Podcasts about urolithin a

The 3 Best Supplements for Mitochondria, Energy & Longevity in Menopause Get my free Longevity Stack Masterclass and Supplement Guide for women to learn how to build a personalised supplement stack: https://academy.angelafosterperformance.com/free-longevity-stack-masterclass In this episode, Angela explains how mitochondria produce energy, why mitochondrial function can become less efficient with age and hormonal change, and the three advanced supplements she personally uses as part of her longevity strategy: NAD precursors, urolithin A and MitoQ. You'll discover how each targets a different aspect of mitochondrial health — energy production, mitochondrial renewal and protection against oxidative stress — and why supplements work best when layered on top of the fundamentals of sleep, nutrition, exercise, cardiovascular fitness, stress management and, where appropriate, optimising hormones. KEY TAKEAWAYS Why Energy Can Change in Menopause — Declining oestrogen can influence mitochondrial biogenesis and the efficiency of cellular energy production. NAD for Cellular Energy — NAD plays a critical role in helping mitochondria convert food and oxygen into ATP, the energy currency of your cells. Urolithin A for Mitochondrial Renewal — Urolithin A supports mitophagy, the body's natural process for clearing damaged mitochondria and making room for healthier ones. MitoQ for Mitochondrial Protection — MitoQ is designed to reach the mitochondria directly and help protect them against oxidative stress generated during energy production. TIMESTAMPS AND KEY TOPICS 01:38 — Three different ways to support mitochondrial health 02:50 — Supplement #1: NAD and cellular energy production 04:10 — Supplement #2: Urolithin A and mitophagy 06:22 — Supplement #3: MitoQ and oxidative stress 08:01 — Why supplements should come after the foundations 08:16 — Angela's longevity supplement protocol and free masterclass Want to go deeper? Start here:Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it. https://biosyncing.scoreapp.com/ Reset your hormones, restore your energy, and reconnect with your body in just 21 days. https://www.highperformance-health.com  Fresh Start Sunday NewsletterYour weekly 3-minute guide to creating the healthiest, most vibrant version of you.Each Sunday, get one simple habit to boost energy, balance hormones, and enhance longevity - joined by 25,000+ women worldwide. https://angelafosterperformance.com/ The Ultimate Guide to Creatine for Women - https://academy.angelafosterperformance.com/creatine-guide️ 10 Habits that Helped me reverse my Biological Age by 25 years in Perimenopause -  https://academy.angelafosterperformance.com/10-habits-optin-pageAbout Me: Angela Foster is a corporate lawyer turned health and performance coach, keynote speaker, and creator of the BioSyncing:registered: Method. Host of the High Performance Health Podcast with 500+ episodes featuring world-leading experts in longevity, hormones, neuroscience, and female performance science. The most accomplished women have everything handled on the outside, but their hormones, energy, and nervous system are quietly paying the price.The old playbook stops working in midlife.This channel is designed to help high-performing women optimise energy, hormones, cognitive performance, and longevity using science-backed strategies built around female biology. Angela's personal mission is to help 1 million ambitious women perform better, age slower, and never have to choose between success and their health. If you want to be part of that mission, make sure you subscribe and share the channel with a woman you care about. Follow me for daily health and performance tips:Instagram: @angelasfosterFacebook: @AngelaFosterPerformance

Paul Pritchard is one of the most significant figures in British climbing. He became one of Britain's leading rock climbers and mountaineers, with major first ascents across the UK, Patagonia, Baffin Island, Yosemite, Kyrgyzstan and the Karakoram. His first ascent of the West Face of Mount Asgard in 1994 remains one of his defining achievements.He was also the first author to have won the Boardman Tasker Prize for Mountain Literature twice — for Deep Play, and later, The Totem Pole.In 1998, everything changed.While climbing Tasmania's Totem Pole, Paul was struck in the head by a falling rock, sustaining a near-fatal brain injury that left him with hemiplegia. He spent the next year in hospital and has described the decades since as his longest project: healing, adapting, and learning to live one moment at a time.And yet today, Paul says he gives thanks to the Totem Pole every morning.This is not simply a comeback story. It's a conversation about mortality, fear, acceptance, freedom, identity, and what happens when the life you expected disappears.We talk about why losing choices can sometimes make us freer, why fear doesn't need to disappear before we act, how aging changes the need to prove ourselves, and Paul's idea of the “dignity of risk.”If none of us knows how much time we have, what are we still postponing?REFERENCESPaul's excellent books:: Deep Play | The Totem Pole | The Longest Climb | The Mountain Path on his website at https://www.paulpritchard.com.au/booksPaul's Instagram: @paulpritchard

In this episode, Dr. David Jockers is joined by his longtime friend Dr. Josh Axe, co-founder and chief visionary officer of Ancient Nutrition, founder of draxe.com, and founder of The Health Institute, for a deep dive into cellular longevity.   You will learn why some organs age faster than others, what's really happening inside your cell membranes and mitochondria as you get older, and which foods, from super berries and pomegranates to organ meats, healthy fats, fermented foods, and longevity mushrooms, do the most to slow that process down.   Dr. Axe and Dr. Jockers also break down his top longevity supplements, including vitamin D, soil-based probiotics, omega-3s, magnesium, and NAD/NMN, why quality matters so much more than quantity when it comes to supplements, and the surprising role of the gut microbiome, bee products, and daily herbal tea in living a longer, more vibrant life.   In This Episode:  00:00 Berry Powders Routine 00:14 Longevity Podcast Intro 04:02 What Is Cellular Longevity 04:52 Aging Organs and Cells 06:52 Cell Membranes and Mitochondria 09:26 Foods to Live Past 100 09:53 Super Berries for Longevity 13:18 Pomegranate and Urolithin A 17:24 Akkermansia and Ellagic Acid 19:00 Vegetables for Detox and Heart 20:35 Organ Meats and Methylation 23:44 Protein and Like Supports Like 25:37 Omega 3s and Healthy Fats 28:59 Oil Quality Over Smoke Point 29:18 Choosing High Polyphenol Olive Oil 30:19 Healthy Fats For Longevity 30:52 Fermented Foods And Gut Health 32:30 Longevity Mushrooms Explained 33:58 Longevity Foods Recap 34:42 Top Supplements Vitamin D 40:13 Probiotics Omega 3 And Quality 43:32 Avoiding Bad Supplements Calcium 44:21 NAD NMN And Supplement Impact 46:54 Magnesium Adaptogens And Green Tea 48:44 Bee Products And Venom Therapy 51:23 Herbal Tea Daily Ritual 52:28 Where To Find Dr Josh Axe 53:50 Final Thanks And Sign Off   This podcast is sponsored by Paleo Valley's Turmeric Complex, a whole-food organic turmeric formula (not just isolated curcumin) blended with coconut oil and black pepper for absorption, plus ginger, rosemary, and cloves for extra anti-inflammatory and brain-support benefits. Go to paleovalley.com/jockers for 15% off your order.   Bon Charge's Red Light Toothbrush combines the most researched red and near-infrared wavelengths (660 and 830 nanometers) with sonic power to support circulation, manage gingival inflammation, and aid recovery after dental procedures, all in your everyday brushing routine. It's HSA/FSA eligible, travel-ready, and low EMF. Go to boncharge.com and use code DRJOCKERS for 15% off, with free shipping and a 12-month warranty.   Inflammaging, the chronic low-grade inflammation that accelerates aging, often shows up first in the skin. Holistic Goddess Frankincense Castor Oil roll-on uses organic, cold-pressed, hexane-free castor oil and organic frankincense to deeply moisturize and soften the look of fine lines, with a cooling rose quartz applicator. Go to holisticgoddess.com and use code DRJOCKERS for free shipping.   Busy, stressed, low-carb, or training hard? You're likely losing more electrolytes than you realize. ReLyte from Redmond is made with Redmond's Real Salt, an ancient, unrefined Utah sea salt with trace minerals, plus two types of magnesium for better absorption, no sugar, and no artificial ingredients. Go to redmond.life/doctorjockers and use code JOCKERS for 15% off. "Pomegranates are right up there with goji berries as top superfoods for longevity."   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources:  Visit paleovalley.com/jockers to get 15% off Paleo Valley's Turmeric Complex and other products Visit boncharge.com and use code DRJOCKERS for 15% off the Red Light Toothbrush, with free shipping and a 12-month warranty Visit holisticgoddess.com and use code DRJOCKERS for free shipping on the Frankincense Castor Oil roll-on Visit redmond.life/doctorjockers and use code JOCKERS for 15% off ReLyte electrolytes     Connect with Dr. Josh Axe: Website – https://draxe.com/ Instagram – https://www.instagram.com/drjoshaxe/ Book – https://amzn.to/4glff4y   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

