Podcasts about smoldering

Figuring out if your multiple sclerosis is changing from the relapsing remitting to the secondary progressive stage can be murky. Signs of progression are discussed like slower walking and worsening memory. The underlying reasons for progression are revealed including nervous system injury, remyelination failure, chronic inflammation and aging. Practical ways to improve progressive symptoms are shared. Successful trials for disease-modifying therapy for secondary progressive multiple sclerosis (SPMS) are highlighted. Tolebrutinib, under expedited review by the FDA, has been shown to slow down progression in SPMS patients by targeting cells in the central nervous system causing chronic inflammation. Introducing our new co-host Jamie Holloman MD from The MS Center for Innovations in Care!  Dr. Holloman completed in neurology residency at Washington University, followed by a 3-year fellowship at the Cleveland Clinic.  He interviews: Christopher Laganke MD, Founder of the Joanne P. LaGanke MS Center, Cullman, Alabama Barry Singer MD, Director of The MS Center for Innovations in Care, Missouri Baptist Medical Center, St. Louis    

Jason takes a break from our study of Acts to bring us the message: "Bruised Reeds Smoldering Wicks". If you are struggling with faith, bring what you have to God, and ask for help, so that he can repair your faith.

Faced with a seemingly unwinnable fight and the option to flee, Sirio must decide whether to hold firm with his party.WebsiteDiscordTwitterPathfinder Second Edition and the Kingmaker Adventure Path are published by Paizo."Take the Lead" and other featured music were composed by Kevin MacLeod and licensed under Creative Commons by: Attribution 4.0 License.All ambiances were composed by Michael Ghelfi Studios.The Zero Check are committed to providing an inclusive and respectful experience to all listeners, but we also recognize and acknowledge that we are limited by our individual frames of reference. If we misstep, please let us know. Email all feedback to feedback@zerocheckpodcast.com.Thank you for listening to The Zero Check. Send us a text

Hawk gives his insight on the Browns drafting Shedeur Sanders, Mike Ryan previews Pat Riley's exit press conference and Roy tells us where he was when his neighbor's house set on fire. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The LoG return home to Downton Abbey for a Springtime surprise. Mary is knee deep in her new boyfriend drama, juggling Charles Blake and Tony Gillingham. Mr. Bates goes for a day trip. Can Cora plan the bazaar without Robert? To support the LoG on Patreon visit: https://www.patreon.com/lordsofgrantham To buy LoG Merchandise visit: https://www.teepublic.com/user/lords-of-grantham-podcast

On Open Line CHATT, Dr. Michael Rydelnik answers questions about verses from Isaiah 42; are they Messianic descriptions of Jesus leading up to Isaiah chapter 53? Michael also addresses questions about women who served at the tabernacle, about the festival in John chapter 7, and about when Jesus said that there will be a time when all who are in their graves will hear His voice and come out. 'What exactly does that mean, and when will that occur?'Donate to Moody Radio: http://moodyradio.org/donateto/morningshow/wmbwSee omnystudio.com/listener for privacy information.

