Podcasts about ssri

About this episode: The FDA has long convened scientifically rigorous advisory committees to review data and offer recommendations for regulating a range of food and drug products. However, it has recently pulled back and leaned heavily into ad-hoc “expert panels” that are not held to the same standards. In this episode: Caleb Alexander, an epidemiologist and drug safety expert who has served on over a dozen FDA advisory committees, raises concerns about the lack of transparency and accountability in these new panels and suggests that their lax standards might undermine the agency's credibility. Guest: Dr. G. Caleb Alexander, MS, is a practicing internist and drug safety expert at the Johns Hopkins Bloomberg School of Public Health. Host: Lindsay Smith Rogers, MA, is the producer of the Public Health On Call podcast, an editor for Expert Insights, and the director of content strategy for the Johns Hopkins Bloomberg School of Public Health. Show links and related content: The FDA's pivot from ad comms to ‘expert' panels is bad medicine—STAT An FDA panel spread misinformation about SSRI use in pregnancy, alarming doctors—NPR Learn About FDA Advisory Committees—FDA Transcript Information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌JohnsHopkinsSPH on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

In This Episode Erin and Weer'd discuss: Maine families suing the US Army for not stopping the Lewiston Shooter; New York being ordered to pay $800K for the house of worship gun ban; the DOJ asking to speak against Assault Weapon Bans in the Illinois court challenge. Rather then Weer'd or Erin, Lara Smith of the Liberal Gun Club discusses the problems with the proposed trans gun ban; and Sean Sorrentino and Robb Allen talk about SSRI medication, the stigma against it, and why not everyone who takes SSRIs is dangerous. Did you know that we have a Patreon? Join now for the low, low cost of $4/month (that's $1/podcast) and you'll get to listen to our podcast on Friday instead of Mondays, as well as patron-only content like mag dump episodes, our hilarious blooper reels and film tracks. Show Notes Main Topic Lewiston shooting survivors, victims' families file lawsuit against US Army New York Ordered to Pay $800K After Church Challenges Ban on Firearms in Houses of Worship Following its amicus brief in support of us, the federal government has asked the Seventh Circuit for approval to participate in oral arguments in our lawsuit challenging Illinois' "assault weapon" and magazine bans Lara Smith Trump DOJ Weighs Ban on Trans People Owning Guns EXCLUSIVE: Full Transcript: Daily Caller Interviews President Donald Trump Canaries in the Gun Rights Coal Mine Liberal Gun Club Sean and Robb Robb Allen Twitter Moth, Rust, and Thieves on Spotify  

(0:00) Introducing Mark Cuban, sadness over Luka Doncic (2:38) America's broken healthcare system (15:16) State of the two-party system (19:24) Introducing Tucker Carlson (20:01) The fine line between listening and pandering, is Mamdani the Trump of the Left? (24:27) How to make Americans believe in America again (34:12) AI job displacement (39:29) Lightning round with Tucker: Epstein, Putin, why the West is killing itself, the SSRI epidemic, Iryna Zarutska murder (52:54) Antisemitism and Israel Thanks to our partners for making this happen! Solana: https://solana.com/ OKX: https://www.okx.com/ Google Cloud: https://cloud.google.com/ IREN: https://iren.com/ Oracle: https://www.oracle.com/ Circle: https://www.circle.com/ BVNK: https://www.bvnk.com/ Follow Mark Cuban: https://x.com/mcuban Follow Tucker Carlson: https://x.com/TuckerCarlson Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect

Unveiling the Truth: Psychiatric Drug Withdrawal and Its Hidden Side EffectsIn this compelling episode of The Kelsi Sheren Perspective, we delve into the intricate relationship between the pharmaceutical industry and mental health with Dr. Josef Witt-Doerring, a leading expert in psychiatric drug side effects and withdrawal. Dr. Josef shares his journey from working within the pharmaceutical industry to advocating for safer psychiatric practices. We explore the challenges of psychiatric drug withdrawal, the ethics of pharmaceutical practices, and the importance of informed decision-making in mental health treatment. Join us for an eye-opening discussion that challenges the status quo and offers hope for those seeking alternative paths to mental wellness.⁠https://taperclinic.com/dr-josef-witt-doerring/⁠Substack: https://substack.com/@kelsisheren - - - - - - - - - - - -SUPPORT OUR SPONSORS - - - - - - - - - - - -Ketone IQ- 30% off with code KELSI - https://ketone.com/KELSIGood Livin- 20% off with code KELSI - https://www.itsgoodlivin.com/?ref=KELSIBrass & Unity - 20% off with code UNITY - http://brassandunity.com - - - - - - - - - - - - -SHOPB&U Jewelry & Eyewear: https://brassandunity.com - - - - - - - - - - - - -Follow #thekelsisherenperspective- - - - - - - - - - - - -CHARITYHeroic Hearts Project - https://www.heroicheartsproject.orgAll Secure Foundation - http://allsecurefoundation.orgDefenders of Freedom -https://www.defendersoffreedom.usBoot Campaign - https://bootcampaign.org

Origin story from entertainment to podcasting, theosophical influences (Blavatsky, Bailey), Hegel's dialectic/technocracy, propaganda/cybernetic loops, psychedelics, sexual revolution, and staying grounded amid information overload. During our podcast break, enjoy this replay of Courtenay's appearance on The Will Spencer Podcast from May 2025. Key topics: Courtenay's origin story: Awakening in 2020 from entertainment/fitness world to podcasting, spurred by isolation, masking, and research into medical freedom and Tavistock/Frankfurt School influences. Occult theosophical roots: Helena Blavatsky, Alice Bailey, Theosophical Society, and their impact on New Age, education (e.g., social emotional learning), transhumanism, and global governance. Philosophical threads: Hegel's dialectic as a gnostic Jacob's Ladder, accelerationism (Nick Land, Curtis Yarvin), and the technological immanentization of the eschaton/singularity. Societal shifts: Sexual revolution's depopulation agenda, identity politics, psychedelics (e.g., SSRI alternatives, Elon Musk/Peter Thiel's synthetic therapies), and the compassion trap. Media and cognition: Cybernetic feedback loops, algorithmic silos, voyeuristic intellectualism, and the decline of reading/inner monologue, with AI's role in education. Hope and grounding: Exercising free will, planting seeds of truth, and resisting wizard circles through discernment and relationships. Read Courtenay's Article: ⁠https://courtenayturner.substack.com/p/hegels-dialectic-a-gnostic-jacobs⁠ Follow and Connect with Will Spencer:

Victor Davis Hanson explains why this was not simply a tragedy, but an act of evil, and why the media and political leaders refuse to have an honest discussion about the factors behind it on today's episode of “Victor Davis Hanson: In His Own Words.” “They won't have any discussion over transgenderism. This falls in the broader category of exempt DEI woke topics, but I think we should talk about this. This is the fourth or fifth incident—I don't even like the word "incident"—occurrence of transgendered shooters who are protected by authorities. “We were told, "Be careful about Big Pharma. Be careful about Big Med." All of those worries and prohibitions and cautions were thrown out the window, as were SSRI antidepressants. These were selective serotonin prohibitors. In other words, they altered the chemistry of the brain, supposedly, to correct mental disturbances, depression, bipolarity. But they're very dangerous drugs. But when it came to the exempt topic of transgenderism, suddenly the society was supposed to accept that this was not a mental disorder. It was not a rare occurrence. It was a national crisis where large percentages of the population were transgendering.”

Todays show is sponsored by: Beam Are you tossing and turning at night and running on fumes during the day? If so, then you are missing out on the most important part of your wellness, sleep. If you want to wake up refreshed, inspired and ready to take on the day then you have to try Beam's Dream powder. This best-selling blend of Reishi, Magnesium, L-Theanine, Apigenin and Melatonin will help you fall asleep, stay asleep, and wake up refreshed. So if you're ready for the best night of sleep you ever had just head to https://shopbeam.com/SPICER to receive 40% off your order. Firecracker Farms Everything's better with HOT SALT. Firecracker Farms hot salt is hand crafted on their family farm with Carolina Reaper, Ghost and Trinidad Scorpion peppers. This is a balanced, deep flavor pairs perfect with your favorite foods. Whether it's eggs, steaks, veggies or even your favorite beverage, Firecracker Farms hot salt is what you've been missing. Just head to https://firecracker.farm/ use code word: SEAN for a discount. Unlock the flavor in your food now! President Trump squashed the propagandist media once and for all about him being dead or unhealthy with an epic press conference on the oval office. Jessica Millan Patterson is taking the fight to Gavin Newsom and his gerrymandering effort in California. The California Citizens Redistricting Commission set the Congressional districts in 2021. Redistricting in California is nothing more than a power grab and as the Chair of Stop Prop 50, Jessica is ready to stop Newsom in his tracks. As Virginia schools struggles with transgenders and bathrooms, Ian Prior is here to fill us in on all the legal matters, including cases taken to the Supreme Court. Will we finally get a definitive answer on Title IX? RFK Jr. is tackling SSRIs as another trans-identifiying shooter tragically shot and injured 21 people at Annunciation Catholic school in Minnesota. Two children, Fletcher Merkel and Harper Myoski lost their lives. Penny Nance and Concerned Women for America are calling for the experts to identify how SSRI's and gender-affirming drugs may play a role in these tragic incidents. Featuring: Jessica Millan Patterson Chairwomen | Stop Prop 50 https://stop50.org/ Ian Prior Senior Advisor | America First Legal https://aflegal.org/ Penny Nance CEO | CWA https://concernedwomen.org/ ------------------------------------------------------------- 1️⃣ Subscribe and ring the bell for new videos: https://youtube.com/seanmspicer?sub_confirmation=1 2️⃣ Become a part of The Sean Spicer Show community: https://www.seanspicer.com/ 3️⃣ Listen to the full audio show on all platforms: Apple Podcasts: https://podcasts.apple.com/us/podcast/the-sean-spicer-show/id1701280578 Spotify: https://open.spotify.com/show/32od2cKHBAjhMBd9XntcUd iHeart: https://www.iheart.com/podcast/269-the-sean-spicer-show-120471641/ 4️⃣ Stay in touch with Sean on social media: Facebook: https://facebook.com/seanmspicer Twitter: https://twitter.com/seanspicer Instagram: https://instagram.com/seanmspicer/ 5️⃣ Follow The Sean Spicer Show on social media: Facebook: https://facebook.com/seanspicershow Twitter: https://twitter.com/seanspicershow Instagram: https://instagram.com/seanspicershow Learn more about your ad choices. Visit megaphone.fm/adchoices

Thank you Sabrina 'The Unyielding' Tran, OMS IV, for developing this podcast topic! Thank you Cynthia Sharma, OMS IV, for being a great sidekick!This podcast starts with high yield information about SSRI discontinuation syndrome and Lithium toxicity. The discussion then dives into the nuances of how either a Roux-and-Y or Sleeve Gastrectomy may affect blood levels of various medications. This is a technical discussion that has great information! We enjoyed our discussion and hope you do too!Thank you to the physicians that have blazed the podcast pathway over the last half decade. Thank you to the new students that carry the torch! Thank you to the immortal Jordan Turner for creating the perfect bumper music! Most of all, thank you to everybody that listens in and learns with us.

Hello good human, and welcome to the first episode of The Sunshine Project recorded under the influence (of a Selective Serotonin Reintake Inhibitor). I’ve trotted off to the pharmacy to pick up something that will hopefully help me feel less like I’m being chased by a wild tiger all of the time - fight or flight has really been fight or flighting lately - and so today, I want to talk about what’s been going on, and why I’m giving medication a go. Happy listening xxxSee omnystudio.com/listener for privacy information.

We're seeing an epidemic of transgender mass murderers. They were all seriously depressed, and likely on SSRIs that can cause murderous thoughts. There are serious roadblocks to being able to identify them before they kill innocents.It's essential that we create a safe harbor in HIPAA for reporting these deranged people before they pull the trigger. It's also essential that we get rid of the orthodoxy that transgender is somehow "normal."And, BTW, "assault weapon" is a meaningless term.

