Pharmacy Focus

Find out more information about the Psychedelic Pharmacists Foundation (PPF) & Psychedelic Pharmacists Association (PPA):PPF: https://www.psychedelicpharmacistsfoundation.org/PPA: https://psychedelicpharmacist.org/

The discussion examines the evidence behind common concerns about everyday products, food trends, and lifestyle habits, while emphasizing a practical, individualized approach to health and cancer prevention.

A panel of clinical pharmacists meets to discuss the complex process of operationalizing cell and gene therapy at an academic medical center.

In this episode of Mind the Meds, Erica Marini, PharmD, highlights information from the European Stroke Organization Conference include encouraging data on asundexian(Bayer), a factor XIa inhibitor showing reduced recurrent ischemic stroke risk without increased bleeding, as well as positive results from three trials of tirofiban in acute ischemic stroke settings. On the multiple sclerosis (MS) front, Marini covers the FDA approval of ocrelizumab (Ocrevus; Genentech) for pediatric relapsing-remitting MS in children 10 and older, a new study supporting early use of high-efficacy agents in pediatric MS, and 2 Lancet publications on ocrelizumab — one examining higher weight-adjusted dosing (which did not improve disability progression) and one confirming benefit in a broader primary progressive MS population. She also briefly discusses PADOVA (NCT04777331), a phase 2b trial of prasinezumab in early Parkinson's disease, which failed to meet its primary end point.The bulk of the episode is a discussion with guest Millad Sobhanian, PharmD, BCPS, clinical pharmacy specialist in neurology at the University of Maryland, focused on Alzheimer disease. They cover dextromethorphan/bupropion (Auvelity; Axsome Therapeutics), newly approved in April 2026 for agitation associated with Alzheimer dementia. Sobhanian walks through key safety considerations—including additive NMDA antagonism if combined with memantine, cardiovascular risks from the bupropion component, and the ever-present black box warning on antipsychotics in dementia patients—while both note that the efficacy data, though statistically significant, shows modest clinical effect sizes compared to the threshold for meaningful within-patient change.The conversation then turns to lecanemab's subcutaneous initiation formulation (Leqembi Iqlik; Eisai, Biogen), whose FDA decision has been delayed to about August 2026 as regulators seek more data on bioavailability and ARIA monitoring in the at-home setting. Sobhanian shares his real-world perspective on anti-amyloid therapy, describing a patient population that is typically early-stage, high-functioning, and has a mean age of about 60 to 70 years, and emphasizing the pharmacist's role in expectation-setting around the modest but potentially cumulative slowing of cognitive decline. The episode closes with a thorough discussion of the April 2026 Cochrane review on amyloid-targeting monoclonal antibodies, which both Marini and Sobhanian find overly broad in its conclusions. They note limitations such as the inclusion of withdrawn agents like aducanumab (Aduhelm; Biogen), heterogeneous inclusion criteria across trials, and an 18-month study horizon that may be too short to capture the full benefit suggested by longer-term open-label extension data.Key Takeaways:1. New options for Alzheimer's agitation exist, but fit carefully into the treatment algorithm. Dextromethorphan/bupropion offers a novel NMDA-based mechanism for treating agitation in Alzheimer dementia, but its clinical effect size is modest, and it carries meaningful safety considerations—particularly around the bupropion component in elderly patients. Like all pharmacologic options in this space, it remains a later-line choice after nonpharmacologic interventions have been exhausted, and medication reconciliation is critical given its interaction potential with memantine and CYP2D6 inhibitors.2. Anti-amyloid therapies are imperfect but not ready to be written off. The April 2026 Cochrane review drew significant attention with its conclusion that anti-amyloid monoclonal antibodies produce only trivial cognitive benefits, but its findings are limited by the inclusion of older, withdrawn agents, heterogeneous trial populations, and an 18-month time horizon that may be too short to capture the full trajectory of benefit.3. The pharmacist's role in anti-amyloid therapy goes well beyond dispensing. As illustrated by Sobhanian's practice at the University of Maryland, clinical pharmacists embedded in neurology clinics play a critical role in patient selection, expectation-setting, ARIA counseling, and informed decision-making for patients considering anti-amyloid therapy—a complex, high-stakes treatment decision that these patients and their caregivers should never be navigating alone.

