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Paring Down: Realistic minimalism to live more intentionally
Figuring out what to do with all our stuff AND finding the time & energy to do it is one of the biggest hurdles to decluttering. Here are some things I cover in this episode: • The Goodwill controversy • How to break free from perfectionism that paralyzes us • 4 questions to help you determine which donation centers to pick • The best principle I've ever heard for how to handle overwhelming decisions (shout out to Kendra Adachi from The Lazy Genius Way) • Tips for donating, selling, & posting items online ...and more. PARING DOWN (SHANNON LEYKO): Instagram: @shannonleyko TikTok: @shannon_leyko Youtube: https://www.youtube.com/@shannonleyko Facebook: www.facebook.com/shannonleyko.paringdown Weekly Newsletter: The L.E.S.S. Express MENTIONED THIS EPISODE: The Lazy Genius Way by Kendra Adachi pickupplease.org PARING DOWN RESOURCES: Paring Down Newsletter: The L.E.S.S. Express Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: 20% off at Cozy Earth: www.cozyearth.com - code PARING Use code PARING at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! 50% off MeUndies at www.meundies.com/paring - code PARING 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Most fat-loss advice focuses on the scale — but what if that's the wrong metric entirely? In this episode, Vanessa Spina is joined by Dr. Scott Forbes, exercise physiologist and professor at Brandon University, whose research challenges many of the assumptions behind traditional weight-loss approaches. Dr. Forbes has authored and co-authored numerous randomized controlled trials and large meta-analyses examining how training style, protein intake, creatine supplementation, sleep, and aging influence fat loss, muscle retention, and metabolic health. Rather than chasing weight loss, this conversation explores what happens when the goal shifts to body recomposition — losing fat while preserving or building muscle — and why that distinction changes everything. In this episode, we explore: Why weight loss and fat loss are not the same thing The surprising differences between cardio, resistance training, and combined approaches Why some people lose weight but stall metabolically How protein and creatine fit into a muscle-centric fat-loss strategy Why fat loss becomes harder with age — and what still works A largely overlooked factor that influences where fat is stored If you've ever done "everything right" and still felt stuck, this episode offers a science-backed reframe that may completely change how you approach fat loss.
Should women take HRT even if they're not bothered by menopause symptoms? It's a question many women ask – especially those with a family history of osteoporosis. Liz shares her take. In this episode: How can I treat bloating and constipation?Are NAD+ and Urolithin A supplements worth taking?What's the best way to fade a facial scar?Should I invest in an air purifier? Do I still need HRT if I have no symptoms?Resources mentioned: Magnesium glycinate supplementsDigestive bittersProbiotic supplementsNAD+ supplementsUrolithin A supplementsFushi Wellbeing rosehip oilSunlighten red light therapy deviceCollagen supplementsVitamin K2 + D3 supplementsOmega-3 supplementsDr Sajjad Rajpar podcast about oestrogen gel and wound healing Balance menopause symptom tracking appGet in touch with a question for Liz:Email: podcast@lizearlewellbeing.comWhatsApp: 07518 471 846More from Liz:Preorder Liz's NEW book – How to AgeA Better Second Half Follow Liz on InstagramFollow Liz Earle Wellbeing on InstagramSome links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. Hosted on Acast. See acast.com/privacy for more information.
Full Show Notes: bengreenfieldlife.com/496 In this episode, I share my personal experiences with advanced medical therapies in Austin and answer your questions about hydrogen for health, including the science behind it and practical ways to use it—from tablets to inhalation and baths. I also give advice on how to find a trustworthy hormone doctor, what credentials to look for, and recommend a few experts and clinics that I actually trust, based on my wife’s HRT journey. On the research front, I break down whether alcohol is really that harmful (it’s often overblown if you’re healthy and moderate) and highlight new findings that chronic cannabis use can mess with your memory and processing. I offer perspective on the melatonin-heart health headlines (don’t panic if you use it sensibly) and explain why microplastics fears might be overhyped. Episode Sponsors: Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Don’t let another year go by feeling less than your best. Grab 35% off your one month subscription of Mitopure Gummies at Timeline.com/BEN35 while the offer lasts. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. CAROL Bike: The science is clear—CAROL Bike is your ticket to a healthier, more vibrant life. And for a limited time, you can get $100 off yours with the code BEN. Don't wait any longer, join over 25,000 riders and visit carolbike.com/ben today. Aires Tech: Protect your home, office, and body from EMF with some of the highest EMF-shielding technology ever created. Aires Tech is offering a 30% discount to all Ben Greenfield Life listeners at airestech.com/ben by using code BEN30. Boundless Bar: If you’re ready to fuel workouts, sharpen your focus, and support whole-body vitality, grab your Boundless Bars now at boundlessbar.com —and save 10% when you sign up for a Boundless Bar subscription. TRIUMPH Coaching: Join me for one-on-one coaching with me and my hand-picked team, custom-built around your labs, your lifestyle, and goals, until you actually hit them. No guesswork. Just results. If you’re finally ready to stop wasting time and money and start living the boundless life you know is possible, go to jointriumphcoaching.com and book your call.See omnystudio.com/listener for privacy information.
Today, I'm joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described "curious cardiologist" who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it? Episode Timestamps: Welcome to Longevity & episode setup … 00:00:00 Dr. Bhojraj's shift from ER cardiology to prevention … 00:06:30 Why most heart attacks aren't caused by big blockages … 00:09:15 Stress, nervous system load & heart attack risk … 00:13:10 CIMT explained: what it measures (and what it misses) … 00:26:40 Calcium scores vs CT angiograms … 00:35:45 CLEERLY scan: seeing dangerous soft plaque … 00:38:45 Can plaque actually regress? … 00:41:55 When heart scans make patients less afraid … 00:44:05 When should you test — even without symptoms? … 00:45:50 Why age 45 is a major cardiovascular inflection point … 00:47:10 Hormones, estrogen loss & women's heart risk … 00:50:10 Why cardiology still misunderstands women … 00:54:30 Small dense LDL, ApoB & oxidized cholesterol … 01:02:00 Why fixing inflammation matters more than numbers … 01:05:50 Our Amazing Sponsors: Regenerive - Built around clinically validated Longufera (Ash X4) to support core aging pathways—so it's not just "healthy aging" in theory. Go to regenerive.co and use code NAT25 to save 25% Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026. PW1 by Puori — A clean, high-quality whey protein that's third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Paring Down: Realistic minimalism to live more intentionally
If you've ever struggled with letting go of sentimental items after loss, I hope today's episode gives you both validation and encouragement. I talk with Krista St. Germain of the Widowed Moms Podcast, who lost her husband to a drunk driver, and we explore the emotional weight of decluttering a loved one's belongings. You'll hear: • mindset shifts around grief • what it means to let go in a way that "feels like love" • why there's no one-size-fits-all approach to releasing sentimental items This comforting conversation offers gentle guidance for decluttering when space is limited or when keeping certain items no longer feels supportive for your wellbeing. PARING DOWN SOCIALS (SHANNON LEYKO): Instagram: @shannonleyko TikTok: @shannon_leyko Youtube: https://www.youtube.com/@shannonleyko Facebook: www.facebook.com/theexpertbeginner KRISTA ST-GERMAIN The Widowed Mom Podcast Episode: What to Say and What Not to Say to a New Widow Website: www.coachingwithkrista.com Instagram: @lifecoachkrista PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: 20% off at Cozy Earth: www.cozyearth.com - code PARING Use code PARING at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! 50% off MeUndies at www.meundies.com/paring - code PARING 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, I'm joined by Dr. Catherine Clinton to explore how circadian biology, light exposure, and cellular electrical charge regulate metabolism, hormones, and fat loss — often beyond calories alone. We discuss how morning light impacts leptin signaling, insulin sensitivity, cortisol, and melatonin, why modern indoor living disrupts metabolic health, and how maintaining a strong negative cellular charge is critical for mitochondrial function. We also cover red and infrared light therapy, optimal timing, metabolic benefits, and key considerations during pregnancy — plus how to integrate protein intake, calories in vs. calories out, and resistance training with circadian alignment for sustainable fat loss. Topics include: Light exposure and leptin signaling Circadian rhythm and fat loss Cellular charge and mitochondrial health Grounding and infrared light Red light therapy timing and pregnancy considerations Balancing calories, protein, and training with circadian biology
As you age, your thymus produces fewer newly formed cells responsible for responding to unfamiliar pathogens, reducing your immune system's adaptability. This shift, combined with persistent inflammation, defines the core features of immune aging Urolithin A, a postbiotic compound, stimulates mitochondrial renewal in aging immune cells. A recent study shows it can increase naïve-like T cells and strengthen immune surveillance in just four weeks of supplementation Clinical findings show that urolithin A boosts mitochondrial renewal pathways, increases markers linked to mitochondrial biogenesis, and improves immune cell metabolism Beyond immune health, studies reveal that urolithin A influences cancer pathways, enhances muscle strength and endurance, improves fatty liver markers, and reshapes metabolic signaling involved in obesity and insulin resistance Beyond using urolithin A, you can also support your mitochondria by lowering linoleic acid intake, eating the right carbohydrates, limiting environmental toxins, and supporting NAD⁺ production with niacinamide
