Podcasts about gazella

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Best podcasts about gazella

Latest podcast episodes about gazella

Bandeja de entrada de Radio 3
Bandeja de entrada - Tamino, Gitano de Palo...- 25/03/25

Bandeja de entrada de Radio 3

Play Episode Listen Later Mar 25, 2025 58:40


...y más nuevas canciones de Gazella, Σtella, Nadah El Shazly, Patrick Wolf, Peter Murphy, Miki Berenyi Trio y The Horrors.Escuchar audio

DIÁRIO DE BORDO
#1337 - Uma Gazella no pé e o tamanho party size

DIÁRIO DE BORDO

Play Episode Listen Later Mar 11, 2025 25:02


Siga a gente emhttp://youtube.com/@diariodebordopod

Bandeja de entrada de Radio 3
Bandeja de entrada - María Yfeu, Fontaines D.C., Gazella... - 21/02/25

Bandeja de entrada de Radio 3

Play Episode Listen Later Feb 21, 2025 58:45


...y más nuevas canciones de La Plata, Tatuaje, Alcalá Norte, Lorena Álvarez, Zahara, Puma Blue, Richard Dawson y Basia Bulat.Escuchar audio

Independents
Independents - 20/02/2025

Independents

Play Episode Listen Later Feb 20, 2025 59:59


Toxicosmos
La Luz y sus dosis de pop alucinógeno.

Toxicosmos

Play Episode Listen Later May 27, 2024 120:18


La Luz llegan desde California con un segundo disco cargado de canciones lisérgicas de cuidadas melodías pop y el toque justo de psicodelia. Firman nuestro disco de la semana y protagonizan la portada de nuestra revista sonora. En nuestro repaso a la actualidad internacional suenan también Maximo Park, Travis, Somersby, BD Gottfried, Pom Poko, Paul Allen, The Kantors, Katy J. Pearson, Lauren Minear, Landon Hoffman, Casey Frazier, Philine y Sophia Sheth, todos con material nuevo. Los protagonistas de la actualidad nacional son Carolina Durante, Los Punsetes, Corte!, Salvar Doñana, Amigas!, Julia Amor, Axolotes Mexicanos, Noise Box, Verona, Kokoshca, Oques Grasses, Novio Caballo, Serch, Perdón, Ciutat y Los Estanques. El punto bailable lo ponen Amateur remezclados por Nacho Canut y la versión de la semana la firman Gazella con un clásico de Las Grecas. Y como recomendación te hablamos del festival Primavera Sound que se celebra esta semana en Barcelona.

Les Golfes de Gelida
Les Golfes · 103

Les Golfes de Gelida

Play Episode Listen Later Mar 8, 2024 51:26


Ei! Si tu!, estimat oient. No sabem que fas llegint aquest paragrafàs , quan podríeu estar escoltant el programa d'aquesta setmana. A més, és un programa que té de tot! Molt bones descobertes, varietat a dojo i fins i tot un convidat sorpresa de darrera hora que ens dona la data del primer vermut golfaire del any. Va, de debò, deixa de llegir i escolta el PUGRAMA 103!! Han Sonat: Marvin de la Croix, Bonitx, Gazella, Montesco, Drug Holiday, Roko Banana, Secondbest, Slow Connection, Vecinos, Alcalá Norte, Leon Guallart, A Woman Dressed in Green i Triana.

Corrientes Circulares
Corrientes Circulares 14x18 con PHOENIX, RUFUS T. FIREFLY y más

Corrientes Circulares

Play Episode Listen Later Feb 25, 2024 62:33


Corrientes Circulares 14x18 con noticias y novedades sobre Besmaya & Sidonie, Rufus T. Firefly, El Último Vecino, Love of Lesbian & Turf, R.E.M., Deleste Festival, Gazella, Tomavistas Festival, Phoenix, Nena Daconte & Alberto (Miss Caffeina), Carlangas & Los Cubatas, La Bien Querida y Hot Chip!!! Dale al play!!!

Corrientes Circulares
Corrientes Circulares 14x18 con PHOENIX, RUFUS T. FIREFLY y más

Corrientes Circulares

Play Episode Listen Later Feb 25, 2024 62:33


Corrientes Circulares 14x18 con noticias y novedades sobre Besmaya & Sidonie, Rufus T. Firefly, El Último Vecino, Love of Lesbian & Turf, R.E.M., Deleste Festival, Gazella, Tomavistas Festival, Phoenix, Nena Daconte & Alberto (Miss Caffeina), Carlangas & Los Cubatas, La Bien Querida y Hot Chip!!! Dale al play!!!

Corrientes Circulares
Corrientes Circulares 14x18 con PHOENIX, RUFUS T. FIREFLY y más

Corrientes Circulares

Play Episode Listen Later Feb 25, 2024 62:33


Corrientes Circulares 14x18 con noticias y novedades sobre Besmaya & Sidonie, Rufus T. Firefly, El Último Vecino, Love of Lesbian & Turf, R.E.M., Deleste Festival, Gazella, Tomavistas Festival, Phoenix, Nena Daconte & Alberto (Miss Caffeina), Carlangas & Los Cubatas, La Bien Querida y Hot Chip!!! Dale al play!!!

Songhunter
Immersos al dream pop on

Songhunter

Play Episode Listen Later May 28, 2023 30:58


El quintet valenci

Songhunter
Immersos al dream pop on

Songhunter

Play Episode Listen Later May 28, 2023 30:58


El quintet valenci

Könyvpáros
2022 és 23 könyvekben, Margaret Atwood - Guvat és Gazella

Könyvpáros

Play Episode Listen Later Jan 10, 2023 44:28


[0:09] Karácsony, ovis kolera [2:36] 2022, 2023: mit hagyunk el, mi az amin javítunk, olvasási stratégiák [13:42] Margaret Atwood: Guvat és Gazella Két hét múlva -> Kövi Pál: Erdélyi lakoma újratöltve (szerk: Cserna-Szabó András) Négy hét múlva -> Marcus Aurelius: Elmélkedések (letölthető a mek.oszk.hu-n) Instagram: Könyvpáros Twitter: doublingcube, csiporog

The Folks Back Home
Tom Gazella

The Folks Back Home

Play Episode Listen Later Apr 26, 2022 80:06


Mr. Tom Gazella spent over 30 years as a Buchanan High School guidance counselor and English teacher, and 40 years behind the scorer's table at the basketball games. Mr. Gazella was a beloved figure in the halls of BHS and continues to mentor his former students, even years after his official retirement. In this episode, we take a walk down memory lane and discuss how Mr. G got to Buchanan in the first place, what it was like being a part of such a legendary crew of teachers, and what he's been up to since leaving his classroom. Spoiler alert, he hasn't slowed down…at all. If you were around Buchanan in the last 40 years, you're going to love this episode and the stories he shares. Support this show with a $3 donation at buymeacoffee.com/folksbackhomeSupport the show (https://www.buymeacoffee.com/folksbackhome)

Showgirl’s Life Podcast
Launching from the hotseat

Showgirl’s Life Podcast

Play Episode Listen Later Jul 4, 2020 23:08


This episode is the introduction to the host of Showgirl's Life podcast, Athena Patacsil, aka Gazella. Learn about her path to becoming a Las Vegas Showgirl, why she began this podcast, and sneak peeks to future episodes.

