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Continuum Audio
Parkinson Disease With Dr. Ashley Rawls

Continuum Audio

Play Episode Listen Later Aug 6, 2025 25:26


Parkinson disease is a neurodegenerative movement disorder that is increasing in prevalence as the population ages. The symptoms and rate of progression are clinically heterogenous, and medical management is focused on the individual needs of the patient. In this episode, Kait Nevel MD, speaks with Ashley Rawls, MD, MS, author of the article “Parkinson Disease” in the Continuum® August 2025 Movement Disorders issue. Dr. Nevel is a Continuum® Audio interviewer and a neurologist and neuro-oncologist at Indiana University School of Medicine in Indianapolis, Indiana. Dr. Rawls is an assistant professor at the University of Florida Health, Department of Neurology at the Norman Fixel Institute for Neurological Diseases in Gainesville, Florida Additional Resources Read the article:  Parkinson Disease Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @IUneurodocmom Guest: @DrRawlsMoveMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Nevel: Hello, this is Dr Kait Nevel. Today I'm interviewing Dr Ashley Rawls about her article on Parkinson disease, which appears in the August 2025 Continuum issue on movement disorders. Ashley, welcome to the podcast, and please introduce yourself to the audience. Dr Rawls: Thank you, Kait. Hello everyone, my name is Dr Ashley Rawls. I am a movement disorder specialist at the University of Florida Fixel Institute for Neurologic Diseases in Gainesville, Florida. It's a pleasure to be here. Dr Nevel: Awesome. To start us off talking about your article, can you share what you think is the most important takeaway for the practicing neurologist? Dr Rawls: Yes. I would say that my most important takeaway for this article is that Parkinson disease remains a clinical diagnosis. I think the field has really been advancing and trying to find a biomarker to help with diagnosis through ancillary testing. For example, with the dopamine transporter, the DAT scan, an alpha-synuclein skin biopsy, an alpha-synuclein amplification assay that can happen in blood and CSF. However, I think it's so critical to make sure that you have a very strong history and a very thorough physical exam and use those biomarkers or other testing to help with, kind of, bolstering your thoughts on what's going on with the patient. Dr Nevel: Great. And I can't wait to talk a little bit more about the ancillary testing and how you use that. Before we get to that, can you review with us some of the components of the clinical diagnosis of Parkinson disease? Dr Rawls: Yes. So, when I think about a person that comes in that might have a neurodegenerative disease, I think about two different features, mainly: both motor and Manon motor. So, for my motor features, I'm thinking about resting tremor, bradykinesia---which is fullness of movement with decrement over time---rigidity, and then a specific gait disturbance, a Parkinsonian gait, involving stooped posture, decreased arm swing. They can also have reemergent tremor while walking if they do have tremor as part of their disease process, and also in-block turning as they are walking down the hallway. So, those are my motor features that I look for. So now, when we're talking about a specific diagnosis of Parkinson disease, the one motor feature that you need to have is bradykinesia. The reason why I make sure to speak about bradykinesia, which is slowness of movement with decrement over time, is because people can still have Parkinson disease without having tremor, a resting tremor. So even though that's one of the core cardinal features that most of us will be able to notice very readily, you don't have to necessarily have a resting tremor to be diagnosed with Parkinson' disease. When I talk about nonmotor features, those are going to be the three, particularly the prodromal features that can occur even ten years before people have motor features, can be very prominent early on in the disease process. For example, hyposmia or anosmia for decrease or lack of sense of smell. Another one that we really look for is going to be RBD, or rapid eye movement behavior disorder; or REM behavior disorder, the person acting out their dreams, calling out, flailing their limbs, hitting their bed partner. And then the other one is going to be severe constipation. So those three prodromal nonmotor symptoms of hyposmia/anosmia, RBD or REM behavior disorder, and severe constipation can also make me concerned as a red flag that there is a sort of neurodegenerative issue like a Parkinson disease that may be going on with the patient. Dr Nevel: Great, thank you so much for that overview. While we're talking about the diagnosis, do you mind kind of going back to what you mentioned in the beginning and talking about the ancillary tests that sometimes are used to kind of help, again, bolster that diagnosis of Parkinson disease? You know, like the DAT or the alpha-synuclein skin biopsy. When should we be using those? Should we be getting these on everyone? And what scenarios should we really consider doing one of those tests? Dr Rawls: The scenario in which I would order one of the ancillary testing, particularly like a DAT scan or a skin biopsy, looking for alpha-synuclein is going to be when there are potential red flags or a little bit of confusion in regard to the history and physical that I need to have a little bit more clarification on. For example, if I have a patient that has a history of using dopamine blocking agents, for example, for severe depression; or they have a history of cancer diagnosis and they've been on a dopamine agent like metoclopramide; those I want to be mindful because if they're coming in to see me and they're having the symptoms of Parkinsonism---which is going to be resting tremor, bradykinesia rigidity, or gait disturbance---I need to try to figure out is it potentially due to a medication effect, particularly if they're still on the dopamine blockade medication, or is it something where they're actually having a neurodegenerative illness underneath it, like a Parkinson disease? The other situation that would make me order a DAT skin or a skin biopsy is going to be someone who is coming in that maybe has elements of essential tremor, they have more of a postural or an intention tremor that's very flapping and larger amplitude, and maybe have some mild symptoms and Parkinsonism that might be difficult to distinguish between other musculoskeletal things like arthritis, other imbalance issues from, you know, hip problems or knee problems and what have you. Then I might say, okay, let's see if there is some sort of neurodegeneration underneath this; that may be- that there could be, you know, potentially two elements like a central tremor and Parkinson disease going on. Or is this someone who actually really has Parkinson disease, but there's other factors that are kind of playing into that. Dr Nevel: Great, thank you for that. Gosh, things have really changed over the past fifteen years or so where we have this ancillary testing that we're able to use more, because what you read in the textbook isn't always what you see in clinic. And as you described, there are patients who… it's not as clear cut, and these tests can be helpful. Could you tell us more about the levodopa challenge test? How is this useful in clinical practice? And what are some key points that we should know about when utilizing this strategy for patients who we think have Parkinson disease? Dr Rawls: So, before we had all this ancillary testing with the DAT scan, the skin biopsy, the alpha-synuclein amplification assay, many times if you had a suspicion that a person that had Parkinson disease, but you weren't entirely sure, you would say, hey, listen, let us give you back the dopamine that your body may be missing and see if you have an improvement, in particular in your motor symptom. So, when I talk with my patients, I say, listen, I might have a strong suspicion that you have Parkinson disease. Doing a levodopa trial can not only be diagnostic, but also can be therapeutic as well. So, with this levodopa trial, what I end up doing is saying, okay, we're going to start the medication at a low dose because we are looking to see if you have improvement in three of the main cardinal motor symptoms. Obviously, tremor is much easier for us to see if it gets better. It's very obvious on exam, and the patients are more readily able to see it. Whereas stiffness and slowness is much harder to quantify and try to figure out. Am I stiff and slow because of potential muscle tightness from Parkinson disease, or is it something that's more of a musculoskeletal issue? So, I will tell persons, okay, we're looking for improvement in these three cardinal motor symptoms, and things that we're looking for is getting into and out of a car, into and out of a chair, turning over in bed, seeing how do we navigate ourselves in our daily lives? I give people the example of going through the grocery store, going through a busy airport. Are we able to move better and respond better to different changes in our environment which can give us a better clue of if our stiffness and slowness in particular are being improved with the medication? The other part of this is talking about potential side effects of the carbidopa- of the levodopa in particular. One big thing that I think limits people initially is going to be the nausea, vomiting, potential GI upset when starting this medication initially. So, oftentimes I will find people coming in, oh, you know, my outside doctor started me immediately on one tab of carbidopa/levodopa three times per day. I got nauseous, I threw up, and I never took the medication again. So often times I will start low and go slow because once someone throws up my medication, they are not going to want to take it again---with good reason. So, often times I will ask the patient, hey listen, are you very sensitive to medications? If you are very sensitive, we might start one tablet per day for a week, one tablet twice a day, and then go up until we get to two tablets three times a day if we're talking about carbidopa/levodopa. If someone is not as sensitive then I might go up a little bit quicker. What do we mean when we talk about 600 milligrams per day? So usually, the amount that I use is carbidopa/levodopa, 25/100; so, 100 milligrams being the levodopa portion. Many people just start off at 1 tab 3 times a day, which gives you 300 milligrams of levodopa, and they say, oh, it didn't work, I must not have Parkinson or something else. Well, it just may have been that we did not give an adequate trial and adequate dose to the person. Now if they're not able to tolerate the medication because of the side effects, that's something different. But if they don't have side effects and don't notice a difference, there is room to increase the carbidopa/levodopa or the levodopa replacement that you are using so that you can give it, you know, a very good try to see, is it actually improving resting tremor, bradykinesia and rigidity? Dr Nevel: Yeah, great. Thanks for that. When you diagnose a patient with Parkinson disease, how do you counsel that patient? How do you break that difficult news? And how do you counsel them on what to expect in the future and goals of treatment? I know that's a lot in that question, but it also is a lot that you do in one visit, oftentimes, or at least introduce these kind of concepts to patients in a single visit. Dr Rawls: One thing that I think is helpful for me is trying to understand where the patients and their families are when they come in. Because some of the patients come in and have no prior inkling that they may have a neurodegenerative illness like Parkinson disease. Some of my patients come in and say, I'm here for a second opinion for Parkinson disease. So, then I have an idea of where we are in regard to potential understanding of how to start the conversation going forward. If it is someone who is coming in and has not heard about Parkinson disease, or their family has not been made aware that that's the one reason why they're coming to see a movement disorder specialist, then I will start at the beginning After we finish our history, do a very thorough physical exam, I will talk about things that I heard in the history and that I see on the physical exam that make me concerned for a disease like Parkinson disease. I make sure to tell them where I'm getting my criteria from and not just start off, I think you have Parkinson, here's your medication. I think that's very jarring when you're talking with patients and their families, particularly if they had no idea that this could be a potential diagnosis on the table. Like I said, I will start off with recounting, this is what I've heard in your history that makes me concerned. This is what I've seen on your physical exam that makes me concerned. And I think you have Parkinson disease and here is why. And I'll tell them about the tenants like we discussed about Parkinson disease, both the motor and nonmotor symptoms that we see. So that's kind of the first part is, I make sure to lay it out and then open the room up for some questions and clarification. The other portion of this is that, when I'm talking about counseling the patient, I say, we do not expect Parkinson disease to decrease your lifespan. However, over time, our persons, because it is a neurodegenerative illnesses will accumulate deficits over time. So, more stiffness, more slowness, more walking problems. They may, if they have tremor, the tremor may become worse. If they don't have tremor, they might develop tremor in the future. If we're talking about the nonmotor symptoms that we talk about, the main ones are going to be issues with urinary problems, issues with bowels, and then the other thing is going to be neuropsychiatric issues like anxiety and depression. And those things become more prominent, usually, the nonmotor symptoms later on in the disease process, and then also cognitive impairment as well. I really want to make sure that they have the information that I'm seeing, and if there's anything that they want to correct on their end, as in they're saying, oh wait, well, actually I noticed something else, then that's usually when that comes out around kind of the wrapping-up portion of the visit. So, I think that's really important to, one, be very clear in what I am seeing and if there's red flags, and then tell them, okay this is not going to shorten your lifespan. However, over time, we do have other issues and problems that will arise and we can support you as best as we can through that. The one thing I also been very open with people about is- because our patients will say, is there anything I can do? What can be done? Is there any medication to slow down or stop things? And I let people know that unfortunately, right now there's not an intervention that slows down, stops, or reverses disease progression, with the exception of exercise. Consistent exercise has been found to help to slow down disease progression, okay? And also, it can help to release the dopamine already being made innately in the brain. And also, it can help with our cardiovascular health in the big thing: being balanced. Core strength, quadricep strength. So that's also something that people can work on that they should. And I let people know that exercise is as important as the medications themselves. Dr Nevel: Absolutely. And it's incredible how much they incorporate exercise into their daily lives and get active, people who weren't active before their diagnosis, and how much that can help. One question that I think patients sometimes ask is, when they understand how carbidopa/levodopa works and what the expectations are for that medication, that it's not a disease-modifying medication, but that it can help with their symptoms. And then they kind of hear, well as time goes on, they need higher doses or, you know, it doesn't control their motor symptoms as well. They'll say, okay well, is it better to wait then? Should I wait to start carbidopa/levodopa? Like in my mind, I'm only maybe going to get X amount of time from carbidopa/levodopa. So, I'd rather wait to start it than start it now. What do you say to them and how do you counsel them through that? Dr Rawls: So that is a common question that I do get with my patients. So, I tell people, I'm here for you. And it really depends on how you feel at this time. Because you have to weigh the risks and benefits of the medication itself. If someone who's very, very mild decides to take the medication, they feel nauseous, they're just going to say, hey, listen, it's not for me right now. I don't feel like I need it, and then stop, which is with definitely within their right. But what I always counsel patients as well is to say, the dopamine-producing neurons in the substantia nigra are starting to die over time. That is why we are getting the signs and symptoms of Parkinson disease. At some point, your brain is not going to produce enough dopamine that is needed for you to move when you want to move and not move when you don't want to move. Okay? Giving you at least the motor symptoms of Parkinson disease. With this, it's not that the medication stops working, it's just that you need more dopamine to help replace the dopamine that's being lost. However, the dopamine that you are taking or levodopa that you're taking orally is not going to be released as consistently as it is in your brain on demand and shut off when you don't need it. Hence the reason we get more motor fluctuations. Also, potential side effects in the medication like orthostatic hypertension, hallucinations, impulse control disorders. Because you're having to take more escalating doses, those side effects can become more prominent and also lead us to have to balance between the side effects and the medication itself. So, it's not that the medication does not work, your body needs more of it. Some people will say, oh, well, I want to wait, and I say, that's completely fine. However, my cutoff is basically saying, if you are finding that you, as the person who's afflicted is not able to get up in the morning like you want to, you're avoiding going to walk your dog or working in your garden, you know, because you feel stiff and feel slow; you're avoiding, you know, going out to the community, having lunch with your friends or your family because you're embarrassed by your tremor; this is something that is keeping you from living your life. And that's the time that we need to strongly consider starting the medications. So, a person afflicted will accumulate deficits. However, it's how much the deficits are going to affect you. So, if it's really affecting your life, we have tools and ways to help mitigate that. Dr Nevel: Yeah, absolutely. Are there any aspects of Parkinson disease management that you feel are maybe underrecognized or perhaps underutilized? In other words, you know, are there things that we the listeners should be maybe more aware of or think about offering or recommending to our patients that you think maybe aren't as much as they could be? Dr Rawls: I will say the nonmotor symptoms---in particular the neuropsychiatric symptoms with the anxiety and depression, usually later on disease process but also can be earlier as well---I think that is going to be something that is recognized but maybe undertreated in a lot of our patient population. I think part of that is also the fluctuations in dopamine that are occurring naturally in the person, but also, our patients, oftentimes with their medication regimen, really have to be on the ball taking the medication. If they're even 15 minutes late, 10 minutes late, 5 minutes late, we're now off, and now we're waiting for it to kick in. And so that can cause a lot of anxiousness even throughout the day. And then knowing that slowly over time that they're going to accumulate these motor and nonmotor deficits can definitely be problematic as well. There is obvious reason for this underlying potential anxiety and depression. And while we do talk about that and bring that up, sometimes patients will say, oh well, I don't think it's a problem right now. I don't have to mess with this. But usually at some point it does become an issue that usually the family members will bring up and saying, hey, you know, my loved one is very anxious. Or I've noticed that they're just really disengaged from what's going on in their lives and they are not talking as much, they're not going out as much. Again, that could be a combination of depression/anxiety, but it also can be a physical- a combination of, I'm not physically able to do these things, or, they're much more difficult for me to initiate doing these activities. I always want to be mindful. If my patients come in and they already have a diagnosis of depression or anxiety and they're already being treated by a mental health counselor, provider, or a psychiatrist, then I will work with providers so that we can try to optimize their medication regimen. The other thing is, well, if this is the first time that they're really being seen by someone and talking about their anxiety and depression, then oftentimes I will have them go back to their primary care and see if maybe an SSRI or SNRI will be helpful to try to help with the neuropsychiatric symptoms they may be experiencing. So that's one big one. Another one that I think that might be a little bit underappreciated is going to be drooling. Sometimes I'll come in and see my patients and notice some drooling that's happening with the mouth being open, not being able to initiate the swallowing reflex consistently throughout the day. Or they may be patting their face a lot with a napkin or a towel and then bringing that up and bringing it to light. Oh yeah. I have a lot of drooling while I'm awake. It's on my shirt. It's embarrassing. I feel like it's a little bit too much for me or my family. We have to put a bib on because I'm just drooling all throughout the day. That can really be uncomfortable and cause skin breakdown. It can also be socially embarrassing. So, there are some tools that I talk to people about with drooling. One thing I start with is going to be using sugar-free gum or candy while the person is awake to help initiate the swallow reflex, and sometimes that's all that's needed. There are other agents that can be used---like glycopyrrolate, sublingual atropine drops, and scopolamine patches---that can help with decreasing saliva production. But there can be side effects of making the entire body feel dry, and then also potential cardiac arrhythmias. If those are not helpful or they're contraindicated with the patient, another thing is going to be botulinum toxin injections. So those can be done on the parotid and salivary glands to decrease the amount of saliva that's being produced. So oftentimes people will come to me, because I'm also a botulinum toxin injector. I've been sent by some of my colleagues to inject our persons that have significant sialorrhea. Dr Nevel: Wonderful. Well, thank you so much for chatting with me today about your article. Again, today I've been interviewing Dr Ashley Rawls about her article on Parkinson disease, which appears in the August 2025 Continuum issue on movement disorders. Be sure to check out Continuum Audio episodes from this and other issues. And thank you to our listeners for joining today. And thank you, Ashley, for sharing all your knowledge with us today. Dr Rawls: Thank you, Kate, I appreciate your time. And have a great day, everyone. Dr Monteith: This is Dr Teshmae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Fempower Health
SSRIs in Pregnancy: What the FDA Panel Revealed About Mental Health, Medicine & Misinformation

