POPULARITY
Jejum intermitente não é só para emagrecer. Neste episódio do Made in Brasil, a Dra. Maíra Soliani explica, com base científica, como o jejum intermitente pode melhorar clareza mental, foco e produtividade, além de apoiar saúde metabólica e longevidade.
Vitamin D testing is vital for tailoring doses to optimize health—but regulators are conducting a campaign to deny coverage; Can magnesium be taken simultaneously with blood pressure meds? Lifelong learning delays Alzheimer's onset by 5 years; Your MRI says you have a bum shoulder—but 99% of people show abnormalities even when they have no discomfort; Saunas can help stave off dementia.
VO2 max is one of the strongest, most measurable predictors we have of longevity; and for midlife women, getting your cardio strategy right matters. In this episode, I break down the real truth behind the “HIIT vs Zone 2” debate, and show you how to use both in a way that supports energy, brain health, and long-term performance, including what Zone 2 training really improves, and what HIIT actually changes in your body. You'll also learn how to programme cardio in midlife so you increase VO2 max without disrupting sleep, strength training, or your ability to recover. By the end, you'll have a clear weekly framework to build cardiovascular fitness safely in midlife, even if you're time-crunched, plus two science-backed interval workouts that reliably improve VO2 max. WHAT YOU'LL LEARN • Why VO2 max is a powerful longevity marker (and why it matters in midlife) • The difference between Zone 2 and HIIT (and what each one is for) • What Zone 2 builds (aerobic base, mitochondria, recovery capacity) • Why Zone 2 often “feels pointless” for high-achieving women (and what to do instead) • How HIIT improves VO2 max, insulin sensitivity, and metabolic health • The brain benefits of Zone 2 vs Zone 5 (BDNF, lactate, blood flow) • Why “more intensity” often backfires in midlife (sleep, stress, injury risk) • The progression hierarchy that protects your joints and results• How many HIIT sessions women actually need (and when it's too much) • Two evidence-backed HIIT workouts: micro-intervals + the Norwegian 4x4 • A simple weekly template that works even with 30 minutes a day • How to combine resistance training + cardio in the same day for best results VALUABLE RESOURCES 10 Habits That Help Me Reverse My Biological Age (Free Guide)
In this episode, I sit down with neuroscientist Dr. Louisa Nicola to unpack what women actually need to know about Alzheimer's risk, cognitive decline, and long term brain protection. We break down APOE genetics, advanced blood biomarkers that can now detect amyloid and tau with remarkable accuracy, and why brain health is inseparable from metabolic health. Louisa explains how muscle acts as a metabolic sink for glucose, why resistance training and high intensity intervals stimulate BDNF, and how sleep drives the glymphatic system to clear amyloid from the brain. If you want practical tools to assess your personal risk, understand your labs, and build a proactive prevention plan decades before symptoms appear, this conversation is for you. → Leave Us A Voice Message! Topics Discussed: → What does APOE4 mean for Alzheimer's risk? → Can exercise prevent cognitive decline? → Do blood tests detect early Alzheimer's? → How does perimenopause affect brain health? → Does hormone therapy reduce dementia risk? Sponsored By: → Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/KELLY and save up to 39% off your Mitopure® Gummies. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → Cozy Earth | Head to https://cozyearth.com and use code BEWELL for up to 20% off. And if you get a post-purchase survey, make sure you tell them you heard about Cozy Earth right here at the Be Well by Kelly podcast. → LMNT | Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/Kelly. Find your favorite LMNT flavor, or share with a friend. Timestamps: → 00:00:00 - Introduction → 00:01:27 - Mission to end Alzheimer's → 00:03:28 - Women's rate of Alzheimer's → 00:04:11 - Alzheimer's overview → 00:07:44 - Education level & health → 00:09:57 - Anatomy → 00:14:16 - Neuroplasticity & glucose → 00:19:38 - Amyloid-beta → 00:26:41 - LDL Cholesterol → 00:28:36 - Preparing for menopause → 00:31:30 - Blood testing recommendations → 00:34:26 - Lifestyle interventions → 00:39:05 - Nutrition & the MIND diet → 00:42:19 - Zone 2 vs zone 5 training → 00:44:36 - Lactic acid → 00:47:58 - HRT is protective → 00:50:19 - When to test for HRT → 00:51:56 - Testosterone + brain health → 00:53:40 - Cognitive reserve → 00:57:12 - Hot flashes → 00:58:13 - Quick fixes → 01:00:01 - Brain surgery → 01:05:38 - The brain code Show Links: → Function | Own your health for $365 a year. That's a dollar a day. Learn more and join using my link. Visit https://www.functionhealth.com/bewellbykelly and use gift code BEWELL25 for a $25 credit toward your membership Further Listening: → How to Take Control of Your Health in a Toxic Food Landscape | Max Lugavere Check Out Louisa: → Instagram → The Brain Code Check Out Kelly: → Instagram → Youtube → Facebook
Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our guest, Dr Majid Fotuhi, a Harvard- and Hopkins-trained neurologist who has treated thousands of patients, explains why common forgetfulness isn't the same as cognitive decline and how simple daily choices can restore sharpness at any age.We break brain health down to four core levers: increase blood flow, reduce inflammation, enhance the brain's cleaning systems, and minimize plaques and tangles. Then we map those levers to five daily pillars you can actually do: exercise, sleep, nutrition, stress reduction, and learning. You'll hear why exercise is the highest-yield habit for cognition, how BDNF acts like fertilizer for the hippocampus, and what happens when sugar spikes and insulin resistance quietly shrink your memory center. We also get practical about sustainable nutrition, from curbing glucose swings to deciding whether keto is worth it for your lifestyle.Beyond biology, we dig into the mindsets that keep the brain young. Boredom—of the unplugged, daydreaming kind—can unlock creativity and problem solving. A clear sense of purpose measurably lowers dementia and stroke risk while making healthy choices easier to keep. We share the telltale red flags (like repeating questions) versus normal lapses (like misplacing keys), plus the personalized assessment approach that uncovered treatable factors in patients who feared Alzheimer's. If you want a realistic timeline, expect noticeable gains in about 12 weeks when you dial in the five pillars.Ready to build a resilient, younger brain? Follow the five pillars, personalize your plan, and start today with one small step—take a brisk walk, protect your sleep window, or learn something challenging you actually enjoy. If this conversation helped you, tap follow, share it with a friend who needs hope, and leave a quick review so more people can find it.https://drfotuhi.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Win a Signed Copy of Lies I Taught in Medical School :https://robert-lufkin.mykajabi.com/pages/review-kit Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd ...
Get AudioBooks for FreeBest Self-improvement MotivationA Simple Way to Boost BDNF for Brain PowerLearn a simple, science-backed way to increase BDNF and support brain growth, memory, and focus. Boost mental performance and long-term brain health.Get AudioBooks for FreeWe Need Your Love & Support ❤️https://buymeacoffee.com/myinspiration#Motivational_Speech#motivation #inspirational_quotes #motivationalspeech Get AudioBooks for Free Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Your self-image shapes your decisions, your perspective and your outcomes. And because your self-image is formed from a very young age, it can be difficult to change the habits, thoughts, and patterns that have been ingrained for decades. Today, you're going to learn a proven framework for improving your self-image and overcoming self-doubt. On this episode of The Model Health Show, our guest is behavioral researcher and educator, Dr. Shadé Zahrai. She's here to share science-backed strategies for shaping your self-image from her new book, Big Trust. You're going to discover how to rewire self-doubt, how to build confidence, and how transforming your self-image can help you reach your potential. Specifically, we're going to discuss the four inner attributes that could be holding you back, and how to sharpen them to improve your self-esteem, mindset, and overall personal growth. Dr. Shadé is an absolute expert in helping folks break free from the mindset blocks that are holding them back. If you're ready to take control of your inner world so you can improve your relationships, decision making, and more, this episode is for you. Enjoy! In this episode you'll discover: The connection between confidence and well-being. (3:29) Why you need to take action to develop confidence. (3:49) What self-image is. (8:21) The truth about changing your personality. (10:58) What the most common self-doubt is, and where it originates from. (13:10) Four main signs that you struggle with self-acceptance. (15:51) How having a creative hobby can help improve your self-esteem. (18:57) The power in simply delaying a decision. (29:51) What imposter syndrome is and how to reframe it. (37:26) How pursuing discomfort can activate BDNF. (43:18) Why comparison can be a sign that you struggle with agency. (47:31) What autonomy is and how it relates to self-doubt. (59:13) How microdosing hard things can get you out of your comfort zone. (1:05:05) Signs you might be struggling with adaptability. (1:15:37) Items mentioned in this episode include: Organifi.com/Model - Use the coupon code MODEL for 20% off + free shipping! DrinkLMNT.com/model - Get a FREE sample pack of electrolytes with any order! Big Trust by Dr. Shadé Zahrai - Order your copy of the book today! The Doubt Profille - Discover your doubt profile & what it's costing you! Connect with Dr. Shadé Zahrai Website / Instagram / Facebook / YouTube Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Organifi and LMNT. Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL at organifi.com/model. Head to DrinkLMNT.com/model to claim a FREE sample pack of electrolytes with any purchase.
