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Ep 127: Today I'm joined by board-certified neurological surgeon and regenerative medicine specialist Dr. Jeff Gross to talk about what exists between traditional physical therapy and surgery. We break down peptides and exosomes, what treatments like BPC-157 are actually being used for, and what to look out for in order to make sure the treatments you're receiving are legitimate.We also talk about how long the benefits of these therapies may last, what happens when you stop using them, and why maintaining muscle and strength remains one of the most important pieces of protecting our health and function as we age.Book a free 30 min consultation with Dr Jeff Gross here.Explore his instagram here. ____________________________Apply for Advanced Training and Nutrition with Chelsey & Dr Emily Dow HEREStart your 7 day FREE trial of my new app HERE!**Programs:8 Week Summer Prep Planhttps://www.trainerize.me/profile/chelseyrosehealth/?planGUID=d48c6fbf116c4e8fb4d31f94b5376fa34 Week Busy Body Plan (40 min at home workouts)https://www.trainerize.me/checkout/chelseyrosehealth/Chelsey.Rose?planGUID=524796f40f0a427fb25f03f4885972a0**Want to work one on one with Chelsey?Set up a one on one consultation call here to see if personalized online training is right for you.Join a semi-private class in LA here.Email info@chelseyrosehealth.com to inquire about one on one in person training.**Shop the things i'm loving HERE**Follow Chelsey on Instagram:@Chelseyrosehealth@StrengthtobuildFollow Chelsey on TikTok Here."Submit a question to the show"
Apply to work with the MI team → https://muscleintelligence.com/apply Ryan Smith co-founded the first pharmacy in the United States to offer an extensive list of peptides — and he ran the synthesis floor himself. Preparative HPLC, mass spec, chemical synthesis, the lot. Which means he spent years watching the same two failures from the inside: the molecule that works beautifully at a small dose and stops working when someone doubles it, and the vial that looks identical to the real thing and isn't. He is not a peptide evangelist. Ask him about the compound he calls ten million times more potent than BDNF and he'll tell you why he doesn't take it. His argument here is quieter than most of what gets said about peptides, and harder to unhear afterward: the body is already a competent system, and nearly everything that goes wrong with these compounds comes from handing it more input than it needed. Why exogenous growth hormone removes a brake the secretagogues leave in place. Why ipamorelin became the standard despite releasing less growth hormone than the compounds it replaced. Why two vials of the same peptide, at the same purity, can behave completely differently. He would rather talk about what he refuses to make than what he's excited about — and by the end of the hour it's clear those are the same conversation. 5 Key Takeaways Why exogenous growth hormone removes a brake your body doesn't get back — and what CJC-1295, ipamorelin and tesamorelin do instead The reason ipamorelin became the clinical standard despite releasing less growth hormone than the compounds it replaced Why the same 500-microgram dose of oral BPC-157 works in one form and barely at all in another Why the peptide he calls 10 million times more potent than BDNF is the one he leaves out of his own stack What a clean HPLC mass spec report still can't tell you about what's in the vial — and why that one blind spot lands on your liver Chapters 0:00 Why Peptides Took a Century to Arrive 4:54 Specificity, Growth Hormone & the Scalpel Argument 16:22 Thymosin Alpha-1, Epitalon & Natural Testosterone 25:25 Mitochondrial Peptides & the Fat Loss Compounds 32:27 BPC-157: Repair, Dosing & the Salt Form Problem 35:46 Peptides for the Brain: FGL, Dihexa & Cerebrolysin 47:05 What He Takes, What He Refuses & Why 52:36 Side Effects, Purity & What's Really in the Vial Connect with Ryan X – https://x.com/ryansmithepiage LinkedIn – https://www.linkedin.com/in/ryan-smith-lexington-ky/ TruDiagnostic – https://www.trudiagnostic.com
Peptides are everywhere—but what's actually safe, what's a scam, and what should you avoid?Sidney Gordon breaks down the peptide industry, including BPC-157, TB-500, black-market peptides, blood work, third-party testing, and the biggest red flags to watch for.If you're using peptides or thinking about starting, educate yourself before putting anything into your body.
In this episode, Dr. Rena Malik, MD explores the evolving landscape of anabolic peptides and their impact on men's health, hormone optimization, and overall well-being. Joined by Dr. Mohit Khera, Dr. Kevin Campbell, and Dr. Alex Tatem, the discussion unpacks what peptides are, the challenges of regulation and safety, and the latest research on compounds like BPC-157, CJC-1295, and GLP-1s. Listeners will gain data-driven insights on navigating the peptide craze safely, understanding true health optimization, and making informed decisions in a rapidly changing market. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00:00 Introduction00:02:46 What Peptides Actually Are00:04:09 Why Peptides Became So Controversial00:10:34 Compounding Pharmacies vs Research-Use Peptides00:13:31 Peptides That Raise Safety Concerns00:22:58 Growth Hormone Peptides and Sleep Claims00:28:01 PT-141 and Sexual Function00:44:45 GLP-1s, Testosterone, and Muscle Loss00:58:58 What Peptide Research Should Study Next Stay connected with Dr. Mohit Khera, Dr. Kevin Campbell, and Dr. Alex Tatem on social media for daily insights and updates. Don't miss out—follow them now and check out these links! Dr. Mohit Khera INSTAGRAM - https://www.instagram.com/drmohitkhera/?hl=en X - https://x.com/DrMohitKher WEBSITE - https://drmohitkhera.com/ Dr. Kevin Campbell X - https://x.com/KJCampbellMD Dr. Alex Tatem INSTAGRAM - https://www.instagram.com/dralextatem/?hl=en YOUTUBE - https://www.youtube.com/@DrAlexTatem TIKTOK - https://www.tiktok.com/@dr..alex.tatem X - https://x.com/DrAlexTatem WEBSITE - https://dralextatem.com/ Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices
We're back for a special Togethermess Episode 271 with Trevor Kruder, founder and CEO of Paramount Health RX and Alpha Biomed Industries, to ask all the peptide questions Jeff has been saving up for years.We talk GLP-1s, injury recovery, weight loss, BPC-157, peptide safety, cancer questions, shots vs. pills, and why this world feels so confusing. This is not medical advice, just our conversation.Our official Jeff and Jordan merch shop is now open!Visit https://togethermess.com/ to shop TogetherMess merch, favorite finds, videos, family stories, and a little everyday chaos.Thank you to our partners:Tumble - Get 10% off plus free shipping at https://tumbleliving.com/togethermess. Machine-washable rugs made better. After you purchase, please support the show and tell them TogetherMess sent you.Hungryroot - For a limited time, get 40% off your first order PLUS a free item in every box for life. Go to https://hungryroot.com/togethermess and use code togethermess. Simplify back-to-school meals with easy recipes, quality ingredients, and groceries delivered to your door.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Book a free call with Robert Sikes to break through your keto or low-carb plateau: https://www.ketobodybuilding.com/callDoes muscle matter more than costly biohacks for longevity and health? In episode 910 of the Savage Perspective Podcast, host Robert Sikes sits down with sports medicine doctor Dr. Jordan Metzl to expose the truth about peptides, BPC-157, GLP-1 drugs, supplements, and quick fixes. They explain why movement, strength training, real food, sleep, purpose, and community matter more for health span than wellness trends. Learn how muscle helps metabolism, blood sugar, brain health, mobility, and healthy aging. He also explains why motivation fades, how to make habits last, what changes after age 50, and why fast-twitch muscle matters. This episode gives clear steps to stay strong and active for decades.Follow Jordan on IG: https://www.instagram.com/drjordanmetzlGet Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - Why Most Longevity Biohacks Miss What Actually Works2:38 - Why Expensive Biohacks Cannot Replace the Basics5:02 - Are GLP-1 Drugs Becoming the New Health Shortcut?5:43 - Why Medical Trust Collapsed After the Pandemic7:07 - What Does Healthy Longevity Really Mean?8:25 - Why Exercise Should Be Prescribed Like Medicine9:51 - What Is the Science of Motivation? Dr. Jordan Metzl's Push10:44 - How One Woman Ran 15 Marathons After Starting at 6912:44 - Why Some People Stay Motivated for Life14:04 - What Does "Lowering the Cost to Act" Mean?15:45 - Do Consequences Make Fitness Habits Stick?16:58 - Can You Start Powerlifting at 59 and Set Records at 70?17:29 - What Is Muscle Span and Why Does It Matter?18:50 - Is More Muscle Always Better for Longevity?20:48 - Why Everyone Should Think Like a Bodybuilder23:53 - Does Metabolism Really Slow Down With Age?25:21 - How Strength Training Changes Metabolism After 6527:06 - Why Consistency Beats the Perfect Fitness Plan28:18 - Why Your Fitness Goal Must Be Bigger Than You29:03 - What Blue Zones Teach Us About Purpose and Longevity30:48 - How Family and Purpose Change the Way We Age32:18 - Why Social Wellness Matters as Much as Physical Health33:39 - Is Constant Stimulation Damaging Our Health?34:40 - How to Find Calm in an Overstimulated World35:46 - What Are the Most Common Sports Injuries?37:30 - Why You Never Appreciate Mobility Until It Is Gone39:14 - Do Injuries Come From Overtraining or Inactivity?41:10 - How to Preserve Fast-Twitch Muscle After Your Mid-30s42:12 - Does BPC-157 Work for Injury Recovery?44:25 - Functional Medicine, AI and the Limits of Health Advice46:22 - Why Experts Are Building Private AI Knowledge Bases47:19 - Why the Wellness Industry Is Harder to Trust Than Ever48:21 - Why More Health Information Has Not Made Us Healthier49:25 - How Dr. Jordan Metzl Structures His Day for Long-Term Fitness50:24 - Inside Dr. Metzl's 1,000-Person Fitness Community51:53 - Where to Find Dr. Jordan Metzl