Natural Medicine Journal Podcast
Covid-19 Shines Light on Existing Healthcare Disparities

Natural Medicine Journal Podcast

Play Episode Listen Later May 5, 2020 11:23


African Americans and other people of color throughout the United States are suffering disproportionately from Covid-19. In this interview, Udaya Thomas, MSN, MPH, APRN, CYT, talks about how integrative practitioners can better serve the health needs of underserved populations during this pandemic. Thomas is an integrative primary care nurse practitioner and the board president of Integrative Medicine for the Underserved, a nonprofit organization of multidisciplinary practitioners committed to affordable, accessible integrative healthcare for all. About the Expert A. Udaya Thomas, MSN, MPH, APRN, CYT, is a board-certified nurse practitioner in primary care and practices integrative medicine in a Safety-Net hospital system for the underserved in Southeast Florida at Memorial Primary Care. She is also pursuing her PhD in nursing at Walden University’s interdisciplinary health track, focusing on the integration of behavioral health in primary care. Udaya is also the board president of the non-profit organization Integrative Medicine for the Underserved (IM4US). Disclosure: Thomas is partially funded by Grant #5T06SM060559-07 of Substance Abuse Mental Health Service Association (SAMHSA) American Nursing Association (ANA) Minority Fellowship Program (MFP). SAMHSA is a government resource for practitioners and the ANA MFP is currently accepting applications for more minority fellows. Transcript Karolyn Gazella: Today, our topic is serving the healthcare needs of underserved populations. We'll also discuss the fact that African Americans and other people of color are suffering disproportionately from Covid-19. Hello, I'm Karolyn Gazella, your host and the publisher of the Natural Medicine Journal. My guest is integrative primary care nurse practitioner Udaya Thomas. Udaya presently works in a safety net hospital system for the underserved in Southeast Florida at Memorial Primary Care and she is also pursuing her PhD in nursing. Udaya, thank you so much for joining me. Udaya Thomas: Thanks for having me Karolyn. It's great to be with you and thanks also to my colleague Priscilla Abercrombie, Past President of IM4US for connecting us. Gazella: Yes, that's great. Yeah. Now before we jump into our topic, tell us a little bit about your present clinical work at Memorial Primary Care. Thomas: Well, I work as a primary care nurse practitioner in a patient-centered medical home, and actually for the past 5 weeks instead of person care, we've had to go virtual with Covid-19 pandemic, but our administration led us into a quick change and we're doing 100 percent telehealth encounters. Patients can also message me directly to give them access to me whenever they need it. Gazella: That's great. Now, where does your interest in healthcare disparity spring from? Thomas: I would say from growing up as a first-generation Indian immigrant in a low-resource rural community, I've always actually been interested in integrative approaches. So I chose nursing and public health as my path to work for the underserved in this country. Gazella: That's great. So you're the president of Integrative Medicine for the Underserved, also known as IM4US. Tell us a little bit about that organization. Thomas: IM4US is a nonprofit organization of multidisciplinary practitioners who are committed to affordable, accessible, integrative health for the underserved. IM4US is the only integrative health organization focused solely on the underserved, which makes us fairly unique. We support practitioners that serve underserved populations to outreach, education, research, and advocacy. We also have equity, diversity, and inclusion principles for all the work that we do. And while we typically have an in-person annual conference, due to the coronavirus precautions, we've moved our 10th annual conference to a virtual conference. Our underserved communities have been specifically affected by the crisis, not only because they're more likely to be susceptible to getting ill, but being out of work for this long really puts them at risk by not having an income, leading to less resources and poor health outcomes. Gazella: Yeah, and I want to talk about that in a little bit more detail because right now, given the data that we've received presently more African Americans and other people of color throughout the United States are dying of Covid-19 compared to Whites. Now this crisis is really shining a bright light on existing healthcare disparity. So from your perspective, what is the present Covid-19 crisis telling us about this huge healthcare gap that exists in this country? Thomas: There's so many factors. As Dr. Zwickey mentioned and at the end of your last podcast with her, the coronavirus pandemic has really turned on a loudspeaker to how many disparities there really are. Studies have shown that social determinants of health are responsible for on average 50% of people's health outcomes. For example, The Hill published last week that African Americans are 6 times more likely to die than their white counterparts in Chicago. Yesterday morning, Governor Cuomo commented on CNN, the new rise in Latino cases and deaths in New York. Suffice it to say that comparative to their percentage in the population, minorities are greatly affected and dying at a much higher rate. Current estimates as you might know, are up to 70% areas with concentrated low-income minorities. So is it their racial background or ethnicity that puts them at risk? Well, in the case of coronavirus and most illnesses, actually no. Rather, it's poor social determinants of health, the lack of employment, safe and stable housing, literacy level, and access to healthy food options that determine health outcomes. These determinants are responsible for most health inequities, as well as lack of access to equitable care. For example, Karolyn, a New York hospital was recently highlighted in the lower-income part of town that is struggling with fewer resources compared to wealthier areas. It's a systemic issue. Because of all the challenges and sometimes trust issues, minorities may delay seeking care too. At IM4US we help practitioners attempt to level the playing field by offering low-cost solutions and increase access to integrative modalities and care and to increase trust. We also provide members opportunities to get involved with educational and policy initiatives to support the underserved. Gazella: Yeah, I love that about your organization and it's going to be especially interesting for our listeners and readers because they already practice integrative medicine. So the fact that they can take their medicine and now serve the underserved, I think it's really a cool thing. And you know, you mentioned that 70% of deaths that studies showed that even though 70% of the deaths were in African Americans, African Americans only represented 32% of the population. So that is a really big healthcare disparity issue that we have. Now, as you mentioned, it is a systemic issue and it's clear that it needs to be addressed systemically. But what can integrative practitioners do to help ensure that they're not contributing to the problem or perpetuating healthcare disparity issues in their clinical practice? Thomas: Mm-hmm (affirmative) Great question, Karolyn. While there are many things that practitioners and specifically integrative practitioners can do, but just to mention a few really important things that could make a great impact. One, they can do implicit bias training. This is a free training and it's online and it allows practitioners to find out their own biases as we all have them, whether we work for the underserved or not. Secondly, practices if they don't already have one, can try to secure a legal aid attorney to offer low-income patients legal advice and representation when facing issues like discrimination or eviction for example, and third, they can join our movement. IM4US promotes groups as a way to build trust and increase access to integrative care. In light of the current crisis, we're recommending telehealth groups whether in the time of Covid-19 or not, we can also offer medical group visits via telehealth. It's a great way to connect patients, HIPAA-compliant consent of course together with care team members to increase social connection, reduce loneliness, anxiety and fear that the public is currently living with. Gazella: Yeah, that's true. What about people who may not have internet access? Does the telehealth visits still work? Thomas: Great question. Actually we are putting together some continuing education for our upcoming conference and on that specific topic because we want to address access to everybody. I know actually that even when I do telehealth visits just with family members together, hearing multiple voices together and knowing that they're connected to their practitioner and their care team, whether through telephone or through video really makes their spirits lift and a sense of relief that they had contact with you. And you're right, many don't have high internet speed or access to join by video, but making group chats available is also helpful and just knowing someone is on the other line can save a life. Gazella: Yeah. Like when you mentioned in the very beginning that your patients actually have access to you and they can message you. That's huge. And I would think that that would be a big part of their healing and a part of their care. Now, where can people find more information about IAM4US? Thomas: Well, we have a website and I'll give you the address. It's www.im4us.org. Gazella: Perfect. We'll also put a link to that website on our Natural Medicine Journal site so people can just click over and find access. It's a great organization, lots of resources, and really doing some good work to help underserved populations. So Udaya, thank you so much for joining me today. Thomas: You're welcome, Karolyn. We've been around for about 12 years, so we're still considered somewhat young, but like I said, we're having our 10th anniversary this year and we're really excited to have more of the community join us. Gazella: Yeah, absolutely. Well, happy anniversary- Thomas: Thank you. Gazella: … and this is a conversation that we're going to keep going. I think it's such an important one. You know we provided some good information, but let's just keep talking about it. I think this is very, very important. I also want to remind listeners that you can find all of our past podcasts at naturalmedicinejournal.com. Today I mentioned the ones that I've done with Dr. Zwickey on Covid-19. But we have lots of information at naturalmedicinejournal.com and our podcasts are also available on Pandora, Spotify, iHeartRadio, iTunes, and many other podcast outlets. So thanks for listening everyone and stay safe.