01:02:09 – Shooter's Demonic Diary The Minneapolis church shooter's writings reveal regret over being trans, self-brainwashing, and violent fantasies. Media figures like Jake Tapper tie themselves in knots over pronouns while ignoring the manifesto's satanic themes. 01:10:15 – Stephen King Defends Trans Shooter King dismisses transgender ideology as a factor, blaming guns instead. Hosts argue the real problem is cultural rot, demonic influence, and a clear pattern of trans-linked shootings disproportionately targeting Christians. 01:16:07 – Psaki Mocks Prayer After Massacre Former White House press secretary Jen Psaki derides “thoughts and prayers” after Christian children are gunned down, sparking backlash. The commentary argues school shootings increased precisely because prayer was removed from schools. 01:27:29 – SSRIs and Mass Killings RFK Jr. calls for a probe into antidepressants. Studies and 7,000+ case reports show SSRIs linked to homicidal ideation, murder-suicides, and violent psychosis, especially among trans-identified youth already under institutional grooming pressures. 01:58:23 – Church Security and Great Replacement Closing segment pivots from the massacre to broader concerns: failures of Catholic school security, migrant violence, and reckless foreign truck drivers in Tennessee. Framed as part of the “great replacement” and systemic government negligence. 02:01:50 – Red Flags vs. Black Labels Commentary slams gun control hypocrisy, arguing the real threat isn't lawful gun owners but SSRI drugs causing homicidal ideation. Instead of “red flag” laws, America needs warning “black labels” on dangerous pharmaceuticals. 02:13:00 – Foreign Trucking Crisis An Indian driver, drunk and barreling the wrong way across Memphis in an 18-wheeler, highlights a growing crisis: poorly vetted foreign truckers with California licenses endangering Americans nationwide. The DOT is accused of negligence. 02:21:17 – Illegal Alien Maserati Crash In Nashville, an illegal Honduran with a revoked status and prior convictions drove a Maserati drunk, killing and injuring Americans. Framed as part of the “Great Replacement,” where foreign criminals are protected while citizens suffer. 02:25:12 – Walmart's H-1B Visa Scam Scandal erupts as Walmart fires 1,200 tech contractors amid allegations of a $30,000-per-day kickback scheme tied to H-1B visas. Critics say corporate elites use foreign labor to gut the American middle class. 02:48:20 – Python Wars & Brain Chips Florida deploys $4,000 “robot rabbits” to lure invasive Burmese pythons destroying wildlife, while China advances brain-computer interface programs for totalitarian control. Both framed as government-backed “solutions” that could spiral into bigger dangers. 03:05:33 – India's War on Christianity India passes radical anti-conversion laws allowing life in prison for sharing the Gospel, framed as “freedom of religion” amendments. Critics say Tulsi Gabbard's ties to Modi's party expose the hypocrisy and danger for Christians worldwide. 03:08:00 – Same-Sex Marriage Reconsidered Discussion of Obergefell resurfaces, with Clarence Thomas signaling it rests on the same shaky legal ground as Roe v. Wade. Marriage redefinition is framed as a state power grab that undermines children's rights to their biological parents. 03:16:38 – GOP Support for Gay Marriage Collapses Republican support for same-sex marriage drops sharply since 2021. Panelists call for conservatives to finally “conserve something,” noting Trump and Melania openly celebrated LGBT policies despite presenting themselves as cultural defenders. 03:21:43 – Law Without Moral Foundation Debate over “substantive due process” shows how courts manufactured rights like abortion and gay marriage. The commentary insists law requires a moral foundation, warning against turning children into state-owned commodities. 03:53:18 – Peter Thiel's Tech Bilderberg Peter Thiel launches “Dialogue,” a secretive DC-based club for tech elites, Treasury officials, and politicians (including Tulsi Gabbard & Ted Cruz). Framed as a “Bilderberg 2.0,” critics say it's a transhumanist push to eliminate AI regulation. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silverFor 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHTFind out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

Imagine the huevos on the criminal illegal alien wife beating human trafficking gang banger Kilmar Garcia for him to ask a judge to slap a gag order on Pam Bondi and Kristi Noem. Wait until you hear why. RFK announces an investigation into SSRI's - "something's changed" in the US that's caused a spike in gun violence. A brilliant supercut of media clips shows how the left walks in lock step when covering trans killings. Good News takes us to upstate New York when a woman watching a livestream becomes an unusual first responder.

01:02:09 – Shooter's Demonic Diary The Minneapolis church shooter's writings reveal regret over being trans, self-brainwashing, and violent fantasies. Media figures like Jake Tapper tie themselves in knots over pronouns while ignoring the manifesto's satanic themes. 01:10:15 – Stephen King Defends Trans Shooter King dismisses transgender ideology as a factor, blaming guns instead. Hosts argue the real problem is cultural rot, demonic influence, and a clear pattern of trans-linked shootings disproportionately targeting Christians. 01:16:07 – Psaki Mocks Prayer After Massacre Former White House press secretary Jen Psaki derides “thoughts and prayers” after Christian children are gunned down, sparking backlash. The commentary argues school shootings increased precisely because prayer was removed from schools. 01:27:29 – SSRIs and Mass Killings RFK Jr. calls for a probe into antidepressants. Studies and 7,000+ case reports show SSRIs linked to homicidal ideation, murder-suicides, and violent psychosis, especially among trans-identified youth already under institutional grooming pressures. 01:58:23 – Church Security and Great Replacement Closing segment pivots from the massacre to broader concerns: failures of Catholic school security, migrant violence, and reckless foreign truck drivers in Tennessee. Framed as part of the “great replacement” and systemic government negligence. 02:01:50 – Red Flags vs. Black Labels Commentary slams gun control hypocrisy, arguing the real threat isn't lawful gun owners but SSRI drugs causing homicidal ideation. Instead of “red flag” laws, America needs warning “black labels” on dangerous pharmaceuticals. 02:13:00 – Foreign Trucking Crisis An Indian driver, drunk and barreling the wrong way across Memphis in an 18-wheeler, highlights a growing crisis: poorly vetted foreign truckers with California licenses endangering Americans nationwide. The DOT is accused of negligence. 02:21:17 – Illegal Alien Maserati Crash In Nashville, an illegal Honduran with a revoked status and prior convictions drove a Maserati drunk, killing and injuring Americans. Framed as part of the “Great Replacement,” where foreign criminals are protected while citizens suffer. 02:25:12 – Walmart's H-1B Visa Scam Scandal erupts as Walmart fires 1,200 tech contractors amid allegations of a $30,000-per-day kickback scheme tied to H-1B visas. Critics say corporate elites use foreign labor to gut the American middle class. 02:48:20 – Python Wars & Brain Chips Florida deploys $4,000 “robot rabbits” to lure invasive Burmese pythons destroying wildlife, while China advances brain-computer interface programs for totalitarian control. Both framed as government-backed “solutions” that could spiral into bigger dangers. 03:05:33 – India's War on Christianity India passes radical anti-conversion laws allowing life in prison for sharing the Gospel, framed as “freedom of religion” amendments. Critics say Tulsi Gabbard's ties to Modi's party expose the hypocrisy and danger for Christians worldwide. 03:08:00 – Same-Sex Marriage Reconsidered Discussion of Obergefell resurfaces, with Clarence Thomas signaling it rests on the same shaky legal ground as Roe v. Wade. Marriage redefinition is framed as a state power grab that undermines children's rights to their biological parents. 03:16:38 – GOP Support for Gay Marriage Collapses Republican support for same-sex marriage drops sharply since 2021. Panelists call for conservatives to finally “conserve something,” noting Trump and Melania openly celebrated LGBT policies despite presenting themselves as cultural defenders. 03:21:43 – Law Without Moral Foundation Debate over “substantive due process” shows how courts manufactured rights like abortion and gay marriage. The commentary insists law requires a moral foundation, warning against turning children into state-owned commodities. 03:53:18 – Peter Thiel's Tech Bilderberg Peter Thiel launches “Dialogue,” a secretive DC-based club for tech elites, Treasury officials, and politicians (including Tulsi Gabbard & Ted Cruz). Framed as a “Bilderberg 2.0,” critics say it's a transhumanist push to eliminate AI regulation. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silverFor 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHTFind out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

table {mso-displayed-decimal-separator:"."; mso-displayed-thousand-separator:",";} tr {mso-height-source:auto;} col {mso-width-source:auto;} td {padding-top:1px; padding-right:1px; padding-left:1px; mso-ignore:padding; color:black; font-size:11.0pt; font-weight:400; font-style:normal; text-decoration:none; font-family:"Aptos Narrow", sans-serif; mso-font-charset:0; text-align:general; vertical-align:bottom; border:none; white-space:nowrap; mso-rotate:0;} .xl38 {color:#131313; font-family:Roboto; mso-generic-font-family:auto; mso-font-charset:0; white-space:normal;} On RISING today, RFK Jr. confirms investigation into potential SSRI link to violence after MN mass shooting. Trump floats 2026 midterm convention; Dems mull over the same. Trump yanks Secret Service protection for Harris after Biden extended it. Trump admin. to limit foreign student visa duration in crackdown on abuse. Judge orders Alligator Alcatraz to close; Homan slams 'radical decision.' Trump signs executive order mandating classical architecture style as DC default. Adam Friedland confronts Ritchie Torres over Israel support. Newsom: World leaders 'laughing' at Trump, warns of Trump staying in power beyond 2028. All this, and more. #Rising  Learn more about your ad choices. Visit megaphone.fm/adchoices

Are Guns or SSRI drugs responsible for mass shootings? The mentality of Gun Control people, More evidence the media sucks, Trump is loved for the same reasons he's hated, Larry Elder, Gavin Newsome and why extremists suck.

RFK Jr. is now researching the effects of SSRI drugs and harm it can potentially cause psychologically. See omnystudio.com/listener for privacy information.

Here's your Daily dose of Human Events with @JackPosobiecThe only thing worse than getting hacked is knowing you could have stopped it and didn't take action when you could have. So go to https://www.PATRIOT-PROTECT.COM/POSO  and use promo code Poso for 15% off a yearly subscription.Support the show

Today we cover more of John Coleman's forgotten predictive text from the 90s as well as films that accidentally predicted where we are in culture, and more secrets of Klaus and the popes. https://www.eventbrite.com/e/athens-jerusalem-orthodox-art-philosophy-life-tickets-1598008298839?aff=oddtdtcreator Send Superchats at any time here: https://streamlabs.com/jaydyer/tip Join this channel to get access to perks: https://www.youtube.com/channel/UCnt7Iy8GlmdPwy_Tzyx93bA/join PRE-Order New Book Available in Sept here: https://jaysanalysis.com/product/esoteric-hollywood-3-sex-cults-apocalypse-in-films/ Get started with Bitcoin here: https://www.swanbitcoin.com/jaydyer/ The New Philosophy Course is here: https://marketplace.autonomyagora.com/philosophy101 Set up recurring Choq subscription with the discount code JAY44LIFE for 44% off now https://choq.com Lore coffee is here: https://www.patristicfaith.com/coffee/ Subscribe to my site here: https://jaysanalysis.com/membership-account/membership-levels/ Follow me on R0kfin here: https://rokfin.com/jaydyer Music by Amid the Ruins 1453 https://www.youtube.com/@amidtheruinsOVERHAUL Join this channel to get access to perks: https://www.youtube.com/channel/UCnt7Iy8GlmdPwy_Tzyx93bA/join Join this channel to get access to perks: https://www.youtube.com/channel/UCnt7Iy8GlmdPwy_Tzyx93bA/join #comedy #religion #podacstBecome a supporter of this podcast: https://www.spreaker.com/podcast/jay-sanalysis--1423846/support.

