Optimize Human Performance and Unleash Your Body's Total Horsepower! My name is Hunter Williams and I study how to optimize health to improve human performance. In my podcast, I dive deep into advanced health, wellness, fitness, and biohacking protocols to improve mental performance!
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I delve into the intricate relationship between testosterone therapy and mental health in both men and women. Drawing from extensive research and personal experience, I discuss how low testosterone levels can affect mood, energy, and cognitive functions, leading to issues like depression and anxiety. While testosterone therapy is not a cure-all, it can significantly alleviate certain mental health symptoms by optimizing hormone levels. I also address common misconceptions about testosterone therapy, such as the myth of 'roid rage,' and emphasize the need for a comprehensive approach to mental health that includes physical, emotional, psychological, and spiritual components. Additionally, I touch upon the importance of monitoring testosterone levels as a potential factor in mental health issues and offer insights into the impact of testosterone on cognitive improvement and mood stability, especially in hypogonadal individuals.
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I break down one of the most confusing topics in the entire peptide world — the difference between GHRHs (growth hormone–releasing hormones) and GHRPs (growth hormone–releasing peptides). I know a lot of people get tripped up by this, especially with so many companies selling blends that mix multiple GH peptides together. So I wanted to simplify it and show you exactly how these compounds work, what makes them different, and how to use them intelligently to get the best results.I'll walk you through how each class — GHRHs like CJC-1295 and Tesamorelin, and GHRPs like Ipamorelin and GHRP-6 — activates unique pathways in the body. You'll learn why stacking them correctly can amplify growth hormone release far beyond what either can do alone, and why combining the wrong ones is often redundant or even counterproductive.Whether you're brand new to peptides or have been experimenting for years, this episode will give you a clear framework for how to structure your peptide stack for anti-aging, better recovery, improved sleep, and optimized body composition. I'll also share my personal experience, what I've seen work best for clients, and how to avoid the common mistakes people make when using growth hormone–based peptides.If you've ever wondered how to pair CJC with Ipamorelin, when Tesamorelin makes sense, or what the real differences are between these compounds, this episode will give you all the answers — straight from my experience and research in the field.
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I dive deep into what I believe could be the most powerful synergy in the entire world of longevity and metabolic optimization — the combination of SGLT2 inhibitors (like Jardiance and Farxiga) with GLP-1 agonists (like Retatrutide, Tirzepatide, and Semaglutide).These medications were originally created for diabetics, but what we're learning now is that they may be rewriting the entire playbook on healthspan and lifespan extension. I break down the research showing how SGLT2 inhibitors not only lower blood glucose but also improve cardiovascular health, protect the kidneys, reduce inflammation, and even clear senescent cells — all while mimicking the effects of caloric restriction and fasting.Then, I explain how pairing them with a GLP-1 creates a metabolic symphony unlike anything else we've ever seen. Together, they reduce insulin resistance, improve energy metabolism, and activate the same longevity pathways linked to caloric restriction, AMPK activation, and mitochondrial renewal.If you care about living longer, staying leaner, and protecting every organ system in your body, this episode is a must-listen. I share what I've seen personally, what's happening in clinical data, and why I believe the GLP-1 + SGLT2 combo could end up being one of the greatest discoveries in modern medicine for both health and performance.
Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I dive deep into one of my all-time favorite immune-support peptides — Thymosin Alpha 1 (TA-1).As we head into cold and flu season, I wanted to do a full recap and update on why TA-1 is something I always keep in my own stack. It's one of those foundational peptides that a lot of people overlook once they move on to “sexier” compounds, but the truth is — few things strengthen the immune system, fight inflammation, and restore balance like this one does.I'll walk you through:What Thymosin Alpha 1 actually is and how it was discoveredHow it works in the body to activate T-cells, natural killer cells, and the innate immune systemIts antiviral, anti-tumor, and anti-inflammatory effects backed by global clinical studiesWhy it's FDA-designated for certain cancers and used in over 35 countries for immune-related diseasesThe real-world dosing strategies I use for immune maintenance, illness prevention, and recoveryHow TA-1 synergizes with glutathione and other immune peptidesAnd why it's an absolute must-have during stressful periods, travel, or any time your system feels run-downI also share some of the newer data around TA-1's role in cancer therapy, viral infections, and immune modulation — and why it continues to be one of the safest, most versatile peptides out there.If you're someone who wants to stay strong, resilient, and protected year-round without relying on the usual over-the-counter stuff, this episode is for you.
