Podcasts about bdnf

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Latest podcast episodes about bdnf

The Liz Moody Podcast
Ask the Doctors: Happiness Edition—The 9 Best Tips From The World's Leading Experts

The Liz Moody Podcast

Play Episode Listen Later Jul 9, 2025 61:12


I'm so excited to share today's episode with you because it's packed with so many actionable tips to help you cultivate more happiness in your everyday life—and understand what might be getting in the way of it. I'm joined by nine incredible leading happiness experts. We're diving deep into the truth about dopamine and serotonin—what they really are, and why dopamine might actually not want you to be happy. We explore why we often feel less satisfied even after getting exactly what we thought we wanted, and how the “when I get this, I'll be happy” mindset is secretly keeping us stuck.  In this episode, we get into: Dopamine & serotonin on happiness How our society prevents happiness Having purpose in life Happiness within our career Happiness with social media & news consumption Perfectionism on happiness & so much more! Check out the full episodes of The Liz Moody Podcast discussed today: Neuroscience Hacks For Optimizing Dopamine, Serotonin, Oxytocin, BDNF, And More with Nicole Vignola The REAL Reason You're Burnt Out (And Exactly How To Fix It) with Israa Nasir My Top Micro Habits: Proven Ways To Get Happier & Healthier In 5 Minutes Or Less with Liz Moody Anyone Can Become More Optimistic—Here's How with Dr. Sue Varma Why We Have No Work/Life Balance + How To Fix It with Simone Stolzoff The Hidden Elements of Happiness That No One Is Talking About with Gretchen Rubin 3 Things To STOP Doing In Your 20s & 30s To Be Happier, Healthier & Wealthier with Liz Moody The Seven-Minute Secret To Happiness That No One Is Talking About with Dr. Dacher Keltner Science-Backed Hacks to MAJORLY Reduce Stress When The World Gets Overwhelming with Dr. Jenny Taitz Ready to uplevel every part of your life? Order Liz's book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now!  Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome. To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. This episode is brought to you completely free thanks to the following podcast sponsors: AG1: visit DrinkAG1.com/LizMoody and get your FREE year supply of Vitamin D and 5 free travel packs today. LMNT: go to DrinkLMNT.com/LizMoody to get a free LMNT sample pack with any order. IQ Bar: Text LIZ to 64000 for 20% off all IQBAR products plus FREE shipping. OSEA: get 10% off your first order at oseamalibu.com with code LIZMOODY or LIZMOODY10. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast.  This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 345. Learn more about your ad choices. Visit megaphone.fm/adchoices

The mindbodygreen Podcast
605: The 9 pillars for a happier, healthier mind | Drew Ramsey, M.D.

The mindbodygreen Podcast

Play Episode Listen Later Jul 6, 2025 57:28


“Simple movements, taking care of your mental health, and building deeper connections— those are drivers of longevity,” explains Drew Ramsey, M.D. Drew Ramsey, M.D., board-certified psychiatrist, psychotherapist, and author, joins us today to explain how all of us can take simple and actionable steps to improve our mental health, including the importance of dreams, adding in more movement, plus:  - Ramsey's practice (~1:30)  - The drivers of the mental health epidemic (~3:10) - Exercise & BDNF (~10:!5) - The 9 tenets for better mental health (~17:30) - The importance of connection (~19:00) - Gender differences (~23:25) - Cultural shifts & alcohol consumption (~27:55)  - Cannabis & psychedelics (~30:00) - The importance of sleep & dreams (~35:00) - The power of nutrition (~42:00) - The role of supplements (~46:00) - How to unburden yourself (~48:50) - Purpose & spirituality (~50:05) Referenced in the episode:  - Follow him on Instagram (@drewramseymd)  - Check out his website (https://drewramseymd.com/)  - Pick up his book, Healing the Modern Brain  Thanks for listening to this special episode—brought to you by Solaray, the #1 vitamin and mineral supplement brand in health food stores. Try their Liposomal Multivitamin for Women today at 30% off. Visit Solaray.com and use code MINDBODYGREEN: http://solaray.com/liposomal-womensWe hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Vitality Explorer News Podcast

Sit to Stand Test & Surgical Vitality PodcastFIVE PRIMARY POINTS of this week's PODCAST* Tame the “Brain-on-Fire” ProblemRunaway neuro-inflammation accelerates multiple sclerosis, stroke, Alzheimer's and Parkinson's. Prioritize lifestyle tactics that cross the blood–brain barrier—sleep, anti-inflammatory diet, and stress control—while watching developments in next-gen brain-penetrant drugs.* Ice Is Medicine: Use Cold Exposure to Re-Route Energy Away from InflammationBrief, controlled cold stress (a 90-second cold shower in the morning, progressing to 3–5 min ice baths or cold plunges 2–3×/week) forces the body to burn calories for heat, starving inflammatory pathways and even improving auto-immune outcomes in animal models. Always clear major cold work with your physician first.* Move Before You Medicate for Depression & AnxietyA meta-analysis of 26 RCTs (>2,500 participants) shows exercise rivals—or beats—pharmacotherapy for mood disorders. Aim for a baseline of 30 min brisk walking or resistance work most days; any movement is better than none, and mixed aerobic + strength routines offer the strongest mental-health bump.* Inflammation in Your 20s Predicts Brainpower in Your 40sAn 18-year cohort study linked consistently high—or even slowly rising—CRP levels with poorer mid-life cognition. Action: get a baseline CRP, track it yearly, and deploy weight control, resistance training, and nutrient-dense, time-restricted eating (“eat less, eat less often”) to keep levels low.* Double-Down on Purpose & Gratitude—They're Biological Anti-InflammatoriesA strong life purpose lowers IL-6 and CRP, while daily gratitude practice calms the amygdala and drops TNF-α. Practical micro-habit: each week thank five people (voice or face-to-face), and block 15 minutes on Sunday to revisit your “why.” Pair with twice-weekly strength training to release anti-inflammatory myokines and boost BDNF for memory.Listen to the full podcast to learn more and please leave your comments below. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe

The School of Doza Podcast
Cellular Energy 101: How to Improve Mitochondrial Function Naturally

The School of Doza Podcast

Play Episode Listen Later Jun 30, 2025 31:02


Get 40% Off At-Home NAD Shots Want a powerful energy boost without leaving home? Shed delivers clinical-grade NAD+ shots straight to your door—no appointment needed. NAD supports cellular repair, brain function, and longevity, making it one of our go-to biohacking tools. Get 40% off your first order at tryshed.com with code NURSEDOZA.     In this episode of the School of Doza podcast, we go full Cellular Energy 101: How to Improve Mitochondrial Function Naturally. Nurse Doza breaks down the five most impactful ways to boost energy from the inside out—starting with sunlight and ending with glutathione. If you're tired, sluggish, or just want to age better, this episode is your roadmap. 5 KEY TAKEAWAYS Sunlight—especially morning light—activates your mitochondria to naturally boost energy. Resveratrol supplements (like MITOCHONDRIAC) trigger AMPK, improving mitochondrial function. NAD+ injections can stimulate ATP production and mitochondrial biogenesis. Fasting and insulin regulation are essential for mitochondrial health and longevity. Glutathione protects your mitochondria from free radical damage and oxidative stress. FEATURED PRODUCT Mitochondriac, featuring pure trans-resveratrol and quercetin, is designed to activate AMPK and enhance mitochondrial function, promoting cellular energy production and healthy aging—exactly what's needed to implement the strategies discussed in this episode. Try Mitochondriac TIMESTAMPS 00:00 START – Welcome to the energy episode 05:00 – What mitochondria actually do (and why they matter) 07:00 – Energy vs waste: the balance of ATP and byproducts 08:00 – Why sunlight is your mitochondria's best friend 11:00 – Red light therapy and how it mimics the sun 12:00 – Resveratrol: how it fuels your cells 14:00 – The AMPK gene, explained simply 16:00 – Autophagy and mitochondrial biogenesis 17:00 – NAD+ therapy: weekly injections, daily energy 19:00 – The electron transport chain 101 22:00 – Mitochondrial enzymes that need NAD+ to function 24:00 – Regulating insulin and why fasting helps 27:00 – Ketones and caloric restriction for brain health 30:00 – The role of glutathione in detoxifying your cells 32:00 – Nurse Doza's 5-part mitochondrial optimization routine RESOURCES MENTIONED Red and Near-Infrared Light and Mitochondrial ATP/ROS Regulation NIR Light Reduces Cell Death in Parkinson's Disease Models Red Light Therapy and Mitochondrial Benefits Resveratrol and AMPK Activation Mitochondria, NAD+, and the Electron Transport Chain Ketones, BDNF, and Fasting Benefits Glutathione as a Mitochondrial Antioxidant SLC25A39 and GSH Transport into Mitochondria

Vibes Ai
5 min Power Nap: Sleep (Guided) - Cognitive Fitness Vibe

Vibes Ai

Play Episode Listen Later Jun 30, 2025 7:32


Transform your midday slump into peak performance with this scientifically-engineered restorative audio experience featuring our precision-tuned therapeutic frequency matrix. This 5-minute guided soundscape combines cutting-edge neuroscience with ancient healing frequencies to deliver maximum cognitive restoration.Our Therapeutic Frequency Stack:- 40Hz - Gamma wave entrainment for enhanced brain clearance, memory consolidation, and neural synchronization- 256Hz - Root chakra frequency promoting grounding and physical restoration- 285Hz - Cellular repair frequency supporting tissue regeneration during rest- 288Hz - Harmonic bridge frequency enhancing overall system balance- 320Hz - Solar plexus activation for renewed energy and confidence- 341.3Hz - Heart coherence frequency promoting emotional balance- 384Hz - Third eye resonance supporting intuitive clarity- 3Hz Binaural Beat - Delta wave induction for rapid sleep onset and deep restorationTop 3 Power Nap Usages:1. The 3PM Performance Crash - When post-lunch fatigue threatens your productivity and that important deadline looms. Studies show this timing aligns with natural circadian dips, making it ideal for a restorative reset.2. Pre-Presentation Power-Up - Before high-stakes meetings, presentations, or creative sessions when you need peak mental clarity and confidence. Research confirms 20-minute naps boost problem-solving abilities by up to 40%.3. Shift Work Recovery - For healthcare workers, first responders, or anyone managing irregular schedules. Strategic power naps help recalibrate disrupted circadian rhythms and maintain cognitive sharpness during critical hours.Our dynamic frequency layering reduces sleep latency by 15-38%, increases slow-wave sleep efficiency, and lowers cortisol by 22%. Wake refreshed without grogginess, with enhanced memory, sharper focus, and renewed energy to conquer your day.Based on peer-reviewed neuroscience research. Individual results may vary. For extended sessions and personalized soundscapes, explore our premium Restorative Audio collection.Send us a textSupport the show

Vibes Ai
15 min Power Nap: Sleep (Unguided) - Cognitive Fitness Vibe

Vibes Ai

Play Episode Listen Later Jun 30, 2025 15:28


Transform your midday slump into peak performance with this scientifically-engineered restorative audio experience featuring our precision-tuned therapeutic frequency matrix. This 15-minute soundscape combines cutting-edge neuroscience with ancient healing frequencies to deliver maximum cognitive restoration.Our Therapeutic Frequency Stack:40Hz - Gamma wave entrainment for enhanced brain clearance, memory consolidation, and neural synchronization256Hz - Root chakra frequency promoting grounding and physical restoration285Hz - Cellular repair frequency supporting tissue regeneration during rest288Hz - Harmonic bridge frequency enhancing overall system balance320Hz - Solar plexus activation for renewed energy and confidence341.3Hz - Heart coherence frequency promoting emotional balance384Hz - Third eye resonance supporting intuitive clarity3Hz Binaural Beat - Delta wave induction for rapid sleep onset and deep restorationTop 3 Power Nap Usages:The 3PM Performance Crash - When post-lunch fatigue threatens your productivity and that important deadline looms. Studies show this timing aligns with natural circadian dips, making it ideal for a restorative reset.Pre-Presentation Power-Up - Before high-stakes meetings, presentations, or creative sessions when you need peak mental clarity and confidence. Research confirms 20-minute naps boost problem-solving abilities by up to 40%.Shift Work Recovery - For healthcare workers, first responders, or anyone managing irregular schedules. Strategic power naps help recalibrate disrupted circadian rhythms and maintain cognitive sharpness during critical hours.Our dynamic frequency layering reduces sleep latency by 15-38%, increases slow-wave sleep efficiency, and lowers cortisol by 22%. Wake refreshed without grogginess, with enhanced memory, sharper focus, and renewed energy to conquer your day.Based on peer-reviewed neuroscience research. Individual results may vary. For extended sessions and personalized soundscapes, explore our premium Restorative Audio collSend us a textSupport the show

The Concussion Nerds Podcast
EP 89: Unlocking Brain Power: Discovering Photobiomodulation with Chris Garvin

The Concussion Nerds Podcast

Play Episode Listen Later Jun 30, 2025 28:21


What if healing the brain wasn't just about rest and rehab—but light? Most people think of concussion treatment as pacing, physio, maybe some cognitive rehab… but what if we've been missing a powerful, science-backed tool this whole time? Let's be real: Photobiomodulation sounds like something straight out of a sci-fi film. And if you're a clinician or someone on a healing journey, you might be wondering—how could a helmet that shines light on your head actually make a difference? In this episode of the Concussion Nerds Podcast, Natasha is joined by Chris Garvin from Neuronic, a cutting-edge neurotech company that's changing how we support the brain using light. Together, they break down the science of photobiomodulation in a way that's actually understandable—and explore how it's being used to help people with persistent concussions, cognitive decline, and more.     BY THE TIME YOU FINISH LISTENING, YOU'LL DISCOVER: What photobiomodulation actually is—and how Neuronic's device is using it to improve brain function How red light therapy has evolved beyond skincare to support concussion recovery and neurodegenerative care The real-life stories of patients and families seeing life-changing shifts through this technology What new research says about boosting BDNF (aka brain fertilizer) without needing intense aerobic exercise     This episode is a must-listen for clinicians who want to stay on the cutting edge of evidence-informed care—and for anyone on a healing journey who's curious about non-invasive tools that can support real recovery. If you've never heard of Neuronic or photobiomodulation before, prepare to have your mind (and brain) blown. Let's connect!   Instagram:  @concussionnerds https://www.instagram.com/concussionnerds/ @natasha.wilch https://www.instagram.com/natasha.wilch/ Email: hello@natashawilch.com Website: https://www.natasha-wilch.com Learn how to connect & understand your nervous system so you can have greater outcomes in your health & healing journey: Grab a copy of the workbookhttps://www.natashawilch.com/understanding-connecting-your-nervous-system-1   Join the Clinician's Edge to have Your Weekly Taste of Neuro Wisdom  here: https://www.natashawilch.com/clinicians-edge   Join the Concussion Mini School and Membership! Get the support and resources you need for concussion recovery: Mini School: https://www.natashawilch.com/concussion-mini-school Membership: https://www.natashawilch.com/concussion-mini-school-the-membership  