Full show notes: https://bengreenfieldlife.com/holyhealth In this episode with Justin Roethlingshoefer, you'll hear from a former NHL performance coach turned health entrepreneur whose new book, Holy Health, is the one I chose for my father-son book club this month. This is not another eat-honey-and-drink-milk Bible health book. Justin is a genuine biohacker who works with pro athletes worldwide, and he has woven deep spiritual and physiological science into the same framework. You'll learn why the modern obsession with optimization can quietly become idolatry, how the drive to control your metrics keeps your nervous system stuck in fight-or-flight and lowers your HRV, and the five "hearts" that trap high performers in striving. You'll also get the practical side: his full morning and evening rhythms, why he starts his day at 6 p.m. rather than at sunrise, the breathwork he does midday in the grass, his exact zone two and zone five weekly targets, and how he folds three and a half hours of zone two into family walks with a weighted vest. It's a conversation about doing less frantic optimizing and more intentional stewardship, and it may reframe how you think about every biohack you own. Episode Sponsors: Tiny Health: An at-home microbiome test that uses metagenomic sequencing to analyze your full gut ecosystem and give personalized, evidence-based diet, lifestyle, and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN. Timeline: Give your cells new life with Mitopure, which unlocks a precise dose of the rare Urolithin A molecule to promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. JOYMODE: Spice things up in the bedroom and boost your sexual performance naturally, without prescription drugs. Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order. Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off. BIOptimizers Magnesium Breakthrough: Seven essential forms of magnesium in one full-spectrum serving to help you relax, unwind, and sleep deeply so you wake up refreshed. Go to bioptimizers.com/ben and use code ben15 for 15% off any order.See omnystudio.com/listener for privacy information.

We spend a lot of time preparing our bodies for the next 30 or 40 years.Strength. Mobility. Sleep. Recovery. Longevity.But almost nobody prepares for how sex, desire, intimacy, and pleasure may change over that same stretch of time.In this conversation, I speak with Joan Price, one of the best-known voices on sex and aging, about what changes, what can actually get better, and what we should understand long before we think we need to.Joan is 82, but much of what she shares may be most useful in your thirties, forties, and fifties.We talk about physical changes, why exercise matters, how desire evolves, why communication becomes more important, and how intimacy can adapt as we age.This is a conversation about the next 40 years of your body — and a part of longevity we rarely prepare for.Note: This episode includes frank discussion of sex, sexual function, grief, and intimacy.Joan's Books & ResourcesJoan's books include Naked at Our Age, Sex After Grief, The Ultimate Guide to Sex After 50, Better Than I Ever Expected, and Ageless Erotica.Learn more about Joan's books, webinars, newsletter, and other resources at JoanPrice.com. If you'd like to buy one of her books, consider purchasing through her website: joanprice.com/books 

If you're training hard, eating well, and still watching your waist thicken, I want you to hear this: you are not lazy, and your metabolism is not broken. Something else is going on, and once you see it, belly fat stops feeling like a mystery you can't crack. So I called in four people I trust most on this, Ben Azadi, Dr Sarah Berry, Cynthia Thurlow, and Mary Claire Haver. Together we get into why cortisol parks fat right around your middle, how losing estrogen quietly reroutes fat from your hips to your belly, and why the exact same meal spikes your blood sugar far more after menopause than it did before. We go deep on the pieces most women never get told about, the muscle you're losing, the gut and estrobolome shifts, and the insulin exposure that makes this fat feel so stubborn. Then I hand you the fix. My five levers, in the order that actually works, from breaking up long sitting to resistance training, smart HIIT, whole-food carbs, and protecting your sleep and stress. And I tell you honestly where fasted training helps and where it just becomes another way to punish yourself. If you're a busy woman over 40 who's done with "eat less, move more" and wants to know which lever your body needs first, this one's for you. WHAT YOU WILL LEARN - Does cortisol cause belly fat in women over 40? - Why does fat move to your belly during menopause? - Is menopause belly fat caused by a slow metabolism? - What is visceral fat and why is it dangerous? - Can you gain visceral fat even if the scale doesn't move? - Why do post-menopausal women have higher blood sugar spikes? - How does insulin resistance drive stubborn belly fat? - Does the gut microbiome affect body composition in midlife? - How does breaking up sitting improve insulin sensitivity? - Does resistance training help you lose belly fat after 40? - Does HIIT reduce abdominal fat in women? - Does fasted training help burn visceral fat? TIMESTAMPS - 00:00 Why Cortisol Drives Stubborn Belly Fat In Women Over 35 - 03:00 Insulin Resistance, Estrogen Loss And Why Menopause Moves Fat To Your Belly - 09:44 How Muscle Loss And Your Gut Control Midlife Body Composition - 16:11 Why Menopause Belly Fat Is Dangerous And How To Shift Visceral Fat - 17:59 The 5 Levers To Lose Midlife Belly Fat Without A Broken MetabolismVALUABLE RESOURCES Timeline - Support your mitochondrial health: Timeline Mitopure delivers Urolithin A at the clinically studied dose to support cellular renewal and energy production, helping counter the natural decline in mitochondrial function that comes with age.

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Emily Werner, PhD, RD, CSSD, IFNCP is Team Dietitian for the Philadelphia 76ers (NBA) and Philadelphia Flyers (NHL), and Nutrition Affairs Sport Lead at Timeline. Dr. Emily joins Dr. Mike to unpack postbiotics, urolithin A, and why mitochondrial health matters for pro athletes and everyday people alike, digging into the real research behind Timeline's Mitopure and why chasing $200K gadgets rarely beats getting the fundamentals right. Expect to learn what a postbiotic actually is and how urolithin A differs from other supplements, why old-school and new-school sports dietitians disagree on peptides and supplement fads, how chronic undereating quietly undermines performance in women's sports, what the current human performance research on urolithin A actually shows, how Mitopure is dosed and why urolithin A can't be reliably food-sourced, and why product quality and manufacturing integrity matter more than marketing claims, and much more. Connect with Emily: Website: https://www.eateliteperform.com/ Instagram: @emilywerner34 LinkedIn: https://www.linkedin.com/in/emily-n-werner-phd-rd-cssd-ifncp-4a820a97/ Episodes you'll enjoy next: #377 — Methylene Blue for Mitochondria & Performance: Benefits, Dosing & Risks with Dr. Scott Sherr: Listen here #382 — Creatine for Muscle, Bone, Brain & Longevity (Plus Caffeine, Dosing, and Safety) with Dr. Darren Candow: Listen here Episode Timestamps: 2:21 Welcome & introductions 6:09 What is a postbiotic? Pre-, pro-, and postbiotics explained 7:09 Urolithin A: the postbiotic behind Mitopure 8:19 How Emily started consulting for Timeline 10:11 Old-school vs. new-school sports dietitians on supplements 13:53 Peptides, anecdata, and why athletes ignore the data 20:05 The hardest lesson: letting go when clients won't listen 21:15 Money, ego, and athletes chasing $200K wellness gadgets 24:53 Chronic undereating in women's sports 30:48 Nutrition's real job: keeping athletes available to play 33:19 Inside Mitopure: Timeline's flagship urolithin A product 35:06 Mitochondria, mitophagy, and why they matter as we age 38:16 Diet, fasting, and exercise as natural mitophagy triggers 43:36 What the performance research on urolithin A actually shows 53:19 Aging, aerobic capacity, and Emily's 101-year-old grandma 55:40 Mitopure dosing: how much urolithin A and when to take it 57:14 Why urolithin A can't be food-sourced (and can't be faked) 1:03:19 Why product quality and integrity matter in supplements Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter

Full show notes: https://bengreenfieldlife.com/peptides2026 In this episode with Dr. Matt Cook, recorded days after he returned from Washington, D.C., you'll get a breakdown of what just happened to peptides in the United States. You'll hear what the FDA's Pharmacy Compounding Advisory Committee actually voted on, why seven popular peptides were pulled two years ago, which six of the seven were just recommended for the bulk list, which one was left off, and what all of it means for your ability to get peptides legally from a pharmacy instead of the gray market. You'll also get a guided tour of the peptides themselves: BPC-157 for gut and tissue healing, KPV for inflammation, TB-500 for cell migration and wound repair, MOTS-c as an exercise mimetic, Semax for memory and learning, Epitalon for sleep and longevity, and DSIP for sleep. Dr. Cook explains why peptides behave so differently from ordinary drugs, walks through a safety review covering millions of doses, and shows how his company LifeOS pulls your labs, wearables, and genetics into one HIPAA-compliant place. And if you want to keep every peptide straight, Dr. Cook built a peptide cheat sheet covering what each one does, how to dose it, and where to source it. Episode Sponsors: Timeline: Give your cells new life with high-performance products powered by Mitopure, which unlocks a precise dose of the rare Urolithin A molecule to promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. Xtendlife Prosta Support Advanced: Comprehensive daily prostate support combining clinically studied ingredients like saw palmetto and beta-sitosterol with vitamins, minerals, and botanicals. Visit Xtendlife.com/BensChoice and use code GREENFIELD for 15% off. Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/BEN with code BEN. BIOptimizers Magnesium Breakthrough: Seven essential forms of magnesium in one full-spectrum serving to help you relax, unwind, and sleep deeply so you wake up refreshed. Go to bioptimizers.com/ben and use code ben15 for 15% off any order. ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off.See omnystudio.com/listener for privacy information.