Natural Medicine Journal Podcast
Climate Change and Food Quality

Natural Medicine Journal Podcast

Play Episode Listen Later Aug 22, 2019 13:04


Natural Medicine Journal publisher Karolyn A. Gazella talked with Kristie Ebi, PhD, from the Center for Health and the Global Environment with the University of Washington. The two discuss Ebi's research using new technology to model growing conditions as they will be in the coming decades if we don't curb climate change.

SER Runner
Gazella: la primera app de entrenamiento pensada para mujeres

SER Runner

Play Episode Listen Later May 31, 2019 15:29


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento

SER Runner
SER Runner: Gazella, la primera app de entrenamiento pensada para mujeres (31/05/2019)

SER Runner

Play Episode Listen Later May 31, 2019 39:59


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento. Además, os proponemos dos citas: una milla en Córdoba y una carrera de trail por la costa de Bizkaia

SER Runner
SER Runner: Gazella, la primera app de entrenamiento pensada para mujeres (31/05/2019)

SER Runner

Play Episode Listen Later May 31, 2019 39:59


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento. Además, os proponemos dos citas: una milla en Córdoba y una carrera de trail por la costa de Bizkaia

SER Runner
Gazella: la primera app de entrenamiento pensada para mujeres

SER Runner

Play Episode Listen Later May 31, 2019 15:29


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento

SER Runner
Gazella: la primera app de entrenamiento pensada para mujeres

SER Runner

Play Episode Listen Later May 31, 2019 15:29


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento

SER Runner
SER Runner: Gazella, la primera app de entrenamiento pensada para mujeres (31/05/2019)

SER Runner

Play Episode Listen Later May 31, 2019 39:59


Hablamos con los creadores de esta aplicación ya disponible para dispositivos Android que tiene en cuenta las fases del ciclo menstrual a la hora de elaborar nuestros planes de entrenamiento. Además, os proponemos dos citas: una milla en Córdoba y una carrera de trail por la costa de Bizkaia

Natural Medicine Journal Podcast
Probiotics and Cancer Prevention: A Conversation with Ross Pelton, RRh, CCN