Une mémoire n'est jamais qu'un simple fichier dans le cerveau, c'est un fil qui nous relie à ce que nous sommes. Nous ouvrons l'épisode avec des récits sincères tirés de l'expérience de notre propre famille avec la maladie d'Alzheimer, ainsi que du poids silencieux porté par les proches aidants, puis nous passons à ce que la science nous dit aujourd'hui pour protéger l'esprit de demain. L'objectif n'est ni la perfection ni la peur, mais une prévention pratique, ancrée dans la vraie vie.Nous expliquons la différence entre la maladie d'Alzheimer et les autres formes de démence, pourquoi l'espérance de vie moyenne après le diagnostic se situe souvent entre 7 et 10 ans, et comment les habitudes adoptées tôt peuvent bâtir une réserve cognitive. L'activité physique occupe une place centrale : l'exercice régulier augmente le BDNF, renforce les connexions neuronales et soutient la santé vasculaire dont le cerveau dépend. Les entraînements mentaux comptent aussi. La lecture, les mathématiques, l'apprentissage des langues et les jeux de mémoire contribuent tous à garder les circuits cérébraux souples et résistants.Les choix alimentaires complètent l'approche. Nous décortiquons le régime MIND et ses racines dans les modèles méditerranéen et DASH, en mettant l'accent sur les légumes verts feuillus, les petits fruits, les légumineuses, les grains entiers, les noix, les graines, l'huile d'olive et les oméga-3 provenant du poisson ou des algues. Plutôt que de débattre des étiquettes, nous nous concentrons sur les résultats : une alimentation riche en fibres, un apport protéique adéquat, moins de gras saturés et une grande variété d'aliments végétaux riches en antioxydants et en composés phytochimiques comme les anthocyanines et le sulforaphane. Nous apportons aussi de la nuance à la notion d'aliments « transformés », en expliquant comment l'enrichissement peut être utile, pourquoi toute transformation n'est pas néfaste, et à quel moment les produits ultra-transformés commencent à remplacer une nutrition de qualité.Si vous cherchez un point de départ simple, essayez ceci : comptez les couleurs plutôt que les calories et visez trois à quatre couleurs dans chaque assiette. Construisez de petits rituels, une portion supplémentaire de légumes verts, une marche de 20 minutes, un casse-tête hebdomadaire, qui s'additionnent au fil des mois. Votre cerveau, votre cœur et votre futur vous en remercieront. Si cette discussion vous a parlé, abonnez-vGo check out my website for tons of free resources on how to transition towards a healthier diet and lifestyle.You can download my free plant-based recipes eBook and a ton of other free resources by visiting the Digital Downloads tab of my website at https://www.plantbaseddrjules.com/shopDon't forget to check out my blog at https://www.plantbaseddrjules.com/blog You can also watch my educational videos on YouTube at https://www.youtube.com/channel/UCMpkQRXb7G-StAotV0dmahQCheck out my upcoming live events and free eCourse, where you'll learn more about how to create delicious plant-based recipes: https://www.plantbaseddrjules.com/Go follow me on social media by visiting my Facebook page and Instagram accountshttps://www.facebook.com/plantbaseddrjuleshttps://www.instagram.com/plantbased_dr_jules/Last but not least, the best way to show your support and to help me spread my message is to subscribe to my podcast and to leave a 5 star review on Apple and Spotify!Thanks so much!Peace, love, plants!Dr. Jules
Elizabeth Troy shares the hidden world of fascia and how this 'living matrix' impacts anxiety, why traditional stretching isn't enough, and steps to take to finally feel like yourself again.
Send us a textWhat happens when modern neuroscience, ancient plant medicine, and spiritual self-awareness collide?In this powerful conversation, Joey Pinz sits down with Dr. Leah Linder—naturopathic physician, reverend, and co-founder of Setas Seminary—to explore how psilocybin mushrooms are being used responsibly, ethically, and intentionally to support healing from trauma, PTSD, anxiety, addiction, and cognitive decline.Leah breaks down the actual science behind psilocybin—how it reduces neuroinflammation, stimulates brain-derived neurotrophic factor (BDNF), and helps the brain form new neural pathways—while also explaining why integration and nervous system regulation matter far more than the ceremony itself.You'll also hear why psilocybin became a Schedule I substance, how federal religious protections allow safe access today, and why healing isn't about being “fixed,” but about learning to listen to your body and rewrite old stories.This episode is grounded, thoughtful, and eye-opening—perfect for anyone curious about the future of mental wellness, consciousness, and sustainable personal growth.
Join My Private Group: https://theaxioncollective.manus.space/Email List: https://huntershealthhacks.beehiiv.com/Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this episode, I finally dive deep into a peptide I've wanted to talk about for a long time: P21.P21 is what I would call a true brain health peptide. It's not a nootropic in the classic “stimulant” sense, and it's definitely not a limitless-pill type compound. Instead, it works upstream, supporting the brain by upregulating BDNF, enhancing neurogenesis, improving synaptic connectivity, and reducing neuroinflammation.I first heard about P21 years ago through parents of neurodivergent children who were experimenting with intranasal use and seeing meaningful changes. That sent me down the research rabbit hole. Since then, I've used it personally, worked with others using it, and spent a lot of time reviewing the animal data behind it.In this episode, I break down what P21 actually is, how it works mechanistically, why it's often compared to Cerebrolysin (and why it's very different), and where I see its real-world use cases. We talk memory, neurogenesis, Alzheimer's and Down syndrome animal models, traumatic brain injury, vision effects, dosing strategies, safety data, and how I personally cycle it.This isn't hype. There are no human trials yet. But the preclinical data is compelling, and in a world where sourcing Cerebrolysin is harder than ever, P21 stands out as a lighter, more accessible tool for long-term brain health.
Examining the $107B burden of insomnia and its link to a 45% increase in cardiovascular risk, Matt dissects a landmark study of 1,348 participants proving that movement is a potent clinical tool. He also explains how yoga adds nearly two hours of sleep by boosting GABAergic activity, while Tai Chi provides sustained benefits for up to two years.Our host details how exercise facilitates the core temperature drop necessary for consciousness to power down. Matt discusses how movement increases brain-derived neurotrophic factor (BDNF) and turns down the volume on systemic inflammation. In the end, Matt reveals that intentional activity recalibrates the nervous system to help you obtain the best quantity and quality of sleep.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.Clean biological living requires precision. Podcast partner Caraway's non-toxic ceramic cookware eliminates deleterious "forever chemicals" for a seamless, slide-off-the-pan cooking experience. Save $190 on sets plus 10% off at Carawayhome.com/mattwalker. Caraway. Non-Toxic kitchenware made modern.Another of today's partners is Pique. Their circadian hydration system features a morning BT Fountain for skin and cellular health, plus an evening RE Fountain with triple magnesium for recovery. No sugar or fillers. Get 20% off + a free gift at piquelife.com/mattwalker to start your daily hydration ritual.As always, if you have thoughts or feedback you'd like to share, please reach out to Matt or Eti:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube: https://www.youtube.com/@sleepdiplomat
Join us for this episode which is a fast, honest tour through what ketamine can actually do for mental health—without the hype. We sit down with addiction psychiatrist Dr. Mark Hrymoc to unpack where the evidence is strongest, who qualifies, and why IV ketamine often produces quicker relief than nasal esketamine when depression won't budge. From treatment-resistant depression and acute suicidality to anxiety and PTSD, we dig into the protocols that matter: six-session inductions, customized maintenance, and practical strategies for measuring progress with tools like the PHQ-9.We pull back the curtain on how ketamine works at the receptor level—NMDA antagonism, downstream dopamine effects, and BDNF-driven neuroplasticity—and explain why dissociation may help some patients but isn't required for benefit. You'll hear how we screen candidates, manage blood pressure, reduce nausea, and set up sessions with eye masks, ambient music, and a nurse at the bedside so the experience is safe, focused, and grounded. We also get real about addiction risk, clarifying the difference between recreational use and a carefully monitored medical protocol, and how stable recovery timelines factor into clinical decision-making.For PTSD and anxiety, we explore pairing ketamine with psychotherapy and post-session integration to turn insights into change. We compare IV ketamine's dosing flexibility with Spravato's structured pathway, talk costs and coverage, and outline how to taper other meds only after sustained stability. Looking ahead, we spotlight promising research directions—from extending response with adjuncts to early signals for substance use disorders—and why interventional psychiatry is opening a much-needed chapter beyond traditional antidepressants. If you've wondered whether ketamine is a bridge or a destination, this conversation gives you a clear, practical map. Subscribe, share with a clinician friend, and leave a review to help others find evidence-based mental health care.To contact Dr. Grover - ammadeasy@fastmail.com
The sauna is one of the most powerful, research-backed tools for improving cardiovascular health, brain function, athletic performance, and longevity.In this episode, Andrew breaks down the science behind sauna use, including why regular sauna sessions can reduce cardiovascular mortality by up to 50%, improve blood pressure and cholesterol, boost endurance performance, enhance recovery, and support long-term brain health.We also explore how heat exposure triggers heat shock proteins, growth hormone release, increased red blood cell production, and improved detoxification—plus why sauna works best after your workouts, not before.Whether you're an athlete, someone focused on longevity, or just curious about adding sauna use to your routine, this episode gives you clear, evidence-based guidance on how to use sauna safely and effectively.Chapters00:00 Saunas in the Winter01:57 Sauna history: Finland, Russia, Rome06:30 Sauna Boom in the US09:00 Cardiovascular Health12:39 Performance benefits: endurance, blood volume, RBCs + EPO22:00 Heat acclimation + cardio-respiratory fitness + recovery27:30 Muscle preservation: heat shock proteins + sarcopenia31:30 Brain & mental health: dementia risk, mood, BDNF + learning38:00 Cellular repair, detox, pain reliefThe Co-Movement Gym Podcast is supported by Native Path Supplements and Lombardi Chiropractic.
Most women think brain fog in perimenopause is inevitable. It isn't. In this episode, I explain what's really going on: your brain isn't broken, it's running on empty; and that's a solvable biology problem, not a willpower problem. I break down what happens as estrogen and progesterone fluctuate, how that impacts brain energy, and why symptoms like forgetfulness, poor focus, and “slow-motion thinking” can show up even when you're doing everything right. Then I share four science-backed strategies to rebuild a sharper, more resilient brain—covering nutrition, training for cognitive performance, regulating your mental “gears,” and a practical supplement toolkit to amplify the foundations WHAT YOU'LL LEARN: How blood sugar crashes sabotage cognition (and the breakfast fix) Why protein & healthy fats matter for focus in perimenopause The role of omega-3s (EPA/DHA) in neuroinflammation and clarity Why higher-intensity exercise can improve focus via lactate → BDNF How to use training strategically before deep work or high-stakes meetings The 3 Gears framework for focus, creativity, and stress regulation Why micro-breaks between meetings improve engagement and reduce stress buildup The supplement stack discussed (omega-3s, magnesium forms, ubiquinol/CoQ10, B vitamins) How to start with one change and build momentum without overwhelm TIMESTAMPS 00:00 Brain Fog in Perimenopause: What's Really Going On 02:37 Strategy 1: High-Quality Nutrition 05:25 Strategy 2: Exercise for Focus (Lactate, BDNF & Brain Energy) 08:59 Strategy 3: 3 Gears Framework for Focus & Stress 13:05 Strategy 4: The Supplement Toolkit (What Actually Helps) 17:28 How to Reclaim Your Focus & Energy VALUABLE RESOURCES Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend • Longevity Supplement Masterclass – https://academy.angelafosterperformance.com/longevity-masterclass-27 • Omega-3 Episode featuring Dr. Bill Harris – https://www.youtube.com/watch?v=J42kJPyHPoA A BIG thank you to our sponsors who make the show possible Get 10% off MitoQ NAD+ - www.mitoq.com with code ANGELA Get 35% off Timeline Mitopure by visiting this link while the offer lasts - https://www.timeline.com/promotions/angela35 ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS Instagram Facebook LinkedIn Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
Susan Bratton discusses the importance of a healthy sex life, the four pillars of longevity, and divulges secrets to your orgasmic potential (spoiler alert: she claims there are 20 different types of orgasms!).