Stephanie wants answersBy LiminallySpaced. Listen to the Podcast at Explicit Novels.As the get together wound down, I hung back and helped clean up. Denny attempted to do the same, but was finally hustled out of the house by Roberto, who needed a ride home. It was Just Christine and I now, and as we finished tidying up, we sat alone by the shallow end of the pool as the sun got low in the sky."They're a nice group of kids," I said, kicking my feet in the water, "that Denny guy really has the hots for you, huh?"She smiled an embarrassed smile and swiped her long hair back behind her ear."He's harmless. He has the hots for everyone. He and Talia dated for a hot second, but I think she might have been too much bite for his bark.""Yeah, she's something else," I said with a chuckle, "really nice, she cornered me over by the pizza and wouldn't let me leave till we exchanged screen names."Christine laughed, but there was a hesitation to her laugh; a reticence. Had that cold pang of jealousy possibly hit her deep inside like it had me?"So what's going on, Tim, you clearly have something on your mind," she said with a kind timber to her smoky voice."I did, I do. It's, Stephanie.""The girl from the limo?" she said, shifting her hips as one long leg dangled down in the water. Christine knew Stephanie as my prom date. As "the girl from the limo" ;  the girl she saw passionately sucking my cock that night."Yeah," I said.I swear I saw her lightly lick her lips.From there, I just vented fully. I told her everything. The whole story, from the first time I heard Stephanie's orgasmic moans to the night in the limo, to my fracture with Tara, to the first time we had sex, all the way through to the events of last night, Christine listened to it all closely and intently."I'm sorry, that was, a lot," I said timidly once I finished."No, no, don't apologize," she said as she scooted herself closer to me. She placed her hand on my hand. "This is all really emotionally complex, I totally get how much it's been weighing on you. It sounds to me like you were willing to let Stephanie play some games with you, maybe you even enjoyed it, but once she started affecting other people you cared about it became too much, which is all totally understandable." I felt the soft waves made by her dangling leg against my calf. "It sounds to me like she's a very self conscious person, Tim; she wants to protect herself from getting hurt, but she took it too far. I've always thought honesty was the best option. You need to tell Stephanie how you feel, because right now it's up to her to make it right.""Yeah, I don't know, I'm not really interested in talking to her right now." I said, feeling Christine's thumb stroking the back of my hand."When you're ready, of course. Just try not to live with regret, whatever you do.""Thanks, Christine, you're a great friend," I said, pulling her hand up to my mouth to kiss it."My pleasure. You've listened to my struggles enough times, I'm happy to listen to yours for once."Her struggles. I suddenly remembered her struggles. That internal conflict between the godly and the carnal that caused her to break up with her boyfriend in an attempt to stay pure, and led her to the front seat of my car, a spasming cunt, and a mouthful of my cock."And how is 'your struggle,'" I floated.I felt her wading foot brushing my leg as it glided back and forth in the water."I'm, losing," she said, looking up at me with an unmistakable look in her eyes: lust. "But I think I've found a new approach."This time there was no missing her tongue sneaking out to moisten her lips. Her loose button down had fallen off one shoulder, giving me a tantalizing peak at her bikini top."I have desires, needs," she began as she started to run her hand up and down my forearm very suggestively, "I know I can't deny them, but I think I can at least deal with them responsibly, if I have someone responsible who can help me."My cock surged to life."Are you a responsible person, Tim?" she said as her eyes bore a hole through me. My friend, the pastor's daughter, the churchiest girl I knew, was asking me something very, very sinful. And it was hot as fuck."Extremely." I croaked out."There are just certain, rules, we have to abide by, ok?" She said, her breath getting slightly ragged."Ok, Like what kind of rules?" I said, pulse quickening."We can't have sex, in fact I can't let you touch my body at all,” she said, dropping her head. My enthusiasm dropped. I wanted nothing but to run my hands all over her gorgeous body, feel how wet she undoubtedly was.Her eyes slowly lifted to meet mine as she finished her statement.“ but everything from the neck up is fair game."My eyebrows shot up as quickly as my cock."Does that work for you? Are you willing to help me get through the summer?" she said, running her hands over my arm faster, practically jerking it off."Why me?" I asked dumbly. She was my friend, I knew how difficult this all had been for her, and I didn't want my cock to do the thinking for me here."Because I trust you," she said in that smoky, erotic voice of hers, "I know you won't cross any line I don't want to cross. I know you'll be, respectful." That last line had enough syrup on it for a whole stack of pancakes."The neck up is fair game?" I said, hardly believing the offer in front of me. All thoughts of Stephanie were gone from my head as I took in the sight of this wanton, lusty church girl dying for release.Her small bosom rose and fell heavily as she looked me in the eyes and slowly nodded.I decided to put things to the test. My eyes never leaving hers, I slowly reached over with my free hand and softly caressed the curve of her face. Her eyes shut. She exhaled a heavy sigh.I gently ran my thumb over her glistening lips, feeling how soft they were. I felt Christine shake as a chill ran through her. I circled them slowly, as if asking a question.Christine's eyes opened slowly. She looked at me, and as if answering that question, parted her lips and took my entire thumb into her wet mouth with a low moan.Now it was my turn to shudder as a chill ran through my body.Christine's hands slid up and held my wrist steady as she worked my thumb in and out of her mouth slowly. Eyes closed as if in rapture, she lolled my thumb around in her mouth, teasing me with her tongue, savoring every inch that she dragged her lips along.My pulse was racing, my breath was shallow, and my cock was rock hard, desperately fighting to get out of my swim trunks.The light of the low sun behind her framed her in a golden glow, her lovely hair bouncing ever so slightly in the warm summer breeze. Her exposed shoulder rocked forward as she sucked, daring me to touch her perfect skin. Her rigid nipples protruded sharply against the fabric of her bathing suit.Looking at this wanton beauty in front of me, this creature of goodness, haunted by repressed lust, I had had enough. I didn't want to take advantage, but she had rationalized it enough in her own head. This is what she wanted. And she wanted me, trusted me, to be the one to help her.How could I ever refuse?My thumb slipped out of her wet mouth with a slight slurp, I reached my fingers back along her face to the back of her neck, and pulled her gently, but firmly, into a hot kiss.A sigh of relief leapt out of her body excitedly as our lips touched, and almost instantly I felt the warm wriggle of her tongue plunge into my mouth. It was neeful. It was aggressive.I felt her hand grip the inside of my thigh. I groaned in pleasure, and my hand slipped down onto the flat of her upper chest.Christine immediately pulled away from our kiss."I'm serious, Tim, really, neck up only." She said assertively, but not angrily."I'm sorry, it was an accident, really," I stammered. She understood my dilemma. This was new to both of us, and there was going to be a bit of an adjustment period. "But I mean, at the same time,” I said, gesturing down to her hand gripping my inner thigh mere inches below my balls.She smiled a coy, sexy smile, and leaned in close enough to whisper "The rules are You can't touch Me below the neck." I felt her hand start to slide up my thigh. "Is that going to be ok with you?"My cock surged at the double standard. The church had taught her well.I slowly slipped my hand up the back of her neck, and lightly grasped a hand full of her long, brown hair right at the root."So this is ok?" I said, pulling slightly.Christine's mouth hung open as she gasped."Yes," she said through ragged breath, "very ok."I matched her smile with my own and pulled her back in for another kiss.Our tongues sparred breathlessly again, and her hand slipped closer to my balls.Gripping her hair tighter, I tipped her head back, revealing her long, elegant neck. A devilish smile broke out on her lips with an accompanying gasp.I leaned in and began peppering my lips and tongue all over the soft exposed flesh of her neck. From the hollow above her collar bone up to the tip of her chin, I treated her entire neck the same way I treated Stephanie's cunt, and by the sounds Christine was making, it was having a similar effect.Her hand finally gripped my balls through my trunks. She squeezed. I moaned. I felt her throat shuffle beneath my lips as she swallowed some air in near rapture.Suddenly Christine pushed me back, and in a flash she was on top of me. Straddling my hips, our lips met again, but this time there was a new sensation: pressed tight against my cock, gyrating, grinding, was Christine's hot cunt, covered only by the thin material of bathing suit bottoms and short shorts.My hands still tight in her hair, I tipped her head back again, redoubling my efforts on her neck with my lips and tongue as the preacher's daughter rubbed her cunt against my iron-hard cock. I could tell from the way her hands gripped and grabbed at me that pleasure was shooting through her young body.This was going to be tougher than she thought to play by her rules, I think. This girl clearly wanted to fuck.As if she read my mind, Christine all of a sudden rolled herself off of me, and each sucked in air catching our breath. We chuckled at what was transpiring between us, two friends from church, and I watched as Christine ran a cleansing hand around her face, down her neck, over her breasts, across her flat stomach, and down between her legs before quickly pulling away. It made me a little bit sad to see how quickly she removed her hand from between her legs. Christine was clearly a very sexual girl, but her upbringing and religion made her push that part of her so far down. I wondered if she had ever even masturbated before.Wanting nothing more than to make her feel good now, I leaned back in toward her, but her hand on my chest stopped my advancement. She gently pushed me back to my seated position, legs dangling in the water.Dipping in to kiss me once, that devilish smile returned to the church girl's face, and in one smooth motion she slipped her lithe body into the water of the pool.Being in the shallow end, the water barely came up to the crotch of her pants. As she waded her way over to me, the waves lapped at her ass deliciously.There was a fire in her eyes now of pure want. Running her hands impatiently up my thighs, she grasped onto the waistband of my swim trunks and began to pull. Not wanting to stand in the way of what this girl needed, I lifted my hips and shimmied slightly as Christine removed my pants completely, freeing my hard, straining cock to the warm evening air.Never taking my eyes off my proud, erect cock, Christine pushed my legs apart, and sank to her knees between them. A single step ran along the bottom edge of the pool, and when on her knees, this brought the warm, lapping water right up to the bottom of her small breasts, and put her in perfect cocksucking position.But there was something else as well. Before she even touched me, Christine's eyes closed breathlessly, and a pleasurable grin pulled at her lips. Her hands rubbed up and down my bare thighs, and I watched her shift and gyrate as if searching for the perfect position. When her eyes shot open with a gasp and I felt her nails dig into my thighs I knew she had found it: Christine had positioned herself perfectly so the pulsing spray of the pool jet hit her directly on the clit.Invigorated by the new source of pleasure, her hands closed in on me from either side, and I finally felt Christine's fingers wrap around the length of my dick.Now it was my turn to moan.Her hands played with me gently, stroking my shaft, squeezing my big, full balls, all while the pool jets peppered her cunt with a constant stream of pressurized water. She giggled, she smiled. She shook with small euphoric shocks.My cock still in her hands, she leaned up and kissed me on the lips. Almost like a signal that things were about to really heat up, she pulled away from our kiss, licked her lips wet, dropped her head down and took the tip of my cock into her salivating mouth.I gasped loudly.Holding my shaft and balls firmly, not stroking, not squeezing, Christine suckled at the head of my cock with delight. Pressure built in my tip, flaring it out purple and desperate. Her lips and tongue danced around it like she was desperately trying to save a melting ice cream.The entire universe was in the swollen end of my cock, and Christine made a meal out of it. Wet tongue sliding in circles around it, teasing the underside, closed lips sucking in short bursts like I was her own personal lollipop; it felt amazing.I was squirming with each suckle, with each lash of her tongue, and the building pressure made my tip extremely sensitive. It wasn't going to make me cum, but it was an overwhelming sensation of acute pleasure I had never quite experienced before.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME information, and to apply for credit, please visit us at PeerView.com/DWJ865. CME credit will be available until April 2, 2026.BTK Inhibition as an MS Treatment Strategy: Targeting Smoldering Neuroinflammation In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Sanofi.Disclosure information is available at the beginning of the video presentation.