What if the pursuit of optimal health is actually making health more complicated than it needs to be?Dr. Jordan Feigenbaum is a physician, competitive strength athlete, coach, and co-founder of Barbell Medicine, where he works to bridge the gap between modern medicine, strength training, and evidence-based health.In this episode, Bryce sits down with Jordan for a wide-ranging conversation about one of the strangest moments in modern wellness.Peptides. Biohacking. Testosterone. GLP-1s. Protein. Pain. Strength. Recovery. Longevity. Health optimization.We have more information, testing, supplements, technology, and “hacks” than ever before…but are we actually getting healthier?Jordan challenges some of the health and fitness beliefs we've accepted as fact and explains why evidence matters, why our bodies may be more resilient than we think, and why getting stronger might still be one of the most powerful health interventions available to us.This isn't about rejecting innovation.It's about learning to separate evidence from enthusiasm.MAJOR TAKEAWAYS• Not all “peptides” are the same. Some peptide medications have strong evidence behind them, while many compounds promoted by biohacking and longevity clinics have little or no quality human evidence.• Biological plausibility isn't the same thing as proof. Something sounding like it should work doesn't mean we've demonstrated that it does.• More health data doesn't automatically create better health.• Strength training remains one of the most accessible and powerful tools we have for improving health, physical capacity, and quality of life.• Pain doesn't always mean damage, and treating the human body as fragile can change how people move, train, and see themselves.• Health shouldn't become an endless pursuit of optimization.• Before searching for the next compound, supplement, wearable, or hack, ask whether you've mastered the fundamentals.• Good science requires being willing to change your mind when better evidence arrives.QUESTIONS WE EXPLOREWhy have peptides exploded in popularity?Are compounds like BPC-157 being promoted faster than the science supports?Have longevity clinics blurred the line between medicine and marketing?When does biohacking become health anxiety?Are we overtesting hormones and testosterone?Are GLP-1 medications fundamentally different from the broader peptide craze?Does pain actually mean your body is damaged?Do we overcomplicate mobility and recovery?How important is strength for longevity?And ultimately…Have we become so obsessed with optimizing health that we've forgotten how to simply be healthy?QUOTES“Evidence and enthusiasm are not the same thing.”“Your body is probably more resilient than you've been taught to believe.”“More information doesn't always create better decisions.”“Before you optimize everything, make sure you've mastered something.”“Health should give you more freedom to live, not more things to worry about.”TIMESTAMPS00:00 – Welcome to ALLSMITH00:00 – Meet Dr. Jordan Feigenbaum00:00 – Medicine meets the barbell00:00 – Why Jordan questions conventional health advice00:00 – The explosion of peptides00:00 – BPC-157 and the evidence problem00:00 – Peptides vs. proven medications00:00 – Has biohacking gone too far?00:00 – Testosterone, hormones & optimization00:00 – GLP-1s, obesity & modern medicine00:00 – Protein myths and nutrition00:00 – Pain doesn't always mean damage00:00 – Are our bodies more resilient than we think?00:00 – Mobility, stretching & recovery00:00 – Strength training as medicine00:00 – What actually matters for longevity?00:00 – Health anxiety and wearable data00:00 – Evidence vs. wellness marketing00:00 – The fundamentals we keep ignoring00:00 – Jordan's non-negotiables for lifelong healthCONCLUSIONThe future of health will undoubtedly bring better technology, medications, diagnostics, and tools.But new doesn't automatically mean better.Jordan's work is a reminder to stay curious without becoming gullible, to question conventional wisdom without rejecting science, and to demand evidence before allowing hype to dictate how we treat our bodies.Maybe the ultimate health hack isn't another injection, supplement, wearable, or protocol.Maybe it's building a strong body, thinking critically, staying connected to people you love, and creating a life you're healthy enough to actually enjoy.JOIN ALLSMITHIf this conversation challenged something you believed, send it to someone who would enjoy wrestling with these ideas too.Subscribe to ALLSMITH on YouTube and follow the show on Apple Podcasts and Spotify.If the show brings value to your life, leaving a rating or review is one of the simplest ways you can help us continue bringing these conversations to more people.Fitness is the vessel. Life is the upgrade.Welcome to ALLSMITH.Thank you for Listening! Learn more below.ALLSMITH IG ALLSMITH YouTubeBryce Smith IG
Not yet a member? Ad-free listening, the Discourse community, and a members' show every week, all for less than you spend on gels.Show notesOn the show this week, a European Championships wrap featuring Nadia Battocletti's astonishing 10,000m finish and Audrey Werro's win over Keely Hodgkinson, a German sprinter under a doping cloud, world records in the pool, and a follow-up on peptides.(00:01:41) A follow-up to the peptides show with Mike, and the thing Ross wishes he had said. The anecdote that BPC-157 failed to fix someone's Achilles is the human version of publication bias, because nobody ever tells you about the thing that didn't work.(00:12:23) The European Championships format and the broadcast, which featured more talking heads than athletics on the BBC, and an athletic programme with far too little action relative to downtime.(00:16:52) The women's 800m, where Werro beat Hodgkinson for her fourth sub-1:55 of the year, and Bol ran a national record in third. Whose trajectory looks best in the medium to long-term?(00:28:26) Batocletti's exceptional sprint finish, and a Tim Noakes tweet asking why she could speed up at all. Ross explains the end spurt, the reserve we all hold back, and why this particular race proves rather less than it appears to.(00:31:52) A stat from Jason Henderson: Batocletti's last 200m was 28.17, Werro's in the 800m was 29.11. Not a typo, and we explain why the fatigue of an 800m is a completely different animal, and speculate that it's probably more common than you'd think for the 10000m races to finish faster than the 800m ones(00:34:37) Andreas Almgren's solo 10,000m, run at 26:43 pace for the final 8.8km. Tactical optimization and a signal for a sub 26:30 in the future?(00:40:22) Amy Hunt's four golds, and a newspaper headline that poured cold water on them.(00:43:42) Owen Ansah wins European gold under a doping cloud, having refused a test because he had a flight to catch. What counts as "compelling justification", and why a 2016 case suggests he is in trouble.(00:52:26) The tragic death of Fin Tarling, the near-impossibility of policing a 1,300km course, and Adam Hansen's call for better helmets, which are certified only to 19.5km/h.(00:59:47) Swimming, where Kate Douglass broke the 50m freestyle world record twice in a day, a 19-year-old German went under 14:30 for the 1500m free, and Lani Pallister beat Katie Ledecky over 800m for the first time.(01:10:46) And finally, South Africa versus New Zealand has branded itself "Rugby's Greatest Rivalry". Gareth is not buying it. Ross offers the context for why it's about more than rugby, but also great rugbyNo news show next week, but there's an interview show planned for Monday, and the members' Applied show will take overtraining next week Friday. Hosted on Acast. See acast.com/privacy for more information.
Fascia, cadaver labs, iron and ferritin, red light therapy marketing, peptides, and total plasma exchange (TPE) — Freddie sits down with functional health practitioner Lauren Sambataro of the BioHacker Babes for a wide-ranging conversation on why more health data and more powerful interventions haven't translated into better health outcomes. Freddie and Lauren dig into the difference between context and content — how wearable data (Oura scores, HRV, sleep scores), viral health claims, and confident internet voices can quietly reprogram how people feel about their own bodies. They get into the iron and ferritin trend sweeping women's wellness content, the marketing spin behind "medical grade" red light panels, and why more information often means less clarity. The conversation turns clinical with a look at total plasma exchange (TPE) and EBOO — who actually needs them versus who's chasing a shortcut — and into peptides, where Lauren shares her current protocol (BPC-157, TB-500, Kisspeptin) for perimenopause and tissue repair, while Freddie talks through his own stack, including low-dose retatrutide. The back half centers on fascia: Lauren's four-day cadaver lab course, and what healthy fascia looks and feels like compared to fascia shut down by scarring, dehydration, and a sedentary life — and what that means for how anyone moves, rolls, and recovers. Episode Highlights: 1:22 — What Lauren actually does as a functional health practitioner 2:16 — How her approach has evolved over the last decade 4:00 — Wellness has gotten more complex: peptides, PEMF, and high-level interventions go mainstream 5:24 — Are we actually getting healthier with more access to information? 8:45 — Context vs. content: why we overcomplicate health 14:00 — The double-edged sword of wearable data (the Oura ring example) 16:32 — Freddie's 4-hour no-food-before-bed rule and HRV 18:42 — Reclaiming ice baths and contrast therapy from online noise 21:41 — Stop demonizing what nature already gave us 24:14 — The iron/ferritin trend and the danger of one-size-fits-all advice 26:07 — Resonant breathing and finding your personal breath rate 28:55 — Why ferritin is trending in women's health right now 33:00 — Red light marketing claims and the "medical grade" myth 36:49 — Freddie's dog: the ultimate biohacker with no placebo effect 38:21 — Total plasma exchange (TPE): Freddie's first exposure and the current craze 41:42 — TPE recovery time and lymphatic drainage as a lower-cost alternative 43:03 — Who actually needs TPE vs. who's chasing a quick fix 44:46 — EBOO explained: ozonating and filtering the blood 50:41 — Lauren's peptide protocol: BPC-157, TB-500, and Kisspeptin for perimenopause 53:09 — Freddie's peptide stack and why retatrutide outperformed GLP-1s for him 56:24 — Lauren's cadaver lab experience: two bodies, two very different stories 1:00:00 — What healthy vs. unhealthy fascia actually looks like 1:04:54 — Foam rollers vs. towel work vs. long holds for releasing fascia 1:07:53 — Closing thoughts and where to find Lauren and the BioHacker Babes Connect with lauren Instagram: https://www.instagram.com/lauren_sambataro Website: https://www.laurensambataro.com Podcast (BioHacker Babes): https://www.biohackerbabes.com Upgrade Your Wellness: LightPathLED: https://bit.ly/4gwYiUh Code: beautifullybroken Explore the new FDA Cleared Aurawell PEMF: Book A Call Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD 30% off with Code: BEAUTIFULLYBROKEN MaxGen Labs: https://maxgenlabs.com/BEAUTIFULLYBROKEN CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/freddie.kimmelYouTube: https://www.youtube.com/@beautifullybrokenworld Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Everywhere you look people are talking about peptides. But what exactly are they, how do they work and how safe are they for human consumption? Mike and Ross review the evidence, discuss the politics that continue to muddy the waters around peptide efficacy and regulation, and examine the dangers of using untested peptides. The team also look into the role of the popular GLP-1's that have revolutionised diabetes and weight loss and the controversial BPC-17 peptide, touted as a miracle treatment for tissue repair.LinksThe Undark article that describes the history of BPC157More on the FDA and the complex regulation of peptidesA report on one of the FDA decisions about peptides - in this case BPC157 and KPVA paper from the discoverer of BPC157, who has published more than three-quarters of the research on itThe human safety study on BPC157, with its two participantsSystematic review of BPC157 evidence, suggesting promise but cautionA well researched article by Dr Eric Topol raising concerns about safety and regulatory decisionsExample of a public warning from a regulatory body, this one from South AfricaFollow the money - Fortune 500 piece on why deregulation could create a multibillion dollar marketBecome a Supporter of The Science of Sport for about the price of a coffee, or a gel, and help us keep the lights on, and Gareth's candle burning! Plus, you'll get ad free listening, a weekly Applied show, and a community that argues better than the internet does! Hosted on Acast. See acast.com/privacy for more information.