Fempower Health

Play Episode Listen Later Aug 5, 2025 17:37


Episode SummaryIn this episode, Georgie Kovacs, founder of Fempower Health, unpacks the recent FDA hearing on SSRI use during pregnancy—an emotionally charged and complex conversation that brought together OB-GYNs, psychiatrists, pharmacologists, and advocates.Drawing on over 25 years in healthcare consulting and six years interviewing global women's health leaders, Georgie offers a balanced, deeply informed analysis of the real conversation that took place—beyond the headlines and controversy.This wasn't just a debate about antidepressants in pregnancy. It was a wider reckoning with how we define mental health, how we treat it, and the pressures facing clinicians and patients in a fragmented system. From risk-benefit tradeoffs and informed consent to how “depression” is diagnosed and operationalized, this episode explores what was said, what was missing, and what we need next.Whether you're a woman seeking clarity or a clinician striving to provide the best care, this episode breaks it all down.Discussion Points What actually happened at the FDA panel on SSRIs and pregnancy?Are SSRIs overprescribed—or unfairly stigmatized—during pregnancy?Is "depression" too broad of a diagnosis?How do mental health diagnoses affect treatment decisions for pregnant women?Why is informed consent inconsistent in SSRI prescribing?What are the long-term risks of untreated maternal depression?Are OB-GYNs expected to manage too much—including mental health?How does limited access to psychiatrists shape treatment options?What does better mental healthcare look like during pregnancy?Should we rethink how we integrate psychotherapy, medication, and lifestyle care?Expert Backgrounds MentionedOB-GYNs treating pregnant patients on SSRIsPsychiatrists both prescribing and deprescribing antidepressantsAcademic researchers investigating serotonin's effects on fetal developmentAdvocacy leaders spotlighting systemic barriers to mental health careResourcesFDA Hearing: https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-selective-serotonin-reuptake-inhibitors-ssris-and-pregnancy-07212025ACOG Response to FDA Hearing: https://www.acog.org/news/news-releases/2025/07/statement-on-benefit-of-access-to-ssris-during-pregnancySociety for Maternal-Fetal Medicine (SMFM) Statement https://www.smfm.org/news/smfm-statement-on-ssris-and-pregnancyRegulatory Focus Responds: https://www.raps.org/news-and-articles/news-articles/2025/7/fda-panel-debates-label-change-on-ssri-use-duringSTAT News Responds: https://www.statnews.com/2025/07/25/ssri-drugs-fda-review-panel-antidepressants-pregnancy/National Curriculum in Reproductive Psychiatry (NCRP) Responds: https://ncrptraining.org/press-release-ncrp-responds-to-fda-panel-on-ssri-use-in-pregnancy/

Mikkipedia
Mini Mikkipedia - Creatine for Your Brain? Exploring Cognitive and Mental Health Benefits

Mikkipedia

Play Episode Listen Later Aug 3, 2025 16:37


Mikki dives into the evolving science behind creatine—not just for muscles, but for brain health. Long known as a powerhouse for strength and performance, creatine is now gaining traction as a potential tool for cognitive enhancement and mental health support. Miki explores recent research shared by Dr. Nicholas Fabiano on creatine's potential role in improving outcomes in Alzheimer's, depression, and traumatic brain injury (TBI). She explains how higher doses may be required to impact brain creatine levels and discusses key findings around mood, cognition, and neurological recovery. Whether you're already taking creatine or considering it, this episode will broaden your understanding of how it could support not just your workouts, but your mental clarity and emotional well-being too.Highlights:Why creatine may support brain energy metabolism and cognitive functionEvidence for creatine's role in depression and SSRI-resistant casesHigh-dose creatine and its potential benefits in Alzheimer's and TBI recoveryDifferences in creatine needs between men and womenSafety considerations and dosing strategies for brain healthhttps://x.com/NTFabiano/status/1950155746034758119 Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Speaking of Writers
Edward L. Jones III-Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins,

Speaking of Writers

Play Episode Listen Later Jul 31, 2025 19:48


In 2005, Kim Crespi had what she later described as “the perfect life.” She and her husband, David—a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance—had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could bedestroyed in less than forty minutes. In January of 2006, while Kim was getting a haircut, Davidmurdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David had more questions than answers. In Medication, Mental Illness, and Murder, Edward L.Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries. Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mentalhealth systems, and of Big Pharma.EDWARD L. JONES III has been an award-winning writer in advertising and higher education. During his ad career, he won more than 350 awards for creativity. In his time away from advertising, Ed served as a community columnist for the Charlotte Observer. He lives in the Winston-Salem, North Carolina area. This is his first book.

Drew Berquist Live
SSRI's Strike Again: 4 Dead in New York City After Lone Gunman Storms Blackstone Building

Drew Berquist Live

Play Episode Listen Later Jul 29, 2025 56:45


SSRI's Strike Again: 4 Dead in New York City After Lone Gunman Storms Blackstone BuildingLive Show Monday-Thursday, 3pm est.SOCIALS: https://linktr.ee/drewberquistNEWS: https://DrewBerquist.comMERCH: https://RedBeachNation.com#DrewBerquist #ThisIsMyShow #TIMSTop 100 Political News Podcast with https://www.millionpodcasts.com/political-news-podcasts/#1 Counterterrorism Podcast on Feedspot: https://podcast.feedspot.com/counter_terrorism_podcasts/Show Notes/Links:Trump signs EO to curb NIL and money in college sportshttps://x.com/premefootball/status/1948479059153092936NY Post headline day after shootinghttps://x.com/nypost/status/1950139161744117811Media described the shooter as white, or light skinnedhttps://x.com/autismcapital/status/1949991013138977120?s=46&t=uaL12_jzouHgBP9nzey-rghttps://x.com/ericldaugh/status/1949990259191697897?s=46&t=uaL12_jzouHgBP9nzey-rgNYC shooting timelinehttps://x.com/nicksortor/status/1950028665867137211Dems call for gun ban after NYC shootinghttps://x.com/westernlensman/status/1950022078091944324?s=46&t=uaL12_jzouHgBP9nzey-rgCincinnati Police Chief whines about social media in press conferencehttps://x.com/Babygravy9/status/19501250987923090815 charged in horrifying viral Cincinnati brawl that left woman knocked out cold https://x.com/Lukewearechange/status/1949949568067461446Pete Buttigieg: Trump is appointing "incompetent people" to serve in the governmenthttps://x.com/WesternLensman/status/1949935354011930830See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Regular Joe Show
RJS - 7/29/25 - Segment 1

The Regular Joe Show

Play Episode Listen Later Jul 29, 2025 15:47


Tragedy in NYC. RFK Jr is looking into SSRI medications. See omnystudio.com/listener for privacy information.

The Regular Joe Show
RJS - 7/29/25 - Whole Show

The Regular Joe Show

Play Episode Listen Later Jul 29, 2025 110:50


A tragic shooting in NYC. RFK Jr. is investigating the use and safety of SSRI use for mental illnesses. The tragic assault of a couple in Cincinnati. Bill Maher flips his opinion on the tariffs. Does Eric Swalwell know what his job duties are? Should the legal driving age change? What about the legal drinking age? VP Vance talks BBB. Chuck Schumer is not a fan of the trade deal with the EU. See omnystudio.com/listener for privacy information.

The Highwire with Del Bigtree
Episode 434: TRIUMPH OVER TRAGEDY

The Highwire with Del Bigtree

Play Episode Listen Later Jul 25, 2025 127:27


Jefferey Jaxen returns with breaking coverage of a major shift at the FDA: for the first time, the agency is holding a public panel to investigate the dangers of SSRI drugs during pregnancy. Could this lead to a long-overdue black box warning?Meanwhile, FDA Commissioner Dr. Marty Makary makes a stunning admission—he personally knows people who have been injured or killed by the COVID-19 vaccine. As the U.S. barrels toward net zero policies and rapid AI expansion, America's energy grid faces unprecedented strain.Plus, don't miss our powerful and emotional interview with the Hammond family, who share their heartbreaking story of losing their daughter Malaya in the devastating Texas flood. Her final act of heroism saved her family. Their journey through grief, faith, and resilience will move and inspire you.Guests: Matthew & Liz HammondBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

The Third Wave
Dave Rabin M.D., Ph.D. - Microdosing on SSRIs? A Psychiatrist's Take

The Third Wave

Play Episode Listen Later Jul 25, 2025 54:34


Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety. Find full show notes and links here: https://thethirdwave.co/podcast/episode-313b/?ref=278 Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work. If you're a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights. Highlights: How SSRIs blunt emotional range and alter awareness The neuroscience of serotonin and psychedelic receptors Serious risks of serotonin syndrome when mixing with SSRIs Ketamine's role in tapering and unlocking neuroplasticity Practical tools to regulate the nervous system during SSRI withdrawal Recommended psilocybin strains for sensitive or anxious clients How long-term SSRI use may (or may not) affect psychedelic response Safety-first protocols for psychedelic integration The future of microdosing as a sustainable antidepressant approach Episode Links: Dr. Dave Rabin's Website Dr. Dave on Instagram Dr. Dave on LinkedIn Apollo Neuro Last week's bonus episode with Dr. Robin Carhart-Harris: SSRIs vs. Psychedelics: From Blunting to Rebooting  Episode 218 with Dr. Dave Rabin Episode 74 with Dr. Dave Rabin Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute's Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More. Episode Sponsor: Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout

Women's Wellness Psychiatry
Reflections on the FDA Panel of SSRIs in Pregnancy

Women's Wellness Psychiatry

Play Episode Listen Later Jul 24, 2025 13:18


The FDA recently held a panel on the safety of SSRI medications in pregnancy, which was uninformed and negatively impacts perinatal patients and their mental health. This episode discusses that scientifically inaccurate event. Resources:ACOG Statement on the FDA Panel: https://www.acog.org/news/news-releases/2025/07/statement-on-benefit-of-access-to-ssris-during-pregnancy To learn more about me and my reproductive & integrative psychiatry clinic helping patients across California, please visit - AnnaGlezerMD.comTo sign up for the Fellowship in Reproductive & Integrative Psychiatry, please visit:  PsychiatryFellowship.com. 

Revelations Podcast
Breaking Addiction and Spiritual Darkness through Divine Encounter with Jesus (Ft. Tommy Doyle)

