Podcast appearances and mentions of edward bullmore

“What if depression isn't just in your head—but in your immune system?” — Dr. Edward Bullmore, The Inflamed Mind What if your depression isn't psychological—but inflammatory? In this explosive episode, we connect the dots between Dr. Edward Bullmore's book The Inflamed Mind and the ongoing mystery of long COVID. We explore how spike protein, chronic immune activation, and persistent inflammation could be driving brain fog, anxiety, and fatigue in millions. This isn't conspiracy—this is cutting-edge science ignored because it makes people uncomfortable. No politics, just biology. And maybe… a path toward healing.

What if the pain you feel in your body isn't just “in your head”—but your head is inflaming your body? Ths episode introduces PSIRS—Psychological Systemic Inflammatory Response Syndrome—a new framework explaining how trauma, grief, and emotional distress can trigger physical inflammation and chronic illness. Drawing on science from The Inflamed Mind by Dr. Edward Bullmore, long-term trauma studies, and ancient wisdom from Dante, Jung, and Nietzsche, this theory outlines a bidirectional loop between the body and mind. Most doctors treat the symptoms. This asks why they keep coming back. If you've ever been gaslit by your own diagnosis, told it's all in your head, or felt like no treatment ever goes deep enough—this is for you. It's time to name the cycle—and learn how to break it. #PSIRS #TraumaHealing #Inflammation #MentalHealthAwareness #MindBodyConnection #ChronicIllness #TheInflamedMind #TraumaInformed #Psychoneuroimmunology #SomaticHealing #AutoimmuneAwareness #AnxietyRecovery #DepressionSupport #HealingJourney #WholeBodyHealing #DanteAndJung #ChronicFatigue #ComplexTrauma #InvisibleIllness #Neuroinflammation

Celiac disease is an unfortunately common autoimmune disorder that affects about 1 in 100 people. That's 1%, a HUGE proportion of the population. What's most concerning is that many aren't ware they have celiac often because many of the symptoms are mental health related and treated solely by psychological means. However, we need to rethink this approach. There's a high correlation between celiac, psychosis (and other mental health concerns such as anxiety, depression, and OCD) and childhood trauma. This is the trifecta that has affected me personally, and many of my clients. So today, I tell you my whole story on finding out and healing autoimmunity and mental health issues. I also discuss: common & lesser known symptoms of celiac why you probably won't notice if you have a gluten allergy why going gluten free isn't always enough what role the nervous system plays in it all emergent research on links between autoimmunity, inflammation and Mental Health Research: - The Inflamed Mind by Dr. Edward Bullmore - https://us.macmillan.com/books/9781250318145/theinflamedmind - Stress & autoimmunity - https://pubmed.ncbi.nlm.nih.gov/29922828/ - Autoimmunity and psychotic disorders - https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00131/full - Childhood stress and autoimmunity - https://pubmed.ncbi.nlm.nih.gov/19188532/ - Gluten psychosis - https://pubmed.ncbi.nlm.nih.gov/26184290/ - Depression and inflammation - https://pubmed.ncbi.nlm.nih.gov/21927805/ - Inflammation and schizophrenia - https://pubmed.ncbi.nlm.nih.gov/26359903/ Disclaimer: The DEPTH Work Podcast is for educational and entertainment purposes only. Any information on this podcast in no way to be construed or substituted as psychological counseling, psychotherapy, mental health counseling, or any other type of therapy or medical advice.

There tends to be a clear distinction between physical and mental health in the way they are both handled and treated but should this distinction be dropped so that they are both simply considered ‘health'? Sean was joined by Edward Bullmore, Professor of Psychiatