Podcasts about Administration

Watch The X22 Report On Video No videos found (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:17532056201798502,size:[0, 0],id:"ld-9437-3289"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="https://cdn2.decide.dev/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs");pt> Click On Picture To See Larger PictureGermany has followed the [CB]/[WEF] green new scam and now the manufacturing jobs imploding. Germany will struggle in 2026. The debt in the US is made up of fraud, its most likely in the trillions. There a silver storm approaching and the gap between gold and silver will close as the [CB] loses control. Sound money is the only way. The [DS] is now panicking, their money laundering scheme is being exposed, the people now know that they funnel money via NGO’s and shell companies. This is bigger than anyone could ever imagine. We are in the exposure and investigative phase, Next is the cleanup, then justice. To bring down the entire corrupt system, it must be done right, it must carry weight, we must follow the rule of law, good thinks sometimes take time. Economy (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:18510697282300316,size:[0, 0],id:"ld-8599-9832"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="https://cdn2.decide.dev/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs"); Half of Germany's Manufacturing Sectors Anticipate Significant Layoffs and Job Losses in 2026   Germany is the epicenter of the European Union's overall goal to chase the green energy agenda. For the past several years Germany has been deconstructing their fossil fuel energy production and replacing it with far more expensive alternatives.  This has led to large increases in overall energy prices, and downstream increases in manufacturing costs. The consequences have been snowballing throughout 2025, while cheap competitive alternatives coming into the EU from China have compounded their problem.  Recently a survey of major industries was conducted in Germany to determine the forecast for 2026, the results are not good. Approximately half of the industrial sectors in Germany are anticipating job losses, cuts or layoffs this year. 22 out of 46 business associations are preparing to downsize their labor force.  Only 9 of the 46 are expected to increase hiring.   Job losses are expected in auto manufacturing, the textile sector, wood and paper fabrication.  Job gains are expected in aerospace, shipbuilding and defense production – i.e. the war machinery. When the largest and most developed industrial economy in Europe is pinning its economic survival on war machinery, a particular momentum is created.  It is never a good outcome for Europe when Germany becomes reliant on war to maintain employment. Source: theconservativetreehouse.com https://twitter.com/stats_feed/status/2005654716462538992?s=20 2009 – $12T 2010 – $13.6T 2011 – $14.8T 2012 – $16.1T 2013 – $16.7T 2014 – $17.8T 2015 – $18.2T 2016 – $19.6T 2017 – $20.2T 2018 – $21.5T 2019 – $22.7T 2020 – $27T 2021 – $28.4T 2022 – $30.9T 2023 – $33.2T 2024 – $35.3T 2025 – $38.5T https://twitter.com/StephenM/status/2005494075793735925?s=20  self-loathing, self-denigration and the redistribution of our national resources to the states and peoples of the undeveloped world. https://twitter.com/profstonge/status/2005633652852437451?s=20 Political/Rights Trump-Kennedy Center Hits Jazz Star with $1M Lawsuit For Backing Out Of Christmas Eve Show Redd, a drummer and vibraphone player who has performed with legends including Dizzy Gillespie and Ray Brown, had hosted the Christmas Eve Jazz Jam at the Kennedy Center since 2006. He took over the tradition from bassist William “Keter” Betts and maintained it for nearly two decades. This year marked an abrupt departure from that longstanding commitment. “When I saw the name change on the Kennedy Center website and then hours later on the building, I chose to cancel our concert,” Redd told The Associated Press. The Trump-Kennedy Center is pursuing a $1 million lawsuit against jazz musician Chuck Redd after he withdrew from his annual Christmas Eve concert at the last minute, citing the recent addition of President Trump’s name to the venue.  Source: zerohedge.com https://twitter.com/libsoftiktok/status/2005398115030024201?s=20 DOGE Geopolitical Trump Administration Slashes UN “Humanitarian” Funding Pledge  The United States announced a $2 billion pledge for United Nations humanitarian aid programs on Monday, marking a sharp reduction from previous years as the Trump administration pushes for major reforms in global aid spending. This pledge represents a fraction of historical U.S. contributions, which have reached up to $17 billion in recent years, with voluntary funding often in the $8-10 billion range. Administration officials describe the amount as sufficient to keep America as the world's top humanitarian donor while demanding greater efficiency from UN agencies. The funding will flow through an umbrella mechanism controlled by the UN's Office for the Coordination of Humanitarian Affairs (OCHA), allowing targeted distribution to specific crises and countries. Initial priorities include 17 nations such as Bangladesh, Congo, Haiti, Syria, and Ukraine. Notably absent from the list are Afghanistan and the Palestinian territories, with officials stating Gaza aid will tie into ongoing peace efforts. Source: discernreport.com  War/Peace Did US Land Strikes On Venezuela Begin Last Week & No One Knew It? President Trump on Friday in a radio interview disclosed something which missed the attention of the US and global media. He let slip that a large land site had been knocked out by a strike from US forces in the Caribbean – however without specifying which country was hit (whether Venezuela or perhaps Colombia). o  According to the full remarks in context, the president said: “But every time I knock out a boat, we save 25,000 American lives. It’s very simple. And what’s happening is they’re having a hard time employment-wise, they can’t get anybody. And we just talked out, I don’t know if you read or you saw, they [Venezuela] have a big plant or a big facility where the ships come from. Two nights ago, we knocked that out. So we hit them very hard. But drugs are down over 97 percent. Can you believe it?” Some unnamed American officials suggested to the New York Times that the Commander-in-Chief was referring to a drug facility in Venezuela: Trump did not name the location of the facility, though American officials told the New York Times that the president was referring to a drug facility in Venezuela that was eliminated. The president's comment is the only report of such an attack. No other Latin American government, including Venezuela, has disclosed a strike of this sort. : Source: zerohedge.com  Zelensky Wants 50-Year(!) Security Guarantee From Trump A major point of disagreement remains security guarantees. Ukraine has been pushing maximalist demands for something akin to NATO Article 5 protections. It would be like getting all the benefits of being in NATO but without being a formal member of the Western military alliance. The Ukrainian side has revealed that President Trump had offered security guarantees for 15 years following a peaceful settlement, but Zelensky considered this much too short to protect from future potential Russian aggression. But in classic Zelensky fashion, he wants way more than this. Also, maximalist demands are something that European leaders have backed him on all along – and they may have even put him up to. According to The Wall Street Journal: Kyiv had asked for security guarantees to last up to 50 years after the end of the conflict during weekend discussions. In the documents currently being discussed, the U.S. offered a 15-year guarantee with the possibility of extension, Zelensky said in audio messages to journalists on Monday.   Source: zerohedge.com  Russia accuses Ukraine of military attack on Putin’s residence: ‘state terrorism’   Russia is promising retaliation against Ukraine for an alleged military attack on President Vladimir Putin’s residence in the northern Russia area of Novgorod, which Ukrainian President Volodymyr Zelensky deemed a lie intended to undermine peace talks, Reuters reports. . Russian Foreign Minister Sergei Lavrov said Monday that Russian air defenses destroyed all 91 long-range drones targeting Putin’s residence and that no one was injured and no damage reported. “Such reckless actions,” which Lavrov deemed “state terrorism,” will be answered with retaliatory strikes on targets in Ukraine, he said. Ukrainian President Zelensky says it’s a false claim intended to undermine peace talks  . Source: justthenews.com https://twitter.com/AutistDivision/status/2005463473006801341?s=20  geo-political territories forever. And lets be honest, they couldn’t get them back under any circumstances again. Medical/False Flags [DS] Agenda https://twitter.com/amuse/status/2005334470799565113?s=20   LAFD Battalion Chief Kenneth Cook rejected the final Palisades fire report after LAFD leadership removed critical findings tied to preparation failures before Jan. 7. Drafts obtained through public records show staffing violations, delayed assignments & ignored wind warnings were scrubbed from the final version. The report meant to save lives became a political shield. As a side note, New York City is setting themselves up for the same problem... https://twitter.com/amuse/status/2005608785990262859?s=20 https://twitter.com/EricLDaugh/status/2005622039999062219?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E2005622039999062219%7Ctwgr%5E11dcdb289244b9644ea68d25359a18f753233f5d%7Ctwcon%5Es1_c10&ref_url=https%3A%2F%2Fwww.thegatewaypundit.com%2F2025%2F12%2Fsomali-fraud-scandal-expands-as-lawyer-exposes-damning%2F   pushing for that in every single state!” “The state will, as long as the doctor has approved it, continue to pay you. It could be for 10 hours, 12 hours, up to 24 when it’s critical care.” “So you could sit at home without caring for an elderly parent who really doesn’t need it, make about $75,000 to $90,000 a year. Now you add two parents, that’s $180,000. Now you add your in-laws $250,000.” “You continue to add this and you wonder what are the services being provided? So a lot of providers came and said fraud is occurring because we said we weren’t going to rubber stamp this paperwork.” “So they went to other providers, their home health care networks saying we’ll make it worth your while. Well, sounds like a kickback to me.” “So we really need to investigate the Medicaid system and how much it’s increased since the Somalian population came and who really needs critical care because that’s meant for our disabled, our elderly and people who really need it, not to just live off our system.” “And that’s what’s happening in Ohio. I think it’s ridiculous. I think it’s despicable, but authorities are now looking at it from the Attorney General’s office to the U.S. Attorney’s office.” “I flagged them all because this is Ohio tax dollars and we have to take it seriously. I’m tired of people telling me, well, this is the way it’s always been. It’s subjective and we can’t really check. No, you can.” https://twitter.com/ArthurMacwaters/status/2005324862756127166?s=20   this not instant jail?! Like this is electoral fraud on top of Medicare fraud How is this not front page of every newspaper?! https://twitter.com/elonmusk/status/2005535693918138533?s=20 https://twitter.com/amuse/status/2005657030111932568?s=20   was unanimously convicted by a jury only to have Judge Sarah West vacate the verdict. In two separate cases to other judges dismissed the cases against his wife and his brother. $7.2 million is gone and no one is being held accountable. This story is being repeated across Minnesota to the tune of more than $8 billion so far. Somali criminals in Minnesota have stolen more than Somalia’s GDP from American taxpayers. Why won’t Democrat judges hold them accountable? https://twitter.com/elonmusk/status/2005496793279439182?s=20 https://twitter.com/JoeLang51440671/status/2005476678261461399?s=20   broke to being worth up to $30 million in just a year — as a massive, up to $9 billion fraud scheme involving the Somali community in her district unfolded right under her nose in Minnesota.” $9 billion in fraud happened in her district? Can I ask the question? How many Somali daycares did Ilhan Omar own? “Close to 90 people have been charged so far, including at least three with direct ties to the lefty Squad member, though she has not been charged.” https://nypost.com/2025/12/27/us-news/ilhan-omars-hubbys-30m-firm-quietly-scrubs-names-from-website-as-squad-member-faces-mounting-questions-on-sudden-wealth-amid-minnesota-welfare-fraud/ That's going to change. Have we looked into the wealth of the brother she married? I wonder if he owns some Somali daycares in Minnesota? Tick Tock!! https://twitter.com/libsoftiktok/status/2005657804301013272?s=20  , the Google business listing for this center showed the phone number 651-201-3400, which is the official public contact line for the Office of Governor Tim Walz and Lt. Governor Peggy Flanagan    https://twitter.com/JoeLang51440671/status/2005329284785647715?s=20   significant investments in pre-K for four-year-olds as well as other early learning programs serving children and families birth-to-school entry. This year he focused on the country's youngest children and their families' need for high-quality child care.” The Obama administration was a gigantic money laundering operation. “The President explained the need in last Tuesday's address stating, “In today's economy, when having both parents in the workforce is an economic necessity for many families, we need affordable, high quality childcare more than ever.” “But the child care tax credit isn't all the President proposed.” “He would also significantly expand the Child Care and Development Fund(CCDF), a child care subsidy for low- and moderate-income families authorized under the Child Care Block Development Grant (CCDBG) Act. (CCDBG was reauthorized last year after 18 years.) By 2025, the proposed expansion would increase the reach of CCDF to an additional one million children, under four-years-old.” Taxpayers subsidies and grants for “childcare.” “The last part of the President's proposal, in typical Obama Administration-style, is a competitive grant that would promote innovation in the child care system. The proposed grants– totaling $100 million– would allow states to create pilot programs to determine the best ways to provide child care to vulnerable populations, including children with disabilities, parents who work non-traditional hours, and families who have difficulty finding high-quality child care.” https://newamerica.org/education-policy/edcentral/presidents-child-care-plan/ Taxpayers “grants” totaling $100 million (for starters) to be given to “vulnerable populations.” Can you say “Somali?” Taxpayers funding of “childcare,” was a “necessity” for the funding of the democrat party. The Somali community was always a hub of this “childcare” theft of taxpayers money. It was set up this way on purpose. A Somali community, governed by Somali's and protected by the democrat party. The Somali's were being brought into this country starting with the George W. Bush's presidency. But Obama began accelerating the number of refugees from Somalia along with other Muslim countries. Here's just the last year under Obama. “A total of 38,901 Muslim refugees entered the U.S. in fiscal year 2016, making up almost half (46%) of the nearly 85,000 refugees who entered the country in that period, according to a Pew Research Center analysis of data from the State Department's Refugee Processing Center. That means the U.S. has admitted the highest number of Muslim refugees of any year since data on self-reported religious affiliations first became publicly available in 2002.” “Just two countries – Syria (12,486) and Somalia (9,012) – were the source of more than half of fiscal 2016's Muslim refugees. The rest are from Iraq (7,853), Burma (Myanmar) (3,145), Afghanistan (2,664) and other countries (3,741).” https://pewresearch.org/short-reads/2016/10/05/u-s-admits-record-number-of-muslim-refugees-in-2016/ Obama was an installed puppet of Prince Alwaleed and was doing his bidding. Obama filled his administration with people tied to the Muslim Brotherhood, who were implementing their “civilization jihad.” These communities began electing corrupt representatives like Ilhan Omar. Infiltration not invasion. Taxpayers money was funneled into these communities through “childcare grants” and other “welfare programs,” in order to fund the democrat party. Minnesota is just the “doorway” into a much larger nationwide fraud scheme to fund the democrat party. A magnifying glass is about to be put on ALL state welfare programs that are receiving “federal funding.” These grants and benefits handed out to these crooks, are now the doorway to expose and bring them all to an end. BOOMERANG! https://twitter.com/everytime_11/status/2004718928686350461?s=20 https://twitter.com/EndWokeness/status/2005651406985036272?s=20 Tim Walz's Office Responds with an Outrageous Falsehood After Journalist Nick Shirley Exposes Fraud of the Century in Minnesota “The governor has worked for years to crack down on fraud and ask the state legislature for more authority to take aggressive action,” a spokesperson for Walz told Fox News. “He has strengthened oversight – including launching investigations into these specific facilities, one of which was already closed,” the spokesperson added. “(He) hired an outside firm to audit payments to high-risk programs, shut down the Housing Stabilization Services program entirely, announced a new statewide program integrity director, and supported criminal prosecutions.” Walz previously called Shirley and others who have questioned his handling of the scandal “white supremacists.” Walz's team wants the public to believe that not only does the governor have no involvement in the scandal, but he has also been a leading advocate against this corruption. They must think that every day Americans have the same >IQ as Somali citizens.   Source: thegatewaypundit.com https://twitter.com/ElectionWiz/status/2005427571861909629?s=20 https://twitter.com/KevinKileyCA/status/2005329670083145745?s=20 Back on June 24, 2025. about 31% of applications to California’s 116 community colleges were deemed likely fraudulent by the chancellor’s office—equating to over 1.2 million fake applications. These were mostly detected and blocked before enrollment or aid disbursement, but some fraud succeeded, costing millions in stolen financial aid (around $11 million total in 2024, a small fraction of the billions distributed overall).The piece discusses ongoing efforts to combat the issue, like improved detection tools, identity verification, and a proposed $10 application fee to deter bots and scammers targeting the free-application, open-access system.  https://twitter.com/CynicalPublius/status/2005388876807057913?s=20 President Trump's Plan https://twitter.com/stats_feed/status/2005654716462538992?s=20 2009 – $12T 2010 – $13.6T 2011 – $14.8T 2012 – $16.1T 2013 – $16.7T 2014 – $17.8T 2015 – $18.2T 2016 – $19.6T 2017 – $20.2T 2018 – $21.5T 2019 – $22.7T 2020 – $27T 2021 – $28.4T 2022 – $30.9T 2023 – $33.2T 2024 – $35.3T 2025 – $38.5T https://twitter.com/4nt1p4tt3rn/status/2005345471674388575?s=20  deniability to the federal and state governments, and allow them to funnel money into the NGOs to do what the governments either don’t want to (due to optics) or can’t (due to legal constraints) do. They are quite literally dismantling the United States of America, and they’re doing it with YOUR money. Quite literally money taken out of your pockets. Food taken out of your children’s mouths. They’re directly or indirectly responsible for: * the massive invasion of this country by illegals * the high cost of healthcare * the shortage and high price of homes * the shortage and high price of unimproved land * the high cost of food and other goods * the high taxes you’re forced to pay * the skyrocketing national debt * the skyrocketing federal deficit * DEI and the elimination of qualified American workers from jobs * deaths of Americans on our roadways * the broken “justice” system In other words, literally everything everyone’s complaining about. https://twitter.com/911NewsBreaks/status/2005660846848958944?s=20   planning to livestream a racially motivated extremist attack with pipe b-mbs and g-ns. https://twitter.com/HarmeetKDhillon/status/2005444604624028029?s=20   year later as special counsel in November … statute runs on his obvious shenanigans late 2027 * Democrats in Congress and those in the states colluding with Biden WH hide their behavior, some of which STILLL HASN'T come to light! Statute runs on this five years after their concealed behavior is known to the government. This means the statute could run in the next administration. STOP POSTING CLICKBAIT BS!!! You are being used! https://twitter.com/HarmeetKDhillon/status/2005446072634872033?s=20 https://twitter.com/grok/status/2005427970681217334?s=20   to Jan. 6, 2021/2026. Specific cases vary by act. ‘Ten-year stain:' Bondi asks prosecutors to probe Obama-Biden lawfare as criminal conspiracy FBI Director Kash Patel penned a memo predicating an investigation looking at the weaponization of intelligence and law-enforcement powers dating to the Russia collusion case as an ongoing conspiracy. Attorney General Pam Bondi   asked the prosecutors to investigate the Obama-Biden era of lawfare as an ongoing election-meddling conspiracy that protected Democrats from criminal investigation and infringed the civil rights of Republicans like President Donald Trump and his supporters. An “ongoing conspiracy” and the statute of limitations Such an approach allows prosecutors to charge defendants with alleged crimes outside the statute of limitations because they were connected to an ongoing conspiracy, much like those cases brought against the mafia and drug cartels. “At my direction, our U.S. Attorneys and federal agents are actively investigating instances of government weaponization nationwide,” Bondi said. “This is a ten-year stain on the country committed by high-ranking officials against the American people. Source: justthenews.com https://twitter.com/WarClandestine/status/2005434508124782615?s=20   to be deported. They opposed the One Big Beautiful Bill because it funds ICE/US MIL, and they know Trump is going to invoke the Insurrection Act to deploy troops to their cities to assist ICE in deporting the illegals. If the Dems can't cheat in elections, they lose access to our tax dollars, and thus they lose all their power. They never cared about diversity, equality, equity, inclusion, immigration or any of that shit. It was all just a transaction. Everything they say and do is just a means to justify their treasonous scheme to steal our tax dollars. That's why it's so important to nuke the filibuster, pass the Save Act, invoke the Insurrection Act, deport all the illegals, and arrest everyone involved. If we don't, the Dems will take complete control, we will become a one-party State, and they will eventually phase us out via mass immigration. That's why the Dems have been trying to destroy, obstruct, and kill Trump, ever since he came down the escalator. Because they knew that he knew about all this, and is on a mission to stop it. The American People are being replaced, and the Democrats are directly responsible for it. This is the battle for the Republic. 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Every year, our family practices a simple but meaningful tradition. Each of us chooses a single word to guide the year ahead. Not as a resolution, but as a lens. A word to pay attention to, to live with, and to let shape us over time.Today, I am joined by my wife, Jana, our son Seth, and daughter Megan. Together, we look back on the past twelve months and reflect on how these words played out in real life. Not theory. Not polish. Just honest stories of growth, tension, and becoming.To Order Doug's Books: The Resiliency Quest,Mad About Us Visit Doug's Website: https://www.dougmckinley.com/ Receive a Free Leadership Resource: Leadership Guide 

As always, we were fortunate to have some amazing guests join us this year on The Imprint Weekly Podcast. In this episode we feature clips of 12 great interviews from 2025. If you enjoy this podcast, or the great work our reporters do at The Imprint andFostering Families Today, and the work that our Youth Voices Rising team does,please consider making a donation. And if you do so this month, duringNewsmatch, your donation will get doubled!Fostering Media Connections is very lucky to have some terrific philanthropic supporters, advertisers and sponsors, and subscribers to our business and policy section that help make this organization go. But we really cannot do it without donors like you who read our stuff, listen to our podcasts and attend our onlineevents. There are tons of really great nonprofit, independent news outlets to support out there, and we hope you consider us one of them. To give today it's easy! Visit www.imprintnews.org/donate.Liz Ryan, former administrator, U.S. Office of Juvenile Justice and Delinquency PreventionLinda Spears, CEO, Child Welfare League of AmericaKelley Fong, assistant professor of sociology, University of California, IrvineAmy Harfeld, national policy director and senior staff attorney, Children'sAdvocacy InstituteSacha Klein, associate professor, Michigan State University School of Social WorkAlex Briscoe, co-founder, Public Works AllianceBrandon Nichols, director, Los Angeles Department of Children and Family ServicesBarissa Ford, director of community outreach and engagement, Youth In NeedClaudia Rowe, editorial writer, Seattle Times, author of Wards of the StateGretchen Sisson, qualitative sociologist, University of California, San Francisco,author of RelinquishedVinny Schiraldi, visiting fellow, Pinkerton FoundationAlex Adams, assistant secretary for family support, Administration for Children and Families

It's the first day of fireworks sales on Oahu. We take a look at the crowds and what you need to know to celebrate safely. Family members reveal new details about the relationship between Amber Jackson and the man accused of killing her 15 years ago. And Hawaiian Airlines is warning of a ticketing glitch that will likely create longer security lines, on what's already expected to be one of the busiest travel weekends of the year. See omnystudio.com/listener for privacy information.

After more than two months, a strike at Kapiolani Medical Center for Women and Children is over. With a new contract, when will hundreds of Hawaii Teamsters and Allied Workers Local 996 workers return? We also have new details about the relationship between a suspected killer and his alleged victim in a 15-year-old cold case on Kauai. And a software glitch could slow down security lines at the airport. What you need to know if you're headed to the airport.See omnystudio.com/listener for privacy information.

A long-running strike at a major Honolulu hospital is now over. What workers and hospital leaders are saying after a new agreement is reached. A Hawaii Kai homicide case is moving forward in court. The charges a man now faces and what he told a judge. And many Kapilina Beach Homes residents say their electricity bills have more than doubled, with some reporting charges of over one thousand dollars.See omnystudio.com/listener for privacy information.

【欢迎订阅】每天早上5:30，准时更新。【阅读原文】标题：T Administration Declares Foreign-Made Drones a Security Threat正文：The Trump administration announced on Monday that all foreign-made drones and their components posed “unacceptable risks to the national security of the United States” and would be put on a federal blacklist of equipment makers prohibited from selling their goods freely in the country. Americans won't be able to buy new models from DJI, the Chinese maker of most of the world's drones. But U.S. pilots can keep the drones they have.知识点：Administration n. /ədˌmɪnɪˈstreɪʃn/The management of public affairs; government. 政府；行政当局The current administration is focusing on economic reform. (现任政府正专注于经济改革。)She has a high position in the school administration. (她在学校行政管理部门担任要职。)获取外刊的完整原文以及精讲笔记，请关注微信公众号「早安英文」，回复“外刊”即可。更多有意思的英语干货等着你！【节目介绍】《早安英文-每日外刊精读》，带你精读最新外刊，了解国际最热事件：分析语法结构，拆解长难句，最接地气的翻译，还有重点词汇讲解。所有选题均来自于《经济学人》《纽约时报》《华尔街日报》《华盛顿邮报》《大西洋月刊》《科学杂志》《国家地理》等国际一线外刊。【适合谁听】1、关注时事热点新闻，想要学习最新最潮流英文表达的英文学习者2、任何想通过地道英文提高听、说、读、写能力的英文学习者3、想快速掌握表达，有出国学习和旅游计划的英语爱好者4、参加各类英语考试的应试者（如大学英语四六级、托福雅思、考研等）【你将获得】1、超过1000篇外刊精读课程，拓展丰富语言表达和文化背景2、逐词、逐句精确讲解，系统掌握英语词汇、听力、阅读和语法3、每期内附学习笔记，包含全文注释、长难句解析、疑难语法点等，帮助扫除阅读障碍。