In this episode of Pharmacy Focus, moderator Bob Haight, PharmD, BCPP, AAPP Annual Meeting director and past president of American Association of Psychiatric Pharmacists (AAPP), discusses the AAPP 2026 Annual Meeting with Archana Jhawar, PharmD, BCPP, clinical assistant professor at the University of Illinois Chicago; and Chelsea Di Polito, PharmD, BCPP, psychiatric clinical pharmacist at the University of Maryland, Baltimore. The discussion centers on emerging trends in psychiatric pharmacotherapy across diverse practice settings. A major focus is on newer psychiatric medications, including sublingual dexmedetomidine for acute agitation, which offers a novel, patient-friendly administration route and potential benefits for inpatient care. Additional discussion covers agents like lumateperone and xanomeline-trospium, with attention to their safety profiles, tolerability, and evolving roles in treatment. The speakers emphasize the importance of real-world experience in determining how these newer therapies fit into clinical decision-making, especially given considerations like cost, monitoring requirements, and patient-specific factors.The episode also explores cutting-edge research and practice challenges, including the growing interest in GLP-1 receptor agonists for substance use disorders. While still considered “unproven but promising,” early data suggest these agents may reduce addictive behaviors by modulating reward pathways rather than through traditional metabolic effects. Additional highlights include evolving strategies for clozapine monitoring following REMS changes, where pharmacists play a central role in balancing safety and access, and advancements in long-acting injectable antipsychotics that improve flexibility, adherence, and patient-centered care. Across all topics, a consistent theme emerges: the expanding range of treatment options requires clinicians to stay informed, adaptable, and focused on individualized care. The speakers conclude that AAPP's annual meeting provides a valuable forum for translating emerging evidence into practical strategies that can be immediately applied in clinical practice.Read more about the AAPP here: https://aapp.org/ed/meeting/2026Additional information on the AAPP Annual meeting can be found here: https://aapp.org/ Key Takeaways: New psychiatric treatments are expanding options but require real-world context. Emerging therapies—such as sublingual dexmedetomidine, lumateperone, and xanomeline-trospium—offer novel mechanisms, improved tolerability, and alternative administration routes. However, clinicians are still determining where these agents fit in practice, making shared clinical experience and practical insights critical for informed use. Innovative research is reshaping how clinicians think about psychiatric and substance use treatment. GLP-1 receptor agonists are gaining attention for substance use disorders, with early evidence suggesting they may reduce addictive behaviors by acting on reward pathways. While still investigational, this highlights a broader shift toward targeting underlying neurobiology rather than just symptoms. Pharmacists play a central role in navigating evolving care models and improving patient outcomes. From optimizing clozapine monitoring after REMS changes to implementing long-acting injectable antipsychotics, pharmacists are key in balancing safety, access, adherence, and education. Their involvement is essential as treatment options become more complex and patient-centered.

You can connect with Marilyn Bulloch on LinkedIn here.Read more insights about hepatitis B throughout Hepatitis Awareness Month at Pharmacy Times' Hepatitis Resource Center.Episode Timestamps:1:05: Introduction2:08: Current Disease Burden of Hepatitis B3:55: Risk Landscape for Adults7:20: Link Between Chronic Hepatitis B and Liver Cancer10:25: Expanded Vaccine Recommendations13:25: The Role of Pharmacists in Vaccine Counseling16:40: Why Shorter Conversations Are Better17:55: Advantages of 2-Dose Schedule20:40: Closing the Adult Hepatitis B Immunization Gap23:50: A Patient Counseling Scenario25:25: Closing Thoughts

When a cancer patient says "I've been doing some research," the conversation that follows can be just as complex as the treatment itself. In this episode, a malignant hematology clinical pharmacy specialist joins us to unpack health misinformation, AI-generated medical advice, wellness culture, and the controversial therapies oncology patients are bringing into the clinic — and how pharmacists can navigate it all.

This inaugural episode of Mind the Meds introduces neurology pharmacy practice through a discussion between 3 neurology pharmacists working across inpatient and outpatient settings at the University of Utah. Host Erica Marini, PharmD, meets with her colleagues, Sarah Dahoney, PharmD, and Tyler Kenny, PharmD, BCCCP, both of whom are clinical pharmacists at the University of Utah Health, to discuss the research presented at the 2026 American Academy of Neurology (AAN) Annual Meeting. After sharing their diverse professional “origin stories,” the conversation then shifts to the role of pharmacists in neurology care and highlights key updates from the American Academy of Neurology annual meeting. The hosts discuss advances in neuromuscular disease, particularly myasthenia gravis, where emerging therapies such as FcRn inhibitors and CAR T-cell therapies are reshaping treatment paradigms. They also explore rare neurological conditions like stiff person syndrome and Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), where early-phase trials suggest promising but still preliminary therapeutic options. Finally, the episode reviews broader neurologic and systemic trends, including GLP-1 receptor agonists and SGLT2 inhibitors, noting potential but not yet definitive benefits in dementia prevention, stroke risk reduction, and migraine outcomes. Across all topics, the episode emphasizes the rapid evolution of neurological therapeutics and the expanding role of pharmacists in maneuvering complex, high-cost, and highly specialized treatments.Key Takeaways: Neurology pharmacy is highly collaborative and evolving, with non-linear career pathways. Pharmacists in neurology often enter the field through diverse experiences rather than a standardized training pipeline, and success depends heavily on adaptability, clinical curiosity, and initiative.  Pharmacists play a critical role in optimizing complex neurological therapies and care transitions. Their contributions span inpatient safety monitoring, outpatient medication access and affordability support, and ensuring continuity of care for high-risk, high-cost therapies.  Neurology therapeutics are rapidly advancing, but many emerging treatments remain early-stage. New therapies such as FcRn inhibitors, CAR T-cell approaches, and complement-targeting agents show promise across conditions like myasthenia gravis and rare neuroimmunologic diseases, while broader drug classes like GLP-1s are still under investigation for neurological benefits. 

Dr. JAM can be found on LinkedIn.Stay tuned for Pharmacy Times' coverage of APhA 2026 in LA. It can all be found here.

You can find more information about Derek Webb, PharmD, and Dennis Williams, PharmD, BCPS, AEC, below:Derek Webb on LinkedInDennis Williams on LinkedInDennis Williams Faculty Page - UNC Eshelman School of PharmacyThis content was independently developed by Pharmacy Times. While we acknowledge the support of our sponsor, all editorial decisions and opinions remain solely those of Pharmacy Times. Any reference to brands is for informational purposes only and not an endorsement.

You can find more information about Derek Webb, PharmD, and Dennis Williams, PharmD, BCPS, AEC, below:Derek Webb on LinkedInDennis Williams Faculty Page - UNC Eshelman School of PharmacyThis content was independently developed by Pharmacy Times. While we acknowledge the support of our sponsor, all editorial decisions and opinions remain solely those of Pharmacy Times. Any reference to brands is for informational purposes only and not an endorsement.

On Chen, MD, and Tahmid Rahman, MD discuss how plozasiran—an RNA-based APOC3-targeting therapy for patients with familial chylomicronemia syndrome with infrequent injections and a favorable safety profile—can transform care when integrated through coordinated multidisciplinary workflows with pharmacists leading patient identification, access, and monitoring.

You can find Dr. Joshi on LinkedIn here. Read more essential insights on PharmacyTimes.com.

William Van Decker, MD, discusses the key priorities of the upcoming ACC Legislative Conference, including telehealth, cardiovascular rehab, prior authorization reform, and the role of pharmacists in shaping patient-centered cardiovascular policy.

Lung cancer remains one of the leading causes of cancer-related death, yet many cases occur in people who have never smoked. One often-overlooked culprit is radon, a naturally occurring radioactive gas and the second leading cause of lung cancer.

How a new house bill could protect patient access after the IRA.

0:48: Intro 1:35: Common mistakes with inhalers 5:25: Tailoring inhaler education 9:10: Selecting the right inhaler for a patient 12:05: What an inhaler counseling session looks like 15:45: Tracking inhaler technique 18:06: Inhaler counseling in community pharmacies 21:24: Conclusion Jennifer Griffin, PharmD, MS, serves as a clinical pharmacist for Harps Food Stores, Inc., where she specializes in medical billing, point-of-care testing and treatment workflow, and marketing clinical services. She earned her Doctor of Pharmacy degree from Harding University College of Pharmacy in Searcy, Arkansas, and holds a Bachelor of Science in Healthcare Administration and a Master of Science in Health Promotion from the University of Central Arkansas. 