Dr. Chris Masterjohn is the host of the Mastering Nutrition Podcast and founder of Mitome, where he helps people optimize their mitochondrial health through advanced analysis. He received his PhD in Nutritional Sciences from the University of Connecticut, completed his postdoctoral research at the University of Illinois, and served as Assistant Professor at Brooklyn College before choosing to work independently - free from institutional constraints - in science research and education. His groundbreaking SSRI series on his substack hasn't just exposed the truth about these drugs. It's revealed that we've been looking at them completely wrong. Dr. McFillin and Dr. Masterjohn expose how these drugs act as mitochondrial toxins, disrupt cellular energy, and deplete serotonin. They also explore the consequences no one talks about: from prenatal exposure to why so many patients say they feel “dead inside.”Chris Masterjohn, PhD Website Dr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

Mark and Melynda discuss Former President Obama's criticisms of President Trump deploying the National Guard domestically, a Woodlands hospital worker hiding cameras, and RFK Jr. looking into SSRI's as a possible cause of violence in young people.See omnystudio.com/listener for privacy information.

Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimizing therapy and preventing downstream prescribing problems. Mechanism of ActionVilazodone is classified as a selective serotonin reuptake inhibitor (SSRI) and a partial agonist at the 5-HT1A receptor. The SSRI activity increases synaptic serotonin by blocking the serotonin transporter, while partial agonism at 5-HT1A receptors may contribute to antidepressant effects and potentially reduce certain SSRI-associated adverse effects (though clinical evidence for this benefit is mixed). Adverse Effects GI effects – diarrhea, nausea, and vomiting are frequent early in therapy. Taking the medication with food can help minimize these. Insomnia – often dose-related; morning dosing may help. Sexual dysfunction – may be slightly lower than with some SSRIs but still present. Serotonin syndrome – rare but serious, particularly if combined with other serotonergic drugs. Discontinuation syndrome – abrupt cessation can lead to dizziness, irritability, and flu-like symptoms. Drug InteractionsVilazodone is primarily metabolized by CYP3A4. This means: CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase vilazodone concentrations, potentially worsening side effects—dose reductions may be required. CYP3A4 inducers (e.g., carbamazepine, rifampin, St. John's Wort) can lower drug levels, reducing effectiveness. Other serotonergic agents (e.g., triptans, SNRIs, MAOIs, tramadol, linezolid) increase the risk of serotonin syndrome. Antiplatelets and anticoagulants – SSRIs can impair platelet aggregation, increasing bleeding risk when combined with aspirin, NSAIDs, or warfarin. Prescribing Cascade ExamplesVilazodone's adverse effects can easily lead to unnecessary prescriptions if side effects aren't recognized: GI upset → Acid suppression therapy – Diarrhea or nausea prompts the addition of proton pump inhibitors or antiemetics, instead of adjusting vilazodone dose or timing. Insomnia → Hypnotic initiation – Trouble sleeping results in adding zolpidem or trazodone, without reassessing morning dosing or vilazodone's role. Sexual dysfunction → PDE5 inhibitor prescription – Erectile dysfunction leads to sildenafil use, when the root cause is vilazodone's serotonergic activity. Vilazodone's combination of SSRI and 5-HT1A partial agonist activity makes it somewhat distinct, but its side effect profile and interactions require the same careful monitoring as other antidepressants. Healthcare professionals can play a key role in catching early signs of adverse effects, preventing prescribing cascades, and ensuring drug–drug interactions are managed appropriately.

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HR3 Mental Health Issues, Circulation Issues, SSRI's 8-6-25 by John Rush