What actually happens to a patient a year into real, supervised peptide therapy? In the final episode of our peptides series, Dr. Melissa Jones and host Jamie Preston close the loop on the story that opened this whole series — and get honest about what changed, what didn't, and what every provider and patient still needs to know. This episode goes beyond the science into the human side of the story: what it actually feels like when chronic pain resolves, when weight loss becomes life-changing rather than cosmetic, and when a skeptical clinician becomes one of the most passionate advocates in the building. Jamie also shares his own journey — turning 50, managing diabetes, and reaching his goal weight — as a real example of what supervised, responsible care can look like over time. In this episode, you'll hear: An update on the chronic pain patient from Episode 1 — where he is now, and what's kept his results sustainable What the actual clinical data shows about supervised BPC-157 therapy, and where its limits are Why GLP-1 success is about far more than the number on the scale — confidence, mobility, and mental health The advice Dr. Jones gives new providers who feel nervous bringing up peptides with patients The single biggest myth about peptides she wants to put to rest for good The three things every patient should understand before they ever start a peptide This is the episode that ties the whole series together — not as a sales pitch for peptides, but as a case for doing this the right way, with the right people, for the right reasons. It's the last episode in this run, but it won't be the last time we talk about this. www.YourHealth.Org
Dr. Mike Israetel is an exercise scientist with a PhD in sport physiology and co-founder of Renaissance Periodization. He is also a competitive bodybuilder and Brazilian jiu-jitsu athlete.Show Sponsors:- Don't sleep on Ultra Pouches! New customers get 15% Off with code DALTON at https://takeultra.com- Go to https://www.stash.com/DALTON to get 15% off a monthly subscription or 30% off an annual subscription and to view important disclosure- Sign up for a $1 per month trial of Shopify at https://www.shopify.com/dalton - Try the Plaud Note Pro at https://www.plaud.ai/DFP Discover more: https://bit.ly/4us0aCq - 10% off code: DFP10Amazon: https://amzn.to/4eVYdcuNotePin S: https://amzn.to/3RUZk2p 10% off code: DFPamazonMike's Links:RP: https://rpstrength.comYouTube: https://www.youtube.com/@RenaissancePeriodizationIG: https://www.instagram.com/drmikeisraetelRP IG: https://www.instagram.com/rpstrength Dalton's Links:Podcast IG: https://www.instagram.com/daltonfischerpodcast Personal IG: https://www.instagram.com/daltonfischer 00:00 | Intro01:33 | Ozempic & GLP-1s11:05 | Side Effects15:13 | TRT31:48 | Lifestyle Effects on Testosterone37:27 | The "Serene Revolution" (Anxiety & Depression)42:43 | Peptides46:15 | BPC-15748:19 | Steroids1:01:31 | Hair Loss1:07:34 | The Future of Drugs1:12:55 | Attractive People Are Treated Differently in the World1:27:06 | Looksmaxxing1:32:58 | AI2:00:58 | Palantir & Flock Cameras2:14:50 | Robotics & Figure AI2:26:25 | Outro
Running culture is changing fast. Athletes now share every workout, fans follow races year-round, money and attention are concentrated around a handful of major events, and ultrarunning is being forced to confront doping, peptides and what “clean sport” actually means.Ultrarunner, coach and podcast host Zach Bitter joins Jeff Garmire to discuss whether money is ruining trail running, the rise of athlete content, Josh Kerr calling his shot at the mile world record and why real fandom has finally arrived in ultrarunning.They also explore the growing difficulty of entering Western States and Hardrock, what multi-day runners are doing differently, sleep strategies in backyard ultras, why runners start 100-milers too fast and what modern ultrarunning can learn from the wild history of pedestrianism.Finally, Zach offers a nuanced look at PEDs, BPC-157, therapeutic use exemptions and whether races may eventually need separate competitive and participation categories. He also shares an update on his return to running after a blood clot and the possibility of another 100-mile race.Support our Sponsors: Janji (code: Freeoutside): https://snp.link/a0bfb726CS Coffee: CSinstant.coffeeGarage Grown Gear: https://snp.link/db1ba8abSubscribe to Substack: http://freeoutside.substack.comSupport this content on patreon: HTTP://patreon.com/freeoutsideBuy my book "Free Outside" on Amazon: https://amzn.to/39LpoSFEmail me to buy a signed copy of my book, "Free Outside" at jeff@freeoutside.comWatch the movie about setting the record on the Colorado Trail: https://tubitv.com/movies/100019916/free-outsideWebsite: www.Freeoutside.comInstagram: thefreeoutsidefacebook: www.facebook.com/freeoutside#Trailrunning #Runningnews #Outdoors #Outdooradventure
Andrea breaks down the latest FDA news surrounding BPC-157 and explains what the recent recommendation really means without the hype. She shares why this peptide has been on her radar for years, her own personal experience using it for recovery, what current research is exploring, and why it's become such a popular topic in the fitness and wellness world. Whether you've heard people talking about BPC-157 or you're simply curious about the buzz, this episode offers a balanced, easy-to-understand overview of where things stand today.Make Fit Simple is sponsored by KION Go to Getkion.com/simple for 20% off.Join my newsletter! https://www.deliciouslyfitnhealthy.com/emlsFollow the Make Fit Simple Podcast@MakeFitSimplePodcastHave a suggestion for a topic click HEREHave a suggestion for a guest click HERENEW! Leave a question for Andrea HERE on SpeakPipe!Follow Andrea on Instagram@deliciouslyfitnhealthy@dfh.training.picsTraining & Coachinghttps://www.deliciouslyfitnhealthy.com/linksVisit Andrea's Websitewww.deliciouslyfitnhealthy.comProduced by Light On Creative Productions
What is the Glow Stack, and why are BPC-157, TB-500, GHK-Cu and NAD+ attracting so much attention in recovery, menopause and longevity research? In this episode, Kim Constable shares the personal story behind her introduction to peptides and the four-compound combination she refers to as the Glow Stack. As Kim moved further into menopause, she noticed that her body was no longer recovering as it once had. Her joints hurt, her gluteal tendinopathy became increasingly painful, training felt harder and she frequently woke feeling tired, stiff and inflamed. After discovering GLP-1s and experiencing changes in her own joint pain, digestion and brain fog, Kim began researching the wider world of peptides. Her early research led her to BPC-157 and TB-500, followed later by GHK-Cu and NAD+. Kim shares the changes she personally noticed after combining these compounds, including changes in recovery, strength, sleep, energy, skin, nail growth and hair growth. She then moves beyond her own experience to explain what each compound is being investigated for. Inside this episode: • How menopause affected Kim's recovery, joints and energy • Why she first began researching BPC-157 and TB-500 • What BPC-157 is being studied for in relation to tissue repair and blood-vessel formation • How TB-500 may support the migration of repair cells through damaged tissue • Why GHK-Cu is being investigated for collagen, inflammation and skin structure • The role NAD+ plays in cellular energy and ATP production • How the four compounds may work together rather than performing the same job • The changes Kim personally noticed in her skin, hair, nails, recovery and strength • Why personal experience is not the same as clinical evidence • The limitations of the existing research, particularly where human trials are limited • Potential risks, individual reactions and the importance of regular blood testing • Why hormone health and HRT may still form the foundation of menopause support • Why a compound that appears helpful for one woman may not suit another Kim explains the science using a construction-site analogy: BPC-157 may help create the pathways, TB-500 may support the cellular vehicles travelling through them, GHK-Cu may provide the rebuilding instructions and NAD+ supplies the energy needed to power the work. This episode is an accessible introduction for women who are curious about peptide research but want the mechanisms, limitations and personal experiences explained in straightforward language. This podcast is for educational and informational purposes only. Kim is not a doctor or licensed medical practitioner, and nothing discussed should be interpreted as medical advice, a treatment recommendation or a personal protocol. Nothing in this episode is a recommendation to purchase, reconstitute, dose, administer or use any research product. Research products supplied by Verified Vials are intended strictly for laboratory research and are not for human consumption or medical use. Always consult an appropriately qualified healthcare professional about your individual health. ✨ Follow Kim Constable online for more real talk and daily motivation:
BPC-157 is now used as a recovery peptide for tendon injuries, muscle strains, and stubborn joint problems. Some people report remarkable results, while others feel nothing. But its story did not begin in sports medicine. It traces back through human stomach fluid, an old Yugoslav research program, pharmaceutical development, and decades of experiments that still leave major parts of the peptide's history unresolved. This investigation follows that evidence from the beginning to find out what BPC-157 actually is, what it may be doing, and how it became the healing peptide.Time stamps:0:00 – What BPC-157 really is2:02 – How it got its name4:50 – What the animal studies show8:33 – The science that still doesn't add up10:28 – A stability problem nobody talks about12:17 – The human trial history13:43 – A missing piece in the story15:17 – What the evidence still doesn't prove16:29 – Where things stand now
Kathy Wieliczko is a nurse practitioner who learned about hormone replacement therapy from Real Housewives of New Jersey. Not from school, or from her doctor, but from Bravo. Her own GYN told her she'd go up a few dress sizes in menopause and that was just life now. Kathy said absolutely not, blocked every person she knew, started an anonymous Instagram at 52, and turned into the girlfriend we all wish we'd had. (You know, the one who tells you the truth in the back of the Uber at 2 AM.) She gives Meg and Carrie the whole list this week. The alcohol. The Peloton habit that had her cortisol through the roof. Why she quit chasing splat points and started lifting heavy for 30 minutes instead. And then they get into peptides, GLP-1 microdosing, and the sketchy vials people are mixing at their kitchen counter like Walter White. Pull up a chair, sis. This is just girl friends talking, not medical advice. Go see your own provider. Find Kathy Instagram: @midlifeinspo Chapters: 00:00 The tips nobody wants to hear 00:40 Meet Kathy Velichko, aka Midlife Inspo 01:15 Why she blocked everyone she knew 02:10 Learning about HRT from Real Housewives 03:00 The GYN who laughed at her 04:20 Megan's testosterone wake-up call at 31 05:35 A nurse practitioner on the struggle bus 06:10 The training doctors never got 06:55 The 30-year reunion victory lap 07:50 Meeting at a Dallas photo shoot 09:30 Cattywampus lips and a ruined birthday 11:45 Doing your makeup when you can't see 13:20 Top five: alcohol, cardio, weights, protein 16:20 Nurses graze all day: the three meal reset 17:45 Walking, cortisol and quitting Orange Theory 19:15 How a GLP-1 company changed her mind 20:15 Microdosing GLP-1: food noise and labs 21:20 The stigma and the people still denying it 22:30 Peptides 101: copper peptide and NAD 23:45 Gray market vials and the Walter White problem 25:05 Big Pharma, compounding and the FDA fight 27:50 BPC-157, Wolverine and the vial in her fridge 30:15 J.Lo, Gwyneth and what's really going on 31:00 Start with one thing before peptides 32:20 How long until you see results 33:20 From one post at 52 to coaching women 34:45 Where to find Kathy
"If you don't get those foundational behaviors down, there ain't nothing a peptide's gonna do for you,” says Rachele Pojednic, Ph.D. Pojednic is a professor of Sports Nutrition and Exercise Physiology at Stanford University and is the Chief Science Officer at Restore. Her work examines nutrition, supplementation and physical activity interventions on muscle physiology, performance and recovery, as well as muscle related chronic disease, with a particular focus on women. Pojednic holds a Certified Strength and Conditioning Specialist (CSCS) certification from National Strength and Conditioning Association (NSCA) and is board certified Health Coach from the National Board of Health and Wellness Coaches (NBHWC). She has a particular passion for science communication and has been a consultant and writer for many prominent news outlets, including NPR, Time, The Washington Post, and Popular Science. Show notes: 00:00 - The difference between science & wellness 06:30 - The big vs. little levers of health 08:40 - What we do & don't know about peptides 11:45 - A study on supplement stacking gone wrong 13:55 - Next-gen peptides (BPC-157 & more) 18:20 - All about NAD, NR, & NMN 29:57 - Creatine for muscle & brain health 33:48 - Looking at leucine & amino acid profile in protein 36:48 - Why fasting advice for women often backfires 40:24 - Stop chasing perfection 43:45 - How to use wearables & lab testing 50:13 - Bridging science & wellness Referenced in the episode: For more about Pojednic, visit her website: https://www.rachelepojednic.com/ mindbodygreen's creatine brain supplement: https://shop.mindbodygreen.com/products/creatine-brain mindbodygreen's whey protein: https://shop.mindbodygreen.com/products/clear-whey-protein We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
Broadcast from KSQD, Santa Cruz on 8-06-2026: >ul> An emailer with persistent nine-month nerve damage in her right leg after a hysterectomy asks whether peptides could help. Dr. Dawn attributes the injury to lithotomy positioning during surgery, then reviews the main nerve-regeneration candidates in the FDA peptide review pipeline: BPC-157 (Body Protection Compound, strong rat data on sciatic nerve recovery with thicker myelin sheaths), intracellular sigma peptide (targets glial scar CSPGs blocking CNS regrowth), C3 peptide 156-181, GHK-Cu (copper peptide, upregulates nerve growth factor and neurotrophin-3), self-assembling hydrogel scaffolds for bridging nerve gaps, ARA-290/cibinetide (an erythropoietin fragment with early small fiber neuropathy trial data), and Semax (used internationally for stroke rehab). She adds standard functional-medicine adjuncts: alpha-lipoic acid, methylated B12, and methylfolate at high doses for six months. An emailer asks about safe features when buying an infrared sauna. Dr. Dawn covers three concerns: EMF exposure (look for shielded/grounded heaters testing under 1 milligauss at seat level, avoid unshielded Wi-Fi and Bluetooth panels); VOC off-gassing (avoid plywood, particle board, and MDF because of formaldehyde and benzene release, and avoid Western red cedar and pine because of high terpene emissions and instead choose poplar, basswood, or eucalyptus); and avoid built-in oxygen ionizers, which produce ozone as a coronal-discharge byproduct that irritates airways and generates secondary oxygenated VOCs. Dr. Dawn covers the surprisingly long list of medications that raise estrogen in middle-aged men—including nearly all antidepressants and antiepileptics, statins, NSAIDs (specifically naproxen and indomethacin but not ibuprofen), most blood pressure medications, PPIs, H2 blockers, Parkinson's drugs, antihistamines, and muscle relaxants. She recommends annual monitoring of the estrogen-to-testosterone ratio and offers rebalancing options: topical chrysin (blocks aromatization), indole-3-carbinol, calcium D-glucarate (blocks enterohepatic estrogen recirculation), soy (competitive receptor inhibition), and grape skin extract. The first mRNA-based flu vaccine was approved this week for adults 50 and over. Beyond the 27% improvement in seasonal efficacy over conventional shots, the strategic advantage is manufacturing speed. This will be critical when or if bird flu mutates to respiratory human transmission. Since mRNA vaccine can be reprogrammed from a new viral sequence in weeks versus the three-to-four-month growth cycle for conventional flu vaccines, rapid response can save lives. But mRNA vaccine side effects include more injection-site pain and fatigue - more like a tetanus shot than a traditional flu shot.. A Spanish prospective study of chemicals affected puberty in the young studied 500 girls followed from ages 7-10 and again at 14-16 used urine chemical measurements as objective exposure markers rather than food diaries. Ethylenethiourea, a metabolite of dithiocarbamate fungicides used heavily on strawberriess,was associated with earlier menarche, while a chlorpyrifos metabolite was associated with delayed menarche. this latter effect was more pronounced in overweight girls whose fat tissue concentrated the compound. Dr. Dawn recommends organic strawberries and keeping children away from fumigated fields. University of Pennsylvania School of Dental Medicine researchers developed a chewing gum from lablab beans containing the natural antiviral protein FRIL, which reduced oral HPV by up to 93% in samples from head and neck squamous cell carcinoma patients. The gum also suppressed Fusobacterium nucleatum and Porphyromonas gingivalis, oral bacteria that promote cancer recurrence. Michigan State University's Hamburger lab studying delphinium (larkspur) alkaloids joined forces with Tomáš Pluskal's Czech Academy of Sciences lab studying wolfsbane (monkshood) after meeting at a Barcelona conference. Together they mapped the biosynthetic assembly line for aconite—an alkaloid with valuable applications against malaria, pain, cancer, and agricultural pests but impossibly slow to extract from source plants—and cloned the pathway into tobacco, which grows aggressively and produces large quantities of the compound. An emailer named in the message asks about an incidentally-discovered enlarged aorta on CT. Dr. Dawn notes it officially becomes an aneurysm at 4 cm (annual monitoring) or 5 cm (six-month monitoring), with smoking cessation critical since tobacco directly weakens the aortic wall. She describes the "zipper of fire" back pain of dissection versus catastrophic rupture, and notes Medicare covers a one-time screening ultrasound for ever-smokers over 65.