Kevin Chen, PharmD, MS, BCOP, CPP, and Amanda Cass, PharmD, BCPS, BCOP, share key insights about ROS1, non-small cell lung cancer, and the new approved drug taletrectinib.

Derek Webb, a community pharmacist and Virginia Board of Pharmacy member, provides comprehensive guidance on managing seasonal allergies, distinguishing symptoms, and exploring treatment options.

Jill Simonian, PharmD, received her PharmD from UCSF, followed by an acute care residency at UCSD Medical Center. Her professional career includes 25 years as a clinical pharmacist at the VA San Diego Healthcare System and a brief time as a part-time pharmacist at an independent pharmacy in Carlsbad.  She is currently conducting a course on Cannabis Pharmacology and Therapeutics at UC San Diego Skaggs School of Pharmacy and, with Dr. Peterson as co-chair, at UC Irvine School of Pharmacy. Dr. Simonian is a founding member of the Pharmacists' Cannabis Coalition of California, a nonprofit organization aimed at bridging the gap between healthcare and cannabis for the purposes of patient safety. Codi Peterson, PharmD, MS is a pediatric pharmacist and cannabis science expert. He is a PharmD graduate from Duquesne University and later graduated with an MS in Medical Cannabis Science & Therapeutics from UMaryland, Baltimore. Codi is the Chief Science Officer of The Cannigma, a science-forward media company dedicated to helping the world understand cannabis.  Dr. Peterson is also an associate clinical professor at UC Irvine, where he contributes to advancing medical education. Additionally, he teaches pharmacology to paramedics in Southern California through OCEMT, and continues to practice pharmacy in an emergency department to this day. Codi is a co-founder of the Pharmacists Cannabis Coalition of California (PCCC), a public-benefit nonprofit dedicated to educating and elevating California pharmacists in the cannabis space.

Learn more about In Our Own Voice: National Black Women's Reproductive Justice Agenda and the In Our Voice Action Fund.

This episode of Pharmacy Focus, Oncology Edition highlights key insights from the 2024 San Antonio Breast Cancer Symposium, covering new FDA-approved therapies, dose optimization strategies, and innovative prevention approaches in breast cancer care.

Expert discussed benefits of precision oncology treatments that utilize thousands of biomarkers to design personalized treatment plans.

Dr. Amina Abubakar is CEO at Avant Pharmacy and Wellness. You can connect with her on LinkedIn here. Dr. Stephen Lewis, FAAPMR, is National Medical Director of the Physiatry-Pharmacy Collaborative (PPC). You can connect with him on LinkedIn here. The Avant Institute annual symposium will take place January 31st to February 1st, 2025, in Charlotte, North Carolina at Queens University. To learn more about the institute, the resources they offer, and details about the symposium, you can access their website here. You can follow Avant Institute on LinkedIn here.

Expert discussed the potential of pelareorep, a novel immunotherapeutic agent, in treating advanced or metastatic breast cancer, particularly in HR-positive, HER2-negative patients, and the plans for further clinical development of pelareorep in this indication.

Thomas Chen, MD, PhD discussed his innovative approach to brain cancer treatment through NeOnc, Inc. 

In this episode, host Dr. Christina Madison interviews Jessica Steier, DrPH, PMP, CEO of Vital Statistics Consulting, and the founder and CEO of Unbiased Science, on her journey in public health and entrepreneurship. In a period of misinformation and disinformation, both Madison and Steier discuss the importance of creating informed, evidence-based decisions within health care. Key Takeaways: Data-Based and Evidence-Informed Decisions: Using her podcast, Unbiased Science, Dr. Jessica Steier explains that she doesn't intend to tell people what scientific opinions to have. Instead, she encourages listeners to use data and factual information to create their own evidence-based decisions to avoid falling for misinformation and disinformation. Misinformation Versus Disinformation: Dr. Steier explains that the difference in these terms revolves around intent. Misinformation refers to the unintentional spreading of inaccurate information, whereas disinformation is the intentional spread of false information. Dr. Steier also highlights a study conducted by the Center for Countering Digital Hate which found 12 people were responsible for the bulk of disinformation surrounding vaccines. The Benefits of Social Media: Although social media has been harmful in spreading misinformation and disinformation, Dr. Steier and Dr. Christina Madison discuss how it has been beneficial in emphasizing previously underdiscussed topics. As an example, they note the pain that women experience during IUD insertion, and how the mass discussion of that topic has encouraged health care practices to begin offering solutions and additional education. You can learn more about Unbiased Science podcast and Vital Statistics Consulting, and follow them on social media: Unbiased Science Podcast: Website: https://www.unbiasedscipod.com/  LinkedIn: Unbiased Science Podcast Instagram: @unbiasedscipod Facebook: Unbiased Science Podcast X (formerly Twitter): @unbiasedscipod TikTok: @unbiasedscipod Vital Statistics Consulting: Website: https://vitalstatisticsconsulting.com/  Instagram: @vitalstatisticscounsulting Facebook: Vital Statistics Consulting X (formerly Twitter): @vitstatsconsult LinkedIn: Vital Statistics Consulting, LLC  Connect with Jessica Steier on LinkedIn!

