Podcasts about apob

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The Future of Everything presented by Stanford Engineering
The future of coronary heart disease

The Future of Everything presented by Stanford Engineering

Play Episode Listen Later Feb 27, 2026 36:26


Heart disease should be treated just like cancer, says guest Mike McConnell, an author and expert in preventive cardiology at Stanford: Detect and stage early, then treat aggressively. In his practice, McConnell focuses on using low-dose CT imaging for detecting early coronary artery disease. He also helped pioneer the use of AI to infer cardiovascular risk from retinal scans. Such non-invasive, consumer-friendly tools could expand prevention, personalize therapy, and cut heart attacks and strokes across the board, he says. “Everybody also deserves a proactive preventive cardiologist in their phone,” McConnell tells host Russ Altman of the latest approaches to heart disease on this episode of Stanford Engineering's The Future of Everything podcast. Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu. Episode Reference Links: Stanford Profile: Michael V. McConnell, MD, MSEE Connect With Us: Episode Transcripts >>> The Future of Everything Website Connect with Russ >>> Threads / Bluesky / Mastodon Connect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / Facebook Chapters: (00:00:00) Introduction Russ Altman introduces guest Michael McConnell, a professor of cardiology at Stanford University. (00:03:02) Reframing Heart Disease Why coronary disease should be approached the same as cancer. (00:05:46) Core Risk Factors The key drivers of cardiovascular disease, and life's essential eight. (00:07:18) Coronary Artery Calcium Scoring How low-dose CT scanning detects disease before symptoms develop. (00:08:57) The Limits of Stress Testing Why traditional stress tests often miss early coronary disease. (00:10:18) AI in Cardiac Imaging Using AI to identify hidden risks in routine chest scans. (00:11:30) Retinal Imaging How AI analysis of retinal blood vessels can predict heart disease risk. (00:14:55) Detecting Risk Before Symptoms Why retinal and vascular changes occur long before clinical signs appear. (00:15:58) Staging Coronary Disease Using calcium scores to stage coronary disease and personalize treatment. (00:19:36) Direct-to-Consumer Prevention The rise of mobile health records, wearable devices, and AI tools. (00:22:23) Opportunities & System Challenges Balancing accessibility, guideline-based care, and healthcare system capacity. (00:25:26) AI-Powered Health Record Analysis The potential of automated reviews to identify silent risk factors. (00:27:41) Physician Adoption & System Friction Barriers to integrating early detection tools into clinical practice. (00:30:12) Advances in Treatment Overview of current cholesterol therapies and plaque stabilization. (00:33:31) Future In a Minute Rapid-fire Q&A: prevention, implementation science, and future hopes. (00:35:38) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Health Matters
Diet and Your Heart: Can What You Eat Improve Your Numbers?

Health Matters

Play Episode Listen Later Feb 25, 2026 12:10


How much can what you eat really influence your heart health — and how quickly can you improve your blood pressure or cholesterol through diet? In this episode of Health Matters, host Courtney Allison sits down with cardiologist Dr. Sean Mendez of NewYork-Presbyterian Brooklyn Methodist Hospital to break down the real connection between food and cardiovascular wellbeing. They explore what your health numbers mean — from blood pressure ranges to LDL cholesterol, triglycerides, HDL, and the emerging marker ApoB — and how these values signal current or future risk. Dr. Mendez explains how dietary shifts can lower LDL cholesterol by 3 to 15 percent and reduce blood pressure by several points, even without medication. He also discusses salt sensitivity, the impact of saturated fats and processed foods, and why soluble fiber, healthy fats, and whole foods can play a powerful role in improving cholesterol. The conversation dives into the DASH diet and the Mediterranean diet, outlining how each works, what they emphasize, and the evidence behind their ability to reduce blood pressure and overall cardiovascular risk. Dr. Mendez offers practical tips for getting started and key lifestyle factors that are essential for heart health.  Whether you're hoping to lower your numbers, prevent future heart issues, or simply make more informed choices at the grocery store, this episode provides clear, accessible guidance on building a heart‑healthy way of eating. Chapters: 01:13 – What Do Heart Health Numbers Mean? 04:33 – How Quickly Diet Changes Improve Labs 10:59 – How to Start Changing Eating Habits Key Topics Covered What cholesterol, blood pressure, triglycerides, HDL, LDL, and ApoB measure How these numbers relate to cardiovascular disease risk Healthy ranges for blood pressure and cholesterol How diet can lower LDL cholesterol and blood pressure How quickly lab results change after modifying eating habits The role of salt sensitivity and saturated fats in heart health Foods that help lower LDL, including soluble fiber and healthy fats The DASH diet: its structure, purpose, and evidence for lowering blood pressure The Mediterranean diet: core foods, flexibility, and cardiovascular benefits Differences between DASH and Mediterranean diets Practical starting points for improving eating habits Benefits of tracking food intake and identifying patterns Easy, heart‑healthy food and snack swaps Why lifestyle factors like sleep, stress, exercise, and limiting alcohol matter Common misconceptions about eating for heart health Why heart‑healthy eating is beneficial at every age Takeaway Message Small, consistent changes to your diet and lifestyle can meaningfully improve your heart health — at any age. Understanding your numbers (like LDL, blood pressure, and ApoB) empowers you to make targeted choices, and evidence‑based eating patterns such as the DASH or Mediterranean diet can lower risk over time. Even if medications are part of your care, diet, sleep, exercise, and stress management remain essential tools for protecting your heart. Expert Guest Dr. Sean Mendez is a non-invasive cardiologist at New York Presbyterian Brooklyn-Methodist Hospital and an assistant professor of clinical medicine at Weill Cornell Medicine. His clinical interests include preventive cardiology, valvular heart disease, and cardiovascular imaging, including echocardiography, stress testing, and vascular imaging. In addition to seeing patients in his outpatient clinic, he provides inpatient care in the cardiac care unit, cardiac telemetry unit, and consultative cardiology service. Dr. Mendez is passionate about providing his patients with the highest-quality, comprehensive cardiovascular care. He addresses all aspects of health to prevent the development and progression of cardiovascular disease. Dr. Mendez, a native of Buffalo, New York, graduated magna cum laude from the University of Alabama with a bachelor's degree in both biology and mathematics. He attended medical school at the University at Buffalo, where he was inducted into the prestigious Alpha Omega Alpha Medical Society. Dr. Mendez then completed his residency in internal medicine at Massachusetts General Hospital/Harvard Medical School.  He then completed his fellowship in cardiology at the Mount Sinai Hospital, where he was chief fellow. For more health and wellness news, visit NewYork-Presbyterian's Health Matters website. 

Beyond Lifespan - Dein Fast-Track zu mehr Gesundheit
#103 ApoB statt LDL: Der bessere Cholesterin-Marker für dein Herzrisiko

Beyond Lifespan - Dein Fast-Track zu mehr Gesundheit

Play Episode Listen Later Feb 19, 2026 35:26 Transcription Available


ApoB ist für viele der präzisere Risikomarker als LDL-C: Nicht die Cholesterin-Masse, sondern die Anzahl der atherogenen Partikel treibt Atherosklerose. In dieser Folge klären wir, was ApoB genau misst, warum LDL-C täuschen kann (Discordanz!), welche Zielwerte sinnvoll sind und wie du praktisch vorgehst.

The Dr. Terri Show
87. Stop Blaming Eggs, THIS is The Real Cause of Heart Disease.

The Dr. Terri Show

Play Episode Listen Later Feb 17, 2026 19:23


"Since the 80s, we've been brainwashed to believe that eggs are bad for us, butter is bad for us, dairy is bad for us, red meat is bad for us. And it's just not true." If you've been told your cholesterol is "too high"... if you're on a statin drug and wondering if it's actually helping... if you care about preventing heart disease instead of just managing it... this episode is your wake-up call. It's Heart Health Month, and Dr. Terri is cutting through decades of misinformation to reveal what's REALLY driving cardiovascular disease — and it's not cholesterol. From the gut-heart connection to the six hormones that could save your life, this is the heart health conversation your doctor probably isn't having with you. Here's the truth: "The highest gross revenue producing drug in the history of drugs — billions of dollars — and since they've come out in the 80s, cardiovascular disease rates and death from cardiovascular disease have actually gotten worse, not better." WHAT YOU'LL DISCOVER: → Why heart disease is a disease of INFLAMMATION, not cholesterol → The shocking truth about statin drugs — and why heart disease has gotten WORSE since the 80s → How cholesterol-lowering drugs are literally shrinking your brain (the brain is 70% cholesterol) → The connection between statins, insulin resistance, and Alzheimer's (now called Type 3 Diabetes) → Why "all disease begins in the gut" — Hippocrates said it 2,000 years ago and it's still true → How estradiol reduced cardiovascular disease progression by 50% in women who already had plaque → Why testosterone is powerfully protective for men's hearts (not just for energy and muscle) → The one organ that can't make its own T3 thyroid hormone — your heart → Why your "normal" lab ranges are based on a sick population (and what optimal ACTUALLY looks like) → The phone scrolling habit that's destroying your melatonin AND your heart health → The inverse relationship between cortisol and DHEA that's wrecking your cardiovascular system → The vitamin D level that triggers a 5x cancer risk and 160% increased cardiovascular disease risk → The 6 hormones you need optimized for true heart disease prevention This isn't about managing heart disease with more prescriptions. It's about understanding the root cause — inflammation — and optimizing the hormones your body needs to protect itself. YOUR ACTION STEPS: Get a deep-dive lipid panel (particle size, ApoA, ApoB), check your hormone levels, ask about a coronary artery calcium score, and focus on OPTIMAL — not just "normal." TIMESTAMPS: 0:00 - Intro: It's Heart Health Month 2:15 - Heart disease is NOT a cholesterol problem 4:20 - The statin drug soapbox: billions in revenue, worse outcomes 6:40 - How statins are connected to Alzheimer's and insulin resistance 7:55 - It all begins in the gut: inflammation and lipid polysaccharides 9:05 - The one statin study — and why it doesn't apply to everyone 10:20 - Estrogen: a powerfully protective anti-inflammatory molecule 11:25 - The study showing 50% reduction in plaque progression with estrogen 14:05 - Testosterone: protective for cardiovascular disease in men 14:45 - Thyroid: the heart can't make its own T3 16:15 - Why "normal" lab ranges are based on sick populations 17:15 - Optimal Free T3 levels and what pediatric data actually shows 17:50 - Melatonin: the hormone you're destroying with your phone 19:10 - DHEA: the cortisol-DHEA inverse relationship 20:25 - Vitamin D: the hormone-like molecule with massive cardiovascular impact 21:20 - Recap: The 6 hormones for heart disease prevention ---- The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com ---- Connect with Dr. Terri DeNeui, DNP:

Wits & Weights: Strength and Nutrition for Skeptics
How Lifting Weights Improves Cardiovascular Health (Better Than Cardio?) | Ep 440

Wits & Weights: Strength and Nutrition for Skeptics

Play Episode Listen Later Feb 16, 2026 40:26 Transcription Available


Try Fitness Lab to get personalized daily coaching on nutrition, training, and biofeedback that adapts to how you want to train, whether you're focused on lifting, endurance, or both. Get 20% off through February 17:http://bit.ly/fitness-lab-pod20--You've been told cardio is for a healthy heart and lifting weights is for building muscle. But what if strength training is itself a form of cardio?What if you're ignoring one of the most effective tools for lowering blood pressure, improving cholesterol, and reducing your risk of heart disease?Philip breaks down the evidence showing that strength training lowers blood pressure on par with first-line medication, improves HDL and LDL cholesterol, enhances insulin sensitivity, and reduces visceral fat, all independent of cardio. You'll learn why your muscle tissue functions as a metabolic organ that regulates blood sugar, why adults who lift have up to 17% lower cardiovascular disease risk, and how to program your lifting sessions to get a real cardiovascular training effect without adding time on the treadmill. Philip also answers listener Jack R.'s question comparing cardio and lifting head-to-head for fat loss, muscle building, and long-term sustainability after 40. Whether you're already strength training over 40 or still treating the weight room as optional for heart health and longevity, this episode gives you the evidence-based case for making lifting your foundation.Timestamps:0:00 - Why "cardio for your heart" is incomplete 1:43 - The 2023 AHA statement about lifting weights and heart health 5:28 - How strength training lowers blood pressure as much as medication 7:11 - Nitric oxide, arterial stiffness, and improved blood vessels 9:27 - Cholesterol, triglycerides, and ApoB improvements 13:17 - Why muscle is your most powerful metabolic organ for insulin and blood sugar 15:20 - Cardio vs. lifting for fat loss and building muscle after 40 18:01 - Visceral fat, inflammation, and menopause 19:47 - Can lifting weights improve VO2max? 22:01 - Longevity data and the minimum dose of strength training for heart health 23:57 - How to get cardiovascular benefits WITHOUT extra cardio 26:04 - Rest periods, compound movements, and rep ranges for heart-healthy lifting 28:59 - Weekly template combining strength training and walking 30:59 - Physical reserve and why strength protects your heart all day 33:04 - Bonus: 10-second heart rate recovery test you can do between sets

The Boss Body Podcast
The Hidden Drivers of Chronic Illness: Mold, Inflammation & Authentic Longevity | Dr. Michele Neil-Sherwood, DO

The Boss Body Podcast

Play Episode Listen Later Feb 16, 2026 30:39


Are you frustrated with conventional medicine focusing on symptom management instead of root causes?   In this episode of the Boss Body Podcast, I sit down with Dr. Michele Neil-Sherwood, board-certified internal medicine physician and functional medicine expert, to unpack what's really driving chronic illness today.   We dive into advanced cardiovascular inflammation testing (ApoB, LP(a), LDL particle size), mold toxicity, mast cell activation, epigenetics, peptides like BPC-157 and Thymosin Alpha-1, and how molecular hydrogen and red light therapy support true healing.   Dr. Neil-Sherwood shares her powerful journey from corporate medicine to building a root-cause practice focused on authentic longevity — not just living longer, but living stronger.   If you want deeper answers, better labs, and a more strategic approach to your health — this episode is for you.  