In this episode of Barbell Shrugged, Doug Larson is joined by longtime co-host Travis Mash and new co-host Dr. Mike Lane for a return visit from one of the show's most popular guests, Dr. Tommy Wood. Tommy breaks down the core thesis of his new book, The Stimulated Mind (releasing March 24), which uses dementia prevention as the headline but is really about boosting cognition at every stage of life. The crew sets the tone early: brain health is not "old people stuff," it's performance, learning, and resilience, built daily through how you live and how you train. Tommy makes the case that "optimization" only works when it fits real life, and that the brain adapts like the body: sleep, nutrition, and exercise support it, but you still have to "train the brain" with demanding learning and skills. He outlines a practical learning dose-response, roughly 30–90 minutes of deep challenge per session, 2–3 times per week as a sweet spot for consolidation, while acknowledging the power of daily touchpoints for habit formation (Doug's Duolingo streak and the "don't break the chain" approach). From there, they go deep on exercise modalities and cognition: aerobic work and interval training improving hippocampal function (memory), high-intensity work potentially driving brain benefits through lactate → local BDNF, and coordinative/open-skill sports (racket sports, dancing, martial arts) producing outsized brain returns for the same physical strain. The conversation closes with a fast but important run through risk, genetics, and lifestyle: Tommy explains ApoE4 as a risk multiplier that's highly environment-dependent, amplifying bad inputs (inflammation, poor metabolic health) but also amplifying the benefits of doing the basics well. They hit the big nutrition levers for cognition; omega-3s, key B vitamins (methylation), vitamin D, iron, plus polyphenol-rich foods (berries, cocoa, coffee/tea), and squash the common "red wine" rationalization by emphasizing net outcomes (sleep and brain volume matter). Finally, Tommy emphasizes the under-rated keystone: social connection and pro-social behavior, arguing that the Mediterranean "diet" is really a Mediterranean lifestyle, and that isolation can erase many of the benefits of even a perfect nutrition plan. Links: Doug Larson on InstagramCoach Travis Mash on Instagram
What if your next big idea isn't hiding in your to-do list, but in your stride? We explore how moving your body can unlock mental clarity, creative problem solving, and a resilient identity you can trust under pressure. This isn't hype; it's a practical playbook backed by neuroscience, sports psychology, and hard-won stories from leaders, creators, and everyday high performers.We break down the embodied confidence loop: small physical wins become mental evidence, which then fuels bolder actions across your work, relationships, and creative pursuits. You'll hear why BDNF and increased prefrontal blood flow make walking, running, and even gentle stretching powerful tools for ideation and focus. We talk posture and presence, drawing on embodied cognition research to show how standing like a leader helps you think like one. From a tech executive who used boxing to transform stage fright into stage presence, to an entrepreneur who scaled past a revenue ceiling after rock climbing rewired his relationship with risk, you'll see how courage and clarity transfer across domains.Then we get tactical. Use the movement breakthrough technique when you're stuck: step away with intention and let motion change your state. Try the power position reset before high-stakes moments. Practice the breakthrough breath to calm the nervous system and widen attention. Build physical anchors—simple gestures that cue confidence on command. If time is tight, micro workouts and walking meetings can deliver outsized gains in decision quality and creativity. Expect resistance and treat it as a signal to move. Choose one stuck area, one small physical practice, and repeat with consistency and intention.Ready to build a body that your mind can trust? Press play, pick your next move, and let movement and mindset compound your results. If this resonated, subscribe, share with a friend, and leave a review to help others find the show.Illuminate Your World with Kore Candles!Kore Candle Company is a brand that specializes in creating unique and high-quality soy candles. Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showhttps://www.kore-fit.com
It's a controversial topic, fasting, especially for women. Dr. Mindy Pelz was teaching women to fast primarily because they wanted to lose weight, but what she was witnessing was women saying things like, "I lost weight, but my hair's falling out. I don't have a period anymore. I sat down with Dr. Mindy Pelz, New York Times bestselling author of Age Like a Girl, hormone expert, and the voice redefining fasting for women - because doing it wrong can wreck your health. We explore why fasting affects women differently, how ketones can restore brain function during menopause, and why understanding your hormonal cycle is critical for metabolic health, cognitive performance, and longevity. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro 01:50 What put Dr. Mindy Pelz on the map 03:14 The truth about fasting vs intermittent fasting 05:13 How the brain uses glucose vs ketones 07:25 Why the brain "eats itself" during menopause 10:14 What is mitophagy and cellular autophagy 13:11 Why autophagy is the body's repair system 15:24 The 12-hour vs 17-hour vs 72-hour fast 17:23 Why women's cycles are disrupted by fasting 19:59 The fasting cycle for women 21:05 Lactate as a fuel source for the brain 23:01 Hemoglobin A1C and insulin resistance 27:36 Understanding CGM data correctly 30:13 Where women should start at 48 32:01 HRT: personal decision or necessity? 34:15 The nervous system shift during perimenopause 38:48 The grandmother hypothesis and evolutionary sensitivity 41:09 The "menopause divorce" phenomenon 44:18 Dementia, Alzheimer's, and women46:17 Dopamine, novelty, and neuroplasticity47:23 Cold water immersion and trauma rewiring51:19 Cold water and cortisol for women53:51 Exercise, BDNF, and brain health55:21 Serotonin, light exposure, and sleep58:00 Glycine, bone broth, and longevity01:02:26 Preparing for perimenopause and menopause 01:04:24 Acetylcholine, storytelling, and memory 01:08:38 Why eggs and cholesterol matter for the brain _______ A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Ketone-IQ: Mental clarity that lasts - without the crash. Visit https://ketone.com/NEURO for 30% OFF your subscription order - PLUS receive a free gift with your second shipment or find Ketone-IQ at Target stores nationwide and get your first shot free! IQBAR: The New Year gives us all a chance to reset. Maximize your brain and body's potential with IQBAR's protein bars, hydration mixes, and mushroom coffees. Text NEURO to 64000 to get 20% off all IQBAR products, plus FREE shipping. Caraway: Visit Carawayhome.com/neuro10 or use code neuro10 at checkout to take an additional 10% off your next purchase. Caraway. Non-Toxic cookware made modern. Cure Hydration: For The Neuro Experience listeners, you can get 20% off your first order at curehydration.com/NEURO with code NEURO. Cure is FSA/HSA approved, so you can use your FSA or HSA funds to stay hydrated the smart way. Jones Road Beauty: Use code NEURO at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Broadcast from KSQD, Santa Cruz on 1-01-2025: An emailer asks about omega-3 supplementation for memory at age 72. Dr. Dawn advises checking that fish oil capsules contain adequate DHA—at least 1,000 mg—since many omega-3 products have low DHA levels. She notes Medicare covers the same testing at standard labs as proprietary labs like OmegaQuant that charge patients directly. Beyond omega-3s, she emphasizes glucose control (hemoglobin A1c below 5.6) since the enzyme that breaks down insulin also clears beta-amyloid, and weight training to raise brain-derived neurotrophic factor (BDNF), which promotes new synapse formation essential for memory. Dr. Dawn reviews Popular Science's top 2025 health innovation: eye drops from Lens Therapeutics containing aceclidine that correct age-related farsightedness for 10 hours. The drops shrink the pupil to increase depth of field, improving near vision by three or more lines on eye charts within 30 minutes without affecting distance vision. Side effects include eye irritation, dimmed night vision, and headache. She describes Duke University's breakthrough allowing heart transplants from circulatory death donors using an on-table reanimation technique. This could expand the pediatric donor pool by 20%—critical since up to 20% of children die waiting for transplants. Dr. Dawn celebrates CAR-T immunotherapy for multiple myeloma, which saved her husband's life. Of 97 heavily pretreated patients, 38% achieved complete remission still present at five years, with over 50% total survival. The therapy removes T-cells, uses CRISPR to add receptors targeting cancer cell antigens, then reinfuses the modified cells. She highlights a UC Davis study showing remote blood pressure monitoring with home technology, education, and coaching dropped patients' average blood pressure from 150/80 to 125/74 in months—low-tech with high impact. Dr. Dawn explains the Nano Knife for prostate cancer, which uses localized electrical pulses delivered through thin wires to destroy tumors while sparing surrounding nerves. This minimally invasive approach could reduce erectile dysfunction and incontinence common with traditional surgery. She describes Gilead's Sunlenca, a twice-yearly injection for HIV prevention that's 99% effective. At $14,000 per injection in the US, proceeds help fund access in resource-limited countries where it can be distributed like a vaccination. Dr. Dawn discusses Journavx (suzetrigine), a new non-opioid pain medication working on sodium channels to block pain signals before reaching the brain. At $30 for 50 pills on GoodRx, it offers an alternative for surgical pain in patients with addiction history or genetic vulnerability to opioid dependence. She details the landmark case of Baby KJ, the first person to receive personalized CRISPR gene therapy. Born with a CPS1 enzyme deficiency causing toxic ammonia buildup, KJ was too small for liver transplant. Scientists identified his specific mutation and used CRISPR base editing delivered via lipid nanoparticles to correct a single DNA letter—changing an A to G—in his liver cells which restored enough function to be discharged home. Dr. Dawn reports surprising findings that COVID mRNA vaccines amplify cancer immunotherapy. Lung cancer patients who received COVID vaccination within 100 days of checkpoint inhibitor treatment had 56% three-year survival versus 31% for unvaccinated patients. The mechanism is unknown but may involve mRNA generally alerting the immune system. She revisits research showing Zostavax shingles vaccination reduced dementia risk by 20% over seven years. A natural experiment in Wales—where an age cutoff created comparable vaccinated and unvaccinated groups—provided strong evidence that preventing herpes zoster inflammation protects brain health. Dr. Dawn concludes with Huntington's disease breakthrough: microRNA therapy delivered by virus directly into the brain slowed disease progression by 75% over three years. The microRNA binds to Huntington protein mRNA, preventing ribosome translation and toxic protein production. Some patients returned to work; others expected to need wheelchairs are still walking.