Revelations Podcast

Play Episode Listen Later Jul 23, 2025 71:57


A life marked by pain, addiction, and spiritual warfare can feel like a dead end. Substance abuse, anxiety, and demonic oppression often isolate people in cycles of shame and confusion. Many find themselves desperate for freedom, yet unsure how to break the chains that hold them back. The battle is not only physical and emotional, it's spiritual. And it often takes something greater than willpower to escape it: a divine encounter.In this episode of Revelations Podcast, host Reagan Kramer sits down with Tommy Doyle. He is the International Director of Uncharted Ministries and son of renowned missionary leaders Tom and Joanne Doyle. Tommy takes us on a riveting journey from being a pastor's kid entangled in alcoholism, panic attacks, and spiritual torment, to becoming a frontline missionary reaching war zones in the Middle East with the love of Christ. His battles with demonic forces and deliverance through a divine encounter of Jesus offer a powerful message of hope for anyone navigating the wilderness of addiction or doubt.Be equipped with spiritual tools to confront addiction, anxiety, and spiritual warfare with the authority of Jesus. This episode is for hurting hearts, wandering believers, and anyone ready to trade despair for lasting freedom in Christ.Here are three reasons why you should listen to this episode:Discover the spiritual component of addiction and how it can be broken through a divine encounter with Jesus.Explore the reality of spiritual warfare in regions like Egypt and how prayer activates victory over darkness.Learn how Tommy's story shows hope for those battling both anxiety and faith deconstruction.Become Part of Our Mission! Support The Revelations Podcast:Your support fuels our mission to share transformative messages of hope and faith. Click here to learn how you can contribute and be part of this growing community!ResourcesMore from the Revelations Podcast hosted by Reagan Kramer: Website | Instagram | Apple Podcast | YoutubeUncharted Ministries: WebsiteUncharted Adventures: Website“Dreams and Visions: Is Jesus Awakening the Muslim World?” by Tom Doyle“Women Who Risk” by Tom and Joanne Doyle“Spiritual Warfare: Christians, Demonization, and Deliverance” by Dr. Karl Payne Bible Verses2 Timothy 1:7This Episode is brought to you by Advanced Medicine AlternativesGet back to the active life you love through natural & regenerative musculoskeletal healing: https://www.georgekramermd.com/Episode Highlights[00:36] Freedom from Addiction and the Fight for the SoulAddiction, anxiety, and spiritual warfare can make people feel trapped and unseen.Many silently battle overwhelming darkness, believing healing is out of reach.Tommy Doyle, International Director of Uncharted Ministries, knows this struggle firsthand.[03:21] Tommy: “We have so many good friends and so many ministry partners over there, that that's just really where our heart was, and we were part of another ministry before that that we loved dearly, so many great people and everything.”Once bound by addiction and anxiety, Tommy now leads missions that bring healing and hope across the Middle East.[05:26] Ministry Work in the Middle EastTommy describes Uncharted Ministries' work across war-torn regions of the Middle East.He recalls visiting the Gaza Strip a month after a major attack, wearing flak jackets and traveling with armed EMTs.Despite the chaos, they shared comfort and reminded hurting communities that they are not forgotten.Through every mission, Tommy emphasizes the power of showing up and bringing the love of Christ.[12:19] Personal Testimony and Early LifeTommy grew up in a large Christian family, deeply involved in church life as a pastor's kid.Despite strong early faith, he experienced rejection and betrayal from peers in church leadership.That emotional wound led him to pull away and seek belonging in sports and party culture.This shift laid the groundwork for his eventual descent into substance use and spiritual drift.[24:23] Struggles with Addiction and Turning PointTommy began justifying casual partying, which escalated into drug dealing and daily alcohol use.A raid by federal agents became a wake-up call, but the pull of addiction remained strong.Panic attacks worsened his condition, and alcohol became his go-to form of self-medication.Despite several attempts to quit, nothing brought lasting freedom—until he cried out to God.[26:42] Egypt Mission Trip and Spiritual AwakeningTommy joined a mission trip to Egypt to support his mother's outreach to Muslim women.While caring for children there, he was struck by a deep conviction to return to a life of purpose.That moment reignited his faith, shifted his focus, and set him on a path of full sobriety.He returned home and committed to healing through a Christ-centered Celebrate Recovery program.[36:11] Supernatural Encounter in EgyptDuring a foot-washing ceremony, Tommy witnessed a woman visibly possessed and delivered through the name of Jesus.[39:47] Tommy: “Every time that something dark and scary would happen, witnessed by other people too, the power of the name of Jesus was enough to eradicate it and, and that's just so life-giving.”Later that night, he and his brother encountered a terrifying demonic presence outside their desert compound.Prayer in Jesus' name broke the oppression, revealing that when the demonic and divine encounter each other, the authority of Christ prevails over darkness.These spiritual battles confirmed the reality of unseen warfare—and the power believers carry.[47:49] Territorial Spirits and the Battle Over RegionsTommy and Reagan reflect on how demonic strongholds operate not just personally, but over entire regions.In spiritually charged areas like the Middle East, the Enemy fiercely resists gospel work.Tommy shares how even Bible translation efforts in unreached areas face constant spiritual interference.Yet through it all, God's power continues to break ground where darkness has long ruled.[52:45] The Link Between Medication and AddictionTommy discusses the role anti-anxiety medication played in intensifying his alcohol cravings.He noticed his dependence on alcohol spiked after starting an SSRI prescribed for panic attacks.This connection led him to research and ultimately discontinue the medication after his spiritual breakthrough.He encourages others to evaluate their health journeys prayerfully and seek Spirit-led guidance.[58:39] Advice for Overcoming Addiction and AnxietyTommy urges listeners to admit powerlessness and seek a divine encounter with Jesus as the first step to healing.By trusting Him, we take a faithful path to healing.He shares practical advice for managing anxiety, including diet, outdoor activity, and community support.Accountability and honesty are key—especially with trusted friends and family.Above all, he emphasizes that true freedom from addiction and fear comes through Christ alone.[1:03:43] Tommy: “I did not need a foreign substance to be happy and enjoy life. And that's such a lie if, if that's holding you back, reconnect with the Lord.”[1:05:52] Living Free From Darkness to Purpose in ChristTommy reminds listeners that surrender is not weakness but the beginning of real strength.He shares how 2 Timothy 1:7 has anchored him through fear and addiction.God's healing is available to anyone ready to leave darkness and walk into His light.Learn more about Tommy's work through Uncharted Ministries and Uncharted Adventures at unchartedministries.com.About Tommy DoyleTommy Doyle is a missionary leader, speaker, and redeemed overcomer called to bring light into the darkest places. As the International Director of Uncharted Ministries, he continues the legacy of his parents, Tom and Joanne Doyle, by leading gospel-centered outreach in the Middle East and beyond. From war zones to remote villages, Tommy helps bring humanitarian aid, spiritual support, and the message of Jesus to those living in fear, trauma, or persecution. His work bridges cultures and faiths, demonstrating the power of God's love across some of the most spiritually resistant regions in the world.Once bound by addiction, anxiety, and demonic oppression, Tommy experienced radical deliverance during a divine encounter. On his mission trip to Egypt, he reignited his faith and reshaped his purpose. Now over a decade sober, he uses his testimony to reach those walking through their own wilderness. With firsthand experience in spiritual warfare and recovery, Tommy equips others to confront addiction, overcome fear, and live with bold, Christ-centered purpose. His story is a powerful reminder that no one is too far gone for the grace of God.Connect with Tommy through the Uncharted Ministries website.Enjoyed this Episode?If you did, subscribe and share it with your friends!Post a review and share it! If you enjoyed tuning in about generational curses and how to break them, leave us a review. You can also share this with your friends and family. Freedom from addiction, anxiety, and spiritual oppression begins with surrender. When you experience a divine encounter with Jesus, darkness loses its grip. Let this be a reminder that no matter how far you've gone, healing and purpose are still possible.Have any questions? You can connect with me on Instagram.Thank you for tuning in! For more updates, tune in on Apple Podcasts

Back to The Basics
68: Feeling Off in Your 30s, 40s or 50s? – The Best Time to Start Hormone Therapy with Dr. Terri DeNeui

Back to The Basics

Play Episode Listen Later Jul 20, 2025 59:27


>>Want more information like this? Sign up for Modern Endocrine's⁠⁠⁠⁠⁠⁠⁠⁠ ⁠newsletter: https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠

The Third Wave
Robin Carhart-Harris, Ph.D. - SSRIs vs. Psychedelics: From Blunting to Rebooting

The Third Wave

Play Episode Listen Later Jul 18, 2025 58:43


In this episode of The Psychedelic Podcast, Paul F. Austin is joined by renowned neuroscientist Dr. Robin Carhart-Harris and microdosing policy advocate John Downs for a replay of a live event originally held on June 10th, Microdosing vs. SSRIs: What's Happening in the Brain and Why It Matters. Find full show notes and links here: https://thethirdwave.co/podcast/episode-312b/?ref=278 Together, they explore the scientific distinctions between SSRIs and psychedelics, focusing on neuroimaging, brain entropy, emotional processing, and the REBUS model. Dr. Carhart-Harris shares key insights from landmark studies on psilocybin therapy and discusses the evidence (and limitations) around microdosing. John Downs closes the conversation with an update on the Microdosing Collective's efforts to shift policy and expand access. Robin Carhart-Harris, PhD is a neuropharmacologist, psychologist, and Ralph Metzner Distinguished Professor in Neurology and Psychiatry at the University of California, San Francisco. He leads the Psychedelics Division at UCSF's Neuroscape and formerly founded and led the Centre for Psychedelic Research at Imperial College London. John Downs is Executive Director of the Microdosing Collective, advocating for responsible policy reform and legal access to microdosing. With 25 years' experience in sales, business development, and emerging markets, John helps individuals optimize mindset, performance, and purpose. Episode Highlights: Why SSRIs blunt, while psychedelics reset emotional processing How psilocybin compares to antidepressants in clinical trials Brain entropy, plasticity, and the REBUS model explained The role of the default mode network in mental health Why microdosing research is still so limited Ketamine vs. psilocybin: differences in brain mechanisms Is serotonin syndrome a real microdosing risk? Can psychedelics reverse long-term SSRI effects? The Microdosing Collective's mission for policy reform What Robin Carhart-Harris' upcoming book will explore Episode Links: Robin's lab & upcoming book Microdosing Collective Join Dr. Robin Carhart-Harris at our Practitioner Intensive (November 5–10, Costa Rica) Episode Sponsors: Golden Rule Mushrooms - Get a lifetime discount of 10% with code THIRDWAVE at checkout Psychedelic Coacing Isntitute's  Intensive for Psychedelic Professionals in Costa Rica - a transformative retreat for personal and professional growth.

Rio Bravo qWeek
Episode 198: Fatigue

Rio Bravo qWeek

Play Episode Listen Later Jul 18, 2025 31:17


Episode 198: Fatigue.  Future doctors Redden and Ibrahim discuss with Dr. Arreaza the different causes of fatigue, including physical and mental illnesses. Dr. Arreaza describes the steps to evaluate fatigue. Some common misconceptions are explained, such as vitamin D deficiency and “chronic Lyme disease”. Written by Michael Ibrahim, MSIV, and Jordan Redden, MSIV, Ross University School of Medicine. Edits and comments by Hector Arreaza, MDYou are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Dr. Arreaza: Today is a great day to talk about fatigue. It is one of the most common and most complex complaints we see in primary care. It involves physical, mental, and emotional health. So today, we're walking through a case, breaking down causes, red flags, and how to work it up without ordering the entire lab catalog.Michael:Case: This is a 34-year-old female who comes in saying, "I've been feeling drained for the past 3 months." She says she's been sleeping 8 hours a night but still wakes up tired. No recent illnesses, no weight loss, fever, or night sweats. She denies depression or anxiety but does report a lot of work stress and taking care of her two little ones at home. She drinks 2 cups of coffee a day, doesn't drink alcohol, and doesn't use drugs. No medications, just a multivitamin. Regular menstrual cycles—but she's noticed they've been heavier recently.Jordan:Fatigue is a persistent sense of exhaustion that isn't relieved by rest. It's different from sleepiness or muscle weakness.Classification based on timeline:    •   Acute fatigue: less than 1 month    •   Subacute: 1 to 6 months    •   Chronic: more than 6 monthsThis patient's case is subacute—going on 3 months now.Dr. Arreaza:And we can think about fatigue in types:    •   Physical fatigue: like muscle tiredness after activity    •   Mental fatigue: trouble concentrating or thinking clearly (physical + mental when you are a medical student or resident)    •    Pathological fatigue: which isn't proportional to effort and doesn't get better with restAnd of course, there's chronic fatigue syndrome, also called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), which is a diagnosis of exclusion after 6 months of disabling fatigue with other symptoms.Michael:The differential is massive. So, we can also group it by systems.Jordan:Let's run through the big ones.Endocrine / Metabolic Causes    • Hypothyroidism: A classic cause of fatigue. Often associated with cold intolerance, weight gain, dry skin, and constipation. May be subtle and underdiagnosed, especially in women.    • Diabetes Mellitus: Both hyperglycemia and hypoglycemia can cause fatigue. Look for polyuria, polydipsia, weight loss, or blurry vision in undiagnosed diabetes.    • Adrenal Insufficiency: Think of this when fatigue is paired with hypotension, weight loss, salt craving, or hyperpigmentation. Can be primary (Addison's) or secondary (e.g., due to long-term steroid use).Michael: Hematologic Causes    • Anemia (especially iron deficiency): Very common, especially in menstruating women. Look for fatigue with pallor, shortness of breath on exertion, and sometimes pica (craving non-food items).     • Vitamin B12 or Folate Deficiency: B12 deficiency may present with fatigue plus neurologic symptoms like numbness, tingling, or gait issues. Folate deficiency tends to present with megaloblastic anemia and fatigue.    • Anemia of Chronic Disease: Seen in patients with chronic inflammatory conditions like RA, infections, or CKD. Typically mild, normocytic, and improves when the underlying disease is treated.Michael: Psychiatric Causes    • Depression: A major driver of fatigue, often underreported. May include anhedonia, sleep disturbance, appetite changes, or guilt. Sometimes presents with only somatic complaints.    • Anxiety Disorders: Mental fatigue, poor sleep quality, and hypervigilance can leave patients feeling constantly drained.    • Burnout Syndrome: Especially common in caregivers, healthcare workers, and educators. Emotional exhaustion, depersonalization, and reduced personal accomplishment are key features.Jordan: Infectious Causes    • Epstein-Barr Virus (EBV):Mononucleosis is a well-known cause of fatigue, sometimes lasting weeks. May also have sore throat, lymphadenopathy, and splenomegaly.    • HIV:Consider it in high-risk individuals. Fatigue can be an early sign, along with weight loss, recurrent infections, or night sweats.    • Hepatitis (B or C):Can present with chronic fatigue, especially if liver enzymes are elevated. Screen at-risk individuals.    • Post-viral Syndromes / Long COVID:Fatigue that lingers for weeks or months after viral infection. Often, it includes brain fog, muscle aches, and post-exertional malaise.Important: Chronic Lyme disease is a controversial term without a consistent clinical definition and is often used to describe patients with persistent, nonspecific symptoms not supported by objective evidence of Lyme infection. Leading medical organizations reject the term and instead recognize "post-treatment Lyme disease syndrome" (PTLDS) for persistent symptoms following confirmed, treated Lyme disease, emphasizing that prolonged antibiotic therapy is not effective. Research shows no benefit—and potential harm—from extended antibiotic use, and patients with unexplained chronic symptoms should be thoroughly evaluated for other possible diagnoses.Michael: Cardiopulmonary Causes    •   Congestive Heart Failure (CHF): Fatigue from poor perfusion and low cardiac output. Often comes with dyspnea on exertion, edema, and orthopnea.    •   Chronic Obstructive Pulmonary Disease (COPD): Look for a smoking history, chronic cough, and fatigue from hypoxia or the work of breathing.    •   Obstructive Sleep Apnea (OSA): Daytime fatigue despite adequate hours of sleep. Patients may snore, gasp, or report morning headaches. High suspicion in obese or hypertensive patients.Jordan:Autoimmune / Inflammatory Causes    •   Systemic Lupus Erythematosus (SLE): Fatigue is often an early symptom. May also see rash, arthritis, photosensitivity, or renal involvement.    •   Rheumatoid Arthritis (RA): Fatigue from systemic inflammation. Morning stiffness, joint pain, and elevated inflammatory markers point to RA.    •   Fibromyalgia: A chronic pain syndrome with widespread tenderness, fatigue, nonrestorative sleep, and sometimes cognitive complaints ("fibro fog").Cancer / Malignancy    •   Leukemia, lymphoma, or solid tumors: Fatigue can be the first symptom, often accompanied by weight loss, night sweats, or unexplained fevers. Consider when no other cause is evident.Michael:Medications:Common culprits include:    ◦   Beta-blockers: Can slow heart rate too much.    ◦   Antihistamines: Sedating H1 blockers like diphenhydramine.    ◦   Sedatives or sleep aids: Can cause grogginess and daytime sedation.    •   Substance Withdrawal: Fatigue can be seen in withdrawal from alcohol, opioids, or stimulants. Caffeine withdrawal, though mild, can also contribute.Dr. Arreaza:Whenever we evaluate fatigue, we need to keep an eye out for red flags. These should raise suspicion for something more serious:    •   Unintentional weight loss    •   Night sweats    •   Persistent fever    •   Neurologic symptoms    •   Lymphadenopathy    •   Jaundice    •   Palpitations or chest painThis patient doesn't have these—but that doesn't mean we stop here.Dr. Arreaza:Those are a lot of causes, we can evaluate fatigue following 7 steps:Characterize the fatigue.Look for organic illness.Evaluate medications and substances.Perform psychiatric screening.Ask questions about quantity and quality of sleep.Physical examination.Undertake investigations.So, students, do we send the whole lab panel?Michael:Not necessarily. Labs should be guided by history and physical. But here's a good initial panel:    •   CBC: To check for anemia or infection    • TSH: Screen for hypothyroidism    • CMP: Look at electrolytes, kidney, and liver function    • Ferritin and iron studies    • B12, folate    • ESR/CRP for inflammation (not specific)    • HbA1c if diabetes is on the radarJordan:And if needed, consider:    • HIV, EBV, hepatitis panel    • ANA, RF    • Cortisol or ACTH stimulation testImaging? Now that's rare—unless there are specific signs. Like chest X-ray for possible cancer or TB, or sleep study if you suspect OSA.Dr. Arreaza:Unaddressed fatigue isn't just inconvenient. It can impact on quality of life, affect job performance, lead to mood disorders, delay diagnosis of serious illness, increase risk of accidents—especially driving. So, don't ignore your patients with fatigue!Jordan:And some people—like women, caregivers, or shift workers—are especially at risk.Michael:The cornerstone of treatment is addressing the underlying cause.Jordan:If it's iron-deficiency anemia—treat it. If it's depression—get mental health involved. But there's also: Lifestyle Support: Better sleep hygiene, light physical activity, mindfulness or CBT for stress, balanced nutrition—especially iron and protein, limit caffeine and alcoholDr. Arreaza:Sometimes medications help—but rarely. And for chronic fatigue syndrome, the current best strategies are graded exercise therapy and CBT, along with managing specific symptoms. Beta-alanine has potential to modestly improve muscular endurance and reduce fatigue in older adults, but more high-quality research is needed.SSRI: fluoxetine and sertraline. Iron supplements: Even without anemia, but low ferritin [Anecdote about low ferritin patient]Jordan:This case reminds us to take fatigue seriously. In her case, it may be multifactorial—work stress, caregiving burden, and possibly iron-deficiency anemia. So, how would we wrap up this conversation, Michael?Michael:We don't need to order everything under the sun. A focused history and exam, targeted labs, and being alert to red flags can guide us.Jordan:And don't forget the basics—sleep, stress, and nutrition. These are just as powerful as any prescription.Dr. Arreaza:We hope today's episode on fatigue has given you a clear framework and some practical tips. If you enjoyed this episode, share it and subscribe for more evidence-based medicine!Jordan:Take care—and get some rest~___________________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:DynaMed. (2023). Fatigue in adults. EBSCO Information Services. https://www.dynamed.com (Access requires subscription)Jason, L. A., Sunnquist, M., Brown, A., Newton, J. L., Strand, E. B., & Vernon, S. D. (2015). Chronic fatigue syndrome versus systemic exertion intolerance disease. Fatigue: Biomedicine, Health & Behavior, 3(3), 127–141. https://doi.org/10.1080/21641846.2015.1051291Kroenke, K., & Mangelsdorff, A. D. (1989). Common symptoms in ambulatory care: Incidence, evaluation, therapy, and outcome. The American Journal of Medicine, 86(3), 262–266. https://doi.org/10.1016/0002-9343(89)90293-3National Institute for Health and Care Excellence. (2021). Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: Diagnosis and management (NICE Guideline No. NG206). https://www.nice.org.uk/guidance/ng206UpToDate. (n.d.). Approach to the adult patient with fatigue. Wolters Kluwer. https://www.uptodate.com (Access requires subscription)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Kill Them with Comedy - Comedians, crime & conspiracies
170. Nonce Wars ep1: The Phantom MAN-ace of France | Squishy Logic

