Podcasts about ssri

They are miserable about the stigma that antidepressants kill creativity, performance anxiety, and the struggle to stay productive without burning out.In this special episode of 'Misery Loves Mandy' for Mental Health Awareness Month, Mandy sits down with Macey Isaacs and Bijan Zarrabi, hosts of the podcast 'SSRI'M OK.' The discussion covers a wide range of topics, including mental health, depression, anxiety, and the stigmas associated with these conditions. Bijan, a psychiatrist, shares professional insights while the group also explores the intersection of mental health and creativity, how antidepressants affect people, and tips for achieving a balance between personal life and professional ambitions. Tune in for an engaging and informative conversation that also touches on personal anecdotes and the challenges of life in comedy.

In this episode of the Boost Your Biology podcast, Lucas Aoun interviews Miro Henzel, a biohacker and YouTuber, who shares his personal journey of overcoming hormonal issues and the importance of understanding the risks associated with supplements. They discuss the effects of finasteride and other DHT blockers, explore natural alternatives like Catuaba, and emphasize the significance of diet and lifestyle choices in optimizing testosterone levels. The conversation also touches on the role of coffee in hormonal health and the balance between enjoying life and maintaining health. In this conversation, Miro and Lucas delve into various aspects of health optimization, focusing on individual responses to coffee, the importance of quality in dietary fats, common mistakes in testosterone management, the role of DHT, managing prolactin levels, and addressing post-SSRI sexual dysfunction. They emphasize the significance of testing and understanding personal health needs, as well as the careful selection of supplements to enhance well-beingRelevant links:Miro Henzel's YouTube:https://www.youtube.com/@biohackingformenMiro's Email:mirohenzel@gmail.comCheck Out My Website For Coaching, Recommended Products and Much More:https://www.boostyourbiology.com/ Disclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program.Chapters00:00 Introduction to Biohacking and Personal Journey02:49 The Risks of Supplements and Hormonal Health05:11 Understanding Finasteride and Its Side Effects07:29 The Long-Term Effects of DHT Blockers10:12 Exploring Natural Alternatives: Catuaba and Other Herbs12:29 Key Supplements for Hormonal Health15:27 Dietary Considerations for Testosterone Optimization18:54 The Role of Coffee in Hormonal Health23:11 Balancing Enjoyment and Health24:55 Understanding Individual Responses to Coffee27:55 The Importance of Quality in Fats and Oils29:16 Common Mistakes in Testosterone Management32:56 The Role of DHT in Hormonal Health35:46 Managing Prolactin Levels for Better Health40:44 Addressing Post-SSRI Sexual Dysfunction45:36 Final Thoughts on Supplements and Health Hosted on Acast. See acast.com/privacy for more information.

 A tragedy made it more terrible by how preventable it was. It is urgent that this story be told and widely shared, given the tidal wave of depression and anxiety disorders that has washed over the United States in the wake of the COVID-19 pandemic, especially among young people. That tidal wave, combined with the overprescribing of powerful brain-altering medications and the widespread lack of awareness about the potentially lethal side effects of these drugs, is a prescription for disaster.This is a heartbreaking story of filicide, the potential risks of powerful antidepressants, and unforgiving justice with respect to crimes involving mental illness.He is the author of "Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins." https://www.amazon.com/Medication-Mental-Illness-Murder-Really/dp/1538199297http://www.yourlotandparcel.org

Today, we're chatting with Dr. Adam Urato, a fetal and maternal medicine specialist, to discuss the lack of informed consent given to pregnant women concerning certain medications they're taking, namely SSRI antidepressants. Dr. Urato tells us about the crucial role serotonin plays in fetal development and the negative effects that SSRI use in pregnancy can have on an unborn baby. We also discuss the increase in medical interventions in pregnancy in recent decades and how these interventions may not be as positive as they seem. And is the pharmaceutical industry to blame for doctors' lack of concern over SSRI use? This episode is brought to you by Olive, the app built for the MAHA movement. Download the Olive app now to see what toxins are hiding in your groceries. Share the Arrows 2025 is on October 11 in Dallas, Texas! Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠sharethearrows.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for tickets now! Buy Allie's new book, "Toxic Empathy: How Progressives Exploit Christian Compassion": ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/4COtBxy⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Timecodes: (01:50) Dr. Urato introduction (04:12) Over-intervention in pregnancy (15:27) Medication safety in pregnancy (29:07) Lack of medical concern (34:50) SSRI effects on fetal development (46:32) Doctors avoiding catastrophe (51:48) Postpartum SSRI use (58:34) What is the FDA's role?  (01:00:58) Dr. Urato's criticism of Makena --- Today's Sponsors: Seven Weeks — Experience the best coffee while supporting the pro-life movement with Seven Weeks Coffee; use code ALLIE at ⁠⁠https://www.sevenweekscoffee.com⁠⁠ to save up to 25% off your first order, plus your free gift! Good Ranchers — Go to https://GoodRanchers.com and subscribe to any of their boxes (but preferably the Allie Beth Stuckey Box) to get free bacon, ground beef, seed oil free chicken nuggets, or wild-caught salmon in every box for life. Plus, you'll get $40 off when you use code ALLIE at checkout. Hillsdale College — Hillsdale College is offering more than 40 free online courses they offer on History, Economics, Politics, Philosophy, and more, including their new course, "Understanding Capitalism," all available for FREE. Go to https://hillsdale.edu/relatable to enroll. A Faith Under Siege — Watch the explosive new film "A Faith Under Siege: Russia's Hidden War on Ukraine Christians," detailing the persecution of believers under Russia's expanding occupation. Go to faithundersiege.com to watch today. --- Related Episodes: Ep 821 | Why Antidepressants Don't Fix Depression | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-821-why-antidepressants-dont-fix-depression-guest/id1359249098?i=1000616890403 Ep 822 | The Big Money Behind Big Medicine | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-822-the-big-money-behind-big-medicine-guest-dr/id1359249098?i=1000617050991 Ep 1031 | Psychiatry Is Killing People | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-1031-psychiatry-is-killing-people-guest-dr-roger/id1359249098?i=1000661830317 Ep 650 | COVID Comeback, Depression Meds, & Alzheimer's Scandal | Guest: Dr. Jay Bhattacharya https://podcasts.apple.com/us/podcast/ep-650-covid-comeback-depression-meds-alzheimers-scandal/id1359249098?i=1000571375454 Ep 983 | What Doctors Aren't Telling You About Antidepressants | Guest: Brooke Siem https://podcasts.apple.com/us/podcast/ep-983-what-doctors-arent-telling-you-about-antidepressants/id1359249098?i=1000652056518 --- Buy Allie's book, You're Not Enough (& That's Okay): Escaping the Toxic Culture of Self-Love: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://alliebethstuckey.com/book⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Relatable merchandise – use promo code 'ALLIE10' for a discount: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://shop.blazemedia.com/collections/allie-stuckey Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the RWS Clinician's Corner, Margaret and Brendan explore the powerful connection between metabolic health and mental well-being, revealing why mental health isn't just about psychology—but also about our biology. Brendan breaks down his “three pillars” model for true mental wellness, walks us through nuanced approaches to lab testing, and explains why functional practitioners should be both evidence-based and deeply empathetic.    In this interview, we discuss:  Brendan's early experiences with mental health struggles and his challenges with the conventional psychiatric approaches  The importance of distinguishing between psycho-emotional issues and neurological/physiological health The role of objective biomarkers in validating client experiences, as well as the potential pitfalls of over-identification with laboratory findings  Recognizing when to refer clients to mental health professionals  Techniques for addressing emotionally charged or traumatic material during sessions The Clinician's Corner is brought to you by Restorative Wellness Solutions.  Follow us: https://www.instagram.com/restorativewellnesssolutions/ Note: This episode contains discussions about suicide, which may be distressing to some listeners. Please take care of yourself and feel free to pause or skip this episode if needed. If you, a client, or someone you know is struggling with thoughts of suicide, help is available. Here is a list of free, confidential resources available 24/7: 988 Suicide & Crisis Lifeline: Call or text 988, or chat online at 988lifeline.org      -Crisis Text Line: Text HOME to 741741 to connect with a trained counselor      -The Trevor Project (for LGBTQ+ youth): Call 1-866-488-7386 or text START to 678-678 These services are here to support you anytime, anywhere. Remember, reaching out for help is a sign of strength.   Connect with Brendan Vermeire: Website: www.metabolicsolutionsllc.com Instagram: https://www.instagram.com/the_holistic_savage/   Use the discount code RW25 to get Brendan's FMHP Workshop Series for FREE: https://holisticsavage.kartra.com/page/FMHP-workshop   Timestamps:  00:00 "Functional Mental Health Insights" 05:46 "Passion for Healing Amid Struggle" 10:01 "Bridging Science with Spiritual Fitness" 13:28 "Mind-Body Connection Explored" 16:31 Objective Biomarkers vs. Mysterious Diagnoses 19:22 Navigating Functional Medicine Challenges 21:09 Mycotoxin Tests: Limited Diagnostic Insight 27:17 Neuroinflammation and Immune Biomarkers 30:11 Rethinking Lab Test Investments 32:52 Clinical Intake and Lifestyle Assessment 36:29 "Effective Patient Engagement Strategies" 41:13 Essential Advice for Health Practitioners 43:21 Bridging Coaching and Functional Medicine 46:14 "Understanding Test Limitations in Health" 49:43 Functional Mental Health Training Program 52:24 "Listener Requests and Gratitude" Speaker bio: Brendan Vermeire is a Clinical Researcher, Functional Medicine Practitioner & Educator, passionate about teaching a root-cause approach to mental and metabolic Illness. He is the proud owner of the Metabolic Solutions Institute, home of the Functional Mental Health Practitioner Certificate Program.   Keywords: metabolic health, mental health, functional medicine, biomarkers, neurological health, psycho-emotional health, lab testing, suicidal ideation, root cause medicine, functional practitioners, SSRI, psychiatric drugs, metabolic markers, personal training, clinical research, depression, anxiety, neuroinflammation, microbiome, mindset, metabolic dysfunction, mold illness, mycotoxins, stool testing, coaching, motivational interviewing, C-reactive protein, neurofilament light chain, neurotransmitters, patient compliance   Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Autism, burnout, bug pinning, and bubblegum. We talk garden identity, TikTok spirals, anti-SSRI philosophy, and the stand-up stage as sensory battlefield. There's soy discourse, ceramic trivia, Play-Doh betrayal, and a lot of misophonia. Comedy gets dissected. So does voice. Also: the CIA is in the comments. Thank you all for Listening!  Follow Mikaela : https://linktr.ee/MiMikaela Follow Us: Podcast pages - https://linktr.ee/reydarpod https://www.instagram.com/reydarpodcast Rian Reyes - https://linktr.ee/rianreyes Josh the Producer - https://www.instagram.com/imjoshuabenjamin Support the podcast: Patreon - https://patreon.com/reydarpod Merch - https://www.etsy.com/shop/RiansMerch  Legacy Teas and Spices: https://legacyteasandspices.com Use code: rian20

While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as "the perfect life." She and her husband, David--a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance--had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as "the perfect life." She and her husband, David--a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance--had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as "the perfect life." She and her husband, David--a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance--had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/psychology

Dance has been outperforming SSRI's, anti-depressants, and all other forms of exercise in combatting depression symptoms in multiple studies. It makes sense to me that the combination of mental + physical coordination, the way it grounds you + forces you to be present, and the social aspect would have a profound effect on our health but it makes you wonder what other cultural practices and wisdom we've overlooked. SOURCES:The Dance vs. Depression Study: https://pmc.ncbi.nlm.nih.gov/articles/PMC10813489/ Another study: https://www.bmj.com/content/384/bmj-2023-075847 Articles on the topic:INDEPENDENT: https://www.the-independent.com/life-style/dance-best-exercise-depression-b2501113.html RELIEF MENTAL HEALTH: https://reliefmh.com/blog/dance-therapy-depression-anxiety/ DANCE MAG: https://dancemagazine.com/dancing-with-depression/#gsc.tab=0 HARVARD: https://hms.harvard.edu/news-events/publications-archive/brain/dancing-Donate to Palestinian Children's Relief Fund::www.pcrf.netDonate to Mutual Aid Funds: https://www.folxhealth.com/library/mutual-aid-fundsGET AN OCCASIONAL PERSONAL EMAIL FROM ME: www.makeyourdamnbedpodcast.comTUNE IN ON INSTAGRAM FOR COOL CONTENT: www.instagram.com/mydbpodcastOR BE A REAL GEM + TUNE IN ON PATREON: www.patreon.com/MYDBpodcastOR WATCH ON YOUTUBE: www.youtube.com/juliemerica Get bonus content on PatreonSupport this show http://supporter.acast.com/make-your-damn-bed. Hosted on Acast. See acast.com/privacy for more information.