Send us a textCellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's.TOPICS DISCUSSED:Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR drives cell division; their synchronization determines healthy modes, while desynchronization causes diseases.Fructose as a dose-dependent mitochondrial toxin: High fructose intake inhibits AMP kinase, reducing mitochondrial function and diverting energy to fat storage; it is dose-dependent, like alcohol, and unnecessary in the diet.Obesogens & endocrine disruptors: Chemicals like tributyltin (TBT) alter gene expression across generations, promoting obesity unrelated to calories; modern exposures increase reactive oxygen species (ROS), burdening cells.Fetal & neonatal development: Maternal diet, especially high sugar or formula feeding, can cause neonatal obesity and fatty liver; breastfeeding supports proper jaw development and oxygen intake.Brain metabolism & Alzheimer's: The brain's high energy needs make it vulnerable to mitochondrial issues and ROS; energy deficits from diet, stress, and toxins lead to synapse loss and inflammation, treatable via prevention.ROS & health: Mitochondria produce ROS as a byproduct of ATP generation; excess from diet or environment causes damage, but antioxidants and lifestyle can mitigate risks.PRACTICAL TAKEAWAYS:Limit added sugars in your diet to reduce mitochondrial stress and ROS, focusing on whole foods over ultra-processed items for better metabolic health.Prioritize breastfeeding for infants when possible to support proper physical development and reduce future metabolic risks.Incorporate regular exercise and social activities to manage stress and boost brain-protective factors like BDNF, aiding neurodegeneration prevention.Get adequate sleep to regulate cortisol and maintain cellular energy balance, helping prevent brain fog and chronic diseases.ABOUT THE GUEST: Robert Lustig, MD is a pediatric endocrinologist and Professor Emeritus at the University of California, San Francisco, with a background in neuroendocrinology and obesity research.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
What if the gap between your age and your energy is wider than you think—and fixable? That's the wager we make as we sit down with longevity strategist Bob Gilpatrick to unpack why most people lose health, not just time, in their final decade and how to reverse that trend with measurable steps. We trace his journey from a near-fatal crash at 17 to a career spanning plant science roots, healthcare leadership, and breakthroughs that blend targeted nutrition with mind-body mastery.We get practical fast: CRP as a “burn rate” for your body, why keeping it below 0.5 changes everything, and how a complete nutrient strategy powers real mitochondrial energy instead of caffeine jitters. Bob explains epigenetic reprogramming—plant-derived, purified molecules that nudge gene sets for muscle, energy, NAD, and BDNF—plus why they can outperform complex peptide stacks at a fraction of the cost. He pairs these advances with essential building blocks: amino acids, enzymes, and minerals that allow your body to build what your genes request. The result? Faster strength gains, better motivation, and noticeable changes many feel within days.We also go beyond biology to the beliefs that block action. You'll hear how EFT tapping and havening calm the nervous system, reduce cravings, and resolve grief or fear by changing brain states in real time. From cartilage support that challenges “once it's gone, it's gone” to sustainable weight loss that protects muscle, this episode is a blueprint for adding strong, clear years—healthspan—to your life. If you're ready to test, adjust, and prove it in your own bloodwork and daily energy, this conversation gives you the steps and the science.Subscribe, share with a friend who needs a push, and leave a review telling us the one change you'll make this week. Then visit boomerboost.com for details and use promo code Omar at checkout.Join the What if it Did Work movement on FacebookGet the Book!www.omarmedrano.comwww.calendly.com/omarmedrano/15min
Consistently moving your body in a way that you enjoy is the best route to optimal health. However, in recent years emerging science has shown the benefits that sprint training can have on human health. On this episode of The Model Health Show, you're going to learn about the science of sprinting. Today's guest, Cynthia Monteleone is a 400-meter world champion masters sprinter and decathlete who ran her fastest times in her 40s. Cynthia is also a metabolic practitioner who works with clientele ranging from Olympians to everyday folks. She is an expert on sprinting over 40, and on today's show she's sharing the top 10 reasons why sprinting is better than endurance training for longevity. You're going to learn how sprinting can affect everything from your gut health to your heart health, the best ways to burn fat, and more. Cynthia is also sharing her personal experience becoming an athlete during midlife and how beginners can start sprint training. Cynthia's message is that it's never too late to empower yourself to reach your goals, and I hope this episode resonates with you! In this episode you'll discover: The top ten reasons why sprinting is better than endurance training for longevity. (2:43) How endurance training impacts gut health. (4:50) The link between sprinting and BDNF production. (5:18) How sprinting impacts fat burning. (7:57) Why sprinting can aid in heart health. (13:18) What dynapenia is. (25:08) How Cynthia became a world champion masters sprinter. (29:23) What Cynthia eats to support her neurotransmitters. (34:45) How beginners can build up to sprinting. (45:05) Which strength training exercises are best for sprinters. (45:57) How to improve your form and breathing while sprinting. (53:34) Items mentioned in this episode include: Organifi.com/Model - Use the coupon code MODEL for 20% off + free shipping! Fast Over 40 by Cynthia Monteleone - Check out Cynthia's book here! Connect with Cynthia Monteleone Website / Shop / Instagram Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Organifi. Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL at organifi.com/model.
Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity, and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin, and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response, and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection
Neil steps away from traditional business tactics to focus on the essential foundation of any successful venture: the health and well-being of the entrepreneur. He explores the concept of ‘The Fasting Miracle', specifically focusing on water fasting and its transformative effects on the body and mind. He breaks down the biological processes that occur during various stages of fasting, from the initial fed state to deep cellular repair and regeneration. By sharing his personal 21-day fasting experience and detailing the scientifically supported benefits, such as increased mental clarity, fat loss, and immune system rebooting, Neil provides a compelling case for fasting as a no-cost tool for tutors and coaches to optimise their performance and longevity. KEY TAKEAWAYS Maintaining good health is a critical business issue because it forms the foundation for everything a business owner does. Fasting triggers natural mechanisms like lipolysis (fat burning) and ketosis, where the body switches from burning glucose to burning stored fat and ketones for cleaner, steadier energy. Between 20 to 24 hours of fasting, the body initiates autophagy - a "self-eating" process where damaged cells and proteins are recycled into useful materials, reducing inflammation and the risk of degenerative diseases. Extended fasting (72+ hours) can eliminate old white blood cells and stimulate stem cell production to create a new, more efficient immune system. BEST MOMENTS "Health is the foundation on which everything we do is built. So staying healthy is a business issue." "Fasting isn't some brand new trendy fufu-dufu woo-woo fad. People have been doing it for centuries." "Autophagy is cellular cleanup and repair. The damaged proteins and organelles that are flapping around your body are broken down and recycled into useful stuff." "BDNF supports brain health and cognitive function. I've heard BDNF often called miracle grow for the brain, and that's what it does." "The longer I fasted, the better I felt. My mental sharpness increased like it's hard to explain. I just got sharper, faster." VALUABLE RESOURCES www.Neilcowmeadow.com info@neilcowmeadow.com HOST BIO Neil Cowmeadow is a maverick peripatetic guitar teacher from Telford with over 19 years' experience in the business of helping people. Learn how to start, grow and love your business with Neil's invaluable advice and tips without the buzzwords and BS! This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
Kylen Ribeiro shares essential ways to reduce your radiation exposure, explaining why holding your phone to your head, placing a laptop on your lap, and using some smart devices carry potential risks.
Your gut is doing far more than digesting food — it's constantly communicating with your brain, influencing mood, focus, stress levels, and emotional resilience. In this episode of the Craft Therapy Network Podcast, host Earl sits down with wellness researcher and creative healing advocate Mariam to unpack the science behind the gut-brain connection and the powerful role functional mushrooms play in mental wellness.The conversation breaks down how nearly 90% of serotonin is produced in the gut, how the vagus nerve acts as a communication highway between gut and brain, and why an imbalanced microbiome can contribute to anxiety, low mood, and mental fog. Mariam explains how mushroom beta-glucans act as prebiotics, feeding beneficial gut bacteria that reduce inflammation and support healthy neurotransmitter signaling.Listeners will learn how functional mushrooms like Lion's Mane, Reishi, Turkey Tail, and Cordyceps support focus, calm, immunity, and sustained energy — not through quick fixes, but by gently strengthening the gut-brain axis over time. The episode also explores emerging research linking mushroom compounds to BDNF production, synaptic health, and improved emotional resilience.Beyond science, this episode offers creative, practical ways to apply these insights through craft-based wellness practices. From gut-health meal journals and fermentation projects to mushroom-focused cooking nights and prebiotic recipe cards, Earl and Mariam show how creativity can reinforce mindful nourishment and long-term consistency.This episode is perfect for anyone curious about natural mental wellness, functional nutrition, and holistic approaches that support both the mind and body. It's a reminder that when you care for your gut with intention and creativity, your brain follows.
