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Is modern wellness actually making us healthier... or just more anxious? Are peptides like BPC-157 and TB-500 safe? Can I be aroused if I have low libido? Double board-certified physician associate Ashley Madsen is here to give one of the most refreshingly honest conversations on modern health, longevity, hormones, peptides, nervous system regulation, and the growing culture of optimization. She explains why social media has turned wellness into a full-time job, why personalized medicine matters more than following influencers, and why emotional health may be the missing foundation beneath nearly every aspect of physical performance. Ashley also delivers one of the clearest explanations you'll hear on peptides like BPC-157 and TB-500, hormone replacement therapy, libido as a vital health marker, wearable technology, nervous system regulation, nitric oxide, cardiovascular health, and why many people are chasing expensive biohacks while neglecting the fundamentals that truly move the needle. Follow Ashley @ashleymadsenofficial Follow Chase @chase_chewning ----- 00:00 Intro 00:03 Welcome Ashley Madsen 01:12 Is the Wellness Industry Making Us Less Healthy? 06:36 The Morning Habit That Changes Everything 09:32 Is Wellness Just Masked Insecurity? 14:19 Sponsor: KetoneIQ 15:38 Sponsor: 38TERA Gut Health 17:05 Are Hormones Really the Problem? 21:03 Why More Lab Testing Isn't Always Better 24:12 The Truth About Peptides 28:57 BPC-157 Explained 36:50 How Long Does BPC-157 Actually Take to Work? 40:18 How to Buy Peptides Safely 44:05 What Does "Regulating Your Nervous System" Actually Mean? 47:32 Ashley's Favorite Stress-Reduction Tools 52:18 Why Libido Is One of Your Most Important Health Markers 56:20 Erectile Dysfunction Could Predict Heart Disease 01:00:19 How Often Should Healthy Couples Have Sex? 01:03:18 Nitric Oxide, Blood Flow & Longevity 01:05:18 Why Women Need Estrogen 01:07:30 Most Overrated Wellness Trend of 2026 01:10:20 The Most Underrated Habit for Better Health 01:10:33 One Supplement You're Probably Wasting Money On 01:12:25 The First Thing Everyone Should Do Every Morning 01:14:08 What Does "Ever Forward" Mean to Ashley? ----- Episode resoures: EnergyBits - Support cellular energy naturally with algae packed full of bioavailable nutrients. Save 20% using code EVERFORWARD at https://www.EnergyBits.com KetoneIQ - Support mental clarity, focus and sustained energy with ketone shots. Save 30% at https://www.Ketone.com/chasechewning 38TERA - Science-backed gut health support formulated with Dr. Will Bulsiewicz. Save 33% on your first order at https://www.38Terra.com/everforward
What if the goal isn't just living longer, but feeling vital the whole way through? Peptides have jumped from the fringe to the mainstream, and most of what you'll find online comes from dubiously credentialed sources. In this episode, Jeff sits down with Dr. Aleksandra Gajer, an emergency medicine physician who spent a decade in the ER before founding The Gajer Practice and moving into longevity and regenerative medicine. They unpack what peptides really are and how to think clearly about a fast-moving, lightly regulated space. The conversation covers: What peptides actually are, and why insulin and GLP-1s belong to the same family BPC-157 and TB-500 for healing tendons, ligaments, and stubborn injuries Growth hormone-promoting peptides like sermorelin and tesamorelin for muscle and body composition The gray market, compounding pharmacies, and the FDA's shifting rules Cancer risks, contraindications, and who should be cautious This episode is for anyone curious about peptide therapy, longevity, and healing who wants grounded information instead of internet hype. Learn more about Dr. Aleksandra Gajer and The Gajer Practice at thegajerpractice.com. The practice offers telemedicine consultations nationwide, plus a course for clinicians who want to integrate peptides into their work (found in the About section of the site). Follow along on Instagram: @thegajerpractice LMNT: Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 25% off your order at vivobarefoot.com/commune. CocoaVia:. Use code COMMUNE2026 for 25% off at CocoaVia.com
Curious whether peptide therapy is the missing piece in your wellness routine, or just another overhyped trend? This episode breaks down what these powerful chemical messengers do in the body, from healing injuries to balancing brain chemistry, cellular energy and more, plus why sourcing and dosing make all the difference.Host Jenn Trepeck sits down with Dr. Aleksandra Gajer to explore BPC 157, brain-supporting peptides, and mitochondrial function, while tackling how to use peptides safely, who should avoid them, and why they work best as a tool rather than a magic fix-all.What You Will Learn in This Episode:✅ How peptide therapy acts as a chemical messenger system that supports the body's own healing pathways rather than overriding them✅ Why BPC 157 has become one of the most talked about peptides for tendon repair, gut healing, and recovery✅ How neuroinflammation, not just neurotransmitter imbalance, may be driving anxiety, depression, and brain fog✅ The role of mitochondrial function and insulin sensitivity in body composition, energy, and long-term metabolic healthThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Dr. Aleksandra Gajer's path from emergency medicine to proactive, personalized healthcare08:04 Defining peptides and their relationship to inflammation and healing10:04 Exploring BPC 157 for tendon injury, gut healing, and tissue recovery12:31 How peptides support autoimmune conditions by regulating immune balance15:35 Brain peptides Selank and Semax and the truth behind the neuroinflammation link to anxiety18:57 Understanding mitochondrial function, fatigue, and brain fog as cellular energy issues20:35 MOTS-c, insulin sensitivity, and the connection to body composition22:18 Why peptides work best as a tool, not a replacement for healthy habits26:03 Safe peptide sourcing, endotoxins, and who should avoid peptide therapy33:54 Hormone health, dosing strategy, and cycling peptides for sustainable resultsKEY TAKEAWAYS:
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Dr. Nick Norwitz lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Dr. Nick Norwitz believes is coming in Alzheimer's gene therapy within the next decade. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The ApoE4 Paradox and the Case Report That Broke the Internet (00:00:57) Why Standard Omega-3 Supplements Fail and What to Take Instead (00:05:13) DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier (00:10:19) ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic (00:17:38) Why ApoE4 Carriers Burn Through DHA Faster and Need More (00:20:31) Women, Omega-3s, Menopause, and Brain Insulin Resistance (00:21:41) Statins, Sex Differences, and the DHA-Blood Sugar Connection (00:26:01) Statins and Dementia: What the Data Actually Say (00:32:24) Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology (00:42:19) The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance (00:45:21) Gene Editing, Prime Editing, and the Future of ApoE4 Therapy (00:49:33) Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data (00:55:10) The EZPAVE Trial: Why the Headlines Don't Hold Up (01:00:33) KetoneIQ: Ketones for Brain Energy and Focus (01:01:29) Cheers Health: Supporting Liver Function and Cognitive Recovery (01:03:54) If Not LDL, What Causes Heart Disease in Metabolically Healthy People? (01:12:05) The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism (01:19:10) Ketones, Women's Brains, and Clearing Misfolded Proteins (01:21:08) The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More (01:24:01) GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau (01:25:28) Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching (01:29:02) Why Nick Is Controversial And Why He Doesn't Mind _______ *Thank you to our sponsors*Fenix Health Science: fenixhealthscience.com Use code NEUROEXPPulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your orderFunction Health: https://www.functionhealth.com/louisanicolaBASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% offKetoneIQ: https://ketone.com/NEURO for 30% OFFCheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Nick lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Nick believes is coming in Alzheimer's gene therapy within the next decade. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The ApoE4 Paradox and the Case Report That Broke the Internet 00:57 Why Standard Omega-3 Supplements Fail and What to Take Instead 05:13 DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier 10:19 ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic 17:38 Why ApoE4 Carriers Burn Through DHA Faster and Need More 20:31 Women, Omega-3s, Menopause, and Brain Insulin Resistance 21:41 Statins, Sex Differences, and the DHA-Blood Sugar Connection 26:01 Statins and Dementia: What the Data Actually Say 32:24 Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology 42:19 The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance 45:21 Gene Editing, Prime Editing, and the Future of ApoE4 Therapy 49:33 Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data 55:10 The EZPAVE Trial: Why the Headlines Don't Hold Up 01:00:33 KetoneIQ: Ketones for Brain Energy and Focus 01:01:29 Cheers Health: Supporting Liver Function and Cognitive Recovery 01:03:54 If Not LDL, What Causes Heart Disease in Metabolically Healthy People? 01:12:05 The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism 01:19:10 Ketones, Women's Brains, and Clearing Misfolded Proteins 01:21:08 The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More 01:24:01 GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau 01:25:28 Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching 01:29:02 Why Nick Is Controversial And Why He Doesn't Mind _______ Thank you to our sponsors Fenix Health Science: fenixhealthscience.com Use code NEUROEXP Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Function Health: https://www.functionhealth.com/louisanicola BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off KetoneIQ: https://ketone.com/NEURO for 30% OFF Cheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Leveling Up: Creating Everything From Nothing with Natalie Jill
What if the supplements you've been taking to feel better are actually the reason you feel worse? That's exactly what happened to me, and it sent me down a rabbit hole that led to one of the most important conversations I've had about my own health. Today I'm sitting down with my close friend and personal doctor, Dr. Sabrina Solt, a regenerative medicine physician and peptide expert who has been in this field for over a decade. We start with the question that started everything for me: why was I wired at 3am, crashing every afternoon, and reacting to the exact supplements I thought were helping? Dr. Solt breaks down the cortisol-prolactin connection that most doctors never test for, explains why elevated cholesterol in midlife women is often a protective response rather than a red flag, and walks us through the inflammation markers that actually tell the full story of what's happening inside the body. Then we go deep on what she calls the upstream-downstream problem, the real reason why things like methylated B vitamins, NAD drips, and glutathione pushes can backfire so badly in certain women, and what to do instead. She explains the genetic piece around MTHFR and COMT variations, why "more" is rarely the answer, and what supporting downstream clearance actually looks like in practice. From there, we get into peptides. Dr. Solt gives a grounded, clinical breakdown of BPC-157, TB-500, KPV, the copper peptide GHKCU, growth hormone releasing peptides, and the serious cautions around GLP microdosing gone wrong. She also shares her vision for what medicine could look like if doctors were equally fluent in peptides and pharmaceuticals. This is the conversation I've been wanting to bring to you for a long time. Dr. Sabrina Solt is one of the most precise and brilliant minds I know, and she does not hold back. WE GO DEEP ON: The cortisol-prolactin connection most doctors never test Why high cholesterol isn't always the villain (and what MPO reveals) The upstream-downstream mistake making "healthy" habits backfire Why NAD and glutathione drips can be dangerous for some people A no-BS peptide breakdown: BPC-157, TB-500, KPV, copper peptides, and more The truth about GLP microdosing and its risks What to fix before you ever try a peptide Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube Learn More About Sabrina Solt Instagram ➜ http://www.instagram.com/drsolt Website ➜ http://www.stemcelltherapypro.com/ Peptide Membership Website ➜ https://dr-solts-peptide-corner.circle.so/forms/dfdcc2cd Thank you to our show sponsors: QUANTUM UPGRADE: Try Quantum Upgrade completely free for 15 days—no credit card required. Use code NATALIEJILL at checkout on https://quantumupgrade.io/start TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit For advertising inquiries: https://www.category3.ca/ Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.
The Thought Leader Revolution Podcast | 10X Your Impact, Your Income & Your Influence
"People who are excited about aging live seven and a half years longer than people who aren't." JJ Virgin is one of the most recognizable names in health, nutrition, and wellness entrepreneurship — a four-time New York Times bestselling author and the founder of two distinct businesses: one aimed at consumers through her Well Beyond 40 platform, and one aimed at healthcare practitioners through the Health Business Growth Collective. She joins Nicky for a conversation that moves fast and covers a lot of ground. The central thread running through everything is the belief — supported by research Virgin cites and by decades of watching people age well or poorly — that the story you tell yourself about getting older shapes the biological reality of it. The entrepreneurs and practitioners who stay sharp, vital, and relevant into their sixties and seventies tend to share one thing: it doesn't dawn on them to act old. They keep seeking challenge, keep falling in love with what they are learning, and refuse to accept that the best chapters are behind them. The conversation goes deep on the emerging science of peptides and regenerative medicine — two fields that Virgin believes are on the verge of becoming mainstream, and two fields that face meaningful resistance from the pharmaceutical industry. She explains what urolithin A, BPC-157, and regenerative biologics like exosomes and PRP actually do, why compounding pharmacies are more rigorously monitored than most people assume, and how this science first came onto her radar when her son was fighting for his life after a near-fatal accident. There is also a strong thread on sales and business — Virgin's argument that selling is a moral responsibility, not something to avoid, and what happens when healthcare practitioners treat their discomfort with sales as a virtue rather than a liability. JJ closes with three concrete steps anyone can act on immediately — none of them require a gym membership, a supplement budget, or a complete business overhaul. Expert Action Steps: 1. Move intentionally every single day. Daily movement is not optional maintenance — it is the most powerful tool available for extending both health span and mental sharpness. 2. Keep learning and seek out discomfort. Look specifically for challenges that force you to adapt — whether that is lifting heavier, taking on a new skill, or entering a room where you are the least experienced person. 3. Choose your thoughts about age and possibility with deliberate care. The research suggests that how you feel about aging shapes how you age. Decide who you want to be physically and mentally, and orient your daily choices around that version of yourself. Learn more & connect: JJVirgin.com Well Beyond 40 podcast — available on all major platforms Health Business Growth Collective — https://thehbgc.com/ Health Business Growth Show — available on all major platforms Resources mentioned: The Virgin Diet by JJ Virgin — JJVirgin.com The Sugar Impact Diet by JJ Virgin — JJVirgin.com Understanding Women by Alison Armstrong — allisonarmstrong.com Urolithin A / Timeline — timelinenutrition.com BPC-157 — available through compounding pharmacies; consult a functional medicine practitioner Visit https://www.eCircleAcademy.com and book a success call with Nicky to take your practice to the next level.