Kill Them with Comedy - Comedians, crime & conspiracies

Play Episode Listen Later Jul 18, 2025 124:00


Its Friday Highday, my male hormones are raging, you know what that means...i could be the French first lady...& if you have a penis then you could too! (allegedly, no one needs to get sued here.The first of an ongoing series crossing both Squishy Logic and 2 Peas in a PodcastComedians Kd Hinken and Nathan Parish take a look at the Brigitte Macron scandal...was she born a man? is she her brother? why does nobody seem to care that either way shes a nonce? France be Francing? We'll ask these questions and more in todays live Squishy Logic...you're welcome.They also look at the ongoing Epstein saga, Trumps reaction, jimmy Saville is in the new 28 years later episode and moreTimecodes 7mins Epstein 20mins Water is running out 25mins The dangers of SSRI tablets & why Kd has stopped taking all his medications (spoiler, NHS don't know what they are doing)28mins Epstein cont.30min Brigitte Macron scandal, Trans & Emmanuel Paedophile grooming full background34mins Candace Owens involvement 38. mins Nonce Wars 1hr.26 Jimmy Saville is in 28 Years later 1.44.00 Can Kd lucid dream?1.49.00 Nathan has sleep paralysis

Authentically ADHD
ADHD and Co-Occurring Conditions: Anxiety, Mood, and Learning Disorders

Authentically ADHD

Play Episode Listen Later Jul 12, 2025 81:23


Welcome or welcome back to Authentically ADHD, the podcast where we embrace the chaos and magic of the ADHD brain. Im carmen and today we're diving into a topic that's as complex as my filing system (which is to say, very): ADHD and its common co-occurring mood and learning disorders. Fasten your seatbelts (and if you're like me, try not to get distracted by the shiny window view) – we're talking anxiety, depression, OCD, dyslexia, dyscalculia, and bipolar disorder, all hanging out with ADHD.Why cover this? Because ADHD rarely rides solo. In fact, research compiled by Dr. Russell Barkley finds that over 80% of children and adults with ADHD have at least one other psychiatric disorder, and more than half have two or more coexisting conditions. Two-thirds of folks with ADHD have at least one coexisting condition, and often the classic ADHD symptoms (you know, fidgeting, daydreaming, “Did I leave the stove on?” moments) can overshadow those other disorders. It's like ADHD is the friend who talks so loud at the party that you don't notice the quieter buddies (like anxiety or dyslexia) tagging along in the background.But we're going to notice them today. With a blend of humor, sass, and solid neuroscience (yes, we can be funny and scientific – ask me how I know!), we'll explore how each of these conditions shows up alongside ADHD. We'll talk about how they can be misdiagnosed or missed entirely, and—most importantly—we'll dish out strategies to tell them apart and tackle both. Knowledge is power and self-awareness is the key, especially when it comes to untangling ADHD's web of quirks and comrades in chaos. So, let's get into it!ADHD and Anxiety: Double Trouble in OverdriveLet's start with anxiety, ADHD's frequent (and frantic) companion. Ever had your brain ping-pong between “I can't focus on this work” and “I'm so worried I'll mess it up”? That's ADHD and anxiety playing tango in your head. It's a double whammy: ADHD makes it hard to concentrate, and anxiety cranks up the worry about consequences. As one study notes, about 2 in 5 children with ADHD have significant problems with anxiety, and over half of adults with ADHD do as well. In other words, if you have ADHD and feel like a nervous wreck half the time, you're not alone – you're in very good (and jittery) company.ADHD and anxiety can look a lot alike on the surface. Both can make you restless, unfocused, and irritable. I mean, is it ADHD distractibility or am I just too busy worrying about everything to pay attention? (Hint: it can be both.) Especially for women, ADHD is often overlooked and mislabeled as anxiety. Picture a girl who can't concentrate in class: if she's constantly daydreaming and fidgety, one teacher calls it ADHD. Another sees a quiet, overwhelmed student and calls it anxiety. Same behavior, different labels. Women in particular have had their ADHD misdiagnosed as anxiety or mood issues for years, partly because anxious females tend to internalize symptoms (less hyperactive, more “worrier”), and that masks the ADHD beneath.So how do we tell ADHD and anxiety apart? One clue is where the distraction comes from. ADHD is like having 100 TV channels in your brain and someone else is holding the remote – your attention just flips on its own. Anxiety, on the other hand, is like one channel stuck on a horror movie; you can't focus on other things because a worry (or ten) is running on repeat. An adult with ADHD might forget a work deadline because, well, ADHD. An adult with anxiety might miss the deadline because they were paralyzed worrying about being perfect. Both end up missing the deadline (relatable – ask me how I know), but for different reasons.Neuroscience is starting to unravel this knot. There's evidence of a genetic link between ADHD and anxiety – the two often run in the family together. In brain studies, both conditions involve irregularities in the prefrontal cortex (the brain's command center for focus and planning) and the limbic system (emotion center). Essentially, if your brain were a car, ADHD means the brakes (inhibition) are a bit loose, and anxiety means the alarm system is hyper-sensitive. Combine loose brakes with a blaring alarm and you get… well, us. Fun times, right?Here's an interesting tidbit: Females with ADHD are more likely to report anxiety than males. Some experts think this is partly due to underdiagnosed ADHD – many girls grew up being told they were just “worrywarts” when in fact ADHD was lurking underneath, making everyday life more overwhelming and thus feeding anxiety. As Dr. Thomas Brown (a top ADHD expert) points out, emotional regulation difficulties (like chronic stress or worry) are characteristic of ADHD, even though they're not in the official DSM checklist. Our ADHD brains can amplify emotions – so a normal worry for someone else becomes a five-alarm fire for us.Now, action time: How do we manage this dynamic duo? The first step is getting the right diagnosis. A clinician should untangle whether symptoms like trouble concentrating are from anxiety, ADHD, or both. They might ask: Have you always had concentration issues (pointing to ADHD), or did they start when your anxiety kicked into high gear? Also, consider context – ADHD symptoms occur in most settings (school, work, home), while pure anxiety might spike in specific situations (say, social anxiety in crowds, or panic attacks only under stress).Treatment has to tackle both. Therapy – especially Cognitive Behavioral Therapy (CBT) – is a rockstar here. CBT can teach you skills to manage worry (hello, deep breathing and logical rebuttals to “what if” thoughts) and also help with ADHD organization hacks (like breaking tasks down, creating routines). Many find that medication is needed for one or both conditions. Stimulant meds (like methylphenidate or amphetamines) treat ADHD, but in someone with severe anxiety, a stimulant alone can sometimes ramp up the jitters. In fact, children (and adults) with ADHD + anxiety often don't respond as well to ADHD meds unless the anxiety is also addressed. Doctors might add an SSRI or other anti-anxiety medication to the mix, or choose a non-stimulant ADHD med if stimulants prove too anxiety-provoking.Let me share a quick personal strategy (with a dash of humor): I have ADHD and anxiety, so my brain is basically an internet browser with 50 tabs open – and 10 of them are frozen on a spinning “wheel of doom” (those are the anxieties). One practical tip that helps me distinguish the two is to write down my racing thoughts. If I see worries like “I'll probably get fired for sending that email typo” dominating the page, I know anxiety is flaring. If the page is blank because I got distracted after one sentence... well, hello ADHD! This silly little exercise helps me decide: do I need to do some calming techniques, or do I need to buckle down and use an ADHD strategy like the Pomodoro method? Try it out: Knowledge is power, and self-awareness is the key.Quick Tips – ADHD vs Anxiety: When in doubt, ask what's driving the chaos.* Content of Thoughts: Racing mind full of specific worries (anxiety) vs. racing mind full of everything except what you want to focus on (ADHD).* Physical Symptoms: Anxiety often brings friends like sweaty palms, racing heart, and tummy trouble. ADHD's restlessness isn't usually accompanied by fear, just boredom or impulsivity.* Treatment Approaches: For co-occurring cases, consider therapy and possibly a combo of medications. Experts often treat the most impairing symptom first – if panic attacks keep you homebound, address that alongside ADHD. Conversely, untreated ADHD can actually fuel anxiety (ever notice how missing deadlines and forgetfulness make you more anxious? Ask me how I know!). A balanced plan might be, say, stimulant medication + talk therapy for anxiety, or an SSRI combined with ADHD coaching. Work closely with a professional to fine-tune this.Alright, take a breath (seriously, if you've been holding it – breathing is good!). We've tackled anxiety; now let's talk about the dark cloud that can sometimes follow ADHD: depression.ADHD and Depression: When the Chaos Brings a CloudADHD is often associated with being energetic, spontaneous, even optimistic (“Sure, I can start a new project at 2 AM!”). So why do so many of us also struggle with depression? The reality is, living with unmanaged ADHD can be tough. Imagine years of what Dr. Russell Barkley calls “developmental delay” in executive function – always feeling one step behind in managing life, despite trying so hard. It's no surprise that about 1 in 5 kids with ADHD also has a diagnosable depression, and studies show anywhere from 8% to 55% of adults with ADHD have experienced a depressive disorder in their lifetime. (Yes, that range is huge – it depends how you define “depression” – but even on the low end it's a lot.) Dr. Barkley himself notes that roughly 25% of people with ADHD will develop significant depression by adulthood. In short, ADHD can come with a case of the blues (not the fun rhythm-and-blues kind, unfortunately).So what does ADHD + depression look like? Picture this: You've got a pile of unfinished projects, bills, laundry – the ADHD “trail of crumbs.” Initially, you shrug it off or maybe crack a joke (“organizational skills, who's she?”). But over time, the failures and frustrations can chip away at your self-esteem. You start feeling helpless or hopeless: “Why bother trying if I'm just going to screw it up or forget again?” That right there is the voice of depression sneaking in. ADHD's impulsivity might also lead to regrettable decisions or conflicts that you later brood over, another pathway to depressed mood.In fact, the Attention Deficit Disorder Association points out that ADHD's impact on our lives – trouble with self-esteem, work or school difficulties, and strained relationships – can contribute to depression. It's like a one-two punch: ADHD creates problems; those problems make you sad or defeated, which then makes it even harder to deal with ADHD. Fun cycle, huh?Now, depression itself can mask as ADHD in some cases, especially in adults. Poor concentration, low motivation, fatigue, social withdrawal – these can appear in major depression and look a lot like ADHD symptoms. If an adult walks into a doctor's office saying “I can't focus and I'm procrastinating a ton,” a cursory eval might yield an ADHD diagnosis. But if that focus problem started only after they, say, lost a loved one or fell into a deep funk, and they also feel worthless or have big sleep/appetite changes, depression may be the primary culprit. On the flip side, a person with lifelong ADHD might be misdiagnosed as just depressed, because they seem down or overwhelmed. As always, timeline is key: ADHD usually starts early (childhood), whereas depression often has a more defined onset. Also, ask: Is the inability to focus present even when life's going okay? If yes, ADHD is likely in the mix. If the focus issues wax and wane with mood, depression might be the driver.There's also a nuance: ADHD mood issues vs. clinical depression. People with ADHD can have intense emotions and feel demoralized after a bad day, but often these feelings can lift if something positive happens (say, an exciting new interest appears – suddenly we have energy!). Clinical depression is more persistent – even good news might not cheer you up much. As Dr. Thomas Brown emphasizes, ADHD includes difficulty regulating emotion; an ADHD-er might feel sudden anger or sadness that's intense but then dissipates . By contrast, depression is a consistent low mood or loss of pleasure in things over weeks or months. Knowing this difference can be huge in sorting out what's going on.Now, how do we deal with this combo? The good news: many treatments for depression also help ADHD and vice versa. Therapy is a prime example. Cognitive Behavioral Therapy and related approaches can address negative thought patterns (“I'm just a failure”) and also help with practical skills for ADHD (like scheduling, or as I call it, tricking my brain into doing stuff on time). There are even specialized therapies for adults with ADHD that blend mood and attention strategies. On the medication front, sometimes a single med can pull double duty. One interesting option is bupropion (Wellbutrin) – an antidepressant that affects dopamine and norepinephrine, which can improve both depression and ADHD symptoms in some people. There's also evidence that stimulant medications plus an antidepressant can be a powerful combo: stimulants to improve concentration and energy, antidepressant to lift mood. Psychiatrists will tailor this to the individual – for instance, if someone is severely depressed (can't get out of bed), treating depression first may be priority. If the depression seems secondary to ADHD struggles, improving the ADHD could automatically boost mood. Often, it's a balancing act of treating both concurrently – maybe starting an antidepressant and an ADHD med around the same time, or ensuring therapy covers both bases.Let's not forget lifestyle: exercise, sleep, nutrition – these affect both ADHD and mood. Regular exercise, for example, can increase BDNF (a brain growth factor) and neurotransmitters that help both attention and mood. Personally, I found that when I (finally) started a simple exercise routine, my mood swings evened out a bit and my brain felt a tad less foggy. (Of course, starting that routine required overcoming my ADHD inertia – ask me how I know that took a few tries... or twenty.)Quick Tips – ADHD vs Depression:* Check Your Joy Meter: With ADHD alone, you can still feel happy/excited when something engaging happens (ADHD folks light up for interesting tasks!). With depression, even things you normally love barely register. If your favorite hobbies no longer spark any joy, that's a red flag for depression.* All in Your Head? ADHD negative thoughts sound like “Ugh, I forgot again, I need a better system.” Depression thoughts sound like “I forgot again because I'm useless and nothing will ever change.” Listen to that self-talk; depression is a sneaky bully.* Professional Help: A thorough evaluation can include psychological tests or questionnaires to measure attention and mood separately. For treatment, consider a combined approach: therapy (like CBT or coaching) plus meds as needed. According to research, a mix of stimulant medication and therapy (especially CBT) can help treat both conditions. And remember, addressing one can often relieve the other: improve your ADHD coping skills, and you might start seeing hope instead of disappointment (boosting mood); treat your depression, and suddenly you have the energy to tackle that ADHD to-do list.Before we move on, one more important note: if you ever have thoughts of self-harm or suicide, please reach out to a professional immediately. Depression is serious, and when compounded with ADHD impulsivity, it can be dangerous. There is help, and you're not alone – so many of us have been in that dark place, and it can get better with the right support. Knowledge is power and self-awareness is the key, yes, but sometimes you also need a good therapist, maybe a support group, and possibly medication to truly turn things around. There's no shame in that game.Alright, deep breath. It's getting a bit heavy in here, so let's pivot to something different: a condition that seems like the opposite of ADHD in some ways, yet can co-occur – OCD. And don't worry, we'll crank the sass back up a notch.ADHD and OCD: The Odd Couple of AttentionWhen you think of Obsessive-Compulsive Disorder (OCD), you might picture someone extremely organized, checking the stove 10 times, everything neat and controlled. When you think ADHD… well, “organized” isn't the first word that comes to mind, right?