Professor Jon Jureidini is a child psychiatrist who leads the Critical and Ethical Mental Health research group at Adelaide University in Australia. His forensic deconstruction of industry-sponsored clinical trials has exposed how pharmaceutical companies manipulate data, employ ghostwriters, and cultivate academic figureheads to create an illusion of scientific consensus around their products. Prof. Jureidini has revealed how medications prescribed to our most vulnerable populations—children and adolescents—gained approval based on studies that were fundamentally misrepresented in the scientific literature. In his groundbreaking book, 'The Illusion of Evidence-Based Medicine: Exposing the crisis of credibility in clinical research,' co-authored with Leemon McHenry, he systematically demonstrates how commercial interests have hijacked the evidence base that clinicians rely on, compromising patient care in the process. His work raises profound questions about the integrity of published research and challenges us to reconsider the foundations of modern medicine. Jureidini reveals shocking findings about the landmark 'Treatment of Adolescent Depression Study (TADS) study that's been used to justify prescribing antidepressants to teenagers—despite evidence showing a five-fold increase in suicidal events. With nearly 20% of adolescent girls now taking SSRIs, this conversation exposes the profit-driven deception that puts millions of developing brains at risk while pharmaceutical companies continue to thrive on what Jureidini calls "the illusion of evidence-based medicineChapters00:00 Introduction to the Crisis in Psychiatry02:20 The Illusion of Evidence-Based Medicine04:34 The TADS Study: A Closer Look10:47 Evaluating the TADS Study's Findings14:22 The Ethics of Informed Consent26:28 Risks and Alternatives in Treatment32:59 The Controversy of Antidepressant Prescriptions35:46 Ethical Concerns in Pharmaceutical Practices40:29 The Impact of Clinical Trials on Drug Approval47:08 Challenges in Psychiatric Research and Publication50:29 Restoring Trust in Scientific Integrity58:20 A Shift Towards Social Determinants of Mental Health RADICALLY GENUINE PODCASTDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here—-----------FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

Welcome to this Mad in America podcast. My name is Robert Whitaker, and I'm happy today to have the pleasure of speaking with Joanna Moncrieff. Dr. Moncrieff is a psychiatrist who works in the National Health Service in the United Kingdom. She is a Professor of Critical and Social Psychiatry at University College, London. In 1990 she co-founded the Critical Psychiatry Network, which today has about 400 psychiatrist members, about two-thirds of whom are in the United Kingdom. From my perspective, the Critical Psychiatry Network has been at the forefront of making a broad critique of the disease model of care. Without this network, I don't think that critique would be anywhere near as prominent or as sophisticated as it is today. Dr. Moncrieff is a prolific researcher and writer. Her books include De-Medicalizing Misery, The Bitterest Pills: The Troubling Story of Antipsychotic Drugs, and The Myth of the Chemical Cure. Her latest book is titled Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth. This book in many ways is a follow-up to her 2022 paper which looked at the serotonin story and concluded that there was no good evidence that a serotonergic deficiency was a primary cause of depression. It caused quite a furor within the media and in psychiatry. *** A full transcript of this interview is availabe here: https://www.madinamerica.com/2025/04/chemically-imbalanced-joanna-moncrieff-making-unmaking-serotonin-myth/  Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2025. Produced by James Moore https://www.jmaudio.org  

Navigating Medicine and Faith: A Conversation with Dr. Sharon Stoll In this episode, Dr. Sharon Stoll discusses her background growing up in a modern Orthodox Jewish community in Philadelphia, her journey to becoming a neuroimmunologist, and her professional experiences working at Yale and now in Philadelphia. The conversation touches on her approach to patient education, especially around COVID-19 and various medications, including GLP-1 agonists like Ozempic and SSRIs for mental health. Dr. Stoll also speaks about her role in JOWMA (Jewish Orthodox Women's Medical Association) and the importance of educating her community on medical issues.    The discussion covers her views on IVF, the ethical considerations of genetic selection, and the interplay of anxiety and genetic predispositions within the Ashkenazi Jewish community. Dr. Stoll shares personal anecdotes and insights into balancing professional and personal life, making this an in-depth and enlightening conversation.   00:00 Introduction and Background 01:19 Professional Journey and Achievements  02:08 Balancing Media and Medicine 03:48 Involvement with Jowma 05:40 Views on Vaccination 14:26 Discussion on SSRIs and Ozempic 28:16 Challenges in the Frum Community  34:38 Debunking Misconceptions About Diabetes 35:07 Educational Gaps and Community Efforts 36:43 Health Education in Schools 39:06 Challenges of Motherhood and Societal Expectations 43:43 Genetic Risks and Mental Health in Ashkenazi Jews 54:38 IVF, Genetic Selection, and Ethical Dilemmas  01:02:34 Concluding Thoughts and Personal Reflections   About Our Guest: Dr. Sharon Stoll is a board-certified neurologist, neuro-immunologist. She currently serves as Director of Neurology at Stoll Medical Group in Philadelphia. For the past 8 years she worked as assistant professor, in the department of neurology at Yale School of Medicine. She completed her neurology residency training at Thomas Jefferson University Hospital in Philadelphia and her Neuroimmunology fellowship at Yale New Haven Hospital. Dr. Stoll played an active role in academic development and continuing medical education. She currently serves on several steering committees and advisory boards. She has been published in numerous peer-reviewed journals and served as Principal Investigator on several clinical trials. Dr. Stoll has received numerous awards, including Top Neurologist, 40 under 40, the Rodney Bell teaching award, and is a national multiple sclerosis society grant recipient. Dr. Stoll is also a medical editor for Medscape and Healthline and previously worked as a medical editor for ABC News. She is also a medical commentator for several national and local news outlets, including ABC, NBC, and CBS News, and has been on a variety of shows, including “The Doctors”. She is an internationally renowned speaker and patient advocate.   https://www.drsharonstoll.com https://www.instagram.com/drsharonstoll/?hl=en https://www.jowma.org  

This week the guys return to discuss Senator Chris Van Hollen's trip to El Salvador that was telling in many ways about Kilmar Abrego Garcia and Trump's blatant human trafficking to CECOT, Trump just tells Putin to "stop it!" when it comes to the war in Ukraine, CEOs of big box stores tell Trump to knock off all the tariff nonsense, RFK Jr absolutely insane stances on school shootings, ailments he deems "exotic, and pushing to create an autism registry, Sarah Huckabee Sanders begs an unwilling Trump for federal support in Arkansas after 14 tornadoes hit the state, Department of Education plans to destroy people credit score for reasons, Trump administration says safety checks on milk costs too much...sorry guys, JD Vance killed the Pope, Pete Hegseth has yet another Signal screw up, and much more!Big TopicOur fucking Senator shows up for his constituentThere's another MD man who was sent to gulag erroneouslyHis example is rubbing offNews You NeedStop it guys, seriously! Just stop it!CEOs get Trump to back down on tariffs AGAIN!RFK Jr is fully out there saying really insane things about autism, SSRI drugs, and other disabilitiesAutism Registry?!!!!Governor Sarah Huckabee Sanders and Arkansas enter dreaded “Find Out” stageDefaulting on Student Loans, such much winningSafe drinking milk is basically communism, so we stopped doing that48 Hours Exec Producer quits; cites losing of independence as reasonIt's not all bad!Fast Corruption and Faster Screw-UpsPope chooses death after meeting JD Vance just onceTrump just straight up lies about where gas and food pricesRon DeSantis wife stole $10 million in medicaid moneyHegseth made a SEPARATE signal chat with friends and familyAnd he PURPOSEFULLY went around secure connectionsAnd he's having a makeup room installed in the PentagonCFPB eradicated; judge steps into stop it for nowWhat's Dumber, A Brick or A Republican?…but it might work for us!

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "Sleep and Seizures: Emerging Insights From AAN 2025," Nancy Foldvary-Schaefer, DO, director of the Sleep Disorders Center at Cleveland Clinic, reflected on key sleep-related topics presented at this year's AAN Annual Meeting. She highlighted the growing clinical interest in underrecognized conditions like idiopathic hypersomnia and narcolepsy, stressing the need for better awareness and earlier diagnosis. Foldvary-Schaefer also detailed the development of the Sleep by Cleveland Clinic mobile app, designed to improve screening for common sleep disorders with validated tools and real-time resources. Additionally, she discussed new findings on the prevalence of obstructive sleep apnea in adults with epilepsy, pointing to the importance of routine sleep screening in this population, regardless of seizure severity. Finally, she shared exploratory data on SSRI use and peri-ictal respiratory patterns in epilepsy, offering new perspectives on potential protective mechanisms tied to SUDEP risk. Looking for more neuromuscular discussion? Check out the NeurologyLive® Sleep disorders clinical focus page. Episode Breakdown: 1:00 – Key sleep topics discussed at AAN 2025 and the growing interest in hypersomnia 5:45 – Development and purpose of the SLEEP mobile app by Cleveland Clinic 10:35 – Findings on obstructive sleep apnea prevalence in adults with epilepsy 15:05 – Neurology News Minute 17:10 – The need for sleep disorder screening in epilepsy clinical trials 19:45 – Exploratory findings on SSRI use and respiratory patterns in patients with epilepsy The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Approves Pre-Filled Syringe Administration for FcRn Modulator Efgartigimod FDA Approves CT-132 as First Digital Therapeutic for Preventive Treatment of Episodic Migraine FDA Expands Diazepam Nasal Spray Indication to Treat Ages 2 to 5 Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Is it really possible to reverse lifelong autoimmune disease with one radical dietary change? Over 24 million Americans suffer from autoimmune conditions, and many more are told there's no cure. But what if that's not entirely true?  In this eye-opening episode, Dr. Josh Axe sits down with Mikhaila Peterson Fuller– popular health influencer, founder of the Lion Diet, and daughter of world-renowned psychologist Dr. Jordan Peterson– to explore how she put a lifetime of chronic illness, inflammation, depression, and joint replacements into remission by eating only one food.  From arthritis at age 7 to multiple joint surgeries and battling severe depression, Mikhaila's story is one of relentless suffering, radical transformation, and shocking revelations about how food affects the body and mind. Today, she shares how she used a meat-only diet to heal. In this episode, you'll discover:  How Mikhaila overcame autoimmune disease, childhood illness, and psychiatric misdiagnoses Why beef was the only food her body could tolerate– and how it changed everything How the Lion Diet works and why thousands of people are turning to it for relief from autoimmunity and inflammation.  The surprising role of SSRI withdrawal, chronic fatigue, and mismanaged infections in long-term illness The role that mold, gut health, and environmental toxins play in hidden chronic disease Which therapies, tools, and practices helped her reclaim her health beyond diet If you've struggled with symptoms that doctors can't explain, if you've tried “everything” and nothing's worked, or if you're simply curious about the cutting edge of autoimmune healing, this episode is for you. You'll walk away with real hope, fresh insight, and a deeper understanding of how the body, mind, and spirit are connected– and how to begin your healing journey today.  Tune in now and discover how one woman rewrote the rules of recovery and why her story might hold the key to yours.  #autoimmune #carnivore #draxe Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. ------  00:00 Mikhaila Peterson's Autoimmune Disease Story 07:23 The Carnivore Diet & Lion Diet 15:55 Consequences of & Conditions for Carnivore Diet 25:59 Danger of Medications 27:35 Healing Lifestyle Practices 30:10 How to Build Resilience  36:24 Mikhaila's Testimony  46:00 About Peterson Academy  50:49 Best Pieces of Advice ------  Follow Dr. Josh Axe Instagram Twitter Facebook Tik-Tok Website Follow Mikhaila Peterson Fuller Instagram Twitter Facebook YouTube ------  Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get: Holistic health news & life-hacks from a biblical world view Powerful free resources including classes, Q&As, and guides from Dr. Axe The latest episodes of The Dr. Josh Axe Show Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe  ------  Links:  Explore Peterson Academy for world-class, values-based courses taught by top professors → https://petersonacademy.com/  ------  Ads:  Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at https://beyondbloodwork.com/. 

