Podcasts about apob

Modern anxiety isn't just emotional. It's chemical — and it's being triggered and sustained by the way we're living, consuming, and overstimulating ourselves every single day. In this powerful, personal episode, Elizabeth pulls back the curtain on what's really happening when we feel anxious for "no reason" — and shares the neurochemical truth about dopamine, oxytocin, cortisol, and inflammation. If you're constantly in your head, overwhelmed, overstimulated, or one step away from panic — this conversation will shift everything. You'll also hear the exact strategy Elizabeth is using to reclaim peace and presence in her everyday life — without deleting her business, becoming a monk, or pretending life isn't loud and full.

In this episode, Ben Azadi reveals the real reason arteries clog and it's not age, genetics, or cholesterol. The true driver of heart disease is chronic inflammation and metabolic dysfunction. Ben breaks down five science-backed drinks proven in human studies to reduce arterial plaque, lower inflammation, improve insulin sensitivity, boost nitric oxide, and support long-term cardiovascular health. You'll learn how simple ingredients like pomegranate juice, high-quality coffee, raw cacao, apple cider vinegar, and turmeric can dramatically improve markers like ApoB, CRP, triglycerides, fasting insulin, and blood pressure. Ben also explains how to rotate these drinks for maximum benefit, which options are best for keto or diabetes, and how quickly you can expect to see results in your lab work. This episode empowers you with practical, natural tools your doctor likely never mentioned, helping you take control of your metabolic and heart health starting today. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat   - https://bit.ly/3L6xMo0 

In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don't fit—within a thoughtful, individualized approach to cardiovascular risk.From there, we explore integrative strategies for managing elevated cholesterol and why, for many patients, lifestyle, metabolic health, and inflammation-targeted interventions may be more effective than medications alone.In this episode, we discuss:Why cholesterol is biologically essential and not inherently pathologicalThe limitations of relying on LDL alone to assess cardiovascular riskHow inflammation, insulin resistance, genetics, hormones, and lifestyle influence lipid metabolismWhen elevated cholesterol truly signals disease—and when it may reflect a compensatory or adaptive responseThe role of advanced markers such as ApoB, Lp(a), hsCRP and CAC scoresWhy risk stratification—not fear-based medicine—should guide clinical decision-makingWhat statins can (and cannot do) and we break down the concerns people have with themWhy integrative approaches (nutrition, exercise, herbal options and mind-body medicine) truly treat the root cause of diseaseThis episode is for clinicians, patients, and anyone looking to move beyond simplistic cholesterol narratives toward a more nuanced, evidence-based understanding of cardiovascular health.

Welcome to part two of our Best of 2025 series - the moments that changed how our listeners think about their health and what they do on a day-to-day basis. In this episode, we delve into simple questions with profound impact. Is it safe to experiment with your own health? Does cheese really cause bad dreams? Why do some breakfasts leave you tired and hungry, while others don't?  If you're looking for practical, science-led ideas you can take into the year ahead, this episode brings together the insights listeners found most useful, surprising, and worth returning to. Unwrap the truth about your food

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter tackles a wide-ranging set of listener questions spanning lifespan interventions, exercise, cardiovascular risk reduction, time-restricted eating, blood pressure management, hormone therapy, diagnostics, and more. Peter reveals the single most important lever for extending healthspan and lifespan, and explains how he motivates midlife patients using the Centenarian Decathlon framework. He discusses the importance of addressing high apoB and cholesterol even in metabolically healthy individuals with calcium scores of zero, how to manage high blood pressure, and how to accurately evaluate metabolic health beyond HbA1c. Additional topics include time-restricted eating, practical considerations around ultra-processed foods, nuanced approaches to HRT for women and TRT for men, and why early and expanded screening for chronic disease—colonoscopy, PSA, coronary imaging, low-dose CT—can be lifesaving. He also offers insights into treating prediabetes, crafting exercise programs for those short on time, and safely incorporating high-intensity training in older adults. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #78 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Introducing a wide-ranging AMA: practical perspectives on lifespan interventions, metabolic health, diet, hormones, diagnostics, and more [2:45]; Why exercise is the most powerful single intervention for lifespan and healthspan [4:15]; How Peter motivates midlife patients to prioritize exercise [6:00]; Why lifespan and healthspan should not be treated as competing priorities and how choosing sustainable interventions benefits both [9:30]; Why high apoB deserves treatment even in a metabolically healthy patient with a CAC score of zero [14:00]; Managing hypertension: ideal targets for blood pressure, lifestyle levers, and why early pharmacology matters [18:15]; Assessing metabolic health beyond HbA1c: fasting insulin, triglycerides, lactate, zone 2, and more [23:30]; How to avoid common self-sabotaging patterns by choosing sustainable habits over extreme health interventions [26:00]; Time-restricted eating: minimal effect beyond calorie control, implications for protein intake, and practical considerations for implementing it [28:00]; Ultra-processed foods: definitions, real-world risks, and practical guidelines for smarter consumption [30:30]; How women should prepare for menopause and think about hormone replacement therapy: early planning, symptom awareness, and guidance on HRT [36:45]; Testosterone replacement for aging men: indications, benefits, and safe clinical management [39:45]; Why Peter recommends earlier and more aggressive screening tests than guidelines suggest: colonoscopies, coronary imaging, PSA, Lp(a), and low-dose CT scans, and more [43:30]; Full-body MRI screening: benefits, limitations, potential false positives, and the importance of physician oversight [47:15]; Prediabetes: individualized treatment strategies using tailored combinations of nutrition, sleep, and training interventions [51:00]; Time-efficient training plans for people with only 30 minutes per day to exercise [53:00]; How to safely introduce high-intensity exercise for older adults [55:00]; Timed dead hangs and ripping phone books: a playful look at Peter's early attempts to impress his wife [57:15]; Peter's carve out: The Four Kings documentary about a golden era of boxing [1:01:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. We're joined by Dr. Laurence Sperling to break down what's new in ASCVD risk assessment and prevention. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Intro Case 1 from Kashlak  Risk assessment framework ApoB and Non-HDL cholesterol Lipoprotein(a) and its importance The PREVENT risk score and its implications Statins and other lipid lowering therapies The role of diet and lifestyle in lipid management Case 2 from Kashlak Familial Hypercholesterolemia diagnosis and management Key takeaways Outro Credits Producer, Writer, Shownotes, Infographic, and Cover art: Ben Furman, MPH  Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Leah Witt, MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Laurence Sperling, MD  Disclosures Dr. Sperling reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. Sponsor: Bucksbaum-Siegler Institute If you want to learn more about what the Bucksbaum-Siegler Institute is doing and to nominate someone for the Clinical Excellence Award—you can check them out today. Visit bucksbauminstitute.uchicago.edu. Sponsor: Grammarly  Sign up for FREE and experience how Grammarly can elevate your professional writing from start to finish. Visit Grammarly.com/podcast.  Sponsor: Continuing Education Company Use promo code Curb30 to get 30% off all online courses and webcast. Visit CMEmeeting.org/curbsiders to learn more. Sponsor: Freed Use code: CURB50 to get $50 off your first month when you subscribe!