What if thousands of steps of gentle walking aren't giving you the brain protection you think they are? In this solo episode, I break down one of the most important exercise studies published in Nature Communications and what it means for your brain, longevity, and Alzheimer's risk. Tracking over 73,000 people for eight years using wearables, the findings are shocking: one minute of vigorous exercise is worth up to 10 minutes of moderate activity — not the outdated 2-to-1 rule. For diabetes prevention, it's nearly 10-to-1. For cardiovascular mortality, it's 8-to-1. And here's what no one is saying: every outcome measured — heart disease, diabetes, metabolic dysfunction — is an independent risk factor for Alzheimer's and dementia. I explain why vigorous exercise is so powerful for your brain: shear stress that strengthens blood vessels, lactate that triggers BDNF, muscle fiber recruitment that protects against falls and cognitive decline, and glucose regulation that defends against insulin resistance — a driver of neurodegeneration. Think vigorous exercise is out of reach? Good news: the study defines it as brisk stairs, carrying groceries, or playing actively with your kids. No gym required — just effort. Just 3–4 minutes of vigorous bursts per day can reduce all-cause mortality by 40% and cardiovascular events by nearly 50%. For women over 40, this is critical. Two-thirds of Alzheimer's cases are women, and perimenopause is a vulnerability window for the brain. Vigorous exercise can partially compensate for declining estrogen by improving glucose regulation, reducing inflammation, and protecting the brain in ways gentle movement cannot. *** Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/brain-code-yt Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Rho NutritionYou can get 20% off with the code NEURO at https://rhonutrition.com Function HealthVisit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. AquaTruGo to https://AquaTru.com now for 20% off using promo code NEURO. TimelineHead to https://www.timeline.com/neuro to get 20% off. Cure HydrationGet 20% off your first order at https://curehydration.com/neuro with code NEURO. *** I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed:00:00:00 Introduction: The Exercise Intensity Revolution 00:01:02 The Study That Changes Everything 00:04:50 The Flawed Foundation: Why Guidelines Were Wrong 00:06:50 The Real Numbers: 4 to 10 Times More Powerful 00:08:53 The Brain Connection No One Is Talking About 00:15:32 Mechanism 1: Shear Stress and Cerebral Blood Flow 00:17:38 Mechanism 2: Lactate and BDNF Production 00:19:25 Mechanism 3: Type 2 Muscle Fibers and Myokines 00:24:30 Mechanism 4: Glucose Regulation and Mitochondrial Health 00:28:18 VILPA: The 3-Minute Daily Game Changer 00:32:16 Women and Menopause: The Critical Window 00:35:19 Practical Protocols: What to Do Starting Today Learn more about your ad choices. Visit megaphone.fm/adchoices
Send us a text if you want to be on the Podcast & explain why!Ever feel the ground shift under a job you once loved? We sit down with a K–12 principal who built his identity around coaching kids, weathered the Paradise fire, and still found his purpose dissolving under politics, ego, and endless pushback. What follows is a candid look at walking away from a steady six-figure paycheck to pursue fitness, craft, and a life that feels honest again.We trace the throughline from early days lifting in Chico to leading schools where every decision meets resistance, and then to the spark of a new path: training, education reform from the outside, and programs that make movement central to learning. We talk openly about comfort as a trap, the fear of starting at zero, and the mindset shift that turns practice into momentum. If you're wrestling with a pivot, you'll hear a practical playbook: shadow great coaches, study daily, build a routine that stacks mobility, lifting, and focused learning, and have one meaningful industry conversation every day. It's career capital by design, not hope.There's a strong case for bridging education and fitness. PE gets sidelined, yet aerobic work boosts BDNF, sharpens attention, and primes the brain for class. With the right partnerships, schools can implement zero-period training, teacher wellness, and skill-based PE that kids actually believe in. This isn't about quick wins; it's about craft, clarity, and owning your trajectory. If you're choosing between safe and alive, this conversation will nudge you toward the path that compounds.If this resonates, follow the show, share it with someone stuck in a comfort loop, and leave a review with the bold move you're planning next. Keep showing up.Want to become a SUCCESSFUL personal trainer? SUF-CPT is the FASTEST growing personal training certification in the world! Want to ask us a question? Email info@showupfitness.com with the subject line PODCAST QUESTION to get your question answered live on the show! Website: https://www.showupfitness.com/Become a Successful Personal Trainer Book Vol. 2 (Amazon): https://a.co/d/1aoRnqANASM / ACE / ISSA study guide: https://www.showupfitness.com
Listen as host Amy Rodquist-Kodet, Health Coach with UK HR Health and Wellness, shares simple, research-backed practices to help steady your mood during the dark Winter months. Seasonal Affective Disorder (SAD) impacts millions each year, but small actions—light exposure, gentle movement and self-compassion—can make a meaningful difference. Amy says, “These practices aren't about fixing everything at once; they're about shifting your internal weather by a few degrees, building resilience over time.”Key Points:• Light: Morning light exposure is a powerful cue for your circadian rhythm. Even a short burst of brightness—like turning toward a window or a bright lamp—can support a more positive circadian rhythm.• Movement: Just 10 minutes of low-intensity movement can increase BDNF, a brain chemical tied to emotional stability and resilience. Think of gentle movements like rolling your shoulders or shifting in your seat.• Self-Compassion: Brief moments of self-kindness reduce stress and regulate the nervous system. Pairing a small action with a compassionate phrase—such as “I deserve steadiness and kindness”—makes the practice more powerful and sustainable.
In this episode of The Eric Bach Show, Eric breaks down seven specific foods that make losing stubborn belly and visceral fat easier—not by “magic,” but by improving insulin sensitivity, metabolism, gut health, inflammation, and hormone balance. You'll learn how to build meals that keep you full, support longevity, and help you look great naked… without starving yourself or living in the gym. Why the same foods that help you get leaner also protect your brain, mitochondria, DNA, and cardiovascular system as you age. The 7 Foods Eric Breaks DownCoffeeBoosts metabolic rate (roughly 3–11% in studies).Increases fat oxidation during exercise and can blunt appetite earlier in the day.Loaded with polyphenols like chlorogenic acid that support liver health, reduce oxidative stress, and may lower risk of neurodegenerative disease—as long as you're not turning it into a 500-calorie dessert drink. Lean Beef or Bison (93–95% lean)High-protein, nutrient-dense source with iron, zinc, B12, creatine, and some omega-3s (especially in grass-fed and bison).Higher protein = more thermogenesis, more satiety, better lean-mass retention in a deficit.CLA and omega-3s are linked to reductions in visceral fat and improved metabolic health. Wild BlueberriesImprove insulin sensitivity and help stabilize blood sugar, reducing cravings.High in fiber plus powerhouse antioxidants and polyphenols (anthocyanins) that support brain health, BDNF, and mitochondrial protection.Wild varieties can have 2–3x the antioxidant load of regular blueberries. Broccoli (and other crucifers)Ultra high volume, low-calorie, fiber-rich—great for appetite control and blood sugar stability.Rich in sulforaphane, which activates NRF2 (your body's “master antioxidant switch”) to support detoxification, lower inflammation, and protect DNA from damage. Greek Yogurt (2% or Non-Fat)High in protein to preserve muscle and support metabolism during fat loss.Probiotics support gut health, digestion, inflammation, and immune function.Fermented dairy is linked to better microbiome diversity and improved longevity markersLeafy Greens (Spinach, Kale, Arugula, Romaine, etc.)Low-calorie, high-volume, packed with folate, vitamin K, magnesium, nitrates, and antioxidants.Support insulin sensitivity, stress management, cardiovascular health, and nitric oxide (better blood flow, performance… and erections).Simple habit: a “big-ass salad” at dinner most nights. Wild-Caught SalmonElite combo of high-quality protein and omega-3 fats (EPA + DHA).Helps improve insulin sensitivity, lower systemic inflammation, and reduce cardiovascular risk by ~25–35% in some research.Supports brain function, mood, joint health, and telomere protection—huge for longevity and preserving leanness as you age. Big TakeawaysYou don't need “fat-burning foods”—you need fat-loss friendly foods that make a calorie deficit sustainable.Focus on foods that either had a face or came from the ground: protein + fiber + micronutrients beat pills, potions, and powders.Start by consistently adding 2–3 of these foods into your daily rotation, then build from there. Who This Episode Is ForAnyone struggling with stubborn belly fat despite “eating
We explore how movement reshapes the mind, builds self-trust, and reconnects you with your body's wisdom. Science, stories, and a guided practice show why intention and consistency—not intensity—unlock healing and growth.• reframing exercise beyond aesthetics toward agency • Sarah's story of confidence and identity change • brain chemistry and BDNF-driven neuroplasticity • movement as a tool for control and resilience • nervous system regulation and mindful presence • Marcus's rock climbing and rebuilding trust • somatic approaches for trauma and emotion release • debunking intensity myths and widening access • choosing modalities by desired feeling state • practical starting steps and consistent habits • guided mindful movement sequence for listeners • closing resources and community supportIf you'd enjoyed today's episode, I'd love for you to share it with your friends and family And if you're feeling generous, consider donating at the link provided in the description For more resources, tips, and updates, don't forget to visit our website at www.kore-fit.com and follow us on Instagram at KoreFitnessAZIlluminate Your World with Kore Candles!Kore Candle Company is a brand that specializes in creating unique and high-quality soy candles. Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showhttps://www.kore-fit.com
For decades, the topic of menopause has been overlooked, misunderstood, and undertreated. As more science emerges, more experts are sharing the truth about how women's brains and bodies shift during this important, transformative change. On today's show, you're going to learn about what actually happens during menopause and how to embrace and reclaim menopause. Today's guest, Dr. Mindy Pelz, is a New York Times bestselling author, functional health expert, and a leading voice in women's health, hormonal health, and aging. She's back on this episode of The Model Health Show to share the science and tangible takeaways from her new book, Age Like a Girl. In this interview, Dr. Mindy is sharing details about the hormonal shift that happens during menopause, and how women (and their families) can honor this transition. You're going to learn about how using lifestyle practices like weightlifting and fasting can help women balance hormones, eliminate brain fog, and boost their energy levels. You'll learn why there is so much misinformation and outdated narratives surrounding menopause, the science of neurochemical shifts, and how midlife can be a time to step into leadership and purpose. I hope you enjoy this interview with the one and only, Dr. Mindy Pelz! In this episode you'll discover: The meaning behind Dr. Mindy's new book, Age Like a Girl. (3:47) How the female brain rewires during menopause. (4:22) What the relational brain is and how it is impacted by hormones. (10:04) How environmental factors are changing the menstrual cycle. (13:40) What the grandmother hypothesis is. (22:21) The two main metabolic systems and how they work. (25:02) What estrogen's girl gang is. (26:28) How levels of insulin and glucose change during menopause. (27:42) The relationship between estrogen and dopamine. (32:59) Which supplement is a nutritional necessity for post-menopausal women. (42:01) How to naturally increase BDNF levels. (43:06) The importance of in-person knowledge sharing and storytelling. (46:27) What the toxic dump of menopause is. (58:48) Free or low-cost ways to naturally detoxify. (1:04:39) How men can support their partners through the process of menopause. (1:10:35) Items mentioned in this episode include: Thelumebox.com/model ß Get an exclusive $260 off your red light therapy device! Piquelife.com/model ß Get exclusive savings on bundles & subscriptions! Age Like a Girl by Dr. Mindy Pelz ß Preorder your copy of the book today! Connect with Dr. Mindy Pelz Website / Podcast / Facebook / Instagram / YouTube Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Lumebox and Pique. The LUMEBOX is clinically designed to deliver both red (660 nm) and near-infrared (850 nm) wavelengths in one sleek handheld device. Independently lab-tested for performance: more coverage, higher irradiance, and a greater effect. Enjoy an exclusive $260 off the premium LUMEBOX red light therapy system, designed to boost recovery, skin health, and overall vitality by using my exclusive link: thelumebox.com/model. Go to Piquelife.com/model for exclusive savings on bundles & subscriptions on cutting-edge solutions for your head-to-toe health and beauty transformation.