Is mitochondrial decline the hidden blueprint that decides how fast your body ages? Josh Trent welcomes Dr. Brad Currier, PhD, Clinical Scientist, to the Wellness + Wisdom Podcast, episode 793, to unpack how mitochondrial health is passed through generations, why modern environments and sedentary living accelerate aging, how mitophagy and Urolithin A restore cellular energy, why gut health blocks or enables longevity, and how exercise plus targeted supplementation can fundamentally shift mood, vitality, and long term health from the inside out. 30% Off Mitopure (Timeline Nutrition) The first clinically tested Urolithin A supplement Mitopure® is a highly pure form of Urolithin A, a postbiotic clinically shown to energize cells, increase muscle strength, and improve endurance. And this is just the beginning. New studies continuously explore and prove the incredible potential of Urolithin A. Few people can get enough Urolithin A from diet alone. Mitopure unlocks 6X the dose of Urolithin A when compared to dietary sources such as pomegranate juice, without the sugar. Mitochondria, our cellular powerhouses, are constantly renewed to fulfill the vast energy demands of cells. As we age, mitochondrial function declines, starting as early as our 30s. Mitopure stimulates the mitochondrial renewal process to protect cells from age-associated decline. Get Mitopure Today Save 30% with code JOSH at checkout In This Episode, Dr. Brad Currier Uncovers: [01:10] How to Optimize Mitochondrial Health How our mitochondrial DNA is passed from mothers to children. The functions of mitochondria in the human body. How our environment affects our mitochondria. Why UV radiation from the sun damages proteins in our cells. How sedentary lifestyle impact mitochondrial health. Resources: Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH [08:35] Intergenerational Mitochondrial Health How mitochondrial health is impacted by multiple generations that came before us. Why we're impacted by seven generations before us, and we impact seven generations after us. The importance of nurturing our mitochondrial health. Resources: It Didn't Start with You by Mark Wolynn [12:55] The Cause of Aging What causes faster aging. How our cells become unhealthy and age. Why our cell turnover slows down as we age. How mitochondria break down and impact our energy levels. Resources: 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul [16:55] The Importance of Urolithin A The role of postbiotics in digestion. Why we need Urolithin A for optimal health. How Urolithin A was discovered. Resources: Outwitting The Devil by Napoleon Hill [20:55] You Need to Fix Your Microbiome Why we have to take supplements to maintain our health. How the microbiome blocks production of Urolithin A. Why most people's gut microbiome is damaged. How our gut microbiome lacks diversity compared. [24:15] Gut-Brain Axis How the gut-brain axis is linked to many diseases. Why mitochondria can impact different systems of the body. The importance of supplementing Urolithin A. Why food cannot help us produce more Urolithin A. How aging affects protein absorption. [29:35] Activate Mitophagy to Stop Aging Why Mitopure is the only clinically proven supplement to activate mitophagy. The three phases of the mitochondria's life cycle. Why removing cellular residue prevents aging. How healthy mitochondria can help us live a better life. Why renewing cellular energy requires consistency. [36:05] Scientific Data Behind Mitochondrial Health How mitochondrial health impacts mood and mental health. Why Timeline Nutrition continues running new clinical studies. How repeated scientific research proves whether something truly works or not. Why they publish all of their studies online. [43:40] The Power of Exercise Why professional athletes have a higher risk of heart attack. How exercise is the best tool for health and longevity. Why combining Mitopure with exercise increases mitochondrial health. How weightlifting helps us create new cells. [50:20] The Fundamentals of Health How Brad takes care of his own health. Why exercise is the most important tool for him. The role of a good diet and sleep in our health. [55:20] Change Is Counter-Intuitive Why change can feel counterintuitive at first. The importance of allowing ourselves to feel uncomfortable. How we can't often know for sure what tools or supplements are best for us. "Poor quality food and pollutants in our environment ultimately converge on the mitochondria and have an impact on its ability to produce energy. When we have this accumulation of debris in our cells, they don't work as well and they start releasing toxins that impact cells around them. " — Dr. Brad Currier, PhD Leave Wellness + Wisdom a Review on Apple Podcasts All Resources From This Episode Dr. Brad Currier, PhD Timeline Nutrition - 30% off with code JOSH It Didn't Start with You by Mark Wolynn 781 Pedram Shojai | Anti-Aging Cult: Why Trying To Live Forever Devours Your Soul Outwitting The Devil by Napoleon Hill Josh's Trusted Products | Up To 40% Off Shop All Products Biohacking ❤️ WAVwatch - Now 15% off with JOSH100
Unlocking Mitochondrial Health: Exploring Urolithin A and Mitochondria-Boosting Supplements with Dr. Brad Currier, a senior scientist and manager of clinical trials at Timeline, a Swiss biotech company known for their product MitoPure. The conversation delves into a unique compound, Urolithin A, which is derived from pomegranates and identified as a key activator of mitophagy—the cellular process of recycling and rejuvenating damaged mitochondria. Dr. Currier elaborates on the significant health benefits of Urolithin A, including improved muscle strength, enhanced immune function, and its potential cognitive and anti-aging effects. The episode also covers topics such as the role of exercise and dietary protein in maintaining muscle health, the future potential of supplementary compounds like creatine, and highlights the newly introduced MitoPure gummies designed for convenient daily intake. Additionally, the discussion extends to the implications of mitochondrial function in various tissues, including skin and hair health.
Paring Down: Realistic minimalism to live more intentionally
Self-discipline doesn't have to feel exhausting! In today's episode, I... • Debunk 7 myths about self-discipline • Share 5 core principles for developing self-discipline • Suggest 5 specific areas to be self-disciplined about to keep a clutter-free home. If decluttering feels like a cycle you keep repeating, this episode explains why discipline isn't the enemy of an easy, enjoyable life—it's the key! PARING DOWN SOCIALS (SHANNON LEYKO): Instagram: @shannonleyko TikTok: @shannon_leyko Youtube: https://www.youtube.com/@shannonleyko Facebook: www.facebook.com/theexpertbeginner MENTIONED IN THIS EPISODE: Ep 50: The Guilt & Fear of Decluttering Gifts Ep 112: The Trap of Upgrading Our Lives PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: 50% off MeUndies at www.meundies.com/paring - code PARING 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode of the Optimal Protein Podcast, Vanessa is joined by Dr. Nick Barringer, former U.S. Army officer, researcher, Registered Dietitian, and Chief Academic Officer at Lionel University. Dr. Barringer has led cutting-edge research on protein intake, recovery, and resilience under extreme physical and psychological stress, working with tactical athletes including Army Rangers, Navy SEALs, and West Point cadets. This conversation goes far beyond the military. Dr. Barringer breaks down how women and everyday high performers can apply the same evidence-based strategies to lose fat without losing muscle, recover more effectively, and avoid the biggest pitfalls of aggressive dieting. Together, Vanessa and Dr. Barringer cut through fear-based nutrition messaging and explore what human research actually shows about protein intake, recovery, seed oils, supplements, and collagen. Get 20% off the Tone Device to try on a PSMF Day! Shop the collection HERE and use the code VANESSA Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 20% off the Tone LUX Crystal Red Light Therapy collection including the Crystal Mask and accessories the with the code VANESSA HERE Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this Tuesday Headline Brief of The Wright Report, Bryan covers political fallout from Minnesota's massive Medicaid fraud scandal, disciplinary action against Senator Mark Kelly for seditious conduct, explosive courtroom revelations from Nicolás Maduro's arraignment, rising global instability tied to Trump's Venezuela decision, and new intelligence warnings involving China, Iran, Germany, and America's food supply. He closes with encouraging medical research on immune health and cancer prevention. Tim Walz Forced Out as Minnesota Fraud Probe Explodes: Minnesota Governor Tim Walz announced he is dropping his reelection bid after becoming a liability to Democrats over the nine billion dollar Somali Medicaid fraud scandal. Federal investigators are now probing what Walz and Attorney General Keith Ellison knew and when, after state whistleblowers warned in 2018 that fraud at Feeding Our Future was obvious before any money was paid. Despite those warnings, hundreds of millions flowed to Somali nonprofits that later donated to Democratic campaigns. Prosecutors admit the fraud is so widespread that many participants may never face charges due to limited resources. Hilton Refuses to House DHS and ICE Officers: A Hilton franchise owner in Minneapolis refused rooms to DHS and ICE agents participating in an immigration crackdown, saying the hotel would not assist deportations. Corporate Hilton had not responded at the time of recording. Bryan urges listeners to remember this incident when choosing where to spend their travel dollars. Mark Kelly Punished for Seditious Conduct: Defense Secretary Pete Hegseth reduced Senator Mark Kelly's military retirement rank and pay after Kelly called on service members to refuse illegal orders from President Trump but could not identify any such orders. Hegseth said Kelly's actions constituted reckless misconduct and confirmed investigators are evaluating whether Kelly could be recalled to active duty for prosecution under military law. Maduro Pleads Not Guilty as Indictment Stuns: Former Venezuelan president Nicolás Maduro pleaded not guilty in Manhattan, declaring himself innocent and still the legitimate leader of Venezuela. Federal prosecutors released a detailed indictment outlining twenty-five years of cocaine trafficking, kidnappings, beatings, and murders ordered by Maduro and his family. His vice president, Delcy Rodríguez, vowed to resist the United States and declared Maduro a hostage, while Marxist guerrilla groups threatened attacks on Americans. Trump's Venezuela Decision Sends Shockwaves: The Wall Street Journal reports that President Trump repeatedly tried to negotiate Maduro's peaceful exit before losing patience after public taunts. His decision to authorize the capture has rattled regimes worldwide, including Iran. Reuters reports Iranian officials now fear Trump will act decisively if protests escalate, prompting the Ayatollah to quietly prepare escape plans to Russia along with billions in assets. China's Espionage Footprint Near U.S. Bases: A Chinese intelligence-linked individual owns two golf courses near Barksdale Air Force Base in Louisiana, home to America's nuclear bomber force. Chinese media openly described the courses as networking hubs for U.S. political and business elites. Bryan warns that such properties create serious espionage and sabotage risks, similar to a Chinese-owned trailer park near Whiteman Air Force Base in Missouri. Threats to America's Food Supply: A new screwworm outbreak in Mexico threatens U.S. cattle just as Brazil reduces its breeding herd and America's cattle numbers hit historic lows. Bryan warns beef prices are likely to remain high for several years and advises listeners to stock freezers when possible. Left Wing Terrorism Returns in Germany: German officials warn left-wing terrorism is intensifying after radicals sabotaged power infrastructure in Berlin and Brandenburg, cutting electricity to forty-five thousand people. The attackers vowed to escalate assaults on oil and gas infrastructure nationwide. Promising Medical Research: German researchers found that supplementing with 1,000 milligrams of Urolithin A for 28 days significantly rejuvenated aging immune systems by restoring mitochondrial function. UK scientists also reported that ten minutes of intense daily exercise can slow or reverse colon cancer growth by triggering DNA repair and reducing inflammation. "And you shall know the truth, and the truth shall make you free." - John 8:32 Keywords: January 6 Wright Report, Tim Walz Medicaid fraud Minnesota, Feeding Our Future whistleblower Ellison, Hilton refuses ICE DHS rooms, Mark Kelly retirement demotion Hegseth, Maduro indictment Manhattan drug trafficking, Delcy Rodríguez resistance, Trump Venezuela decision global impact, China espionage Barksdale Air Force Base, screwworm outbreak beef prices, Germany left wing terrorism infrastructure attack, Urolithin A immune system study, exercise colon cancer DNA repair
