By the 2023 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2023;71(7):2052-2081.  (1:33:54) Burton JK, Craig LE, Yong SQ, et al. Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2021;7(7):CD013307. Published 2021 Jul 19.   (1:35:41) Skrobik Y, Duprey MS, Hill NS, Devlin JW. Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial. Am J Respir Crit Care Med. 2018;197(9):1147-1156.   (1:36:00) Subramaniam B, Shankar P, Shaefi S, et al. Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial [published correction appears in JAMA. 2019 Jul 16;322(3):276]. JAMA. 2019;321(7):686-696. 

Contributor: Travis Barlock MD Educational Pearls: Common sedatives used in the Emergency Department and a few pearls for each. Propofol Type: Non-barbiturate sedative hypnotic agonizing GABA receptors. Benefit: Quick on and quick off (duration of action is approximately 2-7 minutes), helpful for suspected neurologic injury so the patient can wake up and be re-evaluated. Also has the benefit of reducing intracranial pressure (ICP). Downsides: Hypotension, bradycardia, respiratory depression. What should you do if a patient is getting hypotensive on propofol? Do not stop the propofol. Start pressors. May have to reduce the propofol dose if delay in pressors. Dexmedetomidine (Precedex) Type: Alpha 2 agonist - causes central sedation Uses: Patients are more alert and responsive and therefore can be on BiPAP instead of being intubated. Does not cause respiratory depression. Downsides: Hypotension and Bradycardia. Caution in using this for head injuries, its side effects can mask the Cushing reflex and make it more difficult to spot acute elevations in ICP and uncal herniation. Ketamine Type: NMDA antagonist and dissociative anesthetic, among other mechanisms. Benefits: Quick Onset (but slower than propofol). Does not cause hypotension, but can even increase HR and BP (Thought to potentially cause hypotension if patient is catecholamine-depleted (ie. sepsis, delayed trauma)). Dosing ketamine can be challenging. Typically low doses (0.1-0.3mg/kg (max ~30mg)) can give good pain relief. Higher doses (for intubation/procedural sedation) are generally thought to have a higher risk of dissociation. Downsides: Emergence reactions which include hallucinations, vivid dreams, and agitation. Increased secretions. Benzos Type: GABA agonists. Benefits: Seizure, alcohol withdrawal, agitation due to toxic overdoses.  Push doses are useful because doses can stack. Longer half-life than propofol.   Downsides: Respiratory depression. Longer half-life can make neuro assessments difficult to complete. Etomidate MOA: Displaces endogenous GABA inhibitors. Useful as a one-time dose for quick procedures (cardioversion, intubation). Often drug of choice for intubation since it is thought to have no hemodynamic effects.  Downsides; If used without paralytic - myoclonus. Though to have some adrenal suppression. Fentanyl Type: Opioid analgesic. Not traditional sedative. Benefits: There are many instances in emergency medicine in which sedation can be avoided by prioritizing proper analgesia. Fentanyl can even be used to maintain intubated patients without needing to keep them constantly sedated. Downsides: Respiratory depression. Patients may have tolerance. References Chawla N, Boateng A, Deshpande R. Procedural sedation in the ICU and emergency department. Curr Opin Anaesthesiol. 2017 Aug;30(4):507-512. doi: 10.1097/ACO.0000000000000487. PMID: 28562388. Keating GM. Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting. Drugs. 2015 Jul;75(10):1119-30. doi: 10.1007/s40265-015-0419-5. PMID: 26063213. Lundström S, Twycross R, Mihalyo M, Wilcock A. Propofol. J Pain Symptom Manage. 2010 Sep;40(3):466-70. doi: 10.1016/j.jpainsymman.2010.07.001. PMID: 20816571. Matchett G, Gasanova I, Riccio CA, Nasir D, Sunna MC, Bravenec BJ, Azizad O, Farrell B, Minhajuddin A, Stewart JW, Liang LW, Moon TS, Fox PE, Ebeling CG, Smith MN, Trousdale D, Ogunnaike BO; EvK Clinical Trial Collaborators. Etomidate versus ketamine for emergency endotracheal intubation: a randomized clinical trial. Intensive Care Med. 2022 Jan;48(1):78-91. doi: 10.1007/s00134-021-06577-x. Epub 2021 Dec 14. PMID: 34904190. Mihaljević S, Pavlović M, Reiner K, Ćaćić M. Therapeutic Mechanisms of Ketamine. Psychiatr Danub. 2020 Autumn-Winter;32(3-4):325-333. doi: 10.24869/psyd.2020.325. PMID: 33370729. Nakauchi C, Miyata M, Kamino S, Funato Y, Manabe M, Kojima A, Kawai Y, Uchida H, Fujino M, Boda H. Dexmedetomidine versus fentanyl for sedation in extremely preterm infants. Pediatr Int. 2023 Jan-Dec;65(1):e15581. doi: 10.1111/ped.15581. PMID: 37428855. Summarized by Jeffrey Olson MS2 | Edited by Jorge Chalit, OMSII  

Show notes at pharmacyjoe.com/episode865. In this episode, I’ll discuss predicting the success of dexmedetomidine as a sedative. The post 865: Predicting Success of Dexmedetomidine as a Sedative appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode865. In this episode, I’ll discuss predicting the success of dexmedetomidine as a sedative. The post 865: Predicting Success of Dexmedetomidine as a Sedative appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode853. In this episode, I’ll discuss how to predict hypotension from dexmedetomidine. The post 853: Can hypotension from dexmedetomidine be predicted? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode853. In this episode, I’ll discuss how to predict hypotension from dexmedetomidine. The post 853: Can hypotension from dexmedetomidine be predicted? appeared first on Pharmacy Joe.

In this episode, we delve into a new horizon in the management of acute agitation. We discuss dexmedetomidine, a drug that's been around since 1999, recently reformulated into a sublingual film and FDA approved for treating agitation associated with schizophrenia or bipolar I or II disorder. We explore the results from a recent randomized trial and its potential for transforming psychiatric care. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. Learn more about our membership here Earn 0.5 CMEs: Quick Take Vol. 47 Sublingual Dexmedetomidine for the Treatment of Acute Agitation in Adults With Schizophrenia or Schizoaffective Disorder: A Randomized Placebo-Controlled Trial

Are you using Precedex for alcohol withdrawal? Hear my take on why I don't like this idea, with evidence from a recently-published meta-analysis.Follow HERE!References:All references for Episode 94 are found on my Read by QxMD collectionSupport the showFind ER-Rx: - On Instagram: @ERRxPodcast - On the website: errxpodcast.com - On YouTube Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution, seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of, any medical institutions, educational facilities, or other healthcare programs.

Non invasive ventilation is steadily establishing itself as a crucial component of the critical care armoury.  While many patients can tolerate it, some require sedation. Wisam Al-Bassam is a staff specialist at Monash Medical center and Victorian Heart hospital.  Wisam is passionate about education and research, and his research interests include mechanical ventilation and sedation in ICU.  He joins Todd to talk about the role of dexmedetomidine in patients on non invasive ventilation in the ICUSee omnystudio.com/listener for privacy information.

Dr. Michael Lanspa chats with Dr. Yahya Shehabi about his article, "Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III)."

Show notes at pharmacyjoe.com/episode799. In this episode, I’ll discuss an article about intranasal dexmedetomidine for procedural sedation in the ED. The post Episode 800: Intranasal Dexmedetomidine for Procedural Sedation in the ED appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode799. In this episode, I’ll discuss an article about intranasal dexmedetomidine for procedural sedation in the ED. The post Episode 800: Intranasal Dexmedetomidine for Procedural Sedation in the ED appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode781. In this episode, I'll discuss an article about clinical outcomes when dexmedetomidine is given to patients who have agitation from drug overdose or withdrawal. The post 781: Do Patients Who Have Agitation From Drug Overdose or Withdrawal Improve When Dexmedetomidine is Given? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode781. In this episode, I ll discuss an article about clinical outcomes when dexmedetomidine is given to patients who have agitation from drug overdose or withdrawal. The post 781: Do Patients Who Have Agitation From Drug Overdose or Withdrawal Improve When Dexmedetomidine is Given? appeared first on Pharmacy Joe.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Yahya Shehabi. They discuss sedation with dexmedetomidine and propofol in critically ill patients. Dr. Shehabi is Professor of Medicine at Monash University (Australia).

In this episode, we discuss the biphasic effects of dexmedetomidine on the cardiovascular system and how we manage the decreased heart rates associated with this drug.  We review a 2021 article from Veterinary Anaesthesia and Analgesia regarding lidocaine as a treatment for dexmedetomidine-induced bradycardia.    Link to the journal article: shorturl.at/ioQW4

In der neuesten Folge des HAINS Talk Journal Clubs geht es um ein aktuelles und pikantes Thema

In today's VETgirl online veterinary continuing education podcast, we interview Dr. Marc Seitz, DVM, DACVR, DABVP (Canine and Feline Practice), Assistant Clinical Professor of Diagnostic Imaging at Mississippi State University on a recent study he published entitled "Sedation with dexmedetomidine is associated with transient gallbladder wall thickening and peritoneal effusion in some dogs undergoing abdominal ultrasonography." If you're doing point-of-care ultrasounds (AKA FAST ultrasounds) on your patients sedated with dexmedetomidine, you'll need to be on the look out for gallbladder edema or the "HALO" sign. Tune in to learn all the important differentials you should be keeping in mind when you see the HALO sign on veterinary ultrasound!

Most of this answer is in PD

The post Episode 79. Stop the flex with Precedex: The Use of Dexmedetomidine for Procedural Sedation appeared first on The Pharm So Hard Podcast.

Show notes at pharmacyjoe.com/episode715. In this episode, I'll discuss 4 alternative routes of administration for dexmedetomidine. The post 715: Four Alternative routes of administration for dexmedetomidine appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode715. In this episode, I ll discuss 4 alternative routes of administration for dexmedetomidine. The post 715: Four Alternative routes of administration for dexmedetomidine appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode713. In this episode, I'll discuss whether there is a benefit from switching to dexmedetomidine when sedation is started with midazolam. The post 713: Is there a benefit from switching to dexmedetomidine when sedation is started with midazolam? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode713. In this episode, I ll discuss whether there is a benefit from switching to dexmedetomidine when sedation is started with midazolam. The post 713: Is there a benefit from switching to dexmedetomidine when sedation is started with midazolam? appeared first on Pharmacy Joe.

We talk to Dr Tom Jackson about his article in Archives of Disease in Childhood looking at the use of Dexmedetomidine as a sedative agent fro children undergoing MRI scans in a district general hospital. Is it better the NICE recommended medications? Article can be found here: https://adc.bmj.com/content/early/2022/03/10/archdischild-2021-322734

Dexmedetomidine and temperature changes is this BJANcast's main theme with Dr. Felipe Ferreira da Cruz, Unifesp. #citeBJAN #joinBJAN #BJANcast Social Networks: bjan-sba.org Instagram Facebook LinkedIn Twitter

Editor's Summary by Kristin Walter, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the February 22, 2022 issue.

February 2018 Dexmedetomidine for Post-Craniotomy Pain by SNACC

In this first episode of the Society for Pediatric Sedation (SPS) Podcast, we will be discussing the use of intranasal medication in procedural sedation for children. We will be joined by Dr. Carmen Sulton, the Assistant Professor of Pediatrics at Emory University School of Medicine and Director of Children Sedation Services at Egleston campus in Atlanta. Dr. Sulton is well published in the field of pediatric procedural sedation including a recent paper on the use of intranasal Dexmedetomidine published in Pediatric Emergency Care in 2020. The paper uses patient outcomes data from the Pediatric Sedation Research Consortium database, the research arm of the Society for Pediatric Sedation.In our case today, we have a five months old infant who requires an MRI of his brain. The patient is an ex-32 week premature infant with a history of difficult IV access. There's no history of upper respiratory tract infection, no snoring, heart disease, or any medication allergy in this infant. The MRI is needed for a focal seizure that occured two weeks ago and the patient doesn't require an IV since this is not a contrasted MRI. Dr. Sulton will generously share with us why intranasal medications are needed in procedural sedation and so much more, so don't miss out if this is a topic of interest for you.Meet your hosts:Pradip Kamat, MD, MBA - Associate Professor of Pediatrics and Critical Care Physician at Emory University School of Medicine and Children's Healthcare of Atlanta/Egleston.Anne Stormorken, MD - Professor of Pediatrics and Critical Care Physician at UH Rainbow Babies and Children's Hospital and Case Western Reserve School of Medicine of Cleveland, OH.Show HighlightsDiving into how intranasal medications work (01:58)Circumstances where intranasal medications must not be used for procedural sedation (04:35)How she uses Dexmedetomidine and Midazolam (06:28)Research findings on the success rate with the use of intranasal medications (09:14)Other medications that can be used intranasally for procedural sedation (11:42)Optimizing the efficacy of intranasal medications when delivering them (12:09)Giving IV sedation where there is intranasal medication failure (13:23)Large dataset studies that support the successful use of intranasal medications in procedural sedation (14:23)Additional ResourcesThe Use of Intranasal Dexmedetomidine and Midazolam for Sedated Magnetic Resonance Imaging in Children

Show notes at pharmacyjoe.com/episode622. In this episode, I'll discuss early dexmedetomidine use and body temperature elevation. . The post 622: Early dexmedetomidine use and body temperature elevation appeared first on Pharmacy Joe.

Narrator: Dr. Deepali Garg Trainee Engagement Committee Resident in Anesthesiology, University of Iowa

Margaret Parker, MD, MCCM, speaks with Mary Jo C. Grant, APRN, PhD, about the article, Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure, published in the December 2016 issue of Pediatric Critical Care Medicine.

This week Kieran and Dr. Fraser Pollard, a Family Physician in Trenton, Ontario, discuss two studies: Using long acting beta agonists (LABAs) safely and appropriately in the management of asthma is widely debated, with evidence suggesting a potential risk of serious asthma-related events associated with the use of LABAs. But is the potential risk warranted? ...The post Dazed and Confused – Dexmedetomidine for the Prevention of Delirium and the Safety of LABAs in Asthma appeared first on Healthy Debate.

This week Kieran and Dr. Fraser Pollard, a Family Physician in Trenton, Ontario, discuss two studies: Using long acting beta agonists (LABAs) safely and appropriately in the management of asthma is widely debated, with evidence suggesting a potential risk of serious asthma-related events associated with the use of LABAs. But is the potential risk warranted? ... The post Dazed and Confused – Dexmedetomidine for the Prevention of Delirium and the Safety of LABAs in Asthma appeared first on Healthy Debate.