Dr. Ted Lain and Dr. Patti Farris cut through the hype around today's most popular longevity supplements.They dig into the real (and often surprisingly thin) clinical evidence behind NAD precursors like NMN and nicotinamide riboside, the gut-derived compound Urolithin A, creatine for brain and muscle health, multivitamins and the buzzy Cosmos trial, and off-label rapamycin use.Along the way, they talk through epigenetic clocks, precision medicine, why mouse studies don't always translate to humans, and why "TBD" might be the most honest verdict on longevity science right now.Plus, details on their upcoming Science of Skin Longevity Summit, February 19–21, 2027, in Scottsdale, Arizona.Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.

This week's supplement spotlight—spermidine; American Heart Association does a 180° on coffee; How accurate are health tracker wearables for sleep, blood pressure, heart rate? A skin disorder practically no one has heard of is often confused for skin cancer; Vitamin D—what forms and what dosages are optimal? Popular sugar substitutes may be worse for the brain than natural sugar.

Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.  

Metabolic flexibility expert Ben Azadi joins me to explain why cortisol, not diet alone, drives stubborn belly fat in midlife women. WHAT YOU'LL LEARN Why cortisol, not just diet, is the real driver of stubborn belly and visceral fat in women over 35 What role carbohydrates actually play in lowering cortisol load and supporting recovery Why the three hours before bed matter more for fat loss than your workout window How to time fasted workouts around your menstrual cycle for the best hormonal response Why sleep, steps and sunlight need to come before any diet or fasting protocol How increasing protein and building muscle mass changes your insulin sensitivity What's really causing your bloating, and why it may have nothing to do with your gut TIMESTAMPS 00:00 Metabolic Flexibility, Cortisol Belly Fat And The Overnight Fat-Burning Sleep Window 10:08 Fasted Training By Menstrual Cycle, Sleep Foundations And Building Muscle For Insulin Sensitivity 20:55 Why Stress Causes Bloating Plus Ben's Top Biohacks: Sauna, Red Light Therapy And Lymphatic Flow 27:00 Ben Azadi's Ketoflex Revised Book And Where To Connect With Him VALUABLE RESOURCES Ketoflex Revised (Ben's new book)  https://ketoflexbook.com/ Ben Azadi's website https://benazadi.com/ Follow Ben on Instagram https://www.instagram.com/thebenazadi/ Timeline - Support your mitochondrial health: Timeline Mitopure delivers Urolithin A at the clinically studied dose to support cellular renewal and energy production, helping counter the natural decline in mitochondrial function that comes with age.

Full show notes: https://bengreenfieldlife.com/lotus In this episode with KJ Dhaliwal of Lotus AI, you'll hear how translating his immigrant parents' doctor visits as a child and years spent bouncing through fragmented specialty care as a teenager after a disc herniation shaped his mission to give 100 million Americans free, world-class primary care using AI. KJ breaks down how Lotus AI pulls your entire medical history from every clinic and hospital you've ever visited in minutes, unifies it with your wearables and genetic data, and makes it available to both a conversational AI and a network of real licensed physicians who can diagnose you, prescribe treatment, and refer you to a specialist in under two minutes at any hour of the day. We also touch on why hospitals are quietly selling your health data to pharma, how the business model works when the product is free, and why KJ believes the AI-powered general doctor is not just possible but already happening. KJ Dhaliwal is the founder and CEO of Lotus AI. Before Lotus, he co-founded the largest South Asian dating app, which he grew and sold. At Lotus AI, his mission is to collapse the cost of healthcare delivery while making world-class primary care free and permanently accessible to every American. Download the Lotus AI app here. If you are a physician, visit lotus.ai and sign up for Lotus Cortex. Episode Sponsors: Anthros: You can train hard and still undo a lot of that progress by sitting for the next eight hours, which is why Anthros takes a different approach, starting with a Precision Posture System at the pelvis so your spine naturally aligns, plus a built-in Clinical Posture Consult that helps identify issues you may not even realize you have. Go to anthros.com and use code BEN for an exclusive $200 discount and try it risk-free for 60 days. Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Dr. Murray Natural Products – ThymoQuin®: ThymoQuin® is a clinically researched black seed oil formulated to support healthy cortisol levels, improve resilience to everyday stress, and promote overall well-being. It's the only black seed oil that meets U.S. Pharmacopeia guidelines and is backed by human clinical research. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. Qualia Stem Cell: Qualia Stem Cell is a science-backed supplement designed to support your body’s natural repair system by enhancing stem cell function, helping you recover, renew, and maintain healthy tissues as you age. Taken just four days per month and formulated with premium, clinically supported ingredients, it’s an easy way to support long-term healing and vitality. Visit qualialife.com/boundless and use code BOUNDLESS for 15% off.See omnystudio.com/listener for privacy information.

Carnitine, with acknowledged muscle and brain benefits, may find a new role in supporting cancer immunity; Calcium and vitamin D's bone-building impact may be limited; Internal visceral fat may accelerate brain aging, MRI study finds; The remarkable benefits of a newly-discovered mitochondrial booster—urolithin A (Mitopure®️).

Dealing with the heat - Europeans' disdain for air conditioningI have scaly and bumpy areas on my scalp that itch!Did homeopathic human growth hormone increase my cholesterol?

Try Danger Creatine: https://dangercoffee.com/products/danger-creatineTry TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.Thank you to our sponsors!ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – The Longevity Switch0:47 – Why Mitochondria Matter2:28 – What Mitophagy Is2:46 – How Mitophagy Works4:18 – What Shuts It Off8:54 – The Damage Compounds9:22 – How to Turn It Back On10:31 – Signal 1: Fasting11:48 – Signal 2: Exercise (REHIT)12:30 – Signal 3: Cold Exposure13:22 – Signal 4: NAD+14:29 – Signal 5: Urolithin A and SpermidineConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you've been told that menopause means muscle loss, weight gain, and declining strength are inevitable, the science says otherwise. In this episode, world-renowned strength scientist Dr. Eric Helms explains what actually drives body composition changes during perimenopause and menopause and why progressive strength training, good sleep, and consistent nutrition matter far more than chasing the latest social media trends. WHAT YOU'LL LEARN Why sleep disruption during perimenopause may be the biggest hidden driver of fat gain, poor recovery, and stalled progress Why progressive overload not lifting the heaviest weights possible is the key to building muscle and protecting bone health Whether women really need to train with heavy 5x5 programs or if moderate weights and higher reps work just as well How many sets, reps, and weekly training sessions are actually needed to build muscle after 40 Why muscle building should take priority over endless fat-loss cycles if you want to improve your shape and body composition The biggest myths about training timing, fasted workouts, cortisol, and "optimal" exercise routines How much cardio you really need for longevity, metabolic health, and body composition Whether women can build significant muscle in their 40s, 50s, and beyond even if they've never lifted weights before What the evidence actually says about menopause hormone therapy (HRT), testosterone therapy, muscle growth, and body composition How much protein you really need for muscle growth, fat loss, and healthy ageing and why total daily intake matters more than perfect meal timing Whether collagen supplements truly improve connective tissue and skin health according to the latest research TIMESTAMPS 00:00 Why body composition changes during perimenopause00:31 What's really happening physiologically during menopause01:10 Why sleep becomes the biggest factor affecting results03:25 How poor sleep impacts muscle gain and fat loss06:20 Bloating, water retention, and hormonal changes explained08:55 The biggest mistakes women make during menopause11:20 Why resistance training is the most important intervention16:50 Do women really need to lift heavy?22:30 How to build muscle and improve body shape after 4026:30 The ideal rep ranges, training intensity, and volume30:57 How much training is actually enough?37:56 Cardio for longevity, health, and body composition42:53 Can women still achieve incredible results in their 40s and 50s?49:00 The truth about hormone replacement therapy and testosterone54:35 Protein recommendations explained01:06:00 Does collagen actually work?01:09:18 Final takeaways A BIG thank you to our sponsors who make the show possible:

Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline's branded supplement Mitopure. She describes urolithin A's discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.