Dr. Carlos Hernández nos comparte 5 claves para mantener un corazón saludable y prevenir un infarto. Descubre cómo funciona el corazón y qué factores pueden llevarlo a enfermarse, así como las estrategias más efectivas para protegerlo y mantenerlo en óptimas condiciones.El Dr. Carlos Hernández desmitifica creencias comunes, como la idea de que el cardio es una pérdida de tiempo, y nos ofrece consejos prácticos para prevenir enfermedades cardiovasculares. Si estás interesado en cuidar tu corazón y mejorar tu salud cardiovascular, este episodio es una guía esencial.Show Notes(00:00) Intro: ¿El deporte extremo daña tu corazón? (02:39) Medicina Convencional vs. Medicina Funcional (El iceberg) (05:45) La epidemia silenciosa: Por qué los infartos empiezan a los 20 años (08:41) Anatomía 101: Cómo funciona la bomba cardíaca y el sistema vascular (13:02) Genética vs. Hábitos: ¿Estás condenado por tu herencia familiar? (16:22) Cómo saber si tienes un corazón sano (Señales visibles y funcionales) (19:50) La métrica reina: El VO2 Max y por qué la "normalidad" es estar enfermo (23:21) Los exámenes que tu médico NO te pide (ApoB, Lipoproteína A y Calcio Coronario) (32:01 ) ¿A qué edad deberías empezar a medirte? (La prevención real) (36:21) El peligro de la Lipoproteína (a) y el tabaco (39:11) La VERDAD sobre el Colesterol LDL: Mitos y realidades (43:00) Entendiendo la ApoB: La analogía de los "Barcos" y la carga (48:30) El Endotelio: La barrera que realmente protege tus arterias (53:01) ¿Insulina, Triglicéridos o Colesterol? Qué priorizar (56:22) Muerte súbita en atletas: ¿Por qué gente fit muere haciendo ejercicio? (59:15) El Estrés Crónico: El asesino invisible de emprendedores y creadores (1:05:03) ROMPEMITOS: Por qué la Obesidad y la Hipertensión son mecanismos de defensa (1:13:05) Cómo fortalecer el corazón: La dosis perfecta de ejercicio (1:18:30) Cardio vs. Pesas: El mix de longevidad para llegar bien a los 80 (1:25:22) Nutrición para el corazón: Qué comer y qué evitar (1:28:40) Suplementación clave: Omega 3 y Aceite de Oliva (1:31:21) Ritmos Circadianos: Dormir y vivir como humanos (1:35:01) Biohacking: Qué es la VFC (HRV) y cómo medir tu estrés (1:44:21) Cómo mejorar tu VO2 Max (Cardio aburrido + HIIT) (1:49:12) El mensaje final: De qué se arrepiente la gente antes de morir- Recibe 5% de descuento en tu suscripción de los mejores suplementos utilizando el código CREADORES en https://belevels.com/- Recibe acceso gratuito a mi lista de los 100 libros que transformarán tu vida aquí: https://www.creadores.co/newsletter- Únete a nuestra Escuela de Creadores, un programa de 12 semanas para transformar tu cuerpo, mente y negocios: https://creadores.co/escuela- Invierte en bienes raíces en EE. UU. con nosotros en Creadores Capital y genera retornos promedio del 20% anuales. Aplica aquí: https://www.creadorescapital.com/Invitado- Instagram: https://www.instagram.com/dr.carloshernandez1/- Sitio Web: https://www.doctorcarloshernandezmd.com/Creadores- Facebook: https://www.facebook.com/creadorespodcast- Instagram: https://www.instagram.com/creadorespodcast- Instagram: https://www.instagram.com/chelozegarra- TikTok: https://www.tiktok.com/@marcelozegarrac- Twitter: https://twitter.com/chelozegarrac- Email: https://www.creadores.co/contacto#CreadoresPodcast #CuidadoDelCorazón #SaludCardiaca #PrevenciónDeInfartos #ConsejosDeSalud

I am honored to have Dr. Tom Dayspring join me again today for another AMA session. He and I have done eight podcasts before, and this is a continuation of our last Ask Me Anything episode.  Dr Dayspring is an esteemed expert on internal medicine and clinical lipidology. He is likely one of the most influential worldwide lipid experts, so I am thrilled to have him back with me to dive into various topics related to listener questions, including the impact of hormone replacement therapy on lipid changes, methods of administration, and why bioidentical hormone replacement therapy is preferable for managing both menopausal symptoms and lipid health. We discuss medications, including PCSK9 inhibitors and GLP-1s, as well as intermittent fasting, lipids, and cardiovascular disease risk. We also examine how heart disease develops gradually, over time, the impact of stress and lifestyle, and Dr. Dayspring shares the labs he recommends beyond traditional lipids, ApoB, and LpA. In our discussion, Dr. Dayspring noted that he was not in a position to speak about GLP-1 therapies or microdosing. Since I received many questions from listeners on those topics, I will host a future solo AMA to address some of their concerns. Today's conversation with Dr. Tom Dayspring is truly invaluable, and I trust you will walk away with valuable insights you can share with your healthcare providers. We created a PDF - cynthiathurlow.com/lipids -  specifically for listeners that outlines key labs to discuss with your providers and questions to ask them to help you advocate for your own health and your family members' health. IN THIS EPISODE, YOU WILL LEARN: Why being physically fit does not always eliminate the risk of heart problems arising How ApoB and cholesterol contribute to heart disease over decades Why the early testing of risk factors is essential How chronic stress increases the risk of heart disease  How high cortisol affects insulin sensitivity and glucose regulation How stress impacts endothelial and nitric oxide function The link between low Omega-3 levels and heart problems How insulin resistance degrades heart health How high homocysteine levels can impair endothelial function and contribute to cardiovascular problems Connect with Cynthia Thurlow   Follow on⁠ X⁠,⁠ Instagram⁠ &⁠ LinkedIn⁠ Check out Cynthia's⁠ website⁠ Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community ⁠(The Midlife Pause/Cynthia Thurlow⁠)⁠ ⁠ Cynthia's⁠ Menopause Gut Book⁠ is on presale now! Cynthia's⁠ Intermittent Fasting Transformation⁠ Book ⁠The Midlife Pause supplement line⁠ Connect with Dr. Thomas Dayspring On X (@DrLipid) On LinkedIn

"What's good for the heart is good for the brain."  Can better cholesterol management in midlife actually lower your patient's risk of Alzheimer's disease? In this episode, I'm joined by returning guest Josh Wageman, PhD, PA-C, a clinical lipid specialist who studied cholesterol disturbances in Alzheimer's disease.  Together, we unpack how cholesterol, APOB, APOE4, insulin resistance, and statins intersect with Alzheimer's disease and cognitive decline, and what clinicians can do now to protect brain health long before symptoms appear. Plus, a peek at emerging therapies (including GLP-1 receptor agonists and lipid-centric approaches) and how a metabolic lens is reshaping future Alzheimer's treatment.Resources Mentioned:Josh's New Book117 | What's the Best Diet to Lower Cholesterol?111 | HDL = Good, LDL = Bad? It's Not That Simple.80 | The MIND Diet: What To Eat For Brain HealthAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

In this episode of The Kirk Miller Podcast, Kirk sits down with Daniel Salewski—Founder and Director of Elite Vita—to explore the science and strategy behind extending not just lifespan, but health span: the years you live with vitality, clarity and peak performance. Daniel specialises in advanced DNA analysis, biomarker interpretation, and NAD-driven cellular optimisation, working with high performers who want to understand their bodies at a far deeper level than traditional healthcare ever allows. This conversation breaks down the real levers of longevity—rooted in data, not trends. In this episode, you'll learn: Why DNA testing + blood work is the new foundation of personalised health The difference between being in range and being optimal—and why most people settle for the former What NAD actually is, why levels drop with age, and how it impacts energy, recovery and brain performance The truth behind biological age vs chronological age—and how people are now reversing it How genetic variants affect nutrient absorption, inflammation, hormones, mood and more Why Vitamin D, APOB, CRP and other biomarkers predict disease risk long before symptoms show The order Daniel recommends for anyone serious about longevity: test first, then intervene Daniel also shares how Elite Vita is pioneering a more personalised approach to healthcare—moving away from guesswork and towards precision-led protocols tailored to each individual's biology. If you're a business leader, entrepreneur or high performer who wants more energy, better health and a longer runway to operate at your best, this episode will give you clarity on what to do next—and what to ignore. For more information on what was discussed in this episode head to https://kirkmiller.co.uk/programme/ The Kirk Miller Podcast is the show for business leaders and peak performers to get into the best physical and mental shape of their lives and unleash from within confidence they never thought possible.