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comAre your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and Chief Medical Officer at Timeline, to discuss a groundbreaking discovery: the gut-muscle-immune axis. While we often focus on muscle mass for longevity, new research published in Nature Aging reveals that our immune system undergoes a similar decline, with youthful sentinel cells (naive CD8 T-cells) dropping by 75% as we reach age 50. Dr. Singh explains how mitophagy —the targeted recycling of damaged mitochondria—is the key to "rewiring" an aging immune system to fight infection 20% more effectively. In this episode: Alzheimer's of the Muscle: Why sporadic inclusion body myositis (sIBM) is often misdiagnosed as simple aging. The Power of Urolithin A: How this postbiotic compound induces mitophagy to increase mitochondrial abundance by 20% in just 28 days. Immune Imprinting: Why children get 6-8 colds a year while adults only average 2-4. Repurposing Longevity Drugs: Dr. Singh's take on Metformin, Rapamycin, and GLP-1s for life extension. The 1:1 Exercise Rule:Why 150 minutes of moderate activity is the threshold for mitochondrial biogenesis. Thank you to our sponsors: BodyHealth - Use the code LYON 20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/ Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts. Chapters: 0:00 - Can You Tell If Your Immune System Is Healthy? 1:37 - Alzheimer's of the Muscle: Muscle-Immune Dysfunction 5:59 - The Thymus Design Flaw: Why Our Immune "Ammo" Disappears 8:44 - Naive CD8 T-Cells: The Elite Forces of Immunity 12:24 - The Axis of Aging: Mitochondria and Immune Cells in Muscle 16:15 - Mitophagy vs. Autophagy: Targeted Cellular Recycling 19:11 - Study Review: Rewiring the Immune System with Urolithin A 24:13 - Mitochondrial Remodeling: Switching from Glucose to Fatty Acids 27:45 - The Trifecta: Gut-Muscle-Immune Axis Connection 31:13 - Parkinson's and the PINK1/Parkin Mitophagy Pathway 35:04 - Clinical Results: Improving Leg Strength in 4 Months 38:51 - Joint Health: Can We Remodel Cartilage with Mitophagy? 43:34 - Targeted Mitophagy Inducers: Exercise vs. Postbiotics 46:44 - Precision Nutrition: The Ideal Muscle Longevity Supplement 53:33 - Why Alzheimer's is Now Considered an Inflammatory Disease 1:00:13 - The Placebo Effect: You Cannot Deceive the Immune System 1:03:13 - Lymphocyte Counts: The Clinical Marker for Immune Aging 1:08:14 - Rapamycin and Metformin: The Future of Longevity Drugs 1:11:42 - Optimal Dosing: Why 1,000mg of Urolithin A is the Standard 1:15:13 - Sports Medicine: Reducing Muscle Damage Markers (Creatine Kinase) 1:20:03 - The Final Frontier: Brain Aging and Selenium Repair Connect with Dr. Anurag Singh Instagram: @timeline_longevity Website: https://www.timeline.comFind Dr. Gabrielle Lyon at: Instagram:@drgabriellelyon TikTok: @drgabriellelyon
Paring Down: Realistic minimalism to live more intentionally
The problem with our determination to declutter in the new year is that we often go hard at the beginning and then burn out fast. Then what? So today I brought on certified life coach and professional organizer, Tracy Hoth, to to discuss practical strategies for overcoming overwhelm, setting realistic expectations, and making real progress in just 15 minute decluttering spurts. Tracy introduces her SPACE method for organizing, and highlights the emotional barriers that can hinder progress. PARING DOWN SOCIALS (SHANNON LEYKO): Instagram: @shannonleyko TikTok: @shannon_leyko Youtube: https://www.youtube.com/@shannonleyko Facebook: www.facebook.com/theexpertbeginner MENTIONED IN THIS EPISODE: Ep 81: The Art of Making Friends & How it Helps Us Declutter TRACY HOTH: Website: https://simplysquaredaway.com/ Tracy's 15 Minute Challenge: simplysquaredaway.com/declutter Tracy's Instagram: @tracyhoth PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode of the Optimal Protein Podcast, I'm joined by Dr. Gabrielle Lyon to break down the muscle-centered strategy every woman needs for fat loss, metabolic health, and long-term strength. We unpack why muscle — not hormones alone — is the key driver of body composition, why midlife fat gain is not inevitable, and how protein intake, movement, and muscle blood flow shape metabolism as women age. Dr. Lyon also explains her much-discussed concept of carb tolerance, how to "earn your carbs," and why excess carbohydrates can quietly work against fat loss when muscle demand is low. Get 20% off the Tone Device to try on a PSMF Day! Shop the collection HERE and use the code VANESSA Dr. Lyon also shares key insights from her new book, The Forever Strong Playbook, including her 24-hour muscle-building framework and why strength training is not optional at any age. If your goals include fat loss, body recomposition, and aging strong, this episode will completely reframe how you think about muscle. Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 20% off the Tone LUX Crystal Red Light Therapy collection including the Crystal Mask and accessories the with the code VANESSA HERE Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Most people don't fail at their goals because they lack discipline — they fail because they were never taught how to set goals that actually work. In this New Year solo episode, Vanessa shares a powerful, step-by-step goal-setting masterclass inspired by Tony Robbins and Brian Tracy, applied specifically to fat loss, body recomposition, strength, energy, and long-term metabolic health. You'll be guided through the actual Tony Robbins Priming Exercise, learn how to set identity-based goals that stick, and discover how to turn motivation into simple, repeatable systems that work even on imperfect weeks. In this episode, you'll learn: Why most health goals fail by February How to set goals from the right nervous system state Tony Robbins' RPM Method applied to body recomposition Brian Tracy's framework for turning goals into daily action How to create motivation-proof plans for fat loss and consistency This episode isn't about perfection — it's about building systems you can repeat all year long.
Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you're following. Joel Greene opens up about the hard lessons he's learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age. Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet tribes—find nutritional flexibility ... 00:21:41 Biomarkers people miss: fasting insulin and acyl carnitines ... 00:23:11 Chronic ketosis, ATP, and metabolic slowdowns ... 00:25:16 Myth-busting muscle and the limits of bodybuilding for aging ... 00:27:17 Functional movement, flexibility, and big toe strength ... 00:34:29 Simple foundation: daily jumps or hops ... 00:47:41 Sensible protocols for muscle gain after 50 ... 01:00:07 Balance in diet as the true key to insulin sensitivity ... 01:08:06 Rules of thumb: meal timing for insulin ... 01:15:56 Stillness, faith, and feeding your spirit ... 01:21:56 Most abused supplement: Antioxidants ... 01:27:54 Body fat percentage as top longevity marker ... 01:29:12 Our Amazing Sponsors: Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial. Blue Peptide Spray from Young Goose - Brings the message back loud and clear. With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Full Show Notes: https://bengreenfieldlife.com/noompodcast/ In this episode, Geoff Cook, CEO of Noom, talks about the science and practicalities of GLP-1 microdosing for weight loss and longevity. He breaks down what microdosing means, how Noom combines low-dose GLP-1 with behavior change programs to promote sustainable results, and the broader health benefits beyond just weight loss—such as improved metabolic markers and reduced inflammation. The conversation also covers safety, affordability, and Noom's new at-home blood testing for tracking progress. Geoff Cook is the CEO of Noom. He is also a serial entrepreneur and long-time public company CEO. He co-founded The Meet Group, a NASDAQ-listed social dating and live-streaming company connecting millions of active users globally. Geoff served as The Meet Group’s CEO from 2013 to 2023, leading it through its sale for $500 million in 2020. Noom Health partners with top health plans and employers to offer a suite of solutions, including Noom Med, Noom Med with SmartRx, Noom Weight, Noom Weight with GLP-1Rx, Noom Diabetes, and Noom Diabetes Prevention Program, to millions. Noom has received multiple National Institute of Health grants and was the first mobile app recognized by the CDC as a certified diabetes prevention program. You can visit Noom and use the code BGNOOM to save 10% off. Episode Sponsors: BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. Their products can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Don’t let another year go by feeling less than your best. Grab 35% off your one month subscription of Mitopure Gummies at Timeline.com/BEN35while the offer lasts. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. Hiya: Give your kids the full-body nourishment they need to grow into healthy adults. I’ve secured a special deal with Hiya on their best-selling children's vitamin—get 50% off your first order today! To claim this deal, you must go to hiyahealth.com/BEN (it is not available on their regular website). Troscriptions: Explore Troscriptions' revolutionary buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade, physician-formulated health optimization compounds directly through your cheek mucosa for faster onset and higher bioavailability than traditional supplements. Discover a completely new way to optimize your health at troscriptions.com/BEN or enter BEN at checkout for 10% off your first order. See omnystudio.com/listener for privacy information.