Dying to Ask
Mastering Movement Bites With Jessica Schatz

Dying to Ask

Play Episode Listen Later Jun 27, 2025 27:51


Need a pick-me-up? Skip the coffee and try a movement bite. Jessica Schatz is a celebrity trainer and biomechanics and ProACTIVE Aging expert. She's trained professional athletes, Broadway stars and Hollywood actors for decades. Those athletes and performers need to maintain energy to perform. Jessica says the key to maintaining energy and aging well isn't destroying yourself in a two-hour gym workout. It's a lot easier than that. It's incorporating five-minute exercise breaks frequently into your day. Even 30 seconds of jumping jacks, pushups or squats can go a long way. Jessica calls them movement bites. "They increase your blood flow. They increase your heart rate. And they start to release these proteins, these Myokines, and they also release a protein called BDNF, Brain Derived Neurotrophic Factor. It's like fertilizer for your brain," Schatz said. It's good news for anyone not crazy about chasing the elusive runner's high. Creating a positive neurfeedback loop doesn't have to leave you exhausted. It just needs to be consistent. "You're literally teaching yourself to foster a relationship with movement that's positive," Schatz said. Follow Jessica: Facebook: @thecoreexpert Instagram: @TheCoreExpert YouTube: @TheCoreExpert On this Dying to Ask: A deep dive into the science of hope molecules 5 movement bites you can do sitting in your car or at your desk How to plan your own "pick-me-ups" to improve mood and energy And what it's like to be a celebrity trainer to stars like Ashley Olsen and NBA players Other places to listen CLICK HERE to listen on iTunes CLICK HERE to listen on Stitcher CLICK HERE to listen on Spotify See more coverage of top California stories here | Download our app | Subscribe to our morning newsletter | Find us on YouTube here and subscribe to our channel

Gente Interesante
Phil Hugo y Oriol Roda DESTROZAN mitos de la dieta cetogénica

Gente Interesante

Play Episode Listen Later Jun 20, 2025 257:23


Biohacker Babes Podcast
Decoding PMDD with Britney Marsden: Root Causes, Trauma & the Truth About Your Cycle

Biohacker Babes Podcast

Play Episode Listen Later Jun 16, 2025 65:42


In this powerful episode we sit down with Britney Marsden, also known as "The PMDD Chick," to explore the multifaceted experience of living with Premenstrual Dysphoric Disorder (PMDD). Britney opens up about her personal journey with PMDD — from misdiagnosis and confusion to self-advocacy and empowerment. She dives into the many possible root causes of PMDD, including hormonal imbalances, gut health, nutrient deficiencies, and environmental factors, emphasizing that PMDD isn't just “in your head” — it's often the result of complex physiological and psychological interactions. One key theme throughout the conversation is the role of trauma, and how unresolved emotional wounds can manifest or intensify PMDD symptoms. Britney also offers heartfelt and empowering advice to women who are struggling: from finding the right practitioners to the importance of self-compassion, community, and nervous system regulation. Her message is both hopeful and validating, reminding listeners that healing is possible — and that they're not alone.Britney Marsden, known as "The PMDD Chick," is a dedicated Women's Health Coach specializing in Premenstrual Dysphoric Disorder (PMDD). Drawing from her own experience overcoming severe PMDD, she has become a trusted source of support and knowledge for women facing this often misunderstood condition. As a qualified Women's Health Coach, Britney empowers women to identify and address factors that exacerbate PMDD symptoms. Empowering women to identify contributing factors that may exacerbate PMDD symptoms, Britney offers holistic, personalized solutions through her online PMDD programs, which provide practical strategies and insights to help women manage and alleviate their symptoms effectively.SHOW NOTES:0:39 Welcome to the show!3:18 About Britney Marsden4:28 Welcome Britney to the podcast!5:39 What is PMDD?7:12 Her diagnosis & journey through12:36 Traditional solutions for PMDD14:09 Understanding the Hormonal Cycle17:04 Genetic predispositions for PMDD18:18 BDNF, Trauma & ADD correlations19:17 MCAS, Histamine & Hidden Infections22:07 The #1 contributor to PMDD25:56 Talk therapies & ISDTP31:05 *MY ALIGN MAT*33:05 Plant Medicines & Microdosing37:04 Her root cause spinal infection40:41 POTS, MCAS & Sinus Tachycardia42:49 How she persevered & turned a corner50:25 Supplements & Biohacks for PMDD53:24 Healing gut dysbiosis55:57 Coexisting comorbidities1:00:28 Her final piece of advice1:03:40 Where to find her1:04:57 Thanks for tuning in!RESOURCES:Website: www.thepmddchick.comHer Health Confessions PodcastTikTok: https://www.tiktok.com/@thepmddchickInstagram: https://www.instagram.com/thepmddchick/Intensive Short-Term Dynamic PsychotherapyMyAlignMat - code: BIOHACKERBABESPuori - Discount code: BIOHACKERBABESOur Sponsors:* Check out Puori: https://Puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

Vibes Ai
15 min Brain Reboot: Sound Therapy For Brain Rot (Unguided) - Cognitive Fitness Vibe

Vibes Ai

Play Episode Listen Later Jun 9, 2025 15:27


Brain Reboot is a Brain Rot remedy that is a focused restorative audio experience designed to counter the cognitive effects of digital overwhelm and information overload through precisely calibrated frequency combinations.This science-backed audio therapy integrates:- 40Hz gamma frequencies to enhance neural synchronization and stimulate BDNF production- Beta wave frequencies (13-30Hz) to improve focus and analytical thinking- Theta waves (4-7Hz) to facilitate emotional regulation and creative problem-solving- Solfeggio frequencies including 417Hz and 528Hz to promote cellular repairThe composition progresses through three strategic phases:- Clearing - Dissolves mental fog and restores attentional capacity- Synchronizing - Realigns neural oscillations disrupted by digital multitasking- Strengthening - Enhances cognitive resilience and executive functionClinical studies show that consistent listening for 20 minutes daily can improve attention span by 35% and reduce mental fatigue by 50% after four weeks.Experience renewed mental clarity, improved memory consolidation, and enhanced focus as this acoustic intervention helps recalibrate your brain's natural rhythms in our hyper-digital world.Send us a textSupport the show

Vibes Ai
5 min Brain Reboot: Sound Therapy For Brain Rot (Guided) - Cognitive Fitness Vibe

Vibes Ai

Play Episode Listen Later Jun 9, 2025 7:34


Brain Reboot is a Brain Rot remedy that is a focused restorative audio experience designed to counter the cognitive effects of digital overwhelm and information overload through precisely calibrated frequency combinations.This science-backed audio therapy integrates:- 40Hz gamma frequencies to enhance neural synchronization and stimulate BDNF production- Beta wave frequencies (13-30Hz) to improve focus and analytical thinking- Theta waves (4-7Hz) to facilitate emotional regulation and creative problem-solving- Solfeggio frequencies including 417Hz and 528Hz to promote cellular repairThe composition progresses through three strategic phases:- Clearing - Dissolves mental fog and restores attentional capacity- Synchronizing - Realigns neural oscillations disrupted by digital multitasking- Strengthening - Enhances cognitive resilience and executive functionClinical studies show that consistent listening for 20 minutes daily can improve attention span by 35% and reduce mental fatigue by 50% after four weeks.Experience renewed mental clarity, improved memory consolidation, and enhanced focus as this acoustic intervention helps recalibrate your brain's natural rhythms in our hyper-digital world.Send us a textSupport the show

Vibes Ai
5 min Brain Reboot: Sound Therapy For Brain Rot (Unguided) - Cognitive Fitness Vibe

Vibes Ai

Play Episode Listen Later Jun 9, 2025 7:27


Brain Reboot is a Brain Rot remedy that is a focused restorative audio experience designed to counter the cognitive effects of digital overwhelm and information overload through precisely calibrated frequency combinations.This science-backed audio therapy integrates:- 40Hz gamma frequencies to enhance neural synchronization and stimulate BDNF production- Beta wave frequencies (13-30Hz) to improve focus and analytical thinking- Theta waves (4-7Hz) to facilitate emotional regulation and creative problem-solving- Solfeggio frequencies including 417Hz and 528Hz to promote cellular repairThe composition progresses through three strategic phases:- Clearing - Dissolves mental fog and restores attentional capacity- Synchronizing - Realigns neural oscillations disrupted by digital multitasking- Strengthening - Enhances cognitive resilience and executive functionClinical studies show that consistent listening for 20 minutes daily can improve attention span by 35% and reduce mental fatigue by 50% after four weeks.Experience renewed mental clarity, improved memory consolidation, and enhanced focus as this acoustic intervention helps recalibrate your brain's natural rhythms in our hyper-digital world.Send us a textSupport the show

Biomécanique
#282 L'Expert N°1 du Cerveau : Ces habitudes détruisent votre mémoire (et provoquent Alzheimer)

Biomécanique

Play Episode Listen Later May 26, 2025 142:26


Le Dr Boris Dufournet est neurologue, spécialisé en neurologie intégrative, médecine métabolique et neurométabolique, avec une approche holistique centrée sur la prévention, la santé globale et la performance durable.https://docteurs-dufournet.com/https://www.youtube.com/@UC3LQDnUdIjIPvykIkZhBc6Ahttps://www.youtube.com/channel/UCOHmHVv5u_mle1HCYUUF_oAhttps://www.linkedin.com/in/borisdufournet/https://x.com/bdufournetCHAPITRES0:00 Introduction0:55 Comprendre les Facteurs de Risque4:42 Le Rôle du Sommeil5:31 Impact de l'Alimentation16:39 Génétique vs Épigénétique21:14 Prévention et Mode de Vie43:51 Test Génétique et Stress47:07 Stratégies de Prise en Charge48:26 Importance de l'activité physique53:48 Impact du BDNF sur la santé cognitive55:26 Rôle des écrans et de la passivité1:01:05 Effets du sucre sur les neurones1:05:15 Diabète cérébral et Alzheimer1:15:02 Vieillissement et perception de la santé1:18:01 Activités cognitives pour prévenir Alzheimer1:30:28 Ménopause et santé hormonale1:33:01 Hormones et risque d'Alzheimer1:35:45 Les limites de la supplémentation hormonale1:38:06 Risques des niveaux hormonaux excessifs1:40:33 La question des doses physiologiques1:42:59 L'importance du régime cétogène1:47:11 Nutrition et sport à travers l'histoire1:49:24 Les effets des glucides sur la santé1:53:33 Le régime cétogène thérapeutique1:58:09 Réflexions sur le métabolisme et les cétones2:02:59 Toxicité des glucides et micronutriments2:08:13 Les phyto-oestrogènes et la testostérone2:10:50 Rôle des fibres et du microbiote2:16:18 Précautions sur le micro-dosing2:21:00 Conclusion et perspectives futuresLIENS PODCASTS• Spotify : https://open.spotify.com/show/1yqDTNuuLcagrP3Z0jwBzz• Apple Podcasts : https://podcasts.apple.com/fr/podcast/biom%C3%A9canique/id1456142727• Youtube : https://www.youtube.com/@UCQlJ8F6VtTThflbkhdJmXWALIENS RÉSEAUX SOCIAUX & SITE• Instagram : https://www.instagram.com/biomecaniquepodcast/• Facebook : https://www.facebook.com/BiomecaniquePodcast/• Tiktok : https://www.tiktok.com/@biomecaniquepodcast• Discord : https://discord.gg/EAe8aKRJ9N• Website : https://biomecaniquepodcast.com• Newsletter : https://biomecaniquepodcast.com/Lettre Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Dr. Joseph Mercola - Take Control of Your Health
The Weight Training and Dementia Prevention Link - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later May 24, 2025 7:25


Story at-a-glance A study from Brazil's State University of Campinas found twice-weekly weight training for six months preserved brain regions vulnerable to Alzheimer's in older adults with mild cognitive impairment In this research, five of the 22 people in the resistance training group improved enough to no longer meet clinical criteria for cognitive impairment Exercise protects the brain through multiple mechanisms. It stimulates growth factors like BDNF, reduces inflammation, improves cerebral blood flow, and regulates stress hormones that contribute to cognitive decline For optimal longevity benefits, research suggests limiting strength training to 40 to 60 minutes weekly; exceeding 130 to 140 minutes may reverse health gains and even shorten your life Mind-body exercises like yoga and tai chi also benefit brain health. They lower cortisol, reduce anxiety, and improve executive function, attention, and processing speed

Life Coaching for Women Physicians
263: DNA-Informed Health and Fitness Strategies - Genetic Insights

Life Coaching for Women Physicians

Play Episode Listen Later May 21, 2025 28:36


The FIT Collective Genetic Insights Series – Episode 1Understanding Genetics, Stress, & Weight with Dr. Ali NovitskyDr. Ali Novitsky, board-certified in obesity medicine, kicks off a new series on how genetics influence health—especially stress responses and weight regulation. She opens with a personal story: during college, despite eating well and exercising, she gained 20 pounds in three months. Genetic testing later revealed a variant in her cortisol receptor gene, causing her body to release excess cortisol under stress—leading to high blood sugar, insulin resistance, and ultimately, weight gain.Cortisol plays a central role in stress response and metabolism. While helpful in short bursts, chronic elevation from ongoing stress can disrupt insulin function, making weight loss more difficult for those with specific genetic variants. For Dr. Novitsky, managing stress—not restricting calories or increasing workouts—was the key to reversing her weight gain.About 30% of people carry this cortisol receptor variant. In her 2022 genetics cohort, 80% tested positive. This highlights the power of personalized health strategies rooted in understanding one's unique genetic makeup.Dr. Novitsky uses Genomind's Mental Health Map, a genetic test offering insight into stress, mood, and focus. One critical gene it reports on is COMT, which affects dopamine breakdown. Individuals with the MetMet variant retain more dopamine—great for focus, but often sensitive to stress. Those with ValVal clear dopamine quickly, leading to impulsivity and a higher likelihood of ADHD.Another important factor is BDNF (brain-derived neurotrophic factor), a gene linked to memory, cognition, and mood. Those with a BDNF variant often need regular exercise to optimize brain health and emotional balance.The takeaway? Health isn't one-size-fits-all. For some, gentle exercise, high-quality sleep, and stress reduction may be far more effective than intense workouts or calorie restriction. Dr. Novitsky's approach integrates genetic awareness into actionable wellness strategies.She also introduces her four-week genetics program, which includes one-time testing, personalized supplement recommendations, and coaching based on individual results. Participants receive a lifelong health blueprint.Future episodes will explore the genetics of eating behaviors, including cravings and satiety. Listeners are encouraged to tune in and learn how DNA influences decisions, habits, and long-term health.Timestamps00:00:00 - Introduction and Personal Story00:01:00 - Understanding Cortisol and Stress00:04:00 - Genetic Testing Insights00:05:30 - Cortisol and Weight Management00:08:00 - COMT Variants and Dopamine00:10:00 - Dopamine Receptor Genes00:11:00 - Strategies for Managing Genetics00:12:00 - Genetics Program Announcement00:13:00 - Custom Recommendations Based on Genetics00:15:00 - The Role of Serotonin and Oxytocin00:16:00 - Genetic Influences on Eating Behaviors00:18:00 - Stress Response and Emotional Eating00:20:00 - The Importance of Awareness00:22:00 - BDNF and Exercise00:23:00 - Micro-Dosed Lithium and Mood00:24:00 - Genetic Predispositions to Worry00:25:00 - Empowerment Through Genetic Awareness00:26:00 - Preview of Next Episode on Eating Genetics00:27:00 - Enrollment for Genetics Program00:28:00 - Closing RemarksWork with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠⁠⁠⁠⁠Enroll TODAY⁠⁠⁠⁠⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠⁠⁠⁠⁠Enroll HERE⁠⁠⁠⁠⁠⁠• The Fit Collective® x InBody USA/Canada – Get 15% off select models. ⁠⁠⁠⁠⁠⁠Click HERE⁠