Parkinson disease is a neurodegenerative movement disorder that is increasing in prevalence as the population ages. The symptoms and rate of progression are clinically heterogenous, and medical management is focused on the individual needs of the patient. In this episode, Kait Nevel MD, speaks with Ashley Rawls, MD, MS, author of the article “Parkinson Disease” in the Continuum® August 2025 Movement Disorders issue. Dr. Nevel is a Continuum® Audio interviewer and a neurologist and neuro-oncologist at Indiana University School of Medicine in Indianapolis, Indiana. Dr. Rawls is an assistant professor at the University of Florida Health, Department of Neurology at the Norman Fixel Institute for Neurological Diseases in Gainesville, Florida Additional Resources Read the article:  Parkinson Disease Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @IUneurodocmom Guest: @DrRawlsMoveMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Nevel: Hello, this is Dr Kait Nevel. Today I'm interviewing Dr Ashley Rawls about her article on Parkinson disease, which appears in the August 2025 Continuum issue on movement disorders. Ashley, welcome to the podcast, and please introduce yourself to the audience. Dr Rawls: Thank you, Kait. Hello everyone, my name is Dr Ashley Rawls. I am a movement disorder specialist at the University of Florida Fixel Institute for Neurologic Diseases in Gainesville, Florida. It's a pleasure to be here. Dr Nevel: Awesome. To start us off talking about your article, can you share what you think is the most important takeaway for the practicing neurologist? Dr Rawls: Yes. I would say that my most important takeaway for this article is that Parkinson disease remains a clinical diagnosis. I think the field has really been advancing and trying to find a biomarker to help with diagnosis through ancillary testing. For example, with the dopamine transporter, the DAT scan, an alpha-synuclein skin biopsy, an alpha-synuclein amplification assay that can happen in blood and CSF. However, I think it's so critical to make sure that you have a very strong history and a very thorough physical exam and use those biomarkers or other testing to help with, kind of, bolstering your thoughts on what's going on with the patient. Dr Nevel: Great. And I can't wait to talk a little bit more about the ancillary testing and how you use that. Before we get to that, can you review with us some of the components of the clinical diagnosis of Parkinson disease? Dr Rawls: Yes. So, when I think about a person that comes in that might have a neurodegenerative disease, I think about two different features, mainly: both motor and Manon motor. So, for my motor features, I'm thinking about resting tremor, bradykinesia---which is fullness of movement with decrement over time---rigidity, and then a specific gait disturbance, a Parkinsonian gait, involving stooped posture, decreased arm swing. They can also have reemergent tremor while walking if they do have tremor as part of their disease process, and also in-block turning as they are walking down the hallway. So, those are my motor features that I look for. So now, when we're talking about a specific diagnosis of Parkinson disease, the one motor feature that you need to have is bradykinesia. The reason why I make sure to speak about bradykinesia, which is slowness of movement with decrement over time, is because people can still have Parkinson disease without having tremor, a resting tremor. So even though that's one of the core cardinal features that most of us will be able to notice very readily, you don't have to necessarily have a resting tremor to be diagnosed with Parkinson' disease. When I talk about nonmotor features, those are going to be the three, particularly the prodromal features that can occur even ten years before people have motor features, can be very prominent early on in the disease process. For example, hyposmia or anosmia for decrease or lack of sense of smell. Another one that we really look for is going to be RBD, or rapid eye movement behavior disorder; or REM behavior disorder, the person acting out their dreams, calling out, flailing their limbs, hitting their bed partner. And then the other one is going to be severe constipation. So those three prodromal nonmotor symptoms of hyposmia/anosmia, RBD or REM behavior disorder, and severe constipation can also make me concerned as a red flag that there is a sort of neurodegenerative issue like a Parkinson disease that may be going on with the patient. Dr Nevel: Great, thank you so much for that overview. While we're talking about the diagnosis, do you mind kind of going back to what you mentioned in the beginning and talking about the ancillary tests that sometimes are used to kind of help, again, bolster that diagnosis of Parkinson disease? You know, like the DAT or the alpha-synuclein skin biopsy. When should we be using those? Should we be getting these on everyone? And what scenarios should we really consider doing one of those tests? Dr Rawls: The scenario in which I would order one of the ancillary testing, particularly like a DAT scan or a skin biopsy, looking for alpha-synuclein is going to be when there are potential red flags or a little bit of confusion in regard to the history and physical that I need to have a little bit more clarification on. For example, if I have a patient that has a history of using dopamine blocking agents, for example, for severe depression; or they have a history of cancer diagnosis and they've been on a dopamine agent like metoclopramide; those I want to be mindful because if they're coming in to see me and they're having the symptoms of Parkinsonism---which is going to be resting tremor, bradykinesia rigidity, or gait disturbance---I need to try to figure out is it potentially due to a medication effect, particularly if they're still on the dopamine blockade medication, or is it something where they're actually having a neurodegenerative illness underneath it, like a Parkinson disease? The other situation that would make me order a DAT skin or a skin biopsy is going to be someone who is coming in that maybe has elements of essential tremor, they have more of a postural or an intention tremor that's very flapping and larger amplitude, and maybe have some mild symptoms and Parkinsonism that might be difficult to distinguish between other musculoskeletal things like arthritis, other imbalance issues from, you know, hip problems or knee problems and what have you. Then I might say, okay, let's see if there is some sort of neurodegeneration underneath this; that may be- that there could be, you know, potentially two elements like a central tremor and Parkinson disease going on. Or is this someone who actually really has Parkinson disease, but there's other factors that are kind of playing into that. Dr Nevel: Great, thank you for that. Gosh, things have really changed over the past fifteen years or so where we have this ancillary testing that we're able to use more, because what you read in the textbook isn't always what you see in clinic. And as you described, there are patients who… it's not as clear cut, and these tests can be helpful. Could you tell us more about the levodopa challenge test? How is this useful in clinical practice? And what are some key points that we should know about when utilizing this strategy for patients who we think have Parkinson disease? Dr Rawls: So, before we had all this ancillary testing with the DAT scan, the skin biopsy, the alpha-synuclein amplification assay, many times if you had a suspicion that a person that had Parkinson disease, but you weren't entirely sure, you would say, hey, listen, let us give you back the dopamine that your body may be missing and see if you have an improvement, in particular in your motor symptom. So, when I talk with my patients, I say, listen, I might have a strong suspicion that you have Parkinson disease. Doing a levodopa trial can not only be diagnostic, but also can be therapeutic as well. So, with this levodopa trial, what I end up doing is saying, okay, we're going to start the medication at a low dose because we are looking to see if you have improvement in three of the main cardinal motor symptoms. Obviously, tremor is much easier for us to see if it gets better. It's very obvious on exam, and the patients are more readily able to see it. Whereas stiffness and slowness is much harder to quantify and try to figure out. Am I stiff and slow because of potential muscle tightness from Parkinson disease, or is it something that's more of a musculoskeletal issue? So, I will tell persons, okay, we're looking for improvement in these three cardinal motor symptoms, and things that we're looking for is getting into and out of a car, into and out of a chair, turning over in bed, seeing how do we navigate ourselves in our daily lives? I give people the example of going through the grocery store, going through a busy airport. Are we able to move better and respond better to different changes in our environment which can give us a better clue of if our stiffness and slowness in particular are being improved with the medication? The other part of this is talking about potential side effects of the carbidopa- of the levodopa in particular. One big thing that I think limits people initially is going to be the nausea, vomiting, potential GI upset when starting this medication initially. So, oftentimes I will find people coming in, oh, you know, my outside doctor started me immediately on one tab of carbidopa/levodopa three times per day. I got nauseous, I threw up, and I never took the medication again. So often times I will start low and go slow because once someone throws up my medication, they are not going to want to take it again---with good reason. So, often times I will ask the patient, hey listen, are you very sensitive to medications? If you are very sensitive, we might start one tablet per day for a week, one tablet twice a day, and then go up until we get to two tablets three times a day if we're talking about carbidopa/levodopa. If someone is not as sensitive then I might go up a little bit quicker. What do we mean when we talk about 600 milligrams per day? So usually, the amount that I use is carbidopa/levodopa, 25/100; so, 100 milligrams being the levodopa portion. Many people just start off at 1 tab 3 times a day, which gives you 300 milligrams of levodopa, and they say, oh, it didn't work, I must not have Parkinson or something else. Well, it just may have been that we did not give an adequate trial and adequate dose to the person. Now if they're not able to tolerate the medication because of the side effects, that's something different. But if they don't have side effects and don't notice a difference, there is room to increase the carbidopa/levodopa or the levodopa replacement that you are using so that you can give it, you know, a very good try to see, is it actually improving resting tremor, bradykinesia and rigidity? Dr Nevel: Yeah, great. Thanks for that. When you diagnose a patient with Parkinson disease, how do you counsel that patient? How do you break that difficult news? And how do you counsel them on what to expect in the future and goals of treatment? I know that's a lot in that question, but it also is a lot that you do in one visit, oftentimes, or at least introduce these kind of concepts to patients in a single visit. Dr Rawls: One thing that I think is helpful for me is trying to understand where the patients and their families are when they come in. Because some of the patients come in and have no prior inkling that they may have a neurodegenerative illness like Parkinson disease. Some of my patients come in and say, I'm here for a second opinion for Parkinson disease. So, then I have an idea of where we are in regard to potential understanding of how to start the conversation going forward. If it is someone who is coming in and has not heard about Parkinson disease, or their family has not been made aware that that's the one reason why they're coming to see a movement disorder specialist, then I will start at the beginning After we finish our history, do a very thorough physical exam, I will talk about things that I heard in the history and that I see on the physical exam that make me concerned for a disease like Parkinson disease. I make sure to tell them where I'm getting my criteria from and not just start off, I think you have Parkinson, here's your medication. I think that's very jarring when you're talking with patients and their families, particularly if they had no idea that this could be a potential diagnosis on the table. Like I said, I will start off with recounting, this is what I've heard in your history that makes me concerned. This is what I've seen on your physical exam that makes me concerned. And I think you have Parkinson disease and here is why. And I'll tell them about the tenants like we discussed about Parkinson disease, both the motor and nonmotor symptoms that we see. So that's kind of the first part is, I make sure to lay it out and then open the room up for some questions and clarification. The other portion of this is that, when I'm talking about counseling the patient, I say, we do not expect Parkinson disease to decrease your lifespan. However, over time, our persons, because it is a neurodegenerative illnesses will accumulate deficits over time. So, more stiffness, more slowness, more walking problems. They may, if they have tremor, the tremor may become worse. If they don't have tremor, they might develop tremor in the future. If we're talking about the nonmotor symptoms that we talk about, the main ones are going to be issues with urinary problems, issues with bowels, and then the other thing is going to be neuropsychiatric issues like anxiety and depression. And those things become more prominent, usually, the nonmotor symptoms later on in the disease process, and then also cognitive impairment as well. I really want to make sure that they have the information that I'm seeing, and if there's anything that they want to correct on their end, as in they're saying, oh wait, well, actually I noticed something else, then that's usually when that comes out around kind of the wrapping-up portion of the visit. So, I think that's really important to, one, be very clear in what I am seeing and if there's red flags, and then tell them, okay this is not going to shorten your lifespan. However, over time, we do have other issues and problems that will arise and we can support you as best as we can through that. The one thing I also been very open with people about is- because our patients will say, is there anything I can do? What can be done? Is there any medication to slow down or stop things? And I let people know that unfortunately, right now there's not an intervention that slows down, stops, or reverses disease progression, with the exception of exercise. Consistent exercise has been found to help to slow down disease progression, okay? And also, it can help to release the dopamine already being made innately in the brain. And also, it can help with our cardiovascular health in the big thing: being balanced. Core strength, quadricep strength. So that's also something that people can work on that they should. And I let people know that exercise is as important as the medications themselves. Dr Nevel: Absolutely. And it's incredible how much they incorporate exercise into their daily lives and get active, people who weren't active before their diagnosis, and how much that can help. One question that I think patients sometimes ask is, when they understand how carbidopa/levodopa works and what the expectations are for that medication, that it's not a disease-modifying medication, but that it can help with their symptoms. And then they kind of hear, well as time goes on, they need higher doses or, you know, it doesn't control their motor symptoms as well. They'll say, okay well, is it better to wait then? Should I wait to start carbidopa/levodopa? Like in my mind, I'm only maybe going to get X amount of time from carbidopa/levodopa. So, I'd rather wait to start it than start it now. What do you say to them and how do you counsel them through that? Dr Rawls: So that is a common question that I do get with my patients. So, I tell people, I'm here for you. And it really depends on how you feel at this time. Because you have to weigh the risks and benefits of the medication itself. If someone who's very, very mild decides to take the medication, they feel nauseous, they're just going to say, hey, listen, it's not for me right now. I don't feel like I need it, and then stop, which is with definitely within their right. But what I always counsel patients as well is to say, the dopamine-producing neurons in the substantia nigra are starting to die over time. That is why we are getting the signs and symptoms of Parkinson disease. At some point, your brain is not going to produce enough dopamine that is needed for you to move when you want to move and not move when you don't want to move. Okay? Giving you at least the motor symptoms of Parkinson disease. With this, it's not that the medication stops working, it's just that you need more dopamine to help replace the dopamine that's being lost. However, the dopamine that you are taking or levodopa that you're taking orally is not going to be released as consistently as it is in your brain on demand and shut off when you don't need it. Hence the reason we get more motor fluctuations. Also, potential side effects in the medication like orthostatic hypertension, hallucinations, impulse control disorders. Because you're having to take more escalating doses, those side effects can become more prominent and also lead us to have to balance between the side effects and the medication itself. So, it's not that the medication does not work, your body needs more of it. Some people will say, oh, well, I want to wait, and I say, that's completely fine. However, my cutoff is basically saying, if you are finding that you, as the person who's afflicted is not able to get up in the morning like you want to, you're avoiding going to walk your dog or working in your garden, you know, because you feel stiff and feel slow; you're avoiding, you know, going out to the community, having lunch with your friends or your family because you're embarrassed by your tremor; this is something that is keeping you from living your life. And that's the time that we need to strongly consider starting the medications. So, a person afflicted will accumulate deficits. However, it's how much the deficits are going to affect you. So, if it's really affecting your life, we have tools and ways to help mitigate that. Dr Nevel: Yeah, absolutely. Are there any aspects of Parkinson disease management that you feel are maybe underrecognized or perhaps underutilized? In other words, you know, are there things that we the listeners should be maybe more aware of or think about offering or recommending to our patients that you think maybe aren't as much as they could be? Dr Rawls: I will say the nonmotor symptoms---in particular the neuropsychiatric symptoms with the anxiety and depression, usually later on disease process but also can be earlier as well---I think that is going to be something that is recognized but maybe undertreated in a lot of our patient population. I think part of that is also the fluctuations in dopamine that are occurring naturally in the person, but also, our patients, oftentimes with their medication regimen, really have to be on the ball taking the medication. If they're even 15 minutes late, 10 minutes late, 5 minutes late, we're now off, and now we're waiting for it to kick in. And so that can cause a lot of anxiousness even throughout the day. And then knowing that slowly over time that they're going to accumulate these motor and nonmotor deficits can definitely be problematic as well. There is obvious reason for this underlying potential anxiety and depression. And while we do talk about that and bring that up, sometimes patients will say, oh well, I don't think it's a problem right now. I don't have to mess with this. But usually at some point it does become an issue that usually the family members will bring up and saying, hey, you know, my loved one is very anxious. Or I've noticed that they're just really disengaged from what's going on in their lives and they are not talking as much, they're not going out as much. Again, that could be a combination of depression/anxiety, but it also can be a physical- a combination of, I'm not physically able to do these things, or, they're much more difficult for me to initiate doing these activities. I always want to be mindful. If my patients come in and they already have a diagnosis of depression or anxiety and they're already being treated by a mental health counselor, provider, or a psychiatrist, then I will work with providers so that we can try to optimize their medication regimen. The other thing is, well, if this is the first time that they're really being seen by someone and talking about their anxiety and depression, then oftentimes I will have them go back to their primary care and see if maybe an SSRI or SNRI will be helpful to try to help with the neuropsychiatric symptoms they may be experiencing. So that's one big one. Another one that I think that might be a little bit underappreciated is going to be drooling. Sometimes I'll come in and see my patients and notice some drooling that's happening with the mouth being open, not being able to initiate the swallowing reflex consistently throughout the day. Or they may be patting their face a lot with a napkin or a towel and then bringing that up and bringing it to light. Oh yeah. I have a lot of drooling while I'm awake. It's on my shirt. It's embarrassing. I feel like it's a little bit too much for me or my family. We have to put a bib on because I'm just drooling all throughout the day. That can really be uncomfortable and cause skin breakdown. It can also be socially embarrassing. So, there are some tools that I talk to people about with drooling. One thing I start with is going to be using sugar-free gum or candy while the person is awake to help initiate the swallow reflex, and sometimes that's all that's needed. There are other agents that can be used---like glycopyrrolate, sublingual atropine drops, and scopolamine patches---that can help with decreasing saliva production. But there can be side effects of making the entire body feel dry, and then also potential cardiac arrhythmias. If those are not helpful or they're contraindicated with the patient, another thing is going to be botulinum toxin injections. So those can be done on the parotid and salivary glands to decrease the amount of saliva that's being produced. So oftentimes people will come to me, because I'm also a botulinum toxin injector. I've been sent by some of my colleagues to inject our persons that have significant sialorrhea. Dr Nevel: Wonderful. Well, thank you so much for chatting with me today about your article. Again, today I've been interviewing Dr Ashley Rawls about her article on Parkinson disease, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues. And thank you to our listeners for joining today. And thank you, Ashley, for sharing all your knowledge with us today. Dr Rawls: Thank you, Kate, I appreciate your time. And have a great day, everyone. Dr Monteith: This is Dr Teshmae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Episode SummaryIn this episode, Georgie Kovacs, founder of Fempower Health, unpacks the recent FDA hearing on SSRI use during pregnancy—an emotionally charged and complex conversation that brought together OB-GYNs, psychiatrists, pharmacologists, and advocates.Drawing on over 25 years in healthcare consulting and six years interviewing global women's health leaders, Georgie offers a balanced, deeply informed analysis of the real conversation that took place—beyond the headlines and controversy.This wasn't just a debate about antidepressants in pregnancy. It was a wider reckoning with how we define mental health, how we treat it, and the pressures facing clinicians and patients in a fragmented system. From risk-benefit tradeoffs and informed consent to how “depression” is diagnosed and operationalized, this episode explores what was said, what was missing, and what we need next.Whether you're a woman seeking clarity or a clinician striving to provide the best care, this episode breaks it all down.Discussion Points What actually happened at the FDA panel on SSRIs and pregnancy?Are SSRIs overprescribed—or unfairly stigmatized—during pregnancy?Is "depression" too broad of a diagnosis?How do mental health diagnoses affect treatment decisions for pregnant women?Why is informed consent inconsistent in SSRI prescribing?What are the long-term risks of untreated maternal depression?Are OB-GYNs expected to manage too much—including mental health?How does limited access to psychiatrists shape treatment options?What does better mental healthcare look like during pregnancy?Should we rethink how we integrate psychotherapy, medication, and lifestyle care?Expert Backgrounds MentionedOB-GYNs treating pregnant patients on SSRIsPsychiatrists both prescribing and deprescribing antidepressantsAcademic researchers investigating serotonin's effects on fetal developmentAdvocacy leaders spotlighting systemic barriers to mental health careResourcesFDA Hearing: https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-selective-serotonin-reuptake-inhibitors-ssris-and-pregnancy-07212025ACOG Response to FDA Hearing: https://www.acog.org/news/news-releases/2025/07/statement-on-benefit-of-access-to-ssris-during-pregnancySociety for Maternal-Fetal Medicine (SMFM) Statement https://www.smfm.org/news/smfm-statement-on-ssris-and-pregnancyRegulatory Focus Responds: https://www.raps.org/news-and-articles/news-articles/2025/7/fda-panel-debates-label-change-on-ssri-use-duringSTAT News Responds: https://www.statnews.com/2025/07/25/ssri-drugs-fda-review-panel-antidepressants-pregnancy/National Curriculum in Reproductive Psychiatry (NCRP) Responds: https://ncrptraining.org/press-release-ncrp-responds-to-fda-panel-on-ssri-use-in-pregnancy/

Mikki dives into the evolving science behind creatine—not just for muscles, but for brain health. Long known as a powerhouse for strength and performance, creatine is now gaining traction as a potential tool for cognitive enhancement and mental health support. Miki explores recent research shared by Dr. Nicholas Fabiano on creatine's potential role in improving outcomes in Alzheimer's, depression, and traumatic brain injury (TBI). She explains how higher doses may be required to impact brain creatine levels and discusses key findings around mood, cognition, and neurological recovery. Whether you're already taking creatine or considering it, this episode will broaden your understanding of how it could support not just your workouts, but your mental clarity and emotional well-being too.Highlights:Why creatine may support brain energy metabolism and cognitive functionEvidence for creatine's role in depression and SSRI-resistant casesHigh-dose creatine and its potential benefits in Alzheimer's and TBI recoveryDifferences in creatine needs between men and womenSafety considerations and dosing strategies for brain healthhttps://x.com/NTFabiano/status/1950155746034758119 Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

In 2005, Kim Crespi had what she later described as “the perfect life.” She and her husband, David—a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance—had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could bedestroyed in less than forty minutes. In January of 2006, while Kim was getting a haircut, Davidmurdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David had more questions than answers. In Medication, Mental Illness, and Murder, Edward L.Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries. Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mentalhealth systems, and of Big Pharma.EDWARD L. JONES III has been an award-winning writer in advertising and higher education. During his ad career, he won more than 350 awards for creativity. In his time away from advertising, Ed served as a community columnist for the Charlotte Observer. He lives in the Winston-Salem, North Carolina area. This is his first book.

