ACCP JOURNALS

This podcast episode discusses the economic value of clinical pharmacy services, drawing on a 30-year series of systematic reviews. It highlights the established evidence that these services improve medication use, safety, and effectiveness, while emphasizing the critical need for robust economic evaluations to demonstrate cost-effectiveness and return on investment for health systems, insurers, patients, and society. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70034.

The authors evaluate the efficacy and safety of emerging therapeutic strategies for CKD management, including sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1RA), finerenone, sacubitril/valsartan, and potassium binders. Read the full text manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70014.

Drs. Adrian Wong, Sandra Kane-Gill, and Alexandre Chan discuss their ACCP Committee work with associate editor, Dr. Alan Zillich. The committees' work resulted in two papers describing the current and future role of AI in clinical pharmacy practice, research, and scholarship. Read the full-text manuscripts: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70004 and https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70003.

Dr. Michael Rybak hosts authors of the 2025 Update on Antibiotic Safety in Pregnancy. Listen to what you can expect from this comprehensive review of changes and new drugs, since 2015. Access full text of the manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70010

Learn about the decades of effort put in by Drs. Leslie Hendeles and Randy Hatton to get the ineffective oral formulation of phenylephrine removed from OTC products. Dr. Kelly Goode provides perspective on the importance of the community clinical pharmacist for optimizing patient care and understanding. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.2080.

The goal is to reduce high-risk medication use to mitigate HF exacerbations and improve outcomes. Author Joshua Jacobs shares his teams work on determining the prevalence of prescription medication use that can exacerbate heart failure among US adults with heart failure. Read the full text OPEN ACCESS manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4648.

In this episode of the JACCP Podcast, hosts Robbie Parker and Stuart T. Haines discuss the impact of pharmacogenomics on formulary decision-making with Dr. Jacob Brown and Dr. Larisa Cavallari. The conversation highlights how genetic testing should influence a Pharmacy & Therapeutics (P&T) committee's work to optimize medication safety and effectiveness. The guests discuss the variability in pharmacogenomic adoption across institutions, barriers such as clinician education, cost, and reimbursement challenges, and the importance of physician-pharmacist collaboration. They also described gene-drug pairs where the evidence is compelling, like clopidogrel, fluoropyrimidines and codeine, demonstrating the value of pharmacogenetic-guided prescribing. Finally, they offer guidance for smaller institutions looking to implement pharmacogenomic strategies, emphasizing a stepwise approach and leveraging available resources. Read The impact of pharmacogenomics on a pharmacy and therapeutic committee's formulary system management: An opinion of the pharmacokinetics/pharmacodynamics/pharmacogenomics practice and Research Network for the American College of Clinical Pharmacy in JACCP.

A comprehensive overview of transthyretin amyloidosis, its treatment, barriers to treatment, and future challenges to be aware of with authors, Drs. Erika L. Hellenbart and Robert J. DiDomenico. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4639.

This episode of the JACCP podcast, hosted by Editor-in-Chief Stuart T. Haines, explores the themed issue on "Clinical Pharmacy Practice, Education, and Advocacy in the Management of Diabetes," with guest editors Dr. Christine Schumacher and Dr. Jennifer Clements. They discuss key advancements in diabetes care, including continuous glucose monitoring (CGM), compounded GLP-1 receptor agonists, glucagon access, and the evolving role of pharmacists in hospital, post-transplant, and outpatient settings. The episode emphasizes education, collaborative care, and emerging research while addressing challenges such as medication access.

An overview of current and emerging PCSK9-directed therapies; their efficacy, safety, and role in clinical practice. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4635.

Learn about the safety, efficacy, and place in therapy of this new agent. Access the full-text open access manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4629.

Interviews with Leaders in Clinical Pharmacy: Stuart T. Haines, Pharm.D., FCCP, FAPhA, FASHP, BCACP, BCPS, incoming JACCP Editor-in-Chief

Incorporate this specific data on the efficacy and safety of SGLT2Is into the larger body of literature on SGLT2Is. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4620.

Over 380K vancomycin treatment courses were used to evaluate the predictive performance of various vancomycin PK models across diverse age and BMI categories. Learn how to apply these findings to your patient. Full text of the Open Access manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4613.

Explore the basis for and controversy surrounding the US Food and Drug Administration requiring a Risk Evaluation and Mitigation Strategy (REMS) for mifepristone. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.2034.

Interprofessional education (IPE) is a pivotal force shaping the future of health care delivery. This podcast highlights aspects of and approaches to IPE within pharmacy education. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.2011

Explore the concept power and how it should influence how you read primary literature and design your own research. Open access to the full manuscript: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.4605

Learn how and why the Advancing Pharmacist Payment Parity Workgroup tackled the task of systematically comparing different states' approaches to pharmacist reimbursement by examining affected payers, billable services, and other pertinent details. Check out the paper for model characteristics for states considering the enhancement or development of legislation and regulations to ensure equitable payment mechanisms for pharmacist services: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.2008

Improve patient safety by learning strategies to overcome data challenges. Earn patient/medication safety CPE for listening to this podcast: https://www.accp.com/store/product.aspx?pc=ps24. Access full-text of the manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.2002

Improve pediatric patient safety by learning strategies to incorporate measures into clinical workflow. Earn patient/medication safety CPE for listening to this podcast: https://www.accp.com/store/product.aspx?pc=ps24. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jac5.1975

An overview of the development process and recommendations made for the use of long-acting antiretrovirals for the treatment and prevention of HIV-1. Full text available Open Access at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2922

Reflections from a large healthcare system not affiliated with a college of pharmacy on building a robust pharmacy research program. Full text manuscript available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1957.