Natural Medicine Journal Podcast

Play Episode Listen Later Oct 23, 2018 32:20


In this podcast episode, we speak with Ross Pelton, RRh, CCN, about the variety of mechanisms of action that probiotics have when it comes to reducing cancer risk. Pelton also talks about colon cancer, H. pylori, and probiotic safety and dosage. Finally, he describes how to support a healthy microbiome with a healthy lifestyle. (Approximate listening time is 32 minutes) About the Expert Ross Pelton, RPh, CCN, is Essential Formula's director of science, in addition to being a practicing pharmacist, clinical nutritionist, and health educator in Southern Oregon. Pelton earned his bachelor of science in pharmacy from the University of Wisconsin. A certified clinical nutritionist, Pelton was named as one of the Top 50 Most Influential Pharmacists in the United States by American Druggist magazine for his work in natural medicine. Pelton teaches continuing education programs for healthcare professionals to use natural medicine and integrate it into their practices. He also has authored numerous books, including The Drug-Induced Nutrient Depletion Handbook, which is a gold-standard reference book for health practitioners. About the Sponsor Essential Formulas Incorporated (EFI) was established in 2000 as the sole US distributor of world-renowned microbiologist Dr. Iichiroh Ohhira’s award-winning probiotic dietary supplements and skin care products. Always an innovator, EFI introduced REG’ACTIV in 2015, containing ME-3, a probiotic catalyst that produces the “master’” oxidant glutathione inside the body's cells. A family-owned and operated business, EFI was founded on the philosophy of providing high-quality preventative, supportive, and comprehensive pro-health products for the entire family. EFI continues to flourish and grow through a strong company and product integrity and the knowledge that they’re providing scientifically proven products that positively impact the health and well-being of their customers. Transcript Karolyn Gazella: Hello. I'm Karolyn Gazella, the publisher of the Natural Medicine Journal. Today, our topic is reducing cancer risk with probiotics. Before we begin, I'd like to thank the sponsor of this interview who is Essential Formulas Incorporated. My guest is integrative pharmacist and nutritionist Ross Pelton who is an expert on the topic of probiotics and health. Ross, thank you so much for joining me. Ross Pelton, RPh, CCN: Hi, Karolyn. It's really nice to be with you. I enjoy our conversations. Gazella: Yes. Now, first of all, how does the scientific literature stack up when it comes to probiotics and cancer prevention? Are there published human clinical trials? Pelton: Well there's really not a lot of human clinical trials, but there's really quite a bit of research that has been conducted looking at cancer with probiotics. Human clinical trials are lacking, but there's a lot of work that has been done, cell culture studies and animal studies. There's a lot of work being done in this area. We just don't have the longterm human clinical trials which are very expensive to do. I think there's a lot to talk about because we've got substantial studies that have been published on the relationship between probiotics and cancer. Gazella: Right. So I'd like to begin by having you give us an overview of exactly how probiotics influence the microbiota to reduce cancer risk. Now, there are several mechanisms of action. So go ahead and fill us in. Pelton: Sure. Well some of your probiotics produce compounds that have antioxidant activity. Some of them have anti-inflammatory activity. They help to regulate detoxification. A lot of these functions are due to the fact that your probiotic bacteria produce secondary compounds or secondary metabolites that are called postbiotic metabolites. This is really the new frontier in microbiome science, starting to learn more about the compounds that your probiotic bacteria produce when they digest and ferment the food that you give them. Remember, these compounds have anticancer activity or protectant mechanisms that help protect against cancer. Gazella: So I'd like to focus on these mechanisms of action as they relate to reducing risk of cancer. So let's begin with a more well-known mechanism and that is, as you mentioned, probiotics influence immunity. Describe what the scientific literature tells us about probiotics and the immune system. Pelton: Well we know that 70% to 80% of the cells in your immune system reside in the gut. So it's really critical to have a healthy microbiome, a healthy gastrointestinal tract because that is the bulk of your immune system cells. One thing a lot of people don't realize is in the first 6 months of life, the primary function of your probiotic bacteria is to train your immune system. So it's really critical that kids get a good start in life with a vaginal delivery and adequate breastfeeding and for kids that don't, that's a compromised immune system. The gut is the seat of the immune system, and your probiotic bacteria are what trains the immune system. Gazella: So now, what about maybe a little less known activity which is, as you mentioned, the antioxidant potential of probiotics? This may not be on the radar of some practitioners. Describe this mechanism of action. Pelton: Sure. We know that free radical damage causes DNA damage and can increase your cancer risk. In a highly inflammatory condition in the gastrointestinal tract, there's a lot of free radicals being produced and a number of your probiotic bacteria have antioxidant activity and they also produce compounds that have antioxidant activity. There's 2 things going on here. Some of the bacteria themselves are antioxidants, but more importantly, they produce compounds that have direct antioxidant activity. In that respect, they're reducing free radical damage and reducing cancer risk especially for colon cancer which is a site of a lot of the free radical activity in a highly inflamed colon. Gazella: Yeah. We're going to definitely talk about colon cancer, but now, when it comes to this influence on immunity and antioxidant potential, are there research studies in vivo or in vitro studies indicating probiotics, which probiotics can help with immunity and antioxidant potential? Pelton: Sure. There's both some of the lactic acid-producing bacteria, Lactobacillus strains, and also some of the Bifidobacteria, bacteria that reside primarily in the large intestine and colon. One of the classes of antioxidants that they produce, they're called exopolysaccharides. That's a big word for people, but it just means that there are chains of sugars that the bacteria produce and then they excrete them and they have antioxidant activity. So this is just one of the mechanisms of action by which both Lactobacillus and Bifidobacteria are able to produce antioxidant compounds that reduce cancer risks. Gazella: So the research tells us that probiotics can influence gene expression. Tell us how this impacts cancer risk reduction. Pelton: Well various different strains of probiotic bacteria can influence gene expression. They can influence apoptosis, which is the rate of cell death. They can influence metastasis. They can influence cancer stem cells. They can up-regulate tumor suppressor genes. So a number of different ways that probiotic bacteria and the compounds that they produce, these postbiotic metabolites can influence gene expression which ultimately is going to influence cancer risks. Gazella: So now, there's a significant amount of evidence and research showing that toxins can increase risk of cancer. What role do probiotics play in neutralizing some of these toxins or in supporting the detoxification of some of these toxins? Pelton: Sure. This is actually a pretty broad category. There's a lot of different ways that probiotics can have detoxification capabilities. Some strains of bacteria can detoxify or decrease the absorption of a cancer risk factor called bisphenol A. There's a lot of studies on that substance now that show that it increases cancer risk. This is a compound that's in a lot of products that are on the market, especially baby products. Some strains detoxify some of the agricultural pesticides. One of the Essential Formulas' products, Reg'Activ, contains a strain of bacteria called Lactobacillus fermentum ME3, and that strain of bacteria up-regulates a group of enzymes called paraoxonase enzymes. Those enzymes directly detoxify things like organophosphates, which are one of the commonly used pesticides in the agricultural industry. Other strains can directly bind some of the heavy metal toxins like mercury and lead and cadmium. They also decrease the absorption of these heavy metal toxins when they bind them up so they don't get absorbed into your system. They get excreted. Some strains actually metabolize cancer-causing food preservatives like sodium nitrate, and Bifidobacteria are able to degrade and detoxify a very serious compound called perchlorate. We get exposed to perchlorate from fertilizers in the environment and a lot of that in the agricultural industry. Heterocyclic amines are frequently caused by cooking meat at high temperatures. So our middle America, meat and potato people, they're out there with their barbecues and they're producing these heterocyclic amines. Some of the Lactobacillus organisms reduce the toxicity from heterocyclic amines. That's just a number of the different ways that your probiotic bacteria function as detoxifying agents in the gastrointestinal tract. Gazella: Yeah. It's a long, impressive list. Now, I want to get back to the ME3 that you mentioned. Are there scientific studies on that particular- Pelton: There are. Gazella: ... strain, the ME3? Pelton: It is a really, really fascinating topic because Lactobacillus fermentum ME3 synthesizes glutathione. Glutathione is the master regulator of your detoxification throughout your system and every cell produces glutathione, but it's hard to boost your levels of glutathione because, when you take it orally, it gets oxidized, it gets broken down and destroyed so you don't absorb it. But now we've got a strain of bacteria, this Lactobacillus fermentum ME3, where the bacteria actually