I veckans odpod: Sport som SSRI, för snajdiga protagonister, det kulturindustriella komplexet och den kulturella platån. Om du kan, stöd oss på http://patreon.com/odpod

SSRI's Strike Again: 4 Dead in New York City After Lone Gunman Storms Blackstone BuildingLive Show Monday-Thursday, 3pm est.SOCIALS: https://linktr.ee/drewberquistNEWS: https://DrewBerquist.comMERCH: https://RedBeachNation.com#DrewBerquist #ThisIsMyShow #TIMSTop 100 Political News Podcast with https://www.millionpodcasts.com/political-news-podcasts/#1 Counterterrorism Podcast on Feedspot: https://podcast.feedspot.com/counter_terrorism_podcasts/Show Notes/Links:Trump signs EO to curb NIL and money in college sportshttps://x.com/premefootball/status/1948479059153092936NY Post headline day after shootinghttps://x.com/nypost/status/1950139161744117811Media described the shooter as white, or light skinnedhttps://x.com/autismcapital/status/1949991013138977120?s=46&t=uaL12_jzouHgBP9nzey-rghttps://x.com/ericldaugh/status/1949990259191697897?s=46&t=uaL12_jzouHgBP9nzey-rgNYC shooting timelinehttps://x.com/nicksortor/status/1950028665867137211Dems call for gun ban after NYC shootinghttps://x.com/westernlensman/status/1950022078091944324?s=46&t=uaL12_jzouHgBP9nzey-rgCincinnati Police Chief whines about social media in press conferencehttps://x.com/Babygravy9/status/19501250987923090815 charged in horrifying viral Cincinnati brawl that left woman knocked out cold https://x.com/Lukewearechange/status/1949949568067461446Pete Buttigieg: Trump is appointing "incompetent people" to serve in the governmenthttps://x.com/WesternLensman/status/1949935354011930830See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Tragedy in NYC. RFK Jr is looking into SSRI medications. See omnystudio.com/listener for privacy information.

A tragic shooting in NYC. RFK Jr. is investigating the use and safety of SSRI use for mental illnesses. The tragic assault of a couple in Cincinnati. Bill Maher flips his opinion on the tariffs. Does Eric Swalwell know what his job duties are? Should the legal driving age change? What about the legal drinking age? VP Vance talks BBB. Chuck Schumer is not a fan of the trade deal with the EU. See omnystudio.com/listener for privacy information.

Jefferey Jaxen returns with breaking coverage of a major shift at the FDA: for the first time, the agency is holding a public panel to investigate the dangers of SSRI drugs during pregnancy. Could this lead to a long-overdue black box warning?Meanwhile, FDA Commissioner Dr. Marty Makary makes a stunning admission—he personally knows people who have been injured or killed by the COVID-19 vaccine. As the U.S. barrels toward net zero policies and rapid AI expansion, America's energy grid faces unprecedented strain.Plus, don't miss our powerful and emotional interview with the Hammond family, who share their heartbreaking story of losing their daughter Malaya in the devastating Texas flood. Her final act of heroism saved her family. Their journey through grief, faith, and resilience will move and inspire you.Guests: Matthew & Liz HammondBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety. Find full show notes and links here: https://thethirdwave.co/podcast/episode-313b/?ref=278 Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work. If you're a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights. Highlights: How SSRIs blunt emotional range and alter awareness The neuroscience of serotonin and psychedelic receptors Serious risks of serotonin syndrome when mixing with SSRIs Ketamine's role in tapering and unlocking neuroplasticity Practical tools to regulate the nervous system during SSRI withdrawal Recommended psilocybin strains for sensitive or anxious clients How long-term SSRI use may (or may not) affect psychedelic response Safety-first protocols for psychedelic integration The future of microdosing as a sustainable antidepressant approach Episode Links: Dr. Dave Rabin's Website Dr. Dave on Instagram Dr. Dave on LinkedIn Apollo Neuro Last week's bonus episode with Dr. Robin Carhart-Harris: SSRIs vs. Psychedelics: From Blunting to Rebooting  Episode 218 with Dr. Dave Rabin Episode 74 with Dr. Dave Rabin Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute's Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More. Episode Sponsor: Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

The FDA recently held a panel on the safety of SSRI medications in pregnancy, which was uninformed and negatively impacts perinatal patients and their mental health. This episode discusses that scientifically inaccurate event. Resources:ACOG Statement on the FDA Panel: https://www.acog.org/news/news-releases/2025/07/statement-on-benefit-of-access-to-ssris-during-pregnancy To learn more about me and my reproductive & integrative psychiatry clinic helping patients across California, please visit - AnnaGlezerMD.comTo sign up for the Fellowship in Reproductive & Integrative Psychiatry, please visit:  PsychiatryFellowship.com. 

A life marked by pain, addiction, and spiritual warfare can feel like a dead end. Substance abuse, anxiety, and demonic oppression often isolate people in cycles of shame and confusion. Many find themselves desperate for freedom, yet unsure how to break the chains that hold them back. The battle is not only physical and emotional, it's spiritual. And it often takes something greater than willpower to escape it: a divine encounter.In this episode of Revelations Podcast, host Reagan Kramer sits down with Tommy Doyle. He is the International Director of Uncharted Ministries and son of renowned missionary leaders Tom and Joanne Doyle. Tommy takes us on a riveting journey from being a pastor's kid entangled in alcoholism, panic attacks, and spiritual torment, to becoming a frontline missionary reaching war zones in the Middle East with the love of Christ. His battles with demonic forces and deliverance through a divine encounter of Jesus offer a powerful message of hope for anyone navigating the wilderness of addiction or doubt.Be equipped with spiritual tools to confront addiction, anxiety, and spiritual warfare with the authority of Jesus. This episode is for hurting hearts, wandering believers, and anyone ready to trade despair for lasting freedom in Christ.Here are three reasons why you should listen to this episode:Discover the spiritual component of addiction and how it can be broken through a divine encounter with Jesus.Explore the reality of spiritual warfare in regions like Egypt and how prayer activates victory over darkness.Learn how Tommy's story shows hope for those battling both anxiety and faith deconstruction.Become Part of Our Mission! Support The Revelations Podcast:Your support fuels our mission to share transformative messages of hope and faith. Click here to learn how you can contribute and be part of this growing community!ResourcesMore from the Revelations Podcast hosted by Reagan Kramer: Website | Instagram | Apple Podcast | YoutubeUncharted Ministries: WebsiteUncharted Adventures: Website“Dreams and Visions: Is Jesus Awakening the Muslim World?” by Tom Doyle“Women Who Risk” by Tom and Joanne Doyle“Spiritual Warfare: Christians, Demonization, and Deliverance” by Dr. Karl Payne Bible Verses2 Timothy 1:7This Episode is brought to you by Advanced Medicine AlternativesGet back to the active life you love through natural & regenerative musculoskeletal healing: https://www.georgekramermd.com/Episode Highlights[00:36] Freedom from Addiction and the Fight for the SoulAddiction, anxiety, and spiritual warfare can make people feel trapped and unseen.Many silently battle overwhelming darkness, believing healing is out of reach.Tommy Doyle, International Director of Uncharted Ministries, knows this struggle firsthand.[03:21] Tommy: “We have so many good friends and so many ministry partners over there, that that's just really where our heart was, and we were part of another ministry before that that we loved dearly, so many great people and everything.”Once bound by addiction and anxiety, Tommy now leads missions that bring healing and hope across the Middle East.[05:26] Ministry Work in the Middle EastTommy describes Uncharted Ministries' work across war-torn regions of the Middle East.He recalls visiting the Gaza Strip a month after a major attack, wearing flak jackets and traveling with armed EMTs.Despite the chaos, they shared comfort and reminded hurting communities that they are not forgotten.Through every mission, Tommy emphasizes the power of showing up and bringing the love of Christ.[12:19] Personal Testimony and Early LifeTommy grew up in a large Christian family, deeply involved in church life as a pastor's kid.Despite strong early faith, he experienced rejection and betrayal from peers in church leadership.That emotional wound led him to pull away and seek belonging in sports and party culture.This shift laid the groundwork for his eventual descent into substance use and spiritual drift.[24:23] Struggles with Addiction and Turning PointTommy began justifying casual partying, which escalated into drug dealing and daily alcohol use.A raid by federal agents became a wake-up call, but the pull of addiction remained strong.Panic attacks worsened his condition, and alcohol became his go-to form of self-medication.Despite several attempts to quit, nothing brought lasting freedom—until he cried out to God.[26:42] Egypt Mission Trip and Spiritual AwakeningTommy joined a mission trip to Egypt to support his mother's outreach to Muslim women.While caring for children there, he was struck by a deep conviction to return to a life of purpose.That moment reignited his faith, shifted his focus, and set him on a path of full sobriety.He returned home and committed to healing through a Christ-centered Celebrate Recovery program.[36:11] Supernatural Encounter in EgyptDuring a foot-washing ceremony, Tommy witnessed a woman visibly possessed and delivered through the name of Jesus.[39:47] Tommy: “Every time that something dark and scary would happen, witnessed by other people too, the power of the name of Jesus was enough to eradicate it and, and that's just so life-giving.”Later that night, he and his brother encountered a terrifying demonic presence outside their desert compound.Prayer in Jesus' name broke the oppression, revealing that when the demonic and divine encounter each other, the authority of Christ prevails over darkness.These spiritual battles confirmed the reality of unseen warfare—and the power believers carry.[47:49] Territorial Spirits and the Battle Over RegionsTommy and Reagan reflect on how demonic strongholds operate not just personally, but over entire regions.In spiritually charged areas like the Middle East, the Enemy fiercely resists gospel work.Tommy shares how even Bible translation efforts in unreached areas face constant spiritual interference.Yet through it all, God's power continues to break ground where darkness has long ruled.[52:45] The Link Between Medication and AddictionTommy discusses the role anti-anxiety medication played in intensifying his alcohol cravings.He noticed his dependence on alcohol spiked after starting an SSRI prescribed for panic attacks.This connection led him to research and ultimately discontinue the medication after his spiritual breakthrough.He encourages others to evaluate their health journeys prayerfully and seek Spirit-led guidance.[58:39] Advice for Overcoming Addiction and AnxietyTommy urges listeners to admit powerlessness and seek a divine encounter with Jesus as the first step to healing.By trusting Him, we take a faithful path to healing.He shares practical advice for managing anxiety, including diet, outdoor activity, and community support.Accountability and honesty are key—especially with trusted friends and family.Above all, he emphasizes that true freedom from addiction and fear comes through Christ alone.[1:03:43] Tommy: “I did not need a foreign substance to be happy and enjoy life. And that's such a lie if, if that's holding you back, reconnect with the Lord.”[1:05:52] Living Free From Darkness to Purpose in ChristTommy reminds listeners that surrender is not weakness but the beginning of real strength.He shares how 2 Timothy 1:7 has anchored him through fear and addiction.God's healing is available to anyone ready to leave darkness and walk into His light.Learn more about Tommy's work through Uncharted Ministries and Uncharted Adventures at unchartedministries.com.About Tommy DoyleTommy Doyle is a missionary leader, speaker, and redeemed overcomer called to bring light into the darkest places. As the International Director of Uncharted Ministries, he continues the legacy of his parents, Tom and Joanne Doyle, by leading gospel-centered outreach in the Middle East and beyond. From war zones to remote villages, Tommy helps bring humanitarian aid, spiritual support, and the message of Jesus to those living in fear, trauma, or persecution. His work bridges cultures and faiths, demonstrating the power of God's love across some of the most spiritually resistant regions in the world.Once bound by addiction, anxiety, and demonic oppression, Tommy experienced radical deliverance during a divine encounter. On his mission trip to Egypt, he reignited his faith and reshaped his purpose. Now over a decade sober, he uses his testimony to reach those walking through their own wilderness. With firsthand experience in spiritual warfare and recovery, Tommy equips others to confront addiction, overcome fear, and live with bold, Christ-centered purpose. His story is a powerful reminder that no one is too far gone for the grace of God.Connect with Tommy through the Uncharted Ministries website.Enjoyed this Episode?If you did, subscribe and share it with your friends!Post a review and share it! If you enjoyed tuning in about generational curses and how to break them, leave us a review. You can also share this with your friends and family. Freedom from addiction, anxiety, and spiritual oppression begins with surrender. When you experience a divine encounter with Jesus, darkness loses its grip. Let this be a reminder that no matter how far you've gone, healing and purpose are still possible.Have any questions? You can connect with me on Instagram.Thank you for tuning in! For more updates, tune in on Apple Podcasts