Peptides are being sold online as miracle fixes for energy, healing, and longevity—but what if the science behind them is shaky, or even dangerous? In this episode, Therese Markow and Dr. Leigh Baxt pull back the curtain on the peptide craze, revealing what we really know (and don't know) about these heavily marketed "biohacks." They discuss the complexities and risks of unapproved peptides, which are often marketed for health enhancement. Dr. Baxt explains what peptides are and speaks to those drugs that are FDA-approved, like GLP-1 agonists and insulin, but also highlights the safety concerns of unapproved peptides, such as BPC-157 and TB-500, which lack appropriate clinical trial data and are often synthesized in unregulated labs. Dr. Baxt emphasizes the importance of proper clinical trial processes and regulatory oversight to ensure drug safety and efficacy. Key Takeaways: A peptide is just a short chain of amino acids. They can be created synthetically, they can be isolated, and they are natural. The body doesn't care whether a peptide is "natural" or synthetic; what matters is its exact molecular structure. FDA-approved peptide drugs go through years of rigorous testing in animals and humans to prove both safety and effectiveness before reaching the market. Calling something "scientifically proven" can be misleading when the underlying evidence is weak, preliminary, or based only on rat studies. Especially as much of the "science" cited on peptide marketing sites comes from small, limited animal, or cell studies, not large, controlled human trials. Just because a product is available online or from a compounding pharmacy does not mean it is FDA-approved, well-studied, or safe; consumers must look beyond hype and ask what evidence truly exists. A naturally occurring peptide is generally not going to be suitable for use therapeutically. "You can say that something is scientifically demonstrated because it showed something interesting in a rat. The key is that the people may not ask that, because a lot of times people hear 'scientific terminology' and it makes something sound really legitimate, but it doesn't mean that there's solid data." — Dr. Leigh Baxt Evaluation of Research Grade Peptides Marketed Directly to Consumers Reveals Extensive Variability in Purity and Measured Abundance: https://www.preprints.org/manuscript/202604.1748 Connect with Dr. Leigh Baxt: Professional Bio: https://www.mskcc.org/profile/leigh-baxt LinkedIn: https://www.linkedin.com/in/leigh-baxt-314b877 Connect with Therese: Website: www.criticallyspeaking.net Bluesky: @CriticallySpeaking.bsky.social Instagram: @criticallyspeakingpodcast Email: theresemarkow@criticallyspeaking.net Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.
Peptides are everywhere right now. From social media influencers and wellness clinics to fitness circles and longevity enthusiasts, they're being marketed as the next big thing for recovery, muscle growth, anti-aging, and optimization. But what does the science actually say?In this episode, we sit down with Leigh Baxt, PhD, with nearly two decades of experience in translational science and drug development, to unpack the growing peptide trend. We discuss how drugs are actually developed, why most therapeutic ideas fail, the difference between FDA-approved peptide medications and unregulated compounds, and how marketing often outpaces evidence. If you've ever wondered whether peptides like BPC-157 or TB-500 are worth the hype, this conversation will help you separate science from salesmanship."If something sounds too good to be true, it probably is."- Leigh Baxt, PhD“When you do science, the experiments you design are the ones to try to poke a hole in your hypothesis."- Leigh Baxt, PhDThis week on Capable & Worthy: Fitness, Nutrition and Mindset for People Who Don't Want Life to Suck:Why more than 99% of potential drug therapies never make it to marketWhat translational science is and how new therapies are developedThe difference between FDA-approved peptide drugs and unregulated peptidesWhy peptides like BPC-157 and TB-500 raise concerns among scientistsThe role of human clinical trials in determining safety and effectivenessHow marketing language can make products appear more evidence-based than they areWhy women in midlife may be especially vulnerable to peptide marketing claimsHow to evaluate health claims critically and find trustworthy scientific information Connect with Leigh Baxt, PhD: Leigh Baxt, PhD on Instagram - sciencemomscicommThanks for tuning in to this week's episode of Capable & Worthy: Fitness, Nutrition, and Mindset for People Who Don't Want Life to Suck, where we challenge the common understanding of what it means and what it takes to be fit and healthy! If you enjoyed this episode, don't forget to subscribe and leave a review wherever you listen to your favorite podcasts.Apple Podcasts | SpotifyBe sure to share your favorite episodes on social media and tag us!Join Iris Deadlifts on Instagram and Amy Rudolph on Instagram.
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksBPC-157 is the peptide almost everyone starts with. In this masterclass I walk through why, and where the hype gets ahead of the evidence.We have about 30 years of animal studies on this one. We have fewer than 30 human subjects in published research. I keep that line clear the whole way through.I cover what BPC actually does. It helps the body repair tissue. It works on the gut, tendons, ligaments, and even the brain in animal models. It is not a steroid and it does not build muscle on its own. I explain how it works, who it helps, and who should skip it.Then we get practical. Dosing tiers, how to reconstitute the vial, how to inject near an injury, and how long before you feel anything.I tackle the cancer question head on. The fear is plausible on paper. The data does not really back it up. I tell you exactly where I land.We also cover cycling, the Wolverine stack with TB-500, oral versus injectable, and the FDA shift happening right now.Even if you already know this one, you will probably pick up something. If you are new to peptides, start here.
I'm joined by Dr. Lauren Colenso-Semple to unpack the rapidly growing world of wellness peptides — from BPC-157 and CJC-1295 to Ipamorelin, Tesamorelin, NAD, and the so-called “fat-burning” and “healing” peptides taking over social media. We discuss what peptides actually are, why they've become so popular, and how legitimate medical therapies have blurred into a largely unregulated wellness industry.We also break down the claims being made about popular peptides marketed for fat loss, recovery, anti-aging, and performance enhancement, while taking a closer look at what evidence truly exists (and what doesn't). Dr. Lauren shares important insight into the safety concerns, marketing tactics, and cultural obsession with optimization that are fueling this trend online.If you've been curious about peptides or wondering whether the internet hype matches the science, this episode will help you think more critically before jumping on the trend.Check out Dr. Lauren Colenso-Semple's work here: https://www.drlaurencs.com/
This week is a Q&A episode in two parts. In Part 1, I give you the honest, real-numbers breakdown of the four Central American countries we keep weighing for our family: Nicaragua, Costa Rica, Panama, and Mexico. Rent, nannies, food, healthcare, schools, and flights from Canada. In Part 2, I answer three of the peptide questions you sent me: the Wolverine blend for an ACL tear, Selank vs psilocybin microdosing, and whether GHK-Cu actually works in a body cream. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. Timestamps: 04:00 - The four-country comparison framework 08:00 - Nicaragua, San Juan del Sur 13:00 - Costa Rica, Guanacaste (Tamarindo, Nosara) 19:00 - Panama, the underrated dark horse 24:00 - Mexico, Riviera Maya (Playa del Carmen, Puerto Aventuras) 30:00 - Side-by-side comparison: rent, nanny, healthcare, schools, food, flights 36:00 - Wolverine blend for ACL tear (BPC-157 + TB-500, blends vs. singles) 47:00 - Selank vs. psilocybin microdosing 58:00 - GHK-Cu body cream: does it actually work? 01:12:00 - Recap and where to go from here Resources: My trusted Peptide Source Guide. Work with me one-on-one. The Her Stack Planner. Join The LongHer Life. Let's connect: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music Disclaimer: I am a Registered Holistic Nutritionist and educator, not your physician, nothing here is medical advice.
In this episode, Brent speaks with physician-scientist Dr. Loren Walensky to explore the rapidly growing world of peptides, GLP-1 drugs, and experimental health interventions. As compounds like semaglutide, BPC-157, and other peptides gain popularity in wellness and longevity circles, Walensky explains the critical difference between therapies that have been rigorously tested and those that are being used long before the science is settled. The conversation covers obesity, willpower, off-label prescribing, the role of the FDA, and why promising treatments still need evidence before they can be considered safe and effective. He's as credentialed as you can get on this topic, hope you enjoy.
If you've spent any time on social media or in many gyms lately, you've probably heard the buzz about BPC-157. Often called the "healing peptide," it's being touted as a miracle cure for everything from chronic tendinopathy to acute muscle tears. Patients are showing up in our clinics asking where they can get it, and some "wellness clinics" are already handing out injections like candy.But as sports physical therapists, we have to look past the "bio-hacker" headlines and look at the hard data. Is there actually any human evidence that this works? And more importantly, is it even legal for your athletes to use?A brand-new systematic review just hit the journals, and it's the most comprehensive look we've seen yet at the mechanism, the MSK outcomes, and the massive safety "gray areas" surrounding this compound. The results are fascinating, but they come with some major red flags that every clinician needs to hear before their next patient interaction.In this week's episode, I'm diving deep into the science of BPC-157. We're breaking down the pathways it uses to (potentially) speed up tissue repair, the truth about the current human research, and the legal warnings you must give your athletes to protect their careers.To see full show notes and more, head to: https://mikereinold.com/the-truth-about-bpc-157-peptide-in-sports-medicine-what-you-need-to-know/Learn our proven system for sports PTs who want to master ACL rehab, confidently progress patients, and guide athletes safely back to high-level sport.Click here to learn more Click Here to View My Online CoursesWant to learn more from me? I have a variety of online courses on my website!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the show_____Want to learn more? Check out my blog, podcasts, and online coursesFollow me: Instagram | Twitter | Facebook | Youtube
Dr. Spencer Nadolsky and Karl bring on Dr. Austin Baraki and Dr. Jordan Feigenbaum from the Barbell Medicine crew for a conversation that cuts through one of the most hyped and least understood topics in the health and fitness space right now: the research peptides that millions of people are injecting into themselves based on anecdotes, social media marketing, and the logic that short chain amino acids are natural so they must be fine. In this episode they cover what peptides actually are from a basic biochemistry standpoint and why calling something a short chain amino acids does not make it a food or a supplement it makes it a drug with all the same questions around safety efficacy dosing and long-term effects that any other drug requires, why the explosion of GLP-1 popularity essentially normalized both injectable medications and the idea that if semaglutide works this well what else is out there leading directly to the current peptide boom, why BPC-157 has no randomized controlled trial data in humans and the three human trials that were started were all terminated early with results never published which is a red flag that would make people furious if it were a vaccine but barely registers in the peptide space, why TB-500 has wound healing data when applied topically but nothing when injected despite being universally marketed as a muscle and tendon healer, why MOTS-C has never been tested in humans at all and yet enormous numbers of people are currently injecting it, why the argument that big pharma would sell these if they worked is actually the correct argument and why most of these compounds were abandoned precisely because they failed in trials or showed harm signals, why biological plausibility is a dangerous standard to rely on given that suppressing arrhythmias seemed biologically obvious until the CAST trial showed it killed people and beta blockers for heart failure seemed obviously wrong until trials showed they were life saving, what a randomized controlled trial actually does that anecdote cannot and why thousands of positive experiences are not equivalent to controlled data, why a JAMA study on SARMs sold as research chemicals found that only 18 of 44 products actually contained what was on the label meaning people may not even be getting the compound they think they are getting, why the doctors on this podcast could have made millions of dollars branding and selling their own peptide lines and have specifically chosen not to, and what standard of evidence they believe should be the minimum before recommending any compound to another human being. The Docs Who Lift podcast distills and simplifies the complexities of exercise, medicine, and weight loss. Subscribe so you never miss an episode. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Send us Fan MailLISTENER DISCRETION: The views and opinions Mark shares on this podcast are his own and do not necessarily reflect the views of Brighton Park Capital. Nothing discussed today should be taken as investment advice or an offer or solicitation with respect to any securities. Any topics discussed today are for illustrative purposes only Listener Discretion: Please note the views and comments expressed by Logan on today's show is his own and do not reflect the views of ScaleView Partners. All topics covered in today's episode should not be taken as financial advice. Today's guest is Mark Dzialga, Founder and Managing Partner of Brighton Park Capital, a Greenwich-based growth equity firm that has scaled to nearly $4 billion in AUM since its founding in 2019. Brighton Park invests in entrepreneur-led, growth-stage software, healthcare, and tech-enabled services companies, with a portfolio that includes Darktrace, Coralogix, HITRUST, Canary Technologies, Orca AI, and Orbital Witness.Before founding BPC, Mark spent over 20 years at General Atlantic, where he chaired the Investment Committee from 2007 through 2017 and helped expand GA's footprint across Europe, Latin America, India, and Asia. He played a pivotal role in the growth and dominance of General Atlantic. Earlier in his career, Mark was co-head of the Technology M&A Group at Goldman Sachs.In today's conversation, we'll dive into why Mark left one of the most respected growth investing platforms in the world to build his own, how he's navigating the so-called "SaaS apocalypse" and the AI revolution, what revenue durability really means today, the question of will AI make new jobs, how to adapt and embrace AI in white collared jobs, how Brighton Park wins deals in a crowded growth equity landscape, and his advice for the next generation of investors trying to break into the industry.Support the show
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksKPV is the most underrated peptide out there. Almost nobody talks about it. In my opinion it should be one of the most demanded peptides we have. If I had to choose, I'd take it over BPC and TB-500 every single time.Here's why. KPV is a tiny three amino acid fragment of alpha-MSH. It directly blocks NF-kappa B, the master switch your body uses to turn inflammation on. Most peptides work around the edges. KPV shuts the alarm off at the door.In this one I cover all of it. What KPV is and how it works. Who actually benefits. Dosing by tier and by purpose. How to stack it with BPC, TB-500, LL-37, and your GLP-1. What to track on bloodwork. Cycling, sequencing, troubleshooting, and a full FAQ.If you've ever run a protocol that worked and then stalled out, this one is for you. Inflammation is almost always the rate-limiting step in healing.Make sure you're on the email list. And come join us in the Axion Collective for live coaching every Thursday.⚠️ For research and entertainment purposes only. ⚠️