synthesize glutathione. Yes, we have human clinical trials showing that the antioxidant activity of glutathione produced by the ME3 probiotic bacteria will reduce levels of oxidized LDL cholesterol so you're reducing your cardiovascular risk, and it does a good job of increasing detoxification throughout your whole body. The human clinical trial, people taking ME3 had an astounding 49% increase in the ratio between oxidized glutathione to reduced glutathione with the reduced glutathione is the active form. A 49% increase in the ratio of the reduced to oxidized glutathione is a huge, huge meaningful marker. This is really a revolution in healthcare and medicine to be able to boost your glutathione levels on a regular basis because, as I mentioned, glutathione regulates your detoxification. It's also called the master antioxidant and probably protects more of your body than all the other antioxidants combined. This is one area that is just really astounding both in terms of antioxidant protection and detoxification capabilities. Gazella: That's great. So I'd like to switch gears and I'd like to talk about specific cancers. When I think about probiotics and cancer, I often think about colon cancer. You mentioned that previously. What role can probiotics play in reducing the risk of colon cancer? Pelton: Well there's a number of ways that this can happen. Pathological bacteria will convert bile acids into secondary metabolites that promote cancer. When you have the proper acid-base balance in the GI tract, there's a dramatic reduction in the conversion of these bile acids into the more cancer-causing secondary metabolites. So maintaining the proper acid-base balance, which is what the probiotic bacteria do when they produce things like short-chain fatty acids and organic acids and nucleic acids, they create the proper acid-base balance which reduces the conversion of bile acids into secondary cancer-causing metabolites. Your probiotics can also inhibit the activity of carcinogenic enzymes. They suppress growth of bacteria that produce enzymes that deconjugate carcinogens. What I mean by that is that a lot of carcinogens get bound up and they're supposed to be excreted when you have bowel movements, but if you don't have good elimination and so things stay in the colon too long, those cancer-causing things that are bound up can get released and reabsorbed. So probiotics can actually suppress the growth of bacteria that produce these enzymes that are deconjugating these carcinogens. Good bacteria are actually keeping these carcinogenic byproducts bound up so they get eliminated from your body. Gazella: Well speaking of bacteria, it's widely known that there's a connection between H. pyloriand cancer. Can you describe that connection and tell us how probiotics can help prevent or even reverse H. pylori? Pelton: Sure. That's another big topic because now that H. pylori has been discovered and understood, we realize it's the primary cause of stomach cancer and cancers in the upper small intestine. This is an interesting bacteria. It's got kind of a corkscrew tail on it, and it can just burrow its way into the lining in the stomach or the lining in the small intestine. When that happens, you've got a hole in your intestinal wall. Then you get the acids and the digestive enzymes leaking through, creating inflammation, and you end up with a higher incidence of cancer. If you have a good, healthy microbiome and adequate numbers of your good bacteria, you suppress the growth or the overgrowth of H. pylori. There's a little bit of a controversy about whether people should try to totally eradicate H. pylori. Some people, some of ... Martin Blaser is one of the leading scientists that's exploring this and saying maybe we shouldn't totally eliminate H. pylori, but people that have H. pylori overgrowth certainly do have increased risk to gastric cancer and small intestinal cancers. It's having a good microbiome and adequate numbers of your good bacteria that will keep the H. pylori in check and not get overgrown so you reduce your cancer risk. Gazella: What are some of the symptoms of H. pylori overgrowth? I mean how does a doctor recognize this in their patient population? Pelton: Well as I described, the bacteria has this corkscrew tail that burrows through the unprotected mucus lining in your stomach or your small intestine. When you get that hole in the lining, you've got an ulcer. It's painful. Your digestive acids, your stomach acid, and your bile acids and small intestine. Then they go through the mucus membrane which is your protective barrier, and they come into direct contact with the cells that line your GI tract. When that mucus protective layer is breached, then those acids contact those cells that line the GI tract and it's painful. You've got an ulcer and you say "Oh, man. This is sore." So people actually oftentimes stop eating because every time they eat, they get more digestive juices in that ulcerative location. You need to heal that ulcer. Getting rid of H. pylori is one thing, but you also have to take time to heal the ulcer. Gazella: Yeah, that makes a lot of sense. Now so far, we talked about colon cancer, stomach, upper GI. Are there any other cancers when it comes to using probiotics? I mean do you pretty much recommend probiotics as a risk reduction strategy across the board? Pelton: I do because your immune system is so directly related to cancer risk factors. A lot of people don't realize that probiotics have an effect outside the intestinal tract. We now know that things like short-chain fatty acids get absorbed into your system and can actually reduce the risks of liver cancer. It's a whole body effect. These bacteria are not just a local effect in the gastrointestinal tract. I kind of use the analogy of Mission Control at NASA where those computers are controlling your space flights. Well your probiotics and the postbiotic metabolites in your small intestines and your colon are really Mission Control for all health-regulating effects in your whole body. There's a new study that I wanted to share with you, Karolyn, published just recently in a journal called Oncotarget. It's a cancer journal. It says cancer killers in the human gut microbiota. One of the things they're reporting here is that they identify intestinal bacteria that exhibit potent antimalignancy activities on a broad range of solid cancers and leukemia. So this is a relatively new paper just published in July of 2017, identifying that postbiotic metabolites and your probiotic bacteria are helping to reduce both solid cancer tumors and leukemia. It's just an exciting new report giving more emphasis on the anticancer capabilities of your probiotic bacteria. Gazella: Yeah. I think this area of research is going to just really explode. Now, a lot of patients go into their doctor's office and they say "Oh, well I'm fine. I don't need a probiotic supplement because I eat yogurt everyday," or something like that. How easy or difficult is it to get the probiotics we need from diet alone? Pelton: It depends on what you mean by diet. If people are eating fermented foods, that's a really good source of probiotic bacteria, but most people aren't eating sauerkraut and kimchi and tempe and things like that. Most foods don't have probiotic bacteria. People think about yogurt, but commercial yogurts have a lot of sugar which actually promotes the growth of your pathological bacteria and yeast like candida. So commercial yogurts are generally not a good idea either in terms of just not getting a good source of probiotic bacteria. You're really working against the health of your gastrointestinal tract and your microbiome. If people produce their own yogurts, there are some good ones. Yes. But you're really not getting a diverse level of bacteria in yogurt, and a healthy microbiome is a diverse microbiomes which means you want to get a lot of different types of strains of bacteria. The best way to do that is to consume a diet that has many different types of fiber-rich foods, especially the multicolored vegetables. That's the number one food source for your bacteria. Gazella: Right. We have to feed those good bacteria. Pelton: That's right. Gazella: So now, you represent a specific type of probiotic, the Dr. Ohhira's brand. Why do you recommend that specific brand of probiotic? Pelton: Well I'm glad you asked that. I'm the scientific director of Essential Formulas, and Dr. Ohhira's Probiotics is our primary product line. Dr. Ohhira's Probiotics are made differently than every other probiotic in the world. In fact, it's kind of confusing, but Dr. Ohhira's Probiotics is really not primarily a probiotic. It is primarily a fermented food. The Dr. Ohhira's Probiotics are produced in a fermentation production system. We have large fermentation vats in a warehouse, and we start with 12 strains of probiotic bacteria. Then at seasonally appropriate times throughout the year, we shred and harvest dozens of different types of organically-grown foods. There's fruits and vegetables and mushrooms and seaweeds. Then the bacteria get to digest and ferment these foods for 3 years before the product is finished. During that fermentation process, the bacteria are breaking down the foods and producing this wide range of compounds that we now refer to as postbiotic metabolites. As I mentioned earlier, these are the master health-regulating compounds in our system. So Dr. Ohhira's Probiotics have been tested and we find out there are over 400 postbiotic metabolites in Dr. Ohhira's Probiotics. We are not primarily just delivering probiotic bacteria. We're delivering over 400 of these postbiotic metabolites that rapidly create change in the GI tract. You rapidly reduce inflammation, rebalance the acid-base level, promote the growth of healthy new cells that line the GI tract, cell signaling and gut-brain communication directly with postbiotic metabolites. We get what we call rapid microbiome restoration or rapid microbiome repair. Other companies are just giving you bacteria in a capsule. That's kind of like a starter culture. Those bacteria haven't done any work yet. Our bacteria have been working for 3 years producing postbiotic metabolites by the time you