The MindHealth360 Show
77: Dr. Achina Stein: transforming mental health with Functional Medicine psychiatry

The MindHealth360 Show

Play Episode Listen Later May 21, 2025 65:39


In this captivating online presentation from the IMMH 2023 conference, board-certified psychiatrist Dr. Achina Stein reveals how the intersection of functional medicine, gut restoration, and psychiatry can lead to lasting healing for depression, anxiety, and other mental health challenges. She explains why the journey takes dedication and time, why psychiatry provides an ideal setting, and why it's worth the effort. She also delves into very concrete clinical advice on the basics of how to implement functional medicine psychiatry.    Dr. Achina Stein is a board-certified psychiatrist with over 25 years of clinical experience and serves as the Clinical Director of the Healing Depression Project. Also a certified practitioner with the Institute for Functional Medicine (IFMCP) and a distinguished fellow of the American Psychiatric Association, Dr. Stein was awarded the Exemplary Psychiatrist Award by the National Alliance on Mental Illness. Author of the best-seller What If It's Not Depression, she explains how diet and lifestyle changes - including gut restoration and the 5R protocol - can significantly improve depression, anxiety, and mental health. In this comprehensive presentation, Dr. Stein reveals why standard psychiatric care often falls short by relying on a “silver bullet” approach, the limitations of medications, and why functional medicine offers a revolutionary path forward in psychiatry and mental health treatment.   In this episode, discover: Who benefits most from functional medicine and why it's ideal for patients open to diet and lifestyle changes. Why functional medicine analyses food diaries, bowel movements, sleep patterns, exercise, toxin and mould exposure and physical exam/gait analysis in evaluations alongside more conventional  psychiatric care. Why a diagnosis isn't always needed for treatment, and why changes to diet and lifestyle can treat conditions before they fully manifest. The link between complex chronic illness and mental health symptoms. The intrinsic connection between depression and inflammation. Other often overlooked root causes of depression and anxiety, including certain medications (e.g., Chantix, Accutane), low cholesterol, low Omega-3, low Vitamin D, thyroid issues, lupus and other autoimmune conditions, and hypoglycemia. Why antidepressants may not always improve symptoms and the potential downsides of their use. The importance of addressing infections, toxins, oxidative stress, hormone imbalances, digestive issues, blood sugar levels, and circadian rhythm in treatment. The 5R protocol (Remove, Replace, Reinoculate, Repair, Rebalance) and its role in restoring gut health for better mental health. Insights from the Dr. Hyman Questionnaire on how chronic toxicity impacts mental health. Why the gut-brain axis is a crucial missing link in treating depression, the mental health risks of gut permeability (leaky gut), and the critical role of diet in maintaining gut and brain health. Ways to strengthen the gut-brain connection and increase BDNF levels through HIIT, fasting, and cold exposure for mental health benefits. The crucial role of exercise in detoxification. Top dietary recommendations for improving depression, anxiety and mental health, including foods to add (vegetables, eggs, beef, fish, quinoa, nuts, seeds, fermented foods) and foods to avoid (caffeine, sugar, dairy, gluten).  

Pushing The Limits
The power of KAATSU Training with Sandy Nelson

Pushing The Limits

Play Episode Listen Later May 4, 2025 47:16


Welcome back to Pushing the Limits for another insightful episode. Today, we dive into Kaatsu Training with Sandy Nelson, exploring how this blood flow restriction technique boosts bone density, muscle growth, and brain health for older adults and athletes. Key Points: Research suggests Kaatsu Training helps older adults with osteopenia by improving bone density. It seems likely that Kaatsu Training increases IGF-1 and BDNF, supporting muscle and brain health. The evidence leans toward Kaatsu Training offering neuroprotection, likely via BDNF. Kaatsu Training appears to enhance athlete performance, aiding recovery and strength. What is Kaatsu Training? Kaatsu Training, also known as Blood Flow Restriction (BFR) training, is a method where special bands partially restrict blood flow to the limbs during exercise. This creates a hypoxic environment in the muscles, promoting growth and strength with lighter loads. It was developed in Japan by Dr. Yoshiaki Sato and is used for both rehabilitation and performance enhancement. Benefits for Older Adults and Osteopenia For older adults, Kaatsu Training can help combat osteopenia, a condition with low bone density. Studies suggest it can maintain or increase bone density, reducing fracture risk and supporting mobility, especially for those with joint issues like osteoarthritis. Its low-impact nature makes it suitable, allowing strength gains without excessive joint stress. Impact on IGF-1, BDNF, and Neuroprotection Research indicates Kaatsu Training increases Insulin-like Growth Factor 1 (IGF-1), vital for muscle and bone health, and Brain-Derived Neurotrophic Factor (BDNF), important for brain health. This likely contributes to neuroprotection, potentially reducing neurodegenerative disease risk by supporting cognitive function. Benefits for Athletes For athletes, Kaatsu Training can enhance performance by improving muscle strength and hypertrophy with lighter weights. It can also aid recovery by promoting growth hormones, reducing muscle damage, and allowing more frequent, intense training, benefiting Olympians and professional athletes. Use code "Nelson" at Kaatsu.com for 10% off to start incorporating this training Sandy Nelson Bio  "Never before have I seen a modality that gives such a robust hormonal response and promotes the biochemical factors we need  to stay strong and sharp as we age." As a KAATSU Certified Coach, Sandy specializes in helping build and maintain your strength and stamina over 50.  She also helps healthcare professionals implement KAATSU within their practices and with their clients.​​​​​​​  

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
DO NOT Fail This Brain Test (For Early Dementia)

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later May 2, 2025 5:40


Memory loss is not the only early sign of dementia! Other common cognitive decline symptoms involve the speed at which you process information and your attention and focus.To perform the clock drawing test for dementia, set a timer for 30 seconds and draw a clock with the time set at 10 minutes after 11. To evaluate your results for any dementia risk factors, examine the following:•Were any numbers jumbled or missing?•Did you write all 12 numbers?•Were the numbers spaced correctly?•Were the hands of the clock facing the right direction?•Did you reverse the hour and the minute hands?•Were you unable to complete this in 30 seconds?The clock drawing test is one of the most sensitive indicators of early cognitive deficits and is considered more accurate than memory tests.If you didn't pass this test or you made a mistake, don't worry! You can do many things to support brain health and prevent or reverse dementia.Sugar shrinks your brain, especially the hippocampus, which controls memory. Chronic stress and poor sleep can also contribute to the problem. If you notice any signs of early dementia, increasing BDNF (brain-derived neurotrophic factor) is vital. BDNF helps grow brain tissue and prevents cognitive problems, as well as other issues like depression. Here are the best ways to increase BDNF:•Intermittent fasting •Cold therapy •Deep sleep •Learning difficult tasks or skills•High-intensity interval trainingKetones can also help reverse dementia and protect your brain against cognitive decline. A low-carb diet can increase ketones and has even been shown to reverse diabetes in 10 weeks!MCT oil, coconut oil, and ketone supplements can also provide the brain with ketones. To remain in ketosis, only consume a moderate amount of protein!

Intelligent Medicine
ENCORE: Food for Thought: Enhancing Mental Health through Nutrition, Part 1

Intelligent Medicine

Play Episode Listen Later Apr 29, 2025 27:46


Dr. Drew Ramsey is a pioneer in the emerging field of Nutritional Psychiatry and author of "Eat to Beat Depression and Anxiety: Nourish Your Way to Better Mental Health in Six Weeks." Dr. Ramsey reviews the remarkable research that has demonstrated the efficacy of diet for improving mental health outcomes. The foods we eat impact our brain function for better or for worse, delivering essential nutrients, fostering a healthy microbiome, combatting inflammation, encouraging neuroplasticity, and supporting neurotransmitters. He is co-developer of the Antidepressant Food Scale that rates foods based on their potential to support well-being. He is also director of the Brain Food Clinic, which offers integrative psychiatric care incorporating “dietary assessment and food prescription along with coaching, meal planning, and hands on skill building in your kitchen.” He believes that no single diet offers a panacea for mental health optimization, but that replacement of ultra-processed food with nutrient-dense alternatives offers the most benefits with ease of compliance. 

The Human Upgrade with Dave Asprey
The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1275

The Human Upgrade with Dave Asprey

Play Episode Listen Later Apr 25, 2025 66:22


You've probably heard of HIIT—but have you heard of “REHIT?” This isn't just another workout trend...it's a new science-backed way to train with maximum efficiency and zero wasted time. If you're still jogging, you're wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that's obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase• 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You'll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you're traveling or don't have access to the tech Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE' for a discount – https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey's Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Human Upgrade with Dave Asprey
The End of Cardio? Burn Fat & Boost VO₂ Max in Just 8 Minutes a Week – with REHIT | Ulrich Dempfle : 1274

The Human Upgrade with Dave Asprey

Play Episode Listen Later Apr 25, 2025 66:08


You've probably heard of HIIT—but have you heard of “REHIT?” This isn't just another workout trend...it's a new science-backed way to train with maximum efficiency and zero wasted time. If you're still jogging, you're wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that's obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase • 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But what is it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows exactly how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You'll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you're traveling or don't have access to the tech Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE' for a discount – https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey's Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

From the Spectrum: Finding Superpowers with Autism
Autism, Sensory Map & Serotonin

From the Spectrum: Finding Superpowers with Autism

Play Episode Listen Later Apr 21, 2025 31:52 Transcription Available


In this episode, we explore the critical role of serotonin in shaping sensory maps within the brain, a process vital for interpreting sensory input and navigating the world. Serotonin, a neurotransmitter and neuromodulator synthesized from the aromatic amino acid tryptophan, influences brain development by fine-tuning sensory systems. It modulates neuronal growth, synaptic connections, and plasticity, which are essential for creating accurate sensory maps in regions like the somatosensory cortex, visual cortex, and auditory cortex. These maps serve as blueprints for processing touch, vision, and sound, with serotonin regulating the pruning of connections in the thalamus and cortex to ensure precise sensory wiring.The episode also explores the broader biological implications of serotonin, emphasizing its role in both prenatal and postnatal development. Maternally derived serotonin, supplied via the placenta from the peripheral and enteric nervous systems, significantly influences fetal brain development, affecting proliferation, differentiation, and neuronal migration in sensory regions. Postnatally, serotonin continues to support sensory integration and mood regulation, working alongside oxytocin to facilitate bonding and stress buffering. We explore environmental factors, such as stress and modern lighting, on serotonin synthesis and the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol release. Daylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism0:00 Chroma Light Devices, use "autism" for a 10% discount03:12, Sensory Map Introduction and Serotonin's Role, The episode introduces sensory maps, neural blueprints that help the brain interpret sensory inputs like touch, vision, and sound, 04:30, Serotonin's Developmental Impact, Serotonin fine-tunes sensory systems by modulating neuronal growth, synaptic connections, and plasticity, creating precise sensory maps in the somatosensory, visual, and auditory cortices,06:04, Serotonin and Sensory Processing (Visual), Serotonin, sensory processing in the visual cortex08:29, Critical Periods and Neuroplasticity, sensory neurons and connections, pruning10:00, Brain Regions and Serotonin's Mechanisms, Serotonin, axonal guidance, neurogenesis, and migration via microtubules, brain-derived neurotrophic factor (BDNF), glutamate and GABA12:55, Serotonin and Sensory Processing (Somatosensory),13:51, Serotonin and Sensory Processing (Auditory),14:52, Stress and the HPA Axis, Cortisol, circadian rhythms and cortisol spikes, modern environments,16:16 Daylight Computer Company, use "autism" for a $25 discount20:38, Maternal Serotonin and Prenatal Influence; Postnatal Serotonin and Oxytocin; Tryptophan Metabolism and Neurodevelopment, placenta, fetal brain development, proliferation, differentiation, and neuronal migration, serotonin, oxytocin & bonding and stress buffering, TPH1 and TPH2, kynurenine pathwayX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

The Peptide Podcast
Neurohacking: Nootropics, Selank, and Semax

The Peptide Podcast

Play Episode Listen Later Apr 17, 2025 6:40


Today, we're talking about how nootropics and peptides like Semax (See-max) and Selank (SEH-lank) work together to support cognitive health, improve focus, and reduce mental fatigue. Let's start with nootropics. These are substances that are designed to support and enhance mental performance. Some work by improving memory, others help with focus, alertness, or reducing brain fog. Nootropics can be: Natural, like L-theanine or Lion's Mane Nutraceuticals, like Alpha-GPC or CDP-Choline, which support neurotransmitter production Or synthetic, like Modafinil or racetams “RASS-uh-tams”, which are often used off-label to promote wakefulness and focus Most nootropics work by affecting levels of key brain chemicals like dopamine, acetylcholine, or norepinephrine. They don't “make you smarter,” but they can improve how efficiently your brain is working—especially under stress or fatigue. Now, let's talk about peptides—specifically Selank and Semax, which are two of the most well-known nootropic peptides. Selank is more about calming and emotional regulation, while Semax leans into cognitive enhancement and brain performance. Think of Selank as the anti-anxiety sidekick and Semax as the mental sharpener. Selank works by boosting GABA activity, which helps calm the nervous system. That's why it's often used to reduce stress and anxiety without causing drowsiness or dependence — unlike traditional anti-anxiety meds. Interestingly, it also slightly increases BDNF, the brain growth factor that supports memory and learning. Semax, on the other hand, has a much stronger impact on BDNF. It's derived from ACTH, but it doesn't raise cortisol levels. Instead, it enhances BDNF, dopamine, and serotonin activity, making it great for improving focus, mental energy, and even mood. And that's what makes them such a powerful combo for some people. Selank helps create a calm, clear mental space — kind of like reducing background noise — while Semax boosts the brain's signal, improving neuroplasticity, motivation, and mental clarity. Together, they offer a full-spectrum brain support: emotional balance and cognitive performance. Whether you're dealing with brain fog, anxiety, or just want to perform at a higher level, these peptides could be worth exploring. Stacking Nootropics with Peptides One of the most popular strategies for cognitive support is to combine or stack peptides with nootropics. For example: Selank pairs well with L-theanine for calming, focused energy. L-theanine, an amino acid found primarily in green tea, promotes relaxation and reduces stress without causing drowsiness by increasing calming neurotransmitters like GABA and serotonin. Lion's Mane mushroom, a natural nootropic found in both wild and cultivated forms, can be stacked with Semax to naturally support memory, focus, and neurogenesis. Semax can be used with Alpha-GPC to support both short-term concentration and long-term brain health. Alpha-GPC (Alpha-glycerophosphocholine) is a choline-containing nutraceutical, often derived from soy or sunflower lecithin, that acts as a powerful nootropic. It increases levels of acetylcholine, a key neurotransmitter involved in learning, memory, focus, and muscle control. Because of its ability to cross the blood-brain barrier efficiently, Alpha-GPC is often used to enhance cognitive function, support brain health and neuroprotection, and improve physical performance by boosting power output and recovery in athletes. Semax can also be used with CDP-Choline for memory support, brain fog, and age-related cognitive decline. It too is a nutraceutical that provides choline, which the brain uses to produce acetylcholine, a neurotransmitter essential for memory, learning, and focus. It also delivers cytidine, which converts into uridine—a compound that supports neuron repair and brain cell membrane synthesis.  Alright, so one question we get a lot is, “What's the difference between CDP-Choline and Alpha-GPC?” It's a good one—because they're both great choline sources, but they work a little differently. Alpha-GPC delivers choline more directly, which means you'll feel that boost in focus and mental energy a bit faster. It's especially handy if you're doing high-intensity brain work or even something athletic. Lastly, I also want to dive into something a lot of people are curious about, Modafinil and racetams (RASS-uh-tams).  Modafinil (Provigil) is a prescription, stimulant medication used to treat sleep disorders (e.g., narcolepsy and obstructive sleep apnea) and shift work disorder. It's also used off-label as a focus-enhancing nootropic. It works by promoting wakefulness in the CNS. Researchers don't know exactly how it works, but it appears to affect areas in the brain that control attention and wakefulness. Racetams (e.g., Piracetam, Aniracetam, or Oxiracetam) are a class of compounds that enhance acetylcholine activity and neuroplasticity, leading to better learning, memory, and focus with subtle, non-stimulant effects.  While Modafinil provides a noticeable surge in alertness and productivity, racetams offer a more gradual cognitive boost that can be ideal for sustained mental performance. Just remember, peptides provide foundational support—helping your brain repair and function better long-term. Nootropics can then layer on immediate effects, like sharper focus or improved mood. Thanks for listening to The Peptide Podcast. If you found this episode helpful, please follow or leave a review. And if there's a topic you'd like to hear more about, feel free to reach out—we'd love to hear from you. As always, have a happy, healthy week! We're huge advocates of elevating your health game with nutrition, supplements, and vitamins. Whether it's a daily boost or targeted support, we trust and use Momentous products to supercharge our wellness journey.  Momentous only uses the highest-quality ingredients, and every single product is rigorously tested by independent third parties to ensure their products deliver on their promise to bring you the best supplements on the market.