Deb 00:00:01Imagine your body has a repair manual, instructions written in your cells that tell tissues how to heal, blood vessels, how to grow, and inflammation when to stop. But what if those instructions got lost somewhere along the way? Well, today I’m talking about peptides, tiny protein fragments that act like biological text messages. Two of them, BPC 157 and TB 500.They’re showing remarkable promise for gut repair, joint recovery, and tissue regeneration. But here’s what nobody’s telling you. Women respond differently to these healing signals, especially during hormonal transitions. And today, we’re uncovering the science behind these regenerative peptides, who actually needs them, and why your doctor might not know about them. Can you guys put our ad right in here and then I’ll go to the standard intro?Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective. And today we’re diving into regenerative peptides BPC157 and TB 500. If you or someone you love is struggling with slow recovery from injury, chronic joint pain, gut inflammation that just won’t quit, or you just feel like your body doesn’t bounce back the way it used to, this episode is for you. Grab a cup of coffee or tea or whatever helps you unwind, settle in, and let’s start you on your journey to deeper healing. We’ll do another sponsor break here. Deb 00:01:52So let’s start with the question I hear constantly in my practice. Dr. Deb, I’m doing everything right. I’m eating clean, I’m exercising, I’m taking my supplements, but I’m still not healing. What am I missing? Well, that answer might surprise you. Sometimes it’s not about what you’re putting in your body. It’s about whether your cells are actually receiving the repair signals they need. That’s where peptides come in. Think of peptides as The body’s original communication system. These short chains of amino acids are like biological post-it notes carrying instructions from one cell to another. They tell your human system when to calm down, your blood vessels when to grow and your tissues when to repair. Now here’s where it gets interesting for women specifically. We know that estrogen plays a massive role in collagen production, vascular health, inflammatory response. When estrogen starts declining, whether that’s perimenopause, postpartum, or even from chronic stress, our natural repair mechanisms slow down dramatically. You might notice it as my joints are aching more, I’m a little more fluid filled, you know, they hurt when I bend them, my injuries take twice as long to heal.Gut issues that suddenly appear out of nowhere and no matter what you do, they don’t seem to repair. Skin has lost its elasticity or just this general sense that your body isn’t keeping up anymore. This is where BPC 157 and TB 500 entered the picture. So BPC 157, short for body protection compound 157, is a naturally occurring peptide sequence found in your gastric juices. And according to a 2024 systemic review published in emerging use of BPC 157 in orthopedic sports medicine, this peptide promotes something called angiogenesis. That’s the formation of new blood vessels and they deliver oxygen and nutrients to damaged tissues. Now TB 500 is a synthetic fragment of thymus and beta-4. Deb 00:04:17A protein your body makes naturally during wound healing and research published in therapeutic peptides in orthopedics in 2025 shows that it works like a cellular first responder rushing to injury sites and coordinating tissue repair through a process called actin regulation. But here’s what makes these peptides different from just taking another supplement. They don’t force your body to do anything.They simply remind yourselves how to heal the way they used to. And for women navigating hormonal changes, autoimmune flares, chronic inflammatory conditions, that distinction matters enormously. all right, let’s get into some of these mechanisms because understanding how something works helps you make informed decisions about whether or not it’s right for you. So,Let’s look at the science. Do these peptides actually work? And if so, how do they work? Let’s start with BPC 157. This works through multiple pathways simultaneously. First, it activates growth factor receptors that stimulate fibroblasts. Those are the cells responsible for making collagen and rebuilding connective tissue. And according to research published in Frontiers and Pharmacology in 2023, titled Regeneration or Risk, BPC 157 also modulates nitric oxide signaling, which enhances vascular repair and reduces oxidative stress at the cellular level. So this is really important because many of us are nitric oxide deficient, especially as we get older, especially since the pandemic, we’re seeing a lot of people being more deficient in nitric oxide and you’re taking nitric oxide, many of you, to help with this process. But if we’re having other issues that don’t allow that nitric oxide to get where it needs to go, that could render it completely useless. So in plain English, when we’re talking about how BPC 157 helps the blood vessels work better and protects your mitochondria, big word for your energy factories and your cells from that inflammatory damage. Deb 00:06:38Now there’s studies in musculoskeletal and gastroenterology models that show BPC157 decreases inflammatory cytokines like TNF-alpha and IL-6. And these are chemical messengers that keep inflammation turned on. So by dialing them down, BPC157 creates an environment where healing can actually happen. Now, where do we know about this?TNFL and IL-6, well, we know it from viruses, we know it from Lyme disease, we know it from mold toxicity. These cytokines are turned up, they’re creating a massive inflammatory response in the body, and you’re struggling to get these things down because of that or potentially other reasons. So here’s where it gets really interesting with women in perimenopause or menopause. When estrogen declines, collagen synthesis slows down. And that’s why we see increased joint pain, slower wound healing, and our changes in the skin’s elasticity during this transition. We see the little wrinkles, the fine lines, we see the subcutaneous fat going away a little bit more. This is partially why this is occurring. And so from research shown in the Journal of Orthopedic Research in 2023 by Leibowitz and colleagues, that they suggest that BPC157 affects on the endothelial layers. So the cells lining the blood vessels and these may mimic some of the estrogen’s protective vascular effects without actually affecting your hormone levels. This is really huge because we know that as women lose estrogen, they have a higher risk for vascular events, heart attack, stroke, things like that. And if people have already had a heart attack or a stroke, We typically recommend that they don’t use estrogen because that could potentiate the risk for another heart attack or a stroke. But that means that you don’t gain the benefits of estrogen either. So if we think about this, we could potentially use BPC 157 to give us some of the benefits that we lost from having estrogen and potentially not being able to use estrogen. And that would be huge for us. Deb 00:08:57And not to mention the reduction of inflammation and the joint pain and the wound healing and the energy and the gut feelings. I mean, there’s just so many benefits to BPC 157 that we could talk about them all day long. But we’ve got to move on. So let’s talk about TB 500. Now this peptide works very differently. Its primary job is promoting cell migration, essentially telling repair cells to go to this spot and what to do when they get there. So it sends a signal, puts a little post-it stamp there and says, Hey, when you get there, fix A, B, C, and D. And there was a study in 2024 in cell biology international that demonstrated that TB 500 increases epithelial closure and improves tendon elasticity in models of repetitive strain injury. So let’s think about that a little bit. What does that really mean?That means faster recovery from exercise induced muscle damage, better healing of overuse injuries like tennis elbow or plantar fasciitis, improved scar tissue remodeling after surgery or a C-section, enhanced recovery from chronic inflammatory conditions affecting soft tissues. And I’ve talked about this several times. I have used these compounds post-surgical personally.And I remember going back to see my surgeon at the two to three week mark for follow-up. And she was amazed at how well everything was healing. And when I asked her if she wanted to know what I was doing, her response was no, but keep doing whatever you’re doing because it’s working. And after three weeks of a major pelvic repair surgery that I had, four hours in surgery, lots of sutures, not comfortable. I was actually walking a mile and didn’t have pain and I was recovering really well and felt amazing. And that is just not typically heard of in surgical procedures like mine. It’s usually a minimum of a six to eight week recovery before you’re starting to do that again. And I give all of the credit to these two peptides. Deb 00:11:17In my clinical practice, I see this play out constantly. Women who train hard, whether that’s CrossFit, running, yoga, or just trying to keep up with active kids, often hit a wall where their recovery can’t keep up pace with their activity level. And TB 500 helps to bridge that gap by optimizing the body’s natural repair timeline. But here’s what I want to emphasize with you. These peptides aren’t magic bullets.They work best when we combine them with proper nutrition and anti-inflammatory diet, adequate sleep, stress management, and we address the underlying root cause like the gut dysfunction or those hormonal imbalances. And they work much better when the hormones are balanced versus when they’re not. They’re amplifiers of your body’s existing healing capacity, not replacements for foundational health practices.So let’s have some real talk here. Let’s talk about evidence and what you need to know about that. Let’s take a drink, sorry. Now let’s address the elephant in the room. Regulatory status and safety. Neither BPC 157 or TB 500 are FDA approved for human medical use. They fall into a category called research compounds. And that means they’re legal to possess and use but they’re not approved as pharmaceutical drugs. And hopefully they will be back on our list of things to use relatively soon with the changes that Bobby Kennedy has made to peptides recently. So why does this matter? Because quality becomes a concern. Quality control is absolutely critical. You need to know where these compounds are manufactured, their source, their testing. their clarity, everything about them. There was a 2025 review in therapeutic peptides in orthopedics that concluded both peptides demonstrate strong regenerative signaling with minimal systemic side effects in preclinical studies. But, and this is really important, most of the robust data we have comes from animal models and cell culture models, not large scale human clinical trials. Deb 00:13:41Now that doesn’t mean that they don’t work. It just means that we are still in the early stages of understanding optimal dosing, treatment duration, and long-term effects in humans. So why do we have all of this great peptide information and we don’t quite have the ability to use them yet, or it’s extremely restricted?That comes under the guise of the FDA. came through the past administration with Biden where he removed a bunch of these peptides from the market. Both BPC and TB 500 were on the list of safe peptides to use before Biden made his changes. And it looks like they may be coming back relatively quickly for us here. So what we do have is growing clinical feedback from practitioners like myself. Who use these peptides in practice under careful supervision and under pilot studies on musculoskeletal recovery published in our organizations that we work with. So all of our information is documented and it is done under an observational study. There are other studies published in orthopedic and biomedical research from 2025.that actually found VPC-157 reduced pain scores by 35 % and improved functional mobility within eight weeks. This is really phenomenal because many people over the age of 40 are reaching for the Tylenol bottle, the Advil bottle, the Aleve bottle, which does a number on your kidneys and your gut and your liver. And it is really problematic to be using these things on a regular basis.And if we can use a compound that’s safe, that preserves the kidneys, the liver and the gut, why don’t we do that is the question that I have. Now, we see a lot of the same information in our clinic that we see in these studies. And it is the following things that we see. Significant reduction in joint pain and stiffness. I have a person that was looking at doing a knee replacement and we did 10 weeks of these two compounds. Deb 00:16:00And her knee pain reduced so much that she decided she didn’t feel like she needed that knee replacement right away, which is good because she is only 60 years old. And the length of that knee replacement wouldn’t be as long as it would if she could wait five or 10 years. The doctor didn’t say she needed to do it right away. She wasn’t that critical, but it was the pain that was driving her to the replacement. And so if we could preserve that and give her a reduction in pain, all the better to do that. We get faster recovery from surgical procedures, improved gut symptoms, especially in cases of leaky gut or inflammatory bowel conditions, better skin quality and wound healing, enhanced overall sense of resilience and recovery capacity. But here’s what you absolutely must know before considering peptide therapy. First, source matters. Because these aren’t FDA regulated pharmaceuticals, quality varies widely and you need to work with a physician who sources from compounding pharmacies 503A or 503B that provide certificates of analysis, third party testing and proper sterility verification. Secondly, context matters. Peptides work best as part of a comprehensive functional medicine approach. So if you’re still eating inflammatory foods, drinking alcohol, not managing your stress or your sleep, you have unaddressed gut dysfunction, and these peptides alone won’t fix those problems. Thirdly, realistic expectations matter. These aren’t overnight miracle cures. Most patients see gradual improvements over four to 12 weeks. Some respond dramatically, others see modest benefits. Individual variation is real. And fourth, medical supervision matters. Dosing, injection technique,monitoring for side effects and knowing when peptides are or are not appropriate. All of this requires clinical expertise. Now let me bust a few myths here because I hear this constantly. Myth number one, peptides are just for bodybuilders and athletes. That is false. While athletes use them for performance recovery, the therapeutic applications for chronic pain, gut healing and age related tissue decline are profound. Deb 00:18:26For everyday people. Myth number two, peptides will mess with my hormones. False. BPC-157 and TB-500 don’t interact with your endocrine system the way hormones do. They work through growth factors and cell signaling pathways. They are very different. Myth number three, if they’re not FDA approved, they must be dangerous. Not accurate.Many effective therapies exist in regulatory gray zones. What matters is quality sourcing, proper medical oversight, and informed consent. So the bottom line here is that these peptides show real promise backed by mechanistic science and growing clinical expertise, but they require responsible use, quality products, and realistic expectations. Now let’s talk about practical integration.Who should consider peptides? Well, so who actually benefits from the peptides? Let’s start there. Let me walk you through the three main categories I see. Number one is gut restoration. If you’re dealing with chronic gut inflammation, whether that’s IBS, inflammatory bowel disease, leaky gut, persistent digestive issues that haven’t responded to dietary changes alone, BPC 157 can be transformative.I had a patient recently, I’ll call her Sarah. She’s been struggling with severe gut pain and food sensitivities for three years. She tried elimination diets, probiotics, gut healing supplements, everything. And within six weeks of adding BPC 157 to her protocol, alongside the targeted nutritional therapy, her pain dropped by 70 % and she could tolerate foods that she hadn’t tolerated in years. Why does this happen? because BPC 157 directly supports mucosal integrity, the protective lining of your intestinal tract, and it reduces inflammatory cytokines and promotes healing of damaged tissue. Number two, muscle and joint recovery. This is where I see TB 500 shine. Women who are active, whether you’re a runner, a yogi, a cross-bitter, or someone who just wants to keep moving without pain. Deb 00:20:48They often hit a point where recovery becomes a very limiting factor. And maybe you’re dealing with chronic tendonitis, a nagging shoulder injury, a bad back that just will not quit, or just general achiness. It all makes you feel older and keeps you from being active the way you want to. TB 500 combined with therapies like red light therapy, PEMF, or targeted physical therapy, can dramatically accelerate soft tissue healing. I’ve seen recovery timelines cut in half for patients dealing with overuse injuries. Number three, menopausal transition support. This is where the intersection of peptides in women’s health gets really exciting. During perimenopause and menopause, declining estrogen affects collagen production, vascular health, and joint integrity, along with inflammatory processes and responses.Many women notice they just don’t heal as quickly and their joints hurt much more. Besides noticing their skin changes and their injuries linger longer. Low dose peptide protocols, often combining BPC157 for vascular and gut support with TB500 for soft tissue repair, can complement bioidentical hormone therapy or stand alone for women who can’t or don’t want to use hormones.Now I’m not saying that peptides replace your hormone optimization, but they can be powerful adjuncts that support tissue resilience during a time when your body’s natural repair mechanisms are shifting. Now, who should not use peptides? If you have any active cancer or a history of certain cancers, peptides that promote cell growth and angiogenesis might not be appropriate. If you’re pregnant or breastfeeding, we don’t have safety data.If you have severe kidney or liver disease, clearance and metabolism could be affected. You want to work with a practitioner who really understands this and be under medical supervision for these kinds of conditions. This really matters. A qualified functional medicine practitioner can assess your individual situation, run appropriate labs and determine whether peptides fit into your overall healing strategy. Remember, peptides are tools. They’re not magic. Deb 00:23:11They work best when you’re also addressing nutrition, sleep, stress, movement, and underlying root causes. They amplify your body’s healing capacity. They don’t replace the fundamentals. This is really important to understand. So thank you for joining me today on Let’s Talk Wellness Now. If this episode resonated with you, share it with another woman who’s ready to reclaim her body’s natural healing capacity. Remember, Wellness isn’t just about feeling good. It’s about thriving in every area of your life. Your body was designed to heal. You’re not a small version of a male. You are a woman with different biochemistry. And sometimes it just needs the right signals and the right support to remember how. If you’re ready to explore personalized regenerative medicine or peptide therapy as part of a comprehensive functional medicine approach,You can visit us at serenityhealthcarecenter.com. You can also follow us on Instagram, and you can look at my book, Seen at Last, and join the Seen at Last free community on Facebook, where we will provide all of this information and more for you. Until next time, I’m Dr. Deb, reminding you to take care of your body, mind, and spirit. Be well, and I’ll see you in the next episode.The post Episode 269 – Peptide Therapy for Women: How BPC-157 & TB-500 Heal Gut, Joints & Inflammation first appeared on Let's Talk Wellness Now.