Vitality Radio Podcast with Jared St. Clair
#613: Bad Medicine: Rethinking Cholesterol, Statins, and Heart Health

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Feb 14, 2026 34:00


On this episode of Vitality Radio, Jared takes a closer look at the cholesterol conversation and the widespread use of statin medications through a functional health lens. Rather than relying on fear or headlines, he explores how cholesterol numbers are interpreted, the difference between risk markers and root causes, and why metabolic health, inflammation, and lifestyle factors may play a larger role in long-term heart wellness. Jared also explains concepts like absolute risk, number needed to treat (NNT), and why informed decision-making matters when evaluating any health strategy. This episode encourages listeners to ask better questions, seek clarity, and consider a comprehensive approach to cardiovascular health that includes nutrition, movement, and targeted supplementation. As always, this discussion is educational and designed to empower you with information so you can make the best decisions for your personal health journey.Products:N.O. Cardio BoostVital 5 Omega-3 + AntioxidantsNatural Factors Rx Omega-3Natural Factors BerberineSolaray BerberineVital 5 Magnesium BisglycinateAdditional Information:#563: Bad Medicine: Why Your Gallbladder Isn't Disposable & How to Thrive With or Without It #332: Cholesterol Controversy - Jared's Interview on Inside The Aisle with Niki WolfeDr. Aseem MalhotraDr. Uffe RavnskovDr. Zoë HarcombeDr. Malcolm KendrickDr. David DiamondVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Just Think: The Podcast
"The Heart of the Matter" with Dr. Ben Schwartz

Just Think: The Podcast

Play Episode Listen Later Feb 13, 2026 62:37


In this episode we discuss the latest research the medical industry may not be telling you about your heart health. While statins dominate the conversation, groundbreaking research suggests cholesterol isn't the true villain—and your body actually needs it to thrive. If you're tired of feeling powerless over your health choices or overwhelmed by conflicting advice, this episode with Dr. Ben Schwartz is your game-changer. From prevention to disease reversal to treatment, we discuss it all, and with heart disease being the #1 killer of Amerians, you can't afford to stay uninformed.Timestamps:00:00 - Welcome and episode overview on heart health02:00 - Why heart disease remains the leading killer in America04:00 - Limitations of standard cholesterol tests and the need for advanced panels06:00 - How inflammation influences cardiovascular risk08:00 - Lifestyle factors: diet, sleep, stress management10:00 - Debunking cholesterol myths and the protective role of LDL12:00 - When statins may cause more harm than good15:00 - Natural supplements: red yeast rice and other alternatives18:00 - The significance of inflammation markers like APO-B, CRP20:00 - How emotional stress impacts the heart22:00 - The emerging science of infrared saunas and heat therapy25:00 - Recognizing early signs of a heart attack: symptoms and actions30:00 - How integrative medicine approaches can supplement conventional care35:00 - The importance of personalized risk assessment40:00 - Challenging the stories of the “big pharma” and industry influence44:00 - Practical steps to optimize heart health today50:00 - Resources, books, and tools for deeper understanding55:00 - Final encouragement: take ownership, be proactive, and stay informedResources & Links:Benton Integrative - www.bentonintegrative.com"First Do No Pharm" Film — nopharmfilm.comInfrared Sauna - www.Relaxsaunas.com (Use code: justthink200 for discount)

SISTERHOOD OF SWEAT - Motivation, Inspiration, Health, Wealth, Fitness, Authenticity, Confidence and Empowerment
Ep 897: Harvard Cardiologist Reveals the Silent Plaque Killing Americans with Dr. John Osbourne

SISTERHOOD OF SWEAT - Motivation, Inspiration, Health, Wealth, Fitness, Authenticity, Confidence and Empowerment

Play Episode Listen Later Feb 13, 2026 42:59


In this episode of Sisterhood of S.W.E.A.T., Linda Mitchell sits down with Dr. John Osborne, board-certified cardiologist, lipidologist, and founder of Clear Cardio, to challenge conventional thinking around cholesterol and heart disease. Dr. Osborne explains why LDL cholesterol alone is not a reliable standalone marker for cardiovascular disease and why focusing only on traditional lab numbers can create a false sense of security. He shares how plaque can quietly develop for decades before symptoms appear — and why the first symptom for many people is a heart attack or sudden cardiac event. The conversation explores the evolution of cardiac imaging, the role of ApoB and lipoprotein(a) in risk assessment, and how advanced cardiac CT combined with artificial intelligence now allows physicians to detect, measure, and track plaque in ways that were previously impossible. This episode reframes heart disease as something that can be identified early — and potentially prevented — when the right tools are used. What We Talk About in This Episode Why LDL cholesterol alone does not tell the full story The difference between risk factors and actual disease How ApoB improves cardiovascular risk assessment Why lipoprotein(a) is genetic and should be tested at least once The limits of traditional stress testing How plaque forms in the arterial wall decades before symptoms Calcium scoring versus full cardiac CT imaging How AI is transforming plaque detection and measurement Whether arterial plaque can be slowed or reversed The real role of statins and other cholesterol-lowering tools Why you cannot out-train genetics The one scan adults over 40 should consider Quotes from This Episode Cholesterol floating in your bloodstream does not tell me if it is sticking. Risk is not disease. The first question should be: do you have plaque? Half of men and two-thirds of women, their first symptom of heart disease is a heart attack or death. The problem is not that we cannot treat plaque. The problem is that we are not looking for it early enough. Early detection for heart disease should be as routine as screening for cancer. Connect with Dr. John Osborne Clear Cardio https://clearcardio.com Clear Cardio – Powers of Prevention YouTube Channel https://www.youtube.com/@ClearCardio Learn more about Cardiac CT and AI plaque analysis https://clearcardio.com/services/ Contact and Locations (Texas, Chicago, expanding to New York) https://clearcardio.com/contact/  

The Gary Null Show
The Gary Null Show - 2-11-26

The Gary Null Show

Play Episode Listen Later Feb 11, 2026 62:01


HEALTH NEWS A Simple Diet Change Could Slow Liver Cancer Brief, intensive exercise helps patients with panic disorder more than standard care Lucid dreaming could be used for mental health therapy, new study says US cancer institute studying ivermectin's ‘ability to kill cancer cells Too many saturated fats may be more harmful than too many refined carbohydrates.    Clips   Andrew Bridgen - https://x.com/ABridgen/status/2020573528571977993?s=20 MAHA Alliance Mike Tyson Super Bowl Commercial - https://www.youtube.com/watch?v=jg1SjFt1a_U   KETO DIET RISKS    The rationale for Keto Diet by its advocates Restricting carbohydrates, suppressing insulin and ketosis will lead to better metabolic heath, increase weight loss, reduce inflammation, and protect from chronic diseases.   Keto Claim: Carbohydrates raise insulin leading to fat storage – keto lowers insulin and burns body fat better Debunking: Ketosis is a metabolic state and not a health outcome. For example ketones can be elevated by very long fasting, starvation, different illnesses and uncontrolled diabetes.   Keto Claim: By minimizing carbs keto stabilizes blood sugar, reduce insulin spikes, and improve insulin sensitivity that benefits those with type 2 diabetes Debunked: This claim contradicts the evidence of induced hepatic insulin resistance and glucose intolerance in longer-term studies. In animal models, keto diets impair blood sugar regulation within several days, which shows harm for metabolic health.   Keto Claim: Ketones are seen as “clean” fuel that advocates claim are anti inflammatory and neuroprotective. Believe that this along with ketosis lowers triglycerides, raises HDL cholesterol, and improves lipid profiles. They argue that the increase in LDL cholesterol is benign. Claim saturated fats are harmless if carbs are low Debunked:  This claim is undermined by the increased LDL cholesterol, triglycerides, and cardiovascular risks from saturated fats in animal products. Meta-analyses show no long-term lipid improvements from keto diets. Rather this is the risk in elevated low-density lipoprotein and very-low-density lipoproteins that increase cardiovascular disease  Also, insulin reduction does not override the quality of fat. LDL cholesterol and ApoB, as well as atherosclerosis, increase significantly on an animal based diet. Saturated fat still remains a causal factor for cardiovascular disease.   Keto Claim: High protein and fat increases satiety and therefore reduces hunger Debunking: Weight loss is primarily from reduced intake due to satiety, not fat-burning efficiency. Long-term keto adherence often leads to weight regain with no significant sustained benefits for visceral fat or appetite control. hort term weight loss is not same as long term benefits. A study shows that weight loss at 3-6 months on a keto diet disappears by 12 months   Keto Claim: It enhances brain function and energy that then improves mental clarity and mood. Argue that animal products like eggs and organ meats provides choline and other nutrients for brain health. Debunked: There is no strong evidence for this claim. In fact keto's nutrient deficiencies and lack of fiber in the long term can lead to fatigue, constipation and in women neural tubal defects. Keto's claims are only based on short term trials.    Keto Claim: Use the evolutionary argument that humans evolved eating meat and fat – same argument the paleo folks used. Therefore, they believe keto diets align with human biology Debunked: A big study in Science in 2025 analyzed tooth enamel from skeletons of some of our oldest human ancestors, 3.5 million years ago, and found they ate predominately a plant based diet with no substantial sigh of mammalian meat. The isotopes matched herbivores (fruits, leaves and grasses, tubers, nuts, other vegetation) not carnivores.     Keto Diet Risks   It is worth noting, according to the Northwestern University Health site, there is a sizable drop out rate of participants in keto trials.   Although, there are studies that show keto does what it claims in the short term, there are no long-term human data to support their claims that an animal-based diet does this efficiently.   Important, research leans in the direction to indicate that keto's benefits – especially weight loss and glucose reduction, are transient and may not be directly related to animal food consumption itself but rather to calorie reduction and limiting glycogen.   Long term prospective studies and systematic meta analysis evaluations consistently show high red meat consumption, full-fat dairy and animal fats are associated with the following medical conditions. This is true even when carbohydrate intake is low   A good thorough study in JAMA shows that unprocessed red meat mildly increases all cause mortality – about 3-5% per 100 grams meat per day   High red and processed meat consumption increases carcinogenic N-nitroso compounds and heterocyclic amines that raise cancer risks by up to 18% per 50-100 grams/day – from meta analysis in the European Journal of Epidemiology   Dairy increases IGF-1 levels thereby too much calcium also suppressing Vitamin D and elevating prostate cancer risks by 79% per 400 gram dairy per day. Worse for processed meats that inreases risk by 21% per 20 grams/day – American Journal of Epidemiology   Red meat is linked to hormonal disruptions and carcinogens contributing breast cancer – European Journal of Cancer   Total unprocessed red meat consumption shows a modest 5% risk in pancreatic cancer per 100 grams/day. – From journal Clinical Nutrition   Many meta-analyses on meats have a relationship to stomach/gastric cancer, but processed meats are worse than unprocessed red meat. From study in Nutrients – 24 studies showed unprocessed red meat associated with gastric cancer by about 25% increase risk for every 100 grams/day.   Unprocessed red meat is linked to an 11% higher risk in overall cardiovascular disease risk due to inflammation and endothelial dysfunction. – from European Heart Journal   Saturated fats in meats increases non-HDL cholesterol and blood pressure and raises the risks of ischemic heart disease by 119% per 100 grams/day red meat – from American J Clinical Nutrition   Red meat diets reduce LDL Cholesterol much less than plant proteins and thereby increase atherosclerosis risks – from the journal Circulation   Red meats (an processed meats also in this study) contributes to insulin resistance via heme iron and raises Type 2 diabetes risks by up to 51% per 50 grams/day – International Journal Environmental Research in Public Health   Saturated fats in unprocessed red meat has a modest positive 12% increase with stroke risk – From  European Heart Journal Unprocessed poultry consumption shows a modest 4% increase in incident cardiovascular events per 100 grams/day. This is believed to be due to arachidonic acid poultry – in JAMA   Red meat contributes to sodium and saturated fat intact raising hypertension conditions by 14% per 50-100 gram/day – from journal Advanced Nutrition   Saturated fats from animal products cause lipotoxicity and insulin resistance, that promotes hepatic fat accumulation leading to non-alcoholic fatty liver disease – from Cardiovascular Development and Disease   High animal protein increases urinary calcium and acid overload leading to the formation of kidney stones – from the journal Nutrient   Animal-heavy diets have low fiber and micronutrient intake that contribute to nutrient deficiencies. Also causes constipation that can lead to immune system issues. – from the journal Nutrients   Red meat, dairy, and eggs disrupts the gut metabolism of carnitine and choline. This promotes TMAO plaque formation and inflammation that leads to atherosclerosis. – from Journal of Cardiovascular Development.   Although unprocessed meat consumption has not been adequately associated with dementia and Alzheimer's – yes, processed meats do – there are studies showing red meat is associated with “subjective cognitive decline” (SCD) which is related to precursors to dementia and Alzheimer's. A study in journal Neurology  links unprocessed red meat eaten at 1 or more servings per day to 16% higher risk in SCD.   High caloric density from saturated animal fats displaces fiber that contributes to weight gain obesity. From Neal Barnard in the American Journal of Clinical Nutrition   Animal products transmit prions that are associated with neurodegenerative disorders.  Proinflammatory compounds like TMAO are linked to neurological risks. – in International Journal of Molecular Science