Radically Genuine Podcast
191. Heated Debate with Columbia University Professor of Psychiatry

Radically Genuine Podcast

Play Episode Listen Later Jul 10, 2025 142:43


In this explosive and highly anticipated episode, Dr. Roger McFillin hosts Dr. Ragy Girgis, a Columbia University Professor of Psychiatry and researcher, for a no-holds-barred confrontation that exposes the shocking divisions tearing apart the mental health field. What begins as a conversation about mass violence research rapidly explodes into a devastating examination of psychiatric medicine's crumbling foundations, questionable effectiveness, and devastating potential harms. The two clash in fierce, unrelenting disagreements over fundamental issues including the validity of DSM diagnoses, the debunked "chemical imbalance" theory of depression, dangerous SSRI safety cover-ups and black box warnings, corrupted research quality and pharmaceutical industry manipulation, and the catastrophic crisis of psychiatric drug overprescription poisoning 1 in 4-5 Americans. Dr. Girgis desperately defends traditional academic psychiatry and current treatment approaches, while Dr. McFillin ruthlessly dismantles the entire paradigm, arguing that the current system is systematically creating chronic mental illness rather than healing it. Buckle up for this brutal intellectual warfare.___________________________________________________________________________________________________________________________________________________Throughout the interview, Dr. Girgis repeatedly stated that "the data is clear" while dismissing contradictory evidence that challenges his conclusions. For our listeners' benefit, I have compiled research and documentation that directly disputes several of Dr. Girgis's key claims.Serotonin Hypothesis of Depression1. The serotonin theory of depression: a systematic umbrella review of the evidence (Moncrieff et al.)Conclusions: "This review suggests that the huge research effort based on the serotonin hypothesis has NOT produced convincing evidence of a biochemical basis to depression. This is consistent with research on many other biological markers . We suggest it is time to acknowledge that the serotonin theory of depression is NOT empirically substantiated."2.What has serotonin to do with depression?Conclusions: "Simple biochemical theories that link low levels of serotonin with depressed mood are no longer tenable."3. Is the chemical imbalance an ‘urban legend'? An exploration of the status of the serotonin theory of depression in the scientific literatureViolence & Suicide Associated with SSRI's 1. Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers2. Prescription Drugs Associated with Reports of Violence Towards Others3. Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family4. Lexapro Approved for Pediatric Use Despite the 6-Fold Increase in Suicide Risk5. McFillin Substack Review on Lexapro approved despite Suicide Risk6. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports7. Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect8. Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk:9.  FDA Warning: Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents10.  Suicide Mortality in the United States, 2001–2021 CDC documentation11. US suicide rate reaches highest point in more than 80 years: See what latest data shows12.  CNN article reporting Eli Lilly Internal Documents"An internal document purportedly from Eli Lilly and Co. made public Monday appears to show that the drug maker had data more than 15 years ago showing that patients on its antidepressant Prozac were far more likely to attempt suicide and show hostility than were patients on other antidepressants and that the company attempted to minimize public awareness of the side effects. The 1988 document indicated that 3.7 percent of patients attempted suicide while on the blockbuster drug, a rate more than 12 times that cited for any of four other commonly used antidepressants.In addition, the paper said that 1.6 percent of patients reported incidents of hostility -- more than double the rate reported by patients on any of four other commonly used antidepressants."Examples of Violence after Prescription in legal system (Sample)January 24, 2020 – Newcastle, South Dublin, Ireland: Deirdre Morley, 44, smothered and killed her two sons Conor, 9, and Darragh, 7, and her three-year-old daughter Carla McGinley in their family home. She had been taking antidepressants since October 2018 and was admitted to St. Patrick's Mental Health Services on July 6, 2019, but was discharged after a short period, but was put on a combination of two antidepressants and a sedativeMay 11, 2018 – Osmington, Western Australia: Peter Miles, 61, shot his 35-year-old daughter and four grandchildren, aged 8 through 13, while they slept in their beds, in a shed that had been converted to a second house on the property. He then turned the gun on his 58-year-old wife in the living room of their house, before placing a call to police alerting them to his crimes. When they arrived, Miles was also found dead from a gunshot wound. Miles had started taking antidepressant medication just weeks before.April 6, 2018 – Wadsworth, Ohio: Gavon Ramsay, 17, strangled his neighbor, 98-year-old Margaret Douglas in her own home. His parents blame his actions on his having been misprescribed Zoloft. After a report by his school principal that the teen was depressed and might harm himself, he “returned to therapy,” and after a recommendation by a psychologist, the family's pediatrician prescribed the antidepressant Zoloft. From January through March leading up to the incident, the dosages were increased. During this time, his mother said she observed her son's behavior change—becoming increasingly irritable and hostile and saying bizarre things.October 21, 2013 – Sparks, Nevada: 12-year-old Jose Reyes opened fire at Sparks Middle School, killing a teacher and wounding two classmates be...

Plant Medicine Podcast with Dr. Lynn Marie Morski
Is Psilocybin Safe for Me? with Seth Mehr, MD

Plant Medicine Podcast with Dr. Lynn Marie Morski

Play Episode Listen Later Jul 9, 2025 52:41


In this episode, Seth Mehr, MD joins to share his expertise on safety planning prior to a patient undergoing psilocybin therapy. After a 20 year career as an Emergency Medicine physician, Seth founded Cascade Psychedelic Medicine in 2021, treating clients with depression, anxiety and PTSD with psychedelic ketamine therapy. He also serves as the Health & Safety Director and a state licensed psilocybin facilitator at the Innertrek service center in Portland, Oregon. In this conversation, Dr. Mehr outlines key risk categories for psilocybin therapy: medical conditions, medication interactions, and mental health history. He emphasizes the importance of individualized safety planning over binary yes/no decisions. Dr. Mehr discusses specific considerations such as cardiovascular issues, diabetes, serotonergic medications, substance use disorders, suicidal ideation, and family history of psychosis. The conversation also covers strategies for mitigating risk, including delaying treatment, contingency plans, improving support systems, and ensuring informed consent. Throughout, Dr. Mehr stresses a collaborative, nuanced approach that balances potential benefits with careful preparation and personalized care.   In this episode, you'll hear: Stories from Dr. Mehr's practice of helping patients with different conditions and histories ensure safe psilocybin experiences Interactions between GLP-1 agonists and psilocybin How Dr. Mehr works with patients who have family histories of psychosis Harm reduction practices which leverage other psychedelics or non-psychedelic interventions to help prepare a client for a psilocybin session Why insulin dependent diabetes can be a contraindication for psychedelic therapy What medication combinations can increase the risk of serotonin toxicity with psilocybin  Supporting clients experiencing spiritual emergency following psilocybin therapy Safety considerations when working with clients who have a history of seizures The importance of having contingency plans if medical emergencies arise during psilocybin therapy The intricacies of providing fully informed consent for psychedelic therapy   Quotes: “There is some evidence now that taking a single serotonergic agent—say, taking Lexapro—and no other medications that increase the risk of serotonin toxicity seems safe where I am not at this point recommending that people stop, skip, or taper a single SSRI in preparation for a psilocybin session due to safety.” [12:20] “One of the difficulties with making these decisions or speaking with some confidence or authority on the matter is that the clinical trials that have been done largely exclude people with lots of conditions—family history and specifically first degree relatives with history of psychosis and bipolar disorder… So we have anecdotal evidence, we have population based surveys to go by. And so when I talk to clients about this, I speak from a place of humility.” [27:30] “I always emphasize to clients that while we're talking about a specific safety issue like serotonin toxicity, we don't want to trade that for psychological instability and crisis and declare success because we've helped somebody taper off of a medication that seems less safe and now they aren't sleeping, they're agitated, they're depression is worse, their suicidality is worse. So we have to take a holistic approach to this and consider the totality of what's happening with that client.”  [36:45] “There are so many different components to trying to set somebody up for success rather than a yes/no, black and white approach [to psilocybin therapy].” [48:44]   Links: Cascade Psychedelic Medicine website InnerTrek website Managing Medical Risk In Patients Seeking Psilocybin Therapy CME/CE Course Psychedelic Medicine Association Porangui  

CANADALAND
After Depression Meds, She Lost Her Sexuality

CANADALAND

Play Episode Listen Later Jul 7, 2025 34:38


Emily Grey's been living with a condition known as PSSD for six years now. PSSD can lead to the effective erasure of a person's sexual sensation and functioning.The SSRIs that seem to be at the heart of this condition are selective serotonin uptake inhibitors, a group of antidepressant drugs that have been around for decades. The latest numbers indicate that nearly 20% of Canadian women and 10% of Canadian men are now taking these drugs. It is generally known that potential side effects include a loss of libido. But what we're talking about today and what advocates like Emily have been saying for years is that the side effects can be very extreme. They might persist even after you stop taking SSRIs.We'll also be speaking with Dr. David Healy, a professor of psychiatry at the University of Cardiff in Wales. Dr. Healy has been involved in SSRI research for decades. He's the author of over a dozen books on psychopharmacology, including Let Them Eat Prozac, the Unhealthy Relationship Between The Pharmaceutical Industry and Depression.Also on our panel is Dr. Caroline Pukall professor of psychology at Queen's University whose research focuses on sexual wellbeing and includes sexual psychophysiology.Credits: Host: Jesse BrownCaleb Thompson (Audio Editor), Bruce Thorson (Senior Producer), max collins (Director of Audio), Jesse Brown (Editor and Publisher)Fact checking by Julian AbrahamAdditional music by Audio NetworkFurther ReadingPSSD websiteDr. David HealyDr. Caroline PukallSponsors: oxio: Head over to canadaland.oxio.ca and use code CANADALAND for your first month free! Article: Article is offering our listeners $50 off your first purchase of $100 or more. To claim, visit article.com/canadaland and the discount will be automatically applied at checkoutBetterHelp: Visit betterHelp.com/canadaland today to get 10% off your first month.If you value this podcast, support us! You'll get premium access to all our shows ad free, including early releases and bonus content. You'll also get our exclusive newsletter, discounts on merch at our store, tickets to our live and virtual events, and more than anything, you'll be a part of the solution to Canada's journalism crisis, you'll be keeping our work free and accessible to everybody. You can listen ad-free on Amazon Music—included with Prime. Hosted on Acast. See acast.com/privacy for more information.

A Need To Read
Depression: chemical imbalance or something else? with Joanna Moncrieff

A Need To Read

Play Episode Listen Later Jul 2, 2025 65:09


Today's paid partner is BetterHelp, to get 10% off your first month of online therapy with a credentialed therapist head to www.betterhelp.com/aneedtoread - Today's conversation is with Joanna Moncreiff, the author of 'Chemically Imbalanced: the making and unmaking of the serotonin myth'. We discuss the history of the link between depression and serotonin, side effects of taking SSRI's and the emerging mental health treatment methods that we should be wary of.    For help understanding how you can come off Anti Depressants, follow this link  -    A Need To Read is partnered with The Breath Space, a online Breath-work education and practise portal that I have been using for the last couple of months, alongside my course to become a breath-work facilitator. To check out how breathwork can help you, follow the link and use the code ED for 50% off your first 2 months.  https://courses.thebreathspace.co.uk/your-breath-space-online-membership    You can also support my work by heading to www.buymeacoffee.com/aneedtoread    Any feedback is welcome: aneedtoread.podcast@gmail.com 

Expert Network Team
SSRI For Everyone Including Pensioners

Expert Network Team

Play Episode Listen Later Jul 1, 2025 35:28


Social Security Retirement Income has some good news–no kidding–and we invite expert Chad Harmon to discuss the details. Previously, public pensioners like government employees, schoolteachers, police officers, firefighters and more, received either no Social Security Retirment Income or had their benefits severely reduced. Now, they can earn more. Learn who this affects, how much it affects them, and how you or someone you love could benefit.2.5 to 3 million may benefit from SSRI improvements. Who will benefit the most? What might you be able to do to take advantage of these additional benefits? And check in at the end to know what you may need to do if you have never bothered to register with the SSRI in the past.As a quick reminder, the Expert Network Team provides free consultations. We would love the opportunity to be of service to you or someone you care about. Just scroll the liner notes to contact one of our experts or today's guest. And please share this podcast with anyone who you think might find it interesting.As always, it is good to have an expert on your side.— Our guest:Chad HarmonPartner, A&I Wealth Management(303) 690.5070chad@assetsandincome.com Expert Network team provides free consultations. Just mention that you listened to the podcast. Nathan Merrill, attorneyWorking with affluent families and entrepreneurs in implementing tax-efficient strategies and wealth preservationGoodspeed, Merrill(720) 473-7644nmerrill@goodspeedmerrill.comwww.goodspeedmerrill.com Jeff Krommendyk, Insurance ExpertWorking with business owners and successful families in transferring riskOne Digital Insurance Agency(303) 730-2327jeff.krommendyk@onedigital.com Karl FrankFinancial planner helping a small number of successful families grow and protect their wealth and choose how they want to be taxedCERTIFIED FINANCIAL PLANNER™A&I Wealth Management(303) 690.5070karl@assetsandincome.com Webcasts, Podcasts, Streaming Video, Streaming AudioA&I webcasts, podcasts, streaming video, or streaming audios are provided free of charge solely for use by individuals for personal, noncommercial uses, and may be downloaded for such uses only, provided that the content is not edited or modified in any way and provided that all copyright and other notices are not erased or deleted.All webcasts, podcasts, streaming video, or streaming audios are subject to and protected by U.S. and international copyright laws and may not be sold, edited, modified, used to create new works, redistributed or used for the purpose of promoting, advertising, endorsing or implying a connection with A&I.A&I reserves the right, at any time and for any reason, to stop offering webcasts, podcasts, streaming video, or streaming audios and to stop access to or use of webcasts, podcasts, streaming video, or streaming audio and any content contained therein A&I shall not be liable for any loss or damage suffered as a result of, or connected with, the downloading or use of the webcasts, podcasts, streaming video, or streaming audios. A&I Wealth Management is a registered investment adviser that only conducts business in jurisdictions where it is properly registered, or is excluded or exempted from registration requirements. Registration as an investment adviser is not an endorsement of the firm by securities regulators and does not mean the adviser has achieved a specific level of skill or ability. The firm is not engaged in the practice of law or accounting.The information presented is believed to be current. It should not be viewed as personalized investment advice. All expressions of opinion reflect the judgment of the presenter on the date of the podcast and are subject to change. The information presented is not an offer to buy or sell, or a solicitation of any offer to buy or sell, any of the securities discussed. You should consult with a professional adviser before implementing any of the strategies discussed. Any legal or tax information provided in this podcast is general in nature. Always consult an attorney or tax professional regarding your specific legal or tax situation.