Biohacking Superhuman Performance
#326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest

Biohacking Superhuman Performance

Play Episode Listen Later Apr 15, 2025 87:13


In this episode of the Longevity Podcast, I sit down with my good friend and brilliant supplement formulator, Kyal Van Der Leest, who's known for his innovative work in the peptide space. Together, Kyal and I explore the fascinating world of brain health and uncover powerful strategies to boost cognitive function.    What we discuss: Mold toxicity and health effects ... 00:03:49 Kyal's journey and Level Up Health ... 00:04:26 Lifestyle factors in brain health ... 00:19:19 Role of BDNF in neuroplasticity ... 00:24:44 Overview of neurotransmitters ... 00:30:12 Tessa Fensin and market withdrawal ... 00:39:01 Peptides for brain health ... 00:46:18 Blood flow and botanicals ... 00:53:06 Liposomal delivery benefits ... 01:06:22 Creatine for brain health ... 01:13:02 Kyal's supplement quality commitment ... 01:19:04 Conclusion and product info ... 01:26:00   Our Amazing Sponsors: Timeline: Mitopure is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10.   Wizard Sciences (Neural Rx) - isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. It supports mitochondrial efficiency, for more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

The Experience Miraclesâ„¢ Podcast
95. Blood Sugar Imbalance & Brain stress: The Neurological Connection w/ Dr. Jockers

The Experience Miraclesâ„¢ Podcast

Play Episode Listen Later Apr 15, 2025 49:43


Dr. Tony Ebel interviews Dr. David Jockers, a renowned expert in functional nutrition. Dr. Jockers shares in-depth insights about the critical connection between blood sugar stability and nervous system health, particularly in children. Drawing from his personal experiences and extensive clinical work, he explains how proper nutrition can transform brain function, behavior, and overall wellbeing. The conversation covers practical strategies for parents to implement, from protein prioritization to hydration tips, and explores how modeling healthy behaviors creates lasting change for children. This episode provides actionable nutrition advice that can truly move the needle for families dealing with chronic health challenges.[00:06:00] Blood Sugar StabilityDr. Jockers identifies blood sugar stability as a major "needle mover" for healthPersonal story of growing up with blood sugar crashesWhy seed oils are problematic for cellular health[00:12:00] Protein Priorities for ChildrenGuidance on protein intake and why protein should be consumed first in a mealHow protein intake stabilizes blood sugar and prevents crashes[00:16:00] The Neuroscience of Blood SugarConnection between nervous system stability and blood sugar stabilityThe difference between hyperglycemia and reactive hypoglycemia in childrenHow hypoglycemic episodes damage neurons and increase risk of neurodegeneration[00:21:00] POTS Syndrome and Blood Sugar ConnectionDiscussion of how blood sugar instability contributes to POTS syndromeThe cascade effect: blood sugar instability → nervous system instability → hormonal instabilityDr. Ebel's clinical observations with teenage and young adult patients[00:25:00] Optimizing Brain Function Through NutritionHow stable blood sugar increases BDNF (Brain-Derived Neurotrophic Factor)Benefits of BDNF: creativity, innovation, better connections between neuronsPractical meal structure and "eating the rainbow" for phytonutrients[00:30:00] Hydration and Supplementation StrategiesThe importance of hydration timing (away from meals)Electrolytes and minerals: benefits for kids, especially active onesSupplements vs. food: "90% of health results come from lifestyle"Key supplements that make a difference: Magnesium, Vitamin D, K2[00:36:00] Modeling Health for ChildrenThe importance of parents demonstrating healthy behaviorsTeaching children nutritional concepts through benefit-focused languageConnect with Dr. Jockers: Website: www.drjockers.comInstagram: @drjockersYoutube: @drdavidjockers-- DETAILS & REGISTRATION FOR THE FREE MAY AUTISM SUMMIT Follow us on Socials: Instagram: @pxdocs Facebook: Dr. Tony Ebel & The PX Docs Network Youtube: The PX Docs For more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care. Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click HereSubscribe, share, and stay tuned for more incredible episodes unpacking the power of Nervous System focused care for children!

The Liz Moody Podcast
9 Hidden Reasons You're Tired All The Time (+ Easy, Science-Backed Solutions)

The Liz Moody Podcast

Play Episode Listen Later Apr 14, 2025 32:39


Are you tired all the time? Energy is crucial to everything we do, from getting out of bed in the morning to getting work done throughout the day, and unfortunately it isn't as simple as just getting enough sleep. In this mini-episode, I'm giving you science-backed hacks you can use today to feel better tomorrow. As always, I don't recommend tackling all of these changes at once – instead, pick and choose a few changes that feel helpful to you, and build up from there. You deserve to feel present and reclaim your energy! 1:29 Meal Timing 3:36 Circadian Rhythm 6:27 Stress 9:14 Suppressing Emotions 13:14 Hydration 14:24 Movement 16:30 Busy, Not Productive 21:22 Task-Switching 23:51 Nagging To-Dos Ready to uplevel every part of your life? Order Liz's book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now!  To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome.  Check out these previous episodes of The Liz Moody Podcast mentioned in this episode: How To Work LESS AND Get MORE Done Top Attention Researcher: Our Attention Spans Are Down To 47 Seconds! Here's How To Fix It Neuroscience Hacks For Optimizing Dopamine, Serotonin, Oxytocin, BDNF, And More The Secret to Getting in Shape, Sleeping Better, Saving Money, And Being More Confident and Productive (Yes, Really!) with Dr. Katy Milkman New Circadian Science: Improve Your Energy, Metabolism, Focus, Strength, & More This episode is sponsored by: LMNT: go to DrinkLMNT.com/LizMoody to get a free LMNT sample pack with any order. Listen to Pulling The Thread with Elise Loehnen wherever you listen to podcasts, and check Elise out on Instagram @eliseloehnen. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast.  This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 320. Learn more about your ad choices. Visit megaphone.fm/adchoices

The MindHealth360 Show
75: Dr. Matt Bernstein: how improving metabolic health can radically transform our mental health

The MindHealth360 Show

Play Episode Listen Later Apr 4, 2025 85:13


In this fascinating interview, Dr. Matt Bernstein explains the groundbreaking and fast developing field of metabolic psychiatry, and outlines the ways diet, exercise, and other lifestyle factors can radically transform mental health outcomes. He explains why metabolic dysfunction is  common to all manifestations of poor mental health, and why metabolic intervention can have profound benefits to all mental health disorders. Dr. Matt Bernstein is Chief Medical Officer at EllenHorn Clinic, where he pursues alternative ways to help individuals achieve their best levels of functioning and happiness without relying solely on traditional psychiatric approaches, instead focussing on metabolism, nutrition, circadian-rhythm, biology, mind-body and exercise, He is also Chief Executive Officer at Accord, a residential clinic implementing metabolic psychiatry approaches to mental health, and is  one of the leading voices in the emerging field of metabolic psychiatry.  Dr. Bernstein received his medical degree from the Perelman School of Medicine at the University of Pennsylvania. He then trained at the MGH McLean Psychiatry Residency Program, where he served as chief resident and psychiatrist-in-charge, and later as assistant medical director of its schizophrenia and bipolar inpatient programme.  In this episode, learn why metabolism and mitochondrial health is at the core of our mental health, why merely reducing symptoms is not the desired outcome, and how Dr. Matt Bernstein helps his patients function at their best and happiest in everyday life. Discover why diet is the most powerful intervention, and why behavioural choices, such as exercise, mind-body practices and circadian-rhythm alignment, deepen healing by improving metabolism.    In this episode learn about: How Dr. Matt Bernstein discovered metabolic psychiatry and why it is so effective  in treating  mental health conditions, including psychosis, schizophrenia, bipolar disorder, depression, addictions, eating disorders, OCD, ADHD, and more. How metabolic psychiatry works without traditional psychiatric approaches, and why mainstream medicine often falls short in addressing the root-causes of mental health issues. Why the treatment goal is for patients to thrive in everyday life, rather than merely reducing symptoms. The link between metabolic dysfunction and mental health: how metabolic imbalances contribute to depression, anxiety, and treatment-resistant chronic disorders. How lifestyle interventions can reverse metabolic dysfunction: the role of ketogenic diets, exercise and circadian rhythms in improving metabolic and mental health. Key data and case studies that highlight the potential of metabolic psychiatry to transform mental health, and ways evidence is beginning to reveal that metabolic treatments outperform pharmaceuticals. How improving mitochondrial function boosts neurotransmitter function, BDNF, GABA-glutamate ratio, while reducing neuroinflammation and decreasing oxidative stress. Why mitochondrial health is fuelled by ketosis, and why good mitochondrial health profoundly improves our metabolism and mental health symptoms. Ways a ketogenic diet is a ‘miracle drug', and how it can cure treatment-resistant mental health disorders and reduce anxiety and depression. What a ‘clean' ketogenic diet looks like: the importance of high-quality whole foods and the targeted roles of fibre, proteins, cholesterol, and fats in optimising brain health. How to reach ketosis as a vegetarian or vegan, and practical guidance for those following plant-based diets. Root causes of poor mitochondrial health: how childhood trauma, toxins, pollutants, nutrient deficiencies, ultra-processed foods, sugar, and circadian rhythm dysregulation impact metabolism and mental health. An overview of Dr. Matt Bernstein's 4-week minimum residential programme Accord, and how the programme uses diet, mind-body practices and circadian rhythm alignment to improve metabolism as the main intervention for improved mental health. Why over testing and over supplementing can become part of the problem, and is avoided in the programme. How treatment strategies are tailored to the individual: why personalised interventions require ongoing support, why the process can be challenging, but why the effort can be incredibly rewarding.

Life Coaching for Women Physicians
259: Exercise and Energy - Energy For Optimal Health Series

Life Coaching for Women Physicians

Play Episode Listen Later Apr 3, 2025 17:05


SummaryIn this episode, of Metabolism, Muscles, and Mindset, Dr. Novitsky dives into one of her favorite topics as an obesity medicine doc and fitness enthusiast: the transformative link between exercise and energy. Listeners will gain insight into the bidirectional relationship between emotional and physical energy, the hormonal impacts of movement—including insulin sensitivity and cortisol regulation—and how exercise improves emotional regulation and stress resilience. She also touches on the importance of role models, confidence, and community, particularly for women, and how embodying strength becomes a purpose-driven, high-energy experience.She challenges the all-too-common belief that we're “too tired to exercise" and explores how breaking through that initial mental hurdle can unlock powerful benefits across physical, mental, and emotional energy systems.Exercise generates ATP, the body's basic energy currency, ramps up feel-good endorphins, and Brain-Derived Neurotrophic Factor (BDNF) - enhancing mood, cognition, and memory. Consistency in movement builds stamina and lowers the energy cost of exercise over time, making it easier and more enjoyable to stay active.Dr. Novitsky encourages everyone to find their “baseline minimum”—the small, sustainable commitment to movement that keeps energy and confidence high, without burnout.Key Points• Breaking the Mindset Barrier: Exercise can feel tiring before it's energizing—but getting started is the key to unlocking its benefits.• Energy on All Levels: Movement elevates physical, emotional, and mental energy by producing ATP, endorphins, and BDNF.• Stamina Through Consistency: The more conditioned you are, the less energy it takes to move—and the more mental energy you free up.• Sleep & Timing: Exercise can improve sleep quality, depending on timing and intensity. Emotional regulation through movement sets the stage for restful nights.• Hormone Harmony: Strength training boosts insulin sensitivity and regulates key hormones like cortisol, leptin, and ghrelin for steady energy.• Emotional Regulation: Exercise fosters better thoughts by creating a calm, grounded state—reducing spirals and buffering behaviors.• Confidence & Purpose: Strength training enhances confidence, especially for women, and becomes a powerful tool for embodying purpose.• The Power of Community: Supportive environments elevate both energy and belief in what our bodies can achieve.Timestamps• 00:02 – The exercise-energy paradox: feeling too tired to move• 01:35 – How ATP and endorphins fuel physical and emotional energy• 02:20 – Why morning workouts set the tone for your day• 03:30 – BDNF and mental clarity: your brain's “topsoil”• 04:45 – The interconnected nature of physical, emotional, and mental energy• 06:00 – Exercise timing and its effect on sleep and emotional regulation• 07:11 – Bringing a “vacation mindset” to everyday life• 08:10 – Building stamina: why conditioning makes movement easier• 09:30 – Mental energy saved through physical conditioning• 10:45 – Emotional regulation through movement: less stress, better thoughts• 11:50 – Exercise, insulin sensitivity, and avoiding post-meal energy crashes• 13:30 – Hormonal impacts: cortisol, leptin, and ghrelin• 14:15 – Strength as confidence: how exercise becomes empowerment• 15:45 – Role models and community: elevating female strength• 16:30 – Finding your baseline minimum: the smallest step for maximum energyFollow Dr. Ali Novitsky on Socials⁠⁠TikTok⁠⁠• ⁠⁠Facebook⁠⁠• ⁠⁠Instagram⁠⁠• ⁠⁠YouTube⁠Work with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠Enroll TODAY⁠⁠• Transform® 9.0 – Enrollment now open! Starts May 5th. ⁠⁠Learn more HERE⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠Enroll HERE⁠⁠• Nutrition Training Program (48-CME) is enrolling now! Get the details ⁠⁠HERE⁠⁠.• The Fit Collective® x InBody USA/Canada – Get 15% off select models. ⁠⁠Click HERE⁠