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I dive deep into one of the most important concepts for the future of health optimization — Peptide Replacement Therapy (PRT). Just like we replace hormones as we age, it's time to start replacing the endogenous peptides that naturally decline over time and are critical to maintaining energy, muscle, immunity, and longevity.I walk through 14 naturally occurring peptides — like IGF-1, Thymosin Alpha 1, TB-500, KPV, MOTS-C, Humanin, SS-31, Glutathione, Epitalon, Kisspeptin, Oxytocin, GHK-Cu, and others — explaining what they do, how they decline with age, and how we can safely and effectively use peptide analogs to restore youthful balance and optimize the aging process.If you're already optimizing hormones, this is the next frontier in extending healthspan and performance — Peptide Replacement Therapy.
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video I break down pregnenolone for men on testosterone therapy and share when it helps, when it does nothing, and when it can backfire. We cover the steroidogenesis pathway so you can see where pregnenolone sits as the mother hormone. I explain how TRT suppresses LH and FSH and why that can lower testicular production of upstream steroids even if adrenal output is unchanged. I walk through pregnenolone's role as a neurosteroid, how it converts to allopregnanolone, and why that often improves sleep quality, stress tolerance, and mood via GABA modulation. I also outline signs of low pregnenolone, summarize what the clinical literature suggests about cognition and anxiety, and give simple dosing guardrails I use personally and with clients. As always none of this is medical advice. Use it to have a smarter conversation with your clinician.
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I break down one of the most misunderstood topics in the GLP-1 world — microdosing Retatrutide. There's a lot of debate online about whether you should take Retatrutide once per week or split it into multiple smaller injections. Today, I'm going deep into the science, pharmacokinetics, and real-world experience behind both approaches so you can decide what's right for you.I cover how microdosing affects appetite, energy, side effects, and results, and why it might be the better approach for long-term metabolic optimization. You'll also learn how this compares to traditional weekly dosing and why both methods can work — depending on your goals.
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Creatine is one of the simplest, most proven tools for strength, brain energy, and healthy aging. In this deep dive, I explain what creatine is, how it actually powers ATP, what the human data shows for performance, cognition, recovery, and longevity, how to dose it (with or without a loading phase), common myths and side effects, and why newer forms like “creGAAtine” might help you saturate muscle and brain with less water bloat. If you've asked me for my baseline supplement stack, this is where I start.
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Injectable Glutathione: 2025 Update & Comprehensive GuideHey everyone, it's Hunter Williams here! In today's video, I bring you my 2025 update on glutathione, particularly injectable glutathione. I've used it for years and continue to be amazed by its benefits. This video expands on my previous content with newer clinical evidence and informed recommendations. We'll discuss its role in mitigating the effects of mitochondrial peptides, combating environmental stressors, and maintaining liver health. I'll delve into the bioavailability challenges of oral glutathione versus injectables, specific use cases like liver disease, male fertility, and even chemotherapy support. Plus, I'll share how to properly administer it, monitor its effects, and my personal insights on how it enhances energy, immune function, and overall well-being. Don't miss out on this detailed and informative guide—perfect for anyone into peptide research or looking to optimize their health! As always, check the links in the description, and don't forget to join my email list for updates. Thanks for your continuous support. Let's dive in!00:00 Introduction and Video Overview02:39 What is Glutathione?03:47 Bioavailability and Delivery Methods06:06 Mechanisms of Action and Benefits08:41 Clinical Applications and Case Studies25:27 Dosing Guidelines and Best Practices28:48 Conclusion and Final Thoughts
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Timestamps00:00 Introduction and Video Overview00:14 Oxytocin and Its Connection to Fat Loss01:16 Scientific Data and Research on Oxytocin02:30 Mechanisms of Oxytocin in Fat Loss04:23 Oxytocin's Effects on Appetite and Metabolism05:29 Comparing Oxytocin with Other Weight Loss Aids10:37 Direct Actions of Oxytocin on Fat Cells11:59 Animal and Human Studies on Oxytocin19:26 Oxytocin Usage Protocols24:33 Potential Side Effects and Safety26:56 Conclusion and Final ThoughtsJoin me, Hunter Williams, as I delve into the fascinating connection between oxytocin—the 'love hormone'—and its surprising benefits for fat loss. Discover the scientific data and practical insights that show how this peptide hormone can enhance muscle preservation, improve metabolism, and reduce cravings for high-fat foods. Learn the optimal ways to use oxytocin, including dosing protocols and the synergy with diet and exercise. Don't forget to stay connected by joining my email list for updates on new videos and content. Let's dive in and explore how oxytocin can support your fitness and wellness journey!