Returning to the show, Drs. Vincent Rajkumar and Aaron Goodman engage in a dynamic debate over the evolving landscape of smoldering multiple myeloma, focusing on the highly anticipated study recently co-authored by Dr. Rajkumar and published in The New England Journal of Medicine after being presented at ASH 2024. They dissect the study's findings, which highlight the impact of early intervention with daratumumab in delaying disease progression for patients classified as high-risk. The discussion explores the nuances of smoldering myeloma classification, the controversy surrounding risk stratification, and the historical context of prior studies that failed to change clinical practice. With their expert insights, Drs. Rajkumar and Goodman break down the implications of this research, questioning whether it truly shifts the standard of care and what it means for future treatment approaches. View the NEJM publication. https://www.nejm.org/doi/abs/10.1056/NEJMoa2409029 Check out Chadi's website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

This special episode of RealTalk MS is sponsored by Sanofi.  By now, you may have come across the term smoldering MS and wondered what it means. An international panel of MS experts has published a consensus statement on the definition, biology, and clinical implications of smoldering MS. Joining me is the lead author of that paper, Dr. Antonio Scalfari. Dr. Antonio Scalfari has a research background in multiple sclerosis and neuro-inflammatory conditions. From 2003 to 2006, he was a clinical fellow in the neurology department of Oxford University. In 2011, Dr. Scalfari obtained his PhD in neuro-epidemiology at Imperial College London, where he was then a post-doctorate research fellow from 2011 to 2013. Since 2006, Dr. Scalfari has been working at the London North West Healthcare NHS Trust, and in 2013, he started working at the multiple sclerosis unit at Imperial College Healthcare NHS Trust. In 2017, Dr. Scalfari was appointed as a substantive consultant neurologist. Along with other consultants, he manages the multiple sclerosis and neuro-inflammatory diseases service at Charing Cross and St Mary's hospitals and is a general neurologist at London North West Healthcare NHS Trust. Sanofi convened the meetings and paid for medical writing assistance, but the authors worked independently to develop and draft the consensus statement. While Dr. Scalfari has been compensated by Sanofi, his views and opinions are his own and do not necessarily reflect those of Sanofi.