The Peptide Podcast
Peptide Stacking

The Peptide Podcast

Play Episode Listen Later Apr 3, 2025 6:12


Today, we're talking about a hot topic in the world of fitness and wellness: peptide stacking. Whether you're looking to build lean muscle, burn fat, enhance recovery, or boost cognitive function, peptide stacking could be a game-changer. But, just like anything, it's important to know the ins and outs of how it works and how to “stack” safely. What is Peptide Stacking? So, what is peptide stacking, and how can it benefit you? Let's break it down. At its core, peptide stacking refers to the practice of combining different peptides to maximize their individual effects and synergize their benefits. Keep in mind, there's no "magic" stack that works for everyone. Each stack is chosen based on the person's symptoms or what effect they want to achieve. The concept is pretty similar to stacking supplements or combining different types of training programs. When done right, stacking peptides can enhance muscle growth, accelerate fat loss, improve recovery, and boost cognitive function. But, not all peptides play well together, and some shouldn't be mixed. We'll dive into those potential issues in a bit. First, let's talk about the benefits of stacking. What Are the Potential Benefits of Stacking Peptides? So, what are the benefits of stacking peptides? First off, synergistic effects – when peptides work together, they can boost each other's impact, helping with muscle growth and speeding up recovery time. Then, there's the ability to tackle multiple goals at once. Whether you're focusing on fat loss, building muscle, or even improving brain function, stacking peptides lets you work on a few things at the same time. Lastly, customization is a big perk. You can adjust your stack based on your specific needs and make changes as your body adapts, so you're always on track to reach your goals.   What Are Some Risks of Peptide Stacking? Some peptides shouldn't be mixed, as they can cause negative effects or reduce each other's effectiveness. For example, combining GHRP-6 (stimulates growth hormone) with somatostatin (inhibits growth hormone) would be counterproductive. Also, stacking too many peptides affecting the same pathways could overwhelm your system, leading to side effects like insulin resistance or excessive GH levels.  Popular Peptide Stacks While there are countless peptide therapies and hundreds of possible stack combinations that can offer great benefits, I can't cover them all, but let's dive into some of the most common and effective peptide stacks for different goals. Building Lean Muscle Mass: If you're aiming to pack on lean muscle, a great stack to try is CJC-1295 with DAC + Ipamorelin + BPC-157. This combo helps release growth hormone and boosts muscle recovery. But if you really want to take it up a notch, adding MK-677 to the mix is a game-changer. MK-677 is a growth hormone secretagogue that mimics ghrelin, the hunger hormone, which not only increases growth hormone levels but also helps with muscle growth and fat loss. One of the best things about MK-677 is its ability to stimulate appetite, which is perfect for anyone who's training hard but struggles to eat enough calories and protein. If you have a naturally low appetite, MK-677 can make it much easier to consume the fuel you need for muscle growth and recovery. Fat Loss: For fat loss, MOTS-c + Semaglutide is a great stack. MOTS-c helps with fat metabolism, and Semaglutide helps control appetite, making it easier to stick to a calorie-restricted diet for sustainable fat loss. Another effective stack is CJC-1295 + Ipamorelin + Semaglutide. The CJC-1295 and Ipamorelin combo promotes growth hormone release, which supports fat burning and muscle preservation, while Semaglutide helps control hunger, making fat loss a little easier. If belly fat is a particular concern, consider Tesamorelin + Semaglutide. Tesamorelin boosts growth hormone, especially around the abdominal area, reducing visceral fat (that deep belly fat). This stack is great for targeting stubborn belly fat while still promoting overall fat loss. Recovery & Healing: When it comes to recovery, BPC-157 + TB-500 is an incredible combo. BPC-157 is known as the king of healing peptides. It helps speed up tissue repair, reduce inflammation, and regenerate muscles, ligaments, and tendons. TB-500 works alongside it to promote wound healing and cell regeneration, further reducing inflammation and speeding up recovery from injuries. Together, these peptides help you heal faster and get back to your workouts with less downtime. Cognitive Function: If you're looking to boost your brainpower, Cerebrolysin + Semax is a solid stack. Cerebrolysin enhances brain function by promoting neuroplasticity and stimulating growth factors to protect and regenerate brain cells, improving memory and mental clarity. On the other hand, Semax enhances memory, reduces stress, and improves focus by increasing BDNF (brain-derived neurotrophic factor). A great approach is to use Semax daily for consistent cognitive benefits and Cerebrolysin on alternate days for neuroprotection and brain regeneration. This way, you're supporting your brain health and mental performance consistently. Peptide stacking can be an incredibly powerful tool when used correctly, helping you achieve your fitness, recovery, and cognitive goals faster and more efficiently. However, it's vital to understand the potential risks and make sure you're combining peptides that complement each other rather than counteracting each other's effects. Always be mindful of the peptides you're stacking. Thanks for listening to The Peptide Podcast. If you found this episode helpful, be sure to subscribe and leave a review. And as always, have a happy, healthy week.   We're huge advocates of elevating your health game with nutrition, supplements, and vitamins. Whether it's a daily boost or targeted support, we trust and use Momentous products to supercharge our wellness journey.  Momentous only uses the highest-quality ingredients, and every single product is rigorously tested by independent third parties to ensure their products deliver on their promise to bring you the best supplements on the market.

the goodDEMAND podcast
Seamus Sullivan: Longevity, Health and Fitness #36

the goodDEMAND podcast

Play Episode Listen Later Apr 2, 2025 58:09


On this episode of the GOODDEMAND podcast, we sit down with a longevity expert and performance health coach to break down the real science behind living longer, stronger, and healthier—without the gimmicks.We talk about the difference between health, fitness, and longevity, and why optimizing for one can sometimes compromise the others. We explore core strategies like diet, sleep, muscle mass, VO2 max, mental health, and social connection, plus cutting-edge topics like plasma exchange therapy, blue zones, red light, biohacking, and Brian Johnson's blueprint lifestyle.This conversation is perfect for anyone curious about personal development, biohacking, anti-aging, or just wanting to live better. No fluff—just actionable science and expert coaching insights.Questions Answered in This Episode:- What's the difference between fitness, health, and longevity?- Does muscle mass actually make you live longer?- What diet is best for anti-aging and long-term performance?- How does VO2 max predict your healthspan and lifespan?- Can red light, sleep tracking, or blue light blocking really work?- What's the deal with plasma exchange therapy and Brian Johnson's longevity protocol?- How do you stay consistent with protein intake and workouts?- Why are social connection and purpose vital for your health?Timestamps:00:00 – Intro + What really defines longevity vs. health vs. fitness04:15 – Is 80% of lifespan lifestyle-based?07:10 – Muscle mass, bone health & falling risk in aging10:00 – VO2 max, healthspan, and performance synergy13:40 – Diet for longevity: Blue zones, protein, fasting & real-world application21:00 – Plant-based vs. high-protein: What works best and why28:20 – How to consistently hit your protein targets33:00 – The dangers of going "all-in" on bulking or shredding36:40 – The problem with over-optimizing gut health41:00 – Peter Attia's cardio protocol and the role of VO2 max46:00 – HIIT vs. Zone 2: Which is better for busy professionals?51:30 – Brain health, BDNF & why movement boosts cognition55:00 – Sleep: Why it's the most underrated biohack58:20 – Shift workers, circadian rhythms & practical sleep solutions1:03:00 – Brian Johnson: Longevity pioneer or outlier?1:08:10 – Plasma exchange therapy & blood transfusions explained1:12:00 – Lifestyle medicine: Science vs. spirituality & being human1:16:40 – Food deserts, systemic inequality & wellness access1:21:30 – Building community, purpose, and mindset for a longer life1:26:00 – Final takeaways: Why you're one decision away from changeResources Mentioned:- Podcast Guest: Seamus Matthew Sullivan- Synogenics (Longevity Clinic): https://www.synogenics.com- Seamus' Coaching Program: DM Seamus on Instagram for coaching- The Macro Perspective Podcast: Available on all platformsSubscribe now for more episodes on longevity, fitness, self-development, and modern health optimization.Like, comment, and share with someone who needs to hear this.Follow us on InstagramFollow Us on YouTube

Intelligent Medicine
Leyla Weighs In on Unlocking Longevity: Tips for Living Beyond 100

Intelligent Medicine

Play Episode Listen Later Mar 28, 2025 24:24


Biohacking for Longevity: Extending Your Health Span. In this episode of "Leyla Weighs In," registered dietician and nutritionist Leyla Muedin discusses the concept of biohacking and its potential to extend lifespan and health span. Leyla explores various biohacking strategies such as diet optimization, regular physical activity, stress management, enhancing sleep quality, and maintaining strong social connections. She emphasizes the importance of epigenetics, targeted lifestyle changes, and advanced medical interventions like stem cell therapy. You will learn practical biohacking tips, including the benefits of intermittent fasting, the significance of exercise, and how to use wearable technology for health tracking. Leyla also highlights the role of supplements and personalized nutrition in promoting longevity, alongside maintaining good dental health and a sense of purpose. Through these combined efforts, Leyla aims to inspire listeners to not only live longer lives but to enjoy better health and vitality.

Breast Implant Illness
Episode 110: The Power of Diet and Exercise on Brain Function with Dr. Monisha Bhanote

Breast Implant Illness

Play Episode Listen Later Mar 27, 2025 38:06


Neuroplasticity, the brain's ability to reorganize itself by forming new neural connections, is more powerful than many realize. In our latest episode, Dr. Manisha Bhanote delves into how lifestyle choices can bolster this process. Did you know that activities like regular physical exercise and a diet rich in omega-3 fatty acids can significantly boost brain-derived neurotrophic factor (BDNF)? BDNF is crucial for cognitive function and mental health. By making informed dietary choices, we can remarkably influence our brain health. Connect with Dr. Bhanote Website (https://www.drbhanote.com/) Show Highlights: Self-Care and Cellular Health (00:01:13) Importance of self-care and its connection to cellular health and well-being The Importance of Sleep (00:03:35) Sleep's crucial role in health Gut-Brain Axis and BDNF (00:04:55) Dr. Bhanote explains the gut-brain axis and its influence on brain-derived neurotrophic factor (BDNF) levels. Habits vs. Rituals (00:08:23) Moving from habits to rituals for better self-awareness and intentional living Fermented Foods and Probiotics (00:14:33) The importance of incorporating fermented foods into the diet for gut health Detoxification Practices (00:21:44) Suggestions for practices like movement and saunas to help remove toxins from the body Role of Diet in Health (00:23:04) Importance of whole foods in combating chronic diseases and mental health issues Self-Care and Parenting (00:27:49) Discussion on how parental habits influence children's dietary choices and health Connect with Dr. Monisha Bhanote Website (https://www.drbhanote.com/) Facebook (https://www.facebook.com/drbhanote/) Instagram (https://www.instagram.com/drbhanote/) YouTube (https://www.youtube.com/@drbhanote) Pinterest (https://www.pinterest.com/drbhanote/) Let's Connect Podcast: https://podcasts.apple.com/gb/podcast/breast-implant-illness/id1678143554 Spotify: https://open.spotify.com/show/1SPDripbluZKYsC0rwrBdb?si=23ea2cd9f6734667 TikTok: https://www.tiktok.com/@drrobertwhitfield?t=8oQyjO25X5i&r=1 IG: https://www.instagram.com/breastimplantillnessexpert/ FB: https://www.facebook.com/DrRobertWhitfield Linkedin: https://www.linkedin.com/in/dr-robert-whitfield-md-50775b10/ X: https://x.com/rob_whitfieldmd Read this article - https://www.breastcancer.org/treatment/surgery/breast-reconstruction/types/implant-reconstruction/illness/breast-implant-illness Shop: https://drrobssolutions.com SHARP: https://www.harp.health NVISN Labs - https://nvisnlabs.com/ Get access to Dr. Rob's Favorite Products below: Danger Coffee - Use our link for mold free coffee - https://dangercoffee.com/pages/mold-free-coffee?ref=ztvhyjg JASPR Air Purifier - Use code DRROB for the Jaspr Air Purifier - https://jaspr.co/ Echo Water - Get high quality water with our code DRROB10 - https://echowater.com/ BallancerPro - Use code DRROBVIP for the world's leader in lymphatic drainage technology - https://ballancerpro.com Ultrahuman - Use code WHITFIELD10 for the most accurate wearable - https://www.ultrahuman.com/ring/buy/us/?affiliateCode=drwhitfield

Dr. Joseph Mercola - Take Control of Your Health
Butyrate: Your Gut's Secret Weapon for a Healthy Brain

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Mar 24, 2025 11:13


Story at-a-glance Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection

Janett Arceo y La Mujer Actual
Dr. Eduardo Calixto… La plasticidad neuronal que genera la proteína: BDNF.

Janett Arceo y La Mujer Actual

Play Episode Listen Later Mar 22, 2025 82:57


-Dr. Eduardo Calixto… La plasticidad neuronal que genera la proteína: BDNF.-Dr. Jorge Antonio Torres Martínez…Insuficiencia Venosa Crónica y Microangiopatia Diabética… ¿Qué relación guardan ambas enfermedades?- Gaby Pérez Islas… El duelo por los desaparecidos.-María Filippini. Actriz, cantante y bailarina… Reconocimiento a su trayectoria en el Teatro Silvia Pinal // Obra: La Chica del Bikini Azul.  

The Low Carb Hustle Podcast
287: Fasting for Mental Domination: The Cheat Code for Focus, Willpower, and Peak Performance

The Low Carb Hustle Podcast

Play Episode Listen Later Mar 17, 2025 15:13


Want to sharpen your focus, build unbreakable discipline, and tap into peak mental performance?  In this episode, we break down how fasting rewires your brain for productivity, boosts BDNF for sharper thinking, and trains your willpower like a Navy SEAL. Hear how Jack Dorsey, Georges St-Pierre, and monks use fasting to gain an edge—and learn how you can do the same. Plus, get a simple fasting protocol to unlock mental clarity and self-control starting today!

The Keto Kamp Podcast With Ben Azadi
#962 Doctors Won't Tell You This! - What Happens When You Stop Eating For 36 Hours with Ben Azadi

The Keto Kamp Podcast With Ben Azadi

Play Episode Listen Later Mar 12, 2025 21:28


In this episode of the Metabolic Freedom Podcast, we dive deep into the science of fasting and what happens inside your body during a 36-hour fast. From lowering insulin and tapping into fat-burning mode, to activating autophagy (cellular cleanup) and boosting brain-derived neurotrophic factor (BDNF), this fasting timeline unlocks powerful metabolic benefits. We explore: ✅ The first 14 hours: Lower insulin, burn glycogen, and experience energy diversion. ✅ 16-hour mark: Autophagy kicks in, clearing out damaged cells and enhancing fat burning. ✅ 24-hour mark: Digestive system reset with an intestinal stem cell reboot. ✅ 30-hour mark: BDNF production surges, improving brain function and mental clarity. ✅ 36-hour mark: Significant fat loss, increased ketone production, and a metabolic reset. Ben answers common fasting questions, including muscle loss concerns, what to drink, exercise during fasting, and the best way to break a 36-hour fast. Plus, hear about the longest fast ever recorded!

Elev8 Your Life
#184-Understanding Brain Health: The Mind-Gut Connection

Elev8 Your Life

Play Episode Listen Later Mar 12, 2025 40:30


Exploring the mind-gut connection reveals that gut health significantly impacts brain function, mood, and cognitive disorders. Key factors include sleep, hydration, exercise, essential nutrients like DHA and selenium, and the role of cholesterol in maintaining brain health. Regular exercise boosts BDNF, promoting neuron growth and cognitive resilience.Get the notes for this podcast by joining our email list at Elev8YourLife.comDirections to join The Elev8 Tribe:1. Click the Link: Visit https://web.facebook.com/groups/10334779467352422. Join Group: Click the “Join Group” button.3. Answer Questions: Respond to any questions or agree to the group rules.4. Wait for Approval: An admin will approve your request, and you'll receive a notification once you're in.