GRUFFtalk How to Age Better with Barbara Hannah Grufferman
Must-Have Heart Health Tests for Postmenopausal Women EP 186

GRUFFtalk How to Age Better with Barbara Hannah Grufferman

Play Episode Listen Later Feb 10, 2026 13:40


Subscribe to AGE BETTER CHEAT SHEET Newsletter on Substack HERE   PRINT THIS AND TAKE IT WITH YOU TO YOUR NEXT ANNUAL PHYSICAL EXAM:   ESSENTIAL BLOOD WORK SCREENING TESTS CHEAT SHEET   February is AMERICAN HEART MONTH, so we're replaying this solo episode where I dive into the essential blood tests and health screenings every postmenopausal woman should ask about during your annual physical. Drawing on expert insights from past episodes, I talk through why it's crucial to go beyond routine tests and discuss additional screenings that can help detect potential health risks early.   WHAT I COVER IN THIS EPISODE:   - The importance of the lipid panel for understanding heart health.   - How the Apolipoprotein B (ApoB) test provides a more accurate cardiovascular risk assessment.   - Why high levels of C-reactive Protein (CrP) can indicate dangerous inflammation levels.   - The critical role of Vitamin D for bone and immune health, especially in midlife women.   - How regular blood glucose testing can help catch diabetes early.   - The significance of blood pressure monitoring for heart disease prevention.   - Why women should prioritize bone density tests to prevent osteoporosis.   - The importance of monitoring  waist circumference as an indicator of health risks.   - The need for regular cancer screenings, including Pap smears, mammograms, and colonoscopies, for early detection.   - Regular cancer screenings are essential for early detection.   KEY LINKS TO LEARN MORE:  Learn more about the ApoB test HERE  Learn more about the LP(a) test HERE    Learn more about inflammation HERE   Learn more about heart health and atrial fibrillation HERE   Learn more about blood glucose and insulin resistance HERE   CONNECT WITH ME:  Instagram: @BarbaraHannahGrufferman     X/Twitter: @BGrufferman   Facebook: @BarbaraHannahGruffermanAuthor   Please Rate & Review the Show!     If you enjoyed today's episode, please consider leaving a review or sharing it with someone who would benefit from these essential health tips.   Learn more about your ad choices. Visit megaphone.fm/adchoices

Well-Fed Women
LDL, Inflammation, and Estrogen: A Smarter Look at Cardiovascular Health

Well-Fed Women

Play Episode Listen Later Feb 3, 2026 60:58


Midlife health is about far more than a single lab value. In this episode, we talked about how hormones, muscle mass, cholesterol, and inflammation influence long term heart and metabolic health. If you've ever felt overwhelmed or confused by what to focus on, we're bringing the clarity and direction to make it easier on you!Timestamps:[1:50] Welcome[11:52] I saw a post that said muscles in our legs help us have longevity and our calf muscles are like the second heart in the body. I'm assuming there's some truth, but does that just mean to continue to strike train and to walk?[24:56] How do you know if you're in peri-menopause? I feel like everything is a symptom.[37:24] What are the pros and cons of muscle splits vs. whole body workouts?[45:25] What dietary guidance do you have for lowering high total cholesterol? Episode Links:Kicking Back Cognitive Aging: Leg Power Predicts Cognitive Aging after 10 Years in Older Female TwinsSeeking Health DAO enzymeSeeking Health Histamine ProbioticThyroid Markers to check: TSH, Free T4, Free T3, Thyroid peroxidase antibodies (TPO), Thyroglobulin antibodies (TGAb)Additional cholesterol markers to check: ApoB, LDL-P, hs-CRP, fasting insulinSponsors:Go to boncharge.com/WELLFED and use coupon code WELLFED to save 15% off any order.Go to getkion.com/wellfed to get 20% off your order. Go to http://mdlogichealth.com/wfcolostrum , and use coupon code WFC15 for 15% off. You can also use code WELLFED for 10% off site wide on all MD Logic Products. Go to wellminerals.us/vitaminc and use code WELLFED to get 10% off your order.

Vroom Vroom Veer with Jeff Smith
Dr. Will Haas – Take Charge of Your Health

Vroom Vroom Veer with Jeff Smith

Play Episode Listen Later Feb 2, 2026 51:08


Dr. Will Haas, MD, MBA is redefining what it means to age well. He is the Founder and CEO of VYVE Wellness in Charlotte, NC, where he helps high-achieving professionals reclaim energy, focus, and vitality through cellular optimization. Board-certified in Integrative and Family Medicine, Dr. Haas blends advanced therapies—IV nutrient infusions, therapeutic peptides, hyperbaric oxygen, and red light therapy—to deliver measurable results that help patients feel decades younger. Beyond VYVE, he co-founded OvulifeMD, creating natural fertility protocols, and serves as Chief Medical Officer at Infusive, supporting wellness practices nationwide. His expertise has been featured in Men'sJournal, Daily Mail, Yahoo Life, and Woman's World Magazine. Passionate about bridging science with practical results, Dr. Haas empowers high-performers who want more than just longevity—they want their best years ahead of them. Dr. Will Haas Vroom Vroom Veer Summary Journey to Integrative Medicine William shared his journey from medical school to finding his passion in integrative medicine, which focuses on using a variety of healing modalities to optimize health. He initially struggled with the conventional approach to medicine, which primarily focuses on treating diseases, and decided to pursue business studies during his medical training. However, a personal loss led him to fulfill his father's dying wish to complete his medical degree. William eventually found his calling in integrative medicine, which he believes should be the standard approach to healthcare, combining the best of conventional and alternative treatments. Cellular Optimization and Health Strategies Jeffery and William discussed the concept of cellular optimization and the importance of addressing toxins and oxidative stress in the body. They explored how factors like poor diet, lack of sleep, and environmental exposure can contribute to cellular damage and reduced energy levels. Jeffery shared his personal experience of reducing sugar and processed foods intake, which led to improved health and well-being. They also touched on the idea of getting a CT scan for a calcium score as part of a proactive approach to prevent heart attacks. Cardiovascular Health Assessment Strategies Jeffery and William discussed cardiovascular health, diagnostic tests, and therapeutic peptides. William explained the importance of assessing inflammation levels, homocysteine, and other markers to evaluate heart attack risk. They talked about the benefits of advanced lipid panels and the role of Apo B and oxidized LDL in predicting cardiovascular events. William shared a success story of a patient who improved his health through dietary changes, gut healing, and IV nutrient therapies. They also briefly discussed the potential of therapeutic peptides under medical supervision. Connections Website

Everyday Wellness
Ep. 548 “It's Not Just LDL” – How Menopause Alters Cholesterol, ApoB & Lp(a) | Menopause & Lipids

Everyday Wellness

Play Episode Listen Later Jan 29, 2026 22:02


We have another short-form, live YouTube episode today, where I dive into questions from listeners. Recently, the most frequently asked questions have been about cholesterol, likely because I often reference my podcast series with Dr. Tom Dayspring, a renowned lipidologist and menopause expert. Join me today to clear away some more of the confusion surrounding cholesterol. IN THIS EPISODE, YOU WILL LEARN: Why comprehensive lipid testing rather than standard testing is essential, post-menopause How menopause impacts women's lipid and triglyceride levels The roles APO B and Lp(a) play in assessing cardiac risk How the cardiac risk of women increases as estrogen declines The cardiac health benefits of monitoring lipids and considering HRT within the first six years of menopause What research studies reveal about how menopause influences cardiovascular risk Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Episodes with Dr. Thomas Dayspring: Episode 336: Lipid Masterclass: An Introduction to Lipids and Cholesterol with Dr. Thomas Dayspring Episode 344: Lipid Masterclass: A Deep Dive into Our Cardiovascular Needs with Thomas Dayspring Episode 352: Lipid Masterclass: Apo-B, Labs and Women's Heart Health with Thomas Dayspring Episode 495: Are You At Risk for Dementia? – The Most Overlooked Cholesterol Marker You Need to Know with Dr. Thomas Dayspring

Brain Biohacking with Kayla Barnes
Dr. Jessica Shepherd, MD – Menopause, Hormone Therapy and Bone Health

Brain Biohacking with Kayla Barnes

Play Episode Listen Later Jan 29, 2026 49:13


In this episode, Dr. Jessica Shepard, board-certified OB/GYN and Chief Medical Officer of Hers, shares that the FDA just removed the black box warning on hormone replacement therapy after 23 years. We discuss what actually happened with the WHI study that created all the fear around estrogen and breast cancer, and why the research never actually supported that narrative.Dr. Shepard explains why you shouldn't wait until menopause to start the HRT conversation and how starting in your perimenopausal years can make all the difference for long-term health. Dr. Shepard shares the essential labs she runs on patients including ApoB, HbA1c, and thyroid optimization, plus the longevity metrics women should be tracking.We also get into supplement recommendations including why she recommends 10 grams of creatine daily, the role of inflammation in aging, and how estrogen is naturally anti-inflammatory which is why women see increased cardiovascular risk and metabolic dysfunction after menopause.Kayla's social + website:Instagram:  kaylabarnesTikTok:  femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comSpotify: https://open.spotify.com/show/4OLWWn2...Apple: https://podcasts.apple.com/us/podcast...Follow Her Female Protocol: https://www.protocol.kaylabarnes.comDr. Jessica Shepherd's social + website:Website: https://www.jessicashepherdmd.com/Instagram: https://www.instagram.com/jessicashepherdmd/Transform Your Health: https://eudemonia.net/?utm_source=podcast&utm_medium=kayla-podcast&utm_campaign=jessica-shepherd

Peak Performance Life Podcast
EPI 236: The Most Important Blood Biomarkers You Should Be Tracking Regularly (Your Doctor Probably Isn't Testing Them). With Longevity Medicine Specialist Dr. Darshan Shah