Paring Down: Realistic minimalism to live more intentionally
This past year brought more change than I expected—personally, spiritually, and professionally. As you'll hear in this episode, some of the change distracted me from pursuing a life free from clutter. So I wanted to share: A) A little recap of my year (some analytic numbers, some personal struggles, etc.) and B) What has helped me recalibrate and reconnect with why decluttering matters in the first place.I hope it motivates you to feel excited about embracing a life that rejects materialism, too! PARING DOWN SOCIALS (SHANNON LEYKO): Instagram: @shannonleyko TikTok: @shannon_leyko Youtube: https://www.youtube.com/@shannonleyko Facebook: www.facebook.com/theexpertbeginner MENTIONED IN THIS EPISODE: Duo Collective marketing podcast & services Episode 19: Decluttering as a Couple with my husband, Aaron Leyko Paring Down Substack Information to Subscribe (weekly blog posts & bi-weekly Decluttering Hype Sessions) PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Learn more about your ad choices. Visit megaphone.fm/adchoices
Dave Rubin of "The Rubin Report" shares the best stories, insights and moments from his sit down interviews of 2025 featuring: Tony Robbins, Peter Thiel, Dr. Phil McGraw, Stephen A. Smith, Jordan Peterson, Bill O'Reilly, Piers Morgan, Douglas Murray, Jason Calacanis, Cheryl Hines, Dr. Mehmet Oz, Scott Galloway, Rob Hersov, David Zucker, Ron DeSantis, Eric Trump, Sage Steele, Eric Weinstein, Bjørn Lomborg, Jillian Michaels, Liz Truss, Tony Abbott, Sen. John Kennedy, Frankie Valli and many more! Watch ALL the FULL INTERVIEWS HERE: https://www.youtube.com/playlist?list=PLEbhOtC9klbBR3q4AO9AdVjeC9r5RyZFP Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ --------- Today's Sponsors: Tax Network USA - If you owe back taxes or have unfiled returns, don't let the government take advantage of you. Whether you owe a few thousand or a few million, they can help you. Call 1(800)-958-1000 for a private, free consultation or Go to: https://tnusa.com/dave Noble Gold Investments - Whether you're looking to roll over an old 401(k) into a Gold IRA or you want physical gold delivered right to your home Noble Gold makes the process simple. Download the free wealth protection kit and open a new qualified account and get a FREE 10-ounce Silver Flag Bar plus a Silver American Eagle Proof Coin. Go to http://DaveRubinGold.com Recharge - The Wellness Company has a way to stay focused, energized, and mentally resilient. This doctor-formulated nutraceutical is the first to combine methylene blue with Urolithin A, creating a unique formula designed to optimize mitochondrial function, improve energy, and elevate cognitive performance. Rubin Report viewers get 15% off plus FREE shipping at checkout when they use code: RUBIN. Go to: https://TWC.health/RUBIN and use CODE: RUBIN
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, I'm continuing our Best of 2025 series with a powerful follow-up to Friday's episode. Instead of an interview, this is a curated masterclass pulling together the most important breakthroughs of 2025 in body recomposition, fat loss, and protein metabolism — especially for women navigating perimenopause and midlife metabolic change. You'll hear standout moments from conversations with Dr. Hannah Cabré, Dr. Arny Ferrando, and Dr. Mike Ormsbee, alongside a solo deep dive into one of the most exciting human randomized controlled trials published in 2025 on high-protein diets, accelerated belly-fat loss, and autophagy. Full Episode with Dr. Hannah Cabré Full Episode with Dr. Arny Ferrando Full Episode with Dr. Mike Ormsbee Full Episode on New Study on Protein Fasting Mimicking and Autophagy/Longevity OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 25% off the Tone Device to try on a PSMF Day! Shop the collection HERE and use the code HOLIDAY25 Get 25% off the Tone LUX Crystal Red Light Therapy collection including the Crystal Mask and accessories the with the code HOLIDAY25 HERE Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Study takeaways start at 18:00 mark Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this special end-of-year solo episode, Vanessa shares a brief personal announcement, followed by the five biggest scientific takeaways from 2025 that reshaped how she thinks about fat loss, longevity, and metabolic health. Tthis episode highlights the studies and expert conversations featured on the Optimal Protein Podcast that had the most meaningful impact this year — including new research on autophagy and protein intake, the real drivers of longevity benefits, menopause-related body composition changes, resistance training, and long-term fat loss maintenance. BOOST YOUR COLLAGEN & ELASTIN with RED LIGHT THERAPY! Save 25% on all Tone Lux Red Light therapy with the code HOLIDAY25! Learn more about the TONE LUX Crystal red light therapy mask and the brand new accessory the TONE LUX CONTOUR for the neck and décollete OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. Vanessa discusses how using the Tone Device is a proxy for fat loss and autophay on Protein Sparing Modified Fasting (PSMF) days!
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode of the Optimal Protein Podcast, Vanessa is joined by Cynthia Thurlow, nurse practitioner, bestselling author, and women's health expert, for a deep dive into why fat loss and muscle maintenance become more challenging during perimenopause and menopause. Cynthia explains how hormonal shifts drive anabolic resistance, reduce blood flow and nutrient delivery to muscle, and accelerate changes in body composition. We discuss how to adapt intermittent fasting for female physiology, why over-fasting can backfire in midlife, and the critical role of protein intake in preserving lean mass. The conversation also explores key insights from Cynthia's upcoming book, The Menopause Gut, including how gut health, inflammation, and hormonal balance are deeply connected—and why optimizing the microbiome can improve metabolic health, body composition, and overall vitality in midlife. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 25% off Tone LUX Crystal Red Light Therapy collection including the Crystal Mask and accessories the at https://ketogenicgirl.com with the code HOLIDAY25 HERE Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Today, I'm joined by Lucas Aoun, from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father's pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking. Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun's journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine's role in motivation and productivity ... 00:32:09 Bioindividual supplement responses and AI in health ... 00:17:00 Alcohol alternatives and social nootropics ... 00:39:52 Optimizing exercise timing and performance ... 00:48:49 Testosterone, thyroid, and men's health fundamentals ... 00:53:01 Diet diversity: carnivore, vegan, and healthy fats ... 00:59:19 Catwaba Pure: origins, benefits, and uses ... 01:13:12 Our Amazing Sponsors: Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off. PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
Paring Down: Realistic minimalism to live more intentionally
When her husband was diagnosed with a terminal brain tumor while she was pregnant with their first child, Andrea Nakayama's career took a hard left turn. Since then, she founded the Functional Nutrition Alliance and has spent the last 20 years helping practitioners and patients learn about a holistic approach to health. In this episode, you'll hear about the importance of both traditional medicine AND functional medicine—and why the term "functional medicine" has been exploited to encourage overconsumption. Together, we explore the state of chronic illness in the U.S., why quick fixes and wellness trends are so seductive, and how the wellness industry often adds more noise than clarity. This conversation is an invitation to declutter our health routines, tune back into our own bodies, and make more intentional, grounded choices—without fear, blame, or overwhelm. ANDREA NAKAYMA: Website: andreanakayama.com Instagram: @andreanakayama Andrea Nakayama Linkedin Article: "You Can't Hack Your Health" PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm Only $2.99 per meal from Every Plate, plus free steak for a month: www.everyplate.com/podcast - CODE: paringsteak Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING Convenient therapy that's covered by insurance: Rula.com/PARING High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Learn more about your ad choices. Visit megaphone.fm/adchoices
Dave Rubin of "The Rubin Report" talks to Sen. Marsha Blackburn about end-of-year battles in Washington and her push to pass the National Defense Authorization Act; how Democrats have used Biden-era Obamacare subsidies to lie to the public about the actual cost of Obamacare how Obamacare subsidies primarily help health insurance company profits; how the Kids' Online Safety Act could truly protect children from Big Tech and social media platforms; why she's running for Tennessee governor; and much more. Check out the NEW RUBIN REPORT MERCH here: https://daverubin.store/ --------- Today's Sponsors: Recharge - The Wellness Company has a way to stay focused, energized, and mentally resilient. This doctor-formulated nutraceutical is the first to combine methylene blue with Urolithin A, creating a unique formula designed to optimize mitochondrial function, improve energy, and elevate cognitive performance. Rubin Report viewers get 15% off plus FREE shipping at checkout when they use code: RUBIN. Go to: https://TWC.health/RUBIN and use CODE: RUBIN