Episode 184: Multiple Myeloma BasicsSub-Interns and future Drs. Di Tran and Jessica Avila explain the symptoms, work up and treatment of multiple myeloma. Written by Di Tran, MSIV, Ross University School of Medicine; Xiyuan Yang, MSIV, American University of the Caribbean. Comments by Jessica Avila, MSIV, American University of the Caribbean. Edits by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Di: Hi everyone, this is Di Tran, 4th year medical student from Ross university.  It's a pleasure to be back.  To be honest, this project is a part of teamwork of two medical students, myself and another 4th year, her name is XiYuan.  She came from the AUC. Unfortunately, due to personal matters she was unable to make it to the recording today which makes me feel really sad. Jessica: My name is Jessica Avila, MSIV, American University of the Caribbean.Di: The topic we will present today is Multiple Myeloma. Multiple myeloma is typically a rare disease and it's actually a type of blood cancer that affects plasma cells in the bone marrow.Jessica: Let's start with a case: A 66-year-old male comes to his family doctor for an annual health checkup. He is not in any acute distress but he reports that he has been feeling tired and weaker than usual for the last 3 months. He also noticed that he tends to bruise easily. He has a history of arthritis and chronic joint pain, but he thinks his back pain has gotten worse in the last couple of months. Upon checking his lab values, his family doctor found that he has a calcium level of 10.8 and a creatinine level of 1.2, which has increased from his baseline. Given all that information, what do you think his family doctor is suspecting? And what kind of tests she can order for further evaluation?Di: Those symptoms sound awfully familiar – are we talking about the CRAB? You know, the diagnostic criteria for Multiple Myeloma.Jessica: Exactly! Those are called “myeloma-defining events.” Do you remember what those are?Di: CRAB criteria comes in 4 flavors.  It's HYPERCALCEMIA with >1mg/dL, RENAL INSUFFICIENCY with serum creatinine >2mg/dL, ANEMIA with hemoglobin value 10% plasma cells, PLUS any one or more of the CRAB features, we can make the official diagnosis of multiple myeloma. Di:  Before we go deeper, let's back up a little bit and do a little background.  So, what do we know about the immunoglobulins, also known as antibodies? Back from years of studying from medical school, we know that the plasma cells are the ones that producing the antibodies that help fight infections.  There  are various kinds that come with various functions.  Each antibody is made up of 2 heavy chains and 2 light chains.  For heavy chains, we have A, D, E, G, M and for light chains we have Kappa and Lambda.Jessica: Usually, the 5 possible types of immunoglobulins for heavy chains would be written as IgG, IgA, IgD, IgE, and IgM.  And the most common type in the bloodstream is nonetheless the IgG. Di: What is multiple myeloma? In myeloma, all the abnormal plasma cells make the same type of antibody, the monoclonal antibody.  The cause of myeloma is unknown, but there are lots of studies and evidence that show a number of potential etiologies, including viral, genetic, and exposure to toxic chemicals, especially the Agent Orange, which is a chemical used as herbicide and defoliant. It was used as a chemical warfare by the U.S. military during the Vietnam War from 1961 to 1971.Jessica: We need to order some specific blood tests to see if there is elevated monoclonal proteins in the blood or urine. So, to begin with we'll need to take a very thorough history and physical exam. Next, we'll do labs, such as CBC, basic metabolic panel, calcium, serum beta-2 microglobulin, LDH, total protein, and some not so common tests: serum protein electrophoresis (SPEP), immunofixation of blood or urine (IFE), quantitative immunoglobulins (QIg), serum free light chain assay, and serum heavy/light chain ratio assay.If any of the results is abnormal, we should consider referring our patient to an oncologist.Di: Interesting! I read that Multiple Myeloma symptoms vary in different patients.  In fact, about 10-20% of patients with newly diagnosed myeloma do not have any symptoms at all.   Otherwise, classic symptomatic presentations are weakness, fatigue, increased bruising under the skin, reduced urine output, weakened bones that is likely prone to fractures, etc. And if multiple myeloma is highly suspected, a Bone Marrow biopsy should be done with testing for flow cytometry and fluorescent in situ hybridization (FISH). Actually, if any of the “Biomarkers of malignancy (SLIM)” is met we can also diagnose multiple myeloma even without the CRAB criteria. Jessica: The diagnosis is made if one or more of the following is found: >= 60% of clonal plasma cells on bone marrow biopsy, > 1 lytic bone lesion on MRI that is at least 5mm in size, or a biopsy confirmed plasmacytoma. Di: Imaging comes in at the final step especially if we able to find one or more sites of osteolytic bone destruction > 5mm on an MRI scan.Jessica: What if the bone marrow biopsy returns > 10% of monoclonal plasma cells, but our patient doesn't have either the CRAB or the Biomarker criteria? Di: That's actually a very good question, since Multiple Myeloma is part of a spectrum of plasma cell disorders. That's when smoldering myeloma comes into play. It is a precursor of active multiple myeloma. Smoldering myeloma is further categorized as high-risk or low-risk based on specific criteria.A less severe form is called Monoclonal Gammopathy of Undetermined Significance, or simply MGUS, with < 10% bone marrow involvement. Those are diagnoses we give once we rule out actual multiple myeloma, which are defined by the amount of M-protein in the serum.Jessica:  When to get started on treatment? Multiple Myeloma is on a spectrum of plasma cells proliferative disorders, starting from MGUS to Smoldering Myeloma, to Multiple Myeloma and to  Plasma Cell Leukemia.  Close supervision/active watching is enough for MGUS and low risk Smoldering Myeloma. But once it has progressed to high-risk smoldering myeloma or to active Multiple Myeloma, chemotherapy is usually required. Some situations may require emergent treatment to improve renal function, reduce hypercalcemia, and to prevent potential infections.Di: As of 2024, treatment of Multiple Myeloma comprises the Standard-of-Care approved by the FDA. In fact, the quadruple therapy is a combination of 4 different class of drugs that include a monoclonal antibody, a proteasome inhibitor, an immunomodulatory drug, and a steroid. Jessica: They are Darzalex (daratumumab), Velcade (bortezomib), Revlimid (lenalidomide) and dexamethasone.  Other treatment plans for Multiple Myeloma include chemotherapy, immunotherapy, radiation therapy (for plasmacytomas) and stem cell transplants. The patient will also be on prophylaxis acyclovir and Bactrim while on chemotherapy. Sometimes anticoagulants are also considered because the chemo increases the risk of venous thromboembolic events.Di: Although the disease is incurable, but with the advancing of novel therapies and clinical trials patients with multiple myeloma are able to live longer.  Problem is the majority of patients diagnosed with Multiple Myeloma are older adults (>65), the risk of falling is adding to multiple complications of the disease itself, such as bone density loss, pain, neurological compromises, distress and weakness.  Palliative care may come in help at any point in time throughout the course of treatment but is most often needed at the very end of the course. Jessica, can you give us a conclusion for this episode?Jessica: Multiple Myeloma may not be the most common cancer, but we have to be aware of the symptoms and keep it in our differential diagnosis for patients with bone pain, easy bruising, persistent severe headaches, unexplained renal dysfunction, and remember the CRAB: HyperCalcemia, Renal impairment, Anemia and Bone lesions.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:International Myeloma Foundation. (n.d.). International Myeloma Working Group (IMWG) criteria for the diagnosis of multiple myeloma. https://www.myeloma.org/international-myeloma-working-group-imwg-criteria-diagnosis-multiple-myeloma Laubach, J. P. (2024, August 28). Patient education: Multiple myeloma symptoms, diagnosis, and staging (Beyond the Basics). UpToDate. https://www.uptodate.com/contents/multiple-myeloma-symptoms-diagnosis-and-staging-beyond-the-basics.University of California San Francisco. (n.d.). About multiple myeloma. UCSF Helen Diller Family Comprehensive Cancer Center. https://cancer.ucsf.edu/research/multiple-myeloma/about Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

KMOX Reporter Maria Keena joins the show to talk about Missouri officials saying that there is a high likelihood of radioactive waste in smoldering landfill near Rams old practice facility.