From injury recovery to skin health to the growing longevity conversation, peptides are everywhere right now. But what are they actually, and does the science hold up? Dr. Sarah and Aalimah Sarah Ahmed unpack the evidence behind two of the most talked-about peptides, BPC-157 and GHC-Cu, so you can understand what's hype, what's real, and what might actually be worth your attention.Text to get in touch!Support the showIf you enjoyed this episode, subscribe and share! To help us continue this important work, become a sustainer at www.empowherhealth.org
Creadores: Emprendimiento | Negocios Digitales | Inversiones | Optimización Humana
En este episodio de Creadores Podcast, Marcelo Zegarra conversa con el Dr. Joaqui, anestesiólogo, especialista en dolor y experto en medicina regenerativa, para destapar toda la verdad detrás del boom viral de los péptidos para bajar de peso y la longevidad saludable.Finalmente, exploramos el futuro de la medicina de precisión, donde la inteligencia artificial promete diseñar péptidos a la medida exacta de cada paciente analizando cientos de biomarcadores como la insulina y la hemoglobina glicosilada.Shownotes00:00 | La verdad sobre los péptidos y la inteligencia artificial en medicina02:32 | Por qué se volvieron virales los péptidos para bajar de peso (El efecto Ozempic)04:16 | Qué es un péptido y cómo funciona la comunicación celular05:08 | Tipos de péptidos: Diferencias entre péptidos naturales y sintéticos06:51 | Por qué los péptidos no son suplementos alimenticios de venta libre17:33 | Cómo optimizar biomarcadores y salud con péptidos en la familia19:25 | Cómo mejorar la energía mitocondrial y el rendimiento sexual21:57 | La verdad sobre los péptidos metabólicos y la pérdida de grasa visceral25:05 | Los riesgos de perder masa muscular con péptidos para adelgazar27:36 | Qué hacer cuando usas péptidos: El plan obligatorio de ejercicio de fuerza29:42 | Cómo revertir la infertilidad y mejorar el microambiente celular32:41 | Por qué tienes la energía baja y cómo repararla desde la mitocondria40:39 | El protocolo médico de aplicación: Analíticas de sangre y resistencia a la insulina42:44 | Qué es la hemoglobina glicosilada y cómo mide la oxidación de tu cuerpo46:21 | Tipos de administración de péptidos: Vía subcutánea, oral, tópica y nasal49:55 | Cómo ciclar los péptidos de longevidad para evitar efectos secundarios52:51 | Los 5 errores y peligros graves de automedicarse con péptidos de internet55:16 | Por qué demandan a Ozempic: Casos de ceguera, tumores y cargas tóxicas59:36 | Cómo mitigar riesgos médicos empezando con dosis bajas1:02:58 | Cómo hacer un seguimiento con bioimpedancia, Dexa Scan y analíticas1:04:33 | Para qué sirve el BPC 157: El péptido para sanar lesiones, tendones e intestino1:10:30 | Contraindicaciones del BPC 157: Cuándo NO debes aplicártelo1:14:25 | Los beneficios del GHK-Cu (Tripéptido de Cobre) para la piel, cabello y células madre1:17:47 | La verdad sobre la Tesamorelina y la reducción de la grasa visceral1:22:09 | Qué es el Epitalón y cómo influye en los telómeros y la longevidad1:24:14 | Los mejores péptidos para el sueño profundo y la ansiedad (DSIP y Selank)1:29:28 | El futuro de la medicina de precisión: Péptidos personalizados con IA1:32:23 | Cómo llegar a los 120 años con vitalidad y envejecimiento saludable1:35:15 | El consejo final del Dr. Joaqui sobre el mercado negro de la saludSi te gustó este episodio, te recomendamos ver:- https://youtu.be/Bg0_zMYSdSM- https://youtu.be/MCkAu7OhAeY- https://youtu.be/1Lr90wz7fKY- Recibe 5% de descuento en tu suscripción de los mejores suplementos utilizando el código CREADORES en https://belevels.com/- Recibe acceso gratuito a mi lista de los 100 libros que transformarán tu vida aquí: https://www.creadores.co/newsletter- Únete a nuestra Escuela de Creadores, un programa de 12 semanas para transformar tu cuerpo, mente y negocios: https://creadores.co/escuela- Invierte en bienes raíces en EE. UU. con nosotros en Creadores Capital y genera retornos promedio del 20% anuales. Aplica aquí: https://www.creadorescapital.com/Redes de Dr. Joaqui:- https://www.instagram.com/dr.joaqui/- https://drjoaqui.com/- https://www.youtube.com/@cuerpomentemedicinafuncionaleiCreadores- Facebook: https://www.facebook.com/creadorespodcast- Instagram: https://www.instagram.com/creadorespodcast- Instagram: https://www.instagram.com/chelozegarra- TikTok: https://www.tiktok.com/@marcelozegarrac- Twitter: https://twitter.com/chelozegarrac- Email: https://www.creadores.co/contacto
Dr. Greg Jones discusses the "Wolverine Stack" protocol, which utilizes specialized peptides for healing and recovery. This includes a detailed look at BPC-157 and TB-500, highlighting how these peptides for injury repair work synergistically. Learn about this advanced peptide therapy to optimize healing and recovery from various physical challenges.The information provided in this video is solely for educational and informational purposes. It is not intended to provide medical advice or to diagnose, treat, cure, or manage any health condition. Viewing this content does not establish or imply a doctor–patient relationship. You should not rely on this content as a substitute for consultation with a licensed healthcare professional regarding your own specific medical questions or health concerns. Always seek the advice of your physician or other qualified healthcare provider before starting, stopping, or changing any medication, supplement, treatment, or lifestyle program. Never disregard professional medical advice or delay seeking it because of something you have seen in this video. If you believe you may be experiencing a medical emergency, call 911 or your local emergency number immediately.