TODAY ON THE ROBERT SCOTT BELL SHOW: SSRI Suicide Risks, Lisa Rooney, Ditch and Switch, Headache Remedies, Transformative Healing, Autism Rates Spike Nationally, James Lyons-Weiler, Popular Rationalism, Early Online Vaccine Censorship, School Exemption Laws Expand, Hospital Meals Home Delivery, Asclepias Tuberosa and MORE! https://robertscottbell.com/ssri-suicide-risks-lisa-rooney-ditch-and-switch-headache-remedies-transformative-healing-autism-rates-spike-nationally-james-lyons-weiler-popular-rationalism-early-online-vaccine-censorship-s/

Award-winning writer in advertising & higher educationEdward L. Jones III talks about his latest release “Meditation, Mental Illness& Murder-What Really Killed The Crespi Twins” chronicles David Crespi'sstruggle with insomnia & depression, the role SSRI antidepressants may haveplayed in the killings of his twin daughters and Kim's unimaginable journey oftrauma, suffering & eventual forgiveness while journeying into the darkheart of psychosis, the penal & mental health system and Big Pharma! Ed haswon more than 350 awards for his creativity & served as community columnistfor the Charlotte Observer currently living in Winston Salem, NC, and explainsthe side effects of SSRI with Big Pharma turning a blind eye to the matter andhaving long term effects on the family! Check out the amazing Edward L.  Jones III and his latest release on all majorplatforms and www.edwardleejones.comtoday! #edwardjones #edjones #author #awardwinningwriter #mediation #mentalcharlotteobserver#mentalillness #murder #crespitwins #davidcrespi #insomnia #depression #SSRI#antidepressants #bigpharma #charlotteobserver #winstonsalem #northcarolina #spreaker#iheartradio #spotify #applemusic #youtube #anchorfm #bitchute #rumble#mikewagner #themikewagnershow #mikewagneredwardljonesIII #themikewagnershowedwardljonesIII 

Award-winning writer in advertising & higher educationEdward L. Jones III talks about his latest release “Meditation, Mental Illness& Murder-What Really Killed The Crespi Twins” chronicles David Crespi'sstruggle with insomnia & depression, the role SSRI antidepressants may haveplayed in the killings of his twin daughters and Kim's unimaginable journey oftrauma, suffering & eventual forgiveness while journeying into the darkheart of psychosis, the penal & mental health system and Big Pharma! Ed haswon more than 350 awards for his creativity & served as community columnistfor the Charlotte Observer currently living in Winston Salem, NC, and explainsthe side effects of SSRI with Big Pharma turning a blind eye to the matter andhaving long term effects on the family! Check out the amazing Edward L.  Jones III and his latest release on all majorplatforms and www.edwardleejones.comtoday! #edwardjones #edjones #author #awardwinningwriter #mediation #mentalcharlotteobserver#mentalillness #murder #crespitwins #davidcrespi #insomnia #depression #SSRI#antidepressants #bigpharma #charlotteobserver #winstonsalem #northcarolina #spreaker#iheartradio #spotify #applemusic #youtube #anchorfm #bitchute #rumble#mikewagner #themikewagnershow #mikewagneredwardljonesIII #themikewagnershowedwardljonesIII 

Award-winning writer in advertising & higher education Edward L. Jones III talks about his latest release “Meditation, Mental Illness & Murder-What Really Killed The Crespi Twins” chronicles David Crespi's struggle with insomnia & depression, the role SSRI antidepressants may have played in the killings of his twin daughters and Kim's unimaginable journey of trauma, suffering & eventual forgiveness while journeying into the dark heart of psychosis, the penal & mental health system and Big Pharma! Ed has won more than 350 awards for his creativity & served as community columnist for the Charlotte Observer currently living in Winston Salem, NC, and explains the side effects of SSRI with Big Pharma turning a blind eye to the matter and having long term effects on the family! Check out the amazing Edward L.  Jones III and his latest release on all major platforms and www.edwardleejones.com today! #edwardjones #edjones #author #awardwinningwriter #mediation #mentalcharlotteobserver #mentalillness #murder #crespitwins #davidcrespi #insomnia #depression #SSRI #antidepressants #bigpharma #charlotteobserver #winstonsalem #northcarolina #spreaker #iheartradio #spotify #applemusic #youtube #anchorfm #bitchute #rumble #mikewagner #themikewagnershow #mikewagneredwardljonesIII #themikewagnershowedwardljonesIII  Become a supporter of this podcast: https://www.spreaker.com/podcast/the-mike-wagner-show--3140147/support.

✨ Take the First Step To Balance Your Hormones Naturally With My FREE Hormone Symptom Profile Assessment: https://bit.ly/takemyhormonequiz   You're not crying in traffic because you're crazy. You're not snapping at your family because you're unstable. You're just living in a body that's shifting—and no one explained what that would feel like.   Let's be honest: Doctors are trained to treat clinical depression.   But most were never taught how perimenopause and menopause can impact our mood—or how symptoms of hormone imbalance like sadness, irritability, and emotional overwhelm can overlap with what looks like mental health issues.   Maybe you recently saw your GP, and she gave you a prescription for an SSRI without ever talking about your hormones. Or maybe you've been taking an antidepressant for a while and are wondering if it's actually helping.   If you've been medicating your mood but not seeing real healing, it's time for a deeper look.   In this episode, you will learn: ✔How hormone changes in midlife can mimic depression (and why your doctor may miss it) ✔ What SSRIs are actually designed to treat—and what they're not ✔ How symptoms like brain fog, exhaustion, and night sweats are related to emotional health ✔ What no one's asking in your doctor's office—but absolutely should ✔ The 3 red flags that your prescription might be masking a hormone imbalance ✔ Why your bloodwork might say “normal” even when everything feels off ✔ The sneaky difference between coping and healing (and how to tell which you're doing) ✔ What to ask before refilling your SSRI (that your doctor may have missed the first time)   Plus, learn how Hormone Symptom Profiling can uncover the hormonal root cause of your emotional symptoms.   If you've ever said, “I just don't feel like me anymore” or are wondering why you're still struggling…even though you're on an antidepressant…this episode is for you! — Next Steps:   Take the First Step To Balance Your Hormones With My FREE Hormone Symptom Profile Assessment!: https://bit.ly/takemyhormonequiz Master Your Midlife Hormones In Less Than 90 Days. Apply To Work With Me: bit.ly/fixmyhormonesnow Episodes Mentioned: EP 1 | How Do I Know If I'm In Perimenopause?: https://pod.fo/e/2297e9 EP 40 | Feeling Anxious? The REAL Reason Your SSRI Isn't Working, Plus 5 Tips to Reduce Anxiety Naturally [Perimenopausal Symptoms: From A-Z]: https://pod.fo/e/26f30e Connect With Me:   Never Miss A Single Episode! Become An AYTM Podcast Insider: https://areyoutheremidlife.com/   Have a Question About Hormone Balance? Get It Answered On The Podcast: https://www.speakpipe.com/AreYouThereMidlife   Email Me: monica@monicalanetopete.com   *Disclaimer: Information provided in this podcast is for educational and entertainment purposes only. The information is not intended or implied to supplement or replace professional medical treatment, advice, and/or diagnosis. I share the strategies that have worked for me and you are advised to do your own research and speak to your medical provider for care.

Dr. McFillin shares a personal health experiment that accidentally exposed a troubling reality about our medical system. What began as self-experimentation led to a shocking revelation about how patients can be misdiagnosed, medicated, and misled.Dr. McFillin pulls back the curtain on the pharmaceutical establishment's questionable claims and the corporate takeover of medicine that has transformed doctors from healers into protocol followers. He reveals a disturbing conversation with a client that demonstrates just how far medical ethics have eroded. This eye-opening discussion challenges everything you've been told about "safe and effective" treatments and offers practical strategies to protect yourself and your family in a system that may not have your best interests at heart. A must-listen for anyone who's ever felt dismissed, manipulated, or harmed by modern healthcare.Joint Statement on Federal Concerns About Psychotropic Medication SafetyLawsuit against FDA over SSRI warning label is thrown outDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here—-----------FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

In this powerful and honest episode of The Penis Project Podcast, Melissa Hadley Barrett speaks with Dave and his partner Jen about their journey dealing with premature ejaculation (PE) — a common but often misunderstood sexual health condition affecting many men and couples.  Dave opens up about his experience living with PE since adolescence, the impact it had on his confidence and relationship, and how alcohol became a coping mechanism. With courage and persistence, Dave eventually found the right healthcare support, the right SSRI medication, and a path forward that improved both his sexual function and emotional connection with his partner.  Together, Melissa, Dave and Jen dive deep into the emotional, psychological, and physical sides of premature ejaculation — offering valuable insights for men, couples, and practitioners alike.  In This Episode, We Cover:  What premature ejaculation really is – and what it isn't  The difference between primary and secondary PE  Why many men are misinformed or dismissed by health professionals  The impact of PE on relationships, communication, and self-esteem  Dave's journey through trial-and-error with various SSRIs: Priligy (Dapoxetine), Paroxetine, Fluoxetine and Escitalopram (Lexapro)  The hidden cost of online treatment platforms – and why cheaper, more ethical options exist  How the right treatment changed everything – from sex drive to emotional closeness  Jen's reflections as a partner and the importance of support, understanding and touch  How couples can reconnect through small changes, time together, and deeper conversations  Melissa's recommendation: Sanctuary of Ananda for Tantra-based relationship connection workshops  Key Takeaways:    Premature ejaculation is more common than you think – and it's treatable  Not all SSRIs are the same. Personalised treatment matters.  The emotional and relational impacts of PE are real – and deserve attention  There's no shame in asking for help. Support is available, affordable, and effective.  Sexual health is about more than performance – it's about connection, confidence, and communication  Expert Insight from Melissa Hadley Barrett:  “If PE is affecting your confidence, relationship or sex life – there is help. You don't need to suffer in silence. With the right support, treatment can be simple, effective, and affordable.”  Resources & Links:  Book a telehealth consult with our sexual health nurse practitioners at Restorative Health Clinic  Learn more about Sanctuary of Ananda – Tantra and connection workshops for couples  Listen to Cam Fraser's podcast on modern masculinity and sexual wellness  For more information check out our websites www.rshealth.com.au , www.makehardeasy.com.au and www.melissahadleybarrett.com.au   Listen & Subscribe  If you found this episode helpful, don't forget to subscribe, rate, and review the podcast! Your feedback helps us continue bringing important conversations to light. Search for The Penis Project Podcast on Spotify, Apple Podcasts, or your favourite podcast app.  Connect With Us  Have questions or want to share your story?  Email: admin@melissahadleybarrett.com  Website: www.rshealth.com.au  Websites:  https://rshealth.com.au/  All genders  https://makehardeasy.com.au   https://melissahadleybarrett.com   http://www.menshealthphysiotherapy.com.au/  http://prost.com.au/     Facebook:  https://m.facebook.com/p/Melissa-Hadley-Barrett-100085237672685/  https://www.facebook.com/profile.php?id=100085146627814    Instagram:  https://www.instagram.com/melissahadleybarrett/  https://www.instagram.com/restorativehealth.clinic/  TikTok: @melissahadleybarrett  YouTube: Melissa Hadley Barrett  Linkedin:  https://www.linkedin.com/in/melissa-hadley-barrett/   TEDX  https://www.youtube.com/watch?v=IjHj1YTmLoA 

Feeling anxious? One of the best ways to address anxiety can be through improving the health of your gut microbiome - which produces serotonin (think SSRI antidepressants) and GABA (think Valium). Improving gut health is something I am passionate about - and I'm delighted @tim.spector could join me on A New Way of Being https://www.simonmundie.com/restore-balance-mini-course https://www.simonmundie.com/restore-balance-coaching My links: Book: https://www.simonmundie.com/book YouTube: https://tinyurl.com/YouTubeSimonMundie Website: simonmundie.com Substack Newsletter: https://simonmundie.substack.com/ Instagram: https://www.instagram.com/simonmundie/ Info@simonmundie.com Learn more about your ad choices. Visit megaphone.fm/adchoices

FAIR News Weekly | 4/4/25

Adam and Drew open the show discussing the change in Adam's flora and fauna and how that has impacted his ability to fart with impunity anytime he wants. They also talk about a letter Adam got from one of his former employees and take listener calls on SSRI's impacting weight and the details involved in getting a vasectomy.

“Fifteen or 16 percent of the population [is] now taking antidepressants … When they've gone out and asked people who actually use these medications whether they're experiencing sexual dysfunction, approximately 60 percent of people will [affirm] it.”Dr. Josef Witt-Doerring is a board certified psychiatrist, former FDA medical officer, and director of the Taper Clinic. He treats patients suffering from post-SSRI sexual dysfunction (PSSD), and protracted withdrawal—two conditions becoming more common, and in some cases permanent, in people who have stopped taking antidepressants.“SSRIs and antidepressants are really popular drugs. Some people just don't want to believe that they could potentially cause something so catastrophic,” he says. “We should only be using these medications after we've done everything else.”In this episode, we discuss how patients can safely discontinue psychiatric medications and regain control of their mental health, and why there needs to be more awareness about conditions that arise after people stop taking their drugs.“What I saw going through all of that ... as a drug safety officer ... was essentially that we really were practicing outside of what the psychiatric clinical trials and the evidence showed,” says Witt-Doerring. “Doctors have been led astray about the drugs to the point where they overestimate the benefits and minimize the harm.”Views expressed in this video are opinions of the host and the guest, and do not necessarily reflect the views of The Epoch Times.

Matt Crawford speaks with author Edward L. Jones III about his book, Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins. While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as “the perfect life.” She and her husband, David—a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance—had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes. In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries. Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma.