Perez Hilton had a public breakdown on TikTok this week, and people are asking what actually happened. Chalene Johnson breaks it down with trigger warnings, including how it connects to his defamation fight with Blake Lively and Ryan Reynolds and his brush with death from sepsis this past March. Chalene also digs into why qualified applicants, including former Elle editor Stacy Deguide, who deleted 15 years off her resume just to get a callback, are vanishing into what recruiters call an AI hiring black hole. A Stanford study found that roughly one in five companies now let algorithms reject candidates before a human ever sees a resume, and Chalene walks through how hiring software like Workday's may be filtering out midlife workers, new grads, and everyone in between. Rounding out the episode is this week's crackdown on the black market peptide trade. An Indiana company called Paradigm Peptides was sentenced after selling to 54,000 customers in 80 countries, a Michigan dealer got 20 years for relabeling semaglutide as Ozempic, Wegovy, and Retatrutide, and a licensed doctor running a Utah clinic called True Health was caught repackaging BPC-157, TB-500, and other peptides under fake labels for more than 200 patients. Topics discussed: Perez Hilton, Blake Lively, Ryan Reynolds, Justin Baldoni, TikTok, Ariana Grande, Stacy Deguide, Elle, Stanford University, Workday, Paradigm Peptides, True Health, Justin Watkins, Ozempic, Wegovy, semaglutide, Retatrutide, BPC-157, TB-500, GLP-1, sepsis, ageism. Go Beyond The Podcast Join Chalene on her private podcast
Full show notes: https://bengreenfieldlife.com/peptides2026 In this episode with Dr. Matt Cook, recorded days after he returned from Washington, D.C., you'll get a breakdown of what just happened to peptides in the United States. You'll hear what the FDA's Pharmacy Compounding Advisory Committee actually voted on, why seven popular peptides were pulled two years ago, which six of the seven were just recommended for the bulk list, which one was left off, and what all of it means for your ability to get peptides legally from a pharmacy instead of the gray market. You'll also get a guided tour of the peptides themselves: BPC-157 for gut and tissue healing, KPV for inflammation, TB-500 for cell migration and wound repair, MOTS-c as an exercise mimetic, Semax for memory and learning, Epitalon for sleep and longevity, and DSIP for sleep. Dr. Cook explains why peptides behave so differently from ordinary drugs, walks through a safety review covering millions of doses, and shows how his company LifeOS pulls your labs, wearables, and genetics into one HIPAA-compliant place. And if you want to keep every peptide straight, Dr. Cook built a peptide cheat sheet covering what each one does, how to dose it, and where to source it. Episode Sponsors: Timeline: Give your cells new life with high-performance products powered by Mitopure, which unlocks a precise dose of the rare Urolithin A molecule to promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. Xtendlife Prosta Support Advanced: Comprehensive daily prostate support combining clinically studied ingredients like saw palmetto and beta-sitosterol with vitamins, minerals, and botanicals. Visit Xtendlife.com/BensChoice and use code GREENFIELD for 15% off. Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/BEN with code BEN. BIOptimizers Magnesium Breakthrough: Seven essential forms of magnesium in one full-spectrum serving to help you relax, unwind, and sleep deeply so you wake up refreshed. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off.See omnystudio.com/listener for privacy information.
I'm a biohacker with a peptide fridge, and right now I am injecting absolutely nothing. That is probably not what you expected me to say. The internet makes it look like the goal is more compounds, stacked higher, forever. It is not. The goal is to use the right tool for a specific window, then come off it. In this solo episode I open my actual fridge. I walk through every peptide I have run recently, the real dose, why it went in, why it came out, and why I am on a full break right now. I cover my injury repair pair BPC-157 and TB-500, my body composition experiments with AOD-9604 and a Retatrutide microdose, my beauty and longevity layer with GHK-Cu and NAD nasal spray, and my brain and mood pair Selank and Semax. Then I explain why I am cycled off everything, and how to build your own stack for a female body instead of copying mine. This is my personal experience for education, not medical advice, and peptides are provider territory. If you want me to help you build and sequence your own stack around your goals and your labs, you can book a free call here. Join The LongHer Life Longevity Community for women-specific guidance on peptides, hormones, and longevity. Timestamps: 02:20 - The confession: a biohacker with a peptide fridge, injecting nothing right now 02:55 - Why more is not better, and who is really selling you peptides forever 04:04 - Work with me one on one: free 15-minute calls for women worldwide 05:11 - Foundations first: hitting 140 g of protein a day and creatine 06:39 - Two years postpartum, building muscle, and my genetics 07:57 - Sleep and recovery: my new Oura Ring and tracking HRV 08:43 - Where my peptide year started: a wake surfing knee injury 09:35 - BPC-157: how it works, my dose, and doubling it to heal my knee 11:17 - Who BPC-157 is for, injecting near the injury, and breastfeeding 12:41 - TB-500: the classic repair partner, my loading dose, and tapering off 13:58 - Body composition peptides: AOD-9604 and Retatrutide microdosing 14:25 - AOD-9604: gentle fat metabolism, my 300 mcg fasted dose, who it suits 18:46 - Retatrutide explained: the triple agonist people call GLP-3 22:25 - Why I would buy Retatrutide now and store it in your fridge 24:56 - Serious weight loss vs my 0.5 mg microdose, and the nausea I felt 28:02 - The GLP muscle and nutrient warning every woman needs to hear 29:18 - GHK-Cu: the copper beauty peptide for skin, hair, and nails 30:47 - Managing the GHK-Cu skin reaction, and when to take a break 32:24 - NAD nasal spray: energy, focus, and longevity the gentle way 35:22 - Selank: my favorite calming peptide for anxiety and stress 37:45 - Semax: the focus peptide, and how I pair the two 39:04 - Why I am cycled off everything right now: the full deload 43:53 - How to build your own stack without copying mine 44:38 - Labs and supplements I am running: SiPhox, Function Health, Needed 45:44 - Start gentle, stay at 3 to 5 peptides, and cycle off 46:27 - Free peptide sources and my digital peptide planner 48:18 - Close: work with me, and why the break is the protocol Resources: Work with me one-on-one: book a free 15-minute call. The Her Stack Planner to track your doses, timing, and cycles. My Peptide Source Guide with vetted sources for Canada, the US, and global, plus supplies. Join The LongHer Life Longevity Community. Products mentioned: AgelessRx for the NAD nasal spray and GHK-Cu cream. Code: BIOHACKINGBRITTANY. SiPhox Health at-home blood testing in Canada. Code: BRITTANY20. NiaHealth at-home labs in Canada. Function Health labs in the US. Needed prenatals and omegas. Code: BIOHACKINGBRITTANY. Oura Ring for sleep and HRV tracking. Let's connect: Instagram and TikTok @biohackingbrittany, and Facebook. Shop everything I use at biohackingbrittany.com. Listen on Spotify, Apple Podcasts, and YouTube Music. This is for educational purposes only. This is not medical advice.
First, let's break down what BPC-157 actually is. BPC stands for Body Protection Compound, and the 157 refers to the specific amino acid sequence that makes up this peptide. It's a synthetic peptide derived from a protein found in our stomach, specifically in gastric juice. This peptide has been shown to have a range of healing properties, particularly related to tissues like the gut, muscles, and tendons. The reason BPC-157 is getting attention in the realm of acid reflux and gastrointestinal issues is because of its potent regenerative abilities. Some studies suggest it could promote healing in the gastrointestinal tract, reduce inflammation, and improve the gut barrier—key factors for people dealing with acid reflux. Read the Full Episode Transcript: https://pepties.com/acid-reflux-relief-with-bpc/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order: https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/
Tom Rowland Podcast Episode 1022 is a conversation with Dr. Kevin Stone, the San Francisco orthopedic surgeon behind The Stone Clinic, about biologic knee replacement — rebuilding a worn joint with donor meniscus cartilage and regrown articular cartilage instead of replacing it with metal. We also cover what “bone on bone” actually means, partial versus total knee replacement, robotic cementless implants, PRP and stem cell recruitment, the truth about BPC-157, and why he thinks most people told they need a total knee replacement do not.