ingest them. That's the big difference. Dr. Ohhira's Probiotics is different than every single other probiotic in the world. The new science in the microbiome, the new frontier in microbiome science is starting to realize that it's these postbiotic metabolites that have the master health regulatory effects in the gastrointestinal tract and health-regulating effects for the entire body. So by directly delivering this postbiotic metabolites, we get rapid improvement in the microbiome in the gastrointestinal tract for people who take Dr. Ohhira's Probiotics. Gazella: Now, I know this particular product does not have to be refrigerated. Why is that? Pelton: Well these bacteria learn to thrive and survive at room temperature during the 3 years of fermentation. They don't need to be refrigerated, which makes them very user-friendly. Also they are in a patented capsule that stays hard in the harsh acid environment in the stomach. Then it preferentially releases the contents in the small intestine. So it doesn't make any difference if you take it with food or on an empty stomach. Any way you take it, just the main thing is 2 capsules once a day. Get Dr. Ohhira's in on a regular basis and you'll be maintaining a healthy microbiome. Gazella: Yeah. I'd like to talk a little bit about dosage because honestly it seems like you can ask 3 different experts about dosage and they'll give you 3 different answers. When it comes to dosage specific to cancer prevention, is that the 2 caps per day? What does that deliver in terms of CFUs or different strains for that two caps per day? Pelton: Well 2 capsules a day is the recommended dosage. One thing we emphasize, we're not concerned about how many million or how many billion bacteria we have. There's a numbers game that is really a misconception by people when we're talking about probiotics that they call the bacteria that are available CFU which stands for colony forming units. It really means just the number of viable bacteria, but people have a misconception that more is better. They say "Mine has 30 billion. Mine has 50 billion. Oh, mine's got 100 billion." They think more is better. One of the most critical factors in a healthy microbiome is balance. If you take massive doses even as a healthy strain of bacteria, you're not working in favor of balance. You're actually working against creating balance in the microbiome. So it's not important to have high strains of, high dosages and high numbers. It's better to have a multistrain probiotic, a lot of different strains but at lower dosage levels. I really talk in my lectures and seminars against the high-dose probiotics. I'm not saying they're never appropriate. A product like VSL3, which is a prescription probiotic, I think it has 112 billion bacteria per dose. Those people have some good research and have documented benefits from their high-dose probiotic, but I don't think high-dose probiotics are appropriate on a longterm maintenance basis. You want to strive for balance and diversity. Gazella: Yes, I would agree with that. How many strains are in the Dr. Ohhira's product? Pelton: Dr. Ohhira's has 12 strains. We start out with 12 strains in the manufacturing process. We are a multistrain probiotic. I'm not sure, but Dr. Ohhira may have been the first scientist in the world to understand the concept and the importance of a multistrain probiotic because he created Dr. Ohhira's Probiotics 30 years ago. Gazella: Yeah. So let's talk a little bit about safety. When it comes to cancer prevention, are probiotics safe for the majority of patients or is there any patient or group of patients who should not take probiotics to help reduce cancer risk? Pelton: No, everybody should take probiotics. One of the most important things for health is a healthy microbiome. We now understand that a healthy microbiome is the foundation of health. I think it's important for everybody to realize that supporting and maintaining a healthy microbiome is a critical factor for health regulation. There's no contraindications. I do want to mention briefly, Karolyn, there are 2 studies that were recently published in the journal Cell that have gained a great deal of publicity because they cast doubt on the effectiveness of probiotics. The scientists who conducted these studies stated that their results suggested probiotics are almost useless. There's been a lot of pushback after the publication of these studies. It turns out there was some methodological shortcomings in the way they set up their studies, and there were a very low number of people. I think there was only 8 to 12 people in these studies. What's more disturbing is that it has been learned that the scientists that conducted these studies, they have a personalized approach to probiotics that they promote in their studies. Turns out that they have a vested interest. They have financial interest in this company that's promoting this personalized approach. So it's a very serious flaw and their conclusions should not be generalized of the whole field of probiotics. Allowing studies to be published in which the authors state that probiotics are almost useless is really grossly misleading and a disservice to the general public. Gazella: Yes, I would agree. Now, I often like to ask experts to grab their crystal ball and look into the future. In your case, I'd like to have you tell us what you'd like to see happen when it comes to probiotic or postbiotic metabolite research in the future. What do you want to see happen as we go into this next phase? Because I'll tell you, there's a lot of exciting stuff happening. There's a lot of different directions we could go into. Pelton: You're absolutely right. It is a very exciting field and rapidly evolving. As I've talked about these postbiotic metabolites, the compounds that your probiotic bacteria produce, in the future, we will learn a great deal more about the health-regulating effects of these compounds that your bacteria produce and we'll learn more about which strains of bacteria are more effective at producing some of these health-regulating postbiotic metabolites. I think in the future, we'll probably make a great deal of inroads and progress in designing personalized probiotic programs for people. We'll be able to assess your own innate microbiome and be able to know more accurately how to promote and enhance the growth of your own innate what we call your probiotic fingerprint, the bacterial population that you've developed early in life. I think we'll get into more of a personalized microbiome and personalized approach to probiotics to help promote health in individuals. Gazella: When you think about cancer specifically and reducing cancer risk, I mean now obviously, it's estimated that 1 in 2 men and 1 in 3 women will develop cancer in their lifetime. I mean this is now reaching near epidemic proportions. How critical is it that we look at things like probiotics when it comes to reducing cancer risk? Pelton: Well again, I go back to the immune system. It's absolutely essential that people have a healthy microbiome so that they have a healthy immune system. This is really where it starts. Your gastrointestinal tract and your microbiome are literally the foundation of your health for everything that happens. It is the number 1 thing that people need to be aware of and it's not just the microbiome. As we mentioned earlier, you have to learn how to feed your probiotic bacteria well. This is another key message of mine. This is why diet is so important because you're not eating just for yourself. You're eating to feed 100 trillion guests. It's a pretty big party that's going on down there. Every time you eat, you have to realize that you're feeding your microbiome, and your microbiome is the center and the foundation of your health and your immune system and your anticancer activity. So people need to realize how important it is on a regular basis to eat a wide range of different types of fiber-rich foods, especially the multicolored vegetables, because a more diverse fiber-rich diet will promote the growth of a more diverse microbiome which means your bacteria will produce a wider range of these health-regulating postbiotic metabolites and you will be a healthier person with a stronger immune system. There's a recent study that was just published that shows that, reports that people that consume more probiotics take less antibiotics. That's just another insight into probiotics being able to support your immune system. So these people using probiotics more have a stronger immune system. They have less need over time for antibiotics. Gazella: Yeah. That antibiotic issue, that's something that we ... That could be whole other topic for us. Pelton: It's a big one. Gazella: But as an integrative pharmacist, you share a philosophy with our listeners who are, most of them are integrative practitioners. It's not just about giving a pill and calling it a day. It's a very comprehensive approach, and I like the fact that you focus so heavily on diet and using a healthy diet to feed the probiotics and the bacteria and that you use probiotics hand-in-hand with that comprehensive lifestyle approach which I'm assuming, beyond diet, you counsel people to exercise and get enough sleep and those other lifestyle factors as well. Pelton: Absolutely. Those are critical factors. There are studies now that show that your probiotic bacteria respond to exercise. Exercise needs to be emphasized. So it's diet and exercise, lifestyle. All these healthy things go into creating and maintaining a healthy individual and having a healthy aging process. It's not just probiotics and it's not just diet as you mentioned. It's exercise and sleep and learning how to avoid environmental toxins. There's lots of things that go into it. Gazella: Right. Treat your microbiome well and it will serve you for a long time to come. Pelton: It will work for you. Absolutely. Gazella: Well great. Well Ross, this has been very informational as per usual. I want to thank you for joining me. Once again, I'd like to thank Essential Formulas Incorporated for sponsoring this topic. Thanks so much, Ross. Have a great day. Pelton: Nice to be with you, Karolyn. Always enjoy speaking with you.