Neste vídeo, detalhamos as recomendações da nova Diretriz Brasileira de Dislipidemias sobre a dosagem de Apolipoproteína B (ApoB). Entenda em quais cenários clínicos — como na hipertrigliceridemia e na síndrome metabólica — esse marcador se torna superior ao LDL-c para uma estratificação de risco cardiovascular mais precisa.Endocrinologia descomplicada para médicos e residentes. Aqui você encontra conteúdos sobre atualização médica, casos clínicos e preparação para provas de título.

Blutwerte sind der Gesundheitskompass des Körpers. Jonas Köller erklärt, welche Werte wirklich zählen, warum das „große Blutbild“ überschätzt wird und wie du gefährliche Mängel früh erkennst. Von LDL über HbA1c bis Vitamin D: So liest du deinen Körper wie ein offenes Buch.

Heart attacks in people with “normal” cholesterol are not rare outliers. They're the warning flare that our entire playbook is broken. In this episode of Medical Disruptors, I sit down with interventional cardiologist-turned-functional cardiologist Dr. Sanjay Bhojraj to unpack what happens when you do everything “right” on paper… and still end up in the ER with a heart attack. We get into advanced lipid testing (ApoB, Lp(a), and small dense LDL) and how different LDL particle patterns can drive very different levels of plaque risk. We also break down how standard stress tests miss the very plaques that actually rupture, and why CTA and smarter labs are finally giving us a way to see real cardiovascular risk. Your labs, your lifestyle, your environment, and your nervous system all matter—and you deserve a plan that reflects that. Hit play and start upgrading how you think about your heart. Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters [00:00:00] Introductions and background [00:04:31] Eight-heart-attack weekend [00:06:53] Discovering functional medicine [00:27:38] Advanced cholesterol labs [00:49:34] Programs and next steps Guest Links: FB: @doctorsanjaymd IG: @doctorsanjaymd YT: @doctorsanjaymd Website: www.lagunamedicne.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Ben Azadi breaks down five science-backed metabolic drinks that naturally reduce arterial plaque, boost nitric oxide, lower inflammation, and support metabolic health — without medications or side effects. You'll learn: • Why arterial inflammation — not cholesterol — is the real silent killer• How pomegranate juice reversed arterial plaque by 30% in human studies• The surprising cardiovascular benefits of high-quality coffee with butter, olive oil, and salt• Why raw cacao improves arterial flexibility by up to 400% (Harvard study)• How apple cider vinegar and cinnamon lower fasting glucose, HbA1c, and triglycerides• The anti-inflammatory power of turmeric + black pepper and how it calms the arteries Ben also explains:• Which drink is best for diabetics• How to rotate the drinks weekly for maximum benefit• What markers to test before and after 30 days to measure progress (ApoB, CRP, fasting insulin, triglycerides, HDL, CAC score, and more) Plus, he shares a free guide revealing the five vegetables silently inflaming your gut and slowing your metabolism — and what to eat instead. A simple daily cup could dramatically upgrade your cardiovascular and metabolic health. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat - https://bit.ly/48CIprn

Ready to go beyond standard cholesterol panels and track what actually matters? Get your comprehensive performance bloodwork analysis at  witsandweights.com/bloodwork (code VITALITY20 for 20% off)—What if your blood work is missing the markers that truly predict long-term cardiovascular health? Can you build muscle, lose fat, and stay strong after 40 without risking your heart? And which biomarkers, hormones, and peptides actually move the needle for longevity and performance?I bring on Integrative Medicine & Cardiology Physician Dr. Abid Husain into the conversation, and we get into the evidence behind cardiovascular health for lifters, especially if you're focused on body recomp, strength training, weight loss, nutrition, and fitness. We cover the labs most people never get, how inflammation and metabolism shape heart health, and why tracking APOB, CRP, and oxidized LDL matters far more than total cholesterol. We also break down hormone health, HRT safety, muscle building over 40, and the peptides that actually support recovery and longevity.If you care about lifting weights, performance, and living longer with evidence-based fitness, this one gives you a clear roadmap. Tune in to learn more.Today, you'll learn all about:0:00 – Defining cardiovascular health3:40 – Mechanical vs biochemical heart health7:42 – Obesity, genetics, and heart disease12:10 – Key biomarkers to track18:55 – Inflammation patterns and risk23:20 – Cholesterol, genetics, and LDL nuance28:40 – Hormone health and HRT safety35:20 – Peptides for recovery and performance49:55 – Calcium scoring vs CCTA imaging*Episode resources:*Website: boulderlongevity.com Dr. Abid Husain's Instagram: @dr_abidhusain Boulder Longevity Institute's Instagram: @boulderlongevityinstitute LinkedIn: linkedin.com/in/abid-husain-md-facc-abaarm-00874419 YouTube: @boulderlongevityinstitute Facebook: @BoulderLongevityInstitute Support the show

“Cardiologist Dr. Jack Wolfson reveals the true root causes of heart disease — and why it's far more preventable than you've been told.”Dr. Brooke Stubbs sits down with cardiologist Dr. Jack Wolfson to uncover the real causes of heart disease beyond cholesterol. They discuss toxins, inflammation, gut health, mindset, lifestyle, and the advanced labs that actually matter. Dr. Wolfson also shares why he left conventional cardiology and why he believes heart disease is 100% preventable. A must-listen for anyone ready to take control of their cardiovascular health naturally.⭐ What You'll Learn• Why Dr. Wolfson left the hospital system to pursue preventative, natural care• How toxins, environment, and daily habits trigger heart disease• Why nutrition & organic living matter more than pharmaceuticals• What labs actually predict cardiovascular risk (ApoB, oxidized LDL, inflammation markers, intracellular nutrients)• How gut permeability (“leaky gut”) connects to plaque and inflammation• Circadian rhythm, sleep, sunlight & nervous system health• The truth about stress, relationships, trauma & heart attacks• Why Wolfson says 100% of heart disease is preventable• Parenting, homeschooling, and raising healthy families

Most people assume that normal cholesterol means a healthy heart, but that isn't always the case...     On today's show, we dive into why Apolipoprotein B (ApoB) is one of the most important yet overlooked markers for assessing true cardiovascular risk.     You'll learn why ApoB can reveal hidden plaque formation even when LDL appears normal, the ideal range to aim for, and why inflammation and metabolic health often matter more than total cholesterol alone.     We'll also explore the deeper factors that influence heart health, including insulin resistance, thyroid function, gut permeability, hormonal changes, diet, stress, and sleep.      Join me on today's Cabral Concept 3581 to discover what your cholesterol panel may be missing and how to take a more accurate, proactive approach to protecting your heart.     Enjoy the show!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3581 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

A long-term Framingham Heart Study analysis shows that regular physical activity beginning in midlife and continuing into older age significantly lowers the risk of dementia, including Alzheimer disease, with the most active individuals experiencing roughly 40–45% risk reduction. A phase 3 trial of the first oral PCSK9 inhibitor, enlicitide, demonstrated substantial LDL-C and apoB reductions in patients with heterozygous familial hypercholesterolemia already on statins, offering a well-tolerated oral option that helps most patients reach guideline targets. Finally, a large U.S. cohort study revealed persistent under-treatment of chronic hepatitis B—especially among women and non-Asian racial groups—highlighting the need for standardized assessment and timely antiviral therapy to close these gaps.