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In this episode of The Psychedelic Podcast, Paul F. Austin is joined by renowned neuroscientist Dr. Robin Carhart-Harris and microdosing policy advocate John Downs for a replay of a live event originally held on June 10th, Microdosing vs. SSRIs: What's Happening in the Brain and Why It Matters. Find full show notes and links here: https://thethirdwave.co/podcast/episode-312b/?ref=278 Together, they explore the scientific distinctions between SSRIs and psychedelics, focusing on neuroimaging, brain entropy, emotional processing, and the REBUS model. Dr. Carhart-Harris shares key insights from landmark studies on psilocybin therapy and discusses the evidence (and limitations) around microdosing. John Downs closes the conversation with an update on the Microdosing Collective's efforts to shift policy and expand access. Robin Carhart-Harris, PhD is a neuropharmacologist, psychologist, and Ralph Metzner Distinguished Professor in Neurology and Psychiatry at the University of California, San Francisco. He leads the Psychedelics Division at UCSF's Neuroscape and formerly founded and led the Centre for Psychedelic Research at Imperial College London. John Downs is Executive Director of the Microdosing Collective, advocating for responsible policy reform and legal access to microdosing. With 25 years' experience in sales, business development, and emerging markets, John helps individuals optimize mindset, performance, and purpose. Episode Highlights: Why SSRIs blunt, while psychedelics reset emotional processing How psilocybin compares to antidepressants in clinical trials Brain entropy, plasticity, and the REBUS model explained The role of the default mode network in mental health Why microdosing research is still so limited Ketamine vs. psilocybin: differences in brain mechanisms Is serotonin syndrome a real microdosing risk? Can psychedelics reverse long-term SSRI effects? The Microdosing Collective's mission for policy reform What Robin Carhart-Harris' upcoming book will explore Episode Links: Robin's lab & upcoming book Microdosing Collective Join Dr. Robin Carhart-Harris at our Practitioner Intensive (November 5–10, Costa Rica) Episode Sponsors: Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout Psychedelic Coacing Isntitute's  Intensive for Psychedelic Professionals in Costa Rica - a transformative retreat for personal and professional growth.

Episode 198: Fatigue.  Future doctors Redden and Ibrahim discuss with Dr. Arreaza the different causes of fatigue, including physical and mental illnesses. Dr. Arreaza describes the steps to evaluate fatigue. Some common misconceptions are explained, such as vitamin D deficiency and “chronic Lyme disease”. Written by Michael Ibrahim, MSIV, and Jordan Redden, MSIV, Ross University School of Medicine. Edits and comments by Hector Arreaza, MDYou are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Dr. Arreaza: Today is a great day to talk about fatigue. It is one of the most common and most complex complaints we see in primary care. It involves physical, mental, and emotional health. So today, we're walking through a case, breaking down causes, red flags, and how to work it up without ordering the entire lab catalog.Michael:Case: This is a 34-year-old female who comes in saying, "I've been feeling drained for the past 3 months." She says she's been sleeping 8 hours a night but still wakes up tired. No recent illnesses, no weight loss, fever, or night sweats. She denies depression or anxiety but does report a lot of work stress and taking care of her two little ones at home. She drinks 2 cups of coffee a day, doesn't drink alcohol, and doesn't use drugs. No medications, just a multivitamin. Regular menstrual cycles—but she's noticed they've been heavier recently.Jordan:Fatigue is a persistent sense of exhaustion that isn't relieved by rest. It's different from sleepiness or muscle weakness.Classification based on timeline:    •   Acute fatigue: less than 1 month    •   Subacute: 1 to 6 months    •   Chronic: more than 6 monthsThis patient's case is subacute—going on 3 months now.Dr. Arreaza:And we can think about fatigue in types:    •   Physical fatigue: like muscle tiredness after activity    •   Mental fatigue: trouble concentrating or thinking clearly (physical + mental when you are a medical student or resident)    •    Pathological fatigue: which isn't proportional to effort and doesn't get better with restAnd of course, there's chronic fatigue syndrome, also called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), which is a diagnosis of exclusion after 6 months of disabling fatigue with other symptoms.Michael:The differential is massive. So, we can also group it by systems.Jordan:Let's run through the big ones.Endocrine / Metabolic Causes    • Hypothyroidism: A classic cause of fatigue. Often associated with cold intolerance, weight gain, dry skin, and constipation. May be subtle and underdiagnosed, especially in women.    • Diabetes Mellitus: Both hyperglycemia and hypoglycemia can cause fatigue. Look for polyuria, polydipsia, weight loss, or blurry vision in undiagnosed diabetes.    • Adrenal Insufficiency: Think of this when fatigue is paired with hypotension, weight loss, salt craving, or hyperpigmentation. Can be primary (Addison's) or secondary (e.g., due to long-term steroid use).Michael: Hematologic Causes    • Anemia (especially iron deficiency): Very common, especially in menstruating women. Look for fatigue with pallor, shortness of breath on exertion, and sometimes pica (craving non-food items).     • Vitamin B12 or Folate Deficiency: B12 deficiency may present with fatigue plus neurologic symptoms like numbness, tingling, or gait issues. Folate deficiency tends to present with megaloblastic anemia and fatigue.    • Anemia of Chronic Disease: Seen in patients with chronic inflammatory conditions like RA, infections, or CKD. Typically mild, normocytic, and improves when the underlying disease is treated.Michael: Psychiatric Causes    • Depression: A major driver of fatigue, often underreported. May include anhedonia, sleep disturbance, appetite changes, or guilt. Sometimes presents with only somatic complaints.    • Anxiety Disorders: Mental fatigue, poor sleep quality, and hypervigilance can leave patients feeling constantly drained.    • Burnout Syndrome: Especially common in caregivers, healthcare workers, and educators. Emotional exhaustion, depersonalization, and reduced personal accomplishment are key features.Jordan: Infectious Causes    • Epstein-Barr Virus (EBV):Mononucleosis is a well-known cause of fatigue, sometimes lasting weeks. May also have sore throat, lymphadenopathy, and splenomegaly.    • HIV:Consider it in high-risk individuals. Fatigue can be an early sign, along with weight loss, recurrent infections, or night sweats.    • Hepatitis (B or C):Can present with chronic fatigue, especially if liver enzymes are elevated. Screen at-risk individuals.    • Post-viral Syndromes / Long COVID:Fatigue that lingers for weeks or months after viral infection. Often, it includes brain fog, muscle aches, and post-exertional malaise.Important: Chronic Lyme disease is a controversial term without a consistent clinical definition and is often used to describe patients with persistent, nonspecific symptoms not supported by objective evidence of Lyme infection. Leading medical organizations reject the term and instead recognize "post-treatment Lyme disease syndrome" (PTLDS) for persistent symptoms following confirmed, treated Lyme disease, emphasizing that prolonged antibiotic therapy is not effective. Research shows no benefit—and potential harm—from extended antibiotic use, and patients with unexplained chronic symptoms should be thoroughly evaluated for other possible diagnoses.Michael: Cardiopulmonary Causes    •   Congestive Heart Failure (CHF): Fatigue from poor perfusion and low cardiac output. Often comes with dyspnea on exertion, edema, and orthopnea.    •   Chronic Obstructive Pulmonary Disease (COPD): Look for a smoking history, chronic cough, and fatigue from hypoxia or the work of breathing.    •   Obstructive Sleep Apnea (OSA): Daytime fatigue despite adequate hours of sleep. Patients may snore, gasp, or report morning headaches. High suspicion in obese or hypertensive patients.Jordan:Autoimmune / Inflammatory Causes    •   Systemic Lupus Erythematosus (SLE): Fatigue is often an early symptom. May also see rash, arthritis, photosensitivity, or renal involvement.    •   Rheumatoid Arthritis (RA): Fatigue from systemic inflammation. Morning stiffness, joint pain, and elevated inflammatory markers point to RA.    •   Fibromyalgia: A chronic pain syndrome with widespread tenderness, fatigue, nonrestorative sleep, and sometimes cognitive complaints ("fibro fog").Cancer / Malignancy    •   Leukemia, lymphoma, or solid tumors: Fatigue can be the first symptom, often accompanied by weight loss, night sweats, or unexplained fevers. Consider when no other cause is evident.Michael:Medications:Common culprits include:    ◦   Beta-blockers: Can slow heart rate too much.    ◦   Antihistamines: Sedating H1 blockers like diphenhydramine.    ◦   Sedatives or sleep aids: Can cause grogginess and daytime sedation.    •   Substance Withdrawal: Fatigue can be seen in withdrawal from alcohol, opioids, or stimulants. Caffeine withdrawal, though mild, can also contribute.Dr. Arreaza:Whenever we evaluate fatigue, we need to keep an eye out for red flags. These should raise suspicion for something more serious:    •   Unintentional weight loss    •   Night sweats    •   Persistent fever    •   Neurologic symptoms    •   Lymphadenopathy    •   Jaundice    •   Palpitations or chest painThis patient doesn't have these—but that doesn't mean we stop here.Dr. Arreaza:Those are a lot of causes, we can evaluate fatigue following 7 steps:Characterize the fatigue.Look for organic illness.Evaluate medications and substances.Perform psychiatric screening.Ask questions about quantity and quality of sleep.Physical examination.Undertake investigations.So, students, do we send the whole lab panel?Michael:Not necessarily. Labs should be guided by history and physical. But here's a good initial panel:    •   CBC: To check for anemia or infection    • TSH: Screen for hypothyroidism    • CMP: Look at electrolytes, kidney, and liver function    • Ferritin and iron studies    • B12, folate    • ESR/CRP for inflammation (not specific)    • HbA1c if diabetes is on the radarJordan:And if needed, consider:    • HIV, EBV, hepatitis panel    • ANA, RF    • Cortisol or ACTH stimulation testImaging? Now that's rare—unless there are specific signs. Like chest X-ray for possible cancer or TB, or sleep study if you suspect OSA.Dr. Arreaza:Unaddressed fatigue isn't just inconvenient. It can impact on quality of life, affect job performance, lead to mood disorders, delay diagnosis of serious illness, increase risk of accidents—especially driving. So, don't ignore your patients with fatigue!Jordan:And some people—like women, caregivers, or shift workers—are especially at risk.Michael:The cornerstone of treatment is addressing the underlying cause.Jordan:If it's iron-deficiency anemia—treat it. If it's depression—get mental health involved. But there's also: Lifestyle Support: Better sleep hygiene, light physical activity, mindfulness or CBT for stress, balanced nutrition—especially iron and protein, limit caffeine and alcoholDr. Arreaza:Sometimes medications help—but rarely. And for chronic fatigue syndrome, the current best strategies are graded exercise therapy and CBT, along with managing specific symptoms. Beta-alanine has potential to modestly improve muscular endurance and reduce fatigue in older adults, but more high-quality research is needed.SSRI: fluoxetine and sertraline. Iron supplements: Even without anemia, but low ferritin [Anecdote about low ferritin patient]Jordan:This case reminds us to take fatigue seriously. In her case, it may be multifactorial—work stress, caregiving burden, and possibly iron-deficiency anemia. So, how would we wrap up this conversation, Michael?Michael:We don't need to order everything under the sun. A focused history and exam, targeted labs, and being alert to red flags can guide us.Jordan:And don't forget the basics—sleep, stress, and nutrition. These are just as powerful as any prescription.Dr. Arreaza:We hope today's episode on fatigue has given you a clear framework and some practical tips. If you enjoyed this episode, share it and subscribe for more evidence-based medicine!Jordan:Take care—and get some rest~___________________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:DynaMed. (2023). Fatigue in adults. EBSCO Information Services. https://www.dynamed.com (Access requires subscription)Jason, L. A., Sunnquist, M., Brown, A., Newton, J. L., Strand, E. B., & Vernon, S. D. (2015). Chronic fatigue syndrome versus systemic exertion intolerance disease. Fatigue: Biomedicine, Health & Behavior, 3(3), 127–141. https://doi.org/10.1080/21641846.2015.1051291Kroenke, K., & Mangelsdorff, A. D. (1989). Common symptoms in ambulatory care: Incidence, evaluation, therapy, and outcome. The American Journal of Medicine, 86(3), 262–266. https://doi.org/10.1016/0002-9343(89)90293-3National Institute for Health and Care Excellence. (2021). Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: Diagnosis and management (NICE Guideline No. NG206). https://www.nice.org.uk/guidance/ng206UpToDate. (n.d.). Approach to the adult patient with fatigue. Wolters Kluwer. https://www.uptodate.com (Access requires subscription)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