CBD may slow Alzheimer's progression by tamping down brain inflammation; Fifty million dollar settlement in Gardasil Classic action; Urethral stricture as a side effect of ablation for enlarged prostate; Zero-sugar diet may have unanticipated adverse health consequences; Are there drug-free alternatives for atrial fibrillation? Can you reverse lactose intolerance with a skin patch?

You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it's NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't complicated, but the order you do it in matters. In this video, Dave breaks down what this molecule is, why your body is actively working against it, and the exact protocol (diet, fasting, exercise, and supplementation) to restore it before the gap gets any wider.Thank you to our sponsors!Gatlan | Book your free consultation at www.gatlan.com/DAVEViome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – The Longevity Switch0:47 – Why Mitochondria Matter2:28 – What Mitophagy Is2:46 – How Mitophagy Works4:18 – What Shuts It Off8:54 – The Damage Compounds9:22 – How to Turn It Back On10:31 – Signal 1: Fasting11:48 – Signal 2: Exercise (REHIT)12:30 – Signal 3: Cold Exposure13:22 – Signal 4: NAD+14:29 – Signal 5: Urolithin A and SpermidineConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Full show notes: https://bengreenfieldlife.com/bretthurt In this episode with Brett Hurt, serial tech entrepreneur and author of Love Conquers Fear, you'll hear how he went from coding obsessively at seven to building one of the early internet's most popular games, surviving the dot-com bust, orchestrating two major exits, data.world to ServiceNow and Bazaarvoice's billion-dollar IPO, and experiencing a psychedelic awakening at 50 that redirected his entire life. You will also hear his vision for what an Age of Abundance looks like in practice, from solar energy and robotics to brain-computer interfaces and the role AI might play in solving problems like clean water, food security, and healthcare access in places like Chad, and why Brett believes the single most important variable in whether AI helps or hurts humanity is whether the people building it are operating from love or from fear. Brett Hurt is a tech entrepreneur and investor. He co-founded and led data.world, acquired by ServiceNow in July 2025, and previously co-founded Bazaarvoice and Coremetrics, acquired by IBM. Through his Love Conquers Fear holding company and podcast, he explores how AI and emerging technologies can either amplify fear or help create broad-based human flourishing. Pick up a copy of Love Conquers Fear to discover how Brett crosses the streams of ancient wisdom and cutting-edge technology, rewiring humanity's relationship with AI, quantum computing, and emerging tech to move us from scarcity to abundance. Episode Sponsors: ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol. Order with a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. JOYMODE: Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order. Quantum Upgrade: Recent research revealed Quantum Upgrade increased ATP production by 20-25% in human cells. Unlock a 15-day free trial with code BEN15 at quantumupgrade.io. Timeline: High-performance products powered by Mitopure, delivering a precise dose of the rare Urolithin A molecule for healthy aging. Mitopure starts at $79 at timeline.com/BEN.See omnystudio.com/listener for privacy information.

I'm 78 and had a hysterectomy.  Is it safe for me to eat tofu or other soy foods?Mitopure joins L'Oreal to create a face cream with Urolithin A.Does taking hyaluronic acid orally cause water retention?Can you discuss ETA contained in New Zealand green mussels?What are your thoughts on using vibration devices to help osteoporosis?

Why aren't there more medical insurance plans that cover alternative medicine? Solutions for Long Covid; MK7 vitamin K slows arterial calcification; Keto diet shows promise for treatment of anorexia; It's not so much salt restriction—it's the dietary sodium/potassium ratio in hypertension; Study finds multivitamins don't keep you from getting Covid—but when you get it, it's milder; Incidence of social anxiety disorder is soaring among young people.

Should you stop taking glucosamine based on a new study linking it to Alzheimer's? What's behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.

ISSN Conference Rundown: Lactotripeptides, GLP-1 Support, Astaxanthin, Beta-Alanine, Urolithin A, and Wearables In this Iron Radio episode, hosts Coach Phil Stevens, Dr. Mike T. Nelson, and Dr. Lonnie Lowery recap highlights from the ISSN conference. They discuss sponsored research on casein lactotripeptides and their possible effects on blood flow, “pump,” and hypertrophy; a presentation on nutrition support for GLP-1 users and high dropout rates; and updates on astaxanthin as a carotenoid antioxidant with emerging dosing and metabolism data. They review a beta-alanine tutorial covering loading timelines, paresthesia, and dosing, and talk with Emily Werner about urolithin A, mixed evidence, cost, and sourcing concerns. Other topics include amino acids for tendon recovery, communication of sports nutrition in media, a practical sports nutrition lecture emphasizing field validity and “don't assume—go look,” MSM for recovery, EAAs and cognition, and Mike's wearable tech takeaways, including poor calorie-burn estimates and HRV/respiratory rate considerations. 00:00 Welcome and Hosts 01:42 Conference Recap Setup 02:14 Milk Peptides and Pump 08:27 GLP-1 Nutrition Support 10:31 Astaxanthin Deep Dive 14:19 Beta Alanine Update 21:05 Urolithin A Buzz 22:04 Urolithin A Evidence 23:31 Personal Trials and Cost 25:12 Buying Legit Sources 27:14 Amino Acids for Tendons 29:02 Media Nutrition Messaging 31:01 Real World Sports Nutrition 34:11 MSM and Immune Stress 36:20 EAAs for Cognition 39:09 Wearables Accuracy Reality 43:42 Conference Wrap and Farewell Donate to the show via PayPal HERE.You can also join Dr Mike's Insider Newsletter for more info on how to add muscle, improve your performance and body comp - all without destroying your health, go to www.ironradiodrmike.com Thank you!Phil, Jerrell, Mike T, and Lonnie

Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/If you're eating clean, taking the right supplements, and still feel exhausted and mentally foggy - the problem isn't your protocol. Your body has a built-in cellular cleanup system that determines whether any of those inputs actually work, and right now it's almost certainly switched off. In this video, I break down what that system is, how chronic stress and all-day eating suppress it without you ever feeling it, and the specific compounds that flip the longevity switch back on through independent biological pathways that nothing else touches.Thank you to our sponsors!ECHO Water | Go to http://echowater.com/daveand use code DAVE10 for 10% off your ECHO Flask.EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – The Longevity Switch0:47 – Why Mitochondria Matter2:28 – What Mitophagy Is2:46 – How Mitophagy Works4:18 – What Shuts It Off8:54 – The Damage Compounds9:22 – How to Turn It Back On10:31 – Signal 1: Fasting11:48 – Signal 2: Exercise (REHIT)12:30 – Signal 3: Cold Exposure13:22 – Signal 4: NAD+14:29 – Signal 5: Urolithin A and SpermidineConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Resistance training is one of the most powerful interventions for preserving muscle, supporting metabolic health, and promoting healthy aging—but many patients still find it intimidating or confusing. In this episode, Dr. Kara Fitzgerald sits down with exercise physiologist Brad Currier, PhD, to unpack the newly updated ACSM resistance training guidelines and discuss practical approaches for prescribing exercise across the spectrum, from sedentary adults to elite athletes. In partnership with Timeline, they also review the latest clinical research on Urolithin A, mitochondrial function, muscle recovery, protein, and creatine, offering actionable insights for functional medicine practitioners. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Dr. Brad Currier is Manager of Clinical Trials at Timeline, a Swiss biotech company at the forefront of longevity science for over 15 years. With a background in elite athletics, he went on to earn a PhD in muscle physiology, where his research focused on how exercise and nutrition influence aging and performance. Brad has led numerous clinical trials conducted around the world and published extensively in peer-reviewed journals. He is also the lead author of the American College of Sports Medicine's new position stand on resistance training prescription, helping shape global guidelines for strength training and healthy aging. THANKS TO OUR SPONSOR TIMELINE: http://Pro.timeline.com At the core of Timeline is Mitopure®, a pure and patented form of Urolithin A, shown to improve mitochondrial dysfunction. Learn more & Sign up for a Healthcare Practitioner account at http://Pro.timeline.com Email: care@timeline.com CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach? 