Dr. Erin Faules speaks with Dr. Damon Forbes about Lp(a), a genetically influenced lipoprotein linked to cardiovascular disease risk. They discuss how Lp(a) differs from LDL, its role in plaque and clotting, and why a one-time test can help clarify long-term risk. The conversation covers who to screen and when, interpreting Lp(a) alongside apoB and metabolic health, evidence-based ways to lower overall cardiovascular risk, and emerging Lp(a)-lowering therapies

“I think everyone should have Lp(a) measured.”  - Dr. Ann Marie Navar   Key Resources to Go Deeper:  - Dr. Ann Marie Navar  - Lp(a)  - Get a Free Test to Check Your Lp(a) Level   - Previous episode with Dr. Navar about ApoB  About This Episode:  Listen to this replay of an important discussion about Lipoprotein(a), or Lp(a), a critical but often overlooked marker for cardiovascular health. In this episode, host Barbara Hannah Grufferman takes a deep dive with medical expert Dr. Ann Marie Navar from UT Southwestern Medical Center about why this single test could be vital for understanding your heart disease risk, especially if you have a family history of early cardiovascular disease.  Key Topics Covered:  - What Lipoprotein(a) is and how it differs from standard cholesterol measurements  - Why Lp(a) testing is particularly important for certain individuals  - The genetic nature of Lp(a) and its implications for family health  - Current treatment options and promising new therapies on the horizon  - Practical steps for discussing Lp(a) testing with your healthcare provider  Key Takeaways:  - Lp(a) is a distinct type of cholesterol particle not captured in routine lipid panels  - High Lp(a) levels significantly increase risk of heart disease and stroke  - Lp(a) levels are primarily determined by genetics and remain stable throughout life  - Current guidelines recommend universal Lp(a) testing for adults  - New treatments specifically targeting high Lp(a) levels are expected by 2026  - Managing other risk factors can help offset the risk of elevated Lp(a)  - Coronary artery calcium scoring can provide additional risk assessment  Learn More About Dr. Ann Marie Navar  Dr. Navar is a preventive cardiologist and epidemiologist at UT Southwestern Medical Center whose research focuses on cardiovascular disease prevention, risk prediction, and clinical decision-making. She is a leading expert in advanced lipid testing and cardiovascular risk assessment. This is Dr. Navar's second appearance on AGE BETTER, following her previous discussion about the ApoB test, which was one of the most down-loaded episodes in 2024.   Connect With Barbara:  Have ideas for future episodes? We'd love to hear from you!  - Email: agebetterpodcast@gmail.com  - Connect on Instagram HERE  Note: This episode is for informational purposes only and does not constitute medical advice. Please consult with your healthcare provider about your specific situation. Learn more about your ad choices. Visit megaphone.fm/adchoices

“VO2 max is the best predictor of lifespan,” says Peter Attia, M.D. Peter Attia, M.D., physician, founder of Early Medical, and expert in the applied science of longevity, joins us today to break down the key levers for extending both lifespan and healthspan—from how to train for a higher VO2 max to the biomarkers that truly predict long-term health. - The most powerful habit for longevity (~6:15) - VO2 max (~8:55) - How to increase your VO2 max (~10:08) - Heart rate vs. perceived exertion (~12:35) - Attia's strength training routine (~15:20) - 2 exercises Attia stopped doing (17:00) - Diminishing returns in terms of exercise (~19:55) - His take on wearables (~21:25) - Cardiovascular disease markers (~23:38) - Lowering ApoB (~25:35) - Pharmaceutical interventions for LDL & ApoB (~27:50) - Neuroinflammation markers (~37:25) - Perspectives on statins (~40:45) - The role of nutrition (~42:50) - Potential benefits of GLP-1s (~45:00) - Peptides (~47:50) - The power of exercise (~51:00) Referenced in the episode:  - Follow Attia on Instagram (@peterattiamd) - Listen to his podcast, The Peter Attia Drive  - Check out his website (https://peterattiamd.com/)  - Pick up his book, Outlive: The Science of Art & Longevity  - Take his class on MasterClass (https://www.masterclass.com/series/science-for-a-longer-better-life) - Watch the trailer for his class on MasterClass (youtube.com/watch?v=f_Mz095swls&feature=youtu.be)   We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Jila Senemar is a board-certified OB-GYN in Miami who's integrating longevity medicine with menopause care. After nearly two decades in traditional practice, part of her work is catching women in their 30s and 40s before chronic disease develops.We discuss why your standard annual labs are missing the markers that actually predict heart disease and diabetes, how to finally break free from the cardio-only mentality that's keeping you from building muscle, and why eating more protein feels impossible when you've been trained to restrict food your entire life. Dr. Senemar reveals the advanced testing she runs on every patient and explains why most women are being managed reactively instead of proactively.We cover transitioning out of insurance medicine to actually spend time with patients, why strength training won't make you bulky, and when peptides and longevity treatments fit into your health plan. Plus, we talk about what it means to optimize your health span, not just your lifespan.Highlights:The critical biomarkers your doctor isn't checking (ApoB, Lp(a), fasting insulin, inflammatory markers).Why perimenopause accelerates your risk for heart disease and metabolic problems.How to shift from endless cardio to building muscle that protects your bones and metabolism.The real reason getting enough protein feels so hard and why it matters.When peptides, NAD, and supplements belong in your health plan.Starting health optimization in your 30s instead of waiting for disease in your 50s.This show has grown over nearly two years thanks to viewers and listeners like you. While menopause and sexual health have become more mainstream, too many women still aren't getting the help or education they need. I'm working to change that. If you found this episode helpful, please subscribe to the show and leave a review on Apple Podcasts. Get in Touch with Dr. Senemar:WebsiteInstagramPodcastGet in Touch with Me: WebsiteInstagramYoutubeSubstack

Heart disease is still the leading cause of death, yet most people never learn about the tests that actually reveal their true risk. In this episode of the Medical Disruptor, I explain why your genetics are not your destiny, why traditional cholesterol panels often miss the full picture, and how modern testing can show what is really happening inside your arteries. My goal in this episode is to help you understand your true risk, build a prevention-focused care team, and take back control with information that is rooted in evidence, not fear. If you've ever been told your labs are “normal” but still want deeper answers, this episode gives you the modern roadmap for protecting your heart. Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters: 00:00 Intro 00:43 Why traditional heart-disease testing is incomplete 03:12 Genetics vs environment: what really drives risk 06:55 Cholesterol myths & particle number explained 13:28 ApoB, Lp(a), LDL-P: the tests that matter 19:45 Inflammation, insulin resistance & metabolic fire 25:30 Gut–heart connection: what the microbiome reveals 29:55 How to build your heart-health team 33:22 Four habits that lower risk by up to 80% 36:44 Final takeaway: prevention you can start today Learn more about your ad choices. Visit megaphone.fm/adchoices