Trauma does not just live in your memories. It reshapes your brain. It can shrink your hippocampus, disrupt your prefrontal cortex, heighten your stress response, and leave you feeling stuck in survival mode. But the good news is this. Your brain is not fixed. It can heal. It can rewire. And one of the most powerful tools to rebuild a trauma-affected brain is movement.In this episode, I break down the neuroscience of how trauma changes the brain and how exercise can stimulate neuroplasticity, grow new brain cells, repair damaged pathways, and restore your ability to focus, learn, and feel in control again.You will discover why BDNF acts like fertilizer for your brain, how aerobic movement grows the hippocampus, why pairing exercise with mindfulness accelerates healing, and how to create a simple step-by-step plan to rebuild your brain even if you feel busy, stressed, or unmotivated.I also guide you through a seven day brain healing challenge you can start today and share how sleep, nutrition, connection, and lifelong learning work together to create the ultimate environment for recovery.This episode will show you how one small step can ignite big healing and longevity. Your brain can change at any age and any stage. And you can start rebuilding today./ / / Are you ready to take the next step on your brain optimization journey? / / /Choose your own adventure. Below are the best places to start:>>> Join Limitless Live 2025 Virtual Experience >>> Master Exceptional Memory Skills in 31 Days>>> Discover Your Unique KWIK BRAIN C.O.D.E To Activate Your GeniusTake your first step by choosing one of the options above, and you will find everything you need to ignite your brilliant brain and unlock your exceptional life, allowing you to achieve and surpass all of your personal and professional goals.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, Dr. Jockers reveals the simplest yet most powerful strategy to heal and protect your brain: intermittent fasting. By stabilizing blood sugar and reducing insulin levels, fasting supports mitochondrial health, which is crucial for maintaining brain function and preventing degeneration. You'll learn how brain degeneration isn't something that happens overnight, but rather a 30–40 year process that starts early, often in childhood. Dr. Jockers explains how poor metabolic health over time can silently damage the brain, leading to conditions like dementia and Alzheimer's. Finally, discover how intermittent fasting not only supports brain repair but also activates powerful neuroprotective mechanisms, including the production of BDNF, a critical factor for brain regeneration. It's a simple lifestyle shift with profound long-term effects on cognitive health. In This Episode: 00:00 Introduction to Intermittent Fasting and Brain Health 02:34 The Rise of Brain Degeneration 03:41 Benefits of Intermittent Fasting 09:28 Understanding Neuroinflammation 13:02 Preparing for Intermittent Fasting 15:44 Conclusion and Final Thoughts Struggling with digestion? Masszymes by BiOptimizers is the most potent digestive enzyme formula, featuring 300-500% more protease than most brands. This powerful blend breaks down proteins and other macronutrients, reducing bloating, inflammation, and indigestion. Try Masszymes risk-free with a 365-day money-back guarantee. Boost your digestion and feel your best—get yours today at bioptimizers.com/jockers and save 10% with promo code 'JOCKERS'! If you're serious about reducing your toxic load, I highly recommend upgrading to the P600 ceramic cookware. It's 100% free from Teflon, PFAS, and plastic coatings, ensuring a non-toxic cooking experience. Right now, you can get it for 50% off, plus an extra 20% off with the code SAFE20 at checkout! Don't miss this limited-time offer—head to chefsfoundry.com/jockers to claim your discount today! "You don't just wake up with dementia — it's a 30–40 year process silently damaging your brain long before symptoms appear." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Use code JOCKERS at bioptimizers.com/jockers to save 10% Use code Safe20 at chefsfoundry.com/jockers Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In this episode, Ben Azadi breaks down the science and real-life experience behind a 36-hour fast, explaining why this specific fasting window creates a powerful metabolic, hormonal, and cellular reset. Ben walks listeners through the hour-by-hour stages of the fast — from digestion, to fat burning, to deep autophagy — and explains how fasting transforms the body at every level. He covers increases in human growth hormone, gut repair, ketone production, mitochondrial upgrades, and the mental clarity that comes from elevated BDNF. He also answers the most common questions about long fasts:• What drinks or supplements break a fast• Whether women should modify fasting based on their cycle• How often to repeat a 36-hour fast• What symptoms are normal vs. concerning• Whether fasting impacts muscle• How to eat before and after a long fast for best results Ben also explains who should not attempt a 36-hour fast and how to break the fast without losing the benefits. He emphasizes that fasting is not starvation — it's a biological event designed for healing, fat loss, and metabolic restoration. FREE GUIDE: The World's Easiest Breakfast Diet - https://bit.ly/4puckHV
La dépression légère à modérée ne nécessite pas toujours un traitement médicamenteux. De nombreuses études montrent que certains remèdes naturels, bien choisis, peuvent agir efficacement sur l'humeur, l'énergie et la motivation. Sans remplacer un suivi médical, ces solutions offrent une alternative douce et scientifiquement validée.Le plus célèbre d'entre eux est sans doute le millepertuis (Hypericum perforatum). Cette plante agit sur la sérotonine, la dopamine et la noradrénaline — trois neurotransmetteurs essentiels à la régulation de l'humeur. Plusieurs méta-analyses ont montré que, pour les dépressions légères à modérées, le millepertuis est aussi efficace que certains antidépresseurs chimiques, tout en provoquant moins d'effets secondaires. Mais prudence : il interagit avec de nombreux médicaments (pilule contraceptive, anticoagulants, etc.) et doit être pris sous supervision médicale.Autre allié puissant : l'exercice physique régulier. Selon une étude publiée dans JAMA Psychiatry, 30 minutes d'activité physique cinq fois par semaine réduisent les symptômes dépressifs presque autant qu'un traitement médicamenteux. Le sport stimule la sécrétion d'endorphines, de dopamine et de BDNF, une protéine qui favorise la régénération des neurones. En clair, bouger modifie la chimie du cerveau de manière durable et positive.L'alimentation joue également un rôle clé. Les régimes riches en oméga-3 (présents dans le saumon, les sardines ou les graines de lin) sont associés à un risque plus faible de dépression. Ces acides gras participent au bon fonctionnement des membranes neuronales. De même, une carence en vitamine D, fréquente en hiver, est liée à une baisse de moral. Un apport suffisant — via le soleil, les œufs ou les suppléments — peut aider à rétablir l'équilibre.Parmi les autres pistes validées par la science : la méditation de pleine conscience, qui réduit les rechutes dépressives de près de 40 % selon une étude de l'Université d'Oxford, et la luminothérapie, particulièrement efficace contre la dépression saisonnière. S'exposer chaque matin à une lumière blanche intense pendant 30 minutes régule la mélatonine et stabilise l'humeur.Enfin, le sommeil reste un pilier souvent négligé : se coucher à heures régulières et éviter les écrans le soir améliore la production naturelle de sérotonine.En somme, les antidépresseurs naturels les plus efficaces — sport, lumière, plantes, alimentation, méditation — agissent tous sur un même levier : restaurer l'équilibre biologique du cerveau, sans effets secondaires lourds. Une preuve que la nature et nos habitudes peuvent, parfois, rivaliser avec la chimie. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Dr. Hoffman continues his conversation with Alan Frost, founder of Flava Naturals, and Dr. Joseph C. Maroon, MD, FACS, clinical professor and vice chairman of the Department of Neurological Surgery and Heindl Scholar in Neuroscience at the University of Pittsburgh Medical Center, and author of "The Science of Cocoa."
Alan Frost, founder of Flava Naturals, and Dr. Joseph C. Maroon, MD, FACS, clinical professor and vice chairman of the Department of Neurological Surgery and Heindl Scholar in Neuroscience at the University of Pittsburgh Medical Center, and author of "The Science of Cocoa," detail recent scientific findings on the cardiovascular and cognitive benefits of cocoa flavanols, the importance of sourcing and processing cocoa, and how cocoa can enhance athletic performance and brain health. The episode also covers the benefits of cocoa for skin health, fighting inflammation, and even mitigating some of the effects of sitting. Dr. Maroon elaborates on his protocols for concussion recovery, including the use of omega-3 fish oil, creatine, and CBD. The episode concludes with a discussion on how cocoa impacts mood and a special discount offer for Flava Naturals products. Just go to FlavaNaturals.com and use coupon code HOFFMAN20 for 20% off site-wide, plus get free shipping on all orders over $30.
Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.