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Timestamps00:00 Introduction and Q&A Overview01:39 First Question: CJC 1295 Dosage02:20 Retatrutide with HCG Monotherapy03:04 Peptides for Relaxation and PTSD03:49 Peptides for Migraines04:22 Combining GLP-1 and Tesamorelin04:51 Workout Timing and Peptide Injections06:08 Dealing with GLP-1 Fatigue07:54 GLP-1 for Autoimmune Diseases09:22 Peptides for Cold, Flu, and COVID-1909:55 Peptides for Energy and Overall Health10:39 Testing Peptides Separately vs. Blends13:16 Metformin and Biomarker Testing14:18 Body Recomposition and Peptides15:07 Peptides for Tendinitis and Pain Management16:18 Muscle Building Peptides17:25 Metformin and Protein Synthesis18:07 Thoughts on SARMs19:16 Enclomiphene for Testosterone Production20:25 Injectable Bioregulators22:48 Peptides for Heart Health23:30 Peptides for Lung Issues25:40 Peptides for Hair Growth30:12 Shipping Peptides in Summer Heat31:08 Testosterone for Women31:34 Bio Regulators for All Ages31:53 Metformin and Jardiance: A Powerful Combo32:22 Peptides for Histamine and Inflammation32:54 Reconstituting Peptides: Tips and Tricks34:31 Stacking Peptides: Safety and Recommendations34:56 Comparing Metformin and ATX 30436:02 Combining Peptides for Appetite and Weight Management36:44 Titrating Off Tirzepatide38:33 Understanding Blood Sugar and Insulin40:37 Testosterone Therapy and Hair Loss41:22 Peptides for Joint Pain and Recovery42:19 Peptides for Lung Health42:53 Peptides for Fat Loss in Athletes43:42 Synthetic vs. Natural BioRegulators44:21 Peptides and Gene Mutations45:53 Testosterone Levels in Women46:26 GLP Drugs for Weight Loss47:02 Peptides for Perimenopausal Women47:47 Stacking Tirzepatide and Retatrutide48:29 Daily Timing of Peptides and Supplements50:39 Combining Peptides in One Syringe51:19 Peptides for Bladder Infections51:54 Muscle Growth with Retatrutide53:47 Peptides for Older Adults54:40 Hormone Imbalance in Women Over 5555:13 Peptides for Pets56:43 Supplements with TRT57:27 Evaluating Sermorelin58:55 Dealing with Peptide-Induced Cramping01:00:06 Final Thoughts and Appreciation
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/00:00 Introduction and Video Overview00:20 Personal Experience with SS 3101:43 Scientific Basis and Human Trials03:25 Mechanisms of SS 3107:37 Clinical Applications and Benefits14:46 Dosing Guidelines and Safety21:21 Emerging Applications and Future Potential26:51 Conclusion and Final ThoughtsIn this comprehensive deep dive into SS-31, I'll be sharing my personal experience with this powerful mitochondrial peptide, its scientific mechanisms, clinical applications, dosing guidelines, and the outstanding benefits observed in various human trials. Whether you're looking to enhance your energy levels, improve athletic performance, or support your cardiovascular and cognitive health, SS-31 offers promising solutions. Don't miss out on this essential biohacking tool!