What if the most talked-about healing peptide in biohacking came from your own stomach — and carried a risk nobody in the space is talking about?BPC-157, nicknamed "the Wolverine Peptide," has taken over fitness forums, longevity podcasts, and regenerative medicine circles. The preclinical data on tissue repair is remarkable. But the same biological mechanism that drives its healing power is the exact mechanism tumors use to survive and grow.BPC-157 is a synthetic 15 amino acid sequence isolated from human gastric juice, first identified in the early 1990s. It drives tissue repair through six mechanisms: angiogenesis via VEGF upregulation, nitric oxide pathway modulation, FAK paxillin signaling activation, growth hormone receptor upregulation in tendons and ligaments, anti-inflammatory cytokine downregulation, and free radical scavenging for cell protection. An active Phase II randomized controlled trial is currently evaluating BPC-157 for acute hamstring muscle strain repair. Its pro-angiogenic properties raise a theoretical cancer risk in individuals with undiagnosed early-stage tumors. WADA has banned it for competitive athletes. The FDA has reclassified its availability and the FDA Pharmacy Compounding Advisory Committee is reviewing its status on the approved bulk substances list.Dr. Joy Kong talks about:00:00 Meet The Wolverine Peptide02:40 Discovered Inside Human Gastric Juice03:42 Six Pathways That Drive Healing07:33 The First Real Human Trial07:58 Why The FDA Cracked Down09:24 The Hidden Cancer RiskAdditional Resources:✨ Visit My Clinic: Chara Health
Dr. Mike Hart interviews board-certified urologist Dr. Alex Tatum about peptide access, compounding, and men's health. Tatum argues many peptides are naturally occurring and lacked FDA commercialization incentives, says the FDA's 2023 move banning 19 compounds from Category 1 was contested due to no produced adverse-safety evidence, and describes the patient impact and advocacy around a July PCAC meeting. He explains most peptide APIs and many compounded GLP-1 ingredients come from China, while pharma-grade GLP-1s have more U.S. production. The discussion covers retatrutide's potential biologic classification (40–amino acid rule) and pricing implications, MOTS-c as an adjunct for low energy on GLP-1s, skepticism about cardarine, growth hormone secretagogues and cancer fears, TRT dosing frequency, sleep apnea screening, HCG's roles, and penis enhancement via traction for length and hyaluronic acid filler for girth, emphasizing expectations and mental health. Dr. Alex Tatem is a board-certified urologist focused on men's health, hormone optimization, male fertility, and sexual wellness. In this episode, he joins Dr. Mike Hart to discuss the changing landscape of peptide therapy, including FDA restrictions, compounding pharmacies, drug supply chains, and the growing debate around access to treatments such as BPC-157, MOTS-c, and retatrutide. He also breaks down practical considerations for men using testosterone replacement therapy, including HCG, fertility preservation, dosing frequency, estrogen-related side effects, and sleep apnea risk. Drawing from his experience treating a wide range of patients, he shares a harm-reduction approach to performance medicine and explains what men should understand before considering growth hormone peptides, GLP-1 medications, or penile enhancement procedures. Dr. Alex Tatem Website https://dralextatem.com/ Dr. Alex Tatem Instagram https://www.instagram.com/dralextatem/ Huberman Lab — Peptides: The Science, Uses & Safety | Dr. Abud Bakri https://www.hubermanlab.com/episode/peptides-the-science-uses-and-safety-abud-bakri FDA Pharmacy Compounding Advisory Committee Meeting — July 23–24, 2026 https://www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026 FDA Bulk Drug Substances Under Section 503A https://www.fda.gov/drugs/human-drug-compounding/bulk-drug-substances-used-compounding-under-section-503a-fdc-act FDA Compounding Safety Risks https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks Semaglutide / Ozempic https://medlineplus.gov/druginfo/meds/a618008.html Tirzepatide / Mounjaro https://medlineplus.gov/druginfo/meds/a622044.html Retatrutide Clinical Trial https://clinicaltrials.gov/study/NCT05929066 Testosterone Cypionate https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=testosterone%20cypionate Human Chorionic Gonadotropin / HCG https://pubmed.ncbi.nlm.nih.gov/?term=human+chorionic+gonadotropin BPC-157 https://pubmed.ncbi.nlm.nih.gov/?term=BPC-157 KPV Peptide https://pubmed.ncbi.nlm.nih.gov/?term=KPV+peptide TB-500 / Thymosin Beta-4 https://pubmed.ncbi.nlm.nih.gov/?term=thymosin+beta-4 MOTS-c https://pubmed.ncbi.nlm.nih.gov/?term=MOTS-c CJC-1295 https://pubmed.ncbi.nlm.nih.gov/?term=CJC-1295 Ibutamoren / MK-677 https://pubmed.ncbi.nlm.nih.gov/?term=ibutamoren+MK-677 Cardarine / GW501516 https://pubmed.ncbi.nlm.nih.gov/?term=GW501516+cardarine PhalloFILL at Urology of Indiana https://menshealthin.com/services/phallofill/ Hyaluronic Acid Penile Girth Enhancement Overview https://auanews.net/issues/articles/2024/august-extra-2024/office-and-surgical-technologies-the-evolving-landscape-of-penile-girth-enhancement Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:33 Are Peptides Threatening Pharma 01:17 Patent Law and FDA Categories 02:19 The 2023 Peptide Ban Fallout 03:59 Safety or Money Debate 06:09 China Supply Chain Exposed 11:33 RFK Jr Peptide Messaging 16:01 Retatrutide Biologic Fight 20:51 What Biologic Status Costs 25:27 MOTS-c as GLP-1 Booster 28:43 Growth Hormone Cancer Myth 32:18 Sleep Effects and Bryan Johnson 35:04 Microplastics and Saunas 36:48 Cardarine Cancer Risk 40:07 TRT and HCG Basics 45:08 HCG Dosing Nuance 49:06 Daily TRT Microdosing 52:03 Sleep Apnea on TRT 56:34 Penis Enhancement Options 01:02:54 Realistic Expectations 01:04:46 Wrap Up and Where to Follow The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
BPC-157 is derived from a protein found in the human stomach. It promotes healing in a variety of health conditions, from muscle and tendon injuries to gut health and brain fog. BPC-157 is available as an oral pill or an injection into the fatty tissue (subcutaneous injection) . In this podcast, we'll discuss the differences between these two dosage forms and which may be better for you. Read the Full Episode Transcript: https://pepties.com/bpc-157-injectable-vs-oral/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order: https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/
Peptides have exploded in popularity over the last few years, but separating legitimate science from marketing hype has become increasingly difficult. In this episode, Dr. Kyle Gillett joins Doug Larson, Dr. Mike Lane, and Coach Travis Mash for a deep dive into the world of peptides, growth hormone secretagogues, GLP-1 medications, and emerging therapies that may shape the future of performance, recovery, body composition, and longevity. They unpack what peptides actually are, which compounds have meaningful clinical research behind them, and where caution is still warranted, especially when it comes to growth factors, angiogenesis, and potential cancer-related concerns. The conversation covers BPC-157, TB-500, Tesamorelin, Retatrutide, Selank, PT-141, myostatin inhibitors, mitochondrial peptides, and the next generation of obesity and metabolic health drugs. Along the way, the group explores practical questions athletes and health-conscious individuals are asking every day: Can peptides help recovery? Are there compounds that improve cognition or libido? What are the tradeoffs of GLP-1 medications? And how close are we to drugs that can meaningfully increase muscle mass the way GLP-1s improve fat loss? Whether you're curious about performance enhancement, injury recovery, healthy aging, or simply trying to understand what all the peptide buzz is about, this episode provides a balanced, practical look at one of the fastest-moving areas in modern health and performance. Links: Doug Larson on InstagramCoach Travis Mash on Instagram
Your body already makes peptides every single day — so before you write them off as another wellness trend or jump on the Ozempic hype train, it's time to actually understand what they are. In this episode of The Wellness Effect, we breaks down peptides from the ground up — no hype, no fear, just a real explanation of what they are, how they communicate with your body, and why the conversation is so much bigger than weight loss. She walks through five specific peptides (semaglutide/Ozempic, retatrutide, BPC-157, GHK-Cu, and CJC-1295/ipamorelin), explains where they sit on the spectrum between supplements and steroids, and makes the case for why foundations always come first — even if you're curious about peptides for gut healing, skin, recovery, or longevity. KEY TAKEAWAYS: 1. Peptides aren't supplements and they aren't steroids — they're precision keys that fit one specific lock and turn on one specific system. More targeted than a supplement, way less system-wide than a steroid. 2. "Peptides" ≠ "Ozempic." The peptide world covers gut healing, skin, recovery, longevity, and more. The weight-loss lens is exactly why everyone's either over-hyped or scared. 3. Foundations first — always. Sleep, food, movement, stress. No peptide, no matter how well-targeted, will land in a body running on empty. Chapters: (00:00) Welcome (00:51) What Even Is a Peptide? The Lego Brick Breakdown (05:45) Peptides as Messengers: The Lock and Key System (06:50) How Peptides Differ from Hormones (10:54) Peptide Levels Decline with Age (and Why That Matters) (12:44) The Spectrum: Supplements → Peptides → Steroids (19:24) Peptides vs. Endocrine Disruptors — Are They the Same? (25:20) Why Is Everyone Suddenly Talking About Peptides? (31:10) Peptide #1: Semaglutide (Ozempic/Wegovy) (39:45) Peptide #2: Retatrutide — The Next Generation GLP-1 (42:52) Peptide #3: BPC-157 — Gut Healing & Injury Recovery (47:17) Peptide #4: GHK-Cu — The Skin, Collagen & Longevity Peptide (53:47) Peptide #5: CJC-1295 + Ipamorelin — Growth Hormone & Recovery (01:01:00) Why Foundations Always Come First (01:09:57) The Wrap-Up: What to Actually Take Away From This Want to Work With Us? Join us in the Root Cause Reset Program: https://www.lifestyleucoaching.ca/wellness-effect-906145 and use code "Wellness Effect" for a FREE functional lab test when you join the program. Follow us on Instagram: The Podcast: https://www.instagram.com/thewellnesseffectpod/ Lacey Iskra - https://www.instagram.com/laceeiskk/ Jensen - https://www.instagram.com/wellnesswjensen/ Kira Iskra - https://www.instagram.com/wellbykira/ Lifestyle U have helped over 1,000+ women transform their mind and body and become the best version of themselves. Want to be next? Click Here to Apply! - https://www.lifestyleucoaching.ca/apply If you loved this episode and want to hear more, subscribe and leave a review! Share this episode with a friend who's ready to start their own wellness journey. Follow us on Instagram at https://www.instagram.com/thewellnesseffectpod/ to stay up-to-date with the latest episodes and tips.
From injury recovery to skin health to the growing longevity conversation, peptides are everywhere right now. But what are they actually, and does the science hold up? Dr. Sarah and Aalimah Sarah Ahmed unpack the evidence behind two of the most talked-about peptides, BPC-157 and GHC-Cu, so you can understand what's hype, what's real, and what might actually be worth your attention.Text to get in touch!Support the showIf you enjoyed this episode, subscribe and share! To help us continue this important work, become a sustainer at www.empowherhealth.org
In this episode of The Better Life, Dr. Pinkston sits down with Ray Solano, pharmacist and founder of PD Labs, to expose the massive barrier to entry in the traditional pharmaceutical industry and explore why highly effective treatments often get buried by "Big Pharma." If a medication can't guarantee a billion-dollar market, major pharmaceutical companies won't touch it—even if it could save or drastically improve lives. Dr. Pinkston and Ray break down how the current clinical trial system is flawed, the massive price discrepancies between commercial biologics and tailored solutions, and why looking at global case studies and cellular science is more reliable than the corporate "show me the science" narrative. Key Topics Covered in This Episode: The Billion-Dollar Drug Hurdle: Why life-changing formulas for conditions like Peyronie’s disease and localized inflammation are ignored by major drug companies. The $22,000 Contrast: Dr. Pinkston shares a shocking look at the monthly cost of commercial autoimmune biologics versus affordable, root-cause healing. The Power of Transdermal Peptides: How PD Labs successfully formulated BPC-157 as a topical application to provide instant relief for tendonitis and muscle inflammation. Demystifying Generics & Compounding: The hidden truth about bioequivalence versus therapeutic equivalence in generic medications. Alternative Therapies That Work: Insights into the neurological benefits of Leucovorin, using Ivermectin in combination oncology therapies, and the anti-aging benefits of topical Glutathione and GHK Copper for summer skincare. The Telemedicine Trend: A warning on the safety risks of modern online prescription platforms that over-medicate without standard clinical overviews. Visit PD Labs: pdlabsrx.com Call PD Labs Pharmacy: 888-909-0110 (For clinical overviews, nutritional workups, and custom compounding programs) Watch More Episodes: Find all previous shows from the last four years at drpbetterlife.com See omnystudio.com/listener for privacy information.
Andrew Huberman Biography Flash a weekly Biography. Andrew Huberman has had a relatively quiet but still telling few days, the kind of stretch that says more about long‑term trajectory than splashy headlines. No major scandals, no viral Twitter wars, but a steady consolidation of his position as a public scientist who is inching closer to becoming an all‑purpose health and performance brand. The most concrete new content is around peptides. On YouTube, the Huberman Lab channel released or amplified a long-form discussion with physician Abud Bakri on the peptide BPC‑157, where Huberman walks listeners through its Croatian origins, animal data on tendon and nerve repair, and the safety controversies around angiogenesis and growth factor signaling, while repeatedly stressing that the data are largely from animal models and that human safety is not established, according to the YouTube conversation with Dr. Bakri. In a companion discussion on Pinealon, he highlights early data suggesting possible improvements in REM sleep and cognition but again frames it as emerging, not settled, science, as shown in that same Bakri collaboration on YouTube. These peptide episodes are biographically significant: they push Huberman further into the contested space where cutting‑edge performance science brushes up against unapproved therapeutics, a place that both fuels his influence and invites scrutiny. In parallel, the Huberman Lab Essentials feed continues to roll out short, highly produced clips distilling protocols on topics such as psychedelics and neurostimulation for brain health, per the Huberman Lab Essentials page. This Essentials packaging signals an ongoing shift from pure podcasting into a layered media product: long episodes for deep‑dive fans, short protocol hits for the habit‑stacking masses. There have been no widely reported major public appearances or new academic appointments in the last few days in mainstream outlets, and no front‑page headlines featuring his name on major news sites. Social media chatter continues at a low hum: fitness creators, biohackers, and endurance athletes keep clipping older Huberman quotes on managing race‑day anxiety, caffeine timing, and circadian habits, but that is recirculation, not new narrative. Any talk of upcoming book deals, new supplement company stakes, or TV projects circulating on fan forums at the moment remains speculation and is not confirmed by primary reporting from major publishers or by Huberman himself. In short, these last days are about consolidation: more peptide discourse, more protocol packaging, and a still‑growing archive that future biographers will mine to chart how a Stanford neuroscientist became a global behavior‑change franchise. Thanks for listening and be sure to subscribe so you never miss an update on Andrew Huberman, and search the term Biography Flash for more great biographies. Thanks for listening. This has been a Quiet Please production. Get the best deals https://amzn.to/3ODvOta
In this Q&A episode of the Her Stack Series, I'm answering the peptide questions you're asking me every single day in my DMs and comments: → Can I take peptides while breastfeeding? → What if I have a personal or family history of cancer? → Why won't my postpartum belly fat budge, even when I'm doing everything "right"? → Blends vs. single peptides, which is right for me? → How do I build my own peptide stack without ending up on eight injections a day? I'm unfiltered in this one. I share why there will never be clinical trials on peptides during breastfeeding (and what that really means for you when you're making the decision), the truth about growth hormone, IGF-1, and theoretical cancer risk, and my honest take on why most peptide advice from men completely misses the mark for women. Join The Mother's Protocol Program for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT: 00:00 — Welcome + episode intro 00:53 — Doors close Sunday: The Mother's Protocol Program 06:51 — A personal moment: new beginnings 09:07 — Q1: Can I take peptides while breastfeeding? 20:48 — Q2: Do peptides cause cancer? (BPC-157, growth hormone, IGF-1) 26:16 — Q3: Stubborn postpartum weight (MOTS-c, AOD 9604) 30:39 — Q4: Blends vs. single peptides (Glow, Wolverine, CJC/Ipamorelin) 33:46 — Q5: How to build your own peptide stack 39:14 — Wrap-up RESOURCES: — The Mother's Protocol Program: my 12-week group program for women + mothers. Doors close Sunday, we start Monday June 8. — Her Stack Planner: my peptide planner for women. Digital available now, physical coming this summer. — Free Peptide Masterclass replay — available until Sunday. CONNECT: Instagram: @biohackingbrittany Website: biohackingbrittany.com Next week on the Her Stack Series I'm going deep on body composition — every peptide for weight loss, the nutrition + exercise foundation, and what actually works postpartum, perimenopause, and menopause.