In this episode, we're joined by Dr. Susan Payrovi. Together, we'll explore the healing power of dance - and specifically, utilizing dance as a healing tool for depression. We'll review a recent article sharing a comprehensive study about depression, and take a deep dive into the results to learn about the effectiveness of dance and a handful of other exercise types. We'll also compare those with the results of using SSRI's, the standard pharmaceutical family of medications prescribed to treat depression. Tune in to learn the history behind Dr. Payrovi's virtual dance studio creation - The Myelin Room - and receive a personal invitation from Dr. Payrovi to attend her next virtual Myelin Room experience next month. DrSusanPayrovi.com for more information and to sign up! Take a listen and explore what's possible for you!! patreon.com/MSFlock

This episode is highly recommended!Yes folks, here on Rick Flynn Presents podcast, we are rolling out the red carpet for author EDWARD L. JONES III as he unveils the heartbreaking true story of the Crespi family and the struggles they were forced to endure.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma.Contact the author: www.edwardleejones.com

Modern Wisdom Key Takeaways  The insurance companies and big pharma complex monetize chronic diseaseThey benefit if more Americans are chronically ill because it means more prescriptions and therefore more kickbacks and rebates Approximately 30% of the revenue generated from opioid abuse in America went to the big five insurance companies The insurance companies are incentivized to put you on drugs!About 60% of United Healthcare's annual revenue – $361 billion in 2024 – comes from prescription drugs via an entity called a pharmacy benefit manager The average American is on 4+ prescription drugs SSRIs are one of the most worrisome drugs of the day: A metaanalysis of over 75 studies revealed that 85% of the efficacy of an SSRI was related to placebo On a 52-point depression scale, SSRIs differentiate from placebo by 1-2 points The healthcare system is not broken; it is rigged, and the American taxpayer is the one footing the bill “Prescribing a GLP-1 without talking about diet, lifestyle, and nutrition is like brushing your teeth while eating Oreos.” – Brigham Buhler Behind age and smoking, the third biggest cause of chronic disease is metabolic diseaseTo fix the healthcare system, fixing metabolic health should be our primary focusWe have built an entire healthcare industry of siloed experts, but the body is one organism; we should adopt a more holistic approach to treatment Using AI to build a better system: We will use algorithmic-based medicine to take a proactive and predictive approach to medicine, which will reduce the onset of chronic disease immediately upon recognition Faster iteration phases between detection and intervention will improve our health Read the full notes @ podcastnotes.orgBrigham Buhler is a healthcare entrepreneur, founder and CEO of Ways2Well, and co-founder of ReviveRx Pharmacy. American healthcare stands apart from any other system in the world. While some argue it has the potential to be the best, for many, it feels like the worst. Sky-high costs, an overreliance on prescriptions, and systemic inefficiencies suggest something is deeply broken. Why is this the case, and what can be done to fix it? Expect to learn what the number one reason for bankruptcy in America is, what the average state of health is for the average American and how it compares to the rest of the world, why so many American's are on Pharmaceutical drugs, what drugs Americans are taking that are causing the most damage, what is happening with the Food industry's corporate capture of food, how much of an impact RFK can really have on changing the pharmaceutical and food system, the simple changes that can improve American healthcare and much more… Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a Free Sample Pack of all LMNT Flavours with your first purchase at https://drinklmnt.com/modernwisdom Get $350 off the Pod 4 Ultra at https://eightsleep.com/modernwisdom (use code MODERNWISDOM) Get a 20% discount on Nomatic's amazing luggage at https://nomatic.com/modernwisdom Get the best bloodwork analysis in America at https://functionhealth.com/modernwisdom Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, show themselves in four distinct personality types. These methylation personality types, methylation archetypes, or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Activist and The Artist are very closely linked. Neither are terribly ambitious or driven, except in the thing that matters to them, whether it's their art, their job (which might not be art or activism), or the cause that matters to them. Both tend to have fewer allergic-type reactions but are more likely to have food sensitivities or chemical sensitivities. Things like wheat sensitivity, soy sensitivity, rashes with the wrong laundry detergent, or headaches after smelling perfume. Both of these personalities thrive on leftovers and fermented foods, even though leftovers and fermented foods are high in histamine.These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin aren't great for these groups. Likewise, the major methyl donors like SAMe, TMG, and DMG are typically not well tolerated by the artist and the activist. Conversely, these groups usually do very well with good sources of folate, like L-5MTHF, food-sourced folate, or folinic acid. Like all people with methylation imbalance, folic acid should not be taken because it can make methylation imbalances worse. Also, the benzodiazepine class of pharmaceuticals is usually well tolerated (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personality, take the quiz for free now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comIf you wish to support this channel by using affiliate links when you buy supplements and self-care that you want to buy anyway, I would appreciate it!Seeking Health: https://bit.ly/3afXYH4Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20Fullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

Cori suddenly pivots to surprise Nina with an unexpected interview about her lifelong mental health affliction and the medication she takes to manage it. What is the difference between grief and depression? Should you “feel your feelings” when your feelings are broken? What is serotonin? Which is a better theory of the brain: etchings or bike gears? We know very little about brains, which raises another question: can we talk to an SSRI expert?This is actually a pretty good discussion about depression and antidepressants, which is why we made it its own episode (the previous half is Episode 163: Cori's Boobs Break The Internet.)Link:Back on ‘Zac by Nina: https://blog.ninapaley.com/2025/02/08/back-on-zac/ Get full access to Heterodorx Podcast at heterodorx.substack.com/subscribe

Betsy and Ali dive into everything from dog rescue adventures and quirky SSRI-themed pet names—come here, Prozac!—to Lyme disease in dogs and unexpected pop culture throwbacks. With humor and heart, they navigate pet parenting, health updates, and the delightful chaos of everyday life.