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/I break down the human data on HGH (human growth hormone) for anti-aging and performance—what actually improves, what doesn't, and where it clearly helps (injury recovery and true GH deficiency). I also cover side effects, dosing philosophy (“replacement, not enhancement”), and how to think about HGH in a longevity stack as you age.Timestamps0:00 - Intro, goal of the video and who this is for2:10 - What HGH is and age-related decline (somatotropin refresher)3:28 - The Rudman 1990 study and “turning back the clock” claims4:26 - 1994–1996 trials: lean mass up, strength/endurance unchanged5:00 - 2002 Blackman RCT + meta-analysis: +2 kg lean, −2 kg fat7:00 - Side effects: edema, joint pain, carpal tunnel, insulin resistance (dose-dependent)8:38 - Athletic performance evidence: banned in sport, but does it help?10:06 - WADA/Stanford findings: sprint bump, no strength/endurance gains12:20 - Injury & healing overview: why HGH could help tissue repair12:36 - Burn-healing data: faster closure and shorter stays (with hyperglycemia risk)13:48 - Fracture healing: tibial fracture RCT, closed vs. open outcomes15:28 - ACL surgery study: better knee extensor strength without bigger muscles17:02 - Adult GH deficiency (AGHD): signs, causes, quality-of-life impact18:48 - Early AGHD trials (1989–1990): composition, VO₂, well-being improvements19:40 - 2000s–today: cardio risk markers, aerobic capacity, long-term outcomes20:34 - Who benefits most: AGHD/older adults vs healthy/athletes25:08 - Replacement vs enhancement: practical dosing philosophy26:00 - Final verdict: where HGH fits in a longevity stack27:14 - New studio, channel update, and closing thoughts
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In today's video I unpack amlexanox—an old anti-inflammatory/allergy drug with surprising metabolic effects. I share my first encounter with it in the research-chem world, what I noticed subjectively, and then dive into mechanisms (IKKε/TBK1 inhibition, catecholamine resensitization, beige fat), rodent data, the Phase 2 human trial (150 mg/day), safety, dosing, who seems to respond best, and how I'm stacking it inside Bio Ignite. If your goal is fat loss with stubborn adipose inflammation, this is worth understanding.0:00 - Welcome + what today's video covers0:28 - How I first found “AM Lox” browsing catalogs1:06 - Cycling off SLU-PP-332 and first personal trial1:40 - Noticing dryness/ab definition; early under-dosing2:12 - 2025 “sugar diet” + hunting for FGF21 boosters2:40 - Finding data that amlexanox increases FGF213:02 - Literature dosage (100–150 mg) vs my early dose3:38 - Why I think it's a useful fat-loss rotation tool4:24 - Channel/hosting update + where to find my videos5:08 - Slides start: what amlexanox is/was used for6:00 - Core mechanism: IKKε/TBK1 → PDE3B → cAMP resistance7:16 - IL-6→STAT3 hepatic signaling + beigeing via FGF218:30 - Big-picture benefits: inflammation, insulin sensitivity, glycemia10:32 - Human data: Phase 2 trial (150 mg/day x 12 weeks)11:10 - Modest/variable weight change; who improved most12:37 - Practical takeaways: glycemia, liver fat, insulin sensitivity14:12 - Dosing in practice (50 mg caps, TID = 150 mg/day)15:12 - Responder phenotype: high adipose inflammation16:00 - Who benefits most + variability at similar body fat17:56 - Study roll-up and mechanism recap18:52 - Final thoughts, use-cases, and product note (Bio Ignite)19:54 - Thank you + where to grab the peptide cheat sheetWhat You'll LearnWhy amlexanox can “release the brakes” on fat-burning by inhibiting IKKε/TBK1 and restoring cAMP/catecholamine responsiveness.How it raises IL-6 transiently in adipose, activates STAT3 in the liver, suppresses gluconeogenesis, and increases FGF21 to promote beige fat programs.The mouse vs. human gap: robust fat loss in mice; in humans, clearer improvements in A1c, fructosamine, liver fat, insulin sensitivity—especially when adipose inflammation is high.Dosing used in the Phase 2 trial: 50 mg TID (total 150 mg/day) for 12 weeks.Safety snapshot: no serious AEs attributed to amlexanox in metabolic trials; most common was a transient rash.Timestamps (exact to the transcript)What you'll learn