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa What if the real driver of skin aging isn't wrinkles or sun damage — but "zombie" senescent cells hiding in your skin? In this episode of the Optimal Protein Podcast, Vanessa sits down with Dr. Alessandra Zonari, PhD — a stem cell biologist and longevity scientist — for a fascinating deep dive into the new peptide science behind skin aging, inflammation, and biological age. BOOST YOUR COLLAGEN & ELASTIN with RED LIGHT THERAPY! Save 25% on all Tone Lux Red Light therapy with the code HOLIDAY25! Learn more about the TONE LUX Crystal red light therapy mask and the brand new accessory the TONE LUX CONTOUR for the neck and décollete You'll discover: What senescent "zombie" skin cells actually are — and why they don't just age themselves, but affect the surrounding tissue How inflammation in the skin can quietly accelerate collagen breakdown and visible aging Why skin aging speeds up during fat loss, perimenopause, and menopause How scientists are now measuring the biological age of skin, not just how it looks The surprising role of peptides in signaling skin cells to behave more youthfully Why some common "anti-aging" approaches may miss the real drivers of aging What makes lip skin biologically different — and why it tends to age faster than the rest of the face Why nighttime repair, autophagy, and even red light therapy may matter more than you think This conversation goes far beyond skincare routines. It explores the mechanisms of aging at the cellular level, how lifestyle choices influence skin health, and why skin may be one of the most overlooked markers of longevity. If you're interested in skin health, peptides, collagen, inflammation, fat loss, or aging well, this episode will completely change how you think about your skin. Mentioned in this episode: OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. Vanessa discusses how red light therapy supports mitochondrial health, muscle recovery, circulation, and skin health as part of an evidence-based approach to fat loss and metabolic optimization. Explore the Tone LUX red light therapy collection at
Your breath is your most powerful performance tool. In this episode of the Live Long Podcast, part of our Move for Life series, coaches Nate Wilkins and Shebah Carfagna explain how breathwork transforms endurance, strength, mobility and daily resilience.From nasal breathing and diaphragmatic control to rhythm, syncopation and sport-specific techniques, we explore how breathing shapes your workout — and your wellbeing. Learn why beginners often hold their breath under stress, how to build fluid breathing for running, spinning, yoga and Pilates, and how controlled breathing helps you sleep better, calm anxiety and recover faster.If you want to move better and live longer, start with your breath.This is the latest in our 20-part series, Move for Life.You should consult a doctor or qualified fitness professional before beginning a new exercise program, especially if you have an existing health concerns or limited mobility.-----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams. Use the code LLAMA at checkout-EnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountPartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15SiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
Emotional Landscapes: Oscar-Nominated Filmmaker Pen Densham Reinvents Nature Photography The Not Old Better Show, Art of Living Interview Series
Paring Down: Realistic minimalism to live more intentionally
Are you actually prepared for an emergency—or just surrounded by emergency clutter? In this episode, I take a clear-eyed look at emergency supplies and why so many of us over-prepare for rare, dramatic scenarios while under-preparing for the things most likely to happen. We unpack how common cognitive biases—like the availability heuristic, denominator neglect, and “dread risk”—shape our fear-based stocking habits and quietly lead to clutter, overwhelm, and false security. I walk through five realistic categories of emergency preparedness: 1. Evacuation 2. Getting trapped at home 3. Obscure emergencies 4. Everyday sickness 5. First aid and explain how to pare each one down so it's usable, accessible, and actually helpful when stress is high. If emergency prep has ever felt overwhelming—or like another excuse to hold onto too much—this episode will help you rethink what safety really looks like! MENTIONED THIS EPISODE: Ep 76: Is Celebrity Self-Help Advice Useful? with my brother, Jim Oliver Ep 19: Decluttering as a Couple with my husband, Aaron Leyko PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don't just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy' with cellular energy and provides science-supported tools to improve your physical and mental health. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix: https://helixsleep.com/huberman Lingo: https://hellolingo.com/huberman Function: https://functionhealth.com/huberman Waking Up: https://wakingup.com/huberman Timestamps (00:00:00) Martin Picard (00:03:50) What is Energy?, Energy Flow & Transformation (00:07:53) Energy, Vitality, Emotions, Sensory Perception (00:14:18) Sponsors: Helix Sleep & Lingo (00:17:19) “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns (00:25:26) Organelles, Mitochondria & Energy Transformation; Maternal Genes (00:31:12) Mitotypes & Differentiation, Mitochondria as “Social Organisms” (00:36:52) Food & Dysfunctional Energy Transformation (00:40:02) Lifestyle Choices & Interests, Physiological Growth (00:46:39) Pregnancy, Amenorrhea; Illness & Tiredness (00:51:07) Sponsor: AG1 (00:52:29) Energy Transformation & Distribution; Body's Wisdom, Feeling Sick (00:56:27) Tool: Feel Your Energy; Breath & Energy (01:02:31) Flow of Energy; Trade-Offs, Life Purpose & Enjoyment (01:10:15) Biology, Meaningful Experiences & Energy Flow (01:16:27) Sponsor: Function (00:18:15) Inflammation, Energetic Flow (01:20:43) Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging (01:28:56) Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants (01:37:06) Energetic Stress Signals, GDF-15, Cancer, Heart Failure (01:42:18) Genes, Lifestyle & Aging (01:47:54) Gray Hair Reversal, Stress; Inflammation & Aging (01:57:37) Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation (02:05:16) Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep (02:10:58) Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto (02:20:14) Alcohol & Energy Budget; Stress (02:25:02) Exercise, Increase Mitochondria, Overtraining; Resistance & Growth (02:33:06) Sponsor: Waking Up (02:34:41) Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue (02:41:31) Energy Flow & Experiences, Balance (02:49:13) Transform Through Resistance, Energetic Awareness, Connection (02:56:05) Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria (03:01:02) Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation (03:06:10) Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields (03:12:16) Acknowledgements (03:14:15) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa Why do so many people lose weight — only to regain it later? In this episode of The Optimal Protein Podcast, Vanessa Spina sits down with Dr. Holly Wyatt, physician, endocrinologist, and longtime researcher with the National Weight Control Registry (NWCR) — the world's largest and longest-running study of people who have lost weight and kept it off. Building on the audience-favorite episode with Dr. James Hill, this conversation focuses on what the data from over 10,000 successful maintainers actually shows — and why staying in fat-loss mode forever is one of the biggest reasons diets fail. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. In This Episode, You'll Learn: • Why losing weight and keeping it off require completely different skills • The exact reason staying in fat-loss mode too long backfires • What 10,000 successful maintainers had in common • The identity shift that makes maintenance stick • How environment beats willpower every time NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 25% off Tone LUX Crystal Red Light Therapy collection including the Crystal Mask and accessories the at https://ketogenicgirl.com with the code HOLIDAY25 HERE Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Full Show notes: Bengreenfieldlife.com/sleepbetter Michael J. Breus, Ph.D., is a Clinical Psychologist and both a Diplomate of the American Board of Sleep Medicine and a Fellow of The American Academy of Sleep Medicine. He is one of only 168 psychologists in the world to have passed the Sleep Medical Specialty board without going to Medical School. Dr. Breus was recently named the Top Sleep Specialist in California by Reader’s Digest and one of the 10 most influential people in sleep. Dr. Breus is on the clinical advisory board of The Dr. Oz Show and on the show (40 times). Dr Breus pens a monthly column in WebMD magazine, 'Sleep Matters,' and writes regularly for WebMD, The Huffington Post, and Psychology Today. He is also the author of The Sleep Doctor's Diet Plan and Beauty Sleep. Dr. Breus is the author of 4 books, with his newest was released in Dec of 2024 called Sleep, Drink, Breathe: Wellness is too complicated. This book gives an easy-to-follow 3-week program to teach everyone how these 3 simple biobehaviors are the foundation for wellness. He is an expert resource for most major publications, doing more than 300 interviews per year. Visit : bengreenfieldlife.com/orionsleep and use code - GREENFIELD15 to save 15% off Episode Sponsors: Just Thrive: For a limited time, you can save 20% off a 90 day bottle of Just Thrive Probiotic and Just Calm at justthrivehealth.com/ben with promo code: BEN. That’s like getting a month for FREE! Take control today with Just Thrive! The Medicin: Immune Intel AHCC is a clinically studied shiitake mushroom extract that enhances immune cell communication through a patented fermentation process creating highly bioavailable alpha glucans. Backed by 30+ human studies and used in over 1,000 clinics worldwide, AHCC supports immune function for everyday wellness and chronic health challenges—learn more at TheMedicin.com and use code BEN for 10% off. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Go to shop.timeline.com/BEN and use code BEN to get 20% off your order.See omnystudio.com/listener for privacy information.