Why Wearing Sunscreen All Day May Be Doing More Harm Than Good for Women Over 40 In this thought-provoking episode, Angela Foster sits down with renowned beauty expert and author Liz Earle MBE to challenge conventional wisdom about sunscreen and sun exposure. Liz discusses why current public health messaging around universal, all-day SPF use might be too extreme, potentially robbing us of vital Vitamin D and other essential benefits of natural daylight. KEY TAKEAWAYS Many people assume they still get Vitamin D while wearing sunscreen. However, Liz points out that this only happens because most people apply it too thinly or miss spots.  Applying high SPF when it is completely unnecessary, like on a dark winter morning during an underground commute, is a sign that public health messaging has become too broad.  Our skin isn't just a physical barrier; it actively receives light and communicates with the body's immune system.  Exposing your skin to gentle, early-morning sunlight (when the UV index is low) acclimatizes it.  Medical professionals and researchers are beginning to speak out against extreme sun avoidance.  BEST MOMENTS "When people say, 'Yes, you get Vitamin D from the sun when you're using sunscreen,' yeah, because you're not using your sunscreen properly. You're actually allowing some of that UVB to come through the skin." "The worst thing that we can do is stay indoors all year and then rush out for our two-week summer beach holiday and fry ourselves on the beach... That's because our skin has not got used to the sunlight." "The skin is actually an organ of light reception. This is what we're just beginning to understand, that the skin has light receptors on it for reasons—they're signaling, it's not just blocking and keeping our insides intact." "I don't know if you take collagen supplements, I do, but actually by going out in early morning light, I'm telling my body to make more collagen. So it's preparing the skin." "He says that he thinks that we will look back at this time and our lack of sun exposure as being as damaging to our health as smoking." VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

Ben Hartman is back for his third visit to the PricePlow Podcast in Episode #221, and Morphogen Nutrition has never been in a stronger position. Ben walks through everything: the second rebrand’s full backstory, a never-before-told story about a failed acquisition that nearly sold the company, the financial reckoning that followed, and how selling the building and moving to a 3PL model finally cleared the slate. He calls this the best formula work Morphogen has ever done, at the healthiest margins in company history. The conversation covers AlphaGEN’s return to 10g L-Tyrosine, why PRIME is the anchor of the entire health line, details like how he navigates AstraGin® and BioPerine® across a multi-product stack, and the surprising origin of CALM. Then comes the main event: the Nick Walker equity partnership, explained in full, including some of the financial structure the internet has been speculating about. The episode closes with a frank look at the longevity wave ahead, the natural-vs.-enhanced debate, and a nostalgic look back at the golden age of stimulants. Subscribe to the PricePlow Podcast on your favorite platform and sign up for Morphogen Nutrition news alerts before diving in. https://blog.priceplow.com/podcast/ben-hartman-morphogen-nutrition-221 Video: Morphogen’s Second Rebrand, Nick Walker Equity, and the 10g Tyrosine Return https://www.youtube.com/watch?v=1avyjD3spOk Detailed Show Notes: Ben Hartman on Morphogen’s Rebrand, the Nick Walker Deal, and Where Supplements Are Heading (0:00) – Introductions (0:45) – The Second Rebrand: What Triggered It (3:00) – The Failed Acquisition: First Public Account (5:00) – David DeMesquita: The Missing Third Partner (8:45) – Business Lessons: Termites at the Foundation (12:30) – Best Formulas Ever, Healthiest Margins Ever (13:15) – Hero vs. Backup Ingredients: Supply Chain and Formula Thinking (18:30) – Diminishing Returns: “Racing to the Bottom” (20:30) – Breaking the Debt Cycle: PO Discipline and the Move to 3PL (27:45) – ALPHAGEN Reborn: The 10g L-Tyrosine Decision (30:15) – Eria Jarensis, Manufacturing Partners, and Label Honesty (35:15) – PRIME: Origin Story and the Anchor Health Product (40:30) – AstraGin® and BioPerine®: Choosing Absorption Enhancers Wisely (46:30) – CALM: From Bodybuilding Contest Prep to Gen Pop (51:15) – “I Don’t Listen to My Customers” (54:45) – Blood Work, Hormones, and Realistic Self-Assessment (1:01:30) – The Nick Walker Partnership: How It Actually Happened (1:04:30) – Equity, Not a Paycheck: “We Gave It to Him” (1:11:30) – Nick’s Feedback, Carb Fuel, and PROTEGEN on the Way (1:16:45) – From Bodybuilding Brand to Health and Wellness (1:21:30) – The Longevity Wave: NMN, Urolithin A, and Mitochondrial Health (1:27:00) – Natural vs. Enhanced: An Honest Reassessment (1:35:00) – The Supplements That Actually Moved the Needle (1:38:00) – Stimulant Nostalgia: DMAA, Ephedrine, and What’s Still Available (1:40:45) – Dedra Hartman (CFO) and Closing Thoughts Where to Follow and Learn … Read more on the PricePlow Blog

Most women in perimenopause are training hard, eating well, and still dealing with joint pain, stiffness, and injuries that never fully heal. Juliet Starrett, New York Times bestselling author and co-founder of The Ready State, joins me to reveal why the joint pain and stiffness so many women write off as ageing is actually a specific syndrome nobody warned you about. We get into what 30 minutes of floor sitting a day can do for your hips and low back, why most exercise routines are silently narrowing your range of motion, and the five weekly movement non-negotiables Juliet recommends for every woman over 40. WHAT YOU'LL LEARN • Why perimenopause triggers joint pain, frozen shoulder, and mobility loss • How 30 minutes of floor sitting a day rewires your hips and reduces pain• Best movement habits for women over 40 • How strength training may be stealing your flexibility over time • How to train through injury without making it worse • The HRV myth debunked and what to track instead VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body and how to fix it.

Whittling your diet down to five "safe" foods isn't healing your gut — it's masking a deeper imbalance that declining estrogen may be driving. Nutrition expert Cynthia Thurlow joins Angela Foster to unpack why so many women suddenly can't tolerate foods they once ate freely, and what's really happening behind the bloating, palpitations and brain fog. The conversation explores the link between estrogen loss and a leaky small intestine, the histamine-hormone "perfect storm" that can trigger hives and cramping, and why bloating during perimenopause is so often multifactorial. Cynthia also explains when bloating becomes a red flag worth investigating. You'll learn how to identify your personal food triggers without cutting entire food groups, why eating in a parasympathetic state matters, and which gut supports — from fibre and hydration to TUDCA — can help as progesterone and estrogen decline. If you've ever felt like your body suddenly turned against your favourite foods, this episode will help you understand why. KEY TAKEAWAYS Stop eliminating food groups as your default fix. Whittling your diet down to a handful of "safe" foods signals an underlying gut imbalance that needs support — not an ever-expanding exclusion list. Recognise food sensitivities as a likely leaky gut symptom. As estrogen declines it acts like failing "mortar" in the small intestinal lining, letting food particles leak into the bloodstream and provoke an immune response. Watch the histamine-estrogen "perfect storm." During high-estrogen days, loading up on high-histamine foods (leftovers, kombucha, fermented items) can trigger hives, congestion, cramping and diarrhoea — so keep histamine foods low or infrequent during those windows. Eat in a parasympathetic state. Sit at a table, remove distractions, and take four to five deep breaths before meals rather than eating standing, in the car, or on the move. Always get persistent bloating evaluated. Bloating from morning to night is different from bloating that appears after meals, and persistent symptoms should be checked because, in rare cases, they can signal something serious like ovarian cancer. QUOTES "The goal is to never get to a point where you're excluding entire classes of foods." "If we look at the small intestinal lining as like a brick and mortar system, the mortar is the estrogen." "I literally was talking to a podcast host and I broke out in hives head to toe because I was high estrogen, high histamine stress. And it was like the perfect storm." "It's not really that you need to cut out all these food groups. We just have a nuanced conversation. Don't go overboard with any one food." "I've just seen too many people blow off symptoms for a year or two that end up being bigger issues than they would have been had they been addressed up front." VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast, Mikki speaks to Brad Currier, Science Lead at Timeline Nutrition and lead author of the recent American College of Sports Medicine position stand on resistance training.In this episode, the conversation begins with Urolithin A and Mitopure, exploring what it is, what it does in the body, and why it has become an area of interest for mitochondrial health and muscle function. Brad explains the proposed mechanisms, the current human evidence, and what outcomes have actually been shown to improve, from cellular-level changes through to potential real-world benefits.Mikki and Brad also discuss who may be the best fit for a supplement like this, including older adults, athletes, and those already doing the fundamentals well, while also addressing the limitations of the current research and how to think about bias when science and industry intersect.The conversation then shifts to resistance training, where Brad shares key takeaways from the ACSM position stand he led, including what matters most for strength, hypertrophy, and health, and what people can probably stop overthinking.It's a balanced, evidence-informed conversation about mitochondrial health, supplementation, strength training, and the practical foundations that still matter most.Brad Currier is the Science Lead at Timeline Nutrition, where his work focuses on translating emerging research on mitochondrial health into practical, evidence-based applications. In particular, he has been closely involved in the science and communication around Urolithin A, the active ingredient in Mitopure, and its potential role in supporting muscle function, cellular energy, and healthy ageing.With a background in exercise science and resistance training research, Brad brings a dual lens to his work—combining performance-focused insights with a broader interest in longevity and metabolic health. He has contributed to large-scale evidence syntheses in resistance training, helping clarify what actually matters for strength, hypertrophy, and overall health, and where the field may have overcomplicated things.At Timeline, his role sits at the intersection of research, education, and application, helping bridge the gap between mechanistic science, clinical relevance, and real-world use—particularly as interest grows in interventions that support muscle and mitochondrial function across the lifespan.Brad Currier https://www.instagram.com/bradcurrier.phd/• ACSM Position Stand on Resistance Training (2026) - https://journals.lww.com/acsm-msse/fulltext/2026/04000/american_college_of_sports_medicine_position.21.aspx• Timeline Nutrition - https://www.timeline.com• Curranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzContact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