256. Gut Health, Allergies, Inflammation and Proactive Solutions with Emily Macleod-Wolfe   1 Corinthians 6:20 CEV "God paid a great price for you. So use your body to honor God."   **Transcription Below**   Emily MacLeod Wolfe is a Nurse Practitioner wellness professional with a passion for helping individuals achieve their health goals in a holistic and practical way.   With 5 years of invaluable experience in the field, Emily has developed a deep understanding of the importance of a balanced lifestyle for a vibrant life.   Emily firmly believes in treating the whole person, not just the symptoms, and takes a comprehensive approach to healthcare. She learned these from her own personal experience of dealing with Hashimoto's thyroiditis and eczema and found the root causes to treat them naturally. She is passionate to help others with the personal knowledge and health freedom she has received.   By combining her medical expertise with a focus on nutrition, exercise, and mindfulness, she empowers her clients to take control of their health and make sustainable lifestyle changes.   With a warm and empathetic demeanor, Emily creates a safe and supportive environment where clients feel heard and understood. She works closely with each individual to develop personalized wellness plans that are tailored to their unique needs and circumstances. Whether you're looking to improve your physical fitness, manage stress, or simply lead a healthier life, Emily is dedicated to guiding, encouraging & supporting you on your wellness journey.   Emily's Website   Find a Functional Medicine Provider in Your Area   Questions and Topics We Cover: Will you define what it means when you refer to our "gut" and explain why our gut health is vitally important to our overall health? What lifestyle sets us up to have a healthier gut? If you had to simplify it and leave encouragement for each of these areas, what's a good starting point for something we can all start doing, stop doing, and continue doing?   Thank You to Our Sponsor: Dream, Build, Grow: A Female's Step-by-Step Guide for How to Start a Business by Francie Hinrichsen   Other Related Episodes on The Savvy Sauce Podcast: Being Intentional with our Health, Finances and Relationships with Elizabeth Dixon Simple Changes for Healthier Living with Leslie Sexton and Vasu Thorpe Pursuing Health, Not Vanity Before and After Childbearing with Blogger, Speaker, and Coach, Megan Dahlman Sustainable Health & Nutrition with Molly Pfleuderer and Ryan Parnham Rhythms of Renewal with Gabe and Rebekah Lyons Healthy Living with Dr. Tonya Khouri   Connect with us through The Savvy Sauce Website.   Gospel Scripture: (all NIV)   Romans 3:23 “for all have sinned and fall short of the glory of God,”   Romans 3:24 “and are justified freely by his grace through the redemption that came by Christ Jesus.”   Romans 3:25 (a) “God presented him as a sacrifice of atonement, through faith in his blood.”    Hebrews 9:22 (b) “without the shedding of blood there is no forgiveness.”    Romans 5:8 “But God demonstrates his own love for us in this: While we were still sinners, Christ died for us.”    Romans 5:11 “Not only is this so, but we also rejoice in God through our Lord Jesus Christ, through whom we have now received reconciliation.”    John 3:16 “For God so loved the world that he gave his one and only Son, that whoever believes in him shall not perish but have eternal life.”   Romans 10:9 “That if you confess with your mouth, “Jesus is Lord,” and believe in your heart that God raised him from the dead, you will be saved.”    Luke 15:10 says “In the same way, I tell you, there is rejoicing in the presence of the angels of God over one sinner who repents.”   Romans 8:1 “Therefore, there is now no condemnation for those who are in Christ Jesus”   Ephesians 1:13–14 “And you also were included in Christ when you heard the word of truth, the gospel of your salvation. Having believed, you were marked in him with a seal, the promised Holy Spirit, who is a deposit guaranteeing our inheritance until the redemption of those who are God's possession- to the praise of his glory.”   Ephesians 1:15–23 “For this reason, ever since I heard about your faith in the Lord Jesus and your love for all the saints, I have not stopped giving thanks for you, remembering you in my prayers. I keep asking that the God of our Lord Jesus Christ, the glorious Father, may give you the spirit of wisdom and revelation, so that you may know him better. I pray also that the eyes of your heart may be enlightened in order that you may know the hope to which he has called you, the riches of his glorious inheritance in the saints, and his incomparably great power for us who believe. That power is like the working of his mighty strength, which he exerted in Christ when he raised him from the dead and seated him at his right hand in the heavenly realms, far above all rule and authority, power and dominion, and every title that can be given, not only in the present age but also in the one to come. And God placed all things under his feet and appointed him to be head over everything for the church, which is his body, the fullness of him who fills everything in every way.”   Ephesians 2:8–10 “For it is by grace you have been saved, through faith – and this not from yourselves, it is the gift of God – not by works, so that no one can boast. For we are God‘s workmanship, created in Christ Jesus to do good works, which God prepared in advance for us to do.“   Ephesians 2:13 “But now in Christ Jesus you who once were far away have been brought near through the blood of Christ.“   Philippians 1:6 “being confident of this, that he who began a good work in you will carry it on to completion until the day of Christ Jesus.”   **Transcription**  Music: (0:00 – 0:08)   Laura Dugger: (0:09 – 1:15) Welcome to The Savvy Sauce, where we have practical chats for intentional living. I'm your host, Laura Duggar, and I'm so glad you're here.    If you are looking to start a business or side hustle, but you're not sure how to begin, I want to encourage you to pick up your copy of Dream, Build, Grow: A Female's Step-by-Step Guide for How to Start a Business. You can find it at foundingfemalesco.com.    Emily MacLeod-Wolfe is my kind and brilliant guest for today. She's a nurse practitioner, wellness professional, and she loves helping individuals achieve their health goals in a holistic and practical way.   Emily packs this conversation full of practical tips, and she sprinkles them throughout the entire episode. So, I hope you enjoy learning from her now. Here's our chat.   Welcome to The Savvy Sauce, Emily.    Emily Macleod-Wolfe: (1:16 – 1:20) Thank you so much for having me, Laura. I'm so excited to be here with you today.   Laura Dugger: (1:21 – 1:33) I'm thrilled for the opportunity to get to interview you. And just doing a little bit of research, I recognize you are such a gifted photographer. So, then what also led you to pursue a career in the health arena?   Emily Macleod-Wolfe: (1:34 - 5:05) Yes, thank you so much. So, first of all, with photography, from a very young age, I just started disappearing from family photos because I wanted to start taking them. And so I was blessed to have a couple of photography mentors, and I loved the ability to be able to capture someone and show them their worth and their beauty and give them maybe even an outside perspective of sometimes we can be so critical of ourselves and to be able to show someone their beauty and their worth in a photo, it was just incredible.   And so, I just have always, always been a people person and always loved really just showing people that. And then I started that and then it was actually my own health journey that ended up prompting me to go towards the health route. And so, I was diagnosed with Hashimoto's and eczema.   My skin, it was just I just became a bleeding open wound at one point where I literally couldn't I would cry myself to sleep. My mom would put mittens on my hands so that I would not scratch at night. We went to doctor after doctor and no one could figure out what was going on with all these health issues.   And they just kept prescribing medications and steroids, and it was it was making it worse. And there was a point where I went and did like a UV ray treatment and for my skin and my skin with the hydrocortisone had a reaction to the UV ray light. And then I went from like already looking really terrible, my skin falling off to like a burn patient.   And it was just horrible. And so from that point, I had prayed and felt prior that I was being called into medical missions. My parents are pastors.   And so, I really had a heart to do medical missions and be in ministry. And I thought immediately doctor. But then after I saw a nurse practitioner and she asked me all the questions that the doctors were not asking.   And she was like, what are you eating and what is your sleep like? What are your stress levels like? And we did allergy sensitivity testing.   And oh, my gosh, I was my gut was so imbalanced that I just could not eat anything. And I ate I was literally eating chicken and green beans for like nine months. But my gut reset because it was so inflamed and allergic to everything.   And we did certain things to calm the lining, heal the lining of the gut and my skin cleared. And it was incredible. That prompted me to go on this journey.   I was able to get off thyroid medication. The Lord healed my thyroid and prompted me into doing medical. And so I knew I wanted to go to Vanderbilt and I wanted to be a nurse practitioner and do the traditional training.   But go into holistic, integrative kind of have the best of both worlds, the traditional training. But then the functional medicine knowledge and then integrate the two. And so that's why my practice is called pure integrative health, because it's kind of blending both.   And I still do both. And I still do photography because I just love that creative aspect. And then I like the right and left brain.   It kind of gives a little change.   Laura Dugger: (5:05 - 5:27) I love that. That's such a good point. And I've learned so much from hearing you speak about these topics.   But it seems like people are starting to pay more attention to gut health in recent years. But will you just start baseline? Will you define what it means when you refer to our gut and explain why gut health is so vitally important to our overall health?   Emily Macleod-Wolfe: (5:28 - 8:59) Such a great question, Laura. Yes. So, first of all, the microbiome, which is it's our gut is essentially all the different intestines that colon, large intestine, small intestine, stomach.   That's the gut. Now, the lining of that, we've got billions of bacteria, trillions of bacteria in the gut. It's the only organ that is constantly communicating like through the vagus nerve.   There is continual communication called the set. The gut is called the second brain for a reason, because there is a constant stream of communication. The gut can actually send signals to the brain and then vice versa.   And so, it is the precursor to I mean, if we can heal the lining of the gut and if we can heal and balance out, when I say microbiome, it is the amount of good and bad bacteria that are all in in the gut. And so, we want a really healthy microbiome, which would be we want lots of strains of good bacteria outweighing the bad bacteria, very little to or just like not pathogenic, bad bacteria. So how and what do we do to kind of balance those things?   One thing is the good and bad bacteria. We want so many different strains of good bacteria. Now, studies have shown that over the last 100 years, the number of good back just even strains of different types of bacteria, the microbiome diversity has gone down dramatically.   And what could be causing that is the introduction of antibiotics, because since the introduction of antibiotics, there are far fewer. Good bacteria strains that are even possible to have and cultivate now, that's what keeps our immune system resilient is the abundance of many different types of good bacteria. And so, then when pathogenic bad bacteria viruses, we get sick, then the body has a strong enough immune system and the bacteria can just destroy the bad bacteria much quicker if we have that.   But just antibiotics, the chemicals in the food, toxins, even America's gluten, because it is genetically altered. It's not Italy's, but really good stuff. It's all affecting you.   Alcohol, the lining of the gut and weakening the immune system. Not why is this so important? Anyone that has autoimmune issues needs to be paying attention to the gut.   Hundred twenty percent because 90 percent of the immune system is made and synthesized in the gut. And so, then if the gut is sending out unhealthy signals, it will send those things. Rheumatoid arthritis, lupus, Hashimoto's thyroid disorder, just arthritis, anything with inflammation.   Yeah. So anyhow, all of those things, inflammation and it can be traced back to imbalances in the gut.   Laura Dugger: (9:00 - 9:23) And as you're sharing even what the gut is, just thinking food passes through all of those places as it gets processed. So, I'm assuming that I'm sure there's lifestyle factors as well. But is food the main reason beyond the antibiotics that are stripping it of the good bacteria?   Is that the main lifestyle change we can have is to eat a certain way?   Emily Macleod-Wolfe: (9:25 - 9:26) Great question.   Laura Dugger: (9:26 - 9:26) Yes.   Emily Macleod-Wolfe: (9:26 - 14:25) So food is the game changer because it is true. You are what you eat and the foods that we're eating, some of them are just the quality in the food. We could get organic, but they're showing now that sometimes we're not even getting the nutrients from the soil anymore.   They're not putting the right nutrients in the soil that the food was even grown in. So we're not getting the minerals and we're not absorbing things like B vitamins are not even being absorbed as well. Into the lining of the gut.   It's not even there to begin with in the foods or they are grown, but sent across the country and then gone to a grocery store. And they are no longer like three, four, five, six days after harvesting the mineral content in our foods drastically drops. And so.   As much as possible, I recommend getting to know your farmer, getting to know local farmers markets, places that can really go back and get food that was just freshly harvested, because we're going to increase the chances of getting cleaner, more nutrient dense foods that way. That's one thing. And the other is.   Sometimes we can be eating foods that are healthy that could actually be causing damage to the lining of our gut. And what I mean is some of you might have heard something called leaky gut. Well, what is that?   And like, where does it come from? It's in the lining of the colon, large and small intestine, and the stomach. There are these tight junctions of the cells that just keep everything in the digestive tract as properly.   We need food to stay in the digestive tract. We don't need it anywhere else in the body. And so, if there's a stressor to the body, then it can be from toxins, chemicals, food additives, preservatives, pesticides.   It can start to wear. And like I said, genetically altered gluten can wear away at the lining of the tight junctions. And all of a sudden there's holes in the lining of the intestine causing food particles to leak into the bloodstream, which what is the problem with that?   And that can contribute to food allergies and food sensitivities popping up like crazy. So, for example, an allergy usually is pretty immediate. Most people know their allergies because hives, throat closing, etc.   Sensitivities present up to 72 hours after eating a food. So we're talking joint pain, bloating, diarrhea, constipation. We're talking mood swings, depression, anxiety, brain fog, acne, psoriasis, eczema, all sorts of things.   And it can show up 72 hours after eating the food. So, all of a sudden playing a guessing game. Well, I ate eggs three days ago.   I was feeling fine. I ate eggs today and I feel bloated. Was it this or was it was it the broccoli or was it this?   And so then there's this and it could be continual exposure. Now there's more inflammation in the body because then that increases inflammation that can cause weight gain. And then there's foods leaking into the bloodstream.   It's going to weaken the immune system. So oftentimes with the intestinal permeability, we'll see heightened seasonal allergies are getting way worse. We'll see food sensitivities popping up like crazy.   We'll just see overall getting sick more frequently, all of those things as well. So I do highly recommend doing a food sensitivity test because, for example, I had a patient just last week who was trying to eat as healthy as she possibly could. And she was eating salmon, spinach and rice.   Well, we did a food sensitivity test and she came back to find out that salmon, spinach and rice were three of the top most foods causing inflammation, sensitivities and allergies in her body. And that was contributing to the inflammation and all the ways that she was she was feeling terrible, which is crazy because those are healthy, good foods. But the body, if there's if there's, you know, breaches in the lining of the gut, it doesn't start to recognize good food versus it's just it could pop up from eating the same food every single day or from from vaccines at a very young age that hijack the immune system and then or antibiotics from a very young age or.   Yeah, I'm spilling out lots of information.   Laura Dugger: (14:25 - 14:45) So helpful. I'm going to try and remember it. There's a few follow up questions.   Just thinking back to when you talked about eczema and skin issues, I think I've heard you say before that the skin is the last place where it shows up, where your imbalance and overall health will show up. Is that correct?   Emily Macleod-Wolfe: (14:45 - 17:06) That is correct. That is. Yes, exactly.   And so even a lot of skin issues are oftentimes an indicator of there's something deeper going on. Acne, psoriasis, eczema, what's going on? Eczema, psoriasis are autoimmune also.   So, looking at the gut is absolutely a game changer. I like a gut analysis. I will say with food sensitivity tests, they're not all created equal.   I have one that I do with my patients that checks for allergy, sensitivities and inflammation because some tests just test sensitivities. Some just test allergy and some will not.   There's none that really just test inflammation on their own. But how much better if you can look at all three and add them up? What foods could be causing inflammation, which is going to increase like almost every disease out there can be linked back to inflammation.   And then we can get inflammation down or be preventative. Maybe you're not feeling bad but just want to be on the preventative side. Great.   We want to reduce inflammation. And then the sensitivities and then the allergies. So IgE, IgG and then inflammation markers and the lining would be like the best way to look at everything.   And you want to pull them out, heal the lining of the gut best we can. There are foods, there's supplements and things depends on the person to exactly what is going on with their lining of their gut. But generally it can be repaired, which is great news.   It's like, is it forever? Is it like you guys? No, it's not.   It's just because the lining of the gut can regenerate in two or three weeks. So even two months of true two or three months of truly pulling out any foods that could be causing inflammation is just incredible because it gives the body the opportunity to finally heal. If it's not always continually having stressors coming at it from something that we can control.   Laura Dugger: (17:06 - 19:54) And now a brief message from our sponsor.    Are you starting a business or side hustle this year? There is a book I love, and I want to personally recommend because it takes the guesswork out of what to do next.   It's entitled Dream, Build, Grow: A Female's Step-by-Step Guide for How to Start a Business. And it's available at foundingfemalesco.com with over 300 pages of proven business tips and tricks. Dream, Build, Grow is perfect for anyone searching for how to start a business from the ground up. It is written by Francie Hinrichsen, who is an entrepreneur and my personal friend. 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Francie's book has already received over 20 five-star reviews on Amazon.   And readers say they loved the guidance on exactly how to gain clarity, save time, and build a business that works for the modern woman's lifestyle. Dream, Build, Grow: A Female's Step-by-Step Guide for How to Start a Business by Francie Hinrichsen provides realistic, achievable, and step-by-step guidance to finally start the business you've been dreaming about.   You can also save 10% when you use the code SAVVY at foundingfemalesco.com. Thanks for your sponsorship.    Laura Dugger: And I'd love to eventually unpack how some of these symptoms may present, whether that's insomnia or brain fog, low energy, all kinds of symptoms.   But first, I think you've given us a little glimpse of hope, so I want to run with that for a moment. So, eating whole, healthy, organic when possible foods that are locally sourced. Then you mentioned supplements and this testing.   So what are those proactive ways with both lifestyle and supplements? What do you generally recommend?   Emily Macleod-Wolfe: (19:54 - 27:50) I will say that foods in general that increase the microbiome diversity, which is good, the good bacteria that increase can be foods like kefirs and sauerkraut and kimchi, the fermented foods. Even sourdough bread is more easily digestible because it is fermented. And so some of those type foods that are rich in probiotics.   