Peak Performance Life Podcast

Play Episode Listen Later Jan 27, 2026 45:03


Show notes: (0:00) Intro (0:49) Dr. Shah's background and personal health crisis (4:55) The most important biomarkers: hs-CRP, A1C, ApoB (7:46) How to track inflammation and metabolic health (13:00) Home tools: bioimpedance scale, grip strength meter (21:09) Nutrition basics: just cut ultra-processed foods (27:09) Hidden toxins in your air, water, and skincare (34:37) Longevity circuit: sauna, cryotherapy, hyperbaric oxygen (38:11) Therapeutic plasma exchange and next-gen biohacking (40:01) Dr. Shah's top 3 health tips anyone can start today (41:18) Where to find Dr. Shah (42:11) Outro Who is Dr. Darshan Shah?   Darshan Shah, MD is a health and wellness specialist, well-known, board-certified surgeon, published author, tech entrepreneur, and founder and CEO of Beautologie and Next Health. As an expert on all body systems, he has performed over 10,000 surgical procedures, including trauma surgery, general surgery and plastic/reconstructive procedures. As a health and wellness specialist, he has advised thousands of patients on how to optimize their well-being and extend their lifespan, culminating in the creation of Next Health, the first health optimization and longevity center to offer life-extending and enhancing technology and treatments in a beautiful, welcoming environment.   Connect with Dr. Shah Website: https://www.drshah.com/ LinkedIn: https://www.linkedin.com/in/darshanshahmd IG: https://www.instagram.com/darshanshahmd/   Grab your free Biomarker guide: https://www.drshah.com/biomarkers   Tune in: https://www.drshah.com/extend Links and Resources: Peak Performance Life Peak Performance on Facebook Peak Performance on Instagram

Wellness at the Speed of Light
Inside Cardiovascular Risk with Dr. Michael Richman

Wellness at the Speed of Light

Play Episode Listen Later Jan 24, 2026 122:37


In this episode of Wellness at the Speed of Light, Dr. Stefano Sinicropi speaks with Dr. Michael Richman, a double board-certified cardiothoracic surgeon with deep expertise in lipidology and cardiovascular prevention. They unpack why cardiovascular disease remains the leading cause of death for both men and women, and why many people labeled “low risk” are still vulnerable to heart attack or stroke. This audio conversation focuses on how atherosclerosis develops over time, the major drivers of cardiovascular risk, and why genetics play a larger role than most people realize. Dr. Richman explains the practical difference between standard cholesterol testing and particle-based measurements such as LDL-P and ApoB, and why these tests can help identify risk earlier and more accurately. They also address the nocebo effect and the way health misinformation shapes patient beliefs and decision-making. The discussion covers the evidence behind statins, including plaque stabilization and inflammation, as well as common questions about omega-3 fatty acids, niacin, red yeast rice, and calcium scoring. The goal is to give listeners a clearer framework for understanding cardiovascular risk, asking better questions in clinical settings, and taking informed, prevention-focused steps without relying on hype or trends. Guest: Dr. Michael Richman, MD, double board-certified cardiothoracic surgeon and lipidology expert.

Growing Older Living Younger
247 Carnivore vs Whole Foods: An N-of-1 Experiment on Epigenetics, Nutrition and Healthspan with Dr. Andres Ayesta

Growing Older Living Younger

Play Episode Listen Later Jan 23, 2026 47:10


Extreme diets dominate social media, but what actually happens inside your body when you follow them? In this episode, registered dietitian Andres Ayesta shares the results of a 60-day self-experiment comparing a carnivore diet with a whole-foods, minimally processed approach. Using lab testing, DEXA scans, and behavioral science, he reveals what truly changes—and what doesn't—when it comes to weight, body composition, energy, and long-term health as we age. Andres Ayesta is a registered dietitian, sports nutritionist, and founder of Planos Nutrition. With over 12 years of experience, he helps busy professionals over 30 lose fat, improve energy, and build sustainable habits using evidence-based nutrition and behavior change strategies. His work bridges clinical science with real-world practicality.  Episode Timeline 00:00 — Introduction and why this experiment matters  03:10 — Carnivore vs whole foods: defining the diets  08:45 — Designing a real-world, controlled self-experiment  15:30 — Energy, hunger, and the keto adaptation phase  21:30 — Lab results: cholesterol, ApoB, and liver markers  27:45 — DEXA scan findings and body composition truth  33:30 — Sustainability, behavior, and why diets fail  38:30 — The Core Five habits for lasting lifestyle change  44:00 — One action step listeners can start this week   Action Steps:  Download Guide to Nature's Coloful Antioxidants  Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show.  Join the Growing Older Living Younger Community Connect with Dr. Gillian Lockitch at ASKDRGILL Connect with the Guest Instagram: https://www.instagram.com/andresayesta YouTube: https://www.youtube.com/@andresayesta TikTok: https://www.tiktok.com/@andresthedietitian LinkedIn: https://www.linkedin.com/in/andresayesta Website: https://planosnutrition.com/  

DozeCast - Cardiologia
Diretriz Brasileira de Dislipidemias e Prevenção - SBC 2025 (DozeCast 208)

DozeCast - Cardiologia

Play Episode Listen Later Jan 22, 2026 79:21


A dislipidemia deixou de ser um tema restrito a “colesterol alto” e a Diretriz Brasileira de 2025 veio para deixar bem claro que o foco é prevenção da aterosclerose e suas repercussões em desfechos cardiovasculares!No DozeCast #208, Victor Bemfica e Diandro Mota discutem os principais destaques da nova diretriz e o que, de fato, muda na prática clínica.Falamos sobre:• Atualizações na estratificação de risco e tomada de decisão clínica• Metas lipídicas e marcadores adicionais (não-HDL, ApoB, Lp(a))• Estratégias de tratamento: intensificação precoce e terapias combinadas quando indicado• Papel das terapias hipolipemiantes modernas: anti-PCSK9, inclisiran, ácido bempedoico, entre outras • Condutas em populações específicas (diabetes, DRC, idosos e alto risco)

Biohacking Superhuman Performance
#405: Heart Attacks Aren't What You Think | The Plaque LIE That Changes Everything (Cardiology 2.0) With Dr. Sanjay Bhojraj

Biohacking Superhuman Performance

Play Episode Listen Later Jan 20, 2026 91:45


Today, I'm joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described "curious cardiologist" who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it?   Episode Timestamps: Welcome to Longevity & episode setup … 00:00:00 Dr. Bhojraj's shift from ER cardiology to prevention … 00:06:30 Why most heart attacks aren't caused by big blockages … 00:09:15 Stress, nervous system load & heart attack risk … 00:13:10 CIMT explained: what it measures (and what it misses) … 00:26:40 Calcium scores vs CT angiograms … 00:35:45 CLEERLY scan: seeing dangerous soft plaque … 00:38:45 Can plaque actually regress? … 00:41:55 When heart scans make patients less afraid … 00:44:05 When should you test — even without symptoms? … 00:45:50 Why age 45 is a major cardiovascular inflection point … 00:47:10 Hormones, estrogen loss & women's heart risk … 00:50:10 Why cardiology still misunderstands women … 00:54:30 Small dense LDL, ApoB & oxidized cholesterol … 01:02:00 Why fixing inflammation matters more than numbers … 01:05:50   Our Amazing Sponsors: Regenerive - Built around clinically validated Longufera (Ash X4) to support core aging pathways—so it's not just "healthy aging" in theory. Go to regenerive.co and use code NAT25 to save 25%   Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026.   PW1 by Puori — A clean, high-quality whey protein that's third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Health Longevity Secrets
When ‘Normal Labs' Are Unhealthy with Sandeep Palakodeti MD

Health Longevity Secrets

Play Episode Listen Later Jan 20, 2026 46:13 Transcription Available


Feeling “fine” is not a plan. We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your ultimate asset can change the arc of your life. We dig into the core four foundations (sleep, diet, exercise, relationships), the hidden risks behind “normal for your age” labs, and the personalized strategies that help you extend your prime years, not just your lifespan.Sandeep explains the gaps in standard panels and why markers like lipoprotein(a), ApoB, and early insulin resistance can quietly raise cardiovascular risk for decades. He shares a practical framework for advanced therapies—rapamycin, peptides, red light, hyperbaric oxygen—rooted in evidence, safety, access, and intent, with explicit stop criteria to avoid blind experimentation. We talk through what it takes to turn vague advice into precise action: strength training as a glucose sink, protein targets, VO2 max, and sleep protocols tailored to your biology and lifestyle.We also explore the evolutionary case for a longer, more productive middle life. Wisdom tends to peak in the 50s and 60s, exactly when chronic disease often accelerates. With the right diagnostics, coaching, and accountability, it's possible to keep the energy of a 30-year-old while preserving the judgment of a seasoned leader. From there, we shift to AI's growing role in medicine: clinical copilots that surface patterns, agentic systems that handle routine care, and how empathy at scale could emerge alongside human guidance for high-stakes decisions.If you're ready to manage health with the same rigor as your wealth, this conversation offers a roadmap: better measurement, longer conversations, smarter tools, and a clear strategy that compounds over time. Subscribe, share with a friend, and tell us—what metric will you start tracking this week?https://www.velocityhealthclinic.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Blu...

NeuroEdge with Hunter Williams
Cardarine for Longevity and Performance | Revisiting GW-501516 in 2026

NeuroEdge with Hunter Williams

Play Episode Listen Later Jan 20, 2026 23:44


Join My Private Group: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://theaxioncollective.manus.space/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email List: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://huntershealthhacks.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Get My Book On Amazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/avbaV48Download⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Peptide Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://peptidecheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Download The Bioregulator Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bioregulatorcheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1 On 1 Coaching Application: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscoaching.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Book A Call With Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscall.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Supplement Sources: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamssupplements.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Storefront: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Socials:Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/hunterwilliamscoaching/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Video Topic Request: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamsvideotopic.carrd.co/⁠⁠⁠In today's episode, I'm finally circling back to one of my favorite research compounds that I don't talk about nearly enough: Cardarine (GW501516). I've used it for years in a cycled on, cycled off way, because when it works, it really works. The two big reasons people care about Cardarine are simple. Endurance and lipids.I break down why endurance athletes love it, why it makes cardio feel almost effortless for me within a week or two, and why it's not “a stimulant fat burner,” but can still absolutely support a fat loss phase when your training and diet are dialed in. Then we get into the science. I walk you through the background, how it was developed as an “exercise in a pill,” and the human trial data showing improvements in HDL, triglycerides, ApoB, liver fat, and insulin markers.And yes, we address the elephant in the room: the rodent cancer findings, the lack of long-term human data, and how I personally think about risk, dosing, and cycling. I'm not here to tell you what to do. I'm here to give you the data, how I interpret it, and let you make an informed decision.Also, at the end, I tease another compound you may want me to cover next: GW0742.

LowCarbUSA Podcast
Dave Feldman on Cholesterol Code & Why the Science Isn't Settled Yet: Ep 127