Soon-to-arrive drugs promise to address elevated Lp(a); Best natural alternatives to repel mosquitoes and ticks; When cancer treatments cause osteoporosis; Organoids and computer simulations promise to reduce the toll of live animal experimentation; Land snails and pythons yield clues for new drug development; Shortfall in doctors accelerated by early retirement as physicians cite “hassle factor.”

Navigating midlife body changes can feel like waking up in a completely different body, even when your routine hasn't changed. Around 15% of active women transition through menopause without experiencing significant weight gain, finding that standard calorie deficits and exercise still work. However, the vast majority notice that previously effective fitness and nutrition habits suddenly stop yielding results. This shift is highly associated with a changing hormonal environment—specifically decreasing estradiol and declining progesterone levels—rather than just the natural ageing process. While it seems logical that hormone replacement therapy (HRT) would be the perfect fix, the reality is much more complex. HRT yields highly variable results for body composition; it helps some lose fat, has no impact on others, and can even cause weight gain. WHAT YOU'LL LEARN Approximately 15% of active women navigate menopause without significant weight gain and can still successfully lose weight using standard calorie deficits. For many women, the fitness and nutrition strategies that worked five or ten years ago become noticeably less effective during midlife. Accelerated fat gain during menopause is heavily associated with decreasing estradiol and progesterone levels, alongside rising follicle-stimulating hormone (FSH). Distinguishing between weight gain caused by natural ageing and weight gain caused specifically by menopause remains a complex challenge for researchers. Hormone therapy does not offer a universal solution for weight management, with individual results varying wildly from fat loss to unexpected fat gain. VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group, details his paper “Energy Allocation Resilience and Endocrine Integration” in the International Journal of Molecular Sciences. He introduces the Energy Allocation System (EAS), which emphasizes how the body allocates energy—not just produces it—and links many symptoms to impaired bioenergetics and resilience. They discuss mitochondria as energy generators and cellular signaling hubs, the integrated stress response and endocrine coordination (HPA axis, thyroid, gonads), and mitohormesis/eustress (exercise, fasting, heat/cold, circadian “zeitgebers”). Schuler explains nuanced testing for fatigue (diurnal cortisol, CGM patterns, thyroid markers including T3/reverse T3) and a case of a perimenopausal woman where oral contraceptives and cortisol dysregulation affected glucose patterns. They cover mitochondrial support (removing obstacles like pollutants/antibiotics, triglycerides, carnitine, dietary fats, micronutrients) and pacing/sequencing lifestyle interventions.

You won't believe this new medical use for Classic Coca-Cola; The solution for menopausal sleep problems goes beyond mere hormone replacement; Paxlovid strikes out vs. Covid in new trials; Pesticide exposure may explain rising colorectal cancer rates in young people; Big Food touts faulty study that claims healthier food regulations will cost consumers; Higher aerobic fitness boosts size of the brain's memory centers—as does memorizing London taxi routes. 

Anurag Singh MD, PhD. is a physician, researcher, immunologist, and one of the leading voices behind the science of Urolithin A – a gut microbiome metabolite. Urolithin A is crucial for mitochondrial health by stimulating mitophagy. Dr. Singh breaks down the science and explains his extensive research into how this postbiotic compound could play a major role in cellular energy and longevity. Whether you’re an athlete, a health optimizer, or just curious about the future of longevity science, this conversation with Dr. Anurag Singh is packed with cutting-edge, evidence-based insights you won’t want to miss. Today on The Lab Report: 3:05 Meet Dr. Anurag Singh and learn about Urolithin A 6:45 Substrates, prevalence, and specific gut commensal bacteria 9:40 Mitophagy and mitochondrial health 12:55 Immunology and aging 15:35 Urolithin A and muscle mass 17:45 Academic research a-ha moments 20:15 Clinical benefits of Urolithin A 23:00 Food based approach vs. supplementation 25:25 Safety and contraindications 27:00 Ranking your supplement stack 29:10 The Fireball Additional Resources: Timeline Mitopure Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on X, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Health expert and Parsley Health founder Dr. Robin Berzin joins host Angela Foster to discuss a proactive approach to managing perimenopause and menopause. Dr. Berzin emphasises the importance of listening to our bodies, tracking whole-body symptoms over time using tools like the Parsley Symptom Index, and utilising continuous blood work to catch early hormonal shifts before standard symptoms like hot flashes begin. WHAT YOU'LL LEARN How to actively listen to your body and identify early, subtle signs of perimenopause before major symptoms like hot flashes even begin. How tracking whole-body symptoms and blood work over time reveals personalised hormonal trends that one-off lab tests completely miss. How optimising sleep consistency and monitoring heart rate variability (HRV) with wearables can lower your biological age and improve stress resilience. How a personalised combination of proactive lifestyle tracking, lab data, and tailored hormone therapies can naturally regulate your metabolism, mood, and energy levels. VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

What if the reason you feel more tired, foggy, or just not like yourself anymore… isn't just hormones or “getting older” — but something happening deeper in your body? In this episode, I sit down with Jen Scheinman, a registered dietitian with over 25 years of experience in nutrition and healthy aging and Director of Science Communications at Timeline Nutrition. Jen is one of the leading educators on Urolithin A — a postbiotic compound found in Mitopure — and its role in mitochondrial health, cellular renewal, and longevity. Beyond Timeline, she also runs her own practice, Next Jen Health, where she helps women optimize vitality through the menopause transition and beyond. We explore a part of our health that most of us have never really been taught to think about—our mitochondria, the energy centers inside our cells — and why so many women start to feel a shift in their 30s and 40s, when the things that used to work suddenly don't. Jen breaks down the science in a way that actually makes sense, connecting fatigue, brain fog, and changes in your body to what's happening at the cellular level. We talk about why diet and exercise can stop working the way they used to, how your gut and environment impact your energy, and what's really going on beneath the surface as we age. We also explore the difference between living longer and actually feeling good while you do it — and what it looks like to support your body in a way that aligns with how it truly works. This conversation isn't about quick fixes. It's about understanding your body on a deeper level so you can start to feel like yourself again. Mitopure now starts at just $79. Go to ⁠timeline.com/healwithkelly to get 20% off Mitopure supplements and Skincare with code HEALwithKelly. Key Moments You'll Love ✨ :