I'm excited to share a new AMA episode with you today, dedicated to risk factors specific to women. In this AMA session, I dive into the lifestyle factors that influence lipids, exploring the latest research and discussing Lp(a) and ApoB. Rather than answering your individual questions, I have woven them into the overall outline to create a cohesive and informative conversation. IN THIS EPISODE, YOU WILL LEARN: How women's lifestyle choices directly affect their lipid profiles How knowing if you're a hyper absorber or hyper producer of cholesterol will change your treatment strategy What the Boston Heart Cholesterol Balance test will reveal about your body's ability to handle cholesterol The best treatments for hyper absorbers, and the best treatments for hyper producers How hard plaque differs from soft plaque, and why that matters for women's heart health How the new AI-assisted Clearly scan provides a more complete cardiovascular risk picture than a standard calcium score How chronic stress and elevated cortisol fuel insulin resistance and inflammation, and damage blood vessel linings The benefits of Mediterranean-style eating for improving lipid balance, vasomotor symptoms, and overall metabolic health The importance of managing trauma, stress, and emotional health in midlife How my “n=1” experiment with Zetia and micro-dosed GLP-1s significantly improved my ApoB and inflammation markers Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Resources:  Dietary natural products as emerging lipoprotein(a)-lowering agents The Effects of Menopause Hormone Therapy on Lipid Profile in Postmenopausal Women: A Systematic Review and Meta-Analysis An Update on Lipoprotein(a): The Latest on Testing, Treatment, and Guideline Recommendations

The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong? In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression. We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression. You'll learn:

I used to think of fiber as just “good for digestion,” but it turns out this single nutrient can lower cholesterol as powerfully as a statin—and do so much more for your brain, gut, and longevity. In this minisode of The Neuro Experience, I sit down with Dr. Rupy Aujla — NHS doctor, author, and founder of The Doctor's Kitchen — to break down the science behind fiber and why it's one of the most underrated tools for preventing heart disease and inflammation. This episode features highlights from our full conversation, which premiered August 5th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=Jay-Sg2sg6s Connect with Dr. Rupy Aujla: Website: The Doctor's Kitchen Instagram: @doctors_kitchen Books: The Doctor's Kitchen & Eat to Beat Illness *** Topics discussed: 00:18 – The TikTok “fiber maxxing” trend explained 00:42 – How to transition from low-fiber to high-fiber safely 01:02 – How fiber binds cholesterol and removes it from the body 01:26 – Feeding your gut microbes: the real reason fiber matters 02:10 – What short-chain fatty acids do for inflammation and longevity 03:00 – How fiber increases LDL receptor activity in the liver 03:42 – How 60 days of high-fiber eating lowers ApoB and LDL 04:03 – The “Portfolio Diet” that rivals statins 05:08 – The best fiber-rich foods: oats, barley, soy, nuts, seeds 06:14 – What to know about oats, glyphosate, and processing 07:16 – The perfect high-fiber breakfast recipe 07:53 – How food can match statin effects (and go beyond) 09:10 – The one daily change to reduce heart attack and stroke risk 09:26 – Dr. Rupy's B.B.G.S. formula for everyday health 10:13 – How fiber diversity transforms cholesterol and gut health *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

I recently had an ApoB test and am surprised that it isn't lower than it is.  Can you explain?I have an ascending thoracic aortic aneurysm.  How can I keep it from enlarging?Why are you against whole-body scans? Aren't they helpful?Can I take magnesium L-threonate while also taking magnesium glycinate?

The Real Truth About Cholesterol, Heart Disease & Cardiovascular Health SUMMARY What if your cholesterol isn't trying to kill you—it's trying to protect you? In this solo deep-dive, Coach Debbie Potts breaks down the outdated cholesterol myths and reveals the root-cause truth behind cardiovascular disease. Drawing from the work of Dave Feldman, Dr. Ben Bikman, Dr. Paul Mason, Ivor Cummins, and Dr. William Davis, Debbie explains why heart disease is an inflammatory, metabolic, and endothelial problem—not a cholesterol problem. Learn which markers truly predict risk, how to interpret your labs beyond LDL, the role of genetics and epigenetics, and what it really takes to reverse plaque and rebuild a resilient metabolism. If you're ready to move beyond fear and finally understand your cardiovascular health through the lens of functional, ancestral, and root-cause medicine, this episode is your roadmap. KEY TAKEAWAYS LDL isn't "bad"—oxidized, inflamed LDL in a damaged arterial wall is. Heart disease = terrain dysfunction: insulin resistance, oxidative stress, mitochondrial damage, and loss of nitric oxide. ApoB + inflammation predict risk far better than total cholesterol. Context matters: High LDL in a low-inflammation, insulin-sensitive body ≠ the same risk as in a high-inflammation body. Saturated fat isn't the enemy; oxidized seed oils and sugar are. You can't out-supplement poor habits. Sleep, stress regulation, circadian alignment, and daily movement build vascular resilience. Plaque can stabilize or regress when you heal the root causes. The WHOLESTIC Method™ integrates nutrition, movement, sleep, stress, digestion, hydration, and happiness to rebuild your health from the inside out. TESTS & TOOLS MENTIONED - talk to your provider! ApoB (< 80 mg/dL optimal) LDL-P (< 1,000 nmol/L) Triglyceride : HDL ratio (< 1) hs-CRP (< 0.5 mg/L) Lp(a) (< 30 mg/dL) Fasting Insulin / HOMA-IR (< 5 µIU/mL / < 1.0) Coronary Artery Calcium (CAC) Score (0 = clean) CCTA / Cleerly AI Analysis for plaque composition Carotid IMT, Omega-3 Index, Homocysteine, Vitamin D + K2

Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

Send us a textMost lab reports end with a shrug: “You're fine.” We think you deserve better than fine. This conversation is a practical guide to reading your blood work with confidence, using trends over time, and translating numbers into action you can stick with. Brent from Sage Healthspan joins us to unpack why “normal” ranges aren't the goal in a metabolically unwell population, how a closed-data AI can protect privacy while clarifying your results, and which overlooked biomarkers can change your prevention plan.We walk through the markers that move the needle. For cardiovascular risk, ApoB outperforms total cholesterol, while Lp(a) can reveal a genetic risk hidden in standard panels and point you toward a timely calcium score. Men should treat PSA as a low-friction lifesaver rather than an afterthought. Women deserve complete hormone panels, not piecemeal tests that miss the bigger picture. We also break down composite markers, ratios, and biological age as motivators—useful not as verdicts, but as guides to your next best step.The episode connects labs with real life. Sleep, training load, season, and environment all shape your biology. Wearables like Oura can inform when to push or pull back; vitamin D shifts with sunlight; fasting changes testosterone; and context matters as much as the number itself. We share how Sage ingests historical labs, normalizes units, explains biomarkers in plain English, and even drafts smart questions you can email to your doctor so every appointment counts. The aim is simple: lower friction, improve clarity, and build health agency that compounds over time.If you're ready to move from “okay” to optimal, tune in and learn how to centralize your data, fill panel gaps affordably, and make better daily choices backed by evidence. Subscribe, share with a friend who's ready to own their health, and leave a review to help more listeners find the show.Support the showLearn More at: www.Redefine-Fitness.com