AQUILA is a constellation shaped like an eagle, and also a hotly debated myeloma trial of daratumumab in smoldering multiple myeloma. In this episode, Bernie and Anthony are joined by myeloma expert Manni Mohyuddin to discuss the study's findings and whether or not they should change practice! Grab a drink and listen in for an exciting discussion. Note: L'aquila is Italian for eagle! AQUILA: Dimopoulos MA, et al. N Engl J Med. 2024 Dec 9. doi: 10.1056/NEJMoa2409029. Epub ahead of print. PMID: 39652675.

With a task to complete from their new local "friends" the group has a number of things to look into before they are ready to set their sights on their next goal. But first, it's time to see a necromancer about a vampire... Music in this episode is: "Suonatore di Liuto" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Rambling Cello II" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Ever Mindful" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Hybrid Ambience" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Long Note Three" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Mysterium B" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Orchestral Ambience" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Twilight" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Shadowlands - Horizon" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Long Note One" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Tense Atmosphere" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Combat Sequence A" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Sleepers" by Sergey Cherimisinov, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "Silver Flame" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Background Woodwinds and Stings" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Smoldering" by Kai Engel, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives;     Sound Effects by Epidemic Sound, Mixkit and Pixabay

AP correspondent Julie Walker reports on the California Wildfires.

Jesus is the only and best hope for bruised reeds and smoldering wicks like us.

Isa. 42:1-4 Sermon 12/29/2024 Sermon Notes: https://www.opendoorcommunity.net/uploads/6/3/0/8/63085847/12-29-24.pdf Email: PastorKenWilson@gmail.com WebSite: https://www.opendoorcommunity.net/ YouTube: http://www.youtube.com/c/OpenDoorCommunityChurchAugusta FaceBook: https://www.facebook.com/OpenDoorCommunityAugusta Donations: https://www.opendoorcommunity.net/donations.html

After a successful night of drinking, and learning a few more things than they knew before, it is time to head up to the isolated Arcanist Halls. Hopefully the streak of finding out answers (even little ones) will continue. Music in this episode is: "Suonatore di Liuto" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Elvish Waiting Theme" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Dark Times" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Forest Allies" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Long Note Two" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Attempts" by Alex Mason, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "New Day" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Silver Flame" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Lost Frontier" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Hope" by Alex Mason, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "Existing" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Orchestral Ambience B" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Aldrassil" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Silver Flame" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Contemplation Loop" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Virtutes Instrumenti" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Existing" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Woodwinds and Harp" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Ossuary 6 - Air" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Anguish" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Smoldering" by Kai Engel, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives;     Sound Effects by Epidemic Sound, Mixkit and Pixabay

There are only more questions, not more answers. And none of those answers seem to have good conclusions. With Kashan and Jasper gone, and the past coming back to haunt (and hunt) our adventurers, they need to take steps to move forward. Music in this episode is: "Suonatore di Liuto" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Rambling Cello II" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Idle" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Existing" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Silver Flame" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "River Fire" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "No More Words" by Alex Mason, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "Monomyth - The Distant Sun" by Scott Buckley, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, ScottBuckley.com.au; "Tavern Music" by TabletopAudio, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, TabletopAudio; "Night Vigil" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Anticipation" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Northern Lullaby" by Sergey Cherimisinov, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "Smoldering" by Kai Engel, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives;     Sound Effects by Epidemic Sound, Mixkit and Pixabay

The next step of the journey is here as the group takes their first steps into a new city. Their paths have continued to weave together leading them further and further down this path to the Gods only know where... Music in this episode is: "Suonatore di Liuto" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Attempts" by Alex Mason, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "New Day" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Lost Frontier" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "River Fire" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Rites" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Virtutes Vocis" by Kevin MacLeod, Licensed under Creative Commons: By Attribution 4.0 License, Incompetech; "Contemplation Loop" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Background Strings C" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Forsaken Sanctum" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Northern Lulaby" by Sergey Cherimisinov, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives; "Orchestral Ambience" by Tyler and Noah Rich, Licensed under Creative Commons: By Attribution 4.0 License, Monumental Studios; "Smoldering" by Kai Engel, Licensed under Creative Commons: Attibution-NonCommercial 4.0 International, Free Music Archives;   Sound Effects by Epidemic Sound, Mixkit and Pixabay

Fire crews are getting ready to drive that cargo full of lithium-ion batteries -- which is still smoldering -- to a remote location at the Port of L.A. A burglary crew hits three pharmacies in the San Fernando Valley in a matter of hours, and the L.A. County Sheriff's Department has a new center that's using technology to improve public safety.

Patreon preview. Unlock full episode at https://www.patreon.com/stavvysworld Tommy McNamara joins the pod to discuss growing up in Chicago, his midwestern family's love of diet soda, the ice cream of the future, going to church hammered, beautiful bible verses about donkeys and horses, getting trash talked by an opposing coach as a young tennis player, and much more. Tommy and Stav help callers including a guy who caught his girl texting with an ex, and a man whose girl is extremely jealous after he lost a bunch of weight. Watch Tommy McNamara's special SMOLDERING out now: https://www.youtube.com/watch?v=ViNPDchxUe4 Follow Tommy McNamara on social media: https://www.instagram.com/tommymcnam https://twitter.com/TommyMcNam Wanna be part of the show? Call 904-800-STAV and leave a voicemail to get advice!