LowCarbUSA Podcast

Play Episode Listen Later Jan 14, 2026 32:48


When Dave Feldman first walked into a LowCarbUSA® event in 2016 carrying a laptop full of lab results, few people could have predicted where that moment would lead.  "I'm approaching everyone with my computer," Feldman recalls, "because I'm doing these self-experiments—getting blood work—and I'm trying to figure out why my cholesterol numbers were doing what they were doing."  What started as a personal puzzle became The Cholesterol Code, a global research effort, a nonprofit scientific foundation, and now a forthcoming documentary film. In this episode of the LowCarbUSA Podcast, host Doug Reynolds sits down with Feldman to trace that journey—and to explain why the next chapter will take center stage at the Symposium for Metabolic Health in Boca Raton, January 23–25, 2026 The Question That Wouldn't Go Away Dave's original question was deceptively simple: Why do some metabolically healthy, lean people see their LDL cholesterol rise dramatically on a ketogenic diet?  Over time, he noticed a consistent pattern. These individuals didn't just have high LDL—they also tended to have high HDL, low triglycerides, and excellent metabolic health. In 2017, he coined a name for this group: Lean Mass Hyper-Responders (LMHRs). But identifying a pattern wasn't enough.  "Even if the lipid energy model proves correct," Dave explains, "does that mean having higher LDL on a ketogenic diet carries higher cardiovascular risk?"  Answering that question required something far more difficult than a blog post or a hypothesis: a prospective imaging study. Building a Study When No One Will Fund One Dave spent years trying—and failing—to convince established institutions to study this population.  "There's not a lot of funding to study metabolically healthy people with sky-high LDL," he says dryly. "The interest is usually in people who already have multiple cardiovascular risk factors—which confounds everything."  So in 2019, he made a radical decision. He founded the Citizen Science Foundation, a public charity created for a single purpose: to fund independent research, with no money going to salaries or overhead.  "We raised $200,000,"Dave says, "and paid a research center to do the study."  By late 2021, recruitment was underway. One hundred lean, metabolically healthy ketogenic individuals underwent coronary CT angiography (CTA) scans to assess plaque in their coronary arteries, with follow-up scans roughly one year later. What the Data Actually Showed The early findings were striking.  When Dave's cohort was matched against participants from the Miami Heart Study, there was no statistically significant difference in coronary plaque, despite Dave's group having LDL levels less than twice as high.  "In fact," he notes, "our group trended toward lower plaque." But the most important finding emerged as more analyses were completed:  "There was no association between ApoB or LDL and plaque progression," Dave says. "Whatever your LDL level was, it did not correspond with how plaque developed."  What did matter? Baseline plaque. "Whether you're low-carb or not," he explains, "the more plaque you have at baseline, the more likely you are to see progression. That's consistent with the existing literature." When One Dataset Didn't Make Sense Then came the controversy.  An AI-based quantitative analysis from a company called Cleerly showed plaque progression that appeared inconsistent—not only with Dave's other data, but with decades of prior research.  "All of the scans showed progression," he says. "No regression. Not even noise."  For an engineer, that raised immediate red flags.  "If a bathroom scale is off by a quarter pound," Dave explains, "you expect wobble.  Below the noise floor, measurements go up and down.  But this dataset showed only one direction." Later, when Dave gained access to the anonymized data, he identified multiple anomalies and requested a blinded quality-control reanalysis.  That request was declined.  "I don't assume wrongdoing," he emphasizes. "But when something looks implausible, the response should be course correction."  Instead, he sought independent confirmation.  A second AI company, HeartFlow, conducted a fully blinded analysis—and its results aligned with every other analysis except Cleerly's.  "Three out of four analyses agree," he says. "Cleerly is the outlier." Why This Matters Beyond One Study The implications extend far beyond a single dataset.  Dave believes this episode exposes a deeper issue in nutrition and cardiovascular science: how dominant theories shape interpretation.  "The lipid hypothesis has a gravitational pull," he says. "It affects what people expect to see—and what they question."  As I put it, Dave has repeatedly taken the LowCarbUSA stage to announce findings that challenge assumptions—and each time, the conversation moves forward.  "If we want better answers," Dave says, "we have to do better science." The Documentary—and What Comes Next All of this has reshaped his upcoming documentary, The Cholesterol Code. Originally slated for release last year, the film has been expanded to include the scientific and human story behind these findings.  "We couldn't release it without covering what happened," he explains. "It's part of the truth."  For the first time anywhere, the official trailer for the film will be shown at the LowCarbUSA Symposium in Boca, immediately following Dave's talk.  Attendees will also be invited to help bring the film to live screenings around the world.  "The world premiere of the trailer will be at your conference," Dave told me.  "That alone is worth coming for." Why You'll Want to Be There One full day of the Boca symposium is dedicated to cardiovascular health, and Dave is one of the central voices shaping that conversation. Whether you attend in person or via live stream, this is a rare opportunity to engage directly with research that is still unfolding—and with the scientist who helped drive it. As Dave puts it: "The work just needs to get done,  and in Boca, it will." Learn more and reserve your in-person or virtual seat for the Boca Symposium for Metabolic Health (January 23–25, 2026)

The Cool Fireman Podcast
#141 Firehouse Nutrition & Fitness: Whole Foods, Better Sleep, and Sustainable Progress

The Cool Fireman Podcast

Play Episode Listen Later Jan 12, 2026 39:44


The guys kick things off with some classic pre-show chaos (storms, Starlink, “Wicked” talk, hay and horses) before shifting into a real conversation about health and fitness in the fire service. Freddy frames it as a “new year” topic—less about resolutions and more about lifestyle consistency—and Matt shares his on-duty heart attack story as a reminder that being “in shape” doesn't automatically equal being protected. They dig into nutrition habits, added sugar, energy drinks, sleep, accountability apps, and the idea that the goal isn't a number on the scale—it's being capable on the worst call of your career.Key Topics & MomentsWeather, Starlink, and Farm LifeWind gusts, Starlink shifting in the yard, and the dream of stable internet for streaming youth sports.Doug's day includes hay pickup and a farrier visit (hoof care)—Matt learns a new word.Quick ShoutoutHappy Birthday to “GG” (the outro celebrity) — the crew encourages listeners to comment birthday wishes.Patreon UpdatesThe crew thanks new and ongoing Patreon supporters and starts a “virtual turnout drill” segment:Subscriber spotlight questions like sunrise vs sunset, favorite sandwich, and bucket list.Merch store is still live, with the tease that Patreon members may get exclusive items.SponsorsUnkie's SeasoningTom / The Burnbox (including mention of their latest box and the “calendar”)Main Topic — Fitness, Diet, and Being ReadyFreddy sets the tone: our job isn't compatible with “fitness rollercoasters.” Staying ready matters because you never know which run will test you.Matt's On-Duty Heart Attack (Oct 18, 2022)Matt shares he had a heart attack on duty with no warning signs, despite being active and in good shape.He believes his fitness level helped him survive and recover.He talks about how it changed his mindset around diet, sugar, lifestyle, and annual health checkups.He mentions deeper cholesterol metrics like ApoB and Lp(a) and encourages listeners to talk with their cardiologist—especially with family history.The “Skinny but Unhealthy” TrapMatt describes being the “fattest skinny guy you ever met” (lots of sugar, sweets, and junk).Discussion of insulin resistance as something worth learning about and paying attention to.Freddy's Reset: Sleep, Energy Drinks, Added SugarFreddy shares his own weight swings and what derailed him: school schedules, stress, poor sleep, energy drinks.He's rebuilding with:30 minutes of daily movementZone 2 cardioCutting energy drinks and sodaReducing added sugarsUsing protein powder in coffee as a “mocha” hackDaily pushups + squats challenge (and the struggle of wanting instant results)Doug's Take: Whole Foods > Processed FoodsDoug leans into the “back to basics” approach:More whole foods, fewer lab-made processed foodsWater over sodaBlack coffee and cutting sugar where possibleHe gives a nod to Megan at RescueRD as a resource for nutrition guidance (and suggests having her back on).Apps & Tools MentionedBevel (Freddy): fitness tracking, calories/macros, accountabilityMyFitnessPal (Freddy): previous trackerYuka (Matt): barcode scanner that rates foods and highlights additives/ingredientsEncouragement to take advantage of wellness programs: labs, ECG, treadmill, etc.Snail Mail HighlightsListener Zach shares his 2026 word(s): Seek and Trust (faith, academy prep, baby #3, trusting the process).Colt shares appreciation for the ICS conversation and downloads What3Words after the episode.Quotes to Pull for Clips“This job isn't compatible with rollercoasters. You've gotta stay ready.”“Make it a lifestyle. If you stop, you feel off.”“I was the fattest skinny guy you ever met.”“If you've got family history—get a cardiologist. Once a year.”“You were treating the monitor, not the patient.”Call to ActionWhat lifestyle change are you making in 2026?Not a “resolution”—a real, achievable shift that makes you better for your department, your family, and yourself.Drop yours in the comments.

The Most Days Show
Dr. Todd Dorfman on Brent's Latest Heart Procedure

The Most Days Show

Play Episode Listen Later Jan 9, 2026 56:11


This week, Brent speaks with his personal physician, Dr. Todd Dorfman, for an update on his own health journey. Using Brent as a real-world case study, they walk through the discovery of an anomalous coronary artery, the risks and benefits of advanced cardiac diagnostics, and why more testing isn't always better. The conversation then shifts to prevention. Dr. Dorfman shares how he thinks about cholesterol, ApoB, Alzheimer's risk, statins, PCSK9 inhibitors, GLP-1 drugs, and other emerging therapies when you don't have disease but want to stay ahead of it. As always, Dr. Dorfman is a wonderful guest. Hope you enjoy.

Live Lean TV with Brad Gouthro
The Cholesterol Myth: The Heart Disease Markers You Actually Need to Track

Live Lean TV with Brad Gouthro

Play Episode Listen Later Jan 6, 2026 7:49


Go to my sponsor https://trylco.com/liveleanheart and use code LiveLeanHeart to get 20% off the Comprehensive Heart Health and other select tests. Get the insights you need to live a healthier life. Heart disease is the #1 cause of death, and most people don't realize their risk is building silently for decades, even if their cholesterol test looks “normal.” In this episode of Live Lean TV, I break down why your standard cholesterol panel is missing the most important heart disease markers, and what Dr. Peter Attia actually recommends tracking for long-term cardiovascular health and longevity. According to Dr. Peter Attia, your total cholesterol number is only slightly more relevant to heart disease risk than your eye color. Instead, the real predictors are ApoB and Lp(a), two blood markers most people never test. ► Free 7 Day Trial To My Workout App: https://www.liveleantv.com ► Live Lean Body Quiz: https://www.liveleantv.com/quiz ► Free 7 Day Meal Plan And Recipes: https://www.liveleantv.com/free-stuff ⏱️ Table of Contents 00:00 Intro 00:59 Why You Need To Be Aware Of Cardiovascular Disease In Your 30's and 40's 01:32 ApoB: Your Cholesterol Test Is Missing This Heart Disease Marker 02:16 Why Lp(a) Testing Is Important For Cardiovascular Disease Risk 04:31 The Truth About Dietary Cholesterol And Heart Disease 05:53 HDL vs LDL Cholesterol Levels: What's The Difference In this video, you'll learn: ► Why heart disease risk starts building in your 30s and 40s ► What ApoB is and why it matters more than LDL cholesterol ► Why Lp(a) is a genetic risk factor you should test at least once ► The truth about dietary cholesterol, saturated fat, and heart disease ► HDL vs LDL explained in simple terms ► Why standard cholesterol tests can give a false sense of security ► The exact blood markers I personally track for heart health and longevity Subscribe Here! http://bit.ly/SubLiveLeanTV Check Out Our Top Videos! http://bit.ly/LiveLeanTVTopVideos Read the blog here: https://www.liveleantv.com/blog Listen to the podcast here: https://www.liveleantv.com/podcast WANT MORE DAILY TIPS ON HOW TO LIVE LEAN?: ► INSTAGRAM: http://www.instagram.com/bradgouthro ► INSTAGRAM: http://www.instagram.com/JessicaGouthroFitness ► INSTAGRAM: http://www.instagram.com/LiveLeanTV ► SNAPCHAT: https://www.snapchat.com/add/bradgouthro ► FACEBOOK: https://www.facebook.com/LiveLeanTV ► TWITTER: https://www.twitter.com/bradgouthro ► TWITTER: https://www.twitter.com/LiveLeanTV ► TIK-TOK: https://www.tiktok.com/@bradgouthro ► TIK-TOK: https://www.tiktok.com/@liveleantv #cholesterol #hearthealth #LiveLeanTV About Live Lean TV: Welcome to Live Lean TV. The online fitness and nutrition show, hosted by Brad and Jessica Gouthro, teaching you how to LIVE THE LEAN LIFESTYLE 365 days a year. Watch hundreds of fat blasting & muscle building workouts, easy and delicious recipes, as well as fitness and nutrition tips to get you your dream body (and maintain it 365 days a year). Make sure you click the SUBSCRIBE button for new fitness and nutrition episodes every week! Business Enquiries: info@LiveLeanTV.com Why Your Cholesterol Test Is Lying to You (ApoB, Lp(a), & Heart Disease Explained) https://youtu.be/bmALZ2tKGBA Live Lean TV https://www.youtube.com/LiveLeanTV

Health Longevity Secrets
What if the Future of Medicine is in Your Home?