Timestamps : 00:00 — Introduction & Meet the Holistic Kids 01:31 — Introducing Dylan Gemelli: Wellness Revolutionary 03:13 — Dylan's Backstory: From Athlete to Prison to Purpose 07:19 — What Are Peptides? A Beginner's Breakdown 09:44 — Types of Peptides: Healing, Growth & Weight Loss 15:19 — Mind & Body for Kids: Dealing with Pressure & Bullying 20:13 — What Does "Being Healthy" Really Mean? 24:08 — How to Start: Building a Healthy Daily Routine 31:52 — Key Takeaways & Episode Recap In this inspiring episode of The Holistic Kids Show, hosts Zane, Adeelah, and Emad sit down with Dylan Gemelli — wellness revolutionary, biohacker, and host of the top-ranked Dylan Gemelli Podcast — for a conversation that's as real as it gets. Dylan opens up about his remarkable journey: from college athlete to prison, and then to rebuilding his life at 30 through the power of health, faith, and relentless self-education. He breaks down what it truly means to be healthy — and it goes far beyond the gym. In this episode, you'll learn: What peptides are and how they can support healing, muscle, gut health, and anti-aging (with beginner-friendly breakdowns of BPC-157, KPV, GHK-Cu, and more) Why spirit, mind, and body must all be in alignment for real health How kids and teens can protect their mental health in a world dominated by social media and screens The simple daily routine Dylan swears by — morning sunlight, gratitude, movement, and prayer Why weight loss shortcuts often do more harm than good How to stop caring about what others think — and why that's one of the most powerful health habits you can build Dylan's message is clear: health is a work in progress, humility is your superpower, and every hardship is just training for something greater. Key Takeaways: You are only as good as what you know today — stay humble and keep learning No one person is better than another; we all have something to offer Real health means spirit + mind + body working together Build a daily routine: gratitude, sunlight, movement, and quality sleep Forgive, release, and trust — your mental and spiritual health depend on it About Dylan Gemelli: Dylan Gemelli is a prominent figure in the fitness and biohacking world, known for his expertise in nutrition, cellular health, neuroscience, and anti-aging. His podcast consistently ranks #1 in Health & Fitness and top 20 overall on Apple Podcasts. Find him at dylangemelli.com or @dylangemelli on Instagram and YouTube. The Holistic Kids Show — where kids empower kids. Subscribe, leave a review, and help us build a healthier future for the next generation. Disclaimer: This podcast is for informational purposes only and does not constitute medical advice. --- Learn more about Dr. Madiha Saeed at https://holisticmommd.com, or follow her on social media @HolisticMomMD
Links, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTB-500 spends way too much time in BPC-157's shadow. I wanted to fix that.This is my full TB-500 masterclass. I go deep on what this peptide actually does, and why it works so differently than BPC even though we lump them together as the Wolverine stack.First I clear up the confusion between TB-500 and thymosin beta-4, because most people have no idea what they're actually buying. Then I break down the mechanism in plain language. Think of TB-500 as the foreman on a job site, moving the right materials to the right injury at the right time.I cover who it's for, who should skip it, and my full dosing tiers from general recovery up to severe injury. We get into cycling, reconstitution, injection technique, and how to stack it with BPC, GHK, and the growth hormone peptides.I also answer the big questions. Is it legal? Will it cause cancer? Will it touch your hormones? Does it grow hair?If you want more from me, get on the email list and check out the Axion Collective. Both links are in my bio.Enjoy this one. I love TB-500.
Peptides are huge right now. Influencers are telling us they can work wonders for all sorts of stuff. Struggling with an annoying injury that won't heal?? Belly fat that's pissing you off? Low energy? Gut issues?? There's a peptide out there for you. People are buying peptides off the internet and injecting themselves with them, saying it's life changing. But away from the internet hype, there is actually a potential revolution happening in medicine around peptides. So we're finding out what scientists are excited about here, and we look deeply at the science behind two massive peptides: BPC-157 and MOTS-c. And we'll also look at the risks: Could peptides give you cancer? On this episode we talk to Dr. Hassy Cohen, Dr. Keith Baar, Dr. Dhruv Khullar and Dr. Cory Mayfield to get to the bottom of this. Find us on Youtube! We're at https://www.youtube.com/@ScienceVsPodcast Find our transcript here:https://tinyurl.com/ScienceVsPeptides In this episode, we cover: (00:00) Peptides are everywhere right now (03:56 ) What are peptides? (04:39 ) The peptide revolution in medicine (09:56) MOTS-c: Should you take it? (15:56 ) BPC-157: Can it heal you? (26:33) What are the risks? This episode was produced by Wendy Zukerman, with help from, Rose Rimler, Ekedi Fausther-Keeys, Meryl Horn and Michelle Dang. We're edited by Blythe Terrell. Fact checking by Diane Kelly. Video editing and sound mix by Bobby Lord. Music written by Bumi Hidaka, Peter Leonard, Emma Munger and Bobby Lord. Thanks to the researchers we spoke to for this episode including Dr. Dana Lis, Dr. Pouya Faridi and Dr. Timothy Piatkowski, as well as the Australian Science Media Centre. A big thanks to Joseph Lavelle Wilson and the Zukerman family. Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In this Ask Me Anything episode, Dr. Will Cole and his team answer three listener questions that go deeper than most: BPC-157 for osteopenia at 35 and the full food-first bone density protocol, what to do when you live within a mile of a golf course and have Hashimoto's while pregnant, and ovarian cysts with a doctor who only offers birth control. They also cover the PCOS-to-PMOS name change — what it means clinically, why functional medicine has known about the metabolic component for years, and whether the timing of the rebrand is a little too convenient given the GLP-1 explosion. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Head to http://bioptimizers.com/willcole and use my exclusive code WILLCOLE to get 15% off any order!Sign up for your one-dollar-per-month trial and start selling today at SHOPIFY.COM/WILLCOLE!Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/artofbeingwell. Find your favorite flavor, or share with a friend.Head to MANUKORA.com/WILLCOLE to save up to 31% plus $25 worth of free gift swith the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook.Go to lyma.life and use code WILL10 for 10% off the LYMA Laser. Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
En este episodio de Café en Mano Podcast, vuelve el Dr. Paco para hablar de temas que cada vez más gente busca en internet, pero no siempre entiende bien: inteligencia artificial en medicina, dopamina, redes sociales, burnout médico, péptidos, proteína, salud mental y cómo todo esto afecta tu cuerpo y tu corazón.Hablamos de cómo el AI y Google están cambiando la forma en que los pacientes buscan información médica, por qué tanta gente llega al internet pensando que se va a morir, y cuál es el rol real de la inteligencia artificial dentro de la medicina. También tocamos el tema de la dopamina artificial, el efecto del celular, las redes sociales, el sedentarismo y cómo todo eso impacta nuestro bienestar físico y emocional.Además, entramos en uno de los temas más comentados ahora mismo en fitness y wellness: los péptidos, los GLP-1, el mercado negro, los riesgos de usar sustancias no estudiadas correctamente y por qué no todo lo que ves online es seguro. También hablamos del burnout en los médicos, la salud mental en Puerto Rico y por qué los doctores también necesitan hablar, pedir ayuda y cuidarse.Gracias a Fuse Telecom, internet sin preocupaciones.Y gracias a Café Dos Caminos. Entra a cafedoscaminos.com y usa el código CAFÉENMANO para 10% de descuento.Suscríbete, comenta y comparte.#CafeEnMano #DrPaco #Salud #InteligenciaArtificial #Peptidos #Burnout #Dopamina #PuertoRico00:00 Intro + Café Dos Caminos + Fuse Telecom01:20 El AI en medicina y cómo ya está cambiando la práctica médica04:30 Google, internet y pacientes que llegan pensando lo peor08:50 Cómo los médicos usan AI como herramienta, no como diagnóstico final10:30 El marketing de la proteína y los productos ultraprocesados14:36 Dopamina artificial vs dopamina real18:00 Celular, redes sociales y cómo afectan tu bienestar21:13 La salud mental del médico en Puerto Rico25:30 Competencia, burnout y la presión desde escuela de medicina29:00 Por qué los médicos también necesitan ayuda33:02 Qué tan real es The Pitt y cómo se compara con la vida médica real39:30 Preworkouts, creatina y el hate en redes44:04 Qué son los péptidos y por qué están tan de moda49:47 Wolverine Stack, BPC-157 y el mercado negro de péptidos55:16 Riesgos, estudios y por qué no todo lo online es seguro58:30 Conocimiento como flex y por qué hay que educarse mejor01:00:30 Cierre + cómo enviarle preguntas al Dr. Paco
What if the peptide your favorite influencer is swearing by has never once been tested in a human clinical trial?Michelle MacDonald sits down with drug development scientist Leigh Baxt, PhD for a conversation that cuts straight through the wellness peptide industry.Together they break down how drugs actually make it from an idea to FDA approval, why 99% of them never do, and what it means that the peptides flooding your social media feed are, in most cases, sitting at the very earliest stage of that process with almost no human data behind them. This episode digs deep into BPC-157 specifically, examining why the science raises serious red flags, and what informed consent actually sounds like when a clinician is promoting something with this little evidence. This information is essential listening for women who want to take charge of their health, cut through the marketing noise and make truly informed decisions.Favorite Moments1:57 The Staggering Failure Rates Behind Every Drug You've Ever Taken3:07 From Idea to FDA Approval: What the Process Actually Looks Like5:28 BPC-157: Why the Red Flags Are Hard to Ignore12:49 Stacking Peptides & the Drug Interaction Problem Nobody Talks About16:30 When Clinicians Become Marketers22:21 How to Use ClinicalTrials.gov to Check the Evidence Yourself28:22 The Patent Myth That Peptide Promoters Keep Repeating"I want people to be informed. I want them to understand what data does and doesn't exist. Most importantly, I want them to be able to differentiate data from marketing — because even the most seasoned scientists can get sucked in." — Leigh Baxt, PhDGUEST: LEIGH BAXT, PhD - DRUG DEVELOPMENT SCIENTISTInstagram | LinkedInLeigh works in early-stage preclinical drug development, the phase where 90% of ideas fail before they ever reach a human. Her work focuses on understanding whether promising biological mechanisms can actually be turned into safe, effective therapeutics. She volunteers her expertise with the Unbiased Science team to help the public understand how medicines are made, why the vetting process matters, and how to tell the difference between data and marketing.CONNECT WITH MICHELLEWebsite | Instagram | YouTube | Facebook | XAbout Michelle:Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.Where to Watch/Listen:Website Apple Podcasts Spotify YouTubeLeave a rating for this podcast with one click.Nothing in this video or podcast constitutes medical advice. Always consult a qualified healthcare professional before making changes to your health or fitness routine.