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa For nearly a decade, many of us have believed that calorie burn eventually plateaus—that once you move enough, your body quietly compensates and stops burning more energy. That belief has shaped how we diet, how we train, and even whether we bother moving more at all. But a brand-new 2025 human study challenges that idea in a way that could completely change how you approach fat loss, daily movement, and exercise. In this Friday recap episode of the Optimal Protein Podcast, Vanessa breaks down the study behind the headlines and explains—in plain English—what the data actually shows, what most people misunderstood, and how to use this information to get better fat-loss results without eating less or training harder. BOOST YOUR COLLAGEN & ELASTIN with RED LIGHT THERAPY! Save 25% on all Tone Lux Red Light therapy with the code HOLIDAY25! Learn more about the TONE LUX Crystal red light therapy mask and the brand new accessory the TONE LUX CONTOUR for the neck and décollete In this episode, you'll discover: Why a new 2025 human study found no true metabolic "cap" in weight-stable, real-world conditions The key detail that separates this research from older metabolism models—and why exercise was misunderstood Why your steps and workouts genuinely increase total daily calorie burn Why muscle—not hormones—is the primary driver of metabolic rate during fat loss Why extreme dieting and "earning food" backfire—and what actually supports sustainable fat loss Study Referenced: Howard et al., 2025, Proceedings of the National Academy of Sciences (PNAS) — Physical activity and total daily energy expenditure in weight-stable adults
Mind–body training is widely recognized as a pillar of healthy aging. Research suggests that how we move — and how we think while we move — are deeply connected. When breath, focus and technique align, we sharpen cognition, reduce stress and build the kind of resilience that keeps us active for life.In this episode of Move for Life, fitness coaches Nate Wilkins and Shebah Carfagna explore why the mind–body connection is more than a trend — it's a practical framework for living longer and living well. From tai chi and yoga to strength training or a simple daily walk, they highlight the unifying theme of intentionality: paying attention to what the body is doing and why.Even small rituals — stepping outside for a dose of “ecotherapy,” or taking a mindful decision-making walk — can transform everyday movement into powerful brain-training moments. Studies now show that moderate physical activity can ease anxiety and depression as effectively as some medications.It's a compelling reminder that exercise isn't just for the body — it's one of the most potent tools we have for lifelong mental well-being.This is the latest in our 20-part series, Move for Life. You should consult a doctor or qualified fitness professional before beginning a new exercise program, especially if you have an existing health concerns or limited mobility.-----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams. Use the code LLAMA at checkout-EnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA PartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
Our understanding of the body's internal clocks is rapidly evolving, with new research shedding light on the powerful effects of circadian rhythms. From the way artificial light disrupts our sleep patterns to how animals' natural cycles offer valuable insights into human health, the science is undeniable. Dr. Philippa Gander, a leading expert in sleep and circadian rhythms and author of Life in Sync: The Science of Internal Clocks and How We're Disrupting Them explains how these disruptions impact not just humans but entire ecosystems, including marine life. Her groundbreaking work also reveals the profound effects of light pollution, offering fresh perspectives on how we can better align our lives with our biological clocks. In this conversation with Peter Bowes, Gander also highlights practical ways we can make adjustments to better sync our lives with nature's rhythms for improved health and well-being.Photo credit: Lucia Zanmonti-----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams. Use the code LLAMA at checkout-Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifyEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA PartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
Paring Down: Realistic minimalism to live more intentionally
In this episode, I sit down with Deedee Moore of More Than Grand to talk about something so many families quietly wrestle with: over-gifting from grandparents. Together, we dig into why it happens, how it feels, and what we can do to bridge the gap with more empathy and clearer communication. Both perspectives matter: The parent perspective (how too many gifts can create stress, clutter, or guilt) AND the grandparent perspective (how giving is often an expression of love, connection, and identity). We explore the sweet intentions behind the gifts, the frustration that can happen on the receiving end, and the simple conversations that can help everyone feel heard. This conversation is full of compassion, aha moments, and practical ideas for strengthening those precious family relationships—without letting “stuff” get in the way. DEEDEE MOORE: https://www.morethangrand.com/ Instagram: @morethangrand Facebook: https://www.facebook.com/morethangrand MENTIONED THIS EPISODE: Free Gift Request Email Template PARING DOWN RESOURCES: Free Decluttering Checklist 10 Life-Changing Decluttering Hacks (free) Treasures of the Heart: A 7-Day Bible Study on Breaking Free from Material Attachments (free) Free 15 Clutter-Free Gift Ideas Free Gift Request Email Template Free Know Your Why Worksheet Complete Guide to Decluttering Kid Stuff SPONSORS: Storyworth Memoirs to capture your loved one's life— get $10+ off: www.storyworth.com/paring 20% OFF any AquaTru water purifier when you go to AquaTru.com and use promo code PARING Convenient therapy that's covered by insurance: Rula.com/PARING 20% off Longevity Mitopure Gummies for Urolithin A at timeline.com/PARING 25% off sitewide plus a $40 bonus gift when you subscribe to Prolon's 5-Day Fasting Mimicking Diet. *remember this is for metabolic health, not simply a weight loss hack*: prolonlife.com/paring Ethical, luxury women's clothing at Quince.com/paring for 365-day returns, plus free shipping on your order! High-quality, eco-friendly activewear at fabletics.com/PARING - sign up as a VIP and get 80% off everything. 10 Free Meals from Hello Fresh: www.hellofresh.com/paring10fm $300 off Air Doctor Pro air purifier: https://airdoctorpro.com/ - Use code PARING Learn more about your ad choices. Visit megaphone.fm/adchoices
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In today's episode, Vanessa sits down with Dr. Howard, the lead author of a brand-new PNAS study that is challenging one of the most widely accepted ideas in human metabolism. For years, many scientists believed that our bodies operate within a fixed daily calorie "budget," and that after a certain point, increasing activity doesn't increase total calorie burn. But Dr. Howard's new research suggests the story may be far more dynamic — and far more empowering — than we ever realized. OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. This conversation explores what this new evidence could mean for: How we think about calorie burn Why activity matters (in ways we didn't fully understand before) The role of fueling, recovery, and energy balance What actually drives fat loss and body recomposition How to train smarter, not harder Mentioned in this episode: Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation — published in Proceedings of the National Academy of Sciences (PNAS). Read the full study here → PNAS DOI 10.1073/pnas.2519626122 NEW! Free High-Protein Keto Guide Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl Get 20% off on the Tone Device breath ketone analyzer or the Tone LUX Crystal Red Light Therapy Mask or the at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Today, I'm giving you a full roadmap of non-hormonal symptom relief, built from research and real-world experience. We'll cover why some women can't or don't take HRT, why some still struggle even when they do, and what tools you can use whether you're hormone-free, hormone-curious, or hormonally supplemented but still not completely supported. Then we'll go symptom by symptom including hot flashes, sleep, anxiety, metabolism, joint pain, GSM and map out what actually works. We Cover: • Why some women avoid HRT and why others still need more support. • The foundations every woman needs, with or without hormones. • Non-hormonal solutions for hot flashes, night sweats, anxiety, irritability, sleep, mood, metabolism, muscle loss, cognitive decline, weight gain, fatigue and GSM. • What to know about supplement safety and phytoestrogens. RESOURCES Recommended Items + Discounts: Karen Martel: https://podcasts.apple.com/us/podcast/non-hormonal-solutions-to-peri-and-post-menopausal/id1438772276?i=1000682224707 Herbal Medicine in Menopause: Myths, Mistakes, & Must-Haves with Sara Chana Silverstein Master Herbalist: https://podcasts.apple.com/us/podcast/herbal-medicine-in-menopause-myths-mistakes-must-haves/id1531105768?i=1000727879524 Discount Codes PDF: Osteoarthritis episode: https://youtu.be/b7aTb7cHn7o?si=WDVXmO3HwHruhXmm PRP episode: https://podcasts.apple.com/us/podcast/stop-arthritis-prevent-degeneration-in-joints-alternatives/id1531105768?i=1000523184934 https://drive.google.com/file/d/110eG0zBhHwpWS6_BVgj1RtL-JmKgqgmL/view?usp=sharing Urolithin A: https://youtu.be/OsaWrkM3Fxs?si=SeZ-nTuf46H2o4QO Methylene Blue: https://youtu.be/XHhMN3oC69M?si=B5pCINSXA19rNcQs BFR guide: https://drive.google.com/file/d/1dSwrG6u737O5o7_TOd3PkRfeGsz8ESX5/view?usp=drive_link Hot Flash Program: https://hackmyage.com/hot-flash-masterclass/ Energy Reboot Program: https://hackmyage.com/energy-reboot-self-guided/ Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here - https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA here - http://oxfordhealthspan.com/discount/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com - https://trysuji.com Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050 Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: @Hack My Age Facebook Group: @Biohacking Menopause Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: @HackMyAge Website: HackMyAge.com For partnership inquiries: https://www.category3.ca/ Some episodes of Hack My Age are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.
If you moved into a house and you're finding chronic symptoms surfacing - chronic coughing, phlegm and trouble breathing - you could be dealing with sneaky, hidden mold. This episode breaks down what you can do from a holistic health perspective. Doctor Motley's Recommendations: ------ Testing for mold toxins: Mycotoxin testing, OATS (Organic Acid Test) - https://mosaicdx.com/ Immunolytics - https://immunolytics.com/ As you remove yourself from mold, you want to make sure you're having proper bowel movements. If you're struggling in this area, colonics or coffee enemas are good options to explore (if you have leaky-gut type symptoms, take some bone-broth, L-glutamine and butyric acid). If you're blocked up, try magnesium oxide, Dr. Scholze's intestinal formula (https://www.herbdoc.com/intestinal-formula-1). Toxins like mold can weaken our immune systems, leaving us more susceptible to parasites. If this is you, give Kim Rogers' Parafy kit a whirl. You can get 10% off here: https://shorturl.at/Gjpg5 Herbs that specifically help with mold Morinda Supreme: https://shorturl.at/AmP3p Smilax Supreme: https://shorturl.at/yTH9J Binders like Bentonyte Clay or Charcoal Scutallaria - Clears heat-toxin and inflammation, supports the Liver, and calms overactive immune responses: https://tinyurl.com/3a8rhs75 Milk Thistle for Liver Support Uva Ursi for Kidney Support: https://tinyurl.com/2s3upajb Homeopathics: DesBio - Mold/SSR https://dbscript.com/product/moldssr/ Find a Building Biologist near you: https://url-shortener.me/1P1N ------ Follow Doctor Motley Instagram TikTok Facebook Website ------ *If you're a health coach looking to advise parents and families, or even if you're a hardcore health nerd who wants to dive deeper and take advantage of ALL Doctor Motley's clinical experience, he has a membership to help you get the most out of your health and help the people you love. If you'd like to poke around for free for 15 days, check out https://www.doctormotley.com/15 *Learn more about Urolithin A supplementation (in sugar-free gummy form) at Timeline.com/DRMOTLEYGUMMIES and use promo code DRMOTLEY for 20% off with your first purchase!
In today's episode, Vanessa reveals the shocking new human research on two of the most powerful and science-backed supplements for women's fat loss, muscle tone, metabolic health, skin rejuvenation, and longevity: creatine and collagen. You'll discover why creatine is no longer just a gym supplement, and how groundbreaking new data shows collagen may actually influence biological age. This episode is packed with cutting-edge insights every woman needs to hear. Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa In this episode, you'll learn: ✨ The shocking results from new human studies on creatine and collagen ✨ Why creatine is one of the most underrated supplements for women, especially in perimenopause and post-menopause ✨ How creatine enhances fat loss, muscle tone, metabolic rate, cognition, and sleep-deprivation resilience ✨ The simple, evidence-based dose of creatine that works for women — and why Vanessa uses Puori creatine ✨ The brand new 2025 human trial showing collagen's key amino acids reduced biological age by an average of 1.4 years ✨ How collagen improves skin elasticity, hydration, wrinkles, nails, hair, joints, and connective tissue strength ✨ Why stacking creatine + collagen is a powerful strategy for fat loss, lean muscle retention, skin health, and healthy aging If you want a clear, science-backed guide to creatine and collagen — including exactly how to dose and use them for optimal results — this episode is for you.