Health Longevity Secrets

Play Episode Listen Later Jan 6, 2026 35:33 Transcription Available


What if the most powerful health checkup you ever had happened at your kitchen table, not a clinic? We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade at‑home blood testing and intelligent coaching can change outcomes before a crisis hits.We start with the problem he saw repeatedly: people arriving late with preventable chronic disease. That urgency drives a practical roadmap for what to measure and why. You'll hear a clear breakdown of high‑value biomarkers—HbA1c for glucose trends, ApoB and the ApoB to ApoA1 ratio for cardiovascular risk, and thyroid markers for therapy tuning—and why total cholesterol alone often misleads. Tosh explains how accuracy is maintained through CLIA‑accredited labs and transparent methods, addressing trust in a post‑Theranos world. We also dig into biological age: how markers like hs‑CRP, HbA1c, and sex hormones push it up or down, and the specific lifestyle levers that can nudge it younger over the next 90 days.Then we open the hood on Sai, an AI longevity expert trained on a clinician‑curated knowledge base. Instead of scraping the noisy web, Sai reads your longitudinal labs, medications, and context to deliver personalized, evidence‑based guidance. Think trend detection for creeping glucose, stubborn ApoB, or hidden inflammation—and concrete next steps that you can take today. Looking ahead, Tosh shares what's next: home hardware that brings instant panels into your routine and a vision of predictive health where alerts trigger action long before symptoms do.If you want to cut through hype, track the markers that matter, and pair credible data with smart coaching, this conversation will give you the playbook. Subscribe, share with a friend who's optimizing their health, and leave a review with the one biomarker you plan to track this year.Note: I am an advisor to Siphox but I only advise those companies whose products I would use for myself and family.https://siphoxhealth.com/lufkinFASTING CHALLENGE: https://robert-lufkin.mykajabi.com/fast?ref=RLLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdSubstack: https://robertlufkinmd.substack.com Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...

Primal Potential
1375: Modern Anxiety, Digital Intrusion & the Chemistry of Peace

Primal Potential

Play Episode Listen Later Jan 3, 2026 23:43


Modern anxiety isn't just emotional. It's chemical — and it's being triggered and sustained by the way we're living, consuming, and overstimulating ourselves every single day. In this powerful, personal episode, Elizabeth pulls back the curtain on what's really happening when we feel anxious for "no reason" — and shares the neurochemical truth about dopamine, oxytocin, cortisol, and inflammation. If you're constantly in your head, overwhelmed, overstimulated, or one step away from panic — this conversation will shift everything. You'll also hear the exact strategy Elizabeth is using to reclaim peace and presence in her everyday life — without deleting her business, becoming a monk, or pretending life isn't loud and full.

The Keto Kamp Podcast With Ben Azadi
#1201 The Fastest Natural Way To Lower ApoB, CRP & Blood Pressure — No Meds Required with Ben Azadi

The Keto Kamp Podcast With Ben Azadi

Play Episode Listen Later Dec 30, 2025 19:28


In this episode, Ben Azadi reveals the real reason arteries clog and it's not age, genetics, or cholesterol. The true driver of heart disease is chronic inflammation and metabolic dysfunction. Ben breaks down five science-backed drinks proven in human studies to reduce arterial plaque, lower inflammation, improve insulin sensitivity, boost nitric oxide, and support long-term cardiovascular health. You'll learn how simple ingredients like pomegranate juice, high-quality coffee, raw cacao, apple cider vinegar, and turmeric can dramatically improve markers like ApoB, CRP, triglycerides, fasting insulin, and blood pressure. Ben also explains how to rotate these drinks for maximum benefit, which options are best for keto or diabetes, and how quickly you can expect to see results in your lab work. This episode empowers you with practical, natural tools your doctor likely never mentioned, helping you take control of your metabolic and heart health starting today. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat   - https://bit.ly/3L6xMo0 

The Trip Lab
#19 – DEEP DIVE SERIES: Hyperlipidemia (Why Cholesterol and Statins Aren't the Villains You Think They Are)

The Trip Lab

Play Episode Listen Later Dec 22, 2025 38:31


In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don't fit—within a thoughtful, individualized approach to cardiovascular risk.From there, we explore integrative strategies for managing elevated cholesterol and why, for many patients, lifestyle, metabolic health, and inflammation-targeted interventions may be more effective than medications alone.In this episode, we discuss:Why cholesterol is biologically essential and not inherently pathologicalThe limitations of relying on LDL alone to assess cardiovascular riskHow inflammation, insulin resistance, genetics, hormones, and lifestyle influence lipid metabolismWhen elevated cholesterol truly signals disease—and when it may reflect a compensatory or adaptive responseThe role of advanced markers such as ApoB, Lp(a), hsCRP and CAC scoresWhy risk stratification—not fear-based medicine—should guide clinical decision-makingWhat statins can (and cannot do) and we break down the concerns people have with themWhy integrative approaches (nutrition, exercise, herbal options and mind-body medicine) truly treat the root cause of diseaseThis episode is for clinicians, patients, and anyone looking to move beyond simplistic cholesterol narratives toward a more nuanced, evidence-based understanding of cardiovascular health.

ZOE Science & Nutrition
ZOE's best health tips of 2025 - Part 2

ZOE Science & Nutrition

Play Episode Listen Later Dec 18, 2025 48:29


Welcome to part two of our Best of 2025 series - the moments that changed how our listeners think about their health and what they do on a day-to-day basis. In this episode, we delve into simple questions with profound impact. Is it safe to experiment with your own health? Does cheese really cause bad dreams? Why do some breakfasts leave you tired and hungry, while others don't?  If you're looking for practical, science-led ideas you can take into the year ahead, this episode brings together the insights listeners found most useful, surprising, and worth returning to. Unwrap the truth about your food

The Peter Attia Drive
#376 - AMA #78: Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more

The Peter Attia Drive

Play Episode Listen Later Dec 15, 2025 22:17


View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter tackles a wide-ranging set of listener questions spanning lifespan interventions, exercise, cardiovascular risk reduction, time-restricted eating, blood pressure management, hormone therapy, diagnostics, and more. Peter reveals the single most important lever for extending healthspan and lifespan, and explains how he motivates midlife patients using the Centenarian Decathlon framework. He discusses the importance of addressing high apoB and cholesterol even in metabolically healthy individuals with calcium scores of zero, how to manage high blood pressure, and how to accurately evaluate metabolic health beyond HbA1c. Additional topics include time-restricted eating, practical considerations around ultra-processed foods, nuanced approaches to HRT for women and TRT for men, and why early and expanded screening for chronic disease—colonoscopy, PSA, coronary imaging, low-dose CT—can be lifesaving. He also offers insights into treating prediabetes, crafting exercise programs for those short on time, and safely incorporating high-intensity training in older adults. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #78 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Introducing a wide-ranging AMA: practical perspectives on lifespan interventions, metabolic health, diet, hormones, diagnostics, and more [2:45]; Why exercise is the most powerful single intervention for lifespan and healthspan [4:15]; How Peter motivates midlife patients to prioritize exercise [6:00]; Why lifespan and healthspan should not be treated as competing priorities and how choosing sustainable interventions benefits both [9:30]; Why high apoB deserves treatment even in a metabolically healthy patient with a CAC score of zero [14:00]; Managing hypertension: ideal targets for blood pressure, lifestyle levers, and why early pharmacology matters [18:15]; Assessing metabolic health beyond HbA1c: fasting insulin, triglycerides, lactate, zone 2, and more [23:30]; How to avoid common self-sabotaging patterns by choosing sustainable habits over extreme health interventions [26:00]; Time-restricted eating: minimal effect beyond calorie control, implications for protein intake, and practical considerations for implementing it [28:00]; Ultra-processed foods: definitions, real-world risks, and practical guidelines for smarter consumption [30:30]; How women should prepare for menopause and think about hormone replacement therapy: early planning, symptom awareness, and guidance on HRT [36:45]; Testosterone replacement for aging men: indications, benefits, and safe clinical management [39:45]; Why Peter recommends earlier and more aggressive screening tests than guidelines suggest: colonoscopies, coronary imaging, PSA, Lp(a), and low-dose CT scans, and more [43:30]; Full-body MRI screening: benefits, limitations, potential false positives, and the importance of physician oversight [47:15]; Prediabetes: individualized treatment strategies using tailored combinations of nutrition, sleep, and training interventions [51:00]; Time-efficient training plans for people with only 30 minutes per day to exercise [53:00]; How to safely introduce high-intensity exercise for older adults [55:00]; Timed dead hangs and ripping phone books: a playful look at Peter's early attempts to impress his wife [57:15]; Peter's carve out: The Four Kings documentary about a golden era of boxing [1:01:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

The Curbsiders Internal Medicine Podcast
#508: ASCVD Risk & Lipids Update! PREVENT, ApoB, Lp(a) + Next-Gen Therapies

The Curbsiders Internal Medicine Podcast

Play Episode Listen Later Dec 15, 2025 95:11


Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. We're joined by Dr. Laurence Sperling to break down what's new in ASCVD risk assessment and prevention. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments Intro Case 1 from Kashlak  Risk assessment framework ApoB and Non-HDL cholesterol Lipoprotein(a) and its importance The PREVENT risk score and its implications Statins and other lipid lowering therapies The role of diet and lifestyle in lipid management Case 2 from Kashlak Familial Hypercholesterolemia diagnosis and management Key takeaways Outro Credits Producer, Writer, Shownotes, Infographic, and Cover art: Ben Furman, MPH  Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Leah Witt, MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Laurence Sperling, MD  Disclosures Dr. Sperling reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. Sponsor: Bucksbaum-Siegler Institute If you want to learn more about what the Bucksbaum-Siegler Institute is doing and to nominate someone for the Clinical Excellence Award—you can check them out today. Visit bucksbauminstitute.uchicago.edu. Sponsor: Grammarly  Sign up for FREE and experience how Grammarly can elevate your professional writing from start to finish. Visit Grammarly.com/podcast.  Sponsor: Continuing Education Company Use promo code Curb30 to get 30% off all online courses and webcast. Visit CMEmeeting.org/curbsiders to learn more. Sponsor: Freed Use code: CURB50 to get $50 off your first month when you subscribe!

Creadores: Emprendimiento | Negocios Digitales | Inversiones | Optimización Humana
Cardiólogo: 5 Claves para Mantener un Corazón Saludable y Prevenir un Infarto

Creadores: Emprendimiento | Negocios Digitales | Inversiones | Optimización Humana

Play Episode Listen Later Dec 15, 2025 113:43


Dr. Carlos Hernández nos comparte 5 claves para mantener un corazón saludable y prevenir un infarto. Descubre cómo funciona el corazón y qué factores pueden llevarlo a enfermarse, así como las estrategias más efectivas para protegerlo y mantenerlo en óptimas condiciones.El Dr. Carlos Hernández desmitifica creencias comunes, como la idea de que el cardio es una pérdida de tiempo, y nos ofrece consejos prácticos para prevenir enfermedades cardiovasculares. Si estás interesado en cuidar tu corazón y mejorar tu salud cardiovascular, este episodio es una guía esencial.Show Notes(00:00) Intro: ¿El deporte extremo daña tu corazón? (02:39) Medicina Convencional vs. Medicina Funcional (El iceberg) (05:45) La epidemia silenciosa: Por qué los infartos empiezan a los 20 años (08:41) Anatomía 101: Cómo funciona la bomba cardíaca y el sistema vascular (13:02) Genética vs. Hábitos: ¿Estás condenado por tu herencia familiar? (16:22) Cómo saber si tienes un corazón sano (Señales visibles y funcionales) (19:50) La métrica reina: El VO2 Max y por qué la "normalidad" es estar enfermo (23:21) Los exámenes que tu médico NO te pide (ApoB, Lipoproteína A y Calcio Coronario) (32:01 ) ¿A qué edad deberías empezar a medirte? (La prevención real) (36:21) El peligro de la Lipoproteína (a) y el tabaco (39:11) La VERDAD sobre el Colesterol LDL: Mitos y realidades (43:00) Entendiendo la ApoB: La analogía de los "Barcos" y la carga (48:30) El Endotelio: La barrera que realmente protege tus arterias (53:01) ¿Insulina, Triglicéridos o Colesterol? Qué priorizar (56:22) Muerte súbita en atletas: ¿Por qué gente fit muere haciendo ejercicio? (59:15) El Estrés Crónico: El asesino invisible de emprendedores y creadores (1:05:03) ROMPEMITOS: Por qué la Obesidad y la Hipertensión son mecanismos de defensa (1:13:05) Cómo fortalecer el corazón: La dosis perfecta de ejercicio (1:18:30) Cardio vs. Pesas: El mix de longevidad para llegar bien a los 80 (1:25:22) Nutrición para el corazón: Qué comer y qué evitar (1:28:40) Suplementación clave: Omega 3 y Aceite de Oliva (1:31:21) Ritmos Circadianos: Dormir y vivir como humanos (1:35:01) Biohacking: Qué es la VFC (HRV) y cómo medir tu estrés (1:44:21) Cómo mejorar tu VO2 Max (Cardio aburrido + HIIT) (1:49:12) El mensaje final: De qué se arrepiente la gente antes de morir- Recibe 5% de descuento en tu suscripción de los mejores suplementos utilizando el código CREADORES en https://belevels.com/- Recibe acceso gratuito a mi lista de los 100 libros que transformarán tu vida aquí: https://www.creadores.co/newsletter- Únete a nuestra Escuela de Creadores, un programa de 12 semanas para transformar tu cuerpo, mente y negocios: https://creadores.co/escuela- Invierte en bienes raíces en EE. UU. con nosotros en Creadores Capital y genera retornos promedio del 20% anuales. Aplica aquí: https://www.creadorescapital.com/Invitado- Instagram: https://www.instagram.com/dr.carloshernandez1/- Sitio Web: https://www.doctorcarloshernandezmd.com/Creadores- Facebook: https://www.facebook.com/creadorespodcast- Instagram: https://www.instagram.com/creadorespodcast- Instagram: https://www.instagram.com/chelozegarra- TikTok: https://www.tiktok.com/@marcelozegarrac- Twitter: https://twitter.com/chelozegarrac- Email: https://www.creadores.co/contacto#CreadoresPodcast #CuidadoDelCorazón #SaludCardiaca #PrevenciónDeInfartos #ConsejosDeSalud