Needle-Free Peptides, US Manufacturing, BPC-157, Thymosin Alpha-1, GLP-1s, Microneedle Patches, and How to Avoid Contaminated Peptides Peptides are one of the most powerful tools in biohacking and anti-aging medicine, and until now, most people couldn't access them safely, legally, or without a needle. This episode changes that. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days Host Dave Asprey sits down with Justin Kirkland, a longevity medicine expert with over 30 years in drug development and pharmaceutical innovation. Kirkland holds multiple drug synthesis and formulation patents, has founded multiple pharmaceutical companies, and is one of the few people in the world manufacturing peptides entirely on US soil, controlling every step of the synthesis process from raw amino acids to finished product. If you want to understand what is really inside your peptides and why it matters for your longevity and human performance, he is the person to listen to. Dave and Justin go deep on why most peptides on the gray market contain dangerous residual compounds that can spike liver enzymes and cause real harm, why Chinese-sourced APIs are not always what they claim to be, and how a new generation of needle-free delivery systems including microneedle patches and auto-injectors is making peptide therapy accessible to anyone serious about longevity and human performance. They also cover how AI and functional medicine are converging to make peptide protocols personalized based on genetics and microbiome status, why the thymus gland is one of the most overlooked anti-aging targets in the body, and what the suppression of peptide research reveals about who really controls your access to health tools. You Will Learn: Why many gray market peptides contain toxic residual acids that damage the liver and how to identify clean products How microneedle patches and auto-injectors are replacing traditional injections for peptide delivery Which peptides are most effective for longevity, immune system repair, and human performance including BPC-157, Thymosin Alpha-1, and growth hormone secretagogues Why your genetics and gut microbiome determine whether a peptide will work for you at all How the thymus gland controls your immune system and why it disappears by your mid-20s What the suppression of peptide research tells you about Big Pharma's control over your supplement and nootropics access Why US-manufactured peptides represent a new standard for safety and quality in biohacking How AI is transforming personalized peptide protocols in functional medicine Which peptides are overhyped and which ones actually move the needle on anti-aging and recovery How to store, mix, and dose peptides correctly to avoid the mistakes most people using them are making right now Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Fatty15 is on a mission to support Healthy Aging for All, including all ages and stages of life. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout. - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Justin Kirkland, peptides, needle-free peptides, microneedle patch, BPC-157, Thymosin Alpha-1, ipamorelin, CJC-1295, PT-141, KPV peptide, Dihexa, growth hormone secretagogue, peptide purity, TFA contamination, gray market peptides, US manufactured peptides, oral peptides, transdermal delivery, thymus gland, anti-aging, biohacking, longevity, functional medicine, peptide auto-injector, compounding pharmacy Resources: • Go to Aminoinnovations.com and use “asprey20” for a discount through the next 7 days • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro & Guest Welcome 01:55 – Censorship & Platform Bans 06:20 – Peptide Science & Bioavailability 07:20 – Delivery Methods 14:30 – Supply Chain & US Manufacturing 17:01 – Manufacturing Risks & Contamination 24:43 – Peptide Stacks 28:41 – Immune Peptides & Thymus 30:57 – Overhyped Peptides 41:00 – Alternative Delivery (Patches, Nasal, Rectal) 47:25 – Side Effects & Risk 50:30 – Mixing & Storage Tips 54:05 – Wrap-Up & Where to Buy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dr. Abud Bakri, MD, is a board-certified internal medicine physician and expert in the science and clinical use of peptides. We discuss the history, uses, sourcing and safety of BPC-157, GHK-Cu, pinealon, epithalon, GLP-1s, retatrutide, melanotan and growth hormone-promoting peptides. We discuss the gap that exists between animal and human data and meaningful differences in the sources for different peptides. For those interested in peptides, Dr. Bakri provides a grounded look at the science, risks and uncertainties shaping the field today. Read the show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Abud Bakri (00:03:33) What are Peptides?, Receptors (00:06:26) BPC-157, Discovery, Animal Proteins (00:11:19) BPC-157, Animal Data, Regeneration (00:12:27) Sponsors: Eight Sleep & Lingo (00:14:51) BPC-157, Regeneration & Healing, Neurological Effects (00:19:27) Adverse Events, Clinical Trials & Legality of BPC-157 (00:29:41) GLPs & Compounding Pharmacy; Peptides & Gray Market (00:35:25) Manufacturing, Compounding Pharmacies, Gray Market, Black Market (00:41:32) Peptides & Tumor Growth?; Angiogenesis (00:45:17) Sponsor: AG1 (00:47:01) Pharmaceutical Patents, Clinical Trials for BPC-157, Potential Outcomes (00:54:19) BPC-157 Healing, Patient Experiences (01:01:22) Physician Counsel, FDA Legality, Malpractice (01:07:25) Pinealon, Epithalon, Discovery; Sleep & Cognitive Performance, Risks (01:18:17) Sponsor: Function (01:19:55) Pineal Age Deterioration, Epithalon, Eye Health (01:29:38) Thymus, Age Shrinkage; Thymosin Alpha-1, Immune Function (01:38:13) TB-500; Pet Health; Thymic Peptide Doses, Thymulin, Zinc (01:49:13) Sponsor: LMNT (01:50:33) GHK-Cu (Copper GHK), Collagen (01:55:32) Illness Recovery, Thymic Score, Tool: Blood Test & Immune Cell Counts (02:04:01) Growth Hormone Secretagogues, Age Decline, Cancer Risk, Insulin (02:15:36) GHK-Cu, Topical Cream, Red Light Therapy (02:20:25) GLPs, Discovery, Physical & Cognitive Long-Term Effects, Fertility (02:33:53) Retatrutide; Drug Patents & Nomenclature (02:39:03) Peptides: Women Reproductive Disorders; TBI, Neurologic Effect; Safe Sources (02:45:34) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
Peptides are everywhere right now, and the people who tried to keep them out of your hands ran the last FDA. Dr. Chris Shade, founder of Quicksilver Scientific, sits down to explain what peptides actually are and why so many people are suddenly paying attention. He argues the problem with most supplements is simple: you swallow the capsules and feel nothing because the compounds never reach your blood. His company's fix is a liposome and nanoemulsion delivery system he calls the "biochemical syringe," which he says pushes peptides through the mouth and gut straight into circulation, no needles required. Then it gets political. Shade points out that the previous administration's FDA, staffed by people who came out of the pharmaceutical industry, pushed peptides onto the do-not-compound list while those same companies sold GLP-1 drugs that are themselves peptides. He credits HHS Secretary Robert F. Kennedy Jr. and the MAHA movement with reversing that restriction and reopening access. If you've been curious about oral peptides, bioavailability, copper GHK, BPC-157, NAD precursors, glutathione, or how detox binders and liposomal supplements fit into a daily routine, this is where to start. Shade also lays out how long he thinks someone should commit to a protocol before judging whether it works. 0:00 Quicksilver Scientific and the supplement problem0:08 Why most supplements never get absorbed1:14 Oral peptides and the "biochemical syringe"1:58 GLP-1s are peptides too2:18 Where to start: copper GHK and BPC-1574:02 RFK Jr., MAHA, and the FDA peptide ban6:03 Binders and detoxification7:48 What Shade actually takes9:16 How long to commit and how to measure results
In this episode the guys break down the best exercises and strategies for getting a crazy pump — hydration with sodium, carb timing, full range of motion, optimal rep ranges, superset strategies, and flexing between sets. Then they coach live callers submitted through mplivecaller.com — Lindsay from Alberta on reverse dieting and building glutes on too few calories, Alex from Florida on weekend tracking inconsistency and a military fitness test, Brianna from North Carolina on chronic overtraining and learning to let go, and Avery from Michigan on fat intake while cutting and dialing in nutrition before her July wedding. MAPS 15 BOGO — https://maps15bogo.com Buy 1 get 1 FREE — limited time (all 7 MAPS 15 programs same price) SPONSORS Vita Bella / MP Hormones — https://mphormones.com Code: MINDPUMP365 — Free 10-min consultation + raffle entry Free consultation booking: https://calendly.com/vb-consultations/complimentary-consults?month=2026-05 Raffle: 3 free memberships + 10 free essential labs given away this month Dose for Your Liver — https://dosedaily.co/MINDPUMP Code: MINDPUMP — 25% off first month subscription Butcher Box — https://butcherbox.com/mindpump No code needed — Choose your free for life offer + $20 off: free sirloin tips for life, free chicken wings for life, or free ground beef for life Mind Pump Fitness Coaching — https://mindpumpfitnesscoaching.com 1.9 NASM CEUs 0:00 - Intro 2:26 - Best exercises and strategies for a crazy pump — the full breakdown 8:48 - Hydration with sodium & carbs — why supplements don't come close 13:20 - Full range of motion, 12–20 reps & superset strategies for maximum pump 16:46 - Flexing between sets & why chasing the pump can work against you 26:14 - Clow peptide stack — GHK, BPC-157, TB-500 & CPP for skin and recovery 38:01 - Why young trainers suck at training older people — the 5 reasons 45:13 - Breast milk, breastfeeding trends & Doug's 30-day cholesterol experiment with Dose 58:13 - Caller: Lindsay (Alberta) — building glutes on 1,600 calories, gets Muscle Mommy 1:04:16 - Caller: Alex (Florida) — military, weekend tracking inconsistency, crushing fatigue 1:13:29 - Caller: Brianna (North Carolina) — chronic overtraining, marathon mom, gets a Mind Pump coach 1:28:40 - Caller: Avery (Michigan) — fat intake while cutting, getting married in July
It was a heavy week in trail running, to say the least. Katie Schide officially withdraws from Hardrock as her foot injury rehab continues, and Kilian Korth faces season-ending surgery on a peroneus longus tendon tear that took place during this year's Cocodona 250.Then the Cam Hanes situation. After Hanes admitted to using banned peptide BPC 157 in an Instagram thread following his 2:39 Eugene Marathon, Sage Canaday filed a USADA tip. We break down the ethics of doping enforcement below the pro tier and what Cam's outsized influence on the sport means for any resolution.Plus: Rachel Entrekin's new multi-year Norda deal through 2029, Rachel Drake's record-shattering FKT on the West Grandeur Ascent, Will Peterson ending his Appalachian Trail FKT attempt at the Mason-Dixon line, ASICS opening a year-round UTMB training base in Les Houches, results from Leavenworth Trailfest and the Golden Trail World Series, plus a Twisted Fork Trail Festival preview.Partners:Precision Fuel and Hydration - use code SINGLETRACK at checkout for 15% off your next orderNorda - check out the 005: the lightest, fastest, most stable trail racing shoe ever madeRaide - Making equipment for efficient human-powered movement in the mountains Janji - premium trail running apparelSupport the show
In this episode of The Champion Living Podcast, Doug sits down with Eric Lore of Lore Fitness to break down the truth behind peptides, GLP-1 medications, recovery protocols, blood work, gut health, and real performance optimization. The fitness industry is flooded with misinformation around compounds like BPC-157, TB500, semaglutide, and GLP-based therapies. Eric explains what these compounds actually do, where they may help, the risks involved, and why foundational health habits still matter most. The conversation also dives into inflammation, injury recovery, nervous system function, nutrition, blood markers, and the future of human performance optimization. Whether you're an athlete, outdoorsman, or someone trying to improve your health, this episode delivers a balanced conversation around one of the fastest-growing topics in fitness and recovery. Huge thank you to our sponsors for supporting the show. Shoutout to Barstow Pro Rodeo. If you're looking for some of the best rodeo gear in the game, make sure you check them out and use discount code BARSTOWCHAMP26 to save on your order. And to the RodeoNow app, one of the best ways to stay up to date with rodeo news, standings, content, and everything happening in the western industry. Download today in the Apple App and Google Play store for FREE!
In Part 2 of our peptide series, Piet sits down again with Vincent Ronquillo — biology researcher, CrossFit athlete and co-founder of Z-Peptides and Pharmazine — to break down the two most talked about recovery peptides in the game right now: BPC-157 and TB-500, otherwise known as the Wolverine Stack.BPC-157 was originally discovered in the stomach — the compound that protects your stomach lining from its own acid. Researchers found that when applied to injured tissue, it triggers angiogenesis — new blood vessel growth — directly at the injury site, accelerating the repair process. TB-500, a fragment of Thymosin Beta-4, works systemically, guiding cells to the injury location and driving them to repair. Together they form one of the most studied peptide combinations in preclinical tissue repair science — and one of the most popular in the athletic and recovery community.They also break down the Reboot Stack — the Wolverine Stack plus GHK-Cu, the copper peptide. Originally studied for skin, GHK-Cu stimulates collagen and elastin production, making it the third piece of the puzzle for more serious injuries. Think of it this way: BPC-157 starts the healing, TB-500 directs it, and GHK-Cu provides the quality collagen to rebuild it stronger.Piet shares his own experience using the Wolverine Stack to recover from a badly rolled ankle — running a desert trail half marathon just six weeks later. Vincent shares how it brought him back from a knee injury that had him questioning whether he'd ever compete again.This is not medical advice. Always consult a doctor before starting any peptide protocol — which is exactly what we set up for you through Pharos and Z-Peptides.Part 3 coming soon. Drop your questions in the comments. Interested in getting started with peptides through Pharos? We're launching in Palm Springs first with full medical guidance, doctor consultation and 503A compliant sourcing.Click the link for our bio-performance survey.
