Dr RR Baliga's Internal Medicine MUST KNOW FACTS Podcasts for Physicians and Physician Extenders. Not medical advice. www.MasterMedFacts.com

The new Lancet Series on ultra-processed foods offers a striking insight: as UPFs rise globally, traditional whole-food diets decline—bringing nutrient imbalance, overeating, toxic exposures, and hyper-palatable formulations that quietly reshape health trajectories.

Home-delivered DASH-patterned groceries paired with dietitian counseling meaningfully lowered blood pressure and LDL cholesterol among Black adults living in food deserts

☕ DECAF Trial insight! A new JAMA study shows that daily caffeinated coffee may lower recurrence of atrial fibrillation compared with abstinence. Patients drinking ~1 cup/day had 47% recurrence vs 64% with abstinence (HR 0.61, p=0.01)





SOFA-2 is here — a major advance in assessing organ dysfunction in critical illness

Rethinking "default lines" in the ICU

The immune clock starts earlier than we think ⏳


A new era for complex mitral regurgitation. The ENCIRCLE pivotal trial in The Lancet reports that fully percutaneous, transfemoral, transseptal TMVR (SAPIEN M3) achieved durable MR reduction (≈96% ≤1+ at 1 year), low early mortality, and meaningful improvement in symptoms and quality of life for patients unsuitable for surgery or TEER. A third pathway for mitral disease is emerging—one built on precision access, valve-in-valve durability planning, and advancing patient selection. Innovation meeting clinical need.





Hair Loss in Women” (The New England Journal of Medicine 2025; DOI 10.1056/NEJMcp2412146)