Why Isn't Everyone Talking About Mitochondria? with Jennifer Scheinman Most people learned the word in 10th-grade biology and never thought about it again. That, argues registered dietitian and longevity expert Jennifer Scheinman, is exactly the problem. In this episode of Why Isn't Everyone Doing This?, Emily Fletcher sits down with Jennifer, a nutritionist with over 25 years of experience and a longevity expert at Timeline, the company behind the clinically studied Urolithin A supplement MitoPure, for a conversation that reframes everything from fatigue to aging to consciousness through the lens of your cells. Jennifer explains how the mitochondria work, why their decline accelerates in your 40s and 60s, and what you can actually do to slow that process. They cover the 12 biological hallmarks of aging, the cellular recycling system (mitophagy) that breaks down over time, why so many people can't produce Urolithin A on their own, and how to evaluate supplements in an industry the FDA doesn't fully regulate. They also connect it all to meditation, to stress, to perimenopause, and to the Greek myth of Persephone and the pomegranate. And at the very end: a fact about mitochondrial DNA that changes the way you think about your mother, your grandmother, and the feminine line you carry. In this episode, they explore: – What mitochondria are, what they do, and why they're more like a CEO than a powerhouse – The cellular recycling process (mitophagy) and why it slows with age – Zombie cells, inflammaging, and the 12 hallmarks of biological aging – Why aging isn't linear — and what the research says about the 40s and 60s – How meditation reduces the inflammation driving cellular decline – Urolithin A: what it is, how your gut should be making it, and why most people's isn't – How to read supplement labels and avoid "fairy dusting" and borrowed science – Timeline's clinical research: what the trials showed and how long results take – The topical MitoPure skincare line and UV-related skin aging – Why mitochondrial DNA is inherited exclusively through the maternal line – Persephone, pomegranates, 108 seeds, and the convergence of myth and molecule Key Moments: 00:00 — The question that opens the episode 03:00 — Mitochondria 101: what they really are 08:15 — Every cell except red blood cells runs on mitochondrial energy 10:00 — Mitophagy: your body's cellular cleanup crew 13:00 — Why aging accelerates in the 40s and again in the 60s 16:00 — Zombie cells and the inflammaging hallmark 19:00 — Meditation's effect on cellular inflammation — the Ziva link 25:00 — Fasting and perimenopause: what the science says for women 29:00 — How to evaluate supplements when labels aren't regulated 35:00 — Urolithin A: gut-made, often missing, and why it matters 40:00 — Why food alone won't get you there (6 cups of pomegranate juice a day) 44:00 — The clinical trials: muscle endurance at 2 months, strength at 4 months 53:00 — Urolithin A + exercise: a likely additive effect 58:00 — How Dr. Gabrielle Lyon first put this on Emily's radar 01:01:00 — The skincare line: bringing MitoPure topically 01:03:00 — Mitochondrial DNA and the matrilineal inheritance 01:05:00 — Persephone, pomegranates, and the place where science meets spirit About Jennifer Scheinman Jennifer Scheinman is a registered dietitian and nutritionist with over 25 years of experience. She is a longevity and nutrition expert at Timeline, the company behind MitoPure — a clinically researched Urolithin A supplement backed by over $50 million in human studies. Her mission is making the science of longevity accessible, practical, and connected to how you actually feel. Follow Jennifer: @jenscheinmanrdLearn more: https://timelinenutrition.com This episode is sponsored by Timeline. Support your mitochondrial health and get 20% off Mitopure at http://timeline.com/ziva. ✨ The Portal is open. If this conversation stirred something in you — around energy, consciousness, and what becomes possible when your body is resourced — you may be ready for what's next. The Portal is Ziva's newest immersive experience, with a VIP weekend for those who want to go further. If you feel the pull, follow it.

Hydrogen water—breakthrough or scam? Osteoporosis fixes; Nattokinase for cardiovascular prevention; Why vitamin D helps a subset of diabetics; When oral vitamin D doesn't work, sublingual D may normalize blood levels; Vitamin D found beneficial for colitis; Why fructose stokes food cravings; Flawed fluoridation study claims no IQ harms to kids.

Full Show Notes: https://bengreenfieldlife.com/sisson2026 In this episode with Mark Sisson, you'll discover why VO2 Max may be overrated as the gold standard for longevity, and why chasing it cost Mark 32 pounds of muscle and the real-world function that actually matters. You'll explore his "Old Man Olympics" framework: a decathlete's approach to fitness at 72, spanning strength, speed, balance, and endurance. You'll also get his take on cold plunging, alcohol, biohacking, AI, and find out why foot health may be the single most overlooked lever in your longevity toolkit, from bunions to glute activation to big toe function. Mark Sisson ignited the ancestral health movement with Mark's Daily Apple and The Primal Blueprint, popularized keto and intermittent fasting with The Keto Reset Diet and Two Meals a Day, and sold Primal Kitchen to Kraft Heinz for $200M. He now runs Peluva, a toe-separated shoe company built around restoring foot strength and healthy gait, and is the author of Born to Walk.

We tend to think of heart disease, cancer, and Alzheimer's as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose research, including work on compounds like urolithin A, is helping reshape how we think about aging and long-term health. We explore why aging may be the biggest driver of chronic disease and what that means for how you approach your health. Watch the full conversation on YouTube, or listen wherever you get your podcasts. We unpack: • How your immune system becomes both overactive and less effective over time • What chronic inflammation is doing inside your body and how to start bringing it back into balance • Why cellular energy and mitochondrial health are key to repair and recovery • How your microbiome shapes inflammation, immunity, and long-term health • The daily habits that impact longevity most and where people get it wrong This conversation reflects a shift in how we think about health, moving beyond treating disease to understanding what's driving it in the first place. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, Seed, BIOptimizers, BON CHARGE, Paleovalley and Big Bold Health. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to paleovalley.com/hyman to save 15% off your first order today. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. (0:00) Biological age vs. cholesterol in heart disease and chronic disease risk (0:50) Introduction of Dr. Eric Verdin and his work (1:23) Sponsor: Brain Shaping Academy (1:51) Sponsor: Mitopure (2:54) Sponsor: Seed (3:48) Welcoming Dr. Eric Verdin and longevity framing (5:42) The geoscience hypothesis and modifying age as a risk factor (8:21) Early-stage interventions in aging and potential for life extension (9:56) Longevity skepticism and practical steps for today (11:20) Mitochondria, inflammation, and hallmarks of aging (17:20) Mitochondrial DNA, inflammation, and immune system aging (22:17) Innate vs. adaptive immunity and immune aging (28:47) Strategies to combat immune aging (33:07) Gut health, inflammation, and foundational elements of longevity medicine (38:20) Social connections, sociogenomics, and cellular energy in aging (46:29) Cellular repair systems and postbiotics (50:33) Sponsor: Paleo Valley (52:34) Sponsor: Big Bold Health (53:23) Urolithin A, immune rejuvenation, and longevity interventions (59:08) Longevity and functional medicine approaches (1:02:27) Big data, AI, and the evolution of medicine (1:04:26) Microbiome, diet, and gut health (1:06:14) Measuring biological age and biological clocks (1:09:37) Future of health monitoring and closing remarks

When you hit your 40s, you start catching colds more easily, wounds take longer to heal, and you feel rundown even after a full night's sleep. Your doctor will tell you "it's just aging." They're wrong.It's actually your immune cells suffocating on toxic waste because their power plants—your mitochondria—are breaking down.In this video, I explain the exact biological mechanism behind "immune aging" and why your body's natural cleanup system (mitophagy) stalls out in your 40s and 50s. More importantly, I'm sharing the breakthrough compound scientists discovered that actually reverses this. It's a molecule called Urolithin A, originally found in pomegranates.I dive into the massive problem with trying to get this molecule from food (only 30% of people have the right gut bacteria to even make it), and the 15 years of human clinical trials behind Mitopure—the supplement that bypasses your gut completely. I even share why I spent $100,000 on an extreme T-cell procedure before I knew I could just take this to get a younger immune system in 28 days.00:00 – Immune Decline After 4000:39 – Why Immune Cells Weaken01:17 – The Role of Mitochondria02:25 – Mitophagy & Its Decline05:45 – The Ancient Fruit: Pomegranates06:39 – The Problem With Pomegranates07:19 – Urolithin A as a Supplement08:33 – Trial Results09:58 – About MitoPure10:46 – Call to ActionThank you to our sponsors!-GOT MOLD? | Go to http://gotmold.com/shopand use DAVE10 to save 10% and see what's in your air.-Superstratum Labs | Get Dave's exact home mold detox kit and save 10% at superstratumlabs.com/products/dave-iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVEConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Full Show Notes: https://bengreenfieldlife.com/nadplus In this fascinating episode, Dr. Nichola Conlon, molecular biologist and founder of Nuchido, breaks down what NAD actually is, what it does inside your cells, and why most popular strategies for boosting it, including NAD IVs, patches, and high-dose NR or NMN, may be fundamentally flawed based on molecular biology. You’ll discover why NAD declines by half every 20 years, why the NAMPT enzyme and not a shortage of raw material is the real bottleneck, and why flooding the body with precursors without fixing the salvage pathway can actually strain your methylation pathways rather than raise NAD. You’ll also explore how inflammation through the cluster of differentiation 38 (CD38) enzyme silently drains NAD faster than almost anything else, what a gold standard double-blind placebo-controlled crossover clinical trial on Nuchido TIME+ actually showed, and why NAD sits at the intersection of energy production, cellular repair, sleep, skin health, and biological aging. Dr. Nichola Conlon (BSc, MRes, PhD) specializes in cellular aging. After a career in drug development, Dr. Nichola founded Nuchido, driven by her belief that cutting-edge science should not lie hidden. At Nuchido, Dr. Nichola’s work focuses on delivering disruptive innovation in the field of anti-aging, rejuvenation, and healthspan. It has led to the development of Nuchido TIME+, a dietary supplement clinically proven to boost NAD+ and reverse biological age. Unlike standard precursors such as NMN or NR, Nuchido TIME+ uses a systems-based approach to target the root causes of NAD+ decline.