The Exam Room by the Physicians Committee
Why Weight Loss Makes the Brain Happy | Dr. Hana Kahleova

The Exam Room by the Physicians Committee

Play Episode Listen Later Mar 11, 2025 30:48


The brain undergoes a major change during weight loss. The result often is a much happier person with less depression. But the reason why this is happening goes far beyond just enjoying a smaller waist and what you see in the mirror.   There are substantial chemical changes occurring in the brain that alleviate depression, improve mood, and bolster mental health.   Dr. Hana Kahleova explores the science behind the brain boosting benefits of weight loss when she joins Chuck Carroll on The Exam Room Podcast.   — In This Interview —   - Bi-directional relationship between obesity and depression. - High-carb diets more beneficial than keto diets for mental health. - Fat quality, carbohydrates, fiber, and flavonoids are important. - BDNF (brain-derived neurotrophic factor) plays a crucial role in mood regulation.  — — SHOW LINKS — — Watch - Weight Loss and the Brainhttps://www.youtube.com/watch?v=1RBUCWA2IJI — — EVENTS — — Lotus Health Summit Where: Rochester, MN (DATES) When: April 17-18, 2025 Who: Dr. Neal Barnard, Brenda Davis, Chuck Carroll Tickets: https://www.lotushealthfoundation.org/2025-symposium-and-gala — — BECOME AN EXAM ROOM VIP — — https://www.pcrm.org/examroomvip — — THIS IS US — — The Exam Room Podcast Instagram: https://www.instagram.com/theexamroompodcast — — — Chuck Carroll Instagram: https://www.instagram.com/ChuckCarrollWLC Facebook: http://wghtloss.cc/ChuckFacebook X: https://www.twitter.com/ChuckCarrollWLC — — — Physicians Committee Instagram: https://www.instagram.com/physicianscommittee Facebook: https://www.facebook.com/PCRM.org X: https://www.twitter.com/pcrm YouTube: https://www.youtube.com/user/PCRM Jobs: https://www.pcrm.org/careers — — SUBSCRIBE & SHARE — — 5-Star Success: Share Your Story Apple: https://apple.co/2JXBkpy​​ Spotify: https://spoti.fi/2pMLoY3 Please subscribe and give the show a 5-star rating on Apple Podcasts, Spotify, or many other podcast providers. Don't forget to share it with a friend for inspiration!  

#DoorGrowShow - Property Management Growth
DGS 285: The Nervous System and its Powerful Role in Business Performance