PlanningXChange
PX29 with Gazella

PlanningXChange

Play Episode Listen Later Oct 7, 2017 29:24


In PX29, Jess Noonan and Peter Jewell interview the women behind the Gazella blog and interview project. Gazella has released over 100 interviews primarily of women working in the built environment.

gazella
PlanningXChange
PlanningxChange 29 with Gazella (bloggers in construction)

PlanningXChange

Play Episode Listen Later Oct 6, 2017 29:25


In PX29, Jess Noonan and Peter Jewell interview the two ladies behind the Gazella project. Justine Hadj and Danielle Savio are the dynamic young women behind the Gazella web and blog project. Gazella is an independent online publication offering insights into inspiring females within the built environment. Gazella has released over 100 interviews focusing on the work of women and topical issues in the built environment. Their website is at www.gazella.com.au. We consider them our 'new media' cousins in our parallel endeavours. In the interview, Justine and Danielle explain how Gazella started, how it works and describe their very busy working lives. A fully engaging interview with outstanding and truly inspirational professionals. Music: Intro - 'Walk right up'. Ladi6 Outro - 'Night Time (feat. Line Gottsche)' Borneland & Falcon Punch. Podcast released 7 October 2017. For more details visit www.planningxchange.org

Natural Medicine Journal Podcast
Addressing Male Urinary Incontinence

Natural Medicine Journal Podcast

Play Episode Listen Later Sep 7, 2017 12:23


One in four men over the age of 65 has urinary incontinence, according to the Centers for Disease Control and Prevention. In this interview, men's health expert Ronald Morton, MD, FACS, describes how urinary incontinence is diagnosed and treated. He also provides detailed information about the key medical devices that are available to treat this condition. Approximate listening time: 14 minutes About the Interview Although urinary incontinence is not as common in men as it is in women, it is more prevalent than many people think. According to the Centers for Disease Control and Prevention, one in four men over the age of 65 suffers from it. The underlying causes are often similar in both genders: aging and weakening of the pelvic floor muscles. However, pelvic trauma or prostate disease or surgery can also contribute to the problem in men. Urinary incontinence creates significant quality-of-life issues, so finding effective treatments is very important. In this interview with urologist Ronald A. Morton, Jr., MD, FACS, Natural Medicine Journal’s publisher Karolyn A. Gazella discusses the prevailing treatment options for male urinary incontinence. For some men, pelvic floor exercises alone can provide relief. For others, diet and weight modification are necessary. Others may opt for more advanced interventions, including surgery. Surgical options range minimally invasive to extensive. On the simpler end of the spectrum is the basic urinary sling. In this quick procedure, a sling is inserted to replicate the support lost in previous interventions or trauma. On the other end of the spectrum is an artificial urinary sphincter, which regulates urine flow through a pump. Of course, surgical interventions are not without risks and side effects. Morton addresses those and discusses how to determine whether a patient is a good candidate for surgery. Listen to this interview to learn more about the current treatment options for male urinary incontinence, as well as Morton’s predictions for the future of incontinence treatment. Scroll down for the full transcript. About the Expert Ronald A. Morton, JR, MD, FACS, is the vice president of clinical sciences for the Urology and Pelvic Health division of Boston Scientific, a position that he has held since August 2015. Before joining Boston Scientific, via acquisition, Morton worked for Endo International plc as chief surgical officer, American Medical Systems. Previously, he worked for GTx, a biotech company in Memphis, TN, as chief medical officer. Prior to joining GTx, Morton was chief of urology at Robert Wood Johnson Medical School and director of urologic oncology for the Cancer Institute of New Jersey. He also held an endowed chair position as director of the General Clinical Research Center. Morton holds a BA in natural sciences from The Johns Hopkins University and received his medical doctorate from The Johns Hopkins University School of Medicine. He has board certification as a diplomat, American Board of Urology. Transcript Karolyn: Hello, I'm Karolyn Gazella, the publisher of the Natural Medicine Journal. Today our topic is male urinary incontinence and my expert guest is Dr. Ronald Morton. Dr. Morton, thank you for joining me. Dr. Morton: Hi, Karolyn, and thank you for having me today. Karolyn: Well great. Well, let's just start with the basics. How is urinary incontinence diagnosed in men? Dr. Morton: Karolyn, urinary incontinence is not as common in men as it is in women, although it does happen more commonly than people think. The main causes are as it is with women, aging and weakening of the pelvic floor muscles. But more importantly, and the reason for many of the interventions that we have for urinary incontinence in men is it can be due to trauma to the male pelvis and/or surgery for diseases of the prostate. When I say disease of the prostate I mean both benign conditions like BPH, which many men suffer from and are aware of, and then also prostate cancer, which is a very common cause for surgery on the male pelvis. Karolyn: And then what's considered the gold standard of treatment for this particular men's health condition? Dr. Morton: There are many ways to treat male incontinence, as there are many ways to treat female incontinence. The usual approach that will be taken by a urologist is to go from the least invasive to more invasive solutions until the patient is happy. I think that one thing that always has to be kept in mind is that this is really a quality of life issue for most men, especially since urinary incontinence in males is generally a disease of men who are older. The median age of diagnosis of prostate cancer is about 63 years of age or so. Since operations on the prostate are the common cause for this, they're generally older men and it's a quality of life issue. What one male will find satisfactory control of the urinary incontinence might be totally unsatisfactory to another. So the general approach would be to start with exercises, commonly called Kegel exercises. The same exercises that we suggest that women do who have a mild degree of urinary incontinence and see if that won't help. If Kegel exercises won't help and it's not something that can be helped with diet and weight modification, then we go into more invasive treatments for male urinary incontinence. The first level of invasion is a procedure that only takes a few minutes, really, less than a half an hour called a male urinary sling. It's much like the slings that are used in women. It  supports the male urethra and holds it up, providing support that has been lost due to the previous surgical intervention or pelvic trauma in hopes that that will correct the incontinence. Fore more severe degrees of incontinence we often times need to move towards what is really considered, as you say in your question, the gold standard for severe incontinence, which is the artificial urinary sphincter [AUS]. In that procedure, a cuff is placed around the urethra and this cuff is connected to a pressure-regulating balloon, which controls pressure in the cuff, keeping the urethra closed and preventing leakage of urine and also a pump, which is placed in the scrotum. When it's time to urinate, the male can just activate the device. The fluid leaves the cuff and goes into the pressure-regulating balloon, opening the urethra. The male can then urinate and then after a period of lock-out time, the cuff will refill, returning him to a state of continence. Karolyn: So let's talk about these two, the sling and the sphincter. What determines whether or not a patient is severe enough for the sphincter versus the sling? What's the difference between those two patients, the one that gets the sling and the one that gets the sphincter? Dr. Morton: Good question because again, it has a lot to do with personal preference. But there are some general guidelines that one can go by. When we measure incontinence and it can be a difficult thing to put a number on, but most men who have incontinence will use urinary pads in their shorts in order to trap urine leaking. A good gauge of to what degree a male leaks is how many times they have to change that pad. Now, some men will as soon as there's a small amount of urine because of the discomfort it will cause will change that pad right away. Some men tend to allow the pad to get very, very soaked before they'll change it. Everyone behaves a little bit differently. A way to get a handle on exactly how much leakage a man has it to do what we call the pad weight test. So we'll give them all the pads that they might need for a day and a bag that can prevent evaporation and they just collect the pads that they use for the day, put it in this bag, and everything is pre weighed, and then we weigh it to see what the volume of urine leakage is. A rule of thumb, if they're leaking around five pads or 300cc of urine a day, that's severe and is more likely to be treated with the artificial urinary sphincter. Degrees of urinary leakage that are less than that can be and generally might be recommended that they be treated with the sling procedure. Karolyn: Now are there are any contraindications associated with each of these options, the sling or the sphincter? So in other words, are there men who would not be a good candidate for either of these options? Dr. Morton: Well, they have to be able to undergo a surgical procedure, and while the sling procedure is relatively short, it does require at least a regional anesthetic. The artificial urinary sphincter procedure is a little bit longer and requires a general anesthetic so they have to be fit for the surgery. The sling is generally not recommended for men if they have been treated for prostate cancer with radiation. The outcomes there haven't been as good as they have been with the artificial urinary sphincter so in that setting we generally would recommend a sphincter as opposed to a sling, even if they were otherwise a good candidate for a sling. Karolyn: What about side effects? Are there any side effects associated with either of these devices? Dr. Morton: I'll take that question separately for each of the two devices. The side effects associated with the sling are that if you don't choose the patient in the best way, two things can happen. One, the patient can not have their incontinence adequately treated. A second issue is if you put a sling in a patient whose major problem is not one of the urethra but is a bladder issue, and that can be sorted out ahead of time with uro dynamics, but if you did you may render that patient obstructed or in urinary retention. The problem doesn't have to do with external sphincter deficiency for that patient. For the artificial urinary sphincter what we're doing is we're placing this cuff around the urethra. It does over time potentially compromise some of the blood supply to the urethra in that area and you can get what's known as atrophy of the urethra in the area of the cuff. When you get atrophy in the area of the cuff there can be a return to urinary incontinence. Of course for both of these procedures, since you're putting a foreign body in, there's a risk of infection, although infectious problems with these devices have been relatively low. Karolyn: Okay, that makes a lot of sense. Now, I'm just curious because you have a certain expertise in this area as chief surgical officer of American Medical Systems. What general advice do you give to physicians who are treating men with urinary incontinence? Dr. Morton: One, most of the advice that I have is for physicians who have men with incontinence but aren't necessarily the experts in treating them. There's a couple of things. One of the things that our research has shown us is that many men who are subjected to surgery for prostate cancer, for example, and who then suffer from incontinence don't recognize, or aren't made aware that there are treatments for it and they suffer in silence we like to say. So, if we can get anything out to the many physicians listening to this podcast it would be don't let this happen to any of your patients. Make sure they understand that if they do get incontinence after, for example, radical prostatectomy, there are options and there are potential solutions for this. The second message is I spend a lot of time working with the engineers and we're constantly looking at ways to come up with a better mouse trap if you will. What can we do to avoid the complications we spoke of earlier? What can we do to help physicians identify the proper patients so we don't use a sling in a patient who should've had an AUS, or an AUS in a patient who should've had a sling? And what can we do to make the functioning of the AUS a little bit easier so that in this elderly population of men they are always candidates for the device? Karolyn: Yeah, that makes a lot of sense and I'm glad that you brought that up about suffering in silence and information. Obviously, a well-informed patient is the best patient to have. So letting that patient know his options is absolutely critical. So one final question for you Dr. Morton. What is on the horizon when it comes to devices for this particular issue with men? Do you see existing devices just being improved? Do you see new devices? Are we kind of where we should be? Look into your crystal ball and tell me what the future holds for this. Dr. Morton: I don't know if I'm the best person to predict the future, but I think that our efforts are to make sure that A, these are the right solutions. We are constantly looking at, are there other options? Are there other ways to manage urinary incontinence? Could we come up with a less invasive way to place the sling or a less invasive device would replicate the great performance of a sling? On the urinary sphincter side of things it's a mechanical device, so can we simplify that mechanism so that it's easier for the patient to implement? Remember there's a patient interface with the AUS. Most devices that we implant, like when a cardiologist implants a pacemaker, there's no patient interface. The patient doesn't have to decide whether or not their pacemakers work. It's in and it just works. For our device, at least for the artificial urinary sphincter, there's that patient interface. So if we can improve that patient interface with the device and make it as reliable as possible, that's what we're looking to do in order to improve the overall performance of the device and have men have a greater satisfaction with their quality of life. Karolyn: Yeah, that makes a lot of sense. Well, this has been very informative. Once again, thank you, Dr. Morton, for joining me today. Dr. Morton: Karolyn, thank you for having me. Karolyn: Have a great day.