This week Amanda and Wade welcome amazing imroviser and actor Nick Trotter to the podcast to discuss the 1999 Jim Jarmusch classic film, Ghost Dog: The Way of the Samurai.  The trio talk about the organic filmmaking of Jarmusch, themes of decay and incompitable, yet not completely unuseful systems of morality, and lots and lots of discussion about pigeons. Plus, our awesome friend Sama gets namechecked a few times. Listen in and enjoy! Credits: https://www.instagram.com/dontworrybmovies/ Logo – John Capezzuto https://www.creativecap.net/ Intro and Outro Music – Andrew Wolfe of Darling Overdrive https://www.instagram.com/darlingoverdrive/?hl=en Additional Music: Note: Some songs may have been adapted from their original form to fit the length of our segments "Smoldering" by Kai Engel (www.freemusicarchive.org/music/Kai_Engel/Chapter_Four__Fall/Kai_Engel_-_Chapter_Four_-_Fall_-_09_Smoldering/) "The Energy of Sound - 432Hz.mp3" By Almusic34 (www.freemusicarchive.org/music/almusic34/single/the-energy-of-sound-432hzmp3/)

| All CoR Links | https://www.podcastcor.com | Music By Slayur | https://www.linktr.ee/slayur | Story By | Roy Graham

~ Rebuking a Smoldering Wick ~ Job Teaching Series, Part 18

Video version here: https://www.youtube.com/live/21w4W7DSLWU Talking holding the Stanley Cup, Caddying for an NHL legend and some other caddy stories, the reason NOW I want Trump to win, Opie and Anthony hanging with Dice and how much fun that was, watched Dark Side of Comedy featuring Chris Farley, Andrew Dice Clay and Artie Lange, looking at putting a radio show together like an artist looking at a empty canvas, Rob Reiner will do WHAT if Trump is elected and more! #funnypodcast #comedypodcast #hamptons #longisland #beachlife #opieandanthonySee omnystudio.com/listener for privacy information.

In the first part of a new series, I am delving into one of the greatest wonders of the world and all the myths that have developed surrounding it. Join me as I look into pyramid myths! Direct all advertising inquiries to advertising@airwavemedia.com. Visit www.airwavemedia.com to find other high-quality podcasts! Find a transcript of this episode with source citations and related imagery at www.historicalblindness.com sometime before the release of the next episode. Pledge support on Patreon to get an ad-free feed with exclusive episodes! Check out my novel, Manuscript Found!  And check out the show merch, which make perfect gifts!  Further support the show by giving a one-time gift at paypal.me/NathanLeviLloyd or finding me on Venmo at @HistoricalBlindness. Some music on this episode was licensed under a Blue Dot Sessions blanket license at the time of this episodes publication. Tracks include "Cicle DR Valga." Other music, including "Remedy for Melancholy," "daedalus," "daemones," "Smoldering," "Seeker," and "Plague" are by Kai Engel, licensed under Creative Commons. Learn more about your ad choices. Visit megaphone.fm/adchoices

Roz shields her eyes for the arrival of supernova writer, comedian, actor and co-host of Double Threat, Julie Klausner! Smoldering beneath bangs and huge sunglasses, the two discuss reincarnation, thoughtographer Ted Serios, and why Julie won't stay in old hotels anymore. Want to share YOUR paranormal experience on the podcast? Email your *short* stories to GhostedByRoz@gmail.com and maybe Roz will read it out loud on the show... or even call you! Be sure to follow the show @GhostedByRoz on Instagram. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwYCsr Learn more about your ad choices. Visit megaphone.fm/adchoices

It's Luke Mones Explained. Our guest this week is the legendary comedian and man of the people Tommy McNamara (@TommyMcNamaraComedy). This is the greatest hour in the history of American media.   Connect with Luke! Twitter: https://X.com/LukeMones  Instagram: https://www.instagram.com/LukeMones  Tiktok: https://www.tiktok.com/LukeMones Youtube: http://www.youtube.com/@LukeMones  Facebook: https://www.facebook.com/LukeMones    Connect with Tommy! http://www.tommymcnamara.com  https://www.instagram.com/tommymcnam/  Tommy's new special SMOLDERING: https://www.youtube.com/watch?v=ViNPDchxUe4  #LukeMones #standup #comedy #podcast #entertainment #TommyMcNamara

Today, I have the honor of interviewing Dr. Gabriel Pardo. He is a physician and a scientist that aims to provide comprehensive care to individuals with MS through a multidisciplinary approach. On today's episode, we talk about smoldering MS, new terminology that explains worsening of function without changes on an MRI, aging out of disease modifying therapies and the effects of BTK inhibitors. Dr. Gabriel Pardo is a physician and a scientist that aims to provide comprehensive care to individuals with Multiple Sclerosis through a multidisciplinary approach while also participating in clinical research. He is the Director Oklahoma Medical Research Foundation Multiple Sclerosis Center of Excellence. Connect with Dr. Pardo: Website: https://omrf.org/ Twitter: @docforms Additional Resources: https://www.doctorgretchenhawley.com/insider Reach out to Me: hello@doctorgretchenhawley.com Website: www.MSingLink.com Social: ★ Facebook: https://www.facebook.com/groups/mswellness ★ Instagram: https://www.instagram.com/doctor.gretchen ★ YouTube: https://www.youtube.com/c/doctorgretchenhawley?sub_confirmation=1 → Game Changers Course: https://www.doctorgretchenhawley.com/GameChangersCourse → Total Core Program: https://www.doctorgretchenhawley.com/TotalCoreProgram → The MSing Link: https://www.doctorgretchenhawley.com/TheMSingLink

Outside the fallen city of Desa, our heroes contend with traps and each other as they push towards something terrible. -- Notes: This episode contains content warnings. Visit ⁠⁠⁠⁠⁠⁠badheroescast.com/contentwarnings⁠⁠⁠⁠⁠⁠ for more details. Check out ⁠⁠⁠shop.badheroescast.com⁠⁠⁠ for art prints and new merch! We're raising money to commission a special set of illustrations depicting iconic scenes from The Scattered Pawns. Donate at ⁠⁠⁠⁠⁠⁠ko-fi.com/badheroes⁠⁠⁠⁠⁠⁠ if you want to help! Subscribe to our new free Patreon tier at ⁠⁠patreon.com/badheroes⁠⁠ to get news and updates about the show. -- Music: "Hopeful," "Harp Waltz," "Conjuring," "They're Crawling" and "Insidious" by Monument Studios "modum," "Plague," "Smoldering" and "Imminence" - Kai Engel "Inexorable," "Night Vigil" "Darkest Child" and "Deep Haze" - Kevin MacLeod "Solve the Damn Mystery" - Jesse Spillane Sound effects by klankbeeld, leonelmail, Johnny2810, Rmutt, TRP, bree0701, kyles, felix.blume, joaomjaraujo, Manim8, J.R.Mythical, Andy19 and szczur_banshee on ⁠⁠⁠⁠⁠⁠⁠freesound.org⁠⁠⁠⁠⁠⁠, with additional sounds by Monument Studios. -- This episode features a promo from Shrimp and Crits. Bad Heroes is sponsored by Roll20! Visit ⁠⁠⁠⁠⁠roll20.net⁠⁠⁠⁠⁠ to create your free virtual tabletop today.