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this 2025 refresh I walk through why GHK-Cu remains one of the most versatile, well-tolerated peptides for systemic repair and cosmetic wins. I cover mechanisms (copper delivery + gene modulation), data across tissues (skin, bone, liver, lung, gut, nerves), and performance/brain angles (sleep loss resilience, anxiolysis, analgesia). I also talk realistic use cases, stacking concepts, and where the research is heading—plus how I'm rebuilding after my original channel was deleted. If this helped, drop a comment and make sure you're on my email list so we can stay connected no matter what platforms do next.0:00 - Intro, channel update & why I'm revisiting GHK-Cu3:09 - What is GHK-Cu? Discovery, decline with age & why it still matters4:46 - Core mechanisms: copper delivery + gene-expression “reset”9:50 - Wound healing fundamentals (closure, granulation, angiogenesis)11:06 - Systemic healing even under steroids (cortisone models)13:00 - Organ regeneration: liver “youth,” COPD gene signature, gut lining14:18 - Ulcerative colitis 2025 study: cytokines down, barrier up17:10 - Skin rejuvenation: collagen, firmness, pigmentation18:20 - Hair growth: anagen extension, minoxidil-level results22:08 - Practical stacks, safety notes & key takeaways
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I break down ATX-304 (also known as OS-01 or OS-03) — a powerful small molecule AMPK activator being studied for fat loss, metabolic health, and longevity. If you've heard ATX-304 described as “exercise in a capsule,” you'll see why after going through the research, mechanisms, human trials, and potential applications.I also share how ATX-304 works differently than GLP-1s, why it preserves muscle while supporting fat loss, and what the future may hold for this compound in anti-aging medicine.
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/0:00 - Intro: why I'm covering Testagen0:30 - The low-T epidemic and TRT context1:12 - Why I'm excited about Testagen vs HCG2:00 - What I'll cover today (what it does, dosing, use cases)2:40 - What Testagen is (KEDG bioregulator peptide)3:12 - Mechanisms and “does this help women?” note4:00 - Core effects: endocrine support + epigenetic action5:00 - Target tissues: pituitary, thyroid, testes, bone marrow6:00 - Vascular/erectile benefits; “calibrating” the HPT axis6:30 - Fertility use case + my personal plan7:16 - Manufacturer indications; sexual function improvements8:12 - Case study: semen parameters quadrupled on Testolutin8:58 - Thyroid support, TBI/central hypo considerations9:58 - Anti-aging & immune modulation overview10:20 - Human evidence: oral Testolutin study (TT, LH/FSH ↑)11:02 - Human evidence: IM Testagen (2.5 mg x 10 days) results11:48 - 2022 combo study (4-peptide stack; free T ↑ ~54%)13:08 - Animal data: pituitary-independent thyroid restoration14:08 - Cell data: nuclear entry, histone/DNA binding14:34 - Outcomes summary: testosterone, LH/FSH, libido15:02 - Testagen vs TRT; stacking with Epitalon/Epithalamin16:01 - Safety profile: “no significant side effects” noted16:56 - Dosing protocol I recommend (2 mg/day, 10–60 days)17:24 - Full male-health stack ideas (Testagen + others)17:40 - Big-picture takeaway: who benefits most18:10 - Real-world reports, call for comments, and thanksI break down Testagen (a KEDG bioregulator) as a legit pathway to support testicular function, HPT axis “calibration,” and fertility—without typical TRT downsides. I walk through how it works at the epigenetic level (nuclear entry, histone/DNA interaction), human and animal evidence (oral Testolutin and injectable Testagen), thyroid and immune benefits, erectile/vascular support, and what I've seen in early adult men with low T. I also share my fertility plan, practical dosing (2 mg/day; 10–60 days), and how I'd pair Testagen with peptides like Epitalon, Libidon, Glandokort, and Superfort for broader rejuvenation. If you've used Testagen, drop your experience—wins or misses—so we can help the community learn what's working.
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Link to Study: https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1616693/fullGet My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Study Link: http://biorxiv.org/content/10.1101/2025.04.17.649402v1.full.pdfGet My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
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