Our guest, Hunter Ziesing shares his work with AI in assisting individuals in their quest for health and longevity.   Hunter spent the bulk of his career in investment banking focusing on the Healthcare, Consumer, and Technology areas. He was the founder of Charity of Choice, a non-profit focused on cancer research and health prevention. Early Overall Outcomes Biomarker Improvements A majority of patients showed significant movement in at least one critical biomarker (ApoB, VAT, bone density, VO2Max, HbA1c). ~80% improved at least one key biomarker. Common improvements included reductions in ApoB, decreases in visceral fat (VAT), and gains in lean mass/bone density. Major Findings from Diagnostics ~65% of patients had at least one significant finding from testing (e.g., early CAD on Cleerly, sleep apnea, insulin resistance, GI imbalances). These findings directly shaped interventions and escalations in care. Symptom Reversals ~30% experienced meaningful reversal of previously severe symptoms (e.g., hypertension control, prediabetes reversal, improved sleep apnea, reduction in chronic GI symptoms). Resources: ai.longevityhealth.me Our Sponsor: Haven Medical maker of the Cox 8 Table  

In this episode of Death Clock, Brent speaks with Dr. Nazish Sayed, a Stanford cardiologist and vascular biologist, to cut through the confusion about cholesterol, heart disease, and statins. Dr. Sayed breaks down what LDL, HDL, and ApoB really mean, why high cholesterol is more about your biology than your breakfast, and how inflammation and genetics drive plaque buildup long before symptoms appear. He explains how statins work and why their benefits far outweigh the risks for most people. It's an evidence-based exploration of one of medicine's most misunderstood topics. Hope you enjoy.

Send us a textCurious why coconut oil can raise LDL for some people yet still show up in diets that improve metabolic health, cognition, and body composition? We get clear on what coconut oil actually is—a family of saturated fats with a rare abundance of medium-chain triglycerides—and why MCTs create ketones that the brain and mitochondria can use even without fasting. Instead of stopping at cholesterol, we look at the fuller picture: insulin resistance, inflammation, triglycerides, and real-world outcomes that drive risk more than a single lab value.We dig into the differences between MCT oil, extra-virgin coconut oil, and refined coconut oil, and when each makes sense. We compare biomarkers to hard endpoints, explain why some populations with high coconut intake have low cardiovascular disease, and explore how diet context flips the script: in a high-sugar diet, lipids can look worse; in a lower-carb, whole-food pattern, markers of metabolic syndrome often improve even if LDL nudges up. Along the way, we share insights on cooking stability, oxidative stress, and the intriguing idea that latitude and season may influence how fats signal thermogenesis and photoprotection.You'll leave with practical takeaways you can use today: how to choose between MCTs and whole coconut oil, how to integrate them into a low-sugar, nutrient-dense diet, and which labs to track beyond LDL, like ApoB, triglyceride-to-HDL ratio, hs-CRP, and fasting insulin. If you've wondered whether coconut oil is a villain or a misunderstood ally, this conversation offers a grounded, outcome-focused way to decide what fits your body and your climate.Enjoyed the conversation? Follow the show, share it with a friend, and leave a quick review so more people can find it.www.thehealthedgepodcast.com

With Jean-Benoit Le Polain de Waroux, St-Jan Hospital, Brugge - Belgium, and Maarten De Smet, AZ Sint Jan, Brugge - Belgium.  Link to European Heart Journal paper Link to European Heart Journal editorial

With Allan Sniderman, McGill University, Montreal - Canada.  Link to European Heart Journal Editorial, by Allan Sniderman, Michael J. Pencina and George Thanassoulis Link to European Heart Journal Paper

In this episode of The Neuro Experience, I sit down with Dr. Kellyann Niotis—one of the first fellowship-trained preventive neurologists—to reveal how you can protect your brain long before symptoms of Alzheimer's or dementia appear. With Alzheimer's cases expected to triple by 2050, Dr. Niotis explains the difference between dementia types, the real role of genes like ApoE4, and why lifestyle choices may be more powerful than genetics. If you want actionable tools to lower your risk, strengthen your memory, and understand the future of preventive neurology, this conversation delivers science-backed strategies you can start applying today. About Dr. Kellyann Niotis: Dr. Kellyann Niotis is the first fellowship-trained preventive neurologist focused on reducing risk for Alzheimer's, Parkinson's, and Lewy Body Dementia. She launched the nation's first Alzheimer's Prevention Clinic at Weill Cornell and now leads early-detection and brain health research at the Institute for Neurodegenerative Diseases Florida. Her work appears in leading medical journals and has been featured by CNN. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode:TimelineHead to⁠ http://timeline.com/neuro⁠ to get started. BeamVisit ⁠http://shopbeam.com/TNE⁠ and use code TNE at checkout. Jones Road BeautyHead to ⁠http://Jonesroadbeauty.com⁠ and use code NEURO at checkout. After you purchase, they will ask you where you heard about them. PLEASE support our show and tell them our show sent you. NOCDHead to ⁠http://learn.nocd.com/NEURO⁠ and book a free 15 minute call to get started. Eko HealthGo to ⁠http:/ekohealth.com/NEURO ⁠ for up to $50 off, plus a free chest piece cover.  *** I'm Louisa Nicola — clinical neuroscientist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00 – Introduction 01:25 – Preventative neurology 02:23 – Dementia vs. Alzheimer's & Other Types of Dementia 04:08 – What Is Alzheimer's? 05:26 – Clinical Diagnosis: Imaging & Symptoms 07:07 – How Amyloid Disrupts Neural Communication 09:48 – Genetics vs. Lifestyle: Public Misunderstanding 12:02 – Role of Family History & Genetic Risk 14:04 – The ApoE4 Gene Explained15:07 – ApoE Variants 17:08 – ApoE4 and Lipid Transport in the Brain 18:35 – Immune Response & Infection Susceptibility 20:05 – Hormones: Key Role in Brain Health 21:08 – Genotypes & Risk Multipliers 23:01 – ApoE4 Not Always Deterministic: Population Studies 24:15 – Other Genetic Factors Beyond ApoE 25:13 – Biomarkers: Current Use & Limitations 27:13 – Risks of Self-Testing Biomarkers 28:45 – Why Two-Thirds of Patients Are Women 29:46 – Estrogen, Menopause & Neuroprotection 32:07 – Testosterone & Dementia Risk 35:01 – LDL, ApoB & Brain Health Debate 37:01 – Statins & Dementia: Myths vs. Evidence 39:08 – Fear & Misconceptions Around Cholesterol 41:09 – Lipoprotein(a) & Vascular Dementia Risk 44:39 – Brain Vasculature & Hypertension 49:15 – New Alzheimer's Drugs & Risks 55:32 – Why Rates Keep Rising (Lifestyle & Stress) 58:11 – Early Signs 01:00:23 – Tau Protein, Tangles & Neuronal Damage 01:05:49 – Keto vs. Mediterranean 01:07:14 – Personalization & Preference for Mediterranean Diet Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Girls Gone Wellness, we sit down with Dr. Matthew Nagra, one of the most respected naturopathic doctors focused in evidence-based nutrition. Known for cutting through the noise online and representing naturopathic medicine on some of the biggest stages, Dr. Nagra joins us to unpack some of the most controversial (and confusing) topics in nutrition.Here's what we get into:-Dr. Nagra's journey into naturopathic medicine and plant-based nutrition.-The truth about cholesterol, LDL, ApoB, eggs, and heart health.-Why seed oils aren't the villains the internet makes them out to be.-Plant-based proteins, soy, and whether fake meats are really better for you.-Red flags to watch for when spotting nutrition misinformation online.& so much more!Connect with Dr. Nagra below:Instagram is hereWebsite + booking link is hereFor more information & to join the Confident Clinician check it out here! Be sure to DM us on Instagram once you become a member for your special gift! Don't forget to follow us on Instagram @girlsgonewellnesspodcast for updates and more wellness tips. You can also subscribe to our Youtube Channel @Girlsgonewellnesspodcast to watch our episodes! Please subscribe to our podcast and leave a review—we truly appreciate your support. Let's embark on this journey to wellness together!DISCLAIMER: Nothing mentioned in this episode is medical advice and should not be taken as so. If you have any health concerns, please discuss these with your doctor or a licensed healthcare professional.