Leveling Up: Creating Everything From Nothing with Natalie Jill
Is adrenal fatigue even real, or have we all been chasing the wrong diagnosis? I sat down with Dr. Allan Bacon, a dentist turned nutrition and powerlifting coach who has built his career sitting in the middle ground between conventional medicine and the wellness world, calling out both sides when the science says they've gotten it wrong. And one of the most eye opening parts of this conversation was about adrenal fatigue, a term so many of us have used to describe our own exhaustion. Dr. Bacon walked me through why it isn't actually a recognized medical diagnosis, what's really going on in our bodies when we feel that drained, and why the label matters so much for finding something that actually helps. We also get into the placebo effect, the truth about peptides like BPC-157, and what the research really says about our metabolism in midlife. We Go Deep On: Why "adrenal fatigue" isn't an actual medical diagnosis, and what it means that our adrenals are usually functioning just fine The real reason we feel that drained, and why "stress and burnout" is a more accurate description than adrenal fatigue What actually helps when we're running on empty, including specific, research backed options like glycine and magnesium Why the placebo effect showed up as a 22 pound strength jump in trained powerlifters, and what that means for how we think about our own bodies What the research does and doesn't say about BPC-157 and peptides A landmark study showing metabolism doesn't actually change from age 20 to 60, and what that means for the way we've been told to think about midlife Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube Learn More About Dr. Allan Bacon Instagram ➜ https://www.instagram.com/drallanbacon Website ➜ https://mauiathletics.com/ Thank you to our show sponsors: TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit For advertising inquiries: https://www.category3.ca/ Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.
On this episode of the 40+ Fitness Podcast, Coach Allan breaks down the fight playing out right now in Washington, DC, between GLP-1 medications and peptides. The two keep getting mentioned in the same breath, but they sit on opposite sides of the evidence line. GLP-1s like semaglutide and tirzepatide are tested medications with known dosing and documented side effects. Peptides like BPC-157 and TB-500, the so-called Wolverine stack, are not approved for human use and live in a gray market built mostly on rat studies and anecdote. Coach Allan walks through the recent FDA Pharmacy Compounding Advisory Committee panel that recommended approving 6 of 7 peptides even after the agency's own scientists raised safety concerns, and he points out what it means for you. Time Stamps: 02:54 GLP-1s and peptides, framing the fight 04:26 Peptides and the gray market 05:20 The cheating debate around weight-loss drugs 06:07 The peptides: AOD-9604, BPC-157, TB-500 07:00 Branding and hype: the Wolverine stack 08:50 How both sides market GLP-1s and peptides 09:54 RFK Jr. and what the FDA is for 11:04 Follow the science, not the phrases 12:57 Off-label prescribing and thin peptide data 14:34 Gray market and inconsistent manufacturing 15:47 The FDA compounding panel meets 16:32 FDA scientists warn against approval 17:43 The panel's conflict of interest and 6-of-7 recommendation 19:50 The Joe Rogan ivermectin parallel 22:20 Peptides, cancer risk, and personal caution 23:11 The N=1 experiment and its limits 26:33 Making the decision that's right for you Links - Work with Allan one-on-one (a few coaching slots are open right now): coach@40plusfitness.com - 40+ Fitness: https://40plusfitness.com
Are you tired of working out endlessly and trying every generic diet, only to see zero results? What if the problem isn't your discipline, but a lack of information about your unique biology? In this episode of The Level Up Podcast, Paul Alex sits down with Dora Maria, a Bay Area native, UC Berkeley graduate, and former healthcare executive who spent 15 years within the medical system. Dora shares her incredible journey from growing up in a garage while her mother battled breast cancer, to reaching the peak of her career, only to find herself in the back of an ambulance at 39 years old. After struggling with pre-diabetes, a 50-pound weight gain, and uncontrolled hypertension, Dora realized that the traditional healthcare system is designed for surviving, not thriving. She took her health into her own hands, utilizing DNA testing and advanced lab panels to uncover exactly what her body needed. Dora breaks down the truth about popular weight loss trends, explaining why the Keto diet landed her in the ER with appendicitis, and why high-intensity workouts like Orange Theory were actually causing her body to hold onto fat. She also dives deep into the world of peptides, explaining the difference between weight loss GLPs (like Ozempic and Zepbound) and powerful longevity peptides (like BPC-157 and the Wolverine stack) for tissue regeneration and anti-aging. If you are a high-performing professional or entrepreneur looking to optimize your health, buy back your time, and finally get a customized plan that fits your DNA, this episode is a game-changer! Make sure to follow Dora on Instagram: @iamdoramaria Listen to The Level Up Podcast w/ Paul Alex: Available on Apple Podcasts and Spotify. Learn more about your ad choices. Visit megaphone.fm/adchoices
https://youtu.be/ifjzCPrAVyYAPR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comRP Hypertrophy Training App: rpstrength.com/nyle (code nyle)00:00:00 Intro00:01:40 The Ultimate Hair Regrowth Formula00:07:14 Red Light Therapy: Fact or Fiction?00:10:41 The Sweet Spot for Peptides00:12:11 BPC-157: Healing Injuries Fast00:19:05 Pharma vs. Generic HGH00:44:39 Mitochondrial Reset Protocols00:51:26 The Dave Palumbo Science Debate01:01:39 Curing Severe Tendonitis01:08:33 Serostim, Genotropin & Anavar01:13:06 Cryotherapy & Muscle Growth01:17:39 Insane Endurance: Cardarine & AICAR01:23:29 Mega-Dosing MOTS-c & SLU01:29:18 Mirabegron & Sleep Disruption01:37:23 5-Amino-1MQ: Oral vs. Injectable01:41:33 Cruising in the Off-Season01:44:56 Nootropics for Tren Toxicity01:50:52 The Truth About Nasal Spray Peptides01:53:25 Fertility Protocols on Gear01:59:19 Palumbo Debate Aftermath02:00:24 Retatrutide & Heart Health02:01:52 High-Dose SLU Protocols02:05:39 Tapering Clenbuterol02:06:38 Extreme Oral Steroids in Prep02:11:55 Trenbolone in the Off-Season02:12:54 Custom Peptide Stacks02:18:51 First Cycle Regrets02:22:09 Stopping Hair Loss on Gear02:25:40 Pinning HGH Pre-Workout02:28:01 Finding the Lowest Effective Dose02:31:35 Executive Nootropic Stack02:34:47 Pre-Workout Peptides02:36:40 CIA Background & Intelligence02:39:25 Final Thoughts & Legacy
FDA Advisory Panel Backs Six Peptides for Compounding Pharmacies Phil kicks things off with an update on the torn upper horn of his lateral meniscus, sustained just before a meet he ran anyway (600 lb squat, 600 lb deadlift) rather than sit out with his son. From there the hosts pivot to a Verywell Health piece by Amber Raiken on the FDA's Pharmacy Compounding Advisory Committee recommending looser restrictions on six peptides — BPC-157, TB-500, KPV, MOTS-c, Selank, and Epitalon — while rejecting a seventh, Emoxypine, over weak human results. Mike, drawing on a recent conversation with attorney Rick Collins, explains the split between FDA researchers (mostly opposed) and the non-physician advisory panel (mostly in favor), and why compounding-pharmacy oversight could at least guarantee sterile, accurately-dosed product versus the unregulated grey market. The group works through the thin evidence base for BPC-157 — including a sham-surgery knee trial showing a large placebo effect — alongside real anecdotes, including Phil's own faster recovery after hip surgery. They also cover the money and politics behind the FDA's shift, the rise of pre-loaded peptide pens mirroring GLP-1 marketing, sermorelin's prior FDA history, grey-market use of unapproved compounds like retatrutide, and how peptides moved from underground research-chemical circles in the '90s to today's mainstream, driven largely by biohacker influencers and the normalization of GLP-1 injections — now increasingly popular with women as well as men. They close by comparing peptide-assisted recovery in elite athletes (citing Patrick Mahomes) to the old anabolic-era "impossible" recovery stories, and debate what a sane regulatory and tracking system for peptides could look like. 00:00 Welcome and Hosts 00:20 Phil's Meniscus Tear and Meet Recovery 05:02 Transition to Peptide Regulatory News 06:18 FDA Advisory Panel and the Six Peptides 12:11 BPC-157 History and Anecdotal Evidence 17:02 Network Announcements and Newsletter 19:58 FDA Politics and Compounding Pharmacy Incentives 30:07 Six Peptides List and Emoxypine Rejection 34:59 A Proposal for Peptide Regulation and Tracking 37:28 How Peptides Reached the General Public 46:48 Elite Athletes and Faster Recovery Anecdotes 50:06 Wrap and Disclaimer Donate to the show via PayPal HERE.You can also join Dr Mike's Insider Newsletter for more info on how to add muscle, improve your performance and body comp - all without destroying your health, go to www.ironradiodrmike.com Thank you!Phil, Jerrell, Mike T, and Lonnie
LL LIVE Ep. 205: Part 2 is here and this time it's about what actually happened.Last episode, Dr. Paley walked us through what PRECICE MAX is and how it improved upon the PRECICE 2.2. This week, the exclusive launch is underway at the Paley Institute, and we're back with the first week numbers - how many patients, which nail sizes, and how people are actually recovering.Joining Dr. Paley this time is Dr. Craig Robbins, who's been doing these cases side by side with him all week. Timestamps - 0:00 Intro1:13 First Two Weeks of PMAX Cases at Paley Institute2:55 PMAX Weight-Bearing Capacity and FDA Labeling4:03 Why Nail Diameter Dramatically Changes Strength5:19 Early PMAX Experience and Hardware Performance6:13 Weight Bearing as Tolerated: The Paley Protocol9:06 Mobility Devices, Walkers, Canes, and Wheelchair Use10:48 Dr. Robbins on the Early Patient Experience12:02 Nail Sizing, Bone Canal Size, and PMAX Fit17:17 How the PRECICE Max Lengthening Mechanism Works18:31 Getting Patients Walking After Surgery21:13 Could Weight Bearing Improve Bone Healing and Consolidation?22:45 Live Patient Q&A Begins23:02 Is Unassisted Walking Safe Around Week Three?25:42 Can Tibia Patients Lengthen Beyond 5 cm With PMAX?28:28 Hotel Mobility and Daily Walking After Surgery29:03 What Changes After the Lengthening Phase Ends?30:00 Pre-Surgery Flexibility and Stretching30:58 Lengthening Greed and Realistic Height Goals32:02 Best Strategy for Maximum Safe Height Gain34:28 When Will PMAX Be Available Internationally?37:08 How Long Will Dr. Paley Keep Operating?37:57 Femurs First vs Quadrilateral Lengthening Strategy41:08 Tibia Lengthening After Achilles Tendon Repair42:05 Hardware Removal Timing After Femur and Tibia Lengthening43:28 Vitamin D Levels and Bone Health Before Surgery46:11 PMAX Nail Testing, Lengthening Issues, and Transparency49:19 Is Quadrilateral Lengthening Safer With PMAX?54:04 Complex Medical Conditions and Surgery Eligibility55:39 Does More Walking Increase Risk of Pre-Consolidation?56:37 ERC Questions, Nail Sounds, and Troubleshooting57:35 Monitoring Lengthening to the Millimeter59:00 Same-Day Follow-Up and Team Coverage at Paley Institute1:00:28 Bone Turnover Markers and Metabolic Bone Health1:01:58 PRECICE Max Pricing and Comparing Centers Fairly1:07:24 Peptides, BPC-157, Stem Cells, and Exosomes1:11:51 Closing Thoughts and Future PMAX Follow-Ups1:12:48 Dr. Paley: Cautiously Optimistic About PMAX1:14:50 Outro
Send us Fan MailThe Krewe is at it again, and welcomes in our viewers on WGNO's web application in New Orleans!We're exploring how we have to make conscious decisions to will the good of other for the sake of other, even when we have people like Anthony Fauci who was advising against the facts he had during the Covid "pandemic"We won't take the "FiF" amendment once much less 100 + times, we'll just review another weekly whiskey, dive into the full Fauci conversation, as well as BPC-157 and the recent trend of online sports betting apps not paying people who beat them at their own game. Tell your friends, to like, share and follow your Implicit Bias!Support the show
Full Show Notes: https://bengreenfieldlife.com/503 In this solosode, you'll get the latest research on the questions I hear most: whether the peptide BPC 157 can cause cancer, the body fat percentages people rate most attractive for men and women (and how low is too low), how a "dad bod" before conception can affect your future kids' health, how "myo-reps" deliver the same strength and size gains in a fraction of your gym time, and whether creatine is bad for your kidneys. You'll hear why BPC 157's blood-vessel growth is not the same as the way cancer feeds a tumor and why healthy tissue has nothing to fear from it, how excess body fat quietly lowers testosterone, and why the most attractive body fat ranges line up almost perfectly with the ranges that support healthy testosterone, fertility, and a long life. You'll also walk away with the body fat targets actually worth aiming for, a simple way to shorten your time in the gym, and the creatine myths you can finally stop worrying about. Episode Sponsors: ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off. ButcherBox: Premium, responsibly sourced meat and seafood delivered to your door. New customers get a free protein of their choice for a year, plus $20 off the first box, at ButcherBox.com/BEN. Tiny Health: An at-home microbiome test that maps your full gut ecosystem and gives personalized, evidence-based diet, lifestyle, and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN. Qualia Stem Cell: A science-backed supplement that supports your body's own stem cell function for recovery and healthy aging, taken just four days a month. Visit qualialife.com/boundless and use code BOUNDLESS for 15% off. Young Goose: Cutting-edge skincare that supports your skin's cellular health. Visit younggoose.com and use code BGF10 for 10% off.See omnystudio.com/listener for privacy information.