Farmers' walks - carrying weight in each hand and moving with steady control - are catching on as a simple, full-body exercise that mirrors real life. In this episode Ageless Workout creators Nate Wilkins and Shebah Carfagna, explain why this straightforward movement does far more than build strength. It boosts grip power - a marker often linked with overall health and longevity - and helps improve posture, core stability, and balance. Switch to a single side carry and you add a strong anti-tilt challenge that wakes up the entire midsection.From staying ready for travel to handling everyday tasks with confidence, the farmers' walk reflects the kind of movement that supports aging well. This is the latest in our 20-part series, Move for Life. You should consult your healthcare providers before starting or modifying a fitness routine.You should consult a doctor or qualified fitness professional before beginning a new exercise program, especially if you have an existing health concerns or limited mobility.-----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams. Use the code LLAMA at checkout-EnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA PartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
Today, I'm joined by the innovative Jon Hacker, whose name couldn't be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it? Use code NAT at https://zenbud.health/nat for 20% off Episode Timestamps: Introduction to Longevity Podcast and Host ... 00:00:00 The Rise of Anxiety and Mental Health Innovation ... 00:05:19 Why Modern Society Fuels Anxiety ... 00:07:18 Impact of Chronic Stress on Health ... 00:08:51 Barriers to Managing Anxiety with Habits Alone ... 00:17:17 CBT and the Need for Better Tools ... 00:19:27 Vagus Nerve: What It Does and Why It Matters ... 00:20:37 Zenbud: Ultrasound vs. Electrical Stimulation ... 00:28:58 Zenbud Headset Experience and Simplicity ... 00:34:25 Zenbud's Role in Stress Resilience and Longevity ... 00:47:45 Purpose, Mindfulness, and the Future of Biohacking ... 00:50:55 Zenbud: Key Safety Points and Adoption Challenges ... 01:01:08 Zenbud as "An Off Switch for Stress" and Closing ... 01:02:52 Final Tips, Special Offer, and Outro ... 01:03:30 Our Amazing Sponsors: Sunlamp (BTS2) by Mitolux - When your skin makes vitamin D from UVB light, it also creates natural companion molecules that help your body use it smarter—so you're not just boosting levels, you're activating your biology the way nature intended. Visit mitolux.com/NAT10. You'll receive 10% off! NAT10 will be automatically applied at checkout. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Probiotic Breakthrough by Bioptimizers - uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
The ALL ME® Podcast Do You Need URO-A and CoQ-10 In Your Life? – Dr. Emily Werner In this episode of the ALL ME Podcast, Don Hooton speaks with Dr. Emily Werner, a sports dietitian for the Philadelphia 76ers. They discuss Dr. Werner's journey into sports nutrition, her experiences working with professional athletes, and the importance of building relationships with players to effectively communicate nutritional advice. The conversation also covers the role of nutrition in enhancing athletic performance, the collaboration with external nutrition professionals, and the significance of specific nutrients like Urolithin A in supporting athletes' health and performance. In this conversation, Dr. Emily Werner discusses the significance of gut health, the role of Urolithin A and CoQ10 as supplements, and the importance of dietary choices in maintaining optimal health. She emphasizes the need for targeted supplementation due to the decline in gut microbiome diversity and the natural production of CoQ10 with age. The discussion also highlights the role of dietitians in assessing nutritional deficiencies through blood work, particularly in athletes, and the evolving landscape of dietary supplements. To Purchase urolithin A in supplement form, Emily recommends purchasing from www.timeline.com Takeaways Dr. Werner's journey into sports nutrition began with a love for anatomy and physiology. Building relationships with athletes is crucial for effective nutrition counseling. Nutrition plays a vital role in the performance and longevity of athletes. Urolithin A is a metabolite that supports mitochondrial health. Athletes often have their own chefs or nutritionists, complicating team dynamics. Effective communication with external nutrition professionals is essential. Traveling with the team allows for better food coordination and athlete support. Nutrition education is important for young athletes to enhance their performance. The importance of nutrition has grown in professional sports over the years. Athletes benefit from a diet rich in fruits, nuts, and other nutrient-dense foods. Not everyone has the right gut microbiome for nutrient conversion. Urolithin A is a supplement that addresses bioavailability issues. Foundational supplements like Urolithin A can benefit everyone. CoQ10 is essential for energy production in mitochondria. CoQ10 helps clear out reactive oxygen species in the body. Urolithin A and CoQ10 can work synergistically for health. Dietary sources of CoQ10 include meat and fish. Statins can deplete natural CoQ10 levels in the body. Blood work can reveal nutritional deficiencies in athletes. Dietitians play a crucial role in nutritional health and prevention. Chapters 00:00 Introduction to Sports Nutrition and Dietetics 02:59 Dr. Emily Werner's Journey to Sports Dietetics 06:03 Working with Professional Athletes 09:01 Collaboration with External Nutrition Professionals 11:57 Traveling with the Team and Food Coordination 14:54 The Importance of Nutrition in Professional Sports 16:10 Understanding Urolithin A and Its Benefits 21:54 The Importance of Gut Health and Urolithin A 25:39 Urolithin A: A Foundational Supplement 26:09 Understanding CoQ10 and Its Role 30:15 CoQ10: Food Sources and Supplementation 32:55 Blood Work and Nutritional Deficiencies 34:18 The Role of Dietitians in Athlete Health 35:55 Curveball Round: Fun Questions with Dr. Werner Contact Emily: Instagram: @emilywerner34 LinkedIn: https://www.linkedin.com/in/emily-n-werner-phd-rd-cssd-ifncp-4a820a97/ Follow Us: Twitter: @theTHF Instagram: @theTHF Facebook: Taylor Hooton Foundation #ALLMEPEDFREE Contact Us: Twitter: @theTHF Instagram: @theTHF Facebook: Taylor Hooton Foundation #ALLMEPEDFREE Email: info@taylorhooton.org Phone: 214-449-1990 ALL ME Assembly Programs: http://taylorhooton.org/education-resources/face-to-face-programs/
If you're heading into the holidays feeling drained or unfocused, this episode is your reset button. Before the year ends, I'm sharing my personal health gift guide—the real tools and rituals I use to support my brain, boost my energy, and improve my sleep. I walk you through the five pillars I rely on: mitochondrial support circadian rhythm, environment and light hygiene lymphatic drainage for clearer thinking sleep optimization blood work From red light therapy and blue-light–blocking tools to electrolytes, creatine, nontoxic cookware, and the blood work I swear by—these are the science-backed wellness picks I'm gifting to myself and the people I love. Let's head into the new year feeling stronger, clearer, and truly supported. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Boncharge: Red Light Face Mask for 25% off sitewide - no code needed. Head to https://boncharge.com/products/red-light-face-mask?rfsn=8835559.ace3e64 Time-line: Save 30% on your Longevity Routine today! This sale ends 12/1 so head to https://www.timeline.com/promotions/bfcm-nutrition?utm_source=neuroexperience&utm_medium=Newsletter&utm_campaign=BFCM&utm_term=TOF&utm_content=Nutrition for 30% off. *** Products mentioned: Brain Code: https://go.neuroathletics.com.au/brain-code Urolithin a: https://www.timeline.com/partners/neuro-athletics Happy Light: https://a.co/d/ePBIExx Boncharge light bulbs: https://boncharge.com/products/full-spectrum-light-bulb Boncharge blue light blocking glasses: Boncharge Blue Light Blocking glasses Boncharge red light panel: https://boncharge.com/products/demi-red-light-device EightSleep: https://www.eightsleep.com/product/pod-cover/ Supplements: Myo-inositol L-theanine GABA Magnesium L-threonate Vibration plate: https://a.co/d/gBsVZ0Z Hyperice Normatec Boots: https://hyperice.com/products/normatec-3-legs/ Creatine: https://puori.com/neuro Cookware: https://Carawayhome.com/neuro Blood work: https://functionhealth.com/louisa I'm Louisa Nicola — clinical neurophysiologist — Alzheimer's prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer's risk — and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Holiday Message & Why Brain Span Matters 01:44 – The Five Pillars of My Wellness Rituals 03:23 – Mitochondrial Health 101 (Foundational Tools) 05:09 – Urolithin A & How I Support Mitochondria 07:44 – Light, Circadian Rhythm & Brain Performance 09:34 – My Night Ritual: Melatonin & Blue Light Blocking 13:25 – Why I Use Red Light & Infrared Therapy Daily 15:41 – Sleep Rituals for Deep Recovery 17:52 – Lymphatic Drainage for Brain Fog & Alzheimer's Risk 19:45 – Creatine for Energy & Sleep Deprivation Support 20:47 – Micro Habits: Hydration, Breathwork & Training 22:52 – Non-Toxic Cooking: Why I Switched to Caraway 23:35 – Bloodwork Every Four Months (My #1 Health Gift) 24:07 – Final Thoughts & Holiday Wishes Learn more about your ad choices. Visit megaphone.fm/adchoices