Five To Thrive Live
Support During and After Radiation

Five To Thrive Live

Play Episode Listen Later Nov 30, 2016 50:16


Matt Mumber, MD, joins Dr. Lise Alschuler and Karolyn A. Gazella to explain what radiation is, its role in cancer treatment, and how one can support his or her body before, during, and after radiation. Dr. Mumber is a board certified radiation oncologist at the Harbin Clinic in Rome, GA, and the founder of Cancer Navigators, a non profit nurse navigation and educational resource for those touched by cancer.This show is broadcast live on Tuesday's at 7PM ET on W4CS – The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (http://www.talk4radio.com/) on the Talk 4 Media Network (http://www.talk4media.com/).

Natural Medicine Journal Podcast
An Integrative Approach to Enhancing Immunity

Natural Medicine Journal Podcast

Play Episode Listen Later May 9, 2016 28:31


By Karolyn A. Gazella  In this sponsored podcast integrative health expert Russell Jaffe, MD, PhD, CCN, describes a comprehensive approach to identifying immune dysfunction long before illness sets in. He also provides advice regarding diet, lifestyle, and dietary supplements. Jaffe explains why choice is far more significant than genetics and how to counsel patients about reducing immune burden. Approximate listening time: 30 minutes  About the Expert Russell M. Jaffe, MD, PhD, is CEO and Chairman of PERQUE Integrative Health (PIH). He is considered one of the pioneers of integrative and regenerative medicine. Since inventing the world’s first single step amplified (ELISA) procedure in 1984, a process for measuring and monitoring all delayed allergies, Jaffe has continually sought new ways to help speed the transition from our current healthcare system’s symptom reactive model to a more functionally integrated, effective, and compassionate system. PIH is the outcome of years of Jaffe’s scientific research. It brings to market 3 decades of rethinking safer, more effective, novel, and proprietary dietary supplements, supplement delivery systems, diagnostic testing, and validation studies. About the Sponsor PERQUE Integrative Health (PIH) is dedicated to speeding the transition from sickness care to healthful caring. Delivering novel, personalized health solutions, PIH gives physicians and their patients the tools needed to achieve sustained optimal wellness. Combining the best in functional, evidence-based testing with premium professional supplements and healthful lifestyle guides, PIH solutions deliver successful outcomes in even the toughest cases. About the Host Karolyn A. Gazella is the publisher of the Natural Medicine Journal and has been writing and publishing integrative health information since 1992. She is the author or coauthor of hundreds of articles and several booklets and books including her latest book The Definitive Guide to Thriving After Cancer (Ten Speed Press, 2013) that she wrote with Lise Alschuler, ND, FABNO. Together with Alschuler, Karolyn is the cohost of the "Five to Thrive Live!" radio show on the Cancer Support Network and iHeart Radio. She is the co-creator of the Five to Thrive® Plan and the author of "The Healing Factor," a blog on PsychologyToday.com. Gazella is based in Boulder, Colorado.  

Five To Thrive Live
Five To Thrive Live 12/03/2013

Five To Thrive Live

Play Episode Listen Later Dec 8, 2013 51:01


How can spirituality enhance your physical and emotional health, and the health of your relationships? This Five to Thrive Live show delves into the topic of spirit and how we can encourage more joy, laughter, hope, and love in our lives this time of year and all year long. You will discover why the gift of giving is so important, the power of prayer, and how to cope with loss and grief during the holiday season. On this episode, hosts Dr. Lise Alschuler and Karolyn Gazella share significant strategies to have a spirit-filled life.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Five To Thrive Thought Glutathione

Five To Thrive Live

Play Episode Listen Later Dec 8, 2013 2:46


Every morning, your most important antioxidant, glutathione, is naturally at its lowest level. This leaves a window of vulnerability sustaining damage to oxidative stress. This makes it critical to replenish glutathione every day. Listen to this week’s Daily Pulse to learn more about the health benefits of glutathione.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Five To Thrive Thought Exercise

Five To Thrive Live

Play Episode Listen Later Dec 8, 2013 2:21


Discover the most powerful lifestyle strategy to reduce the risk of cancer. You may be surprised to learn that movement, even short bursts throughout the day, can transform the health of our bodies. Listen to this week’s Daily Pulse to learn more about the health benefits of daily movement.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Five To Thrive Thought Color

Five To Thrive Live

Play Episode Listen Later Dec 8, 2013 2:40


The naturally occurring pigments that give rise to the diverse colors of vegetables, fruits and spices are also powerful cancer-fighting compounds. With over 4000 of these polyphenols, plant foods are a literal cornucopia of health benefits. Listen to this week’s Daily Pulse to learn more about the health benefits of eating a colorful diet.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Cancer Prevention Dietary Dos and Don’t

Five To Thrive Live

Play Episode Listen Later Dec 2, 2013 51:31


When it comes to cancer prevention and treatment, are there specific dietary do’s and don’ts? A healthy diet has the potential to lower cancer risk by up to 30%! That is a powerful prevention tool that everyone can use. The question is, “What should I eat?” Learn the most recent information on dietary choices including anti-cancer superfoods such as broccoli and berries, safety of soy foods, fermented dairy, and the cornucopia in farmer’s markets.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Bringing Back Balance Prediabetes Detox

Five To Thrive Live

Play Episode Listen Later Dec 2, 2013 52:16


It may take more than diet and exercise to reverse this disorder. Find out what toxins impact prediabetes and how you can get back on track to conquering this disease. Host Dr. Lise Alschuler interviews expert guest Sarah Cimperman, ND, a practicing naturopathic doctor and author of the book, The Prediabetes Detox: A Whole-Body Program to Balance Your Blood Sugar, Increase Energy, and Reduce Sugar Cravings.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Five To Thrive Live 11/19/2013

Five To Thrive Live

Play Episode Listen Later Dec 2, 2013 50:25


You may not be able to reduce the amount of stress you are under, but what if you could find ways to manage that stress and thrive despite it? On this show, Dr. Alschuler and Karolyn Gazella describe some latest scientific research that has piqued their attention about natural, holistic, effective ways to manage stress. They discuss yoga, diet, vitamins, herbs, and more that can help us protect us from the potential detrimental affects of stress.This show is broadcast live on W4CS - The Cancer Support Network (www.w4cs.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).

Five To Thrive Live
Five To Thrive Daily Pulse Probiotics

Five To Thrive Live

Play Episode Listen Later Nov 9, 2013 2:52


Did you know that many significant health issues can be linked to a key factor? It's true! An imbalance or deficiency of probiotics, the healthy bacteria in our digestive tract, can wreak havoc on our health on so many levels. The long list of symptoms also signifies trouble in the five key pathways which, over time, increases cancer risk. That means that probiotics are critical to supporting the five key pathways for optimal health and cancer risk reduction. Listen to this week’s Daily Pulse to learn more about probiotics.

Tiermedizin - Open Access LMU
Osteomorphological features of the appendicular skeleton of Gazelles, genus Gazella Balinville, 1816, Bohor reedbuck, Redunca redunca (Pallas, 1767), and Bushbuck, Tragelaphus scriptus (Pallas, 1766)

Tiermedizin - Open Access LMU

Play Episode Listen Later Jan 1, 1989


Sun, 1 Jan 1989 12:00:00 +0100 http://epub.ub.uni-muenchen.de/8272/ http://epub.ub.uni-muenchen.de/8272/1/8272.pdf Peters, Joris Peters, Joris (1989): Osteomorphological features of the appendicular skeleton of Gazelles, genus Gazella Balinville, 1816, Bohor reedbuck, Redunca redunca (Pallas, 1767), and Bushbuck, Tragelaphus scrip