Dr. Hoffman continues his conversation with Jim LaValle, a clinical pharmacist and certified clinical nutritionist, detailing cholesterol's importance and its implications for cardiovascular health. 

September is Cholesterol Education Month. In this episode of Intelligent Medicine, Jim LaValle, a clinical pharmacist and certified clinical nutritionist, details cholesterol's importance and its implications for cardiovascular health. He delves into the nuances of cholesterol types, the historical shifts in perceptions of cholesterol, and how dietary and lifestyle factors influence cholesterol levels and cardiovascular risk. Jim provides expert insights into the roles of LDL and HDL cholesterol, the significance of cholesterol particle size, the impact of carbohydrates on cholesterol, and the benefits of aged garlic extract and other supplements. The conversation emphasizes the importance of comprehensive lipid testing, understanding individual risk factors, and integrating both lifestyle modifications and, when necessary, medications into cardiovascular preventive strategies. The episode concludes with a discussion on the role of health policies and the future of integrative health approaches.

If you or someone you love has had a heart attack, stent, bypass, or high calcium score, this episode is for you. In this episode, Dr. Robert Todd Hurst, MD, FACC, FASE breaks down the 10 most critical facts about coronary artery disease (CAD), from understanding the real risks, to reversing progression through precision treatment, to the surprising link between muscle mass, insulin resistance, and heart health. You'll learn what your doctor may not have told you, and how to protect your heart with the best available science and strategy.  Key Time Stamps:  00:45 – What coronary artery disease means & common fears after stents or bypass  01:37 – The #1 thing to know & the staggering stats behind heart disease in the U.S.  02:17 – Who is in the highest risk category   02:55 – Why >90% of heart disease is preventable (and how)  03:15 – Understanding insulin resistance and its role in artery disease  04:22 – What your LDL and ApoB numbers should really be  05:25 – Why “mildly elevated” blood pressure isn't actually mild  05:55 – The powerful link between fitness, muscle mass, and longevity  06:42– Why visceral fat matters more than BMI or total body fat  07:04 – How mental health, stress, and sleep impact your heart  07:20 – The danger of waiting: 25% of heart disease presents as sudden death  08:05 – Why can HealthspanMD prevent heart disease when the numbers are so bleak  09:33 – What the Heart Longevity Program at HealthspanMD includes  10:55 – The team, tools, and assessments that make this different  13:10 – The timeline for Heart Longevity Program at HealtspanMD  14:25 – Why now? What happens when people wait too long  This information is for educational purposes only and is not medical advice. Don't make any decisions about your medical treatment without first talking to your doctor.    Connect with HealthspanMD:  https://www.linkedin.com/company/healthspanmd/   https://www.facebook.com/healthspanmd   https://www.instagram.com/healthspanmd/  https://quiz.healthspanmd.com/    

When someone's LDL cholesterol hits 574 mg/dL, doctors typically expect the worst. But what if everything we think we know about cholesterol and heart disease risk is incomplete?In this episode, I sit down with researchers Nick Norwitz, Adrian Soto-Mota, and Dave Feldman to discuss their groundbreaking study on lean mass hyperresponders - a rare population who develop extremely high LDL cholesterol on ketogenic diets despite being lean, fit, and metabolically healthy. Their recent paper "Plaque Begets Plaque, ApoB Does Not" challenges conventional wisdom by showing that in this unique population, neither LDL cholesterol nor ApoB levels predicted plaque progression over one year of follow-up. Instead, existing plaque was the strongest predictor of future plaque growth. We explore the proposed lipid energy model that may explain why some people's cholesterol skyrockets on keto, discuss the limitations and implications of their findings, and examine what this means for personalized cardiovascular risk assessment. This conversation touches on fundamental questions about causality in medicine, the importance of studying outlier populations, and why a one-size-fits-all approach to cholesterol management may be missing crucial nuances.

FMF YouTube: https://www.youtube.com/@funmedFMI Center for Optimal HealthWebsite: fmioptimal.comInstagram: @fmioptimalFunctional Medicine of Idaho:Website: funmedidaho.comInstagram: @funmedidahoWe provide the highest quality supplements with responsible sourcing and the utmost commitment to purity funmedshop.com + more resources on IG: @funmedfoundations

Founder & CEO of Elevated Medical, Dr. Avinish Reddy, joins Matt today on this very special episode to discuss a comprehensive approach to longevity. One core theme presented is the profound interconnectedness of physical, mental, and cognitive well-being, essential for true health optimization. Dr. Reddy emphasizes the striking impact of social connection: isolation can increase early death risk by 50%, comparable to smoking. He believes fostering strong social bonds is a fundamental pillar of healthcare, akin to sleep's importance.The discussion highlights advanced diagnostics and actionable lifestyle strategies. Dr. Reddy advocates for precise cardiovascular risk assessment (apoB) and early metabolic dysfunction detection (fasting insulin/OGTT), with imaging (CT/CIMT) that visualizes arterial health proactively. As you will hear, prevention must begin decades before major health events, utilizing personalized data, and lifestyle is paramount - consistent movement, balanced nutrition, quality sleep, and stress management are vital for reversing conditions and fostering resilience.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.As a huge supporter of mission-driven companies, Matt recommends new partner Branch Basics. Their plant- and mineral-based ‘The Concentrate' is tough on kitchen grease yet gentle enough for baby toys, helping you create a toxin-free home. Get 15% off with code MattWalker at branchbasics.com/mattwalker.Craving more energy, better metabolism, and immunity? Discover Pique's Nandaka, a ceremonial cacao superfood blend for calm, sustained energy without the crash. Thanks to this wonderful podcast partner, you can now get 20% off for life at pique.com/mattwalker using code MattWalker.In a supplement industry where trust is critical, Matt uses podcast supporter Puori. Their protein powders are free from hormones, GMOs, and pesticides, with every single batch third-party tested for over 200 contaminants. For protein you can trust, save 20% at puori.com/mattwalker.As always, if you have thoughts or feedback you'd like to share, please reach out to Matt:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube: https://www.youtube.com/channel/UCA3FB1fOtY4Vd8yqLaUvolgConnect with Dr. Avinish Reddy:Elevated Medical: https://elevatedmedical.com/LinkedIn: https://www.linkedin.com/in/avinishreddy/Instagram: https://www.instagram.com/avinishreddymd/

Send us a textDr. Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease, and although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Dr. Josh Wageman is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!