Over 500 published papers stand behind one of the internet's most popular peptides, but fewer than 30 of the humans studied are in them. Dr. Gabrielle Lyon separates the molecule from the marketplace so you can tell real evidence from good marketing.In this solo episode, Dr. Gabrielle Lyon discusses:Why BPC-157's "mountain of evidence" collapses to a 99.7% animal-to-human ratio - 544 papers, but fewer than 30 humans across three uncontrolled pilot trialsHow to place any peptide on the spectrum from FDA-approved (GLP-1s like semaglutide) to investigational to compounded, and why "GLP-1s work, so peptides work" is a trapWhat the FDA quietly did in April 2026, and why removing a dozen peptides from its safety-concern list was driven by policy pressure, not new safety dataThe 4 questions to run on any peptide before you inject level of evidence, what the study measured, where it's sourced from, and whether it's banned in tested sportWhy the "boring work", resistance training, protein-anchored nutrition, and real recovery beat almost anything in a vialIf something is going into your body through a needle, the standard has to be higher than three words on a label that say "research use only." This episode gives you the framework to protect yourself before spending a dollar or taking a shot.Thank you to our sponsors:Head to https://bit.ly/4ftfObn and use code DRLYON for 25% off sitewide. That is K-E-T-T-L-E and Fire dot com slash DRLYON, code DRLYON for 25% off. Also available at select Sprouts, Whole Foods, and Kroger locations nationwide.BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/4vZs75j OneSkin - Get 15% off at https://bit.ly/44XXQYy with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patient-inquiry/Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon Chapters00:00 - Introduction01:30 - What a peptide is03:40 - The first mistake: treating peptides as one category05:50 - GLP-1s and the "peptides work" fallacy09:30 - FDA-approved peptides: tesamorelin and s15:40 - Repair peptides: BPC-157 and the Wolverine stack16:30 - 544 studies, 30 humans: the evidence gap20:00 - The strongest case for peptides25:30 - The strongest case against peptides29:00 - Compounded peptides and contamination risk30:00 - What the FDA quietly did in April 202633:40 - The 4 questions to ask before any peptide37:40 - The boring work that changes your life If you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
When Clint Phillips' young daughter suffered a stroke that left the right side of her body paralyzed, his family was told she might never walk or talk. The search for answers led him to build companies focused on medical second opinions, advanced longevity testing, AI-driven personalization and safer access to emerging therapies. In this episode, Clint sits down with Dr. Josh Axe to discuss how to identify the doctors and health metrics that truly matter, why too much tracking can sometimes make people less healthy, and what his laboratory testing revealed about the purity of popular peptides. They also explore the measurable effects of hope, purpose, gratitude, forgiveness and spiritual grounding—and why optimizing every number on your health dashboard may still leave something essential missing. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1
BPC-157, TB500, Ipamorelin... Should you dive in or wait until they're FDA-approved?Grab a free training or nutrition program on us: www.digitalbarbell.com/free
How to Survive a Shock PodcastFIVE PRIMARY POINTS of the PODCASTGreat leaders replace uncertainty with courage, faith, and hope.Drawing on lessons from the Campbell Trophy Summit, former Intuit CEO Brad Smith argued that leadership is about helping people navigate uncertainty by choosing courage over comfort, faith over cynicism, and hope over resignation. Purpose fuels courage, leaders build confidence by believing in others before they believe in themselves, and every person's work should connect to a larger mission.Consistency beats intensity over the long run.Athletic Brewing CEO Bill Shufelt shared how he realized he was “climbing a ladder leaning against the wrong wall.” After prioritizing his health and family, he built an $800 million company without returning to burnout. His key lesson: “Consistency outruns intensity over any long horizon.” Sustainable effort produces greater success than relentless hustle.Small changes, amplified by AI, can create extraordinary results.Nuclear engineer Dr. Tom Burns described how AI agents, trained to emulate his team's best engineer, identified a seemingly insignificant design change—a 0.1-inch modification to a centrifugal contactor—that doubled processing efficiency, accelerated a five-year project to less than a year, and saved taxpayers an estimated $5 billion. The lesson: identify the single metric that matters most and use AI as a collaborative partner to pursue transformational, not incremental, improvements.Elite performers share common principles.Across years of Campbell Trophy Summit speakers, recurring themes emerged: embrace difficult challenges (William McRaven), work to become “twice as good” and view struggle as a privilege (Condoleezza Rice), pair big dreams with disciplined execution (Steve Young), take action (”Let's go”—Ronnie Lott), be fully present for others, prioritize purpose over popularity, and lose yourself in service. Curiosity, humility, and grit consistently define high performers.Approach peptides with scientific caution, not hype.The podcast concludes with a review of the FDA advisory committee's recommendation regarding compounded BPC-157. While the committee recommended allowing compounding under specific circumstances, the evidence for safety and effectiveness remains limited. Dr. Mishra concludes that, for routine wellness or minor injuries, the current evidence does not justify widespread use. Until stronger human data exist, peptides should be reserved, if considered at all, for carefully selected patients who understand the uncertainties and risks.Copyright, VyVerse LLC. All Rights Reserved. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe
Gray divorce hit 36%, Danny Glover went public with his Alzheimer's diagnosis, BPC-157 quietly became legal again, a new bill takes aim at menopause discrimination at work, and celebrities are lining up to undo their own plastic surgery. Chalene Johnson breaks down why this is all happening at once. Chalene digs into why Kylie Jenner, Simon Cowell, and Kim Zolciak are all now saying they regret work they once defended, why Emily Simpson and Angie Katsanevas are living out the gray divorce numbers in real time, and why lawmakers like Debbie Dingell are stepping in on menopause discrimination at work. Topics discussed: gray divorce, Real Housewives of Orange County, Emily Simpson, Real Housewives of Salt Lake City, Angie Katsanevas, Shawn Trujillo, Danny Glover, Alzheimer's, magnesium, BPC-157, Botched Presents: Plastic Surgery Rewind, Kylie Jenner, Nicki Minaj, Simon Cowell, Kim Zolciak, Menopausal Workers' Fairness Act, Debbie Dingell Go Beyond The Podcast Join Chalene on her private podcast
Kilian Korth joined the show to have a discussion around ultrarunning's growing professionalization without sophisticated regulated drug testing, the limits and trade-offs of WADA/USADA-style regimes, and why "doping" as a blanket term obscures intent and severity. We unpack gray areas such as THC thresholds, TUE complexity for common medications, transparency vs backlash, influencer incentives, and the future pressure regenerative medicine and technology (e.g., super shoes) may place on sport rules. Kilian: IG: @runtoughmindset | Substack: https://substack.com/@runtoughmindset Sponsors: LMNT: https://drinkLMNT.com/HPO (free sample pack with purchase) deltaG: https://deltagketones.com Code: BITTER20 (20% Off) True Nutrition: https://truenutrition.com/hpo Code: HPO (20% Off) Episode Summary & Notes: Zach Bitter & Kilian Korth on PEDs, incentives, and doping in ultrarunning Context & framing Conversation is the third appearance by Kilian on Zach's podcast; shifts from traditional training/racing episodes toward current events in running. Sparked by recent doping-related controversies (Cam Hanes / Sage Canaday online conflict, Mike McKnight's discussion of BPC-157 use on Hanes' podcast). Both emphasize moving beyond narrow focus on specific peptides/cases to broader structural issues. Activism, incentives & tribalism Skepticism of modern activism: good causes often get distorted by perverse incentives (attention, platform growth, organizational self-preservation/mission creep). Online environments (especially short-form social media) reward polarization over curiosity or truth-seeking. Parallel drawn to low-carb diet advocacy: movement shifted from exploration of pros/cons toward dietary supremacy and identity attachment. Both hosts value changing one's mind with new evidence and prefer evolving conversations over tribal "debates" aimed at winning. Core problem in ultrarunning Rapid professionalization and financial incentives exist, but sophisticated testing (especially out-of-competition) is essentially absent. Honor-code system + high rewards creates conditions in which some athletes near the top are likely to use PEDs. Contrast with Olympic sports (e.g., swimming) where positives occur even with lower financial stakes. "Doping" is an unhelpful blanket term that equates intentional, high-impact cheating (e.g., EPO) with gray-area or accidental cases. BPC-157 and gray areas BPC-157 is an experimental peptide with very limited human data (one small study of 12 people among 36 total studies reviewed). Anecdotally has been used for tendon/muscle healing; on the WADA banned list at all times (no TUE pathway currently). Gray areas exist in WADA criteria themselves (performance enhancement potential, health risk, "spirit of the sport"). THC example: banned in-competition with a relatively high threshold; removed alcohol from the list is an example of changes over time. Distinction between letter of the rules vs. moral/cosmic fairness; between intentional advantage-seeking and medical/recovery use. Testing realities & practical challenges Full USADA/WADA-style regimes require whereabouts reporting, out-of-competition testing, and significant lifestyle constraints (conflicts with the free-spirited, remote nature of trail/ultrarunning). Even gold-standard systems have loopholes (missed whereabouts, remote camps, short-acting substances timed around sleep windows). Half-measures are expensive, burdensome, and unlikely to deter determined cheaters. Middle-of-pack and age-group athletes face different calculus; many use legitimate medications (inhalers, etc.) that may or may not require TUEs depending on type and dose/threshold. Possible paths forward discussed Transparency and honesty should be encouraged rather than punished (both hosts respect that Hanes and McKnight disclosed BPC-157 use). Practical ideas: Optional "non-competitive / open" checkbox so athletes using regulated substances can still participate without affecting results/records. Tested vs. non-tested divisions (bodybuilding-style model). More education needed around legitimate medical use (TUEs, Global DRO checks). Focus should prioritize the small professional/elite tier where financial and competitive incentives are highest over age-group minutiae. Future regenerative medicine and longevity interventions will force further adaptation; sport has already accepted large performance gains from technology (super shoes) more readily than internal/medical ones. Influencers & broader culture Influencer economy adds complexity: financial incentives to promote products or share experimental practices; difference between sharing personal experience vs. recommending use. Transparency with clear caveats is preferred; pure anecdote-driven advice remains problematic. Societal issues (tribalism, algorithmic incentives, low scientific literacy) make clean solutions difficult inside a small niche like ultrarunning. Closing notes Both stress nuance over black-and-white absolutism Conversation aims to push the sport toward honest discussion of incentive structures rather than endless case-by-case outrage. Kilian's Substack article ("The Run Tough Mindset") and upcoming documentary Forged in Failure are referenced as related material.