This episod is brought to you by Cured Nutrition, Caldera Lab and Joi & Blokes. Dr. Jessica Shepherd—OB/GYN, clinical advisor for P-Volv, and author of Generation M—breaks down everything women need to know about perimenopause, menopause, and longevity. She explains why mindset is the foundation of midlife health, how declining estrogen affects every organ system, why only 8% of symptomatic women ever receive a diagnosis, and how common comorbidities rise 45% or more between ages 40–59. Dr. Shepherd shares science-backed strategies for navigating symptoms, improving metabolic and mitochondrial health, understanding the truth about hormone therapy after the flawed WHI study (which led to an 82% decline in prescriptions), and using exercise, protein, and muscle-building to protect cognition, heart health, and overall vitality. Whether you're a woman entering midlife—or a partner wanting to better support her—this conversation is a masterclass in women's health, empowerment, and aging well. Follow Jessica @jessicashepherdmd Follow Chase @chase_chewning ----- 00:01 - Intro & shocking stats: women live longer but spend more years in poor health; HRT prescriptions dropped 82% after 2002 00:28 - Muscle as the organ of longevity; women lose 3–5% per decade, accelerated after menopause 01:18 - Why estrogen decline shifts the whole body; Dr. Shepherd introduces herself and her mission in women's health 02:15 - Redefining women's health & longevity; why women aren't thinking about longevity soon enough 04:23 – Mindset, habits, and community as the foundation of midlife health 07:13 - Barriers to staying well: socioeconomic factors, upbringing, access, and misconceptions about wellness 09:33 - Women's current wellness landscape; societal expectations, caregiving burden, and systemic gaps 12:46 – Major healthcare gaps: lack of research, exclusion of women from clinical studies until the '70s, and only 3% of VC health funding going to women 17:30 – Pharma eliminating women's health divisions; downstream effects on innovation and access 19:10 – Perimenopause 101: defining terms, symptoms vs. cycles, 34+ possible symptoms, and why diagnosis is trick 24:45 – The cardiovascular danger of estrogen decline; heart disease as the #1 killer of women 27:02 – Stress vs. perimenopause symptoms; mood disorders peak between 45–55 29:48 – How HRT has evolved in the last 10–20 years; symptom relief and longevity benefits 32:32 – Why only 5% of women are on hormone therapy today; misconceptions and new guidelines 34:20 – WHI study deep dive: media panic, misinterpretation, lack of statistical significance, and lasting fear 39:06 – Risk vs. benefit: how to think about HRT decisions with your provider 41:51 – Chase shares his TRT story; quality of life, fertility considerations, and hormone literacy 45:16 – Dr. Shepherd's personal hormone story: cognition issues, testosterone, and starting estrogen at 46 48:12 – Supplements Dr. Shepherd uses: Vitamin D, creatine, CoQ10, Urolithin A 50:10 – Muscle, mitochondrial health, sarcopenia & glucose control: why resistance training is non-negotiable 52:25 – Movement, neuroplasticity, balance & cognition: why staying active protects the aging brain 55:12 – How partners can best support women in perimenopause: emotional support & shared routines 57:52 – The science of emotional support: social connection decreases pain, inflammation, and improves outcomes 59:22 – Menopause explained: average age, symptom timeline, and the hidden cellular changes 01:02:39 – Nutrition, glucose control, protein needs, alcohol & sugar intake, and metabolic health 01:07:07 – Protein requirements (1.0–1.2g/kg), resistance training, and why women must build muscle 01:09:37 – U.S. data: 55%+ of women report symptoms; only 8% diagnosed; why doctors miss it 01:12:34 – Which providers are best for menopause care & what certifications to look for 01:15:31 – Comorbidities rise 45% between 40–59: hypertension, thyroid, arthritis, sleep disorders & estrogen's role 01:18:25 – Is biohacking menopause possible? Current limits + ovarian longevity research 01:22:24 – Exercise as the ultimate biohack; sustainable movement for aging wel 01:23:19 – Final Q: How Dr. Shepherd lives Ever Forward — flexibility, pause, and growth ----- Episode resources: 20% off DREAM gummies with code EVERFORWARD at CuredNutrition.com/everforward 50% off any product or diagnostic labs with code CHASE at JoiAndBlokes.com/chase 20% off any men's skincare product with code EVERFORWARD at CalderaLab.com Watch and subscribe on YouTube
Full Shownotes: https://bengreenfieldlife.com/rootcause Morley Robbins is the creator and founder of The Root Cause Protocol and the Magnesium Advocacy Group. Morley received his BA in Biology from Denison University in Ohio and holds an MBA from George Washington University in healthcare administration. Morley has trained in wellness coaching, nutritional counselling, and functional diagnostic nutrition. He is also known as the Magnesium Man due to his extensive research into and understanding of magnesium’s role in the body. Morley’s research saw him deciphering the intricate relationship between magnesium, iron, copper, and calcium as a way to free ourselves from illness and dis-ease. As a certified health coach with an expertise in Hair Tissue Mineral Analysis (HTMA), Morley has performed thousands of RCP one-on-one consultations, helping people feel better by getting to the root cause of their symptoms. The Root Cause Protocol (RCP) we discuss in this podcast was developed by Morley, who transformed a career in the mainstream medical industry into a quest to learn the fundamental components of a healthy metabolism. The RCP claims to work by restoring balance to the key minerals – magnesium, copper and iron – that must work together in order to optimize energy and increase vitality. Now, the RCP is in Morley‘s new book “Cure Your Fatigue” This book is designed for those seeking the truth in human metabolism and those wanting to take back control of their health. It is one part textbook and one part user's guide based on a decade of research and client experience Episode Sponsors: Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. Pique: Pique Teas is where plants and science intersect to produce teas and supplements of unrivaled efficacy, purity, and convenience. Go to Piquelife.com/Ben to get 20% off for life, plus a free starter kit with a rechargeable frother and glass beaker to elevate your ritual. LeelaQ: Not only do LeelaQ’s products neutralize EMFs, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com and use code BEN10 for 10% off. Timeline Nutrition: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Go to shop.timeline.com/BEN and use code BEN to get 20% off your order. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. Their products can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD to save 25% off for a limited time.See omnystudio.com/listener for privacy information.
Upgrade your biology in 10 minutes with this week's rundown from Dave Asprey. This episode breaks down the six biggest stories in biohacking and health tech, from sleep hormones to mitochondrial rejuvenation, giving you the data you need to live longer, think faster, and perform at your peak. This episode covers: • The Melatonin Heart Warning Everyone Missed A major new study from the American Heart Association reveals that long-term melatonin users face nearly twice the risk of heart failure and 3.5 times higher hospitalization rates. Once considered a harmless sleep aid, melatonin's hormonal effects may disrupt cardiovascular recovery, testosterone, and blood pressure regulation when used nightly. The takeaway: melatonin is a short-term circadian reset tool, not a forever supplement. Source: American Heart Association — newsroom.heart.org/news/long-term-use-of-melatonin-supplements-to-support-sleep-may-have-negative-health-effects • Bryan Johnson's Extreme Microplastics Detox Biohacker Bryan Johnson shared lab-verified results showing an 85% reduction in microplastics in his semen after one year of daily 200°F dry saunas followed by ice packs on the groin. It's not peer reviewed yet, but it'ssparking global discussion about environmental toxins, fertility, and detoxification. Whether or not you follow his protocol, this study highlights how widespread microplastics have become and how heat, sweat, and smarter exposure control may help fight back. Source: New York Post — nypost.com/2025/10/23/health/biohacker-bryan-johnson-got-rid-of-85-of-microplastics-from-his-semen • Urolithin A: The Mitochondrial Molecule That Strengthens Immunity A peer-reviewed human trial published in Nature Aging found that four weeks of daily Urolithin A (Mitopure®) supplementation improved immune function in adults aged 45–70, increasing youthful CD8 T-cells, natural killer cells, and mitochondrial performance inside immune cells. By triggering mitophagy, your body's cleanup process for old mitochondria, Urolithin A enhances energy, resilience, and immune strength. It's the clearest evidence yet that we can modulate immune aging through mitochondrial renewal. Head to timeline.com/dave to get 10% off your first order. Source: BioSpace — biospace.com/press-releases/timeline-continues-to-build-the-most-clinically-researched-longevity-products-targeting-immune-brain-and-muscle-aging • Google's New AI Model That “Talks” to Cells Google DeepMind and Yale launched Cell2Sentence-Scale, an open-source AI model that lets scientists query cellular pathways in natural language. The system can predict how cells transition from healthy to cancerous states and identify molecular switches that might reverse those changes. It's compressing years of biology into days and democratizing research for small labs and independent scientists alike. Isn't AI a beautiful thing? Source: Google DeepMind — blog.google/technology/ai/google-gemma-ai-cancer-therapy-discovery • Omega-3s Calm the Brain and the Temper A massive new meta-analysis of randomized controlled trials shows omega-3 fatty acids (EPA and DHA) reduce aggression by up to 28%. That includes both reactive anger and planned aggression. By lowering neuroinflammation and stabilizing cell membranes, omega-3s appear to balance dopamine and serotonin, proving that healthy fats aren't just heart food, they're emotional regulators too. Source: Science Alert — sciencealert.com/one-dietary-supplement-was-shown-to-reduce-aggression-by-up-to-28 • Chronic Fatigue Syndrome Finally Gets a Biomarker For the first time, researchers have developed a blood test that accurately identifies chronic fatigue syndrome (ME/CFS) using DNA methylation and micro-RNA expression patterns. This breakthrough distinguishes CFS from other autoimmune and viral conditions, marking a turning point for millions of patients long dismissed by traditional medicine. It's proof that data-driven diagnostics can transform how we understand mystery illnesses. Source: Science Daily — sciencedaily.com/releases/2025/11/251102205021.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: melatonin heart risk, sleep hormones, microplastics detox, Bryan Johnson, Urolithin A, mitophagy, mitochondrial health, immune aging, DeepMind AI, cellular modeling, omega-3 aggression, neuroinflammation, chronic fatigue biomarker, ME/CFS test, biohacking news, longevity research Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser.-Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:18 — Story 1: Melatonin & Heart Health 1:58 — Story 2: Microplastics Detox 3:39 — Story 3: Urolithin A & Immune Function 5:19 — Story 4: AI Cell Model 6:57 — Story 5: Omega-3 & Aggression 8:43 — Story 6: CFS Blood Test 9:59 — Weekly Upgrade Protocol See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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