#DoorGrowShow - Property Management Growth

Play Episode Listen Later Mar 6, 2025 33:42


After working with property management business owners for over a decade, I've realized that the problems they are experiencing tend to be deeper than issues in the business… In this episode of the #DoorGrowShow, property management growth expert Jason Hull sits down with Sam Womack to discuss entrepreneurship, health, and how the two intertwine. You'll Learn [01:57] How stress affects your health [13:48] The impact of oxygen and proper relaxation [17:40] The importance of being able to calm your nervous system [26:10] More health expert insights   Tweetables “Everybody's doing the best they can with their current limited access to knowledge and resources.” “Don't beat yourself up for when you feel stressed out. Just make sure that before you continue that stress rollercoaster, like find some space to find some peace.” “You don't have to like beat all your competitors in a lot of instances, you just need to outlive them. You just need to outlast them.” “High performance isn't just how hard you push. It's about how well you recover and regulate.” Resources DoorGrow and Scale Mastermind DoorGrow Academy DoorGrow on YouTube DoorGrowClub DoorGrowLive TalkRoute Referral Link Transcript [00:00:00] Sam: If you don't find time to balance your nervous system or don't work on implementing tools to balance your nervous system, then you are limiting yourself to lower performance in the short term and decreasing performance in the long term.  [00:00:15] Jason: Welcome DoorGrow property managers to the Property Management Growth Show. If you are a property management entrepreneur that wants to add doors, make a difference, increase revenue, help others, impact lives, and you're interested in growing in business and life, and you're open to doing things a bit differently, then you are a DoorGrow property manager. [00:00:37] Jason: So DoorGrow property managers love the opportunities, daily variety, unique challenges, and freedom that property management brings. Many in real estate think you're crazy for doing it. You think they're crazy for not because you realize that property management is the ultimate high trust gateway to real estate deals, relationships, and residual income. At DoorGrow, we are on a mission to transform property management business owners and their businesses. We want to transform the industry, eliminate the BS, build awareness, change perception, expand the market, and help the best property management entrepreneurs win. I'm your host, property management growth expert, Jason Hull, the founder and CEO of DoorGrow. [00:01:21] Jason: Now let's get into the show. Cool.  [00:01:24] Jason: And I'm hanging out here with sam Womack. Sam, welcome to the show.  [00:01:29] Sam: Thanks for having me on. I'm excited to be here.  [00:01:31] Jason: Cool. So Sam we met at a local mastermind here in the Austin area, which is really cool. And for those that know that I run a mastermind for property managers, I also eat my own dog food and believe in getting coaching and learning and growth and everything else. [00:01:52] Jason: And wanted to connect with some people locally and make some friends as well. So, Sam's one of those friends. So, Sam, welcome to the show. And why don't you give people a little bit of background on yourself and what you do and how you kind of. Got into running businesses and doing cool stuff. [00:02:10] Sam: Yeah, no, thank you. First off, I don't do anything near as difficult as you guys. Managing property and tenants, I think is a feat to be held. And so props to all you guys out there crushing it in real estate. I cut my teeth in entrepreneurship starting at a young age. I was charging like 30 bucks an hour to teach old people how to use their computers, you know, tell their life story. [00:02:29] Sam: They'd pay me 30 bucks an hour while they sat there and henpecked. It was pretty ingenious. Fast forward into later on in life when the pandemic hit the business that I was launching just disappeared overnight. The retail died, everything that I've been working on, all the investors pulled out. [00:02:44] Sam: I was left with a few grand in my name and a baby on the way, living in a studio apartment with my wife. Had to figure something out, went into supply distribution, and a couple years later, fast forward, I did about 20 million in revenue as a solopreneur distributing gloves, masks, COVID test kits, etc. [00:03:01] Sam: But throughout that time, I dealt with like a really serious health issue. Stress had kind of overwhelmed me and I ended up with an autoimmune condition in my brain and through the journey of healing that autoimmune condition that was presenting as like early onset Alzheimer's, it was kind of a mystery. [00:03:16] Sam: They didn't know what was happening. I developed a deep passion for finding the root of health and the root of optimization and root of performance. A lot of that came through working with my mom, who's a preeminent physician focusing on anti aging and regenerative science here in Austin. [00:03:31] Sam: And so I typed her handwritten notes for a couple years and followed the patient journeys of the elite because she has a concierge practice for the elite here in Austin. And as I saw what drove change in their lives, I learned a lot about the human psyche and I learned a lot about how each of our individual unique biologies are very different when it comes to what we choose to do to find optimization or find optimal health. And so now I have a passion for bringing that to the masses. And as the pandemic waned, and as I healed, I became passionate about different physics based modalities and the different systems in the body and how to reach optimal performance. [00:04:07] Sam: And now I have a wellness center here in Austin that focuses on performance optimization, as well as maximizing human potential and transitioning the human experience as well as a research Institute called Human Beaming Research Institute, where we present the stories of the truth about health and where we help bring true health science to light so that people understand what's actually true, not truth that's manufactured by special interests, but truth that's founded in science. [00:04:36] Jason: Got it. Yeah. I mean, there's kind of a battle right now, right? We're like seeing it all play out live real time. Oh yeah. Got this whole make America healthy movement. We've got RFK, Bobby like and it seems like there's some major disruptions that are kind of happening right now and there's a battle and we're waking up. [00:04:58] Jason: A lot of people are waking up that hey, you know, big food, big pharma, you know, big government are not in favor of us being healthy for some reason, which is kind of scary. So yes, yeah kind of waking up to this and I don't know, maybe we're all biohackers now. I don't know.  [00:05:17] Sam: Yeah. No, I you're absolutely right I think that humanity as a whole is kind of done drinking the Kool Aid when it comes to what we've been told is the truth. [00:05:27] Sam: And, you know — [00:05:29] Jason: Yeah. Cause the Kool Aid has like glyphosate in it and like, also like molds and mycotoxins, like it's got bad stuff all over it. And I'm not saying actual Kool Aid. This is metaphorical people. Metaphorically.  [00:05:42] Sam: Yes. And when you look at like where, you know, just briefly to when you follow the money and you see that, like, from a business standpoint, one of the largest mergers and acquisitions in history, if you bring it to current dollar value was when big tobacco bought the food industry and you look at when that transition happened and you see what happened to our food supply and you know, we're fish in a barrel that they're just taking their pick of right now when it comes to what we have that's societally acceptable to put in our bodies and societally acceptable to engage in, in terms of social interaction, et cetera. [00:06:15] Sam: And it, yeah. Kind of funnels us down this path of high stress, which kind of takes us to today's topic with the nervous system. But yeah, I don't don't know if you have anything else you want to discuss before we dive in.  [00:06:25] Jason: Well, I want to point out. So Sam really sharp guy, as you can tell already, Sam's going to be a speaker at our DoorGrow Live conference. [00:06:35] Jason: And he's going to talk about some really cool stuff that we're very holistic at DoorGrow. And so I know that in coaching entrepreneurs and having talked to thousands of property management business owners and coaching hundreds of clients that it's never really the business or that they're spending too little time in their business that's keeping them from succeeding in business. It's everything else, especially health, especially their relationships, especially their marriage. Like these things create a lot of friction for entrepreneurs And they've got a lot going on. You're not really talking about property management when you come to DoorGrow Live, but I do believe it will be a game changer for them to be able to perform more, be able to get more out of their business, be able to get more out of life, which is the goal of having a business, right? [00:07:20] Jason: That's more freedom and more fulfillment. So, yeah. So if you have not yet gone to doorgrowlive.Com and gotten your tickets. Go do that right now. Go get your tickets and make sure you're at that event. Come hang out with us in North Austin at round rock at the Kalahari resort. It's going to be awesome. [00:07:36] Jason: All right. Shameless plug completed. Now, Sam, let's get into talking about the topic at hand.  [00:07:43] Sam: Yeah, I know. And thank you. And I'm really excited to get on stage and speak and I'm going to save some nuggets for the stage. Won't give it all the way here. So I'm really excited about that and helping you guys understand what the true root of your full potential actually is and not from some woo woo space, but actually understanding like the fundamental simple science beneath high performance and beneath fulfillment in life because it really does break down to a very simple equation. One of the key factors is a molecule, and that molecule is actually oxygen. [00:08:13] Sam: And when your brain is in a high stress state you would think that your body would give it more oxygen under high stress, right? But under high stress, you actually have vasoconstriction. Your blood pressure rises, blood gets pumped to your extremities, you got to get away from that proverbial bear, right? [00:08:29] Sam: But for y'all, that bear is the constant wave of tenant complaints, the constant wave of, you know, economic factors interest rate shifting stuff like that And so you have this like constant bear chasing you and if you're always in that state of fight or flight your brain is patterned to operate on survival mechanisms and a lower amount of oxygen and so And then we get this like male, sometimes male and female, but we get this, like this almost masculine energy of like, let's go conquer and do this high stress, high action push, push, push coffee, stimulant. [00:09:03] Sam: And we're really performing with our hands tied behind our back at that point, because our brain has less oxygen in it. And when you look at the other side of the nervous system, which is our parasympathetic nervous system you have this increase of oxygen in the brain. which actually raises serotonin instead of relying on that dopamine cortisol roller coaster, right? [00:09:24] Sam: And so, at the base of this is oxygen, which is bringing us life, which is creating ATP, cellular energy. And, to put it simply, If you don't find time to balance your nervous system or don't work on implementing tools to balance your nervous system, then you are limiting yourself to lower performance in the short term and decreasing performance in the long term. [00:09:48] Sam: Higher relying on stimulants, higher amounts of of just stress and cortisol and dopamine reliance in the long term, which takes away from your ability to connect with others, to find community, to find that real fulfillment that comes in life.  [00:10:02] Jason: And so what you're saying is we shouldn't just overdose on coffee that here in the U. S. probably has mold in it and makes you not feel good and have to pee way too much. And then not, you know, take care of ourselves in breathing effectively and getting too little sleep, too much hustle, too much stress.  [00:10:23] Sam: Yeah.  [00:10:24] Jason: Okay.  [00:10:24] Sam: Yeah, we can get addicted to that pattern because stress actually can feel really good. [00:10:30] Sam: When you have dopamine augmenting that cortisol, right? Without dopamine, cortisol feels really crappy. You know, you look at high anxiety. You look at that restlessness feeling where you don't feel good. You're on edge. That's when your cortisol's high and your dopamine is kind of low because you've been exhausting the dopamine stores by just pushing it. [00:10:50] Sam: Dopamine is supposed to be a short term reward to get us out of the stress back into a parasympathetic state. Dopamine was never meant to be the consistent ongoing reward. Because, like, think about it for survival, right? If you're, you know, trying to get away from the bear, and you're running, that needs to somewhat feel good, in order to get you through that stress. [00:11:11] Sam: So dopamine kicks in when oxygen lowers in the brain. And then, when you get out of the stress, you find that parasympathetic state again, you calm down, oxygen rises in the brain, serotonin rises, which is that more deeper, long term fulfilling chemical, that actually leads to creativity as well. But our society tells us that love is dopamine. It tells us that success is dopamine. It tells us achievement is dopamine. It gives us these dopamine triggers for all of the cultural hierarchy and the cultural validation, that external validation when you do something to succeed and you show it off, that's a dopamine trigger. Social media is a trigger. So all of these things, society is structured in a way that says, "dopamine's the reward. Now go buy shit, right?" Like almost all the financial economy is driven surrounding dopamine, which is a ultimate losing game because you guys all know that it doesn't really provide that end fulfillment, but since it feels good, we're kind of stuck in that loop. And so. What I want to help illuminate is where true fulfillment can be found and help with some kind of practical tools and a practical understanding of this foundational science so that when you're looking to perform at your best, you can give yourself a break and allow yourself to relax. [00:12:22] Sam: You know, before you have that next cup of coffee to keep yourself going, take some deep breaths, find some space to relax. Don't worry that your brain doesn't feel a hundred percent on. And give yourself some space to allow that peace in knowing that you're raising oxygen in the brain. You're opening oxygenation to areas that are going to drive creativity, that are going to allow for connection, that are going to allow for more presence in your body. [00:12:44] Sam: You'll be a different person in the home. You'll be a different person towards yourself. And so these are critical components of understanding the power of the nervous system when it relates to performance. Because high performance isn't just how hard you push. It's about how well you recover and regulate, and it's about how you create that balance that pushes for longevity and pushes for long term endurance and strength. [00:13:09] Sam: Because if you want to succeed and grow your business 5x, 10x, 100x, you need endurance. Sympathetic, nervous system tone, high stress does not create endurance. It's short term bursts, you crash out or you keep hitting the stimulants. And it keeps you in this narrow window of potential. You find that parasympathetic, you find that relaxation, you get creativity going in your brain, you get higher oxygenation in your brain, you're shifting gene expression towards longevity. [00:13:33] Sam: So it's a pretty powerful tool. And most people think, "oh, I don't want to meditate, you know, or I don't want to relax", or they don't feel safe when they're calm. And it's something to just work on shifting your perspective on because there's true power in that state of peace.  [00:13:48] Jason: A while back, I read this book. [00:13:50] Jason: I don't know if you heard of this. It's called the Oxygen Advantage. It's by a guy named Patrick Mckeown and it's got a forward by Dr. Joseph Mercola, but it's interesting because basically the book is about how he trains athletes to breathe through their nose while working out instead of their mouth, which like exercises the lungs and increases lung capacity. [00:14:15] Jason: But if they're, if we're constantly operating with our mouth open and working with our mouth open, we actually decrease our lung capacity. And so, athletes are just burning out really quickly and they don't have the ability or the capacity to, you know, absorb as much oxygen. So like working out those muscles, like breathing through your nose, you know, is something that talks about, but that's interesting that when we're not calm, we're not getting enough oxygen that we're not recovering, we're not regulating our stress, our body probably starts to eat itself a little bit and, you know, and then we get addicted to dopamine and you know, in business, most businesses fail and really you don't have to like beat all your competitors in a lot of instances, you just need to outlive them. You just need to outlast them. And that, that endurance aspect. And so I think, you know, I think we're going to go through some financial turmoil in the marketplace. Things are probably going to get worse before it gets better as we're cleaning up all this mess financially that is going on in the government. [00:15:18] Jason: And the U S dollar is like, I think it's been going down from its original value down and down as they've been stripping value out of it through inflation and giving that money to who knows who. And so. I think there's going to be a big transition. It's going to get really stressful. [00:15:33] Jason: And I think the businesses that are just able to last through this transition and endure and they're focused on the long game are the ones that are going to win.  [00:15:43] Sam: Absolutely.  [00:15:44] Jason: And there's going to be a lot just eaten up.  [00:15:46] Sam: Yeah. And if you don't allow that perspective of what you just explained about business to apply to your own self and your health, you know, what got you here won't get you there. [00:15:54] Sam: And if you want to sustain and succeed through the turmoil, then you need to adapt. And when you have a high stress state, you actually lose BDNF expression in the brain brain neurotropic factor and brain derived neurotropic factor. And that is our adaptability aspect and factor in our brain. And it literally decreases its efficiency, the higher, the more chronically stressed we are. [00:16:18] Sam: And so it's super important. You guys can look up BDNF and understand its role with oxygenation in the brain. And so fundamentally, you know, the more oxygenated your brain is, the greater your access to intuition, memory, and high level thinking. And those are key components to succeeding in business. [00:16:33] Sam: And when you are in a state of constant survival mode, constant reactivity, constant push, hustle, you lose that space to develop creative longterm solutions. You lose that space to be able to get that spark of inspiration on how to pivot around the corner and see around that corner or do something a little differently than what other people are doing. [00:16:55] Sam: And that's why even you look at like Thomas Edison, Benjamin Franklin, like they would love to access that like state estate, the theta state just akin to sleep. They would put like a lead ball in their hand over a metal plate. And then as they were falling asleep. It would drop and the ball would hit the metal plate wake them up and they'd have their pen and their quill and ink on the table with a candle and then they'd have their formula or problems they were trying to solve and then they'd go to solving it because that was deep parasympathetic state where that creativity was opened up brain oxygenation was opened up. And me, just like so many of y'all out there, like, I'm like, man, I do not like meditating, I do not like calming down, like slowing down.  [00:17:31] Jason: I mean, especially if we're addicted to dopamine and adrenaline, like slowing down feels like a waste of time.  [00:17:39] Sam: Oh yeah, it does. And so you, most of you have heard of dopamine, serotonin, and adrenaline slash norepinephrine, right? That's only 20 percent of our neurotransmitters. [00:17:51] Sam: Okay. What's the other 80 percent glutamate and GABA, right? Glutamate is the exitory neurotransmitter. So that's what animates our body. Think glutamate animate, but then GABA is what balances that. So GABA helps slow things down, shut things down. And it's kind of interesting that popular culture slash society, like you don't hear much about GABA. [00:18:13] Sam: And the reason why is because they're selling us GABA in the form of alcohol. Alcohol is a huge GABA receptor connector, so it just hits the GABA and you feel kind of calm and relaxed. And so people love alcohol to be social because you want to be in a slight more parasympathetic state to be social, right? [00:18:30] Sam: Because high stress doesn't lead to—  [00:18:32] Jason: What about scrolling on social media?  [00:18:33] Sam: Social media is going to be hitting dopamine, not so much the GABA. But scrolling social media is going to be giving dopamine, new information. Ooh, new information. I learned something new, like boom, like that constant external input stimulus. [00:18:45] Sam: But when you look at the importance of GABA and you understand that a lot of us aren't making it on our own, which is why we're staying in such a high stress state all day. Yeah. And then we take a GABAergic, like GABA or a benzo or some weed or something that, that can hit that, that GABA receptor instead of making our own endogenous GABA. [00:19:02] Sam: And that's what happens when you're in a parasympathetic state is your body is creating its own GABA to balance out the brain. And that's what drove me to developing a suite of tools called Peace on Demand that I have at my wellness center that are physics based modalities that drop you into that parasympathetic state without sitting there fighting against your brain and trying to force yourself to meditate. [00:19:21] Sam: And then also with hyperbaric oxygen therapy, that's another tool that induces a parasympathetic state over the course of the treatment. And so I found tools because my brain, I had a hard time controlling with the autoimmune disease that I had and how stressed and on fire my brain was, I had a lot of difficulty finding that space, but without those tools, you can still utilize things like breath work, even if it's just longer exhale than the time you're inhaling or like four seconds in, you know, hold for a little bit and then eight seconds out or seven seconds out. [00:19:48] Sam: That, that's just like the simplest form of breath work to kind of activate the vagus nerve and slow down that that nervous system and get you into a more parasympathetic state but it's really interesting when you see that some of the most creative people and the most successful people, they're not super high strung. At a certain point, you'll see a lot of successful people that are high strung. Push, push hustle. [00:20:10] Sam: But then you go to that next level. You look at like the Elon's of the world, or, you know, so these people are on that next level. You watch them speak. They're calm. They have this, you know, they go hype on at times to like reach certain goal. But then they also have that balance. So the key is balance. [00:20:26] Sam: Don't beat yourself up for when you feel stressed out. Just make sure that before you continue that stress rollercoaster, like find some space to find some peace, do some breathing, take a pause, give yourself that chance to take a break. That'll start developing some resiliency in your nervous system so that you don't burn out. [00:20:42] Jason: Yeah, it does seem like really high performers are highly adaptable to, you know, situations. So they move and adapt quickly. It seems like they are able to maintain some calm, but they also are really quick thinkers, like their thinking seems to be faster than normal. I notice for me, I get really frustrated with team members when they're not— [00:21:05] Jason: I'm like, "come on, this is super quick. Like, look how fast I can do this." And I'm like, "keep up." And so that becomes a little bit of a frustration. I'm like, why is everybody slow? I saw this really interesting thing. My son sent me this and he's really into football. And I guess there's some quarterbacks that are now training with VR. [00:21:23] Jason: Playing the game in VR and but they're doing it at 1. 5 speed. And so they're getting used to everything being fast and they've adapted to that. So then when they go and play, it feels like everything's in slow motion. And I was like, wait a sec. I listen to telegram messages at two speed. I listened to audio books at two, between 1.8 to two speed. Like, so my brain is probably more adapted to speed.  [00:21:49] Sam: Yes.  [00:21:50] Jason: And and so I'm able to process, I was just hanging out with somebody who has a lot more money than me, who runs, who's the CEO of Real, Sharran Srivatsaa. And he talks really fast and he thinks really fast. Like this guy is sharp. [00:22:03] Jason: And I'm like, how does he move so fast? You know? But also and he doesn't seem like stressed out or anything. One of the things I've noticed, maybe like sparks this GABA sort of thing is just for me, reading? Just reading, actually reading not like high speed audiobooks, but sitting down with a book and processing information, my body's in a calm state. I feel a really deep calm where I'm in a flow sort of state reading and absorbing and processing information. So I found that can be a really good tool for me. [00:22:34] Jason: Sarah and I go do your peace on demand thing, which is just awesome. And a game changer. It's really been helpful for Sarah. It's kind of, I compare it to doing a float session, having a really good float session which doesn't happen every time you do a float session, but it happens every time you do Peace on Demand and you don't have to get wet and naked, and nothing gets in your eyes or ears on accident sometimes and stings. [00:22:54] Jason: So that's nice. The other thing I've noticed is just walking. So I went and did EMDR therapy for a while, for like a year with a therapist, bilateral stimulation, both sides of the brain is the concept. And then I noticed like, well, walking is bilateral stimulation. And so that's like a free, very cheap version of EMDR therapy is just to go on walks. [00:23:14] Jason: And rather than running, which is like, Hey, stress response. I found walking is very calming, especially if I'm really stressed. If I go for a walk, it kind of signals to my body, "Hey, you're okay. You're not being chased by a saber tooth tiger right now." So your fight or flight, calm down. So those are the things that work for me. [00:23:32] Jason: I don't know, but those are great tools. I don't know.  [00:23:35] Sam: Yeah. So what those are doing are like, you mentioned a keyword there and that's safe, right? And so you're creating these environments. One, you're reading a book, gaining new knowledge, and you're not cramming the book in a stressed out state to try to memorize it for a test, right? Which so much of us get programmed in school at an early age, that like reading means like, focus hard and stress out over what you're reading. [00:23:56] Sam: But if you allow yourself to relax into that flow state, and you mentioned flow state as well, flow doesn't happen when you're in super high stress state. Some people We'll try to say, "Oh yeah, I'm in flow" because they've got like dopamine coursing and cortisol coursing and  [00:24:10] Jason: they're like manic and going crazy.  [00:24:12] Sam: Yeah, exactly. [00:24:13] Jason: They're busy, but they're not productive.  [00:24:15] Sam: Yeah. And when you get productive and when you feel like you're going fast and your team isn't responding fast enough, like you have that adaptability, you have that BDNF that's really efficient in your brain because you practice going in and out of these states and you spend a lot of time in this flow and in this GABA balanced state Where you're not hyper stressed out and one one thing that also on a biochemistry level explains some of this is: in a sympathetic nervous system response, your body is trying to find as much glucose as possible to burn glucose for fast quick energy, which creates oxidative stress on the body, which creates inflammation. And then your body has to like go clear out all the junk but it doesn't care that it's creating a bunch of junk to clear out, because it's trying to help you survive short term. [00:24:59] Sam: When you're in a parasympathetic state, you're looking at a—  [00:25:02] Jason: Does it make you crave sugar then?  [00:25:03] Sam: Yeah, so high stress makes you crave sugar. Whereas parasympathetic state, you're on a more fat burning metabolism. You're not creating as much oxidative stress. You're like expressing longevity genes. You're expressing anti inflammatory genes. [00:25:16] Sam: Your body literally shifts into almost a different state, not just mentally, but biophysically and biochemistry wise all throughout your body. You adapt based on the nervous system state that you allow. And that's where it does come down to personal responsibility to make the choice to start practicing finding this state that will empower so much more potential for your life than that narrow band of, you know, survival programming and high stress thinking. [00:25:46] Sam: And then it's better for your health longterm too, because you're not just compounding oxidative stress nonstop and then needing those negative inflammatory inputs to make your dopamine stay high. And you can just find that peace. And then you'll find a much higher level of performance and that flow state will start just happening naturally constantly, which is what's been happening for Jason as he's been practicing these things as well. [00:26:08] Jason: Got it. Okay. Very cool. So little teaser, what are you going to talk about a little bit at DoorGrow Live that will be revelatory or helpful for people that might be a little bit stressed in their business or are wanting to take their performance to the next level? And I just, I want to point out, the difference I've noticed just in clients doing time studies and things like this. [00:26:32] Jason: Some of my clients will, we can see in their time study that they, it takes them in the latter half of the day, like the afternoon, an hour to do stuff that takes them 10 minutes in the morning. They're just, they're running out of brain chemicals. They're running out of like, what are neurotransmitter chemicals that they produce while sleeping? [00:26:51] Jason: They're now no longer productive and efficient, even though they're working really hard and they're really busy. And so, so yeah, maybe you could tease a little bit. What could we talk about there that might optimize their productivity so that they could actually feel superhuman and get two to three times the amount of output with the same amount of work or stress or effort? [00:27:14] Sam: Yeah, so we're going to go into a little bit more detail on some other aspects of the foundations of performance. So today we focused on nervous system, which is key. But. Controlling our nervous system isn't just as easy as thinking about it. There's some environmental factors. There's some lifestyle choices we can make. Often, we have a really hard time making those changes due to the, those well worn grooves, like, you know, skis on a slope that are really hard to get out of. And so I'm going to help with some simple truths that you'll understand and make it a lot easier to start making small shifts that will create massive change and that don't have to be stressful or induce anxiety or feel hard. It'll actually feel easy. So I'm going to help you understand some fundamental truths about your biology and That will unlock unlimited potential.  [00:28:03] Jason: Yeah, because I think every entrepreneur listening, myself included, I'm sure you as well, have been in those time periods where you feel like you're working so hard and you're investing so much time and energy, and you're going nowhere like it feels like you're just treading water and you're burning yourself out and you're like, "why am I not adding hundreds of doors? Why am I not growing my business? Why am I not getting ahead? Why am I seeing idiots get further along than me?" You know, like, " why is this not working for me?" And and I think that all plays into that like that. Everything you're talking about plays into that.  [00:28:41] Sam: You'll find yourself having permission to make some changes and the permission is a key aspect of that courage and that bravery to choose something different to focus on something different. [00:28:56] Sam: I mean, we all hear where you, where your attention goes, your focus grows, you know, and what you focus on is what you create, you know, all these things. What does that fundamentally and literally mean when it comes to the way we choose our life experience? And what can we create when our choices change and how can we be empowered to make those choices? [00:29:16] Sam: Those are some of the more intricate topics that we'll discuss.  [00:29:19] Jason: Got it. Almost like shifting from feeling like, "Hey, I'm giving up something or sacrificing in some way that in actuality, you're getting more."  [00:29:30] Sam: Oh, so much more. Exactly. So much more. Yeah. Cool.  [00:29:34] Jason: So. Those of you listening, I'm guessing you're growth oriented, growth minded. [00:29:39] Jason: You want to get more. Come to DoorGrow Live. Come hear Sam talk. So cool. Sam, appreciate you coming here on the #DoorGrowShow. If people are hanging out in Austin or curious about what you're up to, how can they find you? Peace on Demand. Tell them about your stuff and how people might be able to follow you or get in touch. [00:29:58] Sam: Yeah. So we have a small wellness center here. It's a private, you know, high touch concierge space, very comfortable here in Austin. And it's open for business by appointment only but just go to beamhyperbarics.Com and you can book an appointment. If you want to reach out to me I am Sam Womack. [00:30:15] Sam: On Instagram or you can send a message through the website. Easier website to remember is beam.do B E A M dot D O. And yeah, just reach out, come hang out. You don't even have to buy something to come in. Just hit me up. We'll make sure that I'm around and we can sit on the couch in the back and talk life. [00:30:34] Jason: All right. Awesome, Sam. Appreciate you coming on and excited to have you at DoorGrow Live.  [00:30:40] Sam: Yeah. I'm excited as well. Looking forward to it. I love what you're doing. And I think the steps that you're taking to help empower people beyond just showing them tactics and strategies, but helping them live a more fulfilled and empowered life. [00:30:50] Sam: That's what it's all about. So thank you for that work you're doing.  [00:30:53] Jason: Yeah, absolutely. We've just noticed like we can give them all the right tactics and strategies, but if they don't incorporate the other things, it's kind of like you're trying to run a race up the mountain with rocks in your backpack, like boulders, you know, it's just, it's so much more efficient if we get everything else in alignment and usually it's never the business piece that's really what's holding them back. It's not the tactics it's mindset. It's their mental health. It's like everything else, their family. Yeah. So we're excited to bring you and some others that are going to just unlock a lot of things for our clients and for non clients that are coming to DoorGrow Live. [00:31:32] Jason: So appreciate you.  [00:31:34] Sam: Yeah, you bet. Thank you. And just one last thing is you guys are all doing such a great job too. Like, don't think of this as any type of a criticism or, "Oh, you're not doing good enough." Like you're doing such an excellent job with the tools that you were programmed with the upbringings you had with the environment you're in. [00:31:48] Sam: So like, just look at it as a chance to learn something new and be empowered by it. But you guys are all doing such a great job. And so keep it up.  [00:31:56] Jason: Yeah, everybody's doing the best they can with their current limited access to knowledge and resources that they put out. Whatever. All right, cool. Awesome, Sam. I'll let you go. All right. So, if you are a property management entrepreneur and you're wanting to add doors or increase your profit or lower your stress, reach out to us at DoorGrow we would love to help you grow and scale your business. You can check us out at DoorGrow. com. And if you're wanting to join our free community, get a little bit more info about us, hang out with some other property managers, go to DoorGrow club. com to join our free community and connect with other property managers and get some cool free stuff. And until next time to our mutual growth, everybody. Hope you all crush it. Bye everyone. [00:32:38] Jason: You just listened to the DoorGrowShow We are building a community of the savviest property management entrepreneurs on the planet in the DoorGrowClub Join your fellow DoorGrow Hackers at doorgrowclub.com Listen everyone is doing the same stuff SEO PPC pay-per-lead content social direct mail and they still struggle to grow at DoorGrow We solve your biggest challenge getting deals and growing your business Find out more at doorgrow.com Find any show notes or links from today's episode on our blog doorgrow.com and to get notified of future events and news subscribe to our newsletter at doorgrow.com/subscribe until next time take what you learn and start DoorGrow hacking your business and your life.