Sometimes, Life Can Make Us Feel Overwhelmed, Damaged, or ExhaustedIf that's you, here's a some help through the power of learning to abide in God's presence, and some surprising ideas from scripture and science about learning to heal and hear.Scripture: Isaiah 30, Matthew 12:20Five Ways You Can Support this show:Pray for us!Subscribe, like, and share it with your friends! (We even have a YouTube channel!)Leave reviews and comments wherever you listen to podcasts!You can become a paid partner of the podcast and get special bonus episodes and lots more content by clicking here. Visit one of our affiliate partners and consider using their products (we use them every day):Improve your gut health, immune system, and protect your brain with Pique!Other Helpful Links:Click here to access the Hope Is the First Dose playlist of hopeful, healing songs!Be sure to check out my new book, Hope Is the First Dose!Here's a free 5-day Bible study on YouVersion/BibleApp based on my new book!Sign up for my weekly Self-Brain Surgery Newsletter here!All recent episodes with transcripts are available here!

The U.S. Environmental Protection Agency approved a rule this week that will allow gasoline blended with higher amounts of ethanol to be sold year-round in eight Midwestern states, including Minnesota.And Canadian wildfires brought smoke and hazy skies to Minnesota last summer. Some of those fires are still smoldering underground.Those stories and more in today's evening update from MPR News. Hosted by Emily Reese. Music by Gary Meister.

This week, Jax, CrushU, Slushyotter, and Freeeshooter talk about items and Smolder! Then they answer some listener questions! Keep those questions coming to fourwards@trinityforcepodcast.com so we can answer them on the show! We NEED more questions! WE'RE LOW!!!     Sponsors: We don't have any right now! If you represent a brand and want to sponsor the podcast, send us an email, we'll get you talking to the right people.   ---- Please continue to support the network by reviewing us on iTunes and donating to the Trinity Force Network at http://patreon.com/tforcenetwork  Links Referenced Old Episodes: https://www.trinityforcenetwork.com/show?id=41 TForce Discord: discord.trinityforcenetwork.com Hope you love the episode and please, subscribe on iTunes, leave us reviews, email us, Tweet at us and help us to move this show fourward! Contact information: Email: fourwards@trinityforcepodcast.com Twitch: twitch.tv/jaxomen, twitch.tv/crushu, twitch.tv/1_witch_1, twitch.tv/freeeshooter, twitch.tv/arkryu, https://www.twitch.tv/slushyotter Tiktok: https://www.tiktok.com/@slushyotter/ Twitters: @4WardsPodcast @jaxomen @slushyotter  

Tommy McNamara (new special SMOLDERING now on YouTube) joins Danny and Tyler once again, this time to talk about legendary songwriter and Queen of Americana, Lucinda Williams. We add her infinitely catchy "I Just Wanted To See You So Bad" to our Official Playlist, and discuss her seminal and untouchable LP Car Wheels on a Gravel Road.For just $5 a month you can help keep the lights on and get access to bonus episodes! Consider supporting us on Patreon HERE!Follow the link below to keep up with which songs are being added to our Ultimate Country Playlist on Spotify, now including "I Just Wanted to See You So Bad," by Lucinda Williams:https://tinyurl.com/takethispodplaylist And on TIDAL!https://t.co/MHEvOz2DOAWant to dive into Lucinda's catalog but don't know where to start? Here are some recs from Tommy and the boys:Something About What Happens When We TalkDrunken AngelChange the LocksCan't Let GoLike a RoseAbandonedPassionate Kisses2 Kool 2 Be ForgottenMetal FirecrackerConcrete and Barbed WireCheck out our Patreon!Check out our new merch store!Instagram: @TakeThisPodandShoveItFor everything else click HERE!Want to create your own great podcast? Why not start today! We use BuzzSprout for hosting and have loved it. So we suggest you give them a try as well! Buzzsprout gets your show listed in every major podcast platform, and makes understanding your podcast data a breeze. Follow this link to let Buzzsprout know we sent you—you'll get a $20 credit if you sign up for a paid plan, and it helps support our show.

In South Carolina, authorities find an elderly couple dead in a home with an astonishing temperature. The government of China proposes regulations on children and gaming. In Hinds county, Mississippi, investigators discover more than 200 people were buried anonymously, with no attempt to contact their families. All this and more in this week's strange news segment.They don't want you to read our book.: https://static.macmillan.com/static/fib/stuff-you-should-read/See omnystudio.com/listener for privacy information.

Folks, Tommy McNamara joins us on this week's episode where we hear about a dog that ate $4k in cash, why potatoes may not be a vegetable after all, a Lord of the Rings restaurant that was shut down, Adam Driver doing two straight movies where he plays an Italian guy, and a man who Britain who hacked the lottery Check out Tommy's new special 'Smoldering' here: youtu.be/ViNPDchxUe4 Become a patron for weekly bonus eps and more stuff!: www.patreon.com/whatatimepodCheck out our YouTube channel: https://www.youtube.com/c/whatatimetobealive Get one of our t-shirts, or other merch, using this link! https://whatatimepod.bigcartel.com/whatatimepod.com Join our Discord chat here: discord.gg/jx7rB7J @pattymo // @kathbarbadoro // @eliyudin // @whatatimepod ©2023 What A Time LLC

Emotional health is closely linked to physical health.