SURVIVING HEALTHCARE
341. Liugi Magione, the alleged UnitedHealthcare CEO shooter, was said to be taking an SSRI antidepressant prescribed for irritable bowel…

SURVIVING HEALTHCARE

Play Episode Listen Later Jun 30, 2025 39:08


BS Free MD with Drs. May and Tim Hindmarsh
375— Dr. Adam Urato on Obstetric Drugs That Harm Mothers and Babies

BS Free MD with Drs. May and Tim Hindmarsh

Play Episode Listen Later Jun 26, 2025 82:38


Dr. Adam Urato grew up in Framingham, Massachusetts—and returned to serve the same hospital he was born in. But over the course of his career as a maternal-fetal medicine specialist, he discovered a troubling truth: much of what passes for “standard of care” in obstetrics isn't grounded in good science—it's driven by pharmaceutical profit.In this gripping episode, Dr. Urato unpacks the decades-long use of Makena, a drug prescribed to prevent preterm birth that was ultimately pulled after being proven ineffective. He details how the same pattern of flawed trials, exaggerated benefits, and minimized risks is playing out again with SSRI use during pregnancy—putting fetal brain development at risk without informed consent.Together with hosts Drs. May and Tim Hindmarsh, Dr. Urato questions the systems that keep patients in the dark, the media silenced, and doctors bound by legal handcuffs to outdated protocols. He reminds us that medications are chemicals—and chemicals have consequences, especially during pregnancy.If you've ever trusted a prescription without questioning where the science really comes from, this episode might just change the way you see modern medicine.Our Advice!Everything in this podcast is for educational purposes only. It does not constitute the practice of medicine and we are not providing medical advice. No Physician-patient relationship is formed and anything discussed in this podcast does not represent the views of our employers. The Fine Print!All opinions expressed by the hosts or  guests in this episode are solely their opinion and are not to be used as specific medical advice.  The hosts,  May and Tim Hindmarsh MD, BS Free MD LLC, or any affiliates thereof are not under any obligation to update or correct any information provided in this episode. The guest's statements and opinions are subject to change without notice.Thanks for joining us! You are the reason we are here.  If you have questions, reach out to us at doc@bsfreemd.com or find Tim and I on Facebook and IG.Please check out our every growing website as well at  bsfreemd.com (no www) GET SOCIAL WITH US!We're everywhere here: @bsfreemd 

The Pet Behaviour Chat
088 Serotonin Syndrome - What you need to know!

The Pet Behaviour Chat

Play Episode Listen Later Jun 23, 2025 31:14


Episode 88 – Serotonin Syndrome - What you need to know!   Serotonin Syndrome, also known as Serotonin Toxicity, is the most severe side effect of serotonergic medication and can potentially be fatal if not treated and managed. Therefore, understandably, many vets are very cautious when it comes to prescribing serotonergic agents and especially when combining serotonergic agents such as an SSRI and, for example, trazodone. ·         But, how frequent is this side effect in practice? ·         What are the signs you should be looking out for? ·         What can you teach your caregivers to do in terms of monitoring to screen for mild signs of Serotonin Syndrome? ·         What medications, aside from psychopharmaceutical medications, can cause Serotonin Syndrome? ·         What are the Differential Diagnoses for Serotonin Syndrome? ·         And how do you treat a pet with Serotonin Toxicity?   I talk about all this and more in this episode!   Here are the studies I mention in the episode: 1.      Indrawirawan, Y., & McAlees, T. (2014). Tramadol toxicity in a cat: Case report and literature review of serotonin syndrome. Journal of Feline Medicine and Surgery, 16(7), 572–578. https://doi.org/10.1177/1098612X14539088   2.      Pugh, C. M., Sweeney, J. T., Bloch, C. P., Lee, J. A., Johnson, J. A., & Hovda, L. R. (2013). Selective serotonin reuptake inhibitor (SSRI) toxicosis in cats: 33 cases (2004-2010). Journal of Veterinary Emergency and Critical Care, 23(5), 565–570. https://doi.org/10.1111/vec.12091   3.      Thomas, D. E., Lee, J. A., & Hovda, L. R. (2012). Retrospective evaluation of toxicosis from selective serotonin reuptake inhibitor antidepressants: 313 dogs (2005-2010). Journal of Veterinary Emergency and Critical Care, 22(6), 674–681. https://doi.org/10.1111/j.1476-4431.2012.00805.x   If you'd like to learn more about Veterinary Psychopharmacology, then my PSYCHOACTIVE course is for you! Follow the link below to get access to PSYCHOACTIVE – PRACTICAL VETERINARY PSYCHOPHARMACOLOGY Use SUMMER50 for a 50% Discount this summer 2025!   https://katrin-jahn.mykajabi.com/psychoactive   If you liked this episode of the show, The Pet Behaviour Chat, please LEAVE A 5-STAR REVIEW, like, share, and subscribe!   Facebook Group: Join The Veterinary Behaviour Community on Facebook   You can CONNECT with me: Website: Visit my website Trinity Veterinary Behaviour Instagram: Follow Trinity Veterinary Behaviour on Instagram Trinity Veterinary Behaviour Facebook: Join us on Trinity Veterinary Behaviour's Facebook page Trinity Veterinary Behaviour YouTube: Subscribe to Trinity Veterinary Behaviour on YouTube LinkedIn Profile: Connect with me on LinkedIn   Thank you for tuning in!

Vitality Radio Podcast with Jared St. Clair
#545 VR Vintage: The Natural Approach to Mental Health: How To Optimize Mood and Reduce Anxiety With Lifestyle and Supplements

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Jun 21, 2025 44:29


This episode originally aired as #327 on 5/20/23. It's an oldie but goodie so we are sharing it again! Mental Health is a mounting issue in America today.  Pharma prescriptions are higher than ever before, more people are in therapy than ever before and more than ever, people are searching for alternatives to those methods. On today's episode Jared runs through what he considers to be the foundational things that you should consider to improve your mental health. You will learn about the gut brain connection, deficiencies that impact mental health, the value of breath, sleep, water,  sunshine and more.Products:Precision Probiotic Vital SporesVital 5 Magnesium BisglycinateVital 5 Ultimate Vitality Multi-VitaminBioCoenzymated Active B ComplexVital 5 Omega 3 + AntioxidantsUltra Strength RX Omega 3Sensoril AshwagandhaAnxiety ReleaseVital SleepL-Theanine chewables Additional Information:Episode #164: Psychobiotics - Unique Probiotics for Depression, Anxiety and More Part 1Episode #166: Psychobiotics - Unique Probiotics for Depression Anxiety and More Part 2Episode #306: The Great Debate in Probiotics: Human Strains vs. SporesEpisode #258: Your Magnesium Users GuideEpisode #264: Jen's Story: How One Woman Fought Through Addiction, Mental and Physical Illness to Find Vitality.Episode #265: Sleep! Your Guide to Falling Asleep, Staying Asleep and Deeper and More Restful SleepVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

The David Knight Show
Wed Episode #2035: The Medical Industrial Complex Is Making Us Sicker by Design

The David Knight Show

Play Episode Listen Later Jun 18, 2025 185:59


[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

The REAL David Knight Show
Wed Episode #2035: The Medical Industrial Complex Is Making Us Sicker by Design

The REAL David Knight Show

Play Episode Listen Later Jun 18, 2025 185:59


[01:23:16 – 01:27:24] — Cholesterol Myth, Statins, and Cognitive Decline Refutes the link between cholesterol and heart disease, critiques the use of statins, and explains how they contribute to memory loss by impairing mitochondrial function. [01:40:53 – 01:43:33] — Spike Protein Damage and Fertility Concerns Links mRNA vaccine-induced spike protein accumulation in reproductive organs to a global fertility crisis, citing observed autoimmune diseases and turbo cancer cases post-vaccination.[01:53:29 – 01:58:27] — Treating Vaccine Clotting with Enzymes and NAC Outlines a protocol using enzymes like lumbrokinase and an enhanced NAC formulation to reverse microclotting and spike protein persistence in long-haul COVID patients.[01:58:29 – 01:59:39] — Bacteriophages and Antibiotic Resistance Praises bacteriophage therapy as a targeted alternative to antibiotics and criticizes its abandonment in favor of pharmaceuticals, linking this to rising antimicrobial resistance.[02:01:26 – 02:04:38] — SSRIs, Mental Health, and Nutrient Deficiencies Critiques widespread SSRI prescriptions, emphasizing magnesium, iodine, and vitamin D deficiencies as underlying causes of depression and anxiety in young patients.[02:14:43 – 02:17:31] — SSRI Withdrawal, Loneliness, and Atheism Trends Explores the challenges of getting off SSRIs, with emphasis on individualized treatment and social patterns such as loneliness, atheism, and lack of purpose among depressed patients.[02:26:27 – 02:29:41] — Immune System Boosting and Sunshine Debate Advocates sunlight and antioxidant synergy (e.g. ALA, vitamin C, CoQ10) as immune boosters; challenges conventional views on sunlight causing skin cancer, linking melanoma instead to lack of sun exposure.[02:31:28 – 02:40:14] — DMSO and Boron for Pain, Bone, and Hormonal Health Promotes DMSO combined with boron for arthritis and testosterone boosting; includes detailed background on absorption, safety, and additional applications.[02:40:15 – 02:45:19] — Leaky Gut as Root of Autoimmune Disease Describes how gluten-related intestinal damage can lead to autoimmune diseases like rheumatoid arthritis and Hashimoto's; outlines a multi-supplement gut-healing protocol.[03:00:25 – 03:03:54] — Medical Industrial Complex and Generational Health Decline Critiques a profit-driven healthcare model that fosters chronic illness for repeat business and links rising childhood illness and birth defects to vaccine exposure and poor nutrition.[03:06:12 – 03:17:16] — Thyroid Dysfunction and Comprehensive Testing Approach Explains the biochemical complexity of thyroid function and criticizes mainstream thyroid testing, advocating for broader lab panels and natural hormone therapies.[03:20:16 – 03:23:19] — Blue Light, Circadian Rhythm, and Melatonin Suppression Describes how artificial lighting and sunglasses disrupt melatonin production, emphasizing the need for natural sunlight exposure and avoidance of electronics during sleep.[03:48:28 – 03:52:20] — Economic Collapse, Oil Crisis, and CBDC Transition Argues that current global conflict and economic chaos are engineered to collapse the dollar, spike oil prices, and drive public acceptance of central bank digital currencies.[03:59:24 – 04:00:05] — Grassroots Support for Independent Media Encourages community-driven funding of alternative media, rejecting corporate censorship and highlighting the role of listener support in sustaining truthful broadcasting. Follow the show on Kick and watch live every weekday 9:00am EST – 12:00pm EST https://kick.com/davidknightshow Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code KNIGHT Find out more about the show and where you can watch it at TheDavidKnightShow.comIf you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

The Bright Side
Finding Your Voice Again with Rachel Platten

The Bright Side

Play Episode Listen Later Jun 16, 2025 39:07 Transcription Available


Rachel Platten became a global force with Fight Song, but few know the silent battle she's fought behind the scenes. In this powerful and deeply personal conversation, Rachel and Simone share raw, unfiltered stories of motherhood, mental health, and finding your voice again. This is Rachel, like you’ve never heard her—vulnerable, luminous, and rooted in a whole new strength.See omnystudio.com/listener for privacy information.

The Pediatrician Next Door
Bonus Episode: Medication for Anxiety and Depression – Finding the Balance

The Pediatrician Next Door

Play Episode Listen Later Jun 13, 2025 9:14


Explore the role of medication in treating anxiety and depression in kids and teens. When can it help—and how do you decide? Psychiatrist Julia Krankl, MD, returns to share guidance for parents on when to consider medication and what to expect if your child starts an SSRI or other treatment. If you're feeling unsure or even nervous, this episode offers clarity, reassurance, and insights on finding the right balance between therapy, lifestyle changes, and meds.    Guest Julia Krankl, MD - Read her book: The 21st Minute: Everything you Wished Doctors Explained about Mental Health     Send your questions to hello@pediatriciannextdoorpodcast.com or submit at drwendyhunter.com  Find products from the show on the shop page.   *As an Amazon Associate, I earn commission from qualifying purchases.    More from The Pediatrician Next Door:    Website: drwendyhunter.com   Instagram: @the_pediatrician_next_door  Facebook: facebook.com/wendy.l.hunter.75  TikTok: @drwendyhunter  LinkedIn: linkedin.com/in/drwendyhunter    This is a Redd Rock Music Podcast  IG: @reddrockmusic  www.reddrockmusic.com Learn more about your ad choices. Visit megaphone.fm/adchoices

The Carnivore Yogi Podcast
The Truth About Methylene Blue: Mood, Mitochondria + More | Dr. Scott Sherr

The Carnivore Yogi Podcast

Play Episode Listen Later Jun 11, 2025 63:51


Methylene Blue has been getting a lot of attention lately, and I wanted to cut through the noise with some real science. I sat down with my friend Dr. Scott to talk about why this compound might actually be a powerful and supportive tool for mitochondrial health, brain function, and overall vitality.Some recent conversations have raised questions about Methylene Blue, so we're here to bring clarity and context. In this episode, we break down the research, talk through safety considerations, and explore why Methylene Blue might be one of the most underrated interventions out there.TOPICS DISCUSSED→ What are the benefits of Methylene Blue for the brain and cells?→ What does current research say about Methylene Blue?→ Who shouldn't use Methylene Blue, especially with SSRIs?→ How does Methylene Blue boost energy and clarity?→ Is Methylene Blue safe for brain and energy support?TIMESTAMPS→ 00:00:00 - Introduction → 00:01:55 - Is Methlyne Blue dangerous? → 00:05:54 - Methlyne Blue dosing → 00:08:03 - Troches & titration → 00:09:57 - Therapeutic benefits of Methylene Blue→ 00:15:05 - Cells with the most mitochondria → 00:18:40 - SSRIs and other Methylene Blue contraindications→ 00:23:39 - Supplement cycling→ 00:27:49 - SSRI's dopamine and Norepinephrine→ 00:34:30 - Methylene Blue & metabolism → 00:35:29 - Mitochondria dysfunction & stress → 00:38:21 - The dangers of blue light → 00:43:30 - The science of Methalyne blue → 00:47:41 - Daily Methalyne Blue usage → 00:51:43 - Red light and Methalyne Blue  → 00:53:12 - Methylene Blue, energy, & sleep → 00:55:07 - How to take Methylene Blue→ 00:59:13 - Resources for clinicians and practitioners SPONSORED BY:→ Troscriptions | There's a completely new way to optimize your health. Give it a try at troscriptions.com/SARAHK, or enter SARAHK at checkout for 10% off your first order.SHOW LINKS:→ The Ultimate Methylene Blue Episode - What Is It & Can It Give Me More Energy? Dr. Scott SherrCheck Out Dr Scott: → Troscriptions | There's a completely new way to optimize your health. Give it a try at troscriptions.com/SARAHK, or enter SARAHK at checkout for 10% off your first order.→ Podcast→ Instagram This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________My free product guide with all product recommendations and discount codes:https://s3.amazonaws.com/kajabi-storefronts-production/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdfCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! -https://www.sarahkleinerwellness.com/contact

Smoke 'Em If You Got 'Em Podcast
205. Brooke Siem on Medicating Unhappiness and SSRI Withdrawal

Smoke 'Em If You Got 'Em Podcast

Play Episode Listen Later Jun 5, 2025 24:25


This is a free preview of a paid episode. To hear more, visit smokeempodcast.substack.comBrooke Siem is the author of the 2022 memoir, May Cause Side Effects, about the decade and a half she spent on anti-depressants (prescribed after her father died when she was 15) and what happened when she ditched them. Sarah is currently on anti-depressants, though she wonders whether she needs them. Nancy is not on SSRIs, though she was part of a gentle brigade who nudged Sarah to increase her dosage last year. This is a complicated knot! The ladies talk about over-medication, how cultural taboos migrate, and the problem with treating sadness, anger, frustration — very human emotions — with a pill. Also discussed:* Nancy suddenly cares about the Navy; Sarah questions this* That time Brooke wore a foxy denim jumper* “Chemical imbalance” is a hoodwink* The “Come Out of the Dark Campaign” meant to eradicate depression stigma leads to an explosion of SSRI prescriptions* SSRIs and orgasm* The opiate epidemic tracks with the anti-depressant era * “Chemical castration” didn't start with puberty blockers …* 70s-80s Ritalin vogue* Related: Does Ritalin suppress male growth?* Hold up: a link between transitioning genders and SSRIs?* Drinking and depression, a tangled saga* “Headaches are caused by an Advil deficiency”* Beware Wellbutrin* Gothic SSRI withdrawal* “I never boned a cabbie … that I'm aware of.”* That time Sarah went hypomanic …* 1 in 4 American women are on anti-depressants* The hormones and menopause of it all* “Fuck you, person at Whole Foods!”* Big Pharma / Big Food = same playbook, different expression* “Do you bake with yeast?”* WTF with Pol Pot?Plus, boozy cupcakes, a coyote sighting, was Tom Cruise right about pharmaceuticals — and much more!This one's a banger! Listen to the whole shebang when you become a paid subscriber.