In this explosive and highly anticipated episode, Dr. Roger McFillin hosts Dr. Ragy Girgis, a Columbia University Professor of Psychiatry and researcher, for a no-holds-barred confrontation that exposes the shocking divisions tearing apart the mental health field. What begins as a conversation about mass violence research rapidly explodes into a devastating examination of psychiatric medicine's crumbling foundations, questionable effectiveness, and devastating potential harms. The two clash in fierce, unrelenting disagreements over fundamental issues including the validity of DSM diagnoses, the debunked "chemical imbalance" theory of depression, dangerous SSRI safety cover-ups and black box warnings, corrupted research quality and pharmaceutical industry manipulation, and the catastrophic crisis of psychiatric drug overprescription poisoning 1 in 4-5 Americans. Dr. Girgis desperately defends traditional academic psychiatry and current treatment approaches, while Dr. McFillin ruthlessly dismantles the entire paradigm, arguing that the current system is systematically creating chronic mental illness rather than healing it. Buckle up for this brutal intellectual warfare.___________________________________________________________________________________________________________________________________________________Throughout the interview, Dr. Girgis repeatedly stated that "the data is clear" while dismissing contradictory evidence that challenges his conclusions. For our listeners' benefit, I have compiled research and documentation that directly disputes several of Dr. Girgis's key claims.Serotonin Hypothesis of Depression1. The serotonin theory of depression: a systematic umbrella review of the evidence (Moncrieff et al.)Conclusions: "This review suggests that the huge research effort based on the serotonin hypothesis has NOT produced convincing evidence of a biochemical basis to depression. This is consistent with research on many other biological markers . We suggest it is time to acknowledge that the serotonin theory of depression is NOT empirically substantiated."2.What has serotonin to do with depression?Conclusions: "Simple biochemical theories that link low levels of serotonin with depressed mood are no longer tenable."3. Is the chemical imbalance an ‘urban legend'? An exploration of the status of the serotonin theory of depression in the scientific literatureViolence & Suicide Associated with SSRI's 1. Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers2. Prescription Drugs Associated with Reports of Violence Towards Others3. Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family4. Lexapro Approved for Pediatric Use Despite the 6-Fold Increase in Suicide Risk5. McFillin Substack Review on Lexapro approved despite Suicide Risk6. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports7. Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect8. Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk:9.  FDA Warning: Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents10.  Suicide Mortality in the United States, 2001–2021 CDC documentation11. US suicide rate reaches highest point in more than 80 years: See what latest data shows12.  CNN article reporting Eli Lilly Internal Documents"An internal document purportedly from Eli Lilly and Co. made public Monday appears to show that the drug maker had data more than 15 years ago showing that patients on its antidepressant Prozac were far more likely to attempt suicide and show hostility than were patients on other antidepressants and that the company attempted to minimize public awareness of the side effects. The 1988 document indicated that 3.7 percent of patients attempted suicide while on the blockbuster drug, a rate more than 12 times that cited for any of four other commonly used antidepressants.In addition, the paper said that 1.6 percent of patients reported incidents of hostility -- more than double the rate reported by patients on any of four other commonly used antidepressants."Examples of Violence after Prescription in legal system (Sample)January 24, 2020 – Newcastle, South Dublin, Ireland: Deirdre Morley, 44, smothered and killed her two sons Conor, 9, and Darragh, 7, and her three-year-old daughter Carla McGinley in their family home. She had been taking antidepressants since October 2018 and was admitted to St. Patrick's Mental Health Services on July 6, 2019, but was discharged after a short period, but was put on a combination of two antidepressants and a sedativeMay 11, 2018 – Osmington, Western Australia: Peter Miles, 61, shot his 35-year-old daughter and four grandchildren, aged 8 through 13, while they slept in their beds, in a shed that had been converted to a second house on the property. He then turned the gun on his 58-year-old wife in the living room of their house, before placing a call to police alerting them to his crimes. When they arrived, Miles was also found dead from a gunshot wound. Miles had started taking antidepressant medication just weeks before.April 6, 2018 – Wadsworth, Ohio: Gavon Ramsay, 17, strangled his neighbor, 98-year-old Margaret Douglas in her own home. His parents blame his actions on his having been misprescribed Zoloft. After a report by his school principal that the teen was depressed and might harm himself, he “returned to therapy,” and after a recommendation by a psychologist, the family's pediatrician prescribed the antidepressant Zoloft. From January through March leading up to the incident, the dosages were increased. During this time, his mother said she observed her son's behavior change—becoming increasingly irritable and hostile and saying bizarre things.October 21, 2013 – Sparks, Nevada: 12-year-old Jose Reyes opened fire at Sparks Middle School, killing a teacher and wounding two classmates be...

In this episode, Seth Mehr, MD joins to share his expertise on safety planning prior to a patient undergoing psilocybin therapy. After a 20 year career as an Emergency Medicine physician, Seth founded Cascade Psychedelic Medicine in 2021, treating clients with depression, anxiety and PTSD with psychedelic ketamine therapy. He also serves as the Health & Safety Director and a state licensed psilocybin facilitator at the Innertrek service center in Portland, Oregon. In this conversation, Dr. Mehr outlines key risk categories for psilocybin therapy: medical conditions, medication interactions, and mental health history. He emphasizes the importance of individualized safety planning over binary yes/no decisions. Dr. Mehr discusses specific considerations such as cardiovascular issues, diabetes, serotonergic medications, substance use disorders, suicidal ideation, and family history of psychosis. The conversation also covers strategies for mitigating risk, including delaying treatment, contingency plans, improving support systems, and ensuring informed consent. Throughout, Dr. Mehr stresses a collaborative, nuanced approach that balances potential benefits with careful preparation and personalized care.   In this episode, you'll hear: Stories from Dr. Mehr's practice of helping patients with different conditions and histories ensure safe psilocybin experiences Interactions between GLP-1 agonists and psilocybin How Dr. Mehr works with patients who have family histories of psychosis Harm reduction practices which leverage other psychedelics or non-psychedelic interventions to help prepare a client for a psilocybin session Why insulin dependent diabetes can be a contraindication for psychedelic therapy What medication combinations can increase the risk of serotonin toxicity with psilocybin  Supporting clients experiencing spiritual emergency following psilocybin therapy Safety considerations when working with clients who have a history of seizures The importance of having contingency plans if medical emergencies arise during psilocybin therapy The intricacies of providing fully informed consent for psychedelic therapy   Quotes: “There is some evidence now that taking a single serotonergic agent—say, taking Lexapro—and no other medications that increase the risk of serotonin toxicity seems safe where I am not at this point recommending that people stop, skip, or taper a single SSRI in preparation for a psilocybin session due to safety.” [12:20] “One of the difficulties with making these decisions or speaking with some confidence or authority on the matter is that the clinical trials that have been done largely exclude people with lots of conditions—family history and specifically first degree relatives with history of psychosis and bipolar disorder… So we have anecdotal evidence, we have population based surveys to go by. And so when I talk to clients about this, I speak from a place of humility.” [27:30] “I always emphasize to clients that while we're talking about a specific safety issue like serotonin toxicity, we don't want to trade that for psychological instability and crisis and declare success because we've helped somebody taper off of a medication that seems less safe and now they aren't sleeping, they're agitated, they're depression is worse, their suicidality is worse. So we have to take a holistic approach to this and consider the totality of what's happening with that client.”  [36:45] “There are so many different components to trying to set somebody up for success rather than a yes/no, black and white approach [to psilocybin therapy].” [48:44]   Links: Cascade Psychedelic Medicine website InnerTrek website Managing Medical Risk In Patients Seeking Psilocybin Therapy CME/CE Course Psychedelic Medicine Association Porangui  

Emily Grey's been living with a condition known as PSSD for six years now. PSSD can lead to the effective erasure of a person's sexual sensation and functioning.The SSRIs that seem to be at the heart of this condition are selective serotonin uptake inhibitors, a group of antidepressant drugs that have been around for decades. The latest numbers indicate that nearly 20% of Canadian women and 10% of Canadian men are now taking these drugs. It is generally known that potential side effects include a loss of libido. But what we're talking about today and what advocates like Emily have been saying for years is that the side effects can be very extreme. They might persist even after you stop taking SSRIs.We'll also be speaking with Dr. David Healy, a professor of psychiatry at the University of Cardiff in Wales. Dr. Healy has been involved in SSRI research for decades. He's the author of over a dozen books on psychopharmacology, including Let Them Eat Prozac, the Unhealthy Relationship Between The Pharmaceutical Industry and Depression.Also on our panel is Dr. Caroline Pukall professor of psychology at Queen's University whose research focuses on sexual wellbeing and includes sexual psychophysiology.Credits: Host: Jesse BrownCaleb Thompson (Audio Editor), Bruce Thorson (Senior Producer), max collins (Director of Audio), Jesse Brown (Editor and Publisher)Fact checking by Julian AbrahamAdditional music by Audio NetworkFurther ReadingPSSD websiteDr. David HealyDr. Caroline PukallSponsors: oxio: Head over to canadaland.oxio.ca and use code CANADALAND for your first month free! Article: Article is offering our listeners $50 off your first purchase of $100 or more. To claim, visit article.com/canadaland and the discount will be automatically applied at checkoutBetterHelp: Visit betterHelp.com/canadaland today to get 10% off your first month.If you value this podcast, support us! You'll get premium access to all our shows ad free, including early releases and bonus content. You'll also get our exclusive newsletter, discounts on merch at our store, tickets to our live and virtual events, and more than anything, you'll be a part of the solution to Canada's journalism crisis, you'll be keeping our work free and accessible to everybody. You can listen ad-free on Amazon Music—included with Prime. Hosted on Acast. See acast.com/privacy for more information.