Comedian TOMMY MCNAMARA stops by to talk about his new special Smoldering and the songs of The Bloodhound Gang! The band DINERS perform a live set in the Forever Dog theater and talk NBA with Tom! Phones ring on the topic BEST MOVIE CROSSOVER THAT HASN'T HAPPENED! Another call from ZACH FROM COVERBRIDGE! And the Best Show team throws a surprise birthday party for ZOE but not before learning about the bizarre clinical experiment she's been part of for 22 years and counting! SUPPORT THE BEST SHOW ON PATREON! WEEKLY BONUS EPISODES & VIDEO EPISODES! https://www.patreon.com/TheBestShow WATCH THE BEST SHOW LIVE EVERY TUESDAY NIGHT 6PM PT ON TWITCH https://www.twitch.tv/bestshow4life FOLLOW THE BEST SHOW: https://twitter.com/bestshow4life https://instagram.com/bestshow4life https://tiktok.com/@bestshow4life https://www.youtube.com/bestshow4life THE BEST SHOW IS A FOREVER DOG PODCAST https://thebestshow.net https://foreverdogpodcasts.com/podcasts/the-best-show Learn more about your ad choices. Visit megaphone.fm/adchoices

After a close call, Ann Manheimer had these thoughts about the future of our world.

A new MP3 sermon from DTBM, International is now available on SermonAudio with the following details: Title: ROK-21b - The Four Apocalyptic Horesmen of Doom--Illustrate God's Smoldering Wrath Subtitle: Short Clips - Return Of King Speaker: Dr. John Barnett Broadcaster: DTBM, International Event: Sunday Service Date: 8/23/2023 Length: 6 min.

LAURA When my son asks if I'll rent the spare bedroom to his new friend from work, I figure, why not? The house is too quiet since my twenty-five-year-old baby moved out. I never thought I'd miss the sounds of video games, but apparently, I do. But that's not the background noise I get when Hudson moves in. Turns out, my son's coworker isn't a like-minded gaming geek. Hudson doesn't play video games. He works out. A lot. Now my house is filled with the masculine grunting of a very fit, very handsome, younger man who owns shirts, but isn't inclined to wear them. Ditto for pants. Everywhere I turn in my tiny house, Hudson is there. Flexing. Smoldering. I can't resist looking at him. Or using him for inspiration while I write my current romance novel. Fantasizing about him when I'm lying in my bed. He's my tenant. My son's coworker. A man fifteen years younger than me. Hudson is fodder for my mind, but that's all he can be… until the night he puts every fantasy I've had to shame. HUDSON House hunting is a slow process, and hotel living sucks, so I jump at the opportunity to temporarily rent a room from my coworker's mother. I'm told the place is clean, and the woman is easy to get along with. Perfect. What the guy across the office doesn't tell me? That his mom is ten-out-of-ten hot. Single. And sexual, if the sounds seeping through the paper-thin wall separating our bedrooms are any indication. I'm not a pushy guy, but a man has his limits. Being perpetually hard around her, hearing her moan every night—it's more than I can take. So I make a move. A big one. And it pays off, in the best ways possible. Our chemistry is red hot. We connect outside the bedroom, too. I'm only supposed to be here temporarily, but every minute I spend with Laura makes me determined never to leave. Get the eBook Now: https://amzn.to/3ow8QKU Hope Harbor Series: https://bit.ly/43SlKDi Giveaway: https://bit.ly/41wE2rZ Once Upon a Beast: https://amzn.to/3N1t6hz More Karla Doyle: https://www.karladoyle.com/ ♥ ♥ ♥ RMR Website: https://bit.ly/3ifFIyw Weekly New Release: https://bit.ly/30iDete READ ME ROMANCE - Patreon: https://bit.ly/3IYk16H Follow Read Me Romance on Instagram: https://geni.us/uUVdVeY Join Read Me Romance Headquarters on FB: https://geni.us/IdL7B Read Me Romance Theme Song by L.B. Ballard Podcast Production by Lola

LAURA When my son asks if I'll rent the spare bedroom to his new friend from work, I figure, why not? The house is too quiet since my twenty-five-year-old baby moved out. I never thought I'd miss the sounds of video games, but apparently, I do. But that's not the background noise I get when Hudson moves in. Turns out, my son's coworker isn't a like-minded gaming geek. Hudson doesn't play video games. He works out. A lot. Now my house is filled with the masculine grunting of a very fit, very handsome, younger man who owns shirts, but isn't inclined to wear them. Ditto for pants. Everywhere I turn in my tiny house, Hudson is there. Flexing. Smoldering. I can't resist looking at him. Or using him for inspiration while I write my current romance novel. Fantasizing about him when I'm lying in my bed. He's my tenant. My son's coworker. A man fifteen years younger than me. Hudson is fodder for my mind, but that's all he can be… until the night he puts every fantasy I've had to shame. HUDSON House hunting is a slow process, and hotel living sucks, so I jump at the opportunity to temporarily rent a room from my coworker's mother. I'm told the place is clean, and the woman is easy to get along with. Perfect. What the guy across the office doesn't tell me? That his mom is ten-out-of-ten hot. Single. And sexual, if the sounds seeping through the paper-thin wall separating our bedrooms are any indication. I'm not a pushy guy, but a man has his limits. Being perpetually hard around her, hearing her moan every night—it's more than I can take. So I make a move. A big one. And it pays off, in the best ways possible. Our chemistry is red hot. We connect outside the bedroom, too. I'm only supposed to be here temporarily, but every minute I spend with Laura makes me determined never to leave. Get the eBook Now: https://amzn.to/3ow8QKU Hope Harbor Series: https://bit.ly/43SlKDi Giveaway: https://bit.ly/41wE2rZ Once Upon a Beast: https://amzn.to/3N1t6hz More Karla Doyle: https://www.karladoyle.com/ ♥ ♥ ♥ RMR Website: https://bit.ly/3ifFIyw Weekly New Release: https://bit.ly/30iDete READ ME ROMANCE - Patreon: https://bit.ly/3IYk16H Follow Read Me Romance on Instagram: https://geni.us/uUVdVeY Join Read Me Romance Headquarters on FB: https://geni.us/IdL7B Read Me Romance Theme Song by L.B. Ballard Podcast Production by Lola