Mind & Matter
SSRIs, Sexual Dysfunction, Suicide & Mass Shootings, How FDA Works | David Healy | 232

Mind & Matter

Play Episode Listen Later Jun 5, 2025 130:09


Send us a textA critique of SSRIs and pharma's influence on medicine, including SSRI-induced sexual dysfunction, suicidality, and violence. Long Summary: Dr. David Healy critiques modern medicine, focusing on SSRIs and psychiatric medicine, including: how pharmaceutical companies manipulate clinical trial data, ghostwrite studies, and influence medical practice, often ignoring patient experiences; highlighting issues like post-SSRI sexual dysfunction (PSSD), the immediate sensory effects of SSRIs, and their potential to induce suicidal or violent behavior; challenging the reliance on randomized controlled trials (RCTs) over individual patient reports; and more.About the guest: David Healy, MD, PhD, a psychiatrist and pharmacologist, has decades of experience researching the serotonin system and SSRIs, working across Ireland, the UK, Canada, and the US. He is a professor at McMaster University and a vocal critic of pharmaceutical industry practices.Discussion Points:SSRIs cause near-immediate sensory effects, like genital numbing, in most people.Post-SSRI sexual dysfunction (PSSD) can persist for years or decades after stopping the drug, affecting many long-term users.Healy argues RCTs prioritize averages over individual experiences, often missing serious side effects like suicidality.Pharmaceutical companies ghostwrite studies and manipulate data, with journals like the New England Journal of Medicine publishing misleading articles.Serotonin theory of depression lacks evidence.Industry tactics include dismissing patient reports as anecdotes and using high doses in trials to mask weak efficacy.SSRIs can increase suicide risk, not just during initiation but also when adjusting doses or withdrawing, as seen in cases like the Aurora movie theater shooting.Regulatory bodies like the FDA often fail to investigate adverse effects due to bureaucratic processes and lack of follow-up.Healy emphasizes doctors' failure to prioritize patient observations, driven by industry-influenced standards of care.Related episode:M&M 88: Depression, Serotonin, SSRIs, Psychiatry & Social Media | Joanna Moncrieff*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

The Highwire with Del Bigtree
Episode 426: PESTICIDES, PILLS AND POLITICS

The Highwire with Del Bigtree

Play Episode Listen Later Jun 2, 2025 124:01


Moms Across America founder Zen Honeycutt on the growing pesticide crisis—and how the MAHA movement plans to take action; Jefferey Jaxen details the MAHA Commission's 100-day report, the exploitation of autistic children within the medical system, and a must-see update on the WHO's looming Pandemic Treaty; Dr. Adam Urato shares alarming new findings on SSRI antidepressants and how prenatal exposure may be harming fetal brain development.Don't miss this critical episode.Guests: Zen Honeycutt, Adam Urato, M.D.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

Misery Loves Mandy
Misery Loves Mental Health | EP 146

Misery Loves Mandy

Play Episode Listen Later May 28, 2025 74:03


They are miserable about the stigma that antidepressants kill creativity, performance anxiety, and the struggle to stay productive without burning out.In this special episode of 'Misery Loves Mandy' for Mental Health Awareness Month, Mandy sits down with Macey Isaacs and Bijan Zarrabi, hosts of the podcast 'SSRI'M OK.' The discussion covers a wide range of topics, including mental health, depression, anxiety, and the stigmas associated with these conditions. Bijan, a psychiatrist, shares professional insights while the group also explores the intersection of mental health and creativity, how antidepressants affect people, and tips for achieving a balance between personal life and professional ambitions. Tune in for an engaging and informative conversation that also touches on personal anecdotes and the challenges of life in comedy.

Quick Smart
One in seven of us take antidepressants. Getting off them can be a nightmare

Quick Smart

Play Episode Listen Later May 26, 2025 10:44


Chances are you, or someone you know, took an antidepressant this morning. One in seven Australians are on the medication, and for many it's lifesaving. But are we staying on antidepressants for too long? Is there a right time to stop? And what should we know about withdrawal symptoms? 

Boost Your Biology with Lucas Aoun
318. DHT Is Incredibly Important - Here's Why!

Boost Your Biology with Lucas Aoun

Play Episode Listen Later May 21, 2025 49:01


In this episode of the Boost Your Biology podcast, Lucas Aoun interviews Miro Henzel, a biohacker and YouTuber, who shares his personal journey of overcoming hormonal issues and the importance of understanding the risks associated with supplements. They discuss the effects of finasteride and other DHT blockers, explore natural alternatives like Catuaba, and emphasize the significance of diet and lifestyle choices in optimizing testosterone levels. The conversation also touches on the role of coffee in hormonal health and the balance between enjoying life and maintaining health. In this conversation, Miro and Lucas delve into various aspects of health optimization, focusing on individual responses to coffee, the importance of quality in dietary fats, common mistakes in testosterone management, the role of DHT, managing prolactin levels, and addressing post-SSRI sexual dysfunction. They emphasize the significance of testing and understanding personal health needs, as well as the careful selection of supplements to enhance well-beingRelevant links:Miro Henzel's YouTube:https://www.youtube.com/@biohackingformenMiro's Email:mirohenzel@gmail.comCheck Out My Website For Coaching, Recommended Products and Much More:https://www.boostyourbiology.com/ Disclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program.Chapters00:00 Introduction to Biohacking and Personal Journey02:49 The Risks of Supplements and Hormonal Health05:11 Understanding Finasteride and Its Side Effects07:29 The Long-Term Effects of DHT Blockers10:12 Exploring Natural Alternatives: Catuaba and Other Herbs12:29 Key Supplements for Hormonal Health15:27 Dietary Considerations for Testosterone Optimization18:54 The Role of Coffee in Hormonal Health23:11 Balancing Enjoyment and Health24:55 Understanding Individual Responses to Coffee27:55 The Importance of Quality in Fats and Oils29:16 Common Mistakes in Testosterone Management32:56 The Role of DHT in Hormonal Health35:46 Managing Prolactin Levels for Better Health40:44 Addressing Post-SSRI Sexual Dysfunction45:36 Final Thoughts on Supplements and Health Hosted on Acast. See acast.com/privacy for more information.

Your Lot and Parcel
The Insidious Nature of SSRI Antidepressants

Your Lot and Parcel

Play Episode Listen Later May 15, 2025 47:23


 A tragedy made it more terrible by how preventable it was. It is urgent that this story be told and widely shared, given the tidal wave of depression and anxiety disorders that has washed over the United States in the wake of the COVID-19 pandemic, especially among young people. That tidal wave, combined with the overprescribing of powerful brain-altering medications and the widespread lack of awareness about the potentially lethal side effects of these drugs, is a prescription for disaster.This is a heartbreaking story of filicide, the potential risks of powerful antidepressants, and unforgiving justice with respect to crimes involving mental illness.He is the author of "Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins." https://www.amazon.com/Medication-Mental-Illness-Murder-Really/dp/1538199297http://www.yourlotandparcel.org

Relatable with Allie Beth Stuckey
Ep 1189 | SSRIs Are Rewiring Babies' Brains — and Killing Their Moms | Guest: Dr. Adam Urato

Relatable with Allie Beth Stuckey

Play Episode Listen Later May 14, 2025 68:52


Today, we're chatting with Dr. Adam Urato, a fetal and maternal medicine specialist, to discuss the lack of informed consent given to pregnant women concerning certain medications they're taking, namely SSRI antidepressants. Dr. Urato tells us about the crucial role serotonin plays in fetal development and the negative effects that SSRI use in pregnancy can have on an unborn baby. We also discuss the increase in medical interventions in pregnancy in recent decades and how these interventions may not be as positive as they seem. And is the pharmaceutical industry to blame for doctors' lack of concern over SSRI use? This episode is brought to you by Olive, the app built for the MAHA movement. Download the Olive app now to see what toxins are hiding in your groceries. Share the Arrows 2025 is on October 11 in Dallas, Texas! Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠sharethearrows.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for tickets now! Buy Allie's new book, "Toxic Empathy: How Progressives Exploit Christian Compassion": ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/4COtBxy⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Timecodes: (01:50) Dr. Urato introduction (04:12) Over-intervention in pregnancy (15:27) Medication safety in pregnancy (29:07) Lack of medical concern (34:50) SSRI effects on fetal development (46:32) Doctors avoiding catastrophe (51:48) Postpartum SSRI use (58:34) What is the FDA's role?  (01:00:58) Dr. Urato's criticism of Makena --- Today's Sponsors: Seven Weeks — Experience the best coffee while supporting the pro-life movement with Seven Weeks Coffee; use code ALLIE at ⁠⁠https://www.sevenweekscoffee.com⁠⁠ to save up to 25% off your first order, plus your free gift! Good Ranchers — Go to https://GoodRanchers.com and subscribe to any of their boxes (but preferably the Allie Beth Stuckey Box) to get free bacon, ground beef, seed oil free chicken nuggets, or wild-caught salmon in every box for life. Plus, you'll get $40 off when you use code ALLIE at checkout. Hillsdale College — Hillsdale College is offering more than 40 free online courses they offer on History, Economics, Politics, Philosophy, and more, including their new course, "Understanding Capitalism," all available for FREE. Go to https://hillsdale.edu/relatable to enroll. A Faith Under Siege — Watch the explosive new film "A Faith Under Siege: Russia's Hidden War on Ukraine Christians," detailing the persecution of believers under Russia's expanding occupation. Go to faithundersiege.com to watch today. --- Related Episodes: Ep 821 | Why Antidepressants Don't Fix Depression | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-821-why-antidepressants-dont-fix-depression-guest/id1359249098?i=1000616890403 Ep 822 | The Big Money Behind Big Medicine | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-822-the-big-money-behind-big-medicine-guest-dr/id1359249098?i=1000617050991 Ep 1031 | Psychiatry Is Killing People | Guest: Dr. Roger McFillin https://podcasts.apple.com/us/podcast/ep-1031-psychiatry-is-killing-people-guest-dr-roger/id1359249098?i=1000661830317 Ep 650 | COVID Comeback, Depression Meds, & Alzheimer's Scandal | Guest: Dr. Jay Bhattacharya https://podcasts.apple.com/us/podcast/ep-650-covid-comeback-depression-meds-alzheimers-scandal/id1359249098?i=1000571375454 Ep 983 | What Doctors Aren't Telling You About Antidepressants | Guest: Brooke Siem https://podcasts.apple.com/us/podcast/ep-983-what-doctors-arent-telling-you-about-antidepressants/id1359249098?i=1000652056518 --- Buy Allie's book, You're Not Enough (& That's Okay): Escaping the Toxic Culture of Self-Love: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://alliebethstuckey.com/book⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Relatable merchandise – use promo code 'ALLIE10' for a discount: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://shop.blazemedia.com/collections/allie-stuckey Learn more about your ad choices. Visit megaphone.fm/adchoices

The Clinician's Corner
#50: Brendan Vermeire - Brain on Fire: A Root-Cause Approach to Mental Health Disorders

The Clinician's Corner

Play Episode Listen Later May 13, 2025 53:13 Transcription Available


In this episode of the RWS Clinician's Corner, Margaret and Brendan explore the powerful connection between metabolic health and mental well-being, revealing why mental health isn't just about psychology—but also about our biology. Brendan breaks down his “three pillars” model for true mental wellness, walks us through nuanced approaches to lab testing, and explains why functional practitioners should be both evidence-based and deeply empathetic.    In this interview, we discuss:  Brendan's early experiences with mental health struggles and his challenges with the conventional psychiatric approaches  The importance of distinguishing between psycho-emotional issues and neurological/physiological health The role of objective biomarkers in validating client experiences, as well as the potential pitfalls of over-identification with laboratory findings  Recognizing when to refer clients to mental health professionals  Techniques for addressing emotionally charged or traumatic material during sessions The Clinician's Corner is brought to you by Restorative Wellness Solutions.  Follow us: https://www.instagram.com/restorativewellnesssolutions/ Note: This episode contains discussions about suicide, which may be distressing to some listeners. Please take care of yourself and feel free to pause or skip this episode if needed. If you, a client, or someone you know is struggling with thoughts of suicide, help is available. Here is a list of free, confidential resources available 24/7: 988 Suicide & Crisis Lifeline: Call or text 988, or chat online at 988lifeline.org      -Crisis Text Line: Text HOME to 741741 to connect with a trained counselor      -The Trevor Project (for LGBTQ+ youth): Call 1-866-488-7386 or text START to 678-678 These services are here to support you anytime, anywhere. Remember, reaching out for help is a sign of strength.   Connect with Brendan Vermeire: Website: www.metabolicsolutionsllc.com Instagram: https://www.instagram.com/the_holistic_savage/   Use the discount code RW25 to get Brendan's FMHP Workshop Series for FREE: https://holisticsavage.kartra.com/page/FMHP-workshop   Timestamps:  00:00 "Functional Mental Health Insights" 05:46 "Passion for Healing Amid Struggle" 10:01 "Bridging Science with Spiritual Fitness" 13:28 "Mind-Body Connection Explored" 16:31 Objective Biomarkers vs. Mysterious Diagnoses 19:22 Navigating Functional Medicine Challenges 21:09 Mycotoxin Tests: Limited Diagnostic Insight 27:17 Neuroinflammation and Immune Biomarkers 30:11 Rethinking Lab Test Investments 32:52 Clinical Intake and Lifestyle Assessment 36:29 "Effective Patient Engagement Strategies" 41:13 Essential Advice for Health Practitioners 43:21 Bridging Coaching and Functional Medicine 46:14 "Understanding Test Limitations in Health" 49:43 Functional Mental Health Training Program 52:24 "Listener Requests and Gratitude" Speaker bio: Brendan Vermeire is a Clinical Researcher, Functional Medicine Practitioner & Educator, passionate about teaching a root-cause approach to mental and metabolic Illness. He is the proud owner of the Metabolic Solutions Institute, home of the Functional Mental Health Practitioner Certificate Program.   Keywords: metabolic health, mental health, functional medicine, biomarkers, neurological health, psycho-emotional health, lab testing, suicidal ideation, root cause medicine, functional practitioners, SSRI, psychiatric drugs, metabolic markers, personal training, clinical research, depression, anxiety, neuroinflammation, microbiome, mindset, metabolic dysfunction, mold illness, mycotoxins, stool testing, coaching, motivational interviewing, C-reactive protein, neurofilament light chain, neurotransmitters, patient compliance   Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Un Poquito Podcast
ASMR U SERIOUS Feat Mikaela | EP 9 | REYDAR

Un Poquito Podcast

Play Episode Listen Later May 8, 2025 69:51


Autism, burnout, bug pinning, and bubblegum. We talk garden identity, TikTok spirals, anti-SSRI philosophy, and the stand-up stage as sensory battlefield. There's soy discourse, ceramic trivia, Play-Doh betrayal, and a lot of misophonia. Comedy gets dissected. So does voice. Also: the CIA is in the comments. Thank you all for Listening!  Follow Mikaela : https://linktr.ee/MiMikaela Follow Us: Podcast pages - https://linktr.ee/reydarpod https://www.instagram.com/reydarpodcast Rian Reyes - https://linktr.ee/rianreyes Josh the Producer - https://www.instagram.com/imjoshuabenjamin Support the podcast: Patreon - https://patreon.com/reydarpod Merch - https://www.etsy.com/shop/RiansMerch  Legacy Teas and Spices: https://legacyteasandspices.com Use code: rian20

New Books Network
Edward L. Jones III, "Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins?" (Rowman & Littlefield, 2025)

New Books Network

Play Episode Listen Later May 6, 2025 67:56


While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as "the perfect life." She and her husband, David--a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance--had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

New Books in Medicine
Edward L. Jones III, "Medication, Mental Illness, and Murder: What Really Killed the Crespi Twins?" (Rowman & Littlefield, 2025)