Social Security Retirement Income has some good news–no kidding–and we invite expert Chad Harmon to discuss the details. Previously, public pensioners like government employees, schoolteachers, police officers, firefighters and more, received either no Social Security Retirment Income or had their benefits severely reduced. Now, they can earn more. Learn who this affects, how much it affects them, and how you or someone you love could benefit.2.5 to 3 million may benefit from SSRI improvements. Who will benefit the most? What might you be able to do to take advantage of these additional benefits? And check in at the end to know what you may need to do if you have never bothered to register with the SSRI in the past.As a quick reminder, the Expert Network Team provides free consultations. We would love the opportunity to be of service to you or someone you care about. Just scroll the liner notes to contact one of our experts or today's guest. And please share this podcast with anyone who you think might find it interesting.As always, it is good to have an expert on your side.— Our guest:Chad HarmonPartner, A&I Wealth Management(303) 690.5070chad@assetsandincome.com Expert Network team provides free consultations. Just mention that you listened to the podcast. Nathan Merrill, attorneyWorking with affluent families and entrepreneurs in implementing tax-efficient strategies and wealth preservationGoodspeed, Merrill(720) 473-7644nmerrill@goodspeedmerrill.comwww.goodspeedmerrill.com Jeff Krommendyk, Insurance ExpertWorking with business owners and successful families in transferring riskOne Digital Insurance Agency(303) 730-2327jeff.krommendyk@onedigital.com Karl FrankFinancial planner helping a small number of successful families grow and protect their wealth and choose how they want to be taxedCERTIFIED FINANCIAL PLANNER™A&I Wealth Management(303) 690.5070karl@assetsandincome.com Webcasts, Podcasts, Streaming Video, Streaming AudioA&I webcasts, podcasts, streaming video, or streaming audios are provided free of charge solely for use by individuals for personal, noncommercial uses, and may be downloaded for such uses only, provided that the content is not edited or modified in any way and provided that all copyright and other notices are not erased or deleted.All webcasts, podcasts, streaming video, or streaming audios are subject to and protected by U.S. and international copyright laws and may not be sold, edited, modified, used to create new works, redistributed or used for the purpose of promoting, advertising, endorsing or implying a connection with A&I.A&I reserves the right, at any time and for any reason, to stop offering webcasts, podcasts, streaming video, or streaming audios and to stop access to or use of webcasts, podcasts, streaming video, or streaming audio and any content contained therein A&I shall not be liable for any loss or damage suffered as a result of, or connected with, the downloading or use of the webcasts, podcasts, streaming video, or streaming audios. A&I Wealth Management is a registered investment adviser that only conducts business in jurisdictions where it is properly registered, or is excluded or exempted from registration requirements. Registration as an investment adviser is not an endorsement of the firm by securities regulators and does not mean the adviser has achieved a specific level of skill or ability. The firm is not engaged in the practice of law or accounting.The information presented is believed to be current. It should not be viewed as personalized investment advice. All expressions of opinion reflect the judgment of the presenter on the date of the podcast and are subject to change. The information presented is not an offer to buy or sell, or a solicitation of any offer to buy or sell, any of the securities discussed. You should consult with a professional adviser before implementing any of the strategies discussed. Any legal or tax information provided in this podcast is general in nature. Always consult an attorney or tax professional regarding your specific legal or tax situation.

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Dr. Adam Urato grew up in Framingham, Massachusetts—and returned to serve the same hospital he was born in. But over the course of his career as a maternal-fetal medicine specialist, he discovered a troubling truth: much of what passes for “standard of care” in obstetrics isn't grounded in good science—it's driven by pharmaceutical profit.In this gripping episode, Dr. Urato unpacks the decades-long use of Makena, a drug prescribed to prevent preterm birth that was ultimately pulled after being proven ineffective. He details how the same pattern of flawed trials, exaggerated benefits, and minimized risks is playing out again with SSRI use during pregnancy—putting fetal brain development at risk without informed consent.Together with hosts Drs. May and Tim Hindmarsh, Dr. Urato questions the systems that keep patients in the dark, the media silenced, and doctors bound by legal handcuffs to outdated protocols. He reminds us that medications are chemicals—and chemicals have consequences, especially during pregnancy.If you've ever trusted a prescription without questioning where the science really comes from, this episode might just change the way you see modern medicine.Our Advice!Everything in this podcast is for educational purposes only. It does not constitute the practice of medicine and we are not providing medical advice. No Physician-patient relationship is formed and anything discussed in this podcast does not represent the views of our employers. The Fine Print!All opinions expressed by the hosts or  guests in this episode are solely their opinion and are not to be used as specific medical advice.  The hosts,  May and Tim Hindmarsh MD, BS Free MD LLC, or any affiliates thereof are not under any obligation to update or correct any information provided in this episode. The guest's statements and opinions are subject to change without notice.Thanks for joining us! You are the reason we are here.  If you have questions, reach out to us at doc@bsfreemd.com or find Tim and I on Facebook and IG.Please check out our every growing website as well at  bsfreemd.com (no www) GET SOCIAL WITH US!We're everywhere here: @bsfreemd 

This episode originally aired as #327 on 5/20/23. It's an oldie but goodie so we are sharing it again! Mental Health is a mounting issue in America today.  Pharma prescriptions are higher than ever before, more people are in therapy than ever before and more than ever, people are searching for alternatives to those methods. On today's episode Jared runs through what he considers to be the foundational things that you should consider to improve your mental health. You will learn about the gut brain connection, deficiencies that impact mental health, the value of breath, sleep, water,  sunshine and more.Products:Precision Probiotic Vital SporesVital 5 Magnesium BisglycinateVital 5 Ultimate Vitality Multi-VitaminBioCoenzymated Active B ComplexVital 5 Omega 3 + AntioxidantsUltra Strength RX Omega 3Sensoril AshwagandhaAnxiety ReleaseVital SleepL-Theanine chewables Additional Information:Episode #164: Psychobiotics - Unique Probiotics for Depression, Anxiety and More Part 1Episode #166: Psychobiotics - Unique Probiotics for Depression Anxiety and More Part 2Episode #306: The Great Debate in Probiotics: Human Strains vs. SporesEpisode #258: Your Magnesium Users GuideEpisode #264: Jen's Story: How One Woman Fought Through Addiction, Mental and Physical Illness to Find Vitality.Episode #265: Sleep! Your Guide to Falling Asleep, Staying Asleep and Deeper and More Restful SleepVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

Methylene Blue has been getting a lot of attention lately, and I wanted to cut through the noise with some real science. I sat down with my friend Dr. Scott to talk about why this compound might actually be a powerful and supportive tool for mitochondrial health, brain function, and overall vitality.Some recent conversations have raised questions about Methylene Blue, so we're here to bring clarity and context. In this episode, we break down the research, talk through safety considerations, and explore why Methylene Blue might be one of the most underrated interventions out there.TOPICS DISCUSSED→ What are the benefits of Methylene Blue for the brain and cells?→ What does current research say about Methylene Blue?→ Who shouldn't use Methylene Blue, especially with SSRIs?→ How does Methylene Blue boost energy and clarity?→ Is Methylene Blue safe for brain and energy support?TIMESTAMPS→ 00:00:00 - Introduction → 00:01:55 - Is Methlyne Blue dangerous? → 00:05:54 - Methlyne Blue dosing → 00:08:03 - Troches & titration → 00:09:57 - Therapeutic benefits of Methylene Blue→ 00:15:05 - Cells with the most mitochondria → 00:18:40 - SSRIs and other Methylene Blue contraindications→ 00:23:39 - Supplement cycling→ 00:27:49 - SSRI's dopamine and Norepinephrine→ 00:34:30 - Methylene Blue & metabolism → 00:35:29 - Mitochondria dysfunction & stress → 00:38:21 - The dangers of blue light → 00:43:30 - The science of Methalyne blue → 00:47:41 - Daily Methalyne Blue usage → 00:51:43 - Red light and Methalyne Blue  → 00:53:12 - Methylene Blue, energy, & sleep → 00:55:07 - How to take Methylene Blue→ 00:59:13 - Resources for clinicians and practitioners SPONSORED BY:→ Troscriptions | There's a completely new way to optimize your health. Give it a try at troscriptions.com/SARAHK, or enter SARAHK at checkout for 10% off your first order.SHOW LINKS:→ The Ultimate Methylene Blue Episode - What Is It & Can It Give Me More Energy? Dr. Scott SherrCheck Out Dr Scott: → Troscriptions | There's a completely new way to optimize your health. Give it a try at troscriptions.com/SARAHK, or enter SARAHK at checkout for 10% off your first order.→ Podcast→ Instagram This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________My free product guide with all product recommendations and discount codes:https://s3.amazonaws.com/kajabi-storefronts-production/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdfCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! -https://www.sarahkleinerwellness.com/contact

Moms Across America founder Zen Honeycutt on the growing pesticide crisis—and how the MAHA movement plans to take action; Jefferey Jaxen details the MAHA Commission's 100-day report, the exploitation of autistic children within the medical system, and a must-see update on the WHO's looming Pandemic Treaty; Dr. Adam Urato shares alarming new findings on SSRI antidepressants and how prenatal exposure may be harming fetal brain development.Don't miss this critical episode.Guests: Zen Honeycutt, Adam Urato, M.D.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

Today, we're chatting with Dr. Adam Urato, a fetal and maternal medicine specialist, to discuss the lack of informed consent given to pregnant women concerning certain medications they're taking, namely SSRI antidepressants. Dr. Urato tells us about the crucial role serotonin plays in fetal development and the negative effects that SSRI use in pregnancy can have on an unborn baby. We also discuss the increase in medical interventions in pregnancy in recent decades and how these interventions may not be as positive as they seem. And is the pharmaceutical industry to blame for doctors' lack of concern over SSRI use? This episode is brought to you by Olive, the app built for the MAHA movement. Download the Olive app now to see what toxins are hiding in your groceries. Share the Arrows 2025 is on October 11 in Dallas, Texas! Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠sharethearrows.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for tickets now! Buy Allie's new book, "Toxic Empathy: How Progressives Exploit Christian Compassion": ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/4COtBxy⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Timecodes: (01:50) Dr. Urato introduction (04:12) Over-intervention in pregnancy (15:27) Medication safety in pregnancy (29:07) Lack of medical concern (34:50) SSRI effects on fetal development (46:32) Doctors avoiding catastrophe (51:48) Postpartum SSRI use (58:34) What is the FDA's role?  (01:00:58) Dr. Urato's criticism of Makena --- Today's Sponsors: Seven Weeks — Experience the best coffee while supporting the pro-life movement with Seven Weeks Coffee; use code ALLIE at ⁠⁠https://www.sevenweekscoffee.com⁠⁠ to save up to 25% off your first order, plus your free gift! Good Ranchers — Go to https://GoodRanchers.com and subscribe to any of their boxes (but preferably the Allie Beth Stuckey Box) to get free bacon, ground beef, seed oil free chicken nuggets, or wild-caught salmon in every box for life. Plus, you'll get $40 off when you use code ALLIE at checkout. Hillsdale College — Hillsdale College is offering more than 40 free online courses they offer on History, Economics, Politics, Philosophy, and more, including their new course, "Understanding Capitalism," all available for FREE. Go to https://hillsdale.edu/relatable to enroll. A Faith Under Siege — Watch the explosive new film "A Faith Under Siege: Russia's Hidden War on Ukraine Christians," detailing the persecution of believers under Russia's expanding occupation. Go to faithundersiege.com to watch today. --- Related Episodes: Ep 821 | Why Antidepressants Don't Fix Depression | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-821-why-antidepressants-dont-fix-depression-guest/id1359249098?i=1000616890403 Ep 822 | The Big Money Behind Big Medicine | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-822-the-big-money-behind-big-medicine-guest-dr/id1359249098?i=1000617050991 Ep 1031 | Psychiatry Is Killing People | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-1031-psychiatry-is-killing-people-guest-dr-roger/id1359249098?i=1000661830317 Ep 650 | COVID Comeback, Depression Meds, & Alzheimer's Scandal | Guest: Dr. Jay Bhattacharya https://podcasts.apple.com/us/podcast/ep-650-covid-comeback-depression-meds-alzheimers-scandal/id1359249098?i=1000571375454 Ep 983 | What Doctors Aren't Telling You About Antidepressants | Guest: Brooke Siem https://podcasts.apple.com/us/podcast/ep-983-what-doctors-arent-telling-you-about-antidepressants/id1359249098?i=1000652056518 --- Buy Allie's book, You're Not Enough (& That's Okay): Escaping the Toxic Culture of Self-Love: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://alliebethstuckey.com/book⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Relatable merchandise – use promo code 'ALLIE10' for a discount: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://shop.blazemedia.com/collections/allie-stuckey Learn more about your ad choices. Visit megaphone.fm/adchoices