So probiotics, the good bacteria. But then there's prebiotics. I'm like, you know probiotics maybe.   But the prebiotics are the food for the probiotics. So we really want to feed the prebiotics so that the probiotics can multiply. So what are foods that are rich in prebiotic?   Chicory root, inulin, like the greenish like bananas, like not too ripe, but greenish, closer to green. Those are rich in prebiotics. Asparagus, onions, leeks, garlic.   Those are rich in prebiotics. And yeah, and so increasing some of those foods can help fuel the probiotics and help them multiply. But I and then as far as supplements go, a really good high quality probiotic is good.   I will say not all probiotics are made or created equally. And I would recommend you that you that are listening to consider seeing a holistic practitioner that can partner with you to do like, you know, a gut test and a food sensitivity test. And then when you do a gut analysis, it's not super fun.   It's a stool analysis. But it looks at the lining of the gut. Like we talked about, it looks at bacterial overgrowth, looks at bacterial undergrowth.   Like, is there something that's growing that's that used to be good, but now it's overgrown and it's bad bacteria that needs to be killed off? We can figure that out. And then we can look at is their yeast overgrown in the colon that can be contributing to skin issues and frequent infections, different things.   And then it looks at like not all of them, but like the top 20 parasites. So, we can know, okay, at least we know which ones most of us have some degree of parasites. Unfortunately, I don't like to think about it too much.   None of us do. But just need to come in from anywhere and just need to kind of get that flushed out. But I don't recommend people just starting on parasite cleanses without like fully knowing what else could be going on.   Sure, we can assume parasites and could cleanse. But if there's other bad bacteria that needs to be killed off that is you don't know about, that could worsen the situation. Or there's something called small intestinal bacterial overgrowth, SIBO.   And that can be caused by like someone who maybe errs towards constipation. And so the stool is sat in the stomach and then it's backing up into not just sitting in the colon, but backing up into the small intestine. Now, that can present as eating foods and immediately feeling like bloated or waking up feeling really bloated and full all the time and don't know why.   A lot of gas, a lot of problems with constipation or diarrhea. In those cases, that's why I say consider a holistic practitioner to kind of partner with you. In those cases, feeding the probiotics is not a good idea because that can be overgrowing small intestinal bacteria or bacteria that should not be continually to grow.   It can make you feel worse. So that's why there's like a yes, these are really good. But also you just it's good to know exactly where your gut is at because not everybody's microbiome and gut is the same.   There's different pieces like mine. I was very sick at a young age and I had a lot of antibiotics when I was at a young age. I know that weakened my immune system.   I think that made me more susceptible to having eczema at such a young age and then that worsening. And then when you have one autoimmune issue, it's likely that it can continue on to another one. So then I had Hashimoto's, which is another autoimmune disorder of the thyroid, but kind of snowballing all having to do with the immune system and the gut.   And so the more that we know the bigger picture and figure out, OK, what stressors have been here and what do we need to do about it, then definitely helps with that. Oh, and something about the with brain fog, anxiety and depression. I just want to touch on the mental effects of the gut because that is huge.   So one thing is a lot of people have been put on antidepressants like Lexapro, SSRI, selective serotonin reuptake inhibitors is what they're called. These antidepressants actually work more on the brain, which is not where we really want them to be working, because 80 to 90 percent of our serotonin receptors are in the gut. So dopamine, serotonin, melatonin, all of those really happy hormones that keep us happy and healthy.   There's a lot of people who haven't been diagnosed with anxiety, depression and been getting on these antidepressants and the antidepressant medications are not even working on the right organ. Isn't that crazy? So even in the gut, it's that's why a lot of the side effects of those medications are gut imbalances, because it's causing imbalances in the gut because of the gut brain access.   But really, what could we do if we can heal the lining of the gut? I have seen brain fog start to disappear because of bad bacteria or things that needed to be cleared out. I've seen more that you heal the gut, the more the thyroid gets balanced, the more that you heal the lining of the gut.   You can help heal the adrenals, which is just the way that body processes stress. That organ sits on top of the kidneys and vice versa, healing high cortisol stress hormones made in the adrenals. You could go back and heal the lining of the gut.   They're so interconnected, like each organ. And so anxiety, depression, ADHD. Oh, my goodness.   Kids with ADHD, I would say first thing, gut and food sensitivities. Check the food sensitivities, check the gut before going on ADHD medications, because there are likely mineral deficiencies that are happening, like B vitamins that are just not even being absorbed. D levels, different things that could be contributing to the problem that might not even be addressed.   Laura Dugger: (27:51 - 28:22) Well, and it sounds like the gut is the root cause of so many of these symptoms, but it's also very nuanced. And so seeing somebody like you would be ideal. Are there ever blanket statements that work?   I am thinking lifestyle, just how God created us to be outdoors and how that early morning light, that's kind of like a bio hack that helps all of these. Can you explain more about why that works or just any other things that would work for anyone?   Emily Macleod-Wolfe: (28:23 - 31:12) Yeah, that's great. So, one thing for sure is when you go outside first thing in the morning, you get 10, 15 minutes of that sunlight. The sunlight affects our vitamin D receptors and vitamin D is the precursor to melatonin.   So, melatonin is what helps us fall asleep and stay asleep. And so naturally increasing that melatonin so that it's funny, but you wake up that morning and then that night you're going to have a better sleep because of the morning sunlight. So, getting out even better is walking and moving because the more that we do exercise and that's going to increase the endorphins.   I know you've heard it before, but it's really true that if you exercise, it's going to increase serotonin and dopamine. It's going to give the body those surges of those things. And also in American culture, we're not moving enough and we're not tiring ourselves out physically.   I mean, we sure are tiring out the brain, but we're not tiring out the body. And so, there's this like discrepancy between an exhausted brain and then the body hasn't even had enough exercise. And then we try and go to bed and the brain keeps racing and the body's not as tired as it should be.   And so that's why also exercising daily and trying to get somewhere between that six thousand to seventy five hundred steps a day. That's like an hour of walking. I mean, you can walk around the house to that counts.   That's great. But just intentional walking and doing those things, that's going to help our mental health. And then weight bearing exercises are huge for prevention after the age of 30.   Twenties and the 20s is the decade in which well, teens and 20s, that is where we can build muscle. Lots of muscle can be built. And essentially after 30, it's just whatever muscle has been built will just continue to deteriorate until we die, which is unfortunate.   But that is why it is so, so, so important to do weight bearing exercise. It's not a doom and gloom. It's OK, let's be aware.   Yes, it's we're working against the natural decline in the muscles. That's why it's so important for prevention of osteoporosis, bone density, helping with sleep. So many things that weight bearing exercises one to three times.   If you need to start at one great work up to three times a week. Weight bearing exercises are incredible for men and women. It's good because it increases testosterone naturally.   Laura Dugger: (31:13 - 32:25) By now, I hope you've checked out our updated website, thesavvysauce.com, so that you can have access to all the additional freebies we are offering, including all of our previous articles and all of our previous episodes, which now include transcriptions. You will be equipped to have your own practical chats for intentional living when you read all the recommended questions in the articles or gain insight from expert guests and past episodes as you read through the transcriptions. Because many people have shared with us that they want to take notes on previous episodes or maybe their spouse prefers to read our conversations rather than listen to them.   We heard all of that and we now have provided transcripts for all our episodes. Just visit thesavvysauce.com. All of this is conveniently located under the tab Show Notes on our website. Happy reading.    It also makes me wonder just about hydration, sleep and stress management, too. How do those play into the brain gut connection and all of these symptoms?   Emily Macleod-Wolfe: (32:25 - 34:21) Yes. So, the sleep and stress, I will tell you that high levels of stress zap good bacteria from the lining of the gut. So, we can do the right probiotics.   You can do that gut test. You can do all those things. And then if there's high levels of stress continually exposing the body, it will contribute to just some bacteria will literally be zapped.   I've seen gut analysis where like the lactobacillus strains just fully gone. And that's what stress can do to our bodies. And that's going to weaken the immune system because we don't have all the different strains that we need to.   And so that makes us more susceptible for that. And then cortisol levels is melatonin and cortisol. Melatonin helps us.   It's a bell curve that helps us fall asleep and stay asleep. And then cortisol helps us stay awake. But if there's high levels of stress right before bed, then we're not going to be able to calm down, wind down and be able to rest properly.   So a lot of it with that lifestyle of our bodies need rhythm. We have to our bodies crave the balance of a rhythm and consistent schedule, because then the body can, you know, just little signals of I'm winding down. This is what I do.   My body needs extra help sometimes. And like, OK, it's winding down. I'm drinking some tea and taking a shower.   I'm meditating on the word. I'm not going to be looking at my screens too much because blue light really does signal the body to produce cortisol and stay awake. That's the blue light is the morning sunlight.   So, you don't want to be giving yourself screen time right before bed, because then that will be giving your body the signal to stay awake.   Laura Dugger: (34:22 - 35:01) That's fascinating, because I think there's even studies that show that blue light, I think approximately between 11 p.m. and 4 a.m., that exposure to that blue light can even eventually lead to, I think, more depression and anxiety. And just how you're talking, God did not rhythmically design us in that way. And we knew we wouldn't have time to fit everything in.   So, I can't wait to have you back to discuss hormones. But as we're winding down this conversation today, if you want to package it up, Emily, and just share an easy takeaway, what can we start, stop and continue doing with this information?   Emily Macleod-Wolfe: (35:02 - 37:56) So, I would say I'm going to start with the morning sunlight, starting with gratitude. And I am a huge proponent of spending time with the Lord in the morning. And the physical aspects to our emotions and physical, spiritual, emotional is also interconnected.   So, like thanking the Lord, spending time in the scripture, quoting those things, truly physically changes our body. Like the scripture that says, renew your mind daily, truly has an effect on the neurotransmitters in our brain. Because 90% of what we remember is from the day before.   And then 90% of our thoughts are usually negative. So, if we're continually going on a trajectory, we're going to go downhill. Unless we are continually renewing the mind in the morning to truth, to scripture, to like, what does God say about me?   What does God say about my health? All of those things. So, so, so important because we got to shift the 90% narrative.   And we've got to shift what we thought yesterday to today. So, I would say, pair it with a little 10 minute walk in the morning. And I would say, do eat for blood sugar management.   We can get into this more into the next episode, for sure, because we're going to smaller, more frequent meals. And I'll get into why that is so important, but not skipping out and going, you know, five, six, seven hours. That was the blood sugar and glucose is going to spike and crash.   And then that's going to affect the gut, the hormones, and we'll get into that 100%. But the morning sunlight, taking time to really meditate on truth and scripture in the morning, and then cutting out processed oils. I would say that would be a really big one that we can start cooking with.   Baking it, broiling it, grilling it, cooking with whole, real foods as best sourced as you can control from local, if you can. And having a good protein source and then fiber, like a vegetable and a fat for a meal or like a protein fiber and complex carb, like sweet potato, brown rice, quinoa, something like that. It's going to give you more longer energy and lasts a lot longer than just eating fruit or just eating a piece of toast or just drinking a glass of orange juice.   Which is typical for American culture, but that's just spiking sugar and crashing it.   Laura Dugger: (37:57 - 38:03) Okay, so that's the start and stop. Is there anything to continue?   Emily Macleod-Wolfe: (38:04 - 39:20) Anything to continue? Continue with the working out and just being consistent in that. Because also, the more that we walk, we do workouts, exercise, cardio, mixed with weights, it is bringing oxygen to our tissues.   And I don't think most people think of it in that way. Most of us know a handful of our friends and family members, loved ones that have passed from cancer or dealt with cancer before. But we need to remember that exercise increases oxygen to the tissues and cancer cannot survive in an oxygen rich environment.   So the more that we are pumping our bodies with oxygen and getting it to the tissues, it's going to prevent a lot of those cancers. And it's going to improve cardiovascular health. And just walking 6,000 to 7,000 steps a day can reduce the risk of dying between the ages of 20 and 65 by 40%.   Just the walking part or cardiovascular events. So, I would say keep walking.   Laura Dugger: (39:21 - 39:39) That's incredible. Well, you are such a wealth of knowledge. And as you shared, even getting these food sensitivities and allergy and inflammation tests, is that something that we can seek from you even if we're living in a different state?   Or would we have to find somebody local?   Emily Macleod-Wolfe: (39:40 - 40:28) Great question. Yes. So a couple of different options.   I have an option, opportunity that I can. I would need to see. I do see out of state patients.   I just have to see them for their first evaluation. And then after that, we can do like a hybrid telemedicine. See you back once a year, that kind of thing.   So that's definitely an option. And then obviously in person will just work. I can order testing, you know, even to wherever it is needed.   As far as finding a local practitioner in your current state, there is a website, ifm.org. And then you can go to that website and find a practitioner. If you prefer someone right there local, then you can do that too.   But there's options. Yeah.   Laura Dugger: (40:28 - 40:30) Wonderful. Okay. Well, we will.   Emily Macleod-Wolfe: (40:33 - 40:40) Pureintegrativehealth.com. That's the website, my website, that they can find out more information on how to become a patient if they were interested.   Laura Dugger: (40:41 - 40:49) Yeah. Wonderful. We'll link to those websites in the show notes for today's episode.   And I hope we all get a chance to meet you in person.   Emily Macleod-Wolfe: (40:50 - 40:50) Thank you.   Laura Dugger: (40:50 - 41:07) Wonderful. Well, Emily, I've enjoyed this time so much. But I do have one more question for you because we are called The Savvy Sauce because savvy is synonymous with practical knowledge.   And so, as my final question for you today, what is your Savvy Sauce?   Emily Macleod-Wolfe: (41:08 - 42:45) I would say that my Savvy Sauce for today is the importance of eating smaller, more frequent meals centered around protein and never having sugar by itself. Including fruit, including carbs, always pairing it with protein and the order in which we eat a meal can affect glucose. Because if we can get the blood sugar controlled, it came out this year, type 3 diabetes, Alzheimer's, type 3 diabetes, sugar in the brain.   So we can prevent Alzheimer's, blood sugar issues, adrenal issues, thyroid issues, all of this getting down to the order in which we eat foods. And that is on a plate. If we can have the vegetable first, that's the gastric juices.   It gets it going and flowing. Then we eat the protein next. And that will stabilize and tell our body when we're full longer.    And then the carb. And that order, even on a plate, makes a big difference to glucose levels in the blood after eating. And so that, as well as just when we're pairing foods, we do not want to have the fruit by itself.   Have it with a little bit of protein, you know, a turkey stick or something with the fruit. It's okay to have, you know, treats. But just doing it with the protein is such a huge game changer.   Laura Dugger: (42:46 - 43:06) Wonderful. Wow. You are just a wealth of information, Emily.   And wrapped up in a very warm and engaging and likable personality. But there is so much more to dig into. And I'm so grateful that you've agreed to be a returning guest.   So, thank you for everything you've shared today. And I look forward to getting to host you again.   Emily Macleod-Wolfe: (43:06 - 43:10) Thank you so much for having me, Laura. I've really had a great time. I appreciate it.   Laura Dugger: (43:10 - 43:11) My pleasure.   Emily Macleod-Wolfe: (43:12 - 43:13) Okay, let's see you next time.   Laura Dugger: (43:14 - 46:54) One more thing before you go. Have you heard the term gospel before? It simply means good news.   And I want to share the best news with you. But it starts with the bad news. Every single one of us were born sinners.   But Christ desires to rescue us from our sin, which is something we cannot do for ourselves. This means there is absolutely no chance we can make it to heaven on our own. So, for you and for me, it means we deserve death and we can never pay back the sacrifice we owe to be saved.   We need a Savior. But God loved us so much, He made a way for His only Son to willingly die in our place as the perfect substitute. This gives us hope of life forever in right relationship with Him.   That is good news. Jesus lived the perfect life we could never live and died in our place for our sin. This was God's plan to make a way to reconcile with us so that God can look at us and see Jesus.   We can be covered and justified through the work Jesus finished if we choose to receive what He has done for us. Romans 10:9 says, “That if you confess with your mouth Jesus is Lord and believe in your heart that God raised Him from the dead, you will be saved.” So, would you pray with me now?   Heavenly Father, thank you for sending Jesus to take our place. I pray someone today, right now, is touched and chooses to turn their life over to You. Will You clearly guide them and help them take their next step in faith to declare You as Lord of their life?   We trust You to work and change lives now for eternity. In Jesus' name we pray. Amen.   If you prayed that prayer, you are declaring Him for me, so me for Him. You get the opportunity to live your life for Him. And at this podcast, we're called The Savvy Sauce for a reason.   We want to give you practical tools to implement the knowledge you have learned. So are you ready to get started? First, tell someone.   Say it out loud. Get a Bible. The first day I made this decision, my parents took me to Barnes & Noble and let me choose my own Bible.   I selected the Quest NIV Bible and I love it. You can start by reading the Book of John. Also, get connected locally, which just means tell someone who's a part of a church in your community that you made a decision to follow Christ.   I'm assuming they will be thrilled to talk with you about further steps, such as going to church and getting connected to other believers to encourage you. We want to celebrate with you too, so feel free to leave a comment for us here if you did make a decision to follow Christ. We also have Show Notes included where you can read Scripture that describes this process.   And finally, be encouraged. Luke 15:10 says, “In the same way, I tell you, there is rejoicing in the presence of the angels of God over one sinner who repents.” The heavens are praising with you for your decision today.   And if you've already received this good news, I pray you have someone to share it with. You are loved and I look forward to meeting you here next time.

,Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, shows itself in four distinct personality types. These methylation personality types, methylation archetypes or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Achiever and The Athlete are very closely linked. Both are extremely ambitious, perfectionistic, competitive, and driven. Both tend to have more allergic-type reactions to the world. Things like hay fever, hives, dermatographia, and skin flushing with a workout. Neither of these personalities tend to tolerate leftovers very well (because leftovers are also high in histamine).These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin do well for these groups. Likewise, the major methyl donors tend to do well. These are SAMe, TMG, and DMG. Conversely, these groups don't do as well with folate, even the MTHFR-safe forms like L-5MTHF or folinic acid. Also, the benzodiazepine class of pharmaceuticals isn't usually the best choice (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personally, take the quiz now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comPlease support this channel by using affiliate links when you buy supplements and self-care that you wanted to buy anyway (I really appreciate it!):Seeking Health: https://bit.ly/3afXYH4Amazon: HereFullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

-- On the Show: -- Amy Klobuchar, Democratic US Senator from Minnesota, joins David to discuss the early days of the Trump administration -- Donald Trump's approval in February of the first year of his term is worse than any other President, other than his own during his first term -- Finnish writer Mikko Marttinen has a simpler explanation for what is happening with Donald Trump, arguing he's simply not intelligence and declining quickly -- Former Vice President Mike Pence publicly turns on Donald Trump, attacking him over his claim that Ukraine started the war with Russia -- Donald Trump signs a terrifying order expanding presidential power -- What happens when red states, disproportionately the takers of federal funds, run out of money? -- Piers Morgan links antidepressant SSRI medications to mass shootings in his latest tirade -- This week's Friday Feedback -- On the Bonus Show: A third of Project 2025 has been implemented, and much more...

Betches co-founder Sami Sage joins Alyssa Mastromonaco to discuss the MAGA madness from RFK Jr.'s anti-SSRI crusade to the DOGE-fueled staffing purges. Then they have a sani-petty extravaganza with Suzanne Lambert, aka liberal Regina George, and senior producer Caroline Reston. They feel petty about the Elon Musk Ashley St. Clair baby drama and White Lotus theme music, but Jack Shlossberg's social media return is keeping them sane!For a closed-captioned version of this episode, click here. For a transcript of this episode, please email transcripts@crooked.com and include the name of the podcast.RFK Jr. Goes After Widely Used Antidepressants, Claiming They Could Be A Threat To Americans (Vanity Fair 2/15)Social Security head resigns over DOGE data push (AXIOS 2/18)Food Head at FDA Resigns, Citing Numerous Job Cuts (Bloomberg 2/18)Howard University Makes History as First HBCU to Achieve Top Research Status (Diverse Education 2/13)‘We'll never run out of avocado toast': Danes launch petition to buy California (SF Chronicle 2/11)"It Sounds Like It Could Be A Bit": Rob Lowe Shares New Update On St. Elmo's Fire 2 (Screen Rant 2/8)‘Goonies 2 is officially in the Works With Steven Spielberg Producing (Variety 2/14)

Today's sponsor is Freed AI! Freed's AI medical scribe listens, transcribes, and writes notes for you. Over 15,000 healthcare professionals use Freed and you should too! Learn more here! On this episode of the Real Life Pharmacology Podcast, we will cover medications 186-190 on the Top 200 Drugs List. The medications included in the podcast episode are Sonata, Zebata, Zovirax, Coumadin, and Luvox. Sonata (ezopiclone) is a Z-drug used for insomnia. It has many similar effects to benzodiazepines and a similar mechanism of action. Zebeta (bisoprolol) is a beta-blocker used for the treatment of hypertension, atrial fibrillation, and heart failure amongst other indication. Zovirax (acyclovir) is an antiviral medication used to treat various viral infection. It needs to be dosed numerous times throughout the day which is a downside to use. Coumadin (warfarin) is an anticoagulant. It is most well known for its need to have INRs drawn to assess drug levels. Luvox (fluvoxamine) is an SSRI antidepressant. It is well known for its ability to cause drug interaction and is often not a first line agent because of this reason.

Nurses Out Loud with David Wayne, BSN-RN, CPHC – What does it take to challenge both establishment power and personal beliefs? Nora Kemmerer of Denormalize Your Life shares her awakening during COVID, questioning narratives in healthcare, nutrition, and psychiatry. She discusses hospital experiences, low-carb eating, and post-SSRI sexual dysfunction with nurse David Wayne. A compelling journey of curiosity, courage, and resilience.

Co-hosts Jared Yates Sexton and Nick Hauselman discuss how Robert Kennedy Jr is angling to get rid of SSRI's while trying to insist exercise will cure all mental health issues. Meanwhile, JD Vance's lecture to the European Union on the destruction of Democracy under the guise of free speech is met with stone cold silence and indifference. They finish by discussing the fecklessness of the Democratic Party in the face of fascistic creep. Learn more about your ad choices. Visit megaphone.fm/adchoices

Nurses Out Loud with David Wayne, BSN-RN, CPHC – What does it take to challenge both establishment power and personal beliefs? Nora Kemmerer of Denormalize Your Life shares her awakening during COVID, questioning narratives in healthcare, nutrition, and psychiatry. She discusses hospital experiences, low-carb eating, and post-SSRI sexual dysfunction with nurse David Wayne. A compelling journey of curiosity, courage, and resilience.

OCD, or Obsessive Compulsive Disorder, is a debilitating condition that involves intrusive thoughts and time-consuming, repetitive behaviors. It impacts 80 million worldwide, 2-4% of the US population or 1 in 100 people here in the US.It can be difficult to overstate the suffering caused by OCD, not only for those with this condition but also for their family members. In addition to the distress caused by the obsessional thoughts and compulsions, there can be shame and loss - loss of more meaningful, purposeful, or pleasant thoughts and behaviors. and loss of time connecting with others or engaging in purposeful or enjoyable activities.Other conditions associated with obsessive-compulsive disorder include:* Body dysmorphic disorder* Skin picking* Trichotillomania (hair pulling)* Hoarding* Hypochondria* Olfactory reference syndrome (an irrational feeling or belief that one emits a foul smell and often attempts to remove the odor).It´s not unusual for someone with OCD to have other conditions, such as:* Other forms of anxiety* Depression* ADHD* Autism spectrum disorder* Eating disorders* TourettesResearch suggests that having OCD raises one´s vulnerability to developing dementia. Many other brain conditions, however, also appear to increase this vulnerability similarly.Treatment ChallengesOCD is particularly challenging to treat. Of those with OCD, 60% do not respond to typical therapies (often medication in combination with psychotherapy involving gradual exposure to that which is being avoided). Typical medications include:* SSRI´s (Selective Serotonin Reuptake Inhibitors) -e.g., sertraline, fluoxetine, fluvoxamine, citalopram, paroxetine* Tricyclic antidepressant - clomipramine* SNRI - (Serotonin and Norepinephrine Reuptake Inhibitor) - venlafaxine* Atypical antipsychotic medications are sometimes addedMedication is combined with CBT (Cognitive Behavioral Therapy), which involves exposure and response prevention, or CBT is used alone.As you can see, most medication approaches aim to increase serotonin activity. Serotonin, however, is just one of the neurotransmitters involved. What has become increasingly clear from the research is that OCD involves abnormal activity at the NMDA receptor - a glutamate receptor.NMDA & GlutamateThe NMDA receptor is found throughout the brain. Glutamate, the primary excitatory neurotransmitter in the central nervous system, binds to the NMDA receptor. NMDA and glutamate are involved in synaptic plasticity (creating neuronal connections), learning, memory, and motor function.The synapse is the space between communicating neurons. Presynaptic neurons release glutamate, which binds to the NMDA receptor on postsynaptic neurons. This results in a cascade of signaling events that lead to “neuronal excitation.” The problem arises when this receptor has too much (or too little) activity. In the case of OCD, there is too much activity.Implications* Dysregulation at the NMDA receptor appears to play a role in OCD, depression, PTSD, schizophrenia, bipolar disorder, and substance use disorders.* Weak memory extinction can result from high activity at the NMDA receptor. While memory is a good thing, we can have problems with too much memory - or rather, problems putting our memories aside. This can look like thoughts getting stuck, for example:* Intrusive thoughts in OCD* Flashbacks in PTSD* Delusions in psychotic disorders* Cravings in addiction.* Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and ALS, have also been linked to NMDA receptor malfunction.Methylation & NMDAThose who are undermethylated, especially those with OCD or addictions, have high activity at the NMDA receptor. To remind you, undermethylation is a biochemical process with many functions, including the breakdown of histamine, support of detoxification, and support of serotonin activity. When someone is undermethylated, they can tend to have allergies (from high histamine), be perfectionistic, competitive, strong-willed, have obsessive-compulsive tendencies, be ritualistic, have dietary inflexibility, and have high accomplishment or have family members with high accomplishment. Undermethylation can contribute to the low serotonin activity seen in OCD. Simply addressing undermethylation, like merely addressing serotonin, will only bring partial benefit. To address undermethylation, those of us trained by the Walsh Research Institute, use SAMe and/or methionine, B12, B6, magnesium, and antioxidants. We address this before starting methylation treatment for those with high homocysteine. But how can we also decrease activity at the NMDA receptor?Blocking NMDA & Normalizing Glutamate ActivityEsketamine or Ketamine, which has been getting much attention in recent years, can impact the brain in various ways; however, its primary mechanism is as an NMDA blocker or antagonist. For some, it can serve as a rapid-acting and highly effective antidepressant. It can also decrease OCD symptoms. Other NMDA-blocking drugs include memantine and dextromethorphan (combined with bupropion). Lamotrigine can decrease glutamate release and has been used as an adjunct medication for OCD.Nutrients, however, play an important role in the NMDA receptor. NAC or N-acetyl cysteine is a precursor to glutathione and, thus, an antioxidant. It is also anti-inflammatory and a binder for a particular toxin made by candida and mold. But, it is also a potent NMDA antagonist (decreases activity at NMDA) and has been shown to reduce obsessions and compulsions of OCD. It has also been studied in alcoholism, opiate addiction, cocaine abuse, gambling disorder, shopping disorder, cigarette addiction, and trichotillomania. It has been used by itself and as an adjunct to medication therapy. NAC has become part of the Walsh undermethylation nutrient protocols for those with OCD and/or addiction.Zinc also plays an important role in regulating functioning at the NMDA receptor. The Walsh Research Institute found that 90% of those with brain symptoms had relatively low zinc. Dosing of zinc is determined after testing plasma zinc levels using a narrow range (the Walsh/Pheiffer range differs from typical lab ranges). Zinc is checked in conjunction with copper. Zinc has been found to improve treatment response in those with OCD treated with SSRIs. Zinc can be depleted because of very high oxidative stress and/or high pyrroles, which also cause low B6. Because B6 is needed to make serotonin, pyrroles are also important to address if elevated.Inositol is a nutrient involved in the serotonin and glutamate signaling systems. It, too, is beneficial for OCD symptoms; however, it can require very high doses.The challenge of research, as you can see, is that these approaches are all looked at in isolation, as opposed to, for example, addressing undermethylation, optimizing zinc, decreasing activity at the NMDA and addressing sources of oxidative stress.Candida & MoldAside from undermethylation, low serotonin activity, and high activity at the NMDA receptor, those with OCD appear to have high oxidative stress, as is the case with most brain-related conditions. One of the more common sources of oxidative stress I see in my practice is candida overgrowth in the GI tract, which often follows antibiotic exposure and /or mold toxicity due to water damage causing seen or unseen toxic mold. Because mold and candida (yeast) thrive on sugar and a high-carb diet, symptoms can fluctuate with sugar or carb intake. How might candida and mold intersect with the NMDA receptor? Mold and yeast can contribute to high histamine states. Histamine can increase activity at the NMDA receptor. EstrogenFor women and teen girls that I see with OCD, there is often a fluctuation in their OCD symptoms with their cycle. Typically, their symptoms worsen during the times of the month when estrogen is the highest. This may be because estrogen can increase activity at the NMDA receptor.PANDAS & PANSWhen a child has an abrupt onset of OCD symptoms, PANDAS and PANS should be considered.* PANDAS = Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections* PANS = Pediatric Acute-Onset Neuropsychiatric SyndromePANDAS and PANS are autoimmune conditions, meaning the immune system is acting on the body, in this case, a part of the brain called the basal ganglia, that involves an acute onset of OCD symptoms. Other symptoms can include restricted eating, mood symptoms, regression in academic or social skills, and motor tics. While triggers are often viral, bacterial (strep in the case of PANDAS), candida,or other microbial source, what is underlying the dysregulated immune response to such microbes, in my experience, is mold toxicity. SummaryBecause OCD can be difficult to treat, my hope in sharing this information is to raise awareness that effective OCD treatments can require a multifaceted approach that includes:* addressing methylation (and high pyrroles if present) to improve serotonin activity* decreasing activity at the NMDA receptor* by optimizing zinc* using supplements or medication* addressing sources of inflammation and high histamine* address sources of oxidative stress - trauma, stress, toxins, inflammation If you find this information helpful and would like to help me get this out into the world, please consider sharing:As always, I welcome your comments, questions, and experience.Until next time,CourtneyP.S. To learn more about non-patient consultations, treatment, and monthly mentorship groups, please visit my website at:CourtneySnyderMD.comMedical Disclaimer:This newsletter and podcast episode is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment for yourself or others, including but not limited to patients you are treating (if you are a practitioner). Consult your physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe

Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here News Topic: Unsafe at Any Speed: Dr. Toby Rogers on Darkhorse Rand Paul Speaking at RFK Jr Confirmation Hearing Restoring Freedom of Speech and Ending Federal Censorship How Trump's executive order on online free speech could upend content moderation Show Notes: Copper supplementation reverses dietary iron overload-induced pathologies in mice Filter it through a brain cell Questions:    High Iron Levels Garrett writes Robb and Nicki, I just listened to episode 202, Robb mentioned as an aside that he has high iron levels. I have the same issue, because I lived in Sweden during X years I am not able to donate blood here in the USA. What are some other means to remedy this? I'll add my values below from InsideTracker testing. 128 to 275 ug/dl range over 5 tests from the last 3 years. 34 year old fit male, diet is paleo + rice + whiskey. Protein sources are whey casein powder, chicken and red meat. Thank you! Garrett   Optimal Glucose level Tracie writes: Greetings from Spokane, WA! I reread the Paleo solution after Thanksgiving and have been pretty convinced I'll be sticking with the changes I made for life. I feel fantastic. Most of my digestive issues are gone, mood has improved, and I'm lifting more weight for more sets! I do have some anxiety/IBS that runs on my mom's side and I often feel pretty turned up, so I decided to give one of the Dexcom Stelo continuous glucose monitors a try. I was particularly stressed at work in December hiking around the woods in the snow as a forester. I noticed I'd wake up like clockwork at 11 pm and 1:30-2 am having trouble getting back to sleep, which seemed like a blood sugar low issue. Turns out I do dip down to 71 mg/dL but I'm very much in their recommended target range 99% of the time (with a little dip below 70 and so far not above 129 mg/dL post breakfast when there are tubers involved. When I wake up I'm just under 100. My question is what would you guys recommend is a more optimal glucose range? I feel like my fasted glucose in the morning should be in the 70s, and that having my blood sugar be more like 110 max after a meal would be more ideal. However, if you look/perform/feel great does it really matter? I know from your previous guests that bio individuality makes a difference and we shouldn't try to always be an A+ student. A “B” in OCHEM gets you the credit! My glucose level throughout the day is very steady around 100, I eat every 4 hours max. Breakfast at 6, a venison epic bar and satsuma tangerine at 10, chicken soup at 11:30-12:30, another venison bar and tangerine at 2:30, and dinner at 5. Breakfast and dinner is 4 ounces lean animal protein, 1/4 cup each color of fruit/vegetable, a little fat and salt for flavor. For some reference: I am a 34.5 year old female, 153 lbs, my sister is on an SSRI inhibitor/we have a family history of anxiety on moms side, familial hypercholesterolemia on dad side (so glucose control is important for avoiding heart disease) I eat 125-145 grams of protein from flank steak/smoked salmon/chicken/epic venison bars, 75-110 grams carbs from fruits/tubers/veggies, and 50-70 grams fat from animal proteins, some nuts, olive/avocado oil…and then a few times a month I stress eat some mostly paleo compliant junk snacks at work like eat a whole bag of coconut chocolate chip gluten free hippie cookies, or eat a whole Hu chocolate bar and a small bag of kettle sea salt and vinegar chips. I'm not a perfect angel, but I am 85% there. I sleep 11 hours on the weekend (cortisol induced likely), but mostly 8-8.5 with the occasional 7.8 hours. I have a lot of things going on: day job, trying to start a business, chasing moose through the woods, some of its great fun and the excitement seems to get me going too. So I have some dietary and personality factors that might drive my glucose a little higher than ideal.   Lead Testing Mari writes: Hello from North Idaho, I'm a long time listener and long time enjoyer of LMNT. I've recently become more concerned about heavy metals in what I'm consuming. I wanted to not pay attention to the chocolate situation a couple years ago because my HU bar addiction is not something I want to part with, but more keeps coming out. Recent testing done by “Clean Label Project” found a bunch of lead and cadmium in protein powders, with organic and chocolate flavored protein powders testing particularly high. I get that its a soil the chocolate in grown in thing (right?), and maybe also where/how its stored during processing? Anyways, to my point- I have an all winter long, morning LMNT hot chocolate routine. I'm also currently trying to get pregnant, so I thought I'd try to look into testing and I saw this immediately: LMNT Raw Unflavored Electrolyte Drink Mix Tests Positive for Lead: November 2024 Laboratory Report Trustworthy? No idea, which is why I was hoping you could speak to it. Thanks always for your courage and wisdom, Mari Lead Testing Hazel writes:  Hi Robb and Nicki,  I've been meaning to write to you on this topic for quite some time. I remember a few years ago there was a big to-do about heavy metals in chocolate - specifically lead and cadmium. The assertion was made, by whom I don't remember, that virtually all chocolate contained dangerous amounts of lead and we were all destined for lead poisoning if we kept eating our daily dark chocolate square. Much internet ink was spilled on the subject. Robb, you mentioned at that point that you were planning to write a piece about the bioavailabilty of that lead and whether we were really in danger. Did that ever get written? If so, please share the link! This question has come up for me again, but this time in a much broader context: there is a person on the internet who goes by the name Lead Safe Mama whose website contains pages and pages of highly alarming claims about the lead content of virtually any consumer good you can imagine - from children's and prenatal vitamins to pantry staples and cookware. She gathers this information by sending the products to a third-party lab for testing (related question: how reliable is your average third-party lab for this kind of stuff?). I don't doubt that we do have a lead contamination issue with any number of our consumer products, the same way we have a serious microplastics issue. And indeed, the LSM has been responsible for several recalls of glass products over the years based on her testing, so she's on to something. But I'm hoping you can provide more nuance to the claim that such a vast array of our products contain dangerous quantities of lead that our bodies are unable to detoxify. Do I need to add this to my ever-growing list of things to worry about? Thank you in advance for your thoughts on this.  Unrelated stuff that is too rambling to read on the pod: I REALLY value the work that you do and view you as an important voice of reason on many issues. I've been a regular listener of the show since the summer of 2020. Came for the health Q&A. Stayed for the commentary on Covid lunacy, public health, food systems, politics, and homeschooling. And who doesn't love a dog-meets-cadaverine anecdote from time to time? (Remind me the upside of pet ownership??!) Finally, the episode you did on vaccines was chilling but necessary and I thank you for sticking your neck out on that. I too deeply regret vaccinating my older child, despite pursuing a selective schedule, delaying as long as possible, only doing one dose at a time, etc. Still wish I hadn't fucking done it at all. Anyway. Keep fighting the good fight. We need you. Oh and my favorite LMNT is Citrus Salt!   All the Best,  Hazel  

This episode originally aired on January 4, 2024. In this throwback episode, Sarah accidentally buys the same glasses as Rory after making fun of them for years. Plus, she shares her experience with antidepressants, hears from a man who says her humor helped save his life and sings her favorite TV theme songs. You can leave a voice memo for Sarah at speakpipe.com/TheSarahSilvermanPodcast. Follow Sarah Silverman on Instagram @sarahkatesilverman. And stay up to date with us @LemonadaMedia on X, Facebook, and Instagram. For a list of current sponsors and discount codes for this and every other Lemonada show, go to lemonadamedia.com/sponsors. Joining Lemonada Premium is a great way to support our show and get bonus content. Subscribe today at bit.ly/lemonadapremium. See omnystudio.com/listener for privacy information.

Today's sponsor is Freed AI! Freed's AI medical scribe listens, transcribes, and writes notes for you. Over 15,000 healthcare professionals use Freed and you should too! Learn more here! On this episode of the Top 200 Drugs Podcast, I cover medications 146-150. This podcast includes; sevelamer, dalteparin, sertraline, clonazepam, and irbesartan. Sevelamer is a phosphate binder that is used to treat hyperphosphatemia in patients with chronic kidney disease. Dalteparin is a low molecular weight heparin product that is used to prevent and treat blood clots. Sertraline is a commonly used SSRI that can be helpful in managing depression and anxiety. Clonazepam is a benzodiazepine that can be used for acute relief of anxiety. Sedation, confusion, and fall risk are potential adverse effects. Irbesartan is an ARB that can be used for hypertension. Hyperkalemia and angioedema are two adverse effects to be aware of.

Today, millions of people are suffering from depression worldwide. Major depression can negatively impact your relationships, deteriorate your health, and cause problems in all aspects of your life. And when it comes to treating depression, the most common course of action tends to be antidepressant medications. Today, you're going to learn the truth about antidepressant efficacy, and the worst mental health advice coming from doctors' offices today. Our guest is psychiatrist Dr. Christopher Palmer. His research encompasses the fascinating intersection of mental health and metabolic health. Dr. Palmer is back on The Model Health Show for another powerful discussion on what causes mental health symptoms, how our current treatment plans are actually me You're going to learn why there is little evidence to support the serotonin theory of depression, and the important link between serotonin, metabolic health, and mental health. You'll also hear about the important role that nutrition plays in supporting your mental well-being, how our culture can exacerbate depression and other disorders, and how to move the needle for better mental health.    In this episode you'll discover:  The truth about SSRI efficacy. What the difference between response and remission is. The percentage of patients who experience total remission from antidepressants. What the science says about chemical imbalances. The role serotonin plays in metabolism. Why the rates of depression are at an all-time high. The connection between metabolic health and mental health. How factors like trauma and stress can impact your metabolism. The main components of healing from trauma. Signs that you're getting normal, restorative sleep. Why ultra-processed food can damage your microbiome and metabolism. How our culture perpetuates habits that cause mental health symptoms. The major problems with the US healthcare system. How to differentiate between normal feelings and mental health disorders. The importance of getting to the root cause of mental health issues. Items mentioned in this episode include:  DrinkLMNT.com/model - Get a FREE sample pack of electrolytes with any order! Organifi.com/Model  - Use the coupon code MODEL for 20% off + free shipping! Brain Energy by Dr. Christopher Palmer Connect with Dr. Christopher Palmer Website / X / Instagram  Be sure you are subscribed to this podcast to automatically receive your episodes:   Apple Podcasts Spotify Soundcloud Pandora YouTube  This episode of The Model Health Show is brought to you by LMNT and Organifi. Head to DrinkLMNT.com/model to claim a FREE sample pack of electrolytes with any purchase. Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL at organifi.com/model. 

Send us a textWhat if your mind held the key to your own healing? Join us for an insightful conversation with Craig Meriwether, a seasoned clinical and medical hypnotherapist, as we explore the transformative world of hypnotherapy. Craig sheds light on his vast experience tackling issues ranging from childhood trauma and PTSD to empowering entrepreneurs with confidence. Our discussion aims to clear the fog around hypnotherapy, debunking myths perpetuated by entertainment media, and reaffirming its voluntary nature and potential to enhance mental and emotional well-being.Discover the dual nature of hypnosis as both an entertaining spectacle and a profound healing tool. We touch upon the mind's extraordinary influence over physical health, drawing from Dr. Irving Kirsch's concept of hypnotherapy as a "non-deceptive placebo." Through captivating stories of placebo surgeries and personal battles with depression and anxiety, we underscore the mind's power to foster personal growth and healing. Craig shares his unexpected journey into hypnotherapy, sparked by a chance writing contest, which led him to uncover the mind's potential to achieve remarkable feats.From understanding the impact of subconscious messaging to overcoming public speaking fears, this episode is packed with insights. We analyze the importance of addressing subconscious traumas and stress levels, emphasizing neuroplasticity as a pathway to healing. Learn how hypnotherapy can help rewire your perceptions, influenced by the subconscious, to enhance your life. We wrap up by extending our heartfelt thanks to Craig for his invaluable insights, and inviting listeners to explore the global reach of therapy practices and the profound effects of consistent mental health strategies.Craig's website can be found athttps://arizonaintegrativehypnotherapy.com/Craig's Online Course for Test Anxiety Relief: Ace Any Test can be found athttps://aceanytest.com/Finally, download his Program Yourself For Confidence – Download 5 Free Recordings Today! athttps://aceanytest.com/boost-your-confidence/Freed.ai: We'll Do Your SOAP Notes!Freed AI converts conversations into SOAP note.Use code Steve50 for $50 off the 1st month!Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showYouTube Channel For The Podcast