The MindBodyBrain Project
Exploring the Metabolic Treatment Frontier in Psychiatry with Dr. Matt Bernstein

The MindBodyBrain Project

Play Episode Listen Later Feb 28, 2025 67:41 Transcription Available


In a groundbreaking dialogue, I sat down with Dr. Matt Bernstein, a veteran psychiatrist and the CEO of Accord, to explore how metabolic health impacts mental well-being. This illuminating conversation delves into the innovative field of metabolic psychiatry, revealing how metabolic interventions offer a new frontier for treating mental health disorders. What You'll Learn: • Understanding Metabolic Psychiatry: Dr. Matt Bernstein introduces the concept of Metabolic Psychiatry, emphasising how the brain's energy consumption is pivotal to mental health. We dive into how psychiatric conditions can stem from compromised metabolic health, transforming our approach to treatment. • Training for Psychiatry: Dr. Bernstein takes us through his journey to becoming a psychiatrist, highlighting gaps in nutrition education throughout his extensive medical training. • Metabolic Health and Psychiatry: We delve into how metabolic health is crucial for brain function. Dr. Bernstein discusses the energy needs of the brain and how metabolic strategies can serve as powerful interventions for mental conditions. Key Takeaways: • Metabolic Health as a Mental Health Cornerstone: Dr. Bernstein advocates for a foundational approach, building mental health treatments around metabolism. • The Critical Role of Lifestyle: Emphasising the influence of exercise, diet, and light exposure, Dr. Bernstein highlights the potential of lifestyle modifications to transform mental health care. • Pioneering Research and Future Directions: Dr. Bernstein is optimistic about ongoing research that promises to further validate and explain the efficacy of metabolic mental health interventions. However, concerns loom about mainstream psychiatry's willingness to adopt such approaches, reminiscent of challenges faced in epilepsy treatments. Resources: Explore Accord MH to learn more about their innovative approach and services in metabolic psychiatry. Connect with Dr. Matt Bernstein through LinkedIn to follow his journey and contributions to the field of mental health. Support the Conversation: If you found this discussion insightful, subscribe, rate, and leave a review on your preferred podcast platform to help us continue bringing vital conversations to light. Share this post with someone who might benefit from understanding the connections between metabolic and mental health—knowledge is powerful, and this could spark a significant change in someone's life. 00:40 Journey to Becoming a Psychiatrist02:43 Metabolic Psychiatry Explained03:32 Historical Context of Metabolic Treatments03:52 Ketogenic Diet and Epilepsy08:45 Challenges in Psychiatric Training14:15 Personal Story: Son's Mental Health Journey17:19 Rethinking Psychiatric Diagnoses21:40 Metabolic Treatments for Mental Health24:01 Human Evolution and Modern Health Challenges29:43 Role of Ketogenic Diet in Mental Health35:50 Ketogenic Diets and Autophagy35:58 Reducing Oxidative Stress36:43 Impact of Simple Carbohydrates37:26 Neuroinflammation and Mental Health38:19 Ketogenic Diet and Neurotransmitters42:00 BDNF and Brain Health44:39 Microbiome and Gut-Brain Axis50:01 Hormetic Polyphenols53:23 Personalised Nutrition and Gut Health54:50 Mitochondria and Metabolic Health57:47 Accord's Comprehensive Mental Health Program01:01:10 Future of Mental Health InterventionsSee omnystudio.com/listener for privacy information.

The Wellness Mama Podcast
How Knowing Your Child's Genetics Can Make Parenting Easier with Dr. Erika Gray

The Wellness Mama Podcast

Play Episode Listen Later Feb 3, 2025 39:12


Episode Highlights With Dr. Erika GrayImportant perspective about genetics and how to use this information for the biggest advantageThe nuance when it comes to children and genes Genes do not exist in isolation and why focusing on one gene is not helpfulHow understanding genetics helped her teens (and mine)What COMT is and how this comes into play with influencing our worldviewFast COMT break down dopamine and norepinephrine faster (linked to moving around, not sitting still, etc.)How this understanding of genetics can relate directly to how we parent Yet another reason protein is so important, especially for kids and teens Genes related to serotonin and dopamine and neurotransmittersWe have 2-5 lbs of bacteria in our gut, and there is a gene called FUT2 that ties to lower levels of bifidobacteria, and this can be linked to anxiety, longevity, and moreUnderstanding choline genes and why this is a game changer for so many people, and this is critical for pregnancy and brain development Some caveat around MTHFR and why we might be overdoing our response to thisSerotonin-related genes to look at if you get your kids' genes testedWhat BDNF genes can tell youMC4R is a snacking gene, and how to understand thisBitter taste receptor genes and how these can make kids more pickyResources We MentionMy Toolbox Genomics - Use code wellnessmama for a discountKion Aminos

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Surprisingly, one of the earliest signs of dementia involves the retina. There is a high correlation between problems in the retina and problems in the brain. Problems with night vision or central vision, floaters, and light sensitivity issues are the earliest signs of dementia. Some people develop amyloid-beta plaquing on the retina and may experience problems differentiating shades of grey and other colors. Researchers have found high levels of microbes, typically found in the mouth, in the brains of Alzheimer's patients. When people die from dementia, it's usually caused by an infection such as a UTI or lung infection. For some people, surgery can be too much on the body and lead to death. Some people with dementia have a slow, progressive degeneration of the brain to the point they're bedridden and stop eating and drinking, which ultimately leads to death. Focus on cleaning your brain and reducing inflammation for dementia prevention. The glymphatic system cleans the brain, mainly at night, which is one of the primary purposes of sleep. This system removes malformed proteins and plaquing and rejuvenates the brain. Anything that inhibits sleeping may increase your risk for Alzheimer's, heart attacks, strokes, cancer, blood sugar issues, and type 2 diabetes. Sleep apnea can also be problematic. You need 8 to 9 hours of sleep! Alcohol significantly interferes with REM sleep and is very damaging to brain health. To prevent Alzheimer's, you must flood the brain with oxygen. Exercise is one of the best ways to do this! Exercise stimulates the growth of brain cells and the hormone BDNF (brain-derived neurotrophic factor). Adequate sun exposure and high amounts of vitamin D can help support healthy sleep. A diet high in sugar and carbohydrates can starve your neurons. Brain cells love ketones! To get into ketosis, you must lower your carbohydrate intake. If you have any early signs of dementia, try taking ketones as a supplement or MCT oil. Niacin may also be helpful. Take 50 mg daily, slowly increasing to 500 mg per day. Amyloid Beta Plaquing Study: https://pubmed.ncbi.nlm.nih.gov/20550... Why We Sleep Book Link (Matthew Walker): https://www.amazon.com/Why-We-Sleep-U... DATA: https://www.sciencedirect.com/science... https://www.nia.nih.gov/news/changes-... https://alz-journals.onlinelibrary.wi... https://www.science.org/doi/10.1126/s...

Huberman Lab
How to Use Exercise to Improve Your Brain's Health, Longevity & Performance

Huberman Lab

Play Episode Listen Later Jan 6, 2025 109:32


In this episode, I discuss how different forms of exercise impact brain health and performance in both the short and long term. I explain how many of the positive effects of exercise on brain function occur through the action of specific neurochemicals that increase alertness. I also cover how to best time exercise and which specific types of exercise to include in your weekly routine to maximize benefits for your brain. Additionally, I explain how certain types of exercise trigger the release of a hormone from your bones called osteocalcin, as well as brain-derived neurotrophic factor. Together, these substances increase neuroplasticity and enhance learning. The positive effects of exercise on brain oxygenation, blood supply, and fuel utilization are also discussed. Listeners will learn how to design a weekly exercise program that optimizes physical fitness, brain health, longevity, and performance, along with the mechanistic logic behind those recommendations. Find show notes with articles, resources and more at hubermanlab.com. Pre-order Andrew's upcoming book, Protocols: https://go.hubermanlab.com/protocols Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman David: https://davidprotein.com/huberman Function: https://functionhealth.com/huberman Maui Nui: https://mauinui.com/huberman Timestamps 00:00:00 Exercise, Brain Health & Performance; Protocols Book 00:04:03 Sponsors: BetterHelp & Helix Sleep 00:06:55 Brain Health, Cardiovascular & Resistance Training 00:11:51 Exercise & Positive Impact on Brain Performance; Arousal 00:18:20 Learning & Arousal 00:23:18 Sponsors: AG1 & David 00:26:01 Exercise & Acute Learning 00:29:16 Tool: High-Intensity Training & Cognitive Flexibility; Over-Training 00:33:32 Long-Term Brain Health; Tool: Exercise “Snacks”, Cognitive Performance 00:36:57 Exercise, Brain & Body Energy, Adrenaline, Norepinephrine 00:44:08 Adrenal “Burnout”?; Exercise to Increase Energy, Adrenaline 00:48:20 Tool: Core, Compound Movements; Mind-Body Connection 00:53:58 Sponsor: Function 00:55:45 Bones, Osteocalcin, BDNF & Hippocampus; Tool: Jump Training 01:01:30 Exercise, Fuel, Multifactorial Pathways; BDNF & Activity 01:05:06 Lactate, Astrocytes & Brain Function; VEGF & Brain Health 01:11:17 Tools: Zone 2, High-Intensity Training, Time Under Tension Training 01:19:54 Sponsor: Maui Nui 01:21:37 Tools: Time Under Tension; Explosive Jumping, Eccentric Control Training 01:25:30 Injury & Exercise, Illness 01:28:09 Sleep; Injury, Sleep-Deprivation & Exercise 01:33:51 SuperAgers, Anterior Mid-Cingulate Cortex, Grit & Persistence 01:42:04 Tool: Embrace Challenges; Deliberate Cold Exposure, Rope Flow 01:47:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

The Liz Moody Podcast
The 10 Best Health Tips From 2024: New Science Of Cancer, Relationships, Brain Health, Weight Loss, And More

The Liz Moody Podcast

Play Episode Listen Later Dec 18, 2024 85:25


Heading into the new year and reflecting on this past one, I'm giving you the best-of-the-best clips from experts on the podcast in 2024 – from nutrition to mental health to improving your work-life balance and everything in between. The full episodes are linked below, so be sure to listen to any that you might've missed to get all the life-changing information! 2:28 Blood Tests with Dr. Shah 6:43 Break Up with Your Phone 13:09 Cancer and Diet with Dr. Sanjay Juneja 19:10 Couples and Anger 26:41 Becoming Optimistic 31:33 Eating Well 37:01 Pain vs. Suffering 42:40 Dopamine and Reward-Seeking 48:27 Forming Meaningful Friendships 52:51 Emotional Brain Training 56:36 Work-Life Balance Tips with Simone Stolzoff 1:04:35 What Does Cortisol Do? 1:12:28 The Novelty Rule Listen to the full episodes: Episode 224: Secrets to Optimal Health with Dr. Darshan Shah Episode 265: 5 Things I Did to Stop Scrolling Episode 217: Why So Many People Are Getting Cancer and What You Can Do Today to Protect Yourself with Dr. Sanjay Juneja Episode 216: Fighting Can Make Your Relationship Better—If You Do It This Way with Drs Julie & John Gottman Episode 220: Anyone Can Become More Optimistic—Here's How with Dr. Sue Varma Episode 227: The REAL Science of Eating Well: Cutting Through Social Media Confusion To Find Your Best Diet Episode 245: How Are Millennials And Gen Z Already Having A Midlife Crisis? (Why They're So Burnt Out + How To Deal) Episode 252: Neuroscience Hacks For Optimizing Dopamine, Serotonin, Oxytocin, BDNF, And More Episode 240: The Secret To Making Soul Satisfying Friends As An Adult (Avoid The Mistake Everyone Makes!) Episode 269: This Revolutionary Approach To Weight Loss Is Sustainable, Fun, & Proven To Last—So Why Is No One Talking About It? Episode 228: Why We Have No Work/Life Balance + How To Fix It Episode 257: What Social Media Gets Wrong About Hormones: a Guide to What's Real & What's BS Episode 258: The Novelty Rule: How To Use My Neuroscience Hack That's Changing Millions Of Lives Ready to uplevel every part of your life? Order Liz's book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now!  To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome This episode is sponsored by: MasterClass: go to masterclass.com/LIZMOODY for up to 50% off. AG1: visit drinkag1.com/lizmoody and get your FREE year supply of Vitamin D and 5 free travel packs today. ZocDoc: go to ZocDoc.com/LizMoody and download the Zocdoc app for FREE and book a top-rated doctor today. LMNT: go to DrinkLMNT.com/LizMoody to get a free LMNT sample pack with any order. Puori: go to puori.com/LIZMOODY and use promo code LIZMOODY for 20% sitewide. Seed: go to seed.com/lizmoody and use code LIZMOODY for 25% off your first month. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast.  This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 289. Learn more about your ad choices. Visit megaphone.fm/adchoices