La creatina es el suplemento más vendido del mundo.Y hay una conversación que nadie en la industria quiere tener sobre ella y el cáncer.En este episodio Carlos Muñoz habla sin filtros con un experto en medicina de frontera sobre lo que realmente alarga la vida — y lo que te están vendiendo que no funciona.━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
In this episode the guys break down the 5 types of people who just can't build muscle — Confusion Karl, Easy Stevie, Too Much Mike, Stay Shredded Sally, and Weekend Warrior Wally — and why each archetype is failing. They also get into a wild twin study showing red light therapy produced 15% more muscle growth than training alone, the latest UFO disclosure news and their theories on what's really going on, creatine officially going mainstream with non-fitness people talking about it at dinner tables, BPC-157 viral cancer fears debunked, and an ivermectin study showing 84% clinical benefit in cancer patients. Then they coach live callers submitted through mplivecaller.com — Jonathan from Northern Ireland on low testosterone as an ex-pro rugby player, Lindsay from Georgia on reverse dieting as a sleep-deprived nurse and mom of two, Rob from Connecticut on off-season strategy as a pro basketball player in Italy, and Charissa from Pennsylvania on building muscle without a traditional bulk and cut cycle. MAPS 15 BOGO — https://maps15bogo.com Buy 1 get 1 FREE — limited time (all 7 MAPS 15 programs same price) Sponsors: Eight Sleep (Pod 5 Ultra) — https://eightsleep.com/mindpump Code: MINDPUMP — Up to $350 off the Pod 5 Ultra. Memorial Day Sale running May 14 – June 12. Kion (creatine monohydrate) — https://getkion.com/mindpump 20% off — automatically applied at checkout, no code needed Joovv (red light therapy) — https://joovv.com/mindpump Code: MINDPUMP — $50 off your first purchase Submit a live caller question: https://mplivecaller.com Mind Pump Store: https://mindpumpstore.com Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia 0:00 - Intro 2:23 - 5 types of people who can't build muscle 3:22 - Type #1: Confusion Karl — why muscle confusion kills gains 9:39 - Type #2: Easy Stevie — the person who never pushes themselves 11:19 - Type #3: Too Much Mike — the overtraining fanatic 14:01 - Type #4: Stay Shredded Sally — eating too little to ever build 18:09 - Type #5: Weekend Warrior Wally — perfect Monday–Friday, disaster on weekends 23:34 - Red light therapy twin study — 15% more muscle growth in 12 weeks 29:26 - UFO disclosure — government releases star-shaped craft video, interdimensional theories 36:05 - Kansas basketball player blames creatine for cramping — debunked 39:15 - Creatine is now mainstream — ER doctors, nurses & non-fitness people talking about it 46:44 - BPC-157 viral cancer fear — is it actually dangerous? 51:33 - Ivermectin + Fenbendazole cancer study — 84% clinical benefit rate 55:09 - Importance of Sleep 56:17 - Caller: Jonathan (Northern Ireland) — ex-pro rugby player, low testosterone, overtrained 1:09:40 - Caller: Lindsay (Georgia) — nurse, postpartum, 1600 calories, scale creeping up 1:20:30 - Caller: Rob (Connecticut) — pro basketball player in Italy, off-season strategy 1:33:24 - Caller: Charissa (Pennsylvania) — building muscle without traditional bulk & cut
Book a free consultation call with Robert Sikes to break through your keto or low carb plateau right here: https://www.ketobodybuilding.com/callSurviving childhood morbid obesity and a fifteen year meth addiction takes total metabolic repair. In episode 886 of the Savage Perspective Podcast, host Robert Sikes sits down with Elaina Wang to share a powerful story of survival and deep health recovery. This discussion reveals how severe insulin resistance and bad food rules created a massive drug habit just to feel energy. Getting clean from drugs was brutal, but finding the keto diet and reversing type two diabetes naturally changed her entire life. You will learn exactly how real nutrition, heavy weight lifting, and targeted peptides can heal your brain, stop cravings, and fix chronic pain after years of severe trauma and addiction.Elaina's Hack Your Health Coaching: https://hackyourhealthcoaching.com/elaina-wangElaina's FB: https://www.facebook.com/KetoWang/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters0:00 - How I Survived Childhood Obesity & Severe Insulin Resistance1:09 - Why I Started Meth: The Shocking Truth About Energy & Fatigue2:01 - The Food Pyramid Myth: How Government Guidelines Fueled Addiction3:47 - Unbreakable Confidence: How to Build Self-Esteem When Overweight6:14 - The "Fat Meth Addict": Why Stimulants Couldn't Fix Type 2 Diabetes8:17 - Meth vs Cocaine: How Drugs Hijack Brain Dopamine & Sugar Cravings11:08 - The Secret Life of a Functional Addict: Survival Tactics & Thefts13:36 - Toxic Relationships: Navigating Co-Dependency & Addiction Relapse17:03 - The Turning Point: Dodging the Cops & Deciding to Get Clean20:43 - Type 2 Diabetes Diagnosis at 24: Ignoring the Ultimate Warning Sign21:10 - Quitting Meth Cold Turkey: The Brutal Reality of Early Sobriety25:22 - Blood Sugar at 426: Why I Refused Insulin Due to Addiction Fears27:08 - Reversing Type 2 Diabetes Naturally with the Keto Diet28:24 - Keto & Neuroplasticity: The Ultimate Biohack for Addiction Recovery30:02 - Losing 80 Lbs Fast: Do Cigarettes Spike Your Blood Sugar?34:00 - Becoming a Keto Coach: The Evolution of Low-Carb & Carnivore Diets36:10 - Healing Trauma vs. Trauma Bonding: The Missing Link in Weight Loss41:17 - BPC-157 & TB-500: Can Peptides Cure Chronic Pain & Bursitis?45:13 - GLP-1 for Addiction: The Unbelievable Cure for Alcoholism & OCD49:02 - Semaglutide vs Tirzepatide: Which GLP Weight Loss Peptide is Best?51:49 - The Dark Side of Ozempic: Who Should NEVER Take GLP Peptides53:31 - 155 Lb Weight Loss Surgery: Is Medical Tourism in Tijuana Safe?57:11 - Tummy Tuck Complications: Hematomas, Wound Vacs & Honest Recovery1:01:01 - "Am I Too Old to Get Healthy?" The Ultimate Mindset Shift for Men & Women1:05:26 - Where to Find Elaina Wang: Coaching, Biohacking & Future Events
Your relationships are reshaping your biology in ways that diet and exercise alone cannot fix, and the science behind it will change how you think about longevity, metabolism, and what it actually means to be healthy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Molly Maloof, a physician and one of the most innovative voices in personalized medicine, functional medicine, and human performance. Since 2012, she has advised or consulted for over 50 companies across digital health, consumer health, and biotechnology. She pioneered a course on healthspan at Stanford University and founded Adamo Bioscience, a company dedicated to unlocking the science of love as a pathway to healing and human connection. Dr. Maloof brings a rare combination of clinical depth, biohacking credibility, and entrepreneurial range to one of the most overlooked conversations in longevity. Together, Dave and Dr. Maloof dig into the neurobiology of love and attachment, the hormonal drivers of the sex drive and pair bonding, and how chronic isolation wrecks your metabolism at the cellular level. They explore the cell danger response and how toxic relationships, mold exposure, and trauma can lock your cells into a self-protection mode that blocks healing. They also cover psychedelics as hormetic tools, oxytocin as nature's medicine, the placebo response, peptide therapy for mitochondrial repair and anti-aging, and why regenerative medicine is about to rewrite the rules of human lifespan. If you are serious about biohacking your body from the inside out, this episode is essential. You'll Learn: Why human connection is a biological necessity, not a lifestyle preference, and what isolation does to your mitochondria and metabolism How the three neurobiological drives of sex, romantic love, and attachment are wired into your hormones and what happens when they go wrong What the cell danger response is, why it gets stuck, and which peptides, supplements, and therapies help break the cycle How oxytocin drives wound healing, immune function, and the placebo response Why psychedelics work as hormetic love drugs and how they reproduce the neurobiology of romantic love The top peptides for mitochondrial repair, brain optimization, and telomere biology Why Dave and Dr. Maloof believe we have already reached longevity escape velocity How AI is accelerating precision medicine, protein folding breakthroughs, and the future of anti-aging therapeutics Why fasting, breathwork, neurofeedback, and somatic therapies all converge on the same biological reset mechanism How to build the adaptive capacity and bioenergetic reserves to bounce back from anything Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.com and use code DAVEPOD at checkout for 15% off. - Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out - Puori | Go to Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18 - Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Molly Maloof, Adamo Bioscience, Stanford University, personalized medicine, functional medicine, healthspan, longevity, biohacking, human performance, anti-aging, regenerative medicine, longevity escape velocity, cell danger response, mitochondria, mitochondrial health, oxytocin, vasopressin, dopamine, serotonin, neurobiology of love, attachment theory, pair bonding, sex drive, hormone replacement therapy, testosterone, estrogen, menopause, andropause, libido, female sexual dysfunction, relationship biology, social health, isolation, community, co-regulation, trauma healing, psychedelics, MDMA, psilocybin, ibogaine, ayahuasca, hormetic stress, social hormesis, neurofeedback, 40 Years of Zen, breathwork, nervous system regulation, HPA axis, cortisol, mast cell activation, histamine, long COVID, mold exposure, phospholipid therapy, glutathione, vitamin C, BPC-157, TB500, SS31, epothilone, SELANK, SEMAX, BDNF, telomere biology, telomerase, peptides, GLP-1, placebo response, wound healing, metabolism, continuous glucose monitoring, gut health, AI, precision medicine, supplements, brain optimization, neuroplasticity Resources: • Grab Molly's Book The Spark Factor: https://www.amazon.com/Spark-Factor-Supercharging-Optimizing-Feeling/dp/0063207206 • Learn More About Dr. Molly's Work: https://drmolly.co/ • Visit Your Healthspan Journey: https://yourhealthspanjourney.mystrikingly.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:28 – Intro 01:39 – COVID Isolation & Its Effects 03:11 – Science of Love & Hormones 04:24 – Psychedelics & Love Chemistry 09:22 – Cell Danger Response 11:07 – AI, Tech & Human Connection 13:20 – Social Connection as Medicine 20:50 – Placebo, Care & Psychedelics 24:49 – Altered States & Healing Modalities 30:09 – Peptides & Longevity Drugs 35:44 – Mast Cell & Personal Health Challenges 43:46 – Regenerative Medicine & The Future 46:17 – Longevity Escape Velocity 50:05 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Why do patients refuse statins backed by decades of data in millions of people yet eagerly inject peptides tested in fewer than 20? Emergency medicine physician and longevity practitioner Vikas Patel confronts this paradox head-on. In this episode, based on his KevinMD article "Why the FDA regulations on peptide therapy matter," he breaks down what compounds like BPC-157 actually promise, what the evidence really shows, and why the gap between anecdotal hype and clinical proof should concern both physicians and patients. You will learn how the erosion of trust in medicine through the COVID years fueled demand for unregulated therapies promoted on podcasts and social media, why physicians who take an absolutist stance risk pushing patients further from reliable guidance, and how reframing long-term statin data dramatically changes the risk conversation. Patel also shares his practical approach to meeting patients where they are without compromising scientific integrity, and why he believes at least a handful of popular peptides will eventually prove their worth if anyone bothers to study them. If you want to have smarter conversations with patients about peptide therapy and rebuilding trust, press play. Tune into our episode "2026 Cholesterol Guidelines: LDL goals, lipoprotein(a), and coronary calcium scoring," brought to you by Novartis Pharmaceuticals Corporation. For the first time in eight years, LDL cholesterol goals have changed, and preventive cardiologist Seth Baum says the new guidelines are a long-overdue course correction. He breaks down the new LDL targets for your highest-risk patients, why the LDL hypothesis should be retired in favor of the LDL fact, why lipoprotein(a) screening finally belongs in every patient's workup, what a coronary calcium score over 300 really means for how aggressively you treat, and how to talk to statin-skeptical patients without losing their trust. Listen now at KevinMD.com/cholesterol. VISIT SPONSOR → https://kevinmd.com/cholesterol Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended
Join us for a recap of the Cocodona 250 race - why and how Cam DNF'd, the importance of a race crew, Rachel Entrekin's record breaking finish, and more! Follow along: Instagram: https://www.instagram.com/cameronrhanes Twitter: https://twitter.com/cameronhanes Facebook: https://www.facebook.com/camhanes/ Website: https://www.cameronhanes.com Timestamps: 00:00:00 – Cam's DNF and Why Having a Race Crew is Important 00:08:12 – Cocodona Start Line 00:14:35 – Crown King, Running with Michael Versteeg, and How Cam Fell 00:29:41 – What Ultra Running Races Mean to Cam 00:46:05 – The Controversy Behind Peptides & BPC 517 01:03:52 – Women Athletes: Is Estrogen the Superpower? 01:14:43 – Surgery and Future Faces 01:23:01 – Upcoming Rivet's Bear Hunt & Aravaipa Running Thank you to our sponsors: Ketone IQ: https://www.ketone.com/Cam use code CAM for 30% off your first subscription Hoyt: http://bit.ly/3Zdamyv use code CAM for 10% off MTN OPS Supplements: https://mtnops.com/ Use code KEEPHAMMERING for 20% off Black Rifle Coffee: https://www.blackriflecoffee.com/ Use code KEEPHAMMERING for 10% your order Sig Sauer: https://www.sigsauer.com/ use code CAM10 for 10% off optics Grizzly Coolers: https://www.grizzlycoolers.com/ use code KEEPHAMMERING for 20% off
What really happens when everything is on the line? With security, public safety, and real-world threats dominating headlines right now, including the shooting at the white house correspondence dinner where you saw Dana White and others, this episode couldn't be more relevant. Join Nick Lamagna on The A Game Podcast: Real Estate Investing For Entrepreneurs for a RETURN appearance with one of the most unique and fascinating guests we've ever had on the show - Joe Scargill, an active U.S. Secret Service agent, Brazilian Jiu Jitsu black belt, and leader responsible for protecting high-level targets in some of the most high-pressure environments in the world. This isn't just a conversation about law enforcement—it's a deep dive into how to stay calm, think clearly, and execute when everything is at stake. Whether you're an entrepreneur, investor, athlete, or someone looking to perform at a higher level, the lessons in this episode will change how you approach pressure, risk, and decision-making. He is the man behind Academy Safe, a nonprofit organization dedicated to certifying martial arts schools with background checks, safety protocols and standards that protect students, kids and families training in gyms across the country. You can find him at A Force BJJ in Ponte Vedre, FL! You will want to hear his incredible story of what it really takes to operate at the highest level under the highest pressure every single day! While most people only see what happens on the surface, Joe shares rare insight into: ✅ How the Secret Service actually handles real-world threats ✅ How Jiu Jitsu trains your brain to make better decisions under pressure ✅ The honest truth about TRT, peptides and BPC-157 for aging athletes ✅ Why cooking at home may be the most underrated health hack you're ignoring ✅ How agents make split-second decisions under extreme pressure + more See the show notes to connect with all things Joe Scargill! Connect with Joe: Joe Scargill on Facebook Joe Scargill on Instagram Joe Scargill on Threads Joe Scargill on LinkedIn Connect with Academy Safe: academysafe.org Academy Safe on Facebook Academy Safe on Instagram Academy Safe on Youtube Academy Safe on TikTok Connect with A Force BJJ: A Force BJJ A Force BJJ on Instagram A Force BJJ on Facebook --- Connect with Nick Lamagna www.nicknicknick.com Text Nick (516)540-5733 Connect on ALL Social Media and Podcast Platforms Here FREE Checklist on how to bring more value to your buyers