We have the second episode in a series of conversations with Dr. Thomas Dayspring today.  The esteemed Dr. Dayspring is an expert on internal medicine and clinical lipidology. In this episode, we continue with our last conversation, diving into Lp(a) and the influences of gender, race, and menopause. We explain how estrogen is a PCSK9 inhibitor and explore the significance of brain health and risks for dementia. We tackle cholesterol synthesis and discuss the side effects of statins, clarifying who is most susceptible to their impact on the brain. We also examine the significance of the desmosterol biomarker, highlighting the level to aim for, especially when making decisions regarding cholesterol medications, and we answer one question from a listener.  You may want to listen to this insightful conversation with the renowned Dr. Dayspring more than once. He has graciously agreed to return and film additional episodes, where we will dive into more questions from listeners.  IN THIS EPISODE, YOU WILL LEARN: Why Lp(a) is like a wolf in sheep's clothing for many individuals How Lp(a) levels are higher in African Americans and women, especially after menopause  Dr. Dayspring highlights that Lp(a) particles are even more pro-inflammatory than LDL particles How PCSK9 inhibitors are the only drugs that significantly reduce Lp(a) Why do women have a higher risk of dementia than men? Dr. Dayspring explains ApoE as the key lipoprotein for brain cholesterol transport. How statins cross the blood-brain barrier to lower brain cholesterol Why desmosterol levels matter New therapies that can lower ApoB and Lp(a) Why imaging is essential for menopausal women with elevated ApoB and Lp(a) Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On X (@Drlipid) On LinkedIn Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations  Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?

I am deeply honored to reconnect with Dr. Thomas Dayspring, who joined me in 2024 for an immensely popular five-part series. Dr. Dayspring is certified in internal medicine and clinical lipidology. He is a distinguished fellow of both the American College of Physicians and the National Lipid Association.  Today, we have the first episode in a new series of conversations with Dr. Dayspring, in which he will share more of his perspective and answer more questions from listeners. In our discussion, we review the basics about cholesterol, triglycerides, and lipoproteins, exploring the factors that contribute to the development of cardiovascular disease, the significance of ApoB and Lp(a), and the risk factors for younger women. We also dive into the limitations of traditional allopathic medicines, and Dr. Dayspring shares his views on lipids, lipid changes in menopause, specific ways to address ApoB, some of the challenges associated with statin therapy, and more.  Dr. Dayspring brings a wealth of experience and expertise to this discussion, and you are sure to find this series as invaluable as the last. IN THIS EPISODE, YOU WILL LEARN: Dr. Dayspring revisits the differences between cholesterol, triglycerides, and lipoproteins What atherosclerosis is, and why it is concerning Dr. Dayspring explains the structure and function of lipoproteins The role of ApoB in lipoprotein particles and its significance in atherosclerosis Some of the risk factors for lipid abnormalities in younger women Lipid changes that occur as women transition from perimenopause to menopause  Dr. Dayspring shares his take on statin therapy Ways to address high ApoB Dr. Dayspring's suggested goals for ApoB therapy Connect with Cynthia Thurlow   Follow on ⁠X⁠, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia's ⁠website⁠ Submit your questions to ⁠support@cynthiathurlow.com⁠ Connect with Dr. Thomas Dayspring On⁠ X⁠ (@Drlipid) On⁠ LinkedIn⁠ ⁠Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations⁠  ⁠Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?⁠  

Send us a textOverview and alternative interpretation to the mainstream view on how dietary fat and cholesterol relate to cardiovascular disease.Episode Summary: Tucker Goodrich is an engineer by training who has become a prominent independent researcher and blogger on nutrition and metabolic health, focusing on the harms of seed oils and polyunsaturated fats.About the guest: Nick Jikomes and Tucker Goodrich explore atherosclerosis and heart disease, critiquing the standard model that blames high LDL cholesterol while highlighting how oxidized LDL—driven by dietary linoleic acid from seed oils—plays a key role in plaque formation and inflammation; they discuss historical shifts in heart disease rates, genetic factors like familial hypercholesterolemia, the limitations of animal studies, and why reducing seed oil intake could prevent issues more effectively than just lowering cholesterol.Discussion Points:Atherosclerosis involves plaque buildup in arteries, often leading to heart attacks, but plaques contain oxidized fats and cholesterol, not just native cholesterol.Dietary cholesterol has little impact on blood levels or heart disease in humans, unlike in rabbits used in many studies.High LDL may not be inherently bad; oxidized LDL from polyunsaturated fatty acids (PUFAs) like linoleic acid causes macrophages to overeat and form harmful foam cells.Familial hypercholesterolemia patients only show higher heart disease rates in modern, industrial diets high in seed oils, not historically.Populations like the Kitavans and Tsimané have high apoB but no heart disease on traditional diets low in industrial foods.Fried foods are oxidized seed oils, explaining why they're unhealthy despite omega-6 fats being labeled "heart-healthy."Omega-3 fats can displace omega-6 in cells, reducing oxidation risk.Reference Papers:Witztum & Steinberg (1991)Boren et al. (2022)Related episode:Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Trish: Hi Dr. Cabral - I'm a 55-year-old female working on lowering overall inflammation in my body. My CRP levels are (4.1), ApoB (118 nmol/L and Lipoprotein (A) (281 nmol/L) as you can see are high. Total Cholesterol 221 and Triglycerides are 70. I have a lot of stiffness with joint discomfort. I started taking 2 Proteolytic Enzymes upon waking. Then your DNS, D3/k2, Cell Boost, Inflamma Soothe, Collagen with GLP Tone System and some of your other products (eye and hair). I follow your Med diet. My pain and stiffness have improved ALOT in a matter of days. I'm going to retest my CRP and chol levels in 4 months. My question is how long can I take Proteolytic Enzymes and in your opinion am I taking the proper protocol for these issues? I'm retesting in 4 mos. Thank you in advance          Sheena: Hi Dr Cabral! Hope you and all of your health family are well. I'm a surgical Processor and on my feet all day. I've tried all kinds of compression socks but by the end of the day, after taking it off, my leg are soo itchy! I scratch it sometimes so bad it starts to bleed. I'm only wearing the average 15-20 mmHG so its not too tight. I'm curious if you have a recommendation for compression socks that wont causes itching but is effective? Thanks in advance for answering!      Christina: Stephen, I have listened on one of your podcasts about Rheumatoid Arthritis and detoxing. My mother is in her early 70s and her fingers are twisting. I am 48 and recently the base of my thumbs have started bothering me. My question is, what detox protocol should my mother start with to prevent further twisting of her fingers and what detox protocol should I do to prevent this from happening to me? I would love to do the heavy metals and organic acid tests, but unfortunately I live in NY. Would my functional medicine doctor be able to order them for me? I have had HELLP, HUS, DIC, Guillian Barre, and Pulminary Edema in my pregnancy at 21. My son was delivered with no issues! At this time, we learned that I have ITTP. I have had IBS issues. Thank you, Christina                      Ryan: Hi dr cabral, Im a 29 year old male who has addisons disease, chronic post nasal drip, food intolerance's and teeth grinding a stool test confirmed klebsiella pneumonie overgrowth and blastocystis hominis as well as some yeast and fungus with no Bifidobacteria and Lactobacillus detected, I recently started the cbo protocol with citricidal drops im 7 days in untill i came across one of your videos where you mentioned you should go for the parasite first should i stop the cbo protocol and start the para support protocol and then continue the cbo after or just continue the cbo protocol Thank you for your time wishing you all the best ryan.                                                                                                                                     Kay: Hi Dr. Cabral, I I love your podcasts and look forward to them every week. Anyway, I was wondering if you could please explain how a traumatic event could spur the onset of a "dis-ease" such as asthma. My daughter's asthma began shortly after her father and I were separated and he moved out of state. According to her pediatrician at the time, she was "more prone to having asthma because she also had eczema." This was 2 decades ago, and now she's 31 and we know more about autoimmune issues. Although she continues to carry an inhaler with her, she hardly needs to use it anymore. What would you recommend for a more root cause approach to someone with her condition? Thank you.                                  Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3466 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!