Break through your keto or low-carb plateau. Book a free call with Robert Sikes: https://www.ketobodybuilding.com/callThis man runs 200 miles on a low-carb diet, and his results challenge the high-carb rules of endurance racing. In episode 905 of the Savage Perspective Podcast, host Robert Sikes talks with ultrarunner Mike McKnight about keto endurance, fat adaptation, and ultramarathon fueling. Mike shares how eating more carbs led to swelling, water weight, stomach trouble, and uneven results. He explains why he returned to low-carb foods, electrolytes, and fasted training. They also cover his zero-calorie 100-mile run, the Tahoe 200 injury that sent him to the hospital, hydration, sodium, recovery, and the strategy needed to race for days. See why the best fuel plan may be personal.Follow Mike on IG: https://www.instagram.com/mikejmcknight/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - How a Tahoe 200 Head Injury Ended the Race4:00 - What 550 Racing Miles Did to His Legs6:08 - Why Mike McKnight Chose Italy After Tahoe 2008:14 - Why 200-Mile Races Favor Fat-Adapted Athletes10:20 - How Many Carbs Does an Ultramarathoner Really Need?14:17 - What Does a Low-Carb Ultrarunner Eat in a Day?16:50 - How Much Carbohydrate Do Endurance Athletes Eat?18:20 - Why Carbs Caused 8 Pounds of Water Weight20:28 - What Happens When You Run 100 Miles Fasted?25:39 - Do Ultramarunners Need Carbs for a Higher Gear?29:23 - Why Keto Endurance Fuel Is So Hard to Find32:09 - How to Balance Sodium, Potassium, and Water37:03 - Why 200-Mile Races Are a Strategy Game38:31 - How Do Backyard Ultras Work?41:54 - How to Choose the Right Trail Running Shoes44:21 - How Fatherhood Changes Extreme Endurance Racing48:38 - Why Truett Hanes Is Shaking Up Marathon Running50:37 - Why Cam Hanes' BPC-157 Use Sparked Backlash51:51 - How a Woman Broke the Cocodona 250 Course Record53:39 - Does VO2 Max Reveal Fat-Burning Efficiency?55:19 - Can You Keep Muscle While Training for an Ultramarathon?1:02:14 - Designing a Better Low-Carb Ultrarunning Fuel1:03:22 - How to Fuel an 800-Mile Arizona Trail FKT1:06:51 - Where to Follow Mike McKnight
Peptides are about so much more than GLP-1 weight loss. In this episode of The Women's Vibrancy Code, Maraya Brown explores peptide therapy, BPC 157, gut health, inflammation, anti-aging, brain health, and mood support, while sharing what to consider before adding peptides to your wellness journey and why working with a qualified practitioner matters. The Women's Vibrancy Accelerator Trifecta: Your 90-Day Health Reset Ready to take your health to the next level? The Women's Vibrancy Accelerator Trifecta offers deep, personalized support to help you regain control of your energy, hormones, and well-being. This program includes: Three one-on-one calls with Maraya Dutch Plus Test and full assessment Bi-weekly live Q&A sessions Self-paced health portal covering energy, hormones, libido, and confidence Podcast listeners get an exclusive discount. Use code PODCAST. Learn more and enroll now: https://marayabrown.com/trifecta/ _______________________ Free Wellness Resources Access free tools like the Menstrual Tracker, Adaptogen Elixir Recipes, Two-Week Soul Cleanse, Food Facial, and more. Download now: https://marayabrown.com/resources/ _______________________ Subscribe to The Women's Vibrancy Code Podcast Listen on Apple Podcasts, YouTube, and Spotify. _______________________ Connect with the Show Find us on Facebook, Linkedin | Website | Tiktok | Facebook Group _______________________ Apply for a Call with Maraya Brown Start your journey with personalized support. Apply here: https://marayabrown.com/call _______________________ About Maraya Brown Maraya is a Yale and Functional Medicine-trained Women's Health and Wellness Expert (CNM, MSN). She helps women feel energized, confident, and connected to themselves and their lives. With over 25 years of experience, she specializes in energy, hormones, libido, confidence, and deep transformation. _______________________ Disclaimer The content of this podcast is for informational, educational, and entertainment purposes only and does not constitute medical or professional advice. Listeners should consult with a qualified professional before making any health decisions. This Podcast Is Produced, Engineered & Edited By: Simplified Impact
Urologist Dr. Alex Tatum on Girth Enhancement, Testosterone, and Peptide Therapy Most men will never ask their doctor the questions this episode answers. From safe, non-surgical girth enhancement to daily testosterone dosing to the peptides fighting for FDA access right now, this conversation covers what actually works, what's dangerous, and what your doctor probably won't bring up first. Host Dave Asprey sits down with Dr. Alex Tatem, a board-certified urologist with fellowship training in male sexual and reproductive medicine. Dr. Tatem has built his practice and his YouTube following around pushing medicine beyond what the traditional medical establishment allows, with a focus on male girth enhancement, performance enhancement, peptides, and PEDs. They break down the real science behind penis enhancement, including why length surgery still does not exist, how hyaluronic acid injections safely increase girth, and why silicone and PMMA fillers have left men permanently disfigured. Dave and Dr. Tatem also get into cutting-edge testosterone dosing strategies, the peptides driving the biggest gains in human performance and longevity, including BPC-157, TB-500, SS-31, and MOTS-c, and why PT-141 has become the most talked-about peptide for libido and sexual health. You'll Learn: Why hyaluronic acid injections have become the safest, most reproducible method for girth enhancement The truth about penis enlargement surgery, and why length enhancement still has no reliable surgical fix How daily microdosed testosterone compares to traditional weekly TRT protocols Why PT-141 and melanotan II are being used for libido, nitric oxide release, and even prostate health How BPC-157, TB-500, SS-31, and MOTS-c are changing recovery, mitochondria function, and metabolism The dangerous enhancement trends to avoid, including silicone implants and unregulated fillers Why the fight over peptide access at the FDA could determine the future of functional medicine and supplements in America Thank you to our sponsors! - Just Thrive | Get a free 90-day supply of Digestive Bitters (a $90 value) when you start a 90-day Just Thrive Probiotic subscription at https://get.justthrivehealth.com/pages/asprey - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. - ALP | Head to http://alppouch.com/ and use code DAVE for 20% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: penis girth enhancement hyaluronic acid, penis enlargement that actually works, average penis size urologist, PT-141 for libido, melanotan II peptide, BPC-157 benefits, TB-500 for injury recovery, SS-31 dosing, MOTS-c peptide FDA, daily subQ testosterone dosing, oral testosterone undecanoate, TRT dosing protocols, Anavar for muscle recovery, silicone penile implant risks, PMMA filler complications, is penis enlargement surgery safe, hyaluronic acid girth injection cost, Dr. Alex Tatem urologist, peptides FDA regulation 2026 Resources: • Check Out Dr. Tatem's Content At: https://www.youtube.com/@DrAlexTatem • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 03:10 – Penis Enhancement Intro 13:32 – Dangerous Enhancement Methods 22:49 – Girth Procedure Explained 29:56 – Why Demand Is Rising 32:09 – Peptides for Men 41:26 – TRT and Testosterone 50:35 – Peptide Regulation Fight See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
July 28, 2026: Your daily rundown of health and wellness news, in under 5 minutes. Today's top stories: Throne raises $10M Series A to expand its AI-powered toilet sensor beyond gut health, betting the bathroom is the next frontier for passive diagnostics Nike and Hyperice unveil the Air Zoom Hyperslide, a recovery sandal with built-in heat and vibration therapy, embedding recovery into everyday footwear FDA advisory committee votes to recommend compounding six peptides including BPC-157 and MOTS-c, potentially creating a legal pathway out of the gray market Today's episode is brought to you by AIIR — a modern communications and experiential agency for health, wellness, fitness, and performance brands. From earned media to events and creator-led campaigns, AIIR helps companies sharpen their story, earn attention, and build trust that compounds. Visit https://aiir.agency to learn more. More from Fitt: Fitt Insider breaks down the convergence of fitness, wellness, and healthcare — and what it means for business, culture, and capital. Subscribe to our newsletter → insider.fitt.co/subscribe Work with our recruiting firm → https://talent.fitt.co/ Follow us on Instagram → https://www.instagram.com/fittinsider/ Follow us on LinkedIn → linkedin.com/company/fittinsider Reach out → insider@fitt.co
The FDA advisory committee voted July 23rd and 24th and social media has been running wild with the news, but most of what's circulating about BPC 157 and the other peptides that were on the agenda is either half-right or completely wrong. Inside today's episode, I break down what happened at the FDA's Widow campus in Silver Spring, what the 8 to 6 to 1 vote on BPC 157 means, and how to think about the timeline for legal access over the next 12 to 24 months. walk through the category one, two, and three interim policy that determines whether the FDA will take enforcement action during the rule making window, and more.Topics discussed: - The July FDA Advisory Committee Vote- The Seven Peptides on the Agenda- FDA Review Staff vs the Committee- The Research-to-Real-Use Mismatch- Section 503A and the Bulks List- Category One vs Category Two Policy- The 12 to 24 Month Access Timeline- State Medical Boards and Enforcement- What This Means for Health Coaches---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
In this episode the guys break down exactly how to pick the right workout for your goals — covering why enjoyment matters more than most people realize, how to honestly assess whether you actually like what you're doing, the ROI of strength training versus other modalities, and why appropriateness for your actual life is the deciding factor. They also get into the origin of clowns (spoiler: ancient India and Egypt, not the circus), the CLOW peptide stack from Vita Bella and why Sal and Katrina are both using it for recovery and skin health, Sal's revelation that he quit jiu jitsu because his ego got destroyed at a tournament in 2006 not because of scheduling, the Rafael Nadal documentary and what it teaches about identity and decline, and Carl Jung on why the back half of life is actually better than the first. Then they answer questions from Instagram on optimal body fat for women, how to increase maintenance calories without gaining fat, fixing forward rolled shoulders, and the ethical situations trainers face on the job. MAPS Upper Lower: https://mapsupperlower.com Code: LAUNCH for 40% off. Four day split, male and female versions, workout videos and live coaching with Cole. SPONSORS Vita Bella / MP Hormones: https://mphormones.com Book a complimentary 10-minute consultation with a membership specialist to find out if Vita Bella is right for you. CLO stack discussed on air (BPC-157, TB-500, GHK, CFPB) for recovery and skin health. Consultation: https://meetings-na2.hubspot.com/alever/marketing-membership-consultation Or use code MINDPUMP365 to start your annual membership and receive a free blood panel and gift. Paleo Valley (grass-fed fermented meat sticks): https://paleovalley.com/mindpump 15% off automatically applied at checkout. Four sticks a day = 24g protein at 280 calories. LMNT (electrolytes): https://drinklmnt.com/MindPump Free 8-count sample pack with any purchase. No code needed. New Lemonade Iced Tea flavor — 50mg caffeine, L-Theanine, polyphenols, no sugar. LINKS Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Intro 1:59 - How to pick the right workout for your goals 7:03 - Why people lie to themselves about what they actually enjoy doing 13:12 - How to find enjoyment in exercise when you hate everything 14:14 - How effective is the method for your goal — the ROI question 18:17 - What the right workout actually looks like for most people 24:35 - The Paleo Valley meat stick protein hack — 24g protein at 280 calories 26:23 - The origin of clowns — ancient India, Egypt and why they make the most in the circus 33:55 - CLO peptide stack from Vita Bella — Sal and Katrina's recovery and skin results 37:10 - Sal's real reason for quitting jiu jitsu — ego destruction at a 2006 tournament 46:53 - Rafael Nadal documentary — identity, decline and what happens after you peak 51:02 - Carl Jung on why the back half of life is better than the first 56:01 - Q&A: Optimal body fat percentage for women — and why chasing a number is the wrong approach 58:40 - Q&A: How to increase maintenance calories without gaining fat while cutting down cardio 1:01:24 - Q&A: Best movements to fix forward rolled shoulders 1:04:22 - Q&A: Ethical situations trainers face and how to handle them