Learn about how this ACCP Commentary demystifies the interpretation of pharmacogenomic test results and empowers pharmacists to apply genetic data alongside other clinical variables to optimize medication-related outcomes for their patients. Read the full Open Access manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1958.

A discussion with the lead authors of the new consensus recommendations on the use of novel antiretrovirals in persons with HIV who are heavily treatment-experienced and/or have multidrug-resistant HIV-1. Full text of the manuscript is available Open Access at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2914

All the internal medicine pharmacists are doing it, but what are they doing and is it working? Learn about this group's impact on antimicrobial stewardship. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1926.

Dr. Ellen Uppuluri provides perspective on anticoagulation management in postpartum women based on a case report and the research surrounding it. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2917.

Discover the tools you need to plan, fund, and implement a stewardship program based on this group's experience with anticoagulation stewardship. Full text of the OPEN ACCESS manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1936

Updates on the strategies, regimens and duration of the treatment of pulmonary drug-resistant tuberculosis. Full text manuscript available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2909

Advice for program directors seeking diversification within their residency program and guidance for non-US candidates seeking residency training. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1902

Learn about the development, plans for use, and continual evolution of a consensus-based set of outcomes and measures to standardize psychiatric pharmacy practice and research. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1917

Explore how to mitigate, monitor for, and establish clinically relevant thresholds of clozapine-associated inflammation. Access full text of the manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2887

Fascinating research out of the University of Michigan on L-carnitine and its relation to kidney function and outcomes in patients with septic shock. OPEN ACCESS to the full text manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2882

Learn about the extended pharmacist involvement in discharge transitions of care that led to a reduction in readmission rates. Open Access full text available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1887

Interviews with Leaders in Clinical Pharmacy: Leigh Ann Ross, Pharm.D., FCCP, FAPhA, FASHP, FNAP

Gain an understanding of the barriers and facilitators to warfarin patient self management in US. Full text available open access at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1879.

How did the COVID-19 pandemic affect faculty research and scholarship output in the short- and long-term? Should tenure and promotion benchmarks be adjusted? Full text available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1857

An update to the 2014 paper published in Pharmacotherapy, these standards of practice for clinical pharmacists define for the public, healthcare professionals, and policymakers what they can and should expect of clinical pharmacists. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1873

Which triazoles warrant therapeutic drug monitoring and when and how? This paper and podcast from the Society of Infectious Diseases Pharmacists describes the pharmacokinetic principles and pharmacodynamic targets of commonly used triazole antifungals. It provides the rationale for utility of TDM within each agent. Access the paper and supplements at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2850

It's been a long time since we've talked about theophylline. Dr. Paul Boylan will bring you up to date with this discussion about the ACCP Pulmonary Practice and Research Network's scoping review. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2843

Discussion of this systematic review will provide the critical care pharmacist with action steps for both practice and research related to management of pain, agitation, and delerium in mechanically ventilated adults. Full text of the manuscript: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1778

A look into the development and potential impact of the consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics. Lead authors, Lisa Hong and Marc Scheetz, share their insight. Full text of the open access manuscript: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2842

Dr. Brent Reed defines and discusses the threats to pharmacist well-being, and then proposes the initial steps for organizations to progress toward a solution. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1831

What are the roles, responsibilities, & challenges for clinical pharmacists when it comes to patient use of medical cannabis? Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1820.

A framework for discussing SSRI/SNRI tolerability with patients and their families and a description of the pharmacologic basis, course, and predictors of adverse events. Full text of the manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2767.

Insight on the necessary careful selection of patients with HFmrEF/HFpEF to those who are most likely to benefit from mineralocorticoid receptor antagonists. You can read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.2801.

What is required to assure all pharmacy graduates are “team-ready” clinicians? by Lucinda L. Maine, Ph.D., American Association of Colleges of Pharmacy; and Peter Vlasses, Pharm.D., D.Sc. (Hon.), FCCP, Accreditation Council for Pharmacy Education. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1038. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.

Unrealized potential and unrecognized value: Community-based pharmacy practice is reinventing itself—Join the movement by Melissa A. Somma McGivney, Pharm.D., FCCP, University of Pittsburgh; David D. Pope, Pharm.D., STRAND Clinical Technologies; and Troy Trygstad, Pharm.D., MBA, Ph.D., CPESN USA. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1147. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.

Clinical pharmacy practice in community pharmacies: A frontier with promise? by Jerry L. Bauman, Pharm.D., FCCP, University of Illinois Chicago and JACCP; and Henri R. Manasse, Jr., Ph.D., Sc.D. (Hon.), University of Illinois Chicago. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1138. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.

The endurance of medication overload: Rethinking the medication review process by James P. McCormack, Pharm.D., University of British Columbia; Shannon Brownlee, M.Sc., Lown Institute; Judith Garber, MPP, Lown Institute; and John W. Devlin, Pharm.D., FCCP, Northeastern University. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1150. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.

Roles of the clinical pharmacist during the COVID-19 pandemic by Alan E. Gross, Pharm.D.; University of Illinois Chicago and Conan MacDougall, Pharm.D., MAS; University of California San Francisco. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1231. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.

Hero clinical pharmacists and the COVID-19 pandemic: Overworked and overlooked by Jerry L. Bauman, Pharm.D., FCCP; University of Illinois Chicago and JACCP. Download the editorial at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.1246. View the full Opinions in JACCP Virtual Issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2574-9870.editorial.