Ce sujet vous a particulièrement captivé cette année, sans doute parce qu'il touche au cœur même de l'indépendance technologique.Alors, si pendant les fêtes vous vous retrouvez à devoir expliquer à votre famille pourquoi il existe des alternatives aux géants américains du numérique, ou si l'on vous demande de dépanner le PC familial, vous pourrez désormais citer cet exemple frappant.Direction l'Allemagne, où une administration entière a prouvé qu'il était possible de couper le cordon avec Microsoft.Un chantier informatique colossalConcrètement, nous parlons ici du Land du Schleswig-Holstein. Cette région allemande a finalisé cette année un chantier informatique colossal en abandonnant totalement ses systèmes de messagerie et d'agenda propriétaires.Ils ont remplacé le couple bien connu Microsoft Exchange et Outlook par des solutions Open Source, à savoir Open-Xchange et Mozilla Thunderbird.Ce n'est pas une simple expérimentation de laboratoire. La bascule concerne l'ensemble de l'appareil d'État, de la chancellerie aux ministères, en passant par la police et la justice. L'objectif affiché est sans équivoque. Il faut garantir la souveraineté numérique et ne plus dépendre des décisions d'une seule grande entreprise technologique.Pour bien saisir la prouesse technique, il faut se pencher sur les chiffres, car ils donnent le vertige.La migration a duré six mois et a impliqué le transfert de plus de 40 000 boîtes aux lettres électroniquesLa migration a duré six mois et a impliqué le transfert de plus de 40 000 boîtes aux lettres électroniques. Au total, ce sont plus de 100 millions de messages et d'entrées d'agenda qui ont été migrés vers ce nouvel environnement libre.Les autorités locales qualifient elles-mêmes ce projet de pionnier, affirmant qu'il existe très peu de précédents de cette ampleur dans le monde. C'est d'ailleurs la suite logique d'une stratégie entamée l'année précédente avec le déploiement de LibreOffice pour remplacer la suite bureautique traditionnelle.Le logiciel libre est désormais une alternative crédible et robusteAu-delà de l'exploit technique, l'impact pour les décideurs informatiques et les administrations européennes est majeur. Le Schleswig-Holstein se positionne désormais comme un modèle exportable, prêt à partager son expertise, de l'analyse des données à la surveillance des centres de données.Ce mouvement s'inscrit dans une tendance de fond en Europe, rejoignant des initiatives similaires observées dans l'armée autrichienne ou, plus près de nous, dans la ville de Lyon.Pour les DSI, la leçon est claire : le logiciel libre est désormais une alternative crédible et robuste pour réduire les dépendances monopolistiques et garder la maîtrise réelle des données citoyens et entreprises.Le ZD Tech est sur toutes les plateformes de podcast ! Abonnez-vous !Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

And just like that, 2025 is coming to a close. On this week's On the Media, hear a tour of a 12-month news blitz, from AI to the Pentagon press room to the reshaping of legacy outlets. Plus, what we can expect from the year to come.[02:33] This week, Brooke and Micah review how legacy outlets made big changes  in the wake of Donald Trump's inauguration this year. Featuring: Oliver Darcy, author of the newsletter Status.[11:53] Brooke and Micah take stock of the administration's embrace of far right online personalities – in the White House and in the press room. Plus, a review of the wreckage DOGE has left in its wake, and Trump's crackdown on free speech.Featuring: Vittoria Elliott, senior reporter at Wired, Ryan J. Reilly, senior justice reporter for NBC News, Brandy Zadrozny, senior reporter at MS NOW, Anna Merlan, senior reporter for Mother Jones, Corey Robin, professor of political science at Brooklyn College.[37:38] Brooke and Micah review how the press covered the deployment of the national guard; the aftermath of Charlie Kirk's murder; and the ongoing turmoil at CBS. Plus, how to steel ourselves for the year ahead.Featuring: Jamison Foser, media critic and author of the newsletter Finding Gravity, and Jamelle Bouie, columnist for The New York Times.  On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.

"They [monoclonal antibodies] are able to cause tumor cell death by binding to and blocking to necessary growth factor signaling pathways for tumor cell survival. That's going to be dependent on the target of the antibody, but I'll give an example of epidermal growth factor, or EGFR. This is overexpressed in several different kinds of cancers where activation of this growth factor increases the amount of proliferation and migration of cancer cells. So, if we bind to it and block to it, then that would help halt these pathways and stop cancer cell growth," Carissa Ganihong, PharmD, BCOP, oncology and bone marrow transplantation clinical pharmacist at Hackensack University Medical Center in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about monoclonal antibodies. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) (including 45 minutes of pharmacotherapeutic content) by listening to the full recording and completing an evaluation at courses.ons.org by December 26, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge in the history of, the mechanism of action of, and the use of monoclonal antibodies in the treatment of cancer.  Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 383: Pharmacology 101: Bispecific Antibodies Episode 375: Pharmacology 101: VEGF Inhibitors Episode 338: High-Volume Subcutaneous Injections: The Oncology Nurse's Role Episode 283: Desensitization Strategies to Reintroduce Treatment After an Infusion-Related Reaction Episode 275: Bispecific Monoclonal Antibodies in Hematologic Cancers and Solid Tumors ONS Voice articles: An Oncology Nursing Overview of Biosimilars Make Subcutaneous Administration More Comfortable for Your Patients Oncology Nurses' Role in Translating Biomarker Testing Results Reduce Chair Time by as Much as 16 Minutes by Priming IVs With Drug Shorter Administration Times Still Require High-Acuity Care The Names of Targeted Therapies Give Clues to How They Work ONS Voice drug reference sheets: Datopotamab deruxtecan-dlnk Enfortumab vedotin Margetuximab-cmkb Mirvetuximab soravtansine-gynx Nivolumab and hyaluronidase-nvhy Nivolumab and relatlimab-rmbw Pembrolizumab and berahyaluronidase alfa-pmph Retifanlimab-dlwr ONS book: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) ONS course: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ Clinical Journal of Oncology Nursing articles: Bolusing IV Administration Sets With Monoclonal Antibodies Reduces Cost and Chair Time: A Randomized Controlled Trial Management of Immunotherapy Infusion Reactions Nurse-Led Grading of Antineoplastic Infusion-Related Reactions: A Call to Action Safety and Adverse Event Management of VEGFR-TKIs in Patients With Metastatic Renal Cell Carcinoma Oncology Nursing Forum articles: Administration of Subcutaneous Monoclonal Antibodies in Patients With Cancer Depressive Symptoms and Quality of Life Associated With the Use of Monoclonal Antibodies in Breast Cancer Treatment ONS huddle cards: Bispecifics Checkpoint Inhibitors Monoclonal Antibodies Other ONS resources: Biomarker Database Bispecific Antibodies video Patient Education Sheets Antibodies article: A Comprehensive Review About the Use of Monoclonal Antibodies in Cancer Therapy Cureus article:  A Comprehensive Review of Monoclonal Antibodies in Modern Medicine: Tracing the Evolution of a Revolutionary Therapeutic Approach Association of Cancer Care Centers (ACCC) homepage Cancer Immunology, Immunotherapy article: Therapeutic Antibodies in Oncology: An Immunopharmacological Overview Drugs@FDA package inserts Future Oncology article: Biosimilars: What the Oncologist Should Know Hematology/Oncology Pharmacy Association homepage National Comprehensive Cancer Network homepage Network for Collaborative Oncology Development and Advancement (NCODA) subcutaneous therapy article Oncolink: Side Effects of Immunotherapy World Health Organization: New International Nonproprietary Names (INN) Monoclonal Antibody Nomenclature Scheme To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Prior to monoclonal antibodies, all we really had were these toxic chemotherapies or toxic radiation, so it was recognized how great it would be if we could have a treatment that was much more specific to the tumor cells and have agents that have less toxicities. These advancements in monoclonal antibody production began in the 1980s. ... Eventually, we had the first monoclonal antibody that was approved by the U.S. Food and Drug Administration (FDA) for an oncologic indication, rituximab." TS 4:14  "Nowadays, we do have treatments that are also considered tumor-agnostic. This is when a patient has a certain biomarker, then that treatment can be given and FDA approval was given, regardless what type of tumor the patient has. We typically see these kinds of tumor-agnostic therapies more so in patients who have recurrent or advanced diseases in solid tumors. One monoclonal antibody example that comes to mind is dostarlimab. That's a checkpoint inhibitor that's approved for patients who are deficient in mismatch repair mechanism." TS 23:48 "Our immune system constantly has this surveillance system and it's able to recognize foreign pathogens, abnormal cells, and even precancerous cells. And they're able to eliminate them before they become cancerous. But on the flip side, one of the regulatory mechanisms that we have so our immune system doesn't attack itself is the presence of checkpoints. When these checkpoints bind to their ligands, this can then act as an off switch so that, again, our immune system is not going to attack itself. But then the tumor cells can take advantage of this and actually use this mechanism to evade the immune system. So, when we're giving a checkpoint inhibitor, now we're removing that off switch. As a consequence, common adverse effects can include things like immune mediated adverse events. These most commonly affect the skin, gastrointestinal tract, and liver. Essentially, this can cause any '-itis' you can think of." TS 26:36 "Looking at strategies to prevent infusion reactions, one example is the use of premedication. If premedication is recommended, this typically includes any combination of antipyretics, which is typically acetaminophen. Antihistamine, which is typically an H1 antagonist like diphenhydramine. Although, there could be cases where we want to substitute this agent because maybe the patient has been tolerating therapy okay, and they're having a lot of side effects. So, we might use a second-generation antihistamine in some cases. The premedication may be given with or without some kind of steroid, whether that's methylprednisolone, hydrocortisone, or dexamethasone." TS 29:53 "We tend to think of monoclonal antibody usage to be primary oncology, but that's not really the case. The first monoclonal antibodies that were developed were not for oncologic indications, they were for transplant indication for cardiac indication. So, they're really diversely utilized across all specialties and medicines. We have monoclonal antibodies for hyperlipidemia, for neurology, for rheumatology, so the uses are so very expansive across all specialties." TS 41:01

Send us a textIn this Power Surge follow-up episode, Dr. Mel reminds building leaders that leadership growth doesn't require a new role, a new year, or perfect timing. Inspired by A Christmas Carol, this short reflection challenges principals and school leaders to remember that even late in the school year, small, intentional leadership shifts can change culture and impact.Reflection Question:

Hawaiian Airlines put out an alert on its website notifying guests to arrive at airports early because of an issue with TSA pre-check that's slowing down lines. Honolulu's prosecutor has secured an indictment for Micah Auna, 29, the man accused of killing his mother in Hawaii Kai last week. And fans are still buzzing after Christmas Eve's thrilling Hawaii Bowl showdown between the Rainbow warriors and the Cal Golden Bears. See omnystudio.com/listener for privacy information.

Changes for visitor access in Lahaina. What boat tour companies will now have to do to operate. We hear from fire officials on how to handle rechargeable lithium-ion batteries, including those in your smartphone, to keep your family safe. Census data shows that more Native Hawaiians now live outside Hawaii than on the islands.See omnystudio.com/listener for privacy information.

In this episode, I have the profound honor of sitting down with Thomas Drake, a former senior executive at the National Security Agency (NSA) who became one of the most consequential whistleblowers of our time. After exposing post-9/11 mass surveillance and systemic abuses of power, Thomas faced 35 years in prison under the Espionage Act, only to walk free as a living testament to integrity under fire.We journey through his "moment of truth" at the NSA and dive deep into his evolution from a veteran of the Air Force, Navy, and CIA to a seeker of spiritual and metaphysical truth. Together, we explore the fine line between secrecy and transparency, the dangers of a "highly ordered dystopia," and how we can collapse the potentiality of a dark future to manifest a redeemed world.This conversation is a bridge between the "shadow lands" of national security and the blazing hope of a human rebirth, reminding us that we are not just human doings, but human interbeings.In this episode, we explore:04:34 How a near-death experience at age four sparked a lifelong search for truth.11:50 Reporting to the NSA on 9/1111:00 The "Shadow Lands" of secrecy: How government institutions become addicted to hiding the truth.27:30 The cost of courage: Facing 10 felony counts and 35 years in prison for upholding the Constitution.30:13 How intentionality collapses the future into our present reality.36:42 Corporate Futurism vs. Conscious Futurism: Breaking the "spell" of inevitable technocracy.38:20 Using ancient memory to navigate the complexity of the modern nexus point.42:15 Why human governments fail and how we must learn to govern ourselves.50:13 Moving past the pathology of power to find unity on our "privileged planet." 51:55 The vision of a redeemed Earth and the upcoming transition beyond the event horizon.About Thomas DrakeThomas Drake is a former senior executive at the National Security Agency turned whistleblower on post-9/11 mass surveillance, government malfeasance, and intelligence failures. A veteran of the Air Force, Navy, and CIA, he was the defendant in a signature Espionage Act case during the Obama administration where he faced 35 years in prison for telling the truth. He holds a PhD in Public Policy and Administration, focusing on the consequences of secrecy. Today, Thomas is a dedicated defender of civil liberties and a "conscious futurist" peering past the abyss to glimpse a redeemed world. He has been featured in the documentary "Silenced," PBS Frontline's "United States of Secrets," and 60 Minutes.

Send us a textIn this holiday episode of The Empowered Educator Show, Dr. Mel reflects on leadership lessons from A Christmas Carol and connects them to the real work of building leaders. This episode focuses on reflection, relationships, school culture, leadership legacy, and the power of transformation.What I Cover:Why relationships matter more than authorityHow leadership experiences shape decision-makingWhat school culture reveals about leadership impactWhy legacy matters more than titleHow leaders can change course at any point in the yearBest For: Principals, assistant principals, instructional coaches, superintendents, and aspiring school leaders.Resource Mentioned:Dickens, C. (1843). A Christmas Carol. Chapman & Hall.Download Upside and use my code MELINDA35278 to get 15¢ per gallon extra cash back on your first gas fill-up and 10% extra cash on your first food purchase! Download Fetch app using this link, submit a receipt and we'll both score bonus points. Calling All Educators! I started a community with resources, courses, articles, networking, and more. I am looking for members to help me build it with the most valuable resources. I would really appreciate your input as a teacher, leader, administrator, or consultant. Join here: Empowered Educator Community Book: Educator to Entrepreneur: IGNITE Your Path to Freelance SuccessGrab a complimentary POWER SessionWith Rubi.ai, you'll experience cutting-edge technology, research-driven insights, and efficient content delivery.email: melinda@empowere...

The Bows take on the Cal Golden Bears in the Hawaii Bowl. Friends of Amber Jackson have renewed hope that her killer will be caught after a major breakthrough in the 15-year-old cold case. Washington authorities locate the second vehicle that hit and killed a state trooper from Hawaii. See omnystudio.com/listener for privacy information.

Two crashes, one fatal, are reported across the state. University of Hawaii's Rainbow Warriors win the Hawaii Bowl for the first time in six years. A new shelter aims to help Hawaiian Home Lands beneficiaries living on the streets.See omnystudio.com/listener for privacy information.

Send us a textOn Christmas Eve, the noise fades and the pace slows—inviting leaders to pause in a way they rarely allow themselves to do. In this special Power Surge episode, Mel speaks directly to school leaders who have been carrying responsibility, expectations, and unseen weight all year long. This episode is a reminder that leadership doesn't always look like doing more. Sometimes, the most faithful leadership choice is stillness, trust, and rest.Grounded in the Christmas story and Scripture, this episode encourages leaders to release pressure, reflect with gratitude, and remember that God often works most powerfully in quiet moments.Scripture Referenced:Matthew 1:21 — Hope entering the world quietlyPsalm 46:10 — The power of stillness and trustDownload Upside and use my code MELINDA35278 to get 15¢ per gallon extra cash back on your first gas fill-up and 10% extra cash on your first food purchase! Download Fetch app using this link, submit a receipt and we'll both score bonus points. Calling All Educators! I started a community with resources, courses, articles, networking, and more. I am looking for members to help me build it with the most valuable resources. I would really appreciate your input as a teacher, leader, administrator, or consultant. Join here: Empowered Educator Community Book: Educator to Entrepreneur: IGNITE Your Path to Freelance SuccessGrab a complimentary POWER SessionWith Rubi.ai, you'll experience cutting-edge technology, research-driven insights, and efficient content delivery.email: melinda@empowere...

The suspect accused of murdering his mother in Hawaii Kai appears in court and claims he acted on self defense. The wife of a man who assaulted the Moanalua's assistant athletic director is now under arrest. Pending court approval, Kamehameha Schools will no longer require tuition beginning with the 2026-27 school year. See omnystudio.com/listener for privacy information.

Economist Carl Bonham from the University of Hawaii Economic Research Organization discusses what's in store for the state's economy in 2026, including the impact from Hawaii's minimum wage increase. And from the New Year's deadly fireworks accident to ICE raid arrests, HNN's Daryl Huff helps break down some of the top news stories from 2025.See omnystudio.com/listener for privacy information.

A major break in a 15-year-old cold case on Kauai has police searching for the man they say killed Amber Jackson. The man accused of murdering his mother at her Hawaii Kai home appears in court as we learn new details about what police found at the crime scene. And the U.S. Justice Department defends President Donald Trump after releasing more documents related to Epstein. See omnystudio.com/listener for privacy information.

The search for a murder suspect continues 15 years after the death of Amber Jackson. Honolulu crews stopped a sewer leak that discharged effluent near Honolulu Harbor for 17 hours. One year after the current Kilauea eruption began, episode 39 continues, with lava fountains reaching heights of over 1,000 feet.See omnystudio.com/listener for privacy information.

A seismic shift for Kamehameha Schools. The move officials are making in the face of a lawsuit over admissions policies. State officials are warning that some seasonal scams are targeting residents. In October, over a thousand people in the Native Hawaiian Community attended the Hawaiian Convention. How do they maintain their identity while on the continent? See omnystudio.com/listener for privacy information.

We're closing out the year with a special episode with EFG Holding, and I'm joined today by the Group's Chief Finance & Operations Officer, Mohamed Abdel Khabir. Mohamed joined the investment bank in 2008 and took on the CFO role in 2016. Earlier this year, he took on the additional responsibility of Operations, which includes Marketing, Technology & Administration. Mohamed has been actively involved in EFG Holding's transformation from a MENA-based investment bank to its current avatar—a leading financial institution with a universal bank in Egypt and a leading investment bank in MENA. We'll be back in the New Year with a bit of a refresh, new episodes with some amazing guests from across the region. In the meantime, you can catch up on episodes you might have missed here: Chapters 0:00 Coming up... 2:54 EFG Holding's transformation 3:53 Regional strategy and global footprint 10:00 Lessons learnt from acquisitions 17:34 Leadership and fostering talent 23:04 Investor relations 25:51 ‘Resilience is not a choice' 29:21 The Lightning Round Learn more about your ad choices. Visit megaphone.fm/adchoices

A 29-year-old man is charged with killing his mother in Hawaii Kai. Hawaii Bowl week has arrived; the Bows and the Golden Bears meet the media as former teammates reunite for a Christmas Eve showdown. And a women allegedly driving under the influence crashed into a man, woman, and child last night on Kauai. See omnystudio.com/listener for privacy information.

The city is working to stop sewage from spilling into a stream near Honolulu Harbor after an equipment failure near Pier 16. Hawaii leaders sound the alarm as the Trump administration proposes more extensive background checks on visitors. And more bus routes are planned to help fans get to the Hawaii Bowl to watch the University of Hawaii face Cal.See omnystudio.com/listener for privacy information.

We're learning more about the potential direction of the state in upcoming fiscal year. What the Governor's proposed budget is revealing about his priorities. A payout for a man wrongfully imprisoned for years. Christmas is just 2 days away. If you still need to start your holiday shopping we'll give you some last-minute ideas.See omnystudio.com/listener for privacy information.

The suspect accused of murdering his mother in Hawaii Kai appears in court. Hawaii leaders voice tourism concerns over the Trump administration's plan to increase vetting of visitors to the country. Maui County is starting a new method for projecting water demand.See omnystudio.com/listener for privacy information.

Trump is covering up torture again. Based on a newly leaked internal 60 Minutes memo, the Trump Administration used its power over CBS' parent company to “spike” and “veto” an investigative report that was to air this past weekend about the torture prison of El Salvador virtually run by the Administration, and 60 Minutes journalists are resigning in protest. Michael Popok reports on Trump's continued assault on corporate media to bury the uncomfortable truths of his policies. Indacloud: If you're 21 or older, get 25% OFF your first order + free shipping @IndaCloud with code LEGALAF at https://inda.shop/LEGALAF! #indacloudpod Subscribe:  @LegalAFMTN  Visit https://meidasplus.com for more! Remember to subscribe to ALL the MeidasTouch Network Podcasts: MeidasTouch: ⁠https://www.meidastouch.com/tag/meidastouch-podcast⁠ Legal AF: ⁠https://www.meidastouch.com/tag/legal-af⁠ MissTrial: ⁠https://meidasnews.com/tag/miss-trial⁠ The PoliticsGirl Podcast: ⁠https://www.meidastouch.com/tag/the-politicsgirl-podcast⁠ Cult Conversations: The Influence Continuum with Dr. Steve Hassan: ⁠https://www.meidastouch.com/tag/the-influence-continuum-with-dr-steven-hassan⁠ Mea Culpa with Michael Cohen: ⁠https://www.meidastouch.com/tag/mea-culpa-with-michael-cohen⁠ The Weekend Show: ⁠https://www.meidastouch.com/tag/the-weekend-show⁠ Burn the Boats: ⁠https://www.meidastouch.com/tag/burn-the-boats⁠ Majority 54: ⁠https://www.meidastouch.com/tag/majority-54⁠ Political Beatdown: ⁠https://www.meidastouch.com/tag/political-beatdown⁠ On Democracy with FP Wellman: ⁠https://www.meidastouch.com/tag/on-democracy-with-fpwellman⁠ Uncovered: ⁠https://www.meidastouch.com/tag/maga-uncovered⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Kriss is back with another episode of the Insanity Check to cover this week's dose of insanity in the world. This week he's joined by Ro and well...everything is just really really stupid Topics for the show: Everyone is talking about the Epstein List and it's not even in the top 25 dumb/bad things the Administration is doing The best way to bring down inflation is to just make up the numbers on the inflation report Yahoo Finance names OpenAI 'Company of the Year' because racking up ton of debt and costs with no actual plan to pay it off is what pass as good business these days Disney signs deal to license to OpenAI (more costs for OpenAI) while giving a pinky promise to buy OpenAI equity Waymo didn't make sure their vehicles could work if the power for traffic lights went out; How does something like this happen (and Waymo is supposed to be the 'good' autonomous vehicle company) Just because CEOs 'run' companies that make a lot of money doesn't make them smart Roblox is getting sued by Tennessee (and other states) for making an unsafe environment for kids. Good thing their CEO didn't go on a podcast with two journalist and say really stupid and damaging things..oh wait The full interview (you need to watch it) is here Guest: Ro @bookblerd.bsky.social‬   Like what you hear? Subscribe so you don't miss an episode!   Follow us on BlueSky: @InsanityReport  

Increased enforcement and harsher penalties -- That's the promise from local law enforcement as they look to crack down on illegal fireworks this holiday season. A move by Congress not to extend subsidies for Obamacare policies will most likely affect many Hawaii residents. And tomorrow marks one year since the current Kilauea eruption began.See omnystudio.com/listener for privacy information.

An update in the killing of a woman in Hawaii Kai, police announce a man believed to be her son has been charged. A special ceremony to mark the swearing in of the first ocean safety chief. Multiple people displaced after overnight fire in Honolulu.See omnystudio.com/listener for privacy information.

On today's podcast:1) The US’s pursuit of a third oil tanker off the coast of Venezuela has intensified a blockade that the Trump administration hopes will cut off a vital economic lifeline for the country and isolate the government of President Nicolás Maduro. The US Coast Guard chased the US-sanctioned Bella 1 on Sunday as it was en route to Venezuela. It boarded Centuries, a ship owned by a Hong Kong-based entity, on Saturday — the first non-sanctioned vessel to be targeted. Another very large crude carrier, the Skipper, was intercepted on Dec. 10. The moves on three separate vessels represent the most concerted attempt to date to sever the financial links sustaining a government that Washington says is led by a drug-trafficking cartel, and one that it has also recently designated as a foreign terrorist organization. Maduro has so far withstood the onslaught, but the blockade is beginning to limit hard currency and to hurt an already battered economy.2) Democratic lawmakers said they plan to explore “all legal options” after the Justice Department announced it will not release all documents about the disgraced financier Jeffrey Epstein by the Friday deadline, threatening to prolong a high-stakes political fight as the midterm elections come into view. The US Justice Department released thousands of pages of pictures, phone records and notes from investigations into notorious sex offender on Friday, revealing new details about the late financier’s relationships with prominent business leaders and politicians. The department said more files will be released in coming weeks because the volume of material was too much to process by the Friday deadline set by Congress, sparking rebukes from many Democrats. The tranche included heavy redactions, a step intended to comply with the provisions of the law including protections for survivors and other accommodations.3) A Supreme Court ruling that scraps President Trump’s tariffs — and refunds the import fees collected — would create a major “administrative problem,” the president’s top economic adviser said Sunday. “We really expect the Supreme Court is going to find with us,” Kevin Hassett, director of the National Economic Council, told CBS’s Face the Nation. Even if the court didn’t find in the Trump administration’s favor, Hassett argued it would be “pretty unlikely that they’re going to call for widespread refunds because it would be an administrative problem to get those refunds out there.” The Supreme Court is weighing a legal challenge to tariffs Trump imposed on dozens of nations under the 1977 International Emergency Economic Powers Act. Administration officials have drawn up options for reimposing import taxes in case of an adverse ruling, while publicly maintaining that a court defeat is unlikely.See omnystudio.com/listener for privacy information.

Die Epstein-Akten sollten Transparenz bringen - stattdessen wächst der Streit im Trump-Lager.In dieser Folge spricht Paul mit Gudrun Engel, Studioleiterin der ARD in Washington, über die erste Tranche der veröffentlichten Datensätze: Warum kamen zunächst nur rund 13.000 Dokumente - obwohl deutlich mehr erwartet wurden? Was wurde geschwärzt, nach welchen Kriterien und warum wurden Opfervertreter teils erst Stunden vorher informiert? Und was bedeutet es politisch, dass Trumps Name bislang nur am Rand auftaucht, während der Blick der Administration auffällig stark auf Bill Clinton gelenkt wird?Außerdem geht es um die Nervosität in der MAGA-Bewegung: Wie sehr trifft die Epstein-Debatte den Markenkern der Basis - Kampf gegen eine „korrupte Elite“ - und wie beschädigt der Zickzackkurs von Trump und Justizministerin Pam Bondi die Glaubwürdigkeit der Regierung?Im zweiten Teil: Machtkampf bei Turning Point USA. Warum unterstützt Erika Kirk ausgerechnet jetzt J.D. Vance - und was sagt das über die Zeit nach Trump? Gudrun Engel ordnet ein, wie sich die Lager zwischen klassisch-konservativen Stimmen wie Ben Shapiro und radikaleren Influencern wie Tucker Carlson, Candace Owens oder Steve Bannon weiter verhärten - und warum diese Auseinandersetzung für die Republikaner Richtung 2028 wichtiger werden könnte, als viele in Europa denken.Wenn euch der Podcast gefällt, dann lasst gerne Like & Abo da! Ihr habt Fragen, Kritik oder Themenvorschläge? Schreibt an ronzheimer@axelspringer.comPaul auf Instagram | Paul auf XUnd ganz neu: Paul jetzt auch auf YouTube!Redaktion: Filipp Piatov & Lieven JenrichExecutive Producer: Daniel van Moll Hosted on Acast. See acast.com/privacy for more information.

Julie A. Parsons, MDHaberfield Endowed Chair in Pediatric Neuromuscular DisordersProfessor of Clinical Pediatrics and NeurologyUniversity of Colorado School of Medicine, Children's Hospital ColoradoAurora, CO, USAThe gene transfer trials for musculoskeletal disorders, if we look at musculoskeletal and neurologic disorders, we really do have the highest success rate in terms of treatment, but we also carry the highest incidence of treatment-emergent severe adverse events. And why is that true? Yesterday, when we were hearing about Donovan as well, we looked and said, When the first gene transfer therapies were started, he had a single muscle that was injected.When we look at Luxturna, we injected the retina. Now, what is happening with these disorders is that we're giving these huge, massive doses of viral vector to patients. There haven't been a lot of gene transfer therapies that have reached the market. But you saw yesterday, so many gene transfer therapies being worked on, but there are very few that have actually come to market. There are a couple of reasons for that.One is with the indications that we have, we know that the musculoskeletal disorders are most likely to achieve benefit, but there are the high risk of severe adverse events. Route of Administration, IV, for most of our disorders is the way we're going. We may end up having some Intrathecal therapies as well that are coming on board, but right now it's IV, and that means, a huge dose of this viral vector and antigenic risk that is being administered.In the vector design now, we actually have more specific vectors as well as promoters that are being utilized to really target specific tissues, so that we're able to focus in a little bit more on the tissues that we want to have affected. And then the dose has gone from these little tiny local injections to really systemic, much broader. And now our patients, are larger. So we're giving a viral genome per kilo dose that is just massive as we look at that.Then there really are challenges in terms of the translation of clinical trials to commercial treatment with these agents. And we don't always know, we're not always great when we do tests in clinical trials in small populations, about when that's broadened to the commercial availability and we hit larger heterogeneous populations.There are safety issues arising from these therapies, and I think that we have some experience now, certainly with the three diseases that I mentioned at the beginning, in terms of collecting some data and information to have a little bit more of an idea what to expect. Although to me, the recurring esteem is always, expect the unexpected. Because we still are learning about this. Hepatotoxicity. We know that transaminitis is something that we see in almost every gene transfer therapy that has been delivered, and we have to watch really, really closely and follow our patients closely for this. We also have to select patients that we don't think have risk for additional liver injury or underlying liver pathology, because as we found out in the XLMTM boys, we missed that. Thrombotic Microangiopathy. We look at this disorder. We've had deaths in SMA from TMA. We have Duchenne patients that have had TMA.This is scary because as many of us as clinicians who have treated patients, you know that we end up getting thrombocytopenia. So is that it this time, or are they going to be fine, or the platelet is going to go back to normal? This is another one that we have to watch really, really closely for. Cardiac Toxicity. We have had cardio myositis. We've had deaths from cardiac toxicity.Something really, really important for us to think about. In little kids, vomiting could be a sign of cardiac myositis. And for most of us who've treated patients with gene transfer therapy, what's one of the first issues that you get?You get nausea of vomiting, they don't feel good. So is that myocarditis or is it just a standard side effect that we're seeing with treatment? Importantly, as we discovered, there actually can be an immune response to the transgene. It's not just the viral vector capsid, it's actually the transgene as well. That was discovered in patients who were treated for Duchenne. So that's a really important thing in terms of looking now at what's our patient's selection and how do we pick the right patients.Next part, Dr. Parsons will discuss understanding and preparing risk factors associated with AAV gene therapies.

The VMUG home lab portal has been live for 2 weeks now, we are tracking 5 bugs. We now have resolution for the download "come back later bug" as well as will be publishing support for the Administration and A/rchitect 2024 certification (previous release of vcp). We are responding to advantage@vmug.com escalations and getting things fixed now that tokens are live.

Trump's relentless assault on the DOJ's credibility has lead to Grand Juries, Juries, Judges and law students all rejecting the DOJ leading to pile up of losses. Trump's criminal defense team masquerading as the DOJ leadership are also moving closer to possible criminal prosecution and indictment related to the continued obstruction around the Epstein Files coverup and the coverup of the coverup. Federal Judges are ramping up the pace of their blistering orders against the Trump DOJ at a record pace. Public support for lawsuits against the Trump Administration is contributing mightily to Trump's loss record. As the lower courts are “holding the line” against Trump's lawlessness, the need for Supreme Court reform in the next Administration is laid bare for all the Voters to see. And the Legal AF Youtube channel likely gets its ONE MILLIONTH SUBSCRIBER this weekend! All this and so much more as Ben and Popok take the controls tonight of the top rated Legal AF podcast. Support Our Sponsors: Corn Bread Hemp: Head to https://cornbreadhemp.com/LEGALAF and use code LEGALAF to get holiday BOGO savings. Miracle Made: Upgrade your sleep with Miracle Made! Go to https://TryMiracle.com/LEGALAF and use the code LEGLAF to claim your FREE 3 PIECE TOWEL SET and SAVE over 40% OFF. Aura Frames: Visit https://AuraFrames.com and get $45 OFF their BEST-SELLING Carver Mat frames with promo code: LEGALAF Udacity: For 40% off your order, head to https://Udacity.com/LEGALAF and use code LEGALAF Learn more about the Popok Firm: https://thepopokfirm.com Subscribe to Legal AF Substack: https://substack.com/@legalaf Check out the Popok Firm: https://thepopokfirm.com Remember to subscribe to ALL the MeidasTouch Network Podcasts: MeidasTouch: https://www.meidastouch.com/tag/meidastouch-podcast Legal AF: https://www.meidastouch.com/tag/legal-af MissTrial: https://meidasnews.com/tag/miss-trial The PoliticsGirl Podcast: https://www.meidastouch.com/tag/the-politicsgirl-podcast Cult Conversations: The Influence Continuum with Dr. Steve Hassan: https://www.meidastouch.com/tag/the-influence-continuum-with-dr-steven-hassan Mea Culpa with Michael Cohen: https://www.meidastouch.com/tag/mea-culpa-with-michael-cohen The Weekend Show: https://www.meidastouch.com/tag/the-weekend-show Burn the Boats: https://www.meidastouch.com/tag/burn-the-boats Majority 54: https://www.meidastouch.com/tag/majority-54 Political Beatdown: https://www.meidastouch.com/tag/political-beatdown On Democracy with FP Wellman: https://www.meidastouch.com/tag/on-democracy-with-fpwellman Uncovered: https://www.meidastouch.com/tag/maga-uncovered Learn more about your ad choices. Visit megaphone.fm/adchoices

The Constitution Study with Host Paul Engel – Presidential power continues to expand under both parties, with executive mandates increasingly replacing constitutional governance. From artificial intelligence policy to immigration and surveillance, illegal orders persist despite public expectations of reform. The problem endures not in the White House alone, but in representatives who fail to recognize or challenge unlawful authority...