Full Show Notes: bengreenfieldlife.com/lnannette/ In this "Best of LIFE Network" episode with Annette Verpillot, you'll explore a neuromechanical approach to improve communication between your brain and your body, targeting the compensatory movements and postural adaptations that hold you back from pain-free, efficient movement. Annette is the founder of Posturepro (use code BOUNDLESS to save 15% off), a health company specializing in restoring the brain-body connection through some of the world’s most advanced rehabilitation and injury prevention techniques. Additionally, she actively works with clients, professional athletes, trainers, practitioners, researchers, and law enforcement officers to develop solutions that promote a healthy, long, and pain-free life. Annette actively participates in research on posture, health, and performance, and her recent collaboration with McGill University was presented at Harvard Medical School and La Sorbonne University in Paris. Episode Sponsors: Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. Their products can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Formula IQ: Recuperate IQ by Formula IQ is a comprehensive copper supplement designed to support mitochondrial energy, iron balance, and metabolic health by pairing bioavailable copper with essential cofactors your body needs for proper utilization, which is especially crucial if you've been under chronic stress or supplementing with high-dose zinc. Try it at formulaiq.com and use code BEN for 10% off. Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Mitopure now starts at $79, when you go to timeline.com/BEN. Just Thrive: Just Thrive Probiotic is the only probiotic clinically proven to arrive 100% alive in your gut, wrestling in less bloat, better energy, and even clear skin. Digestive Bitters packs 12 science-backed herbs in one tasteless capsule that jumpstarts your digestion and supports GLP-1 production so cravings don’t control you. Visit justthrivehealth.com/BEN and save 20% with promo code BEN. See the difference for yourself or get a full product refund, no questions asked.See omnystudio.com/listener for privacy information.

Dr. Rhonda Patrick, PhD, is a biomedical scientist and public science educator. She shares the exercise, nutrition, supplementation and lifestyle practices linked to better health and lower disease risk including specific cardio and resistance training routines, when and why to do intermittent fasting, ways to lower visceral fat, omega-3 sourcing, creatine for brain and muscle and peptides such as BPC-157. It's broad and thorough coverage of how to build a total health program tailored to your goals and individual biology. Read the show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman Lingo: https://hellolingo.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Mateina: https://drinkmateina.com/huberman Timestamps 00:00:00 Rhonda Patrick (00:02:40) Competition, Jumping Rope, Rope Flow (00:06:49) Rhonda's Exercise Routine, Cardiovascular & Resistance Training (00:12:30) Cognitive & Physical Benefits of Exercise, Serotonin & Impulse Control (00:14:40) Sponsors: Our Place & Lingo (00:17:03) Phones While Training? (00:18:45) Rhonda's Strength Training, Low-Reps, Modifications, Mental Resilience (00:27:00) Daily Protein Intake, Intermittent Fasting, Processed Carbohydrates (00:33:32) Lipopolysaccharide (LPS); Gut Permeability, Gluten; Cardiovascular Health (00:42:58) Sponsor: AG1 (00:44:21) Tight Junctions, Gut, Neuroinflammation (00:47:26) L-glutamine, Immune System, Cancer Risk (00:54:55) N-acetylcysteine (NAC), Vitamin E; Antioxidant Balance, Reductive Stress (01:00:08) Starch, Tool: Bedtime Fast & Cardiovascular Health (01:03:36) Cortisol, Intermittent Fasting Benefits (01:08:09) Cortisol, Train Fasted?; Hormones, Visceral Fat (01:13:35) Visceral Fat, Perimenopause/Menopause, Insulin Resistance in Brain & Body (01:21:13) Sponsor: LMNT (01:22:33) Cortisol & Sleep (01:25:42) Intermittent Fasting, Metabolic Switch, Ketones, Muscle Loss? (01:36:47) Tools: Logic-Based Habits; Daily Metabolic Switch; Exercise, Autophagy (01:45:06) Exercise After Poor Sleep?; Training Breaks (01:52:47) Tool: "Exercise Snacks"; Sedentary Lifestyle & Cardiorespiratory Fitness (02:03:31) Sponsor: Function (02:05:16) Creatine, Dose, Resistance Training, Cognitive Function (02:17:43) Biology; Creatine; Supplement Safety (02:25:18) Omega-3s, Inflammation, Cancer Risk, Vitamin D; Trans Fat (02:36:52) Magnesium Threonate vs Bisglycinate, Sleep, Cognitive Benefit; Vitamin D (02:45:46) Supplement Types, Multivitamin, Coenzyme Q10, Urolithin A, Sulforaphane (02:55:10) Microplastics (02:57:26) Sponsor: Mateina (02:58:28) BPC-157, NMN, NR, Tool: Evaluating Supplements, Safety, Sources (03:06:28) L-Carnitine, Alpha-GPC, Nicotine, GABA & Ketogenic Diet (03:15:20) Nattokinase; Microplastics, Water Bottles; Seed Oils (03:22:21) Sauna, Creatine for Kids?, Bananas, Tool: Evaluating Studies (03:28:37) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimCresset family office services for CEOs, founders, and entrepreneurs: CressetCapital.com/TimTimestamps:[00:00:00] A meditative start.[00:02:19] Reflecting on our second Zen retreat in Santa Fe with Henry Shukman.[00:04:08] Ketone liver warnings and eggplant allergies: The perils of raiding Kevin's fridge.[00:08:06] “Just be still” — three simple words that miraculously shut down my OCD.[00:13:54] Is meditation secretly vagus nerve stimulation?[00:20:17] DIY vagus nerve stim for $25 vs. Kevin's $900 ear clip.[00:24:57] HeartMath and watching your HRV move in real time.[00:27:57] Marching toward 50: balance boards and the end of jiu-jitsu.[00:31:26] Tony Hawk snowboarding Hokkaido with screws in his hip.[00:33:01] Slacklining and why your nervous system needs sleep cycles.[00:35:19] Bertolotti's Syndrome: My six-year back pain gets a name.[00:37:09] The nerve block test: everything wrong, zero pain.[00:44:10] Abrahangs tendon protocol: 10 seconds on, 50 off.[00:46:24] The NUG: a pocket hangboard for travelers.[00:48:31] Craig Mod's Japanese toothbrush and Toaster's cameo.[00:50:45] Kevin's $92 vintage fire jacket: Blue Heritage Japan.[00:54:26] Podcast picks: The Power Broker and STEM Talk.[00:56:20] Alzheimer's: A plaque or mitochondrial problem?[00:57:30] 10 grams of ketones turns one-word answers into sentences.[00:58:40] Methylene blue on Amazon: 120 years of research, zero guardrails.[01:02:36] Bredesen Protocol, APOE genotyping, and a cognitive comeback.[01:05:32] Photobiomodulation: $30k laser to the forehead.[01:07:55] Urolithin A and the high price of mitochondrial upkeep.[01:14:56] Recipe for disaster pants: espresso + creatine + MCT oil.[01:17:39] Norwegian 4×4 training and lactate as a brain lever.[01:23:15] Blood flow restriction bands and schwantz ring koans.[01:29:08] Hummingbirds named Sunset and squirrel obstacle courses.[01:32:06] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.