On this episode of Vitality Radio, Jared dives deep into one of the most fascinating frontiers in functional nutrition—brain energy. He unpacks how ATP fuels your mind, why BDNF acts like “fertilizer for neurons,” and how lifestyle stressors, toxins, and poor sleep can dim your mental lightbulb. From there, he explores the natural tools that can reignite focus, memory, and long-term cognitive vitality. You'll hear how powerhouse nutrients can support mitochondrial performance, boost brain-derived neurotrophic factor, and promote sharper thinking—without the crash of caffeine or pharmaceuticals. Jared wraps up with three practical, results-driven protocols: one for focus and ADHD support, one for immediate memory and cognition, and one for long-term prevention of cognitive decline. Each stack can be customized to fit your individual goals so you can think clearer, focus longer, and age smarter—naturally.Brain Boosting Protocol CollectionShop the collection! Bundle and save - no code needed, just add to your cart to get:Buy 2 at 10% offBuy 3-4 at 15% offBuy 5+ at 25% offAdditional Information:Brain Boosting Protocol Blog Post#335: The Latest Research on Preventing and Reversing Dementia and Alzheimer's with Dr. Dale Bredesen#570: Liquid Yoga & Mind Fuel: Harnessing Mushrooms and Herbs for Focus and Calm#511: Unraveling NAD+ and NMN for Longevity and Anti-AgingVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
This episode dives deep into excitatory neurons—the brain's primary “go” signal—and their outsized role in the autistic phenotype. We explore how pyramidal neurons, powered by glutamate through AMPA and NMDA receptors, drive lightning-fast information transmission, synaptic hyperplasticity via BDNF, and elevated gamma oscillations (30–80 Hz) in V1, S1, and A1. This overactive excitatory push, paired with reduced parvalbumin and somatostatin inhibition, creates the well-documented E:I imbalance that fuels sensory hypersensitivity, one-trial learning, rigid memory encoding, repetitive behaviors, and the classic distal-connection timing mismatch from early sensory cortices to prefrontal regions.The autistic brain gets to the first two stops blazingly fast yet struggles to reach the final destination typical brains arrive at effortlessly.Inhibition Episodes: https://youtu.be/cjwbog7Rk4c?si=uSaLLNmS5EJLa_iHhttps://youtu.be/Oee4L7Vsj4E?si=Y5F2eVudCLhkxNw1 https://youtu.be/PBHVssvoQkM?si=A6SPedQi-Dt-DVO_E/I https://youtu.be/ETChjRQ0SzQ?si=yIFNovzldwSZRMeThttps://youtu.be/jl0xwjnyXII?si=dmk49CMQo3Uf17axDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Excitatory Neurons, Push-Pull System, Parvalbumin Deficiency03:30 E:I Imbalance, Sensory Hypersensitivity, Repetitive Behaviors07:00 Pyramidal Neurons, Glutamate, AMPA/NMDA Receptors10:30 Brain Regions: DLPFC, Anterior Insula, V1 S1 A114:00 Amygdala Misnomer, Low Road vs High Road, Emotional Hub18:30 Receptors: AMPA 1-5ms, NMDA 10-200ms, mGluR Modulatory22:00 Gamma Oscillations, BDNF Hyperplasticity, Sensory Overload25:30 Distal Connections, Point-A-to-Point-B Timing Mismatch29:00 BDNF Critical Period, One-Trial Learning, Rigid Memory32:30 TRN Dysfunction, Repetitive Behaviors, Corticostriatal Circuit34:30 Go-Signal vs Stop-Signal, Push-Pull Bowling Bumpers36:00 Rubenstein & Merzenich 2003, E:I Imbalance Foundation37:08 Daylight Computer Company, use "autism" for $50 discount39:32 Chroma Light Devices, use "autism" for 10% discount42:35 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
Send us a text Autistic mobility challenges? Dan Metcalfe (Total Balance Company creator, 70K+ transformations) shares recovery hacks: From stage paralysis (Andrew Lloyd Webber show) & 2018 brain death to full healing, his 7 pillars (oxygen/breathing, hydration, sleep, nourish nutrition, fun exercise, believe mindset, big challenges) build brain-body neuroplasticity—safe play over gym fear for conditions like Parkinson's/stroke/TBI/MS. For autistic/ND adults wobbly in transitions, parents preventing falls (#1 senior killer), or OTs fostering independence, this convo's your toolkit—no limits, just pathways. Timestamps: 0:00 - Intro: Dan's Paralysis-to-Pathways Journey 1:57 - Balance from Brain, Not Just Body 5:59 - Total Balance System for Autism 9:19 - Pillar 1: Oxygen & Breathing Basics 11:27 - Pillar 2: Hydration's Brain Impact 14:14 - Pillar 3: Sleep for Recovery 16:58 - Pillar 4: Nourish Over Eat Mindset 19:33 - Pillar 5: Fun Exercise Neurochemicals 22:49 - Pillar 6: Believe Over Hope Action 25:54 - Pillar 7: Big Challenges for Growth 30:42 - Mom's 84-Year-Old Ballet Success 34:38 - Evidence-Based Balance Classes Subscribe on Apple/Spotify for weekly neurodivergent adulting tools—rate/review if pillars sparked your step! Resources/books in notes. Squad, share w/ a wobbler (tag 'em below—let's steady up!). Merch: 'Dynamite' tees for balance days (Linktree in notes). #AutisticBalance #NeurodivergentMobility #7PillarsHealth #AdultingWithAutism #BTSNeurodivergent #PodMatch Struggling with autistic balance/mobility? Dan Metcalfe unpacks neuroplasticity for recovery: Paralyzed on stage (spine fracture), brain death crash—he rebuilt via brain-body focus (not muscles alone). 7 pillars: 1. Oxygen (deep breaths vs. shallow stress); 2. Hydration (75% dehydrated adults—brain uses 25% water/O2); 3. Sleep (detox/inflammation fight); 4. Nutrition ("nourish" mindset flips cravings); 5. Exercise (fun/dance releases serotonin/BDNF > gym); 6. Mindset ("believe" = action, hope = wait); 7. Challenges (Derby dreams inspire steps—MLK: Measure in trials). Total Balance System (rocking board/300 exercises) for safe play—Orange Grove autism success. From Adulting with Autism podcast: OT-aligned for ND transitions, falls prevention, independence. Tools for young adults/parents/OTs. Links: Full Episode: Buzzsprout/Apple/Spotify (subscribe!) Dan's Site: totalbalancecompany.com (free YouTube/classes/books) Instagram: @danmetcalfeofficial (DM for tips) Books: Get Your Balance Back & Born SuperHuman (Amazon) Merch: Linktree in notes ('Dynamite' tees for mobility motivation) Substack: N/A (focus on IG/FB for shares) Your reviews/shares amplify the squad—tag a balance-builder! #AutisticNeuroplasticity #BalanceTrainingAutism #Neurodivergent7Pillars #PodcastMobility #MentalHealthRecovery #UnmaskedBalance #ADHFallsPrevention #TraumaHealingAutism #ResilienceTools #EmpathySquad mfish: Organize. Simplify. Win Eco-friendly, high-quality tech tool to simplify school, work and life Find Your Fierce This Fall: Empowerment Shop now to support the show and join the Alliance—find your new favorite at the link in show notes. Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you. Support the show @adulting_autism adultingwithautism.podcast@outlook.com Hosted on Acast. See acast.com/privacy for more information.
Today's episode explores the role of inhibitory neurons & the Sonic Hedgehog (SHH) gene in shaping the Autistic phenotype, focusing on the excitation-inhibition imbalance that drives sensory hypersensitivity and cognitive challenges. Through a neuroscience lens, the episode connects these mechanisms to heightened gamma activity.Ben Ari Episode https://youtu.be/jo-ffwF9u0YParvalbumin Interneurons episode https://youtu.be/PBHVssvoQkM?si=t8WYGlcHcv7WiE-TVisual Thinking Part 1 https://youtu.be/XqQ8jCvWzYc?si=lffUEjGHjWj4mGOMNeurulation Part 1 https://youtu.be/gZdg9bX3Nuw?si=xvwtlz-p1hPHI8FADaylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismuse "autism" for 10% discount at Fig Tree Christian Golf Apparel & Accessories https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com00:00 - Autistic phenotype, excitation-inhibition imbalance, sensory hypersensitivity, cognitive deficits03:40 - Inhibitory neurons, GABA receptors, GABA-A, GABA-B, GABA-C, tonic inhibition07:24 - Tonic firing, burst firing, phasic firing, neural oscillations, sensory processing08:31 - Sonic Hedgehog gene, neural development, GABAergic identity, thalamic reticular nucleus (TRN)14:48 - Parvalbumin interneurons, fast-spiking, gamma oscillations, sensory gating, dorsolateral prefrontal cortex18:22 - Parvalbumin dysfunction, sensory hypersensitivity, visual cortex (V1), EI imbalance, brain-derived neurotrophic factor (BDNF)22:02 - Somatostatin interneurons, feedback inhibition, dendritic modulation, sensory adaptation, hippocampus25:43 - Vasoactive intestinal peptide (VIP) interneurons, disinhibition, pyramidal activity, attention, social processing29:30 - Calbindin interneurons, calretinin interneurons, dendritic inhibition, sensory processing, anterior insula33:15 - Purkinje cells, cerebellum, motor control, cognitive timing, cell loss in autism36:00 - Evolutionary perspective, parvalbium density, neural circuit stabilization, sensory-cognitive processing39:25 - Gamma activity, visual processing, retina, lateral geniculate nucleus, attention to detail, autistic self39:52 Daylight Computer Company, use "autism" for $50 discount42:13 Chroma Light Devices, use "autism" for 10% discount45:17 Reviews & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Conor H. Murray, a neuroscientist at UCLA whose research explores how psychedelics affect the brain. Find full show notes and links here: https://thethirdwave.co/podcast/episode-327/?ref=278 Conor shares insights from his placebo-controlled LSD microdosing study revealing measurable increases in neural complexity, suggesting unique neurological benefits even at sub-perceptual doses. He and Paul discuss what these findings mean for depression, addiction, and brain plasticity, as well as the future of citizen neuroscience through Conor's platform Psynautics. They also touch on his ongoing psilocybin study for cocaine use disorder and why low-dose research may hold keys to understanding consciousness itself. Interested in participating in Dr. Murray's Microdosing Study? Get 10% Off Your Enrollment! Use code WAVE3 to receive 10% off your study kit. https://www.psynautics.com/microdosing Conor Murray is a neuroscientist specializing in altered states of consciousness at UCLA. He is also the founder of Psynautics, the world's first citizen neuroscientist platform built for testing hypotheses related to altered states of mind and brain, from meditation to microdosing. His scientific expertise spans from the neurobiology of addiction to the effects of cannabis and psychedelics on the brain. Highlights How Dr. Murray entered psychedelic research by chance What LSD microdosing reveals about neural complexity The “sweet spot” around 13 micrograms for mental clarity Why placebo effects don't fully explain brain changes Microdosing vs macrodosing in neuroplastic outcomes BDNF, inflammation, and the mechanisms of healing Psilocybin's potential for cocaine use disorder How environment influences addiction and relapse The rise of citizen neuroscience and DIY EEG studies Where psychedelic science is headed next Episode Links Conor H. Murray, PhD Personal website Psynautics (Citizen Neuroscience Project) Psynautics Microdosing Study (Use code WAVE3 to receive 10% off your study kit) Episode Sponsors The Practitioner Certification Program by Third Wave's Psychedelic Coaching Institute. Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout
Season 14, episode 375 reviews episode 116 with Dr. John Ratey, exploring how exercise and lifestyle shape brain health and learning. The episode highlights Naperville's Zero Hour PE case study, explains how physical activity boosts attention and academic performance, and introduces BDNF (brain-derived neurotropic factor) as “miracle grow” for the brain. Practical takeaways include exercising before challenging work or school, prioritizing low-glucose nutrition, using hormesis (fasting, intense exercise, sauna) to increase resilience, and improving sleep and stress management to support cognitive health. On today's episode #375, we review our 2021 interview with Dr. John Ratey and will learn: ✔ How physical activity boosts attention and academic performance to improve results at school or in the workplace. ✔ What should we all understand about BDNF (brain-derived neurotropic factor) also known as “miracle grow” for the brain. ✔ How to build a faster, stronger, more resilient brain with exercise, nutrition, and with understanding hormesis. Welcome back to SEASON 14 of The Neuroscience Meets Social and Emotional Learning Podcast, where we connect the science-based evidence behind social and emotional learning and emotional intelligence training for improved well-being, achievement, productivity and results—using what I saw as the missing link (since we weren't taught this when we were growing up in school), the application of practical neuroscience. I'm Andrea Samadi, and seven years ago, launched this podcast with a question I had never truly asked myself before: (and that is) If productivity and results matter to us—and they do now more than ever—how exactly are we using our brain to make them happen? Most of us were never taught how to apply neuroscience to improve productivity, results, or well-being. About a decade ago, I became fascinated by the mind-brain-results connection—and how science can be applied to our everyday lives. That's why I've made it my mission to bring you the world's top experts—so together, we can explore the intersection of science and social-emotional learning. We'll break down complex ideas and turn them into practical strategies we can use every day for predictable, science-backed results. Episode 375: Featuring Dr. John Ratey For today's Episode 375, we continue with our review of past episodes as we make connections to prior learning with whatever it is that we are currently working on this year. I'll create a roadmap at the end of this season so this pathway will make sense to us (I hope!) as we piece together important parts of our success puzzle and begin to bring them to life. You'll notice that around the time of the pandemic, in 2020, our interviews took a turn towards health and wellness, and to stay on track, I created a framework of our Top 5 Health Staples on Episode 87[i], which eventually evolved into our Top 6 Health Staples. Today, we covering the first health staple of exercise, jumping to Episode 116[ii] on “The Revolutionary New Science of Exercise and the Brain” with best-selling author Dr. John Ratey. Dr. Ratey is also an Associate Clinical Professor of Psychiatry at Harvard Medical School and an internationally recognized expert in Neuropsychiatry. Dr. Ratey has published over 60 peer-reviewed articles and 11 books in 17 languages, including the groundbreaking ADHD “Driven to Distraction” series with Dr. Edward (Ned) Hallowell, MD. With the publication of “Spark: The Revolutionary New Science of Exercise and the Brain,” Dr. Ratey established himself as one of the world's foremost authorities on the brain-fitness connection. His most recent book, “Go Wild,” explores how we can achieve optimal physical and mental health by getting in touch with our caveman roots and how we can “re-wild” our lives.