Everyday Wellness
Ep. 527 Ep. 527 HRT Changes Your Lipids More Than You Think – The Surprising Truth About Menopause & Heart Disease with Dr. Thomas Dayspring |Women's Cardiovascular Health

Everyday Wellness

Play Episode Listen Later Dec 10, 2025 58:07


I am honored to have Dr. Tom Dayspring join me again today for another AMA session. He and I have done eight podcasts before, and this is a continuation of our last Ask Me Anything episode.  Dr Dayspring is an esteemed expert on internal medicine and clinical lipidology. He is likely one of the most influential worldwide lipid experts, so I am thrilled to have him back with me to dive into various topics related to listener questions, including the impact of hormone replacement therapy on lipid changes, methods of administration, and why bioidentical hormone replacement therapy is preferable for managing both menopausal symptoms and lipid health. We discuss medications, including PCSK9 inhibitors and GLP-1s, as well as intermittent fasting, lipids, and cardiovascular disease risk. We also examine how heart disease develops gradually, over time, the impact of stress and lifestyle, and Dr. Dayspring shares the labs he recommends beyond traditional lipids, ApoB, and LpA. In our discussion, Dr. Dayspring noted that he was not in a position to speak about GLP-1 therapies or microdosing. Since I received many questions from listeners on those topics, I will host a future solo AMA to address some of their concerns. Today's conversation with Dr. Tom Dayspring is truly invaluable, and I trust you will walk away with valuable insights you can share with your healthcare providers. We created a PDF - cynthiathurlow.com/lipids -  specifically for listeners that outlines key labs to discuss with your providers and questions to ask them to help you advocate for your own health and your family members' health. IN THIS EPISODE, YOU WILL LEARN: Why being physically fit does not always eliminate the risk of heart problems arising How ApoB and cholesterol contribute to heart disease over decades Why the early testing of risk factors is essential How chronic stress increases the risk of heart disease  How high cortisol affects insulin sensitivity and glucose regulation How stress impacts endothelial and nitric oxide function The link between low Omega-3 levels and heart problems How insulin resistance degrades heart health How high homocysteine levels can impair endothelial function and contribute to cardiovascular problems Connect with Cynthia Thurlow   Follow on⁠ X⁠,⁠ Instagram⁠ &⁠ LinkedIn⁠ Check out Cynthia's⁠ website⁠ Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community ⁠(The Midlife Pause/Cynthia Thurlow⁠)⁠ ⁠ Cynthia's⁠ Menopause Gut Book⁠ is on presale now! Cynthia's⁠ Intermittent Fasting Transformation⁠ Book ⁠The Midlife Pause supplement line⁠ Connect with Dr. Thomas Dayspring On X (@DrLipid) On LinkedIn

Exam Room Nutrition: Nutrition Education for Health Professionals
137 | Cholesterol in the Brain: Connecting Heart Health and Alzheimer's

Exam Room Nutrition: Nutrition Education for Health Professionals

Play Episode Listen Later Dec 10, 2025 32:10


"What's good for the heart is good for the brain."  Can better cholesterol management in midlife actually lower your patient's risk of Alzheimer's disease? In this episode, I'm joined by returning guest Josh Wageman, PhD, PA-C, a clinical lipid specialist who studied cholesterol disturbances in Alzheimer's disease.  Together, we unpack how cholesterol, APOB, APOE4, insulin resistance, and statins intersect with Alzheimer's disease and cognitive decline, and what clinicians can do now to protect brain health long before symptoms appear. Plus, a peek at emerging therapies (including GLP-1 receptor agonists and lipid-centric approaches) and how a metabolic lens is reshaping future Alzheimer's treatment.Resources Mentioned:Josh's New Book117 | What's the Best Diet to Lower Cholesterol?111 | HDL = Good, LDL = Bad? It's Not That Simple.80 | The MIND Diet: What To Eat For Brain HealthAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week. Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

The Kirk Miller Podcast
E187 | 'The Truth About Biological Age and How to Reverse It' with Daniel Salewski‏

The Kirk Miller Podcast

Play Episode Listen Later Dec 8, 2025 54:15


In this episode of The Kirk Miller Podcast, Kirk sits down with Daniel Salewski—Founder and Director of Elite Vita—to explore the science and strategy behind extending not just lifespan, but health span: the years you live with vitality, clarity and peak performance. Daniel specialises in advanced DNA analysis, biomarker interpretation, and NAD-driven cellular optimisation, working with high performers who want to understand their bodies at a far deeper level than traditional healthcare ever allows. This conversation breaks down the real levers of longevity—rooted in data, not trends. In this episode, you'll learn: Why DNA testing + blood work is the new foundation of personalised health The difference between being in range and being optimal—and why most people settle for the former What NAD actually is, why levels drop with age, and how it impacts energy, recovery and brain performance The truth behind biological age vs chronological age—and how people are now reversing it How genetic variants affect nutrient absorption, inflammation, hormones, mood and more Why Vitamin D, APOB, CRP and other biomarkers predict disease risk long before symptoms show The order Daniel recommends for anyone serious about longevity: test first, then intervene Daniel also shares how Elite Vita is pioneering a more personalised approach to healthcare—moving away from guesswork and towards precision-led protocols tailored to each individual's biology. If you're a business leader, entrepreneur or high performer who wants more energy, better health and a longer runway to operate at your best, this episode will give you clarity on what to do next—and what to ignore. For more information on what was discussed in this episode head to https://kirkmiller.co.uk/programme/ The Kirk Miller Podcast is the show for business leaders and peak performers to get into the best physical and mental shape of their lives and unleash from within confidence they never thought possible.

The Knew Method by Dr.E
Heart Attacks with “Normal” Cholesterol? A Functional Cardiologist Explains

The Knew Method by Dr.E

Play Episode Listen Later Dec 2, 2025 59:29


Heart attacks in people with “normal” cholesterol are not rare outliers. They're the warning flare that our entire playbook is broken. In this episode of Medical Disruptors, I sit down with interventional cardiologist-turned-functional cardiologist Dr. Sanjay Bhojraj to unpack what happens when you do everything “right” on paper… and still end up in the ER with a heart attack. We get into advanced lipid testing (ApoB, Lp(a), and small dense LDL) and how different LDL particle patterns can drive very different levels of plaque risk. We also break down how standard stress tests miss the very plaques that actually rupture, and why CTA and smarter labs are finally giving us a way to see real cardiovascular risk. Your labs, your lifestyle, your environment, and your nervous system all matter—and you deserve a plan that reflects that. Hit play and start upgrading how you think about your heart. Looking to schedule a consultation with Dr. E? Book here: drefratlamandre.com/consult Check us out on social media: drefratlamandre.com/instagram drefratlamandre.com/facebook drefratlamandre.com/tiktok #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters [00:00:00] Introductions and background [00:04:31] Eight-heart-attack weekend [00:06:53] Discovering functional medicine [00:27:38] Advanced cholesterol labs [00:49:34] Programs and next steps Guest Links: FB: @doctorsanjaymd IG: @doctorsanjaymd YT: @doctorsanjaymd Website: www.lagunamedicne.com Learn more about your ad choices. Visit megaphone.fm/adchoices

The Keto Kamp Podcast With Ben Azadi
#1169 The 5 Powerful Drinks Proven to Clear Arteries, Lower Inflammation, and Supercharge Metabolic Health… Naturally and Fast — With Ben Azadi

The Keto Kamp Podcast With Ben Azadi

Play Episode Listen Later Nov 28, 2025 19:29


In this episode, Ben Azadi breaks down five science-backed metabolic drinks that naturally reduce arterial plaque, boost nitric oxide, lower inflammation, and support metabolic health — without medications or side effects. You'll learn: • Why arterial inflammation — not cholesterol — is the real silent killer• How pomegranate juice reversed arterial plaque by 30% in human studies• The surprising cardiovascular benefits of high-quality coffee with butter, olive oil, and salt• Why raw cacao improves arterial flexibility by up to 400% (Harvard study)• How apple cider vinegar and cinnamon lower fasting glucose, HbA1c, and triglycerides• The anti-inflammatory power of turmeric + black pepper and how it calms the arteries Ben also explains:• Which drink is best for diabetics• How to rotate the drinks weekly for maximum benefit• What markers to test before and after 30 days to measure progress (ApoB, CRP, fasting insulin, triglycerides, HDL, CAC score, and more) Plus, he shares a free guide revealing the five vegetables silently inflaming your gut and slowing your metabolism — and what to eat instead. A simple daily cup could dramatically upgrade your cardiovascular and metabolic health. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat - https://bit.ly/48CIprn

Wits & Weights: Strength and Nutrition for Skeptics
A Cardiologist's Guide to Hormones, Peptides, and Labs for Lifters Over 40 (Dr. Abid Husain) | Ep 406

Wits & Weights: Strength and Nutrition for Skeptics

Play Episode Listen Later Nov 28, 2025 64:27 Transcription Available


Ready to go beyond standard cholesterol panels and track what actually matters? Get your comprehensive performance bloodwork analysis at  witsandweights.com/bloodwork (code VITALITY20 for 20% off)—What if your blood work is missing the markers that truly predict long-term cardiovascular health? Can you build muscle, lose fat, and stay strong after 40 without risking your heart? And which biomarkers, hormones, and peptides actually move the needle for longevity and performance?I bring on Integrative Medicine & Cardiology Physician Dr. Abid Husain into the conversation, and we get into the evidence behind cardiovascular health for lifters, especially if you're focused on body recomp, strength training, weight loss, nutrition, and fitness. We cover the labs most people never get, how inflammation and metabolism shape heart health, and why tracking APOB, CRP, and oxidized LDL matters far more than total cholesterol. We also break down hormone health, HRT safety, muscle building over 40, and the peptides that actually support recovery and longevity.If you care about lifting weights, performance, and living longer with evidence-based fitness, this one gives you a clear roadmap. Tune in to learn more.Today, you'll learn all about:0:00 – Defining cardiovascular health3:40 – Mechanical vs biochemical heart health7:42 – Obesity, genetics, and heart disease12:10 – Key biomarkers to track18:55 – Inflammation patterns and risk23:20 – Cholesterol, genetics, and LDL nuance28:40 – Hormone health and HRT safety35:20 – Peptides for recovery and performance49:55 – Calcium scoring vs CCTA imaging*Episode resources:*Website: boulderlongevity.com Dr. Abid Husain's Instagram: @dr_abidhusain Boulder Longevity Institute's Instagram: @boulderlongevityinstitute LinkedIn: linkedin.com/in/abid-husain-md-facc-abaarm-00874419 YouTube: @boulderlongevityinstitute Facebook: @BoulderLongevityInstitute Support the show

The Vibrant Wellness Podcast
Optimal Heart Health Through Lifestyle, Labs & Mindset with Dr. Jack Wolfson, DO

The Vibrant Wellness Podcast

Play Episode Listen Later Nov 26, 2025 53:32


“Cardiologist Dr. Jack Wolfson reveals the true root causes of heart disease — and why it's far more preventable than you've been told.”Dr. Brooke Stubbs sits down with cardiologist Dr. Jack Wolfson to uncover the real causes of heart disease beyond cholesterol. They discuss toxins, inflammation, gut health, mindset, lifestyle, and the advanced labs that actually matter. Dr. Wolfson also shares why he left conventional cardiology and why he believes heart disease is 100% preventable. A must-listen for anyone ready to take control of their cardiovascular health naturally.⭐ What You'll Learn• Why Dr. Wolfson left the hospital system to pursue preventative, natural care• How toxins, environment, and daily habits trigger heart disease• Why nutrition & organic living matter more than pharmaceuticals• What labs actually predict cardiovascular risk (ApoB, oxidized LDL, inflammation markers, intracellular nutrients)• How gut permeability (“leaky gut”) connects to plaque and inflammation• Circadian rhythm, sleep, sunlight & nervous system health• The truth about stress, relationships, trauma & heart attacks• Why Wolfson says 100% of heart disease is preventable• Parenting, homeschooling, and raising healthy families

The Cabral Concept
3581: How to Lower Dangerous ApoB Cholesterol Naturally (TWT)

The Cabral Concept

Play Episode Listen Later Nov 25, 2025 16:14


Most people assume that normal cholesterol means a healthy heart, but that isn't always the case...     On today's show, we dive into why Apolipoprotein B (ApoB) is one of the most important yet overlooked markers for assessing true cardiovascular risk.     You'll learn why ApoB can reveal hidden plaque formation even when LDL appears normal, the ideal range to aim for, and why inflammation and metabolic health often matter more than total cholesterol alone.     We'll also explore the deeper factors that influence heart health, including insulin resistance, thyroid function, gut permeability, hormonal changes, diet, stress, and sleep.      Join me on today's Cabral Concept 3581 to discover what your cholesterol panel may be missing and how to take a more accurate, proactive approach to protecting your heart.     Enjoy the show!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3581 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

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PVRoundup Podcast
How much can staying active in adulthood realy cut dementia risk?