New Books in Medicine

Play Episode Listen Later May 6, 2025 67:56


While Kim Crespi was getting a haircut, her husband David murdered their five-year-old twin daughters during a game of hide and seek. In the aftermath, family, friends, and even David have more questions than answers. In 2005, Kim Crespi had what she later described as "the perfect life." She and her husband, David--a gentle giant of a man, devoutly religious, a loving father, and a proven star in the world of finance--had five healthy, happy children. No one, least of all Kim, ever suspected that the life the Crespis had lovingly woven together could be destroyed in less than forty minutes.In Medication, Mental Illness, and Murder, author Edward L. Jones III chronicles David Crespi's struggles with insomnia and depression, the role SSRI antidepressants may have played in the killings, and Kim's unimaginable journey of trauma, suffering, and eventual forgiveness as documented by her journal entries.Using letters and other forms of personal communications with David, plus excerpts from scholarly articles and more, Jones takes readers on a journey into the dark heart of psychosis, of North Carolina's penal and mental health systems, and of Big Pharma. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Make Your Damn Bed
1436 || dance as an anti-depressant

Make Your Damn Bed

Play Episode Listen Later May 2, 2025 10:04


Dance has been outperforming SSRI's, anti-depressants, and all other forms of exercise in combatting depression symptoms in multiple studies. It makes sense to me that the combination of mental + physical coordination, the way it grounds you + forces you to be present, and the social aspect would have a profound effect on our health but it makes you wonder what other cultural practices and wisdom we've overlooked. SOURCES:The Dance vs. Depression Study: https://pmc.ncbi.nlm.nih.gov/articles/PMC10813489/ Another study: https://www.bmj.com/content/384/bmj-2023-075847 Articles on the topic:INDEPENDENT: https://www.the-independent.com/life-style/dance-best-exercise-depression-b2501113.html RELIEF MENTAL HEALTH: https://reliefmh.com/blog/dance-therapy-depression-anxiety/ DANCE MAG: https://dancemagazine.com/dancing-with-depression/#gsc.tab=0 HARVARD: https://hms.harvard.edu/news-events/publications-archive/brain/dancing-Donate to Palestinian Children's Relief Fund::www.pcrf.netDonate to Mutual Aid Funds: https://www.folxhealth.com/library/mutual-aid-fundsGET AN OCCASIONAL PERSONAL EMAIL FROM ME: www.makeyourdamnbedpodcast.comTUNE IN ON INSTAGRAM FOR COOL CONTENT: www.instagram.com/mydbpodcastOR BE A REAL GEM + TUNE IN ON PATREON: www.patreon.com/MYDBpodcastOR WATCH ON YOUTUBE: www.youtube.com/juliemerica Get bonus content on PatreonSupport this show http://supporter.acast.com/make-your-damn-bed. Hosted on Acast. See acast.com/privacy for more information.

Radically Genuine Podcast
182. Manufactured Evidence-The Systematic Fraud Behind Adolescent SSRI Prescribing

Radically Genuine Podcast

Play Episode Listen Later May 1, 2025 70:20


Professor Jon Jureidini is a child psychiatrist who leads the Critical and Ethical Mental Health research group at Adelaide University in Australia. His forensic deconstruction of industry-sponsored clinical trials has exposed how pharmaceutical companies manipulate data, employ ghostwriters, and cultivate academic figureheads to create an illusion of scientific consensus around their products. Prof. Jureidini has revealed how medications prescribed to our most vulnerable populations—children and adolescents—gained approval based on studies that were fundamentally misrepresented in the scientific literature. In his groundbreaking book, 'The Illusion of Evidence-Based Medicine: Exposing the crisis of credibility in clinical research,' co-authored with Leemon McHenry, he systematically demonstrates how commercial interests have hijacked the evidence base that clinicians rely on, compromising patient care in the process. His work raises profound questions about the integrity of published research and challenges us to reconsider the foundations of modern medicine. Jureidini reveals shocking findings about the landmark 'Treatment of Adolescent Depression Study (TADS) study that's been used to justify prescribing antidepressants to teenagers—despite evidence showing a five-fold increase in suicidal events. With nearly 20% of adolescent girls now taking SSRIs, this conversation exposes the profit-driven deception that puts millions of developing brains at risk while pharmaceutical companies continue to thrive on what Jureidini calls "the illusion of evidence-based medicineChapters00:00 Introduction to the Crisis in Psychiatry02:20 The Illusion of Evidence-Based Medicine04:34 The TADS Study: A Closer Look10:47 Evaluating the TADS Study's Findings14:22 The Ethics of Informed Consent26:28 Risks and Alternatives in Treatment32:59 The Controversy of Antidepressant Prescriptions35:46 Ethical Concerns in Pharmaceutical Practices40:29 The Impact of Clinical Trials on Drug Approval47:08 Challenges in Psychiatric Research and Publication50:29 Restoring Trust in Scientific Integrity58:20 A Shift Towards Social Determinants of Mental Health RADICALLY GENUINE PODCASTDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here—-----------FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

Mad in America: Science, Psychiatry and Social Justice
Chemically Imbalanced: Joanna Moncrieff on the Making and Unmaking of the Serotonin Myth

Mad in America: Science, Psychiatry and Social Justice

Play Episode Listen Later Apr 30, 2025 49:06


Welcome to this Mad in America podcast. My name is Robert Whitaker, and I'm happy today to have the pleasure of speaking with Joanna Moncrieff. Dr. Moncrieff is a psychiatrist who works in the National Health Service in the United Kingdom. She is a Professor of Critical and Social Psychiatry at University College, London. In 1990 she co-founded the Critical Psychiatry Network, which today has about 400 psychiatrist members, about two-thirds of whom are in the United Kingdom. From my perspective, the Critical Psychiatry Network has been at the forefront of making a broad critique of the disease model of care. Without this network, I don't think that critique would be anywhere near as prominent or as sophisticated as it is today. Dr. Moncrieff is a prolific researcher and writer. Her books include De-Medicalizing Misery, The Bitterest Pills: The Troubling Story of Antipsychotic Drugs, and The Myth of the Chemical Cure. Her latest book is titled Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth. This book in many ways is a follow-up to her 2022 paper which looked at the serotonin story and concluded that there was no good evidence that a serotonergic deficiency was a primary cause of depression. It caused quite a furor within the media and in psychiatry. *** A full transcript of this interview is availabe here: https://www.madinamerica.com/2025/04/chemically-imbalanced-joanna-moncrieff-making-unmaking-serotonin-myth/  Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2025. Produced by James Moore https://www.jmaudio.org  

The Franciska Show
A Medical Talk About: Vax, Ozempic, SSRi's, Jewish Anxiety, IVF - with Dr. Sharon Stoll

The Franciska Show

Play Episode Listen Later Apr 29, 2025 63:26


Navigating Medicine and Faith: A Conversation with Dr. Sharon Stoll In this episode, Dr. Sharon Stoll discusses her background growing up in a modern Orthodox Jewish community in Philadelphia, her journey to becoming a neuroimmunologist, and her professional experiences working at Yale and now in Philadelphia. The conversation touches on her approach to patient education, especially around COVID-19 and various medications, including GLP-1 agonists like Ozempic and SSRIs for mental health. Dr. Stoll also speaks about her role in JOWMA (Jewish Orthodox Women's Medical Association) and the importance of educating her community on medical issues.    The discussion covers her views on IVF, the ethical considerations of genetic selection, and the interplay of anxiety and genetic predispositions within the Ashkenazi Jewish community. Dr. Stoll shares personal anecdotes and insights into balancing professional and personal life, making this an in-depth and enlightening conversation.   00:00 Introduction and Background 01:19 Professional Journey and Achievements  02:08 Balancing Media and Medicine 03:48 Involvement with Jowma 05:40 Views on Vaccination 14:26 Discussion on SSRIs and Ozempic 28:16 Challenges in the Frum Community  34:38 Debunking Misconceptions About Diabetes 35:07 Educational Gaps and Community Efforts 36:43 Health Education in Schools 39:06 Challenges of Motherhood and Societal Expectations 43:43 Genetic Risks and Mental Health in Ashkenazi Jews 54:38 IVF, Genetic Selection, and Ethical Dilemmas  01:02:34 Concluding Thoughts and Personal Reflections   About Our Guest: Dr. Sharon Stoll is a board-certified neurologist, neuro-immunologist. She currently serves as Director of Neurology at Stoll Medical Group in Philadelphia. For the past 8 years she worked as assistant professor, in the department of neurology at Yale School of Medicine. She completed her neurology residency training at Thomas Jefferson University Hospital in Philadelphia and her Neuroimmunology fellowship at Yale New Haven Hospital. Dr. Stoll played an active role in academic development and continuing medical education. She currently serves on several steering committees and advisory boards. She has been published in numerous peer-reviewed journals and served as Principal Investigator on several clinical trials. Dr. Stoll has received numerous awards, including Top Neurologist, 40 under 40, the Rodney Bell teaching award, and is a national multiple sclerosis society grant recipient. Dr. Stoll is also a medical editor for Medscape and Healthline and previously worked as a medical editor for ABC News. She is also a medical commentator for several national and local news outlets, including ABC, NBC, and CBS News, and has been on a variety of shows, including “The Doctors”. She is an internationally renowned speaker and patient advocate.   https://www.drsharonstoll.com https://www.instagram.com/drsharonstoll/?hl=en https://www.jowma.org  

Look Forward
RFK Jr. is a Dangerous Imbecile (Van Hollen, Autism Registry, Ukraine War) | Ep409

Look Forward

Play Episode Listen Later Apr 29, 2025 66:56


This week the guys return to discuss Senator Chris Van Hollen's trip to El Salvador that was telling in many ways about Kilmar Abrego Garcia and Trump's blatant human trafficking to CECOT, Trump just tells Putin to "stop it!" when it comes to the war in Ukraine, CEOs of big box stores tell Trump to knock off all the tariff nonsense, RFK Jr absolutely insane stances on school shootings, ailments he deems "exotic, and pushing to create an autism registry, Sarah Huckabee Sanders begs an unwilling Trump for federal support in Arkansas after 14 tornadoes hit the state, Department of Education plans to destroy people credit score for reasons, Trump administration says safety checks on milk costs too much...sorry guys, JD Vance killed the Pope, Pete Hegseth has yet another Signal screw up, and much more!Big TopicOur fucking Senator shows up for his constituentThere's another MD man who was sent to gulag erroneouslyHis example is rubbing offNews You NeedStop it guys, seriously! Just stop it!CEOs get Trump to back down on tariffs AGAIN!RFK Jr is fully out there saying really insane things about autism, SSRI drugs, and other disabilitiesAutism Registry?!!!!Governor Sarah Huckabee Sanders and Arkansas enter dreaded “Find Out” stageDefaulting on Student Loans, such much winningSafe drinking milk is basically communism, so we stopped doing that48 Hours Exec Producer quits; cites losing of independence as reasonIt's not all bad!Fast Corruption and Faster Screw-UpsPope chooses death after meeting JD Vance just onceTrump just straight up lies about where gas and food pricesRon DeSantis wife stole $10 million in medicaid moneyHegseth made a SEPARATE signal chat with friends and familyAnd he PURPOSEFULLY went around secure connectionsAnd he's having a makeup room installed in the PentagonCFPB eradicated; judge steps into stop it for nowWhat's Dumber, A Brick or A Republican?…but it might work for us!

The Growth Lab with Dr. Josh Axe
She CURED Her Auto-Immune Disease Eating This One Thing | Mikhaila Peterson

The Growth Lab with Dr. Josh Axe

Play Episode Listen Later Apr 17, 2025 63:31


Is it really possible to reverse lifelong autoimmune disease with one radical dietary change? Over 24 million Americans suffer from autoimmune conditions, and many more are told there's no cure. But what if that's not entirely true?  In this eye-opening episode, Dr. Josh Axe sits down with Mikhaila Peterson Fuller– popular health influencer, founder of the Lion Diet, and daughter of world-renowned psychologist Dr. Jordan Peterson– to explore how she put a lifetime of chronic illness, inflammation, depression, and joint replacements into remission by eating only one food.  From arthritis at age 7 to multiple joint surgeries and battling severe depression, Mikhaila's story is one of relentless suffering, radical transformation, and shocking revelations about how food affects the body and mind. Today, she shares how she used a meat-only diet to heal. In this episode, you'll discover:  How Mikhaila overcame autoimmune disease, childhood illness, and psychiatric misdiagnoses Why beef was the only food her body could tolerate– and how it changed everything How the Lion Diet works and why thousands of people are turning to it for relief from autoimmunity and inflammation.  The surprising role of SSRI withdrawal, chronic fatigue, and mismanaged infections in long-term illness The role that mold, gut health, and environmental toxins play in hidden chronic disease Which therapies, tools, and practices helped her reclaim her health beyond diet If you've struggled with symptoms that doctors can't explain, if you've tried “everything” and nothing's worked, or if you're simply curious about the cutting edge of autoimmune healing, this episode is for you. You'll walk away with real hope, fresh insight, and a deeper understanding of how the body, mind, and spirit are connected– and how to begin your healing journey today.  Tune in now and discover how one woman rewrote the rules of recovery and why her story might hold the key to yours.  #autoimmune #carnivore #draxe Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. ------  00:00 Mikhaila Peterson's Autoimmune Disease Story 07:23 The Carnivore Diet & Lion Diet 15:55 Consequences of & Conditions for Carnivore Diet 25:59 Danger of Medications 27:35 Healing Lifestyle Practices 30:10 How to Build Resilience  36:24 Mikhaila's Testimony  46:00 About Peterson Academy  50:49 Best Pieces of Advice ------  Follow Dr. Josh Axe Instagram Twitter Facebook Tik-Tok Website Follow Mikhaila Peterson Fuller Instagram Twitter Facebook YouTube ------  Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get: Holistic health news & life-hacks from a biblical world view Powerful free resources including classes, Q&As, and guides from Dr. Axe The latest episodes of The Dr. Josh Axe Show Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe  ------  Links:  Explore Peterson Academy for world-class, values-based courses taught by top professors → https://petersonacademy.com/  ------  Ads:  Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at https://beyondbloodwork.com/. 

The Adam and Dr. Drew Show
Go Find a Mirror (The Adam and Dr. Drew Show Classics)

The Adam and Dr. Drew Show

Play Episode Listen Later Apr 1, 2025 56:46


Adam and Drew open the show discussing the change in Adam's flora and fauna and how that has impacted his ability to fart with impunity anytime he wants. They also talk about a letter Adam got from one of his former employees and take listener calls on SSRI's impacting weight and the details involved in getting a vasectomy.

American Thought Leaders
Antidepressants Are Having Horrific Effects on Sexual Function: Dr. Josef Witt-Doerring

American Thought Leaders

Play Episode Listen Later Mar 26, 2025 54:01


“Fifteen or 16 percent of the population [is] now taking antidepressants … When they've gone out and asked people who actually use these medications whether they're experiencing sexual dysfunction, approximately 60 percent of people will [affirm] it.”Dr. Josef Witt-Doerring is a board certified psychiatrist, former FDA medical officer, and director of the Taper Clinic. He treats patients suffering from post-SSRI sexual dysfunction (PSSD), and protracted withdrawal—two conditions becoming more common, and in some cases permanent, in people who have stopped taking antidepressants.“SSRIs and antidepressants are really popular drugs. Some people just don't want to believe that they could potentially cause something so catastrophic,” he says. “We should only be using these medications after we've done everything else.”In this episode, we discuss how patients can safely discontinue psychiatric medications and regain control of their mental health, and why there needs to be more awareness about conditions that arise after people stop taking their drugs.“What I saw going through all of that ... as a drug safety officer ... was essentially that we really were practicing outside of what the psychiatric clinical trials and the evidence showed,” says Witt-Doerring. “Doctors have been led astray about the drugs to the point where they overestimate the benefits and minimize the harm.”Views expressed in this video are opinions of the host and the guest, and do not necessarily reflect the views of The Epoch Times.