In this episode, Angela sits down with Ulrich Dempfle, co-founder and CEO of CAROL Bike, to uncover the science and innovation behind one of the most time-efficient ways to boost VO₂ max, metabolic health, and brain function. Ulrich explains why VO₂ max is the most important marker for longevity, how it declines without training, and how short, AI-guided REHIT sprints boost mitochondria, BDNF (brain-derived neurotrophic factor), and cardiovascular fitness in just minutes. He also breaks down how Reduced-Exertion High-Intensity Interval Training (REHIT) works, why traditional zone 2 training doesn't work for everyone, and how gamification and real-time performance data make staying consistent easier than ever. What You'll Learn: Why VO₂ max is the strongest predictor of health and longevity How REHIT delivers major fitness gains in just minutes Why zone 2 training doesn't work for everyone How short, AI-guided sprints boost mitochondria and brain function Metabolic and cognitive benefits of REHIT How CAROL Bike personalises training to maximise VO₂ max TIMESTAMPS 00:00 Intro & The Importance of VO₂ Max 01:00 How VO₂ Max Declines and Why It Matters 04:22 Zone 2 Training Myths & Non-Responders 09:09 Mitochondria 101: Density vs. Efficiency 12:00 The Science Behind REHIT & CAROL Bike 19:09 Gamification, Dopamine & Workout Adherence 22:02 Lactate, BDNF & Brain Health Benefits 26:04 Insulin Sensitivity & Metabolic Effects 30:17 Efficient Weekly Training Structure 34:51 Afterburn Effect & Fat Oxidation Misconceptions 45:00 VO₂ Max Testing & Fitness Score Tracking 52:00 Peer-Reviewed Research & AI Personalisation 57:30 Real-World VO₂ Max Improvements 1:01:00 How to Get Started & Special Listener Offer VALUABLE RESOURCES Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: Exclusive discount for podcast listeners on Carol Bike - the bike that gets you fittest the fastest - click here WWW.CAROLBIKE.COM and use code ANGELA Hormone Harmony - go to LVLUPHEALTH.COM/ANGELA and use the code ANGELA at checkout for an exclusive 15% off ABOUT THE GUEST Ulrich Dempfle is the CEO and co-founder of CAROL Bike, the world's first Reduced Exertion HIIT (REHIT) exercise bike. Originally trained as a mechanical engineer in Germany, Ulrich began his career in the automotive industry before moving to the UK to pioneer AI in healthcare systems. After discovering REHIT through a BBC documentary, he partnered with leading exercise scientists to bring this lab-based protocol to the public. Today, Ulrich leads CAROL's product development, combining science, data, and technology to deliver the most time-efficient cardio workout. CAROL website: https://carolbike.com/ Find CAROL Bike on all platforms @theCAROLbike ABOUT THE HOST Angela Foster is an award-winning Nutritionist, Health & Performance Coach, Speaker, and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in Huff Post, Runners World, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️, a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and family without burning out. DISCLAIMER The High Performance Health Podcast is for general information purposes only and does not constitute professional or coaching advice, nor does it form a client relationship. The use of information on this podcast, or materials linked from this podcast, is at the user's own risk. Always seek advice from your medical doctor or healthcare professional before implementing any changes.
Order my new book Habits of High Performers here - www.thehabitbook.com What if your health span is shrinking because life got too comfortable?In this episode of Lead on Purpose, I sit down with Dr Paul Taylor to unpack Death by Comfort. We get practical about ultra-processed foods, protein-first meals, and movement habits that rewire your metabolism, brain, and daily energy. Simple, science-backed tools you can use today.We cover:What ultra-processed foods are, the NOVA system, and why supermarket breads and breakfast cereals often mislead.Protein at breakfast, 30 g targets, the 80/20 rule, shopping the perimeter, and keeping “treats” out of the house.Movement that changes your biology: myokines, BDNF, lactate-threshold bursts, movement snacks, and post-meal walks.Making it stick: match exercise to personality, use if-then rules, and model healthy habits for your kids.You will walk away with a clear plan to reduce UPFs, lift protein, move smarter, and build a home environment where better choices become automatic.Listen to Paul's podcast here - https://www.paultaylor.biz/podcastConnect with Paul here - https://www.linkedin.com/in/paultaylor1971/Grab a copy of Paul's book here - https://www.paultaylor.biz/booksLearn more about Paul here -https://www.paultaylor.bizIf you're interested in having me deliver a keynote or workshop for your team contact Caroline at caroline@jjlaughlin.comWebsite: https://www.jjlaughlin.com YouTube: https://www.youtube.com/channel/UC6GETJbxpgulYcYc6QAKLHA Facebook: https://www.facebook.com/JamesLaughlinOfficial Instagram: https://www.instagram.com/jameslaughlinofficial/ Apple Podcast: https://podcasts.apple.com/nz/podcast/life-on-purpose-with-james-laughlin/id1547874035 Spotify: https://open.spotify.com/show/3WBElxcvhCHtJWBac3nOlF?si=hotcGzHVRACeAx4GvybVOQ LinkedIn: https://www.linkedin.com/in/jameslaughlincoaching/James Laughlin is a High Performance Leadership Coach, Former 7-Time World Champion, Host of the Lead On Purpose Podcast and an Executive Coach to high performers and leaders. James is based in Christchurch, New Zealand.Send me a personal text message - If you're interested in booking me for a keynote or workshop, contact Caroline at caroline@jjlaughlin.comSupport the show
Upgrade your week in just 10 minutes with D(AI)ve Asprey's essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. This episode covers: • Apple Cider Vinegar Myth Busted A weight-loss study just got retracted. ACV will not melt fat, but it may blunt glucose spikes or ease digestion when diluted in water before carb-heavy meals. Skip the shots and protect your teeth. Source: https://www.sciencedaily.com/releases/2025/10/251001092216.htm • NMN Is Back The FDA reversal puts NMN back on shelves as a clean NAD precursor. Dave explains why quality, cycling, and stacking with anti-inflammatory strategies make the difference. Source: https://www.prnewswire.com/news-releases/renue-by-science-celebrates-fda-reversal-confirming-nmn-is-lawful-for-use-in-dietary-supplements-302573317.html • Poor Sleep Ages Your Brain Machine learning MRI studies show poor sleep makes your brain biologically older and raises dementia risk. Dave shares the three dials to track (deep sleep, REM, resting heart rate) and the three biggest levers to fix them. Source: https://www.sciencedaily.com/releases/2024/10/241023171543.htm • Psilocybin for Lasting Reset New research finds a single guided dose can unlock plasticity, ease pain patterns, and lift mood for weeks. Dave outlines safe protocols, integration steps, and why it is a strategic reset tool, not a party trick. Source: https://www.sciencedaily.com/releases/2025/06/250616040215.htm • AI Detects Cancer Earlier A new AI tool called DOLPHIN can find hidden genetic markers to flag cancer risk sooner. Pairing high tech scans with low tech terrain fixes like sleep, muscle, and insulin control is the prevention model that works. Source: https://www.sciencedaily.com/releases/2025/10/251001092206.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Apple cider vinegar, weight loss myths, NMN supplements, NAD precursors, cellular energy, sleep and dementia, brain aging, deep sleep optimization, REM sleep, psilocybin therapy, BDNF, neuroplasticity, pain relief, mood reset, AI cancer detection, early cancer screening, biohacking news, longevity science, Dave Asprey, Human Upgrade podcast Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 0:18 — Story 1: Apple Cider Vinegar and Weight Loss 1:49 — Story 2: NMN is Back in Supplements 3:31 — Story 3: Sleep and Brain Health 5:39 — Story 4: Psilocybin and Lasting Relief 7:49 — Story 5: AI Tool DOLPHIN for Early Cancer Signals 9:48 — Conclusion & Weekly Roundup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.