PVRoundup Podcast

Play Episode Listen Later Nov 25, 2025 5:41


A long-term Framingham Heart Study analysis shows that regular physical activity beginning in midlife and continuing into older age significantly lowers the risk of dementia, including Alzheimer disease, with the most active individuals experiencing roughly 40–45% risk reduction. A phase 3 trial of the first oral PCSK9 inhibitor, enlicitide, demonstrated substantial LDL-C and apoB reductions in patients with heterozygous familial hypercholesterolemia already on statins, offering a well-tolerated oral option that helps most patients reach guideline targets. Finally, a large U.S. cohort study revealed persistent under-treatment of chronic hepatitis B—especially among women and non-Asian racial groups—highlighting the need for standardized assessment and timely antiviral therapy to close these gaps.

Wild Health
497 | Dr. Damon Forbes | Understanding Lipoprotein(a) and Cardiovascular Risk

Wild Health

Play Episode Listen Later Nov 19, 2025 51:43


Dr. Erin Faules speaks with Dr. Damon Forbes about Lp(a), a genetically influenced lipoprotein linked to cardiovascular disease risk. They discuss how Lp(a) differs from LDL, its role in plaque and clotting, and why a one-time test can help clarify long-term risk. The conversation covers who to screen and when, interpreting Lp(a) alongside apoB and metabolic health, evidence-based ways to lower overall cardiovascular risk, and emerging Lp(a)-lowering therapies

GRUFFtalk How to Age Better with Barbara Hannah Grufferman
Replay: Lp(a) – The Heart Test You Need Now with Dr. Ann Marie Navar EP 176

GRUFFtalk How to Age Better with Barbara Hannah Grufferman

Play Episode Listen Later Nov 18, 2025 35:08


“I think everyone should have Lp(a) measured.”  - Dr. Ann Marie Navar   Key Resources to Go Deeper:  - Dr. Ann Marie Navar  - Lp(a)  - Get a Free Test to Check Your Lp(a) Level   - Previous episode with Dr. Navar about ApoB  About This Episode:  Listen to this replay of an important discussion about Lipoprotein(a), or Lp(a), a critical but often overlooked marker for cardiovascular health. In this episode, host Barbara Hannah Grufferman takes a deep dive with medical expert Dr. Ann Marie Navar from UT Southwestern Medical Center about why this single test could be vital for understanding your heart disease risk, especially if you have a family history of early cardiovascular disease.  Key Topics Covered:  - What Lipoprotein(a) is and how it differs from standard cholesterol measurements  - Why Lp(a) testing is particularly important for certain individuals  - The genetic nature of Lp(a) and its implications for family health  - Current treatment options and promising new therapies on the horizon  - Practical steps for discussing Lp(a) testing with your healthcare provider  Key Takeaways:  - Lp(a) is a distinct type of cholesterol particle not captured in routine lipid panels  - High Lp(a) levels significantly increase risk of heart disease and stroke  - Lp(a) levels are primarily determined by genetics and remain stable throughout life  - Current guidelines recommend universal Lp(a) testing for adults  - New treatments specifically targeting high Lp(a) levels are expected by 2026  - Managing other risk factors can help offset the risk of elevated Lp(a)  - Coronary artery calcium scoring can provide additional risk assessment  Learn More About Dr. Ann Marie Navar  Dr. Navar is a preventive cardiologist and epidemiologist at UT Southwestern Medical Center whose research focuses on cardiovascular disease prevention, risk prediction, and clinical decision-making. She is a leading expert in advanced lipid testing and cardiovascular risk assessment. This is Dr. Navar's second appearance on AGE BETTER, following her previous discussion about the ApoB test, which was one of the most down-loaded episodes in 2024.   Connect With Barbara:  Have ideas for future episodes? We'd love to hear from you!  - Email: agebetterpodcast@gmail.com  - Connect on Instagram HERE  Note: This episode is for informational purposes only and does not constitute medical advice. Please consult with your healthcare provider about your specific situation. Learn more about your ad choices. Visit megaphone.fm/adchoices

The mindbodygreen Podcast
624: VO2 max, wearables, & eliminating heart disease risk | Peter Attia, M.D.

The mindbodygreen Podcast

Play Episode Listen Later Nov 16, 2025 52:44


“VO2 max is the best predictor of lifespan,” says Peter Attia, M.D. Peter Attia, M.D., physician, founder of Early Medical, and expert in the applied science of longevity, joins us today to break down the key levers for extending both lifespan and healthspan—from how to train for a higher VO2 max to the biomarkers that truly predict long-term health. - The most powerful habit for longevity (~6:15) - VO2 max (~8:55) - How to increase your VO2 max (~10:08) - Heart rate vs. perceived exertion (~12:35) - Attia's strength training routine (~15:20) - 2 exercises Attia stopped doing (17:00) - Diminishing returns in terms of exercise (~19:55) - His take on wearables (~21:25) - Cardiovascular disease markers (~23:38) - Lowering ApoB (~25:35) - Pharmaceutical interventions for LDL & ApoB (~27:50) - Neuroinflammation markers (~37:25) - Perspectives on statins (~40:45) - The role of nutrition (~42:50) - Potential benefits of GLP-1s (~45:00) - Peptides (~47:50) - The power of exercise (~51:00) Referenced in the episode:  - Follow Attia on Instagram (@peterattiamd) - Listen to his podcast, The Peter Attia Drive  - Check out his website (https://peterattiamd.com/)  - Pick up his book, Outlive: The Science of Art & Longevity  - Take his class on MasterClass (https://www.masterclass.com/series/science-for-a-longer-better-life) - Watch the trailer for his class on MasterClass (youtube.com/watch?v=f_Mz095swls&feature=youtu.be)   We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Everyday Wellness
Ep. 517 The Hidden Heart Risks No One Talks About – A Masterclass on Women's Cardiovascular Health

Everyday Wellness

Play Episode Listen Later Nov 12, 2025 46:33


I'm excited to share a new AMA episode with you today, dedicated to risk factors specific to women. In this AMA session, I dive into the lifestyle factors that influence lipids, exploring the latest research and discussing Lp(a) and ApoB. Rather than answering your individual questions, I have woven them into the overall outline to create a cohesive and informative conversation. IN THIS EPISODE, YOU WILL LEARN: How women's lifestyle choices directly affect their lipid profiles How knowing if you're a hyper absorber or hyper producer of cholesterol will change your treatment strategy What the Boston Heart Cholesterol Balance test will reveal about your body's ability to handle cholesterol The best treatments for hyper absorbers, and the best treatments for hyper producers How hard plaque differs from soft plaque, and why that matters for women's heart health How the new AI-assisted Clearly scan provides a more complete cardiovascular risk picture than a standard calcium score How chronic stress and elevated cortisol fuel insulin resistance and inflammation, and damage blood vessel linings The benefits of Mediterranean-style eating for improving lipid balance, vasomotor symptoms, and overall metabolic health The importance of managing trauma, stress, and emotional health in midlife How my “n=1” experiment with Zetia and micro-dosed GLP-1s significantly improved my ApoB and inflammation markers Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Resources:  Dietary natural products as emerging lipoprotein(a)-lowering agents The Effects of Menopause Hormone Therapy on Lipid Profile in Postmenopausal Women: A Systematic Review and Meta-Analysis An Update on Lipoprotein(a): The Latest on Testing, Treatment, and Guideline Recommendations

The Neuro Experience
This Everyday Food Could Save Your Heart | ft. Dr. Rupy Aujla

The Neuro Experience

Play Episode Listen Later Oct 30, 2025 11:32


I used to think of fiber as just “good for digestion,” but it turns out this single nutrient can lower cholesterol as powerfully as a statin—and do so much more for your brain, gut, and longevity. In this minisode of The Neuro Experience, I sit down with Dr. Rupy Aujla — NHS doctor, author, and founder of The Doctor's Kitchen — to break down the science behind fiber and why it's one of the most underrated tools for preventing heart disease and inflammation. This episode features highlights from our full conversation, which premiered August 5th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=Jay-Sg2sg6s Connect with Dr. Rupy Aujla: Website: The Doctor's Kitchen Instagram: @doctors_kitchen Books: The Doctor's Kitchen & Eat to Beat Illness *** Topics discussed: 00:18 – The TikTok “fiber maxxing” trend explained 00:42 – How to transition from low-fiber to high-fiber safely 01:02 – How fiber binds cholesterol and removes it from the body 01:26 – Feeding your gut microbes: the real reason fiber matters 02:10 – What short-chain fatty acids do for inflammation and longevity 03:00 – How fiber increases LDL receptor activity in the liver 03:42 – How 60 days of high-fiber eating lowers ApoB and LDL 04:03 – The “Portfolio Diet” that rivals statins 05:08 – The best fiber-rich foods: oats, barley, soy, nuts, seeds 06:14 – What to know about oats, glyphosate, and processing 07:16 – The perfect high-fiber breakfast recipe 07:53 – How food can match statin effects (and go beyond) 09:10 – The one daily change to reduce heart attack and stroke risk 09:26 – Dr. Rupy's B.B.G.S. formula for everyday health 10:13 – How fiber diversity transforms cholesterol and gut health *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Intelligent Medicine
Q&A with Leyla, Part 2: Whole-Body Scans

Intelligent Medicine

Play Episode Listen Later Oct 30, 2025 41:17


Boundless Body Radio
Cholesterol and Mental Health with Returning Guest Dr. Josh Wageman! 893

Boundless Body Radio

Play Episode Listen Later Oct 29, 2025 62:26


Send us a textJosh Wageman is a returning guest on our show! Be sure to check out his first appearance on episode on 869 of BBR!Josh Wageman is a Clinical Lipid Specialist with multiple doctoral degrees who formerly practiced in Endocrinology. His PhD work focused on cholesterol disturbances in Alzheimer's Disease and, although he also has a Doctorate in Physical Therapy, he is best known for his role in teaching lipid physiology.He serves as an adjunct professor at several medical programs and his goal is to help you, whoever you are, NOT have heart attacks, strokes, and dementia by explaining complicated biochemical concepts in a relatable way!Employing a smorgasbord of metaphors, pictures, and catchphrases, his latest book The Home Security System and the Lipid Neighborhood serves as a valuable reference for clinicians and non-clinicians alike, bringing refreshing relatability to complex biochemical topics. Through a lipid-lens, you'll learn, laugh, and love your way through its pages…and in the end, you'll undoubtedly add “life to your years!”Josh is active in Youth Ministries at Heritage Bible Church in Boise, Idaho, and resides there with his family. He also enjoys Crossfit, basketball, Ultimate Frisbee, and all sports that don't involve skates.Find Dr. Wageman at-Amazon- The Home Security System and the Lipid Neighborhood IG- @wagemanjoshLK- @Josh WagemanFind Boundless Body at- myboundlessbody.com Book a session with us here!