Get personalized root-cause care with Empower Functional Health.Learn more at empowerfunctionalhealth.com_____Peptides are everywhere right now: VIP, KPV, BPC-157, TB-500, Thymosin Alpha 1, GHK-Cu, GLP-1s, and more. They are being talked about for inflammation, gut repair, immune support, tissue healing, weight loss, recovery, and chronic illness—but they are not automatically safe just because they sound “natural.”In this episode, Judy Cho breaks down what peptides are, why context matters, and the mistakes people may be making when they use them too casually or too early. Peptides can be powerful tools, but the wrong peptide, timing, or source can pose risks most people are not considering.What are peptidesVIP (Vasoactive Intestinal Peptide)KPVBPC-157TB-500, Thymosin Beta-4 (Wolverine Stack)Thymosin Alpha 1, Mots-CGHK-CuGLP-1s, natural peptides, 3D GLP1s, Peptide risk nuance and examplesPeptide grey market risksFour tactical peptide considerations_____EPISODE REFERENCESNwJ Peptide ArticleTaking VIP Too Early Copper ToxicityPeptide Contamination: 1, 2_____WEEKLY NEWSLETTER
Andrew Huberman, Ph.D., is a neuroscientist and tenured professor in the Departments of Neurobiology and Ophthalmology at Stanford University School of Medicine, where he runs the Huberman Lab. He is the author of Protocols: An Operating Manual for the Human Body.This episode is brought to you by:ProLon science-backed Fasting Mimicking Diet that helps activate cellular renewal through fasting, while still eating nourishing mealsEight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heatingMomentous high-quality creatine for cognitive and muscular supportHelix Sleep premium mattressesTimestamps:00:00:00 — Who is Dr. Andrew Huberman?00:02:03 — Dean Potter, The Dark Wizard, and the physics of raw energy.00:04:11 — Why competition destroys performance.00:05:45 — Laird Hamilton, tow-in surfing, and the lure of big waves.00:06:27 — Training with Dorian Yates.00:18:29 — The full weekly split that keeps building strength at 50.00:21:00 — Neck training.00:25:56 — AssaultBike vs. Airdyne.00:31:12 — Revisiting MDMA and psychedelics.00:48:06 — Inducing plasticity is only half the job.00:53:17 — The one-day protocol that cut my anxiety by 90%.01:00:27 — Cortisol as the master key.01:03:26 — Peptides demystified: GLP-1s, growth hormone, and BPC-157.01:14:44 — The Enhanced Games, the Deca burrito, and the honesty problem.01:17:56 — Pinealon, epitalon, and the hunt for more REM sleep.01:25:02 — Why women, not gym bros, are the real peptide market.01:35:52 — Why "no reported side effects" is a trap.01:43:48 — Stem cells, cartilage regrowth, and mining the body for medicine.01:46:37 — AI, wearables, and the race to write to the nervous system.01:54:12 — The MIT mask that puts you to sleep in six minutes.01:56:09 — Inside Andrew's new operating manual, Protocols.02:03:30 — Navigating grief and remapping loss.02:04:40 — Shut up, suit up, show up.02:08:03 — Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This podcast is made possible by our listeners and viewers. If this show has brought you value, you can support it by becoming a member of The Way Forward, our platform designed to help you find the health and freedom community (people, practitioners, schools, farms, and more) near you. Your membership directly supports the podcast and the work we do.Get 10% off your Heart & Soil order with code THEWAYFWRD at checkout. Shop Heart & Soil here!There's a version of health optimization that's making people more anxious, more neurotic, and less resilient, and almost no one in the space is willing to call it out.The holistic health space has a problem, and Ste Lane is one of the few people naming it. He's a coach, homesteader, and host of Radical Health Radio. His lens on ancestral health, masculinity, and human vitality is shaped by everything from cage fighting in England to raising kids on the land in Tennessee.Ste and I have been orbiting each other's worlds for years, and this conversation is the first time we've been able to sit down and dig in.A lot gets covered, but the real thread underneath is this: most people are outsourcing their health to protocols, supplements, peptides, and fear-based content, and it's making them weaker, not stronger. Ste has strong things to say about why the vaccine was never actually forced, why orthorexia is subtly wrecking people, and what the wellness industry keeps getting wrong about resilience.We also get into his four-truths framework, what real success looks like, and why the emotional and spiritual side of health matters more than the biohacks.You'll Learn:[0:00] Introduction[7:07] Mark Sisson's podcast and the virtue of restraint[24:47] Falling for Nicole and an Indonesian village that broke his brain about success[43:26] Success is getting what you want, and how Ste defines it now[1:01:38] The wellness space has become a mess of overwhelm and fad chasing[1:20:14] Blaming outside forces for sickness is weakness, plus the peptide and vaccine hypocrisy[1:32:03] BPC-157 healed his meniscus tear, and how health comes down to four simple truths[1:56:30] Working in versus working out, and why mobility is real estate you already own[2:25:22] Heart and Soil's origin story, and a Bulgarian textbook smuggled out for cigarettes[2:42:59] A Parkinson's neighbor whose tremors calmed within days of eating brain tissue Related The Way Forward Episodes:The 4th Phase of Water: The Blueprint for Biological Energy with Dr. Gerald Pollack | PodcastResources Mentioned:The Law of One by Ra | Books The Red Lion by Maria Szepes | BookFind more from Ste:Ste Lane | InstagramRadical Health Radio | Website | Instagram | YouTubeHeart and Soil Supplements | Website | Instagram | YouTubeFind more from Alec:Alec Zeck | Instagram | XThe Way Forward | InstagramDonate to The Way Forward here.The Way Forward is Sponsored By:BEAM Minerals: Feel the Difference in Days: Join thousands recharging with plant-based minerals. Click here for 20% Off Your First Bottle of BEAM.Want to grow your podcast but not sure what's actually working? Podigy helps me produce The Way Forward. Take their free assessment to get clear on your next move—and a chance to win a call with their founder.Eating well shouldn't be complicated. Dr. Cowan's Garden makes it simple to increase your daily nutrient density with their signature vegetable powders, clean pantry staples, and pasture-raised products. Family-run and committed to "beyond-organic" quality.* Offer: Use code THEWAYFORWARD for 15% off your first order.* Shop: Dr. Cowan's Garden
Chalene Johnson breaks down retatrutide, the peptide everyone is calling a GLP-3 and an Ozempic killer, cutting through the hype to get to what the science actually says. Eli Lilly's own clinical trials show weight loss results that beat anything semaglutide or tirzepatide has produced, but retatrutide is not FDA approved and is not legally available at any US pharmacy, which means almost nobody buying it online is actually getting the real thing. Chalene explains what retatrutide actually is (a triple agonist that adds glucagon receptor activity to the GLP-1 and GIP receptors already targeted by Ozempic, Wegovy, Mounjaro, and Zepbound), walks through what the phase three trial data really shows versus how it is being exaggerated online, and shares why an independent lab test of vials sold through TikTok, med spas, and Reddit found most contained only 7 to 14 percent of anything resembling the real molecule. She also unpacks the muscle preservation claims that are not backed by human data, the anhedonia and placebo effect reports circulating online, why bariatric surgery comparisons need context, and how to find a reputable source like Midi Health for anyone considering a GLP-1 through legitimate medical channels. Topics discussed: retatrutide, Ozempic, semaglutide, Wegovy, tirzepatide, Mounjaro, Zepbound, GLP-1, GLP-3, Eli Lilly, bariatric surgery, Midi Health, anhedonia, muscle wasting, peptides, BPC 157 Go Beyond The Podcast Join Chalene on her private podcast
Why Oral and IV Glutathione Never Actually Reach Your Cells (The Delivery Breakthrough Changing Everything) Most of the supplements you're taking aren't failing you, they're failing to ever reach the cells that need them, and almost nobody selling them wants you to know that. This episode hands you the delivery breakthrough that actually gets it there. Use code DAVE for a discount at aurowellness.com/dave Host Dave Asprey sits down with Dr. Nayan Patel, a pharmacist, researcher, and founder of Auro Wellness, whose work centers on solving one of biohacking's most stubborn problems: getting nutrients past the bloodstream and into the cells that actually need them. He holds 14 patents in delivery technology, partners in the high-end longevity clinic Unlimited Life, and has spent over two decades studying glutathione, the master antioxidant his own research helped bring into modern biohacking. Dave and Dr. Patel break down a 2011 University of Texas study showing that oral and liposomal glutathione are completely broken down into raw amino acids before absorption, meaning none of it reaches the bloodstream as glutathione, a pattern that holds true even for IV administration. They dig into new brain-imaging research showing topical glutathione crossing into neural tissue within 20 minutes, why senescent "zombie cells" may be directly tied to glutathione shortfalls, and why NAD, despite its reputation as the ultimate longevity molecule, is actually dependent on glutathione to do its job. They also cover the real purity ceiling on GHK-copper peptides, safe upper limits for glycine and NAC before they start working against you, a topical alcohol protocol that clears acetaldehyde without triggering a breathalyzer, and why oxidative stress from GLP-1 use is quietly driving one of the drug class's least-discussed side effects. You'll Learn: Why oral, liposomal, and even IV glutathione never actually reach your cells intact, and what a 2011 UT study proved about it How topical glutathione was shown to cross into brain tissue within 20 minutes, and what that means for neurological aging Why senescent "zombie cells" may be directly linked to glutathione shortfalls, and how one longevity clinic reversed markers by 70% in a year Why NAD isn't the "ultimate longevity drug" it's marketed as, and its actual dependent relationship with glutathione The real purity ceiling on GHK-copper peptides, and why 73% is currently the best available anywhere Safe upper limits for glycine and NAC, and the oxalate crystal and Parkinson's-like risks of overdoing either one A topical alcohol protocol that clears acetaldehyde fast enough to beat a breathalyzer Why GLP-1 drugs are quietly driving oxidative stress, and what most patients are missing to counter it Thank you to our sponsors! - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. - OneSkin | Get 15% off OneSkin with the code DAVE at https://www.oneskin.co/DAVE #oneskinpod - Caldera + Lab | A small habit with big results. Go to CalderaLab.com/DAVE and use code DAVE for 20% off your first order. - Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com and using code DAVE at checkout Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: glutathione, Nayan Patel, Ora Wellness, glutathione absorption, transdermal delivery, senescent cells, zombie cells, cellular aging, GHK-copper peptide, NAD, NAD supplements, NAC, glycine, GlyNAC, oxalate crystals, alcohol metabolism, acetaldehyde, GLP-1, semaglutide, oxidative stress, heavy metal detox, mercury toxicity, BPC-157, biohacking, longevity, functional medicine Resources: • Get A Discount On Auro Wellness Products - Use code DAVE: aurowellness.com/dave • Learn More About Dr. Patel's work at: http://aurowellness.com/dave• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/davetube • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:43 – Episode Intro 03:16 – Glutathione Basics 07:34 – Senescent Cells 11:07 – Cellular Delivery Science 14:20 – GlyNAC Precursors 21:37 – Amino Acid Ratios 25:18 – GHK Copper Peptide 28:41 – Purity & Manufacturing 31:34 – Glutathione vs. NAD 33:49 – Absorption Studies 37:51 – Heavy Metals & Toxins 42:35 – Alcohol & Glutathione 47:43 – Mortality & Reincarnation 49:54 – GLP-1s & Anhedonia 53:25 – Future of Peptides See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.