Expert shares reasons why many women are behind on their annual breast cancer screenings, along with the latest cutting edge treatment in the breast cancer space. 

The Alzheimer disease treatment landscape is rapidly changing, with several new FDA-approved antibody therapies that target amyloid plaque and aim to slow disease progression. While the controversial approval of aducanumab faced challenges, newer drugs like lecanemab and donanemab have shown more promising results in clinical trials, demonstrating cognitive benefits. Additionally, the pipeline includes novel therapies targeting tau protein and other mechanisms. Advancements in biomarker development, including plasma and imaging tests, are also enabling earlier diagnosis and the potential for preventive treatments before the onset of clinical symptoms. Experts Include: Pamela Spicer, neuroscience expert and therapy area Director, Citeline Martin Tolar, MD, PhD, founder, president, CEO, Alzheon Sharon Cohen, MD, FRCPC, medical director, site principal investigator, Toronto Memory Program

In this episode, host Dr. Christina Madison interviews the co-CEOs of Healthcare Advocate Summit Melissa Paige, BPHM, CPhT, MTM, president of National Association of Medication Access & Patient Advocacy (NAMAPA), and Elizabeth Johnson, CEO of MedicoCX, and president and co-founder of NAMAPA on Healthcare Advocate Summit and its mission. They describe how collaboration, education, and advocacy can go a long way in improving access to medications and health care. Key Takeaways: Medication Access: Medication access is a complex, systemic issue. The high cost of medication is a significant barrier for many patients, and navigating the health care system to obtain necessary medications can be confusing and overwhelming for many patients. Health Care Providers are Crucial in Improving Medication Access: Health care professionals can play a vital role in advocating for patients and assisting them in obtaining their prescribed medications. Understanding the complexities of medication access can empower health care providers to better support their patients. Patient Advocacy is Essential for Driving Change: Organizations and individuals dedicated to patient advocacy can create significant impact by raising awareness, lobbying for policy changes, and providing support to patients. Sharing personal stories can be a powerful tool for driving change in health care disparities. Collaboration and Education are Key: Partnerships between health care providers, patient advocacy groups, and policymakers are essential for addressing the medication access crisis. Educating patients, health care providers, and the public about medication access issues is crucial for creating lasting change. You can learn more about Healthcare Advocate Summit and follow the initiative on social media: Website: https://www.healthcareadvocatesummit.com/ Instagram: @healthcareadvocatesummit Facebook: Healthcare Advocate Summit X (formerly Twitter): @AdvocateSummit TikTok: @healthcareadvocatesummit Connect with Melissa Paige and Elizabeth Johnson on LinkedIn!

Olivia Kinney, PharmD, a national pharmacy practice manager at Kroger, emphasized the importance of pharmacists addressing the growing issue of vaccine hesitancy. She noted that common reasons for hesitancy include concerns about adverse effects, misinformation, access barriers, and social/political influences. Kinney advised that pharmacists can build trust by actively listening to patients' concerns, providing relevant and consistent education, and leveraging their position as trusted healthcare providers. She highlighted the value of pharmacists is in collaborating with other community organizations to improve vaccine access and literacy. Overall, she encouraged pharmacists to take a proactive, relationship-building approach to addressing vaccine hesitancy and improving vaccination rates.