Two people are now under arrest after a welfare check in Hawaii Kai led to the discovery of a body. After a wet week for the islands, will downpours continue into the holidays? If getting fit is one of your New Year's goals, UFC Gym offers these tips to get you started.See omnystudio.com/listener for privacy information.

The Constitution Study with Host Paul Engel – Presidential power continues to expand under both parties, with executive mandates increasingly replacing constitutional governance. From artificial intelligence policy to immigration and surveillance, illegal orders persist despite public expectations of reform. The problem endures not in the White House alone, but in representatives who fail to recognize or challenge unlawful authority...

As President Trump continues his nationwide tour to tout his economic policies, some in his party are concerned that voters won't feel the effects of an improving economy in time for next year's midterm elections, especially with the soon to expire Obamacare subsidies on track to raise insurance premiums for millions of Americans. FOX News Senior White House Correspondent Jacqui Heinrich joins the Rundown to explain what the economic outlook is like on Capitol Hill, and where the big picture numbers differ from everyday reality. Later, FDA Commissioner Dr. Marty Makary joins to give an inside look on what the Administration is doing to lower healthcare costs for Americans. Learn more about your ad choices. Visit podcastchoices.com/adchoices

It's a First Alert Weather Day for parts of the state. We're tracking the impacts of a system that storm led to flooding, and even a tornado warning for Niihau this morning. Continued fallout in the attack of a Moanalua high athletics official as one of Hawaii's most storied athletes weighs in. And the U.S. Justice department released thousands of documents related to Jeffrey Epstein, but lawmakers are worried the rest of the files will not be released by the lawful deadline. See omnystudio.com/listener for privacy information.

With New Year's approaching, law enforcement is warning the public about stricter penalties for illegal fireworks. Honolulu police say a man caught on camera is wanted in connection with a break-in at a local school. A major nurses' union has filed a complaint against Kaiser Permanente, saying hospital leaders stopped contract talks and tried to work around the agreed-upon bargaining process.See omnystudio.com/listener for privacy information.

As President Trump continues his nationwide tour to tout his economic policies, some in his party are concerned that voters won't feel the effects of an improving economy in time for next year's midterm elections, especially with the soon to expire Obamacare subsidies on track to raise insurance premiums for millions of Americans. FOX News Senior White House Correspondent Jacqui Heinrich joins the Rundown to explain what the economic outlook is like on Capitol Hill, and where the big picture numbers differ from everyday reality. Later, FDA Commissioner Dr. Marty Makary joins to give an inside look on what the Administration is doing to lower healthcare costs for Americans. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The New Yorker staff writer Isaac Chotiner joins Tyler Foggatt to reflect on several of the most notable interviews he conducted in 2025. They discuss competing theories about the origins of political violence over the past year, how to understand President Trump's approach to power in his second term, and the challenges of covering an Administration that rarely appears to be driven by a coherent ideological framework. They also revisit two high-profile interviews: one with the former White House press secretary Karine Jean-Pierre, about her decision to leave the Democratic Party, and another with the legal scholar Cass Sunstein, on the limits of “big tent” politics and his curious friendship with Henry Kissinger. This week's reading: “In the Wake of Australia's Hanukkah Beach Massacre,” by Isaac Chotiner “The Federal Judge at the Trump Rally,” by Ruth Marcus “The Year in Trump Cashing In,” by John Cassidy “The Party Politics of Sovereign House,” by Emma Green “Want to Talk to Zohran Mamdani? Get in Line,” by Eric Lach The Political Scene draws on the reporting and analysis found in The New Yorker for lively conversations about the big questions in American politics. Join the magazine's writers and editors as they put into context the latest news—about elections, the economy, the White House, the Supreme Court, and much more. New episodes are available three times a week. Tune in to The Political Scene wherever you get your podcasts.  Learn about your ad choices: dovetail.prx.org/ad-choices

Issues Emergency Message To Trump, Lays Out Battle Plan That If Trump Executes Will SAVE America & His Administration! Plus, RFK Jr. Nukes The Trans Cult From Orbit, Announces Sweeping Federal Ban On Sterilization Drugs & Surgeries

The Administration's new National Security Strategy document contains exaggerations, contradictions, insults, racism, posturing and slamming, which is to say nothing of the important topics it does not address. Amb. Charlie Ray takes the ideological manifesto apart for us, with discussion of the existential consequences for America and for our species.

A federal judge is not pleased with Trump's ballroom but may have to wait longer to do something about it. A federal judge is not pleased with the DOJ, and does something about it. Trump's Chief of Staff isn't pleased with a lot of people in the Administration, and does something about it. Trump pulls the plug on fighting over his phony US Attorneys. Another bad news cycle, another phony defamation case filing for Trump. All at the Intersection with host Michael Popok only on the Meidas Touch Network. Sundays for Dogs: Get 40% off your first order of Sundays. Go to https://sundaysfordogs.com/legalaf or use code LEGALAF at checkout. Aura Frames: Exclusive $35 off Carver Mat at https://on.auraframes.com/legalaf Promo Code LEGALAF Check out The Popok Firm at: https://thepopokfirm.com Subscribe: https://www.youtube.com/@LegalAFMTN?sub_confirmation=1 Legal AF Substack: https://substack.com/@legalaf Follow Legal AF on Bluesky: https://bsky.app/profile/legalafmtn.bsky.social Follow Michael Popok on Bluesky: https://bsky.app/profile/mspopok.bsky.social Subscribe to the Legal AF by MeidasTouch podcast here: https://podcasts.apple.com/us/podcast/legal-af-by-meidastouch/id1580828595 Remember to subscribe to ALL the MeidasTouch Network Podcasts: MeidasTouch: https://www.meidastouch.com/tag/meidastouch-podcast Legal AF: https://www.meidastouch.com/tag/legal-af MissTrial: https://meidasnews.com/tag/miss-trial The PoliticsGirl Podcast: https://www.meidastouch.com/tag/the-politicsgirl-podcast The Influence Continuum: https://www.meidastouch.com/tag/the-influence-continuum-with-dr-steven-hassan Mea Culpa with Michael Cohen: https://www.meidastouch.com/tag/mea-culpa-with-michael-cohen The Weekend Show: https://www.meidastouch.com/tag/the-weekend-show Burn the Boats: https://www.meidastouch.com/tag/burn-the-boats Majority 54: https://www.meidastouch.com/tag/majority-54 Political Beatdown: https://www.meidastouch.com/tag/political-beatdown On Democracy with FP Wellman: https://www.meidastouch.com/tag/on-democracy-with-fpwellman Uncovered: https://www.meidastouch.com/tag/maga-uncovered Coalition of the Sane: https://meidasnews.com/tag/coalition-of-the-sane Learn more about your ad choices. Visit megaphone.fm/adchoices

The Trump Administration has put billions of dollars into building an immigration superstructure meant to punish those who have done nothing wrong and intimidate everyone else – including legal immigrants and US citizens. Weirdly enough, that's proving not to be very popular. According to new polling from the Associated Press, Trump is now deeply underwater on the subject of immigration – with 60 percent of respondents opposing his handling of the issue. So to talk more about what's happening with immigration, from the Administration's plans for 2026 to its many horrifying offenses, we spoke to Aaron Reichlin-Melnick. He's a Senior Fellow at the American Immigration Council.And in headlines, dueling healthcare bills fail in the Senate, nature-lovers push back on plans to make President Trump the face of their National Park adventures, and Disney becomes the first major studio to license its characters to OpenAI's video generator.This holiday season, gift someone a Friends of the Pod subscription or treat yourself. Learn more at crooked.com/friends. Subscribing is the best way to support independent progressive media.Show Notes: Call Congress – 202-224-3121Subscribe to the What A Day Newsletter – https://tinyurl.com/3kk4nyz8What A Day – YouTube – https://www.youtube.com/@whatadaypodcastFollow us on Instagram – https://www.instagram.com/crookedmedia/For a transcript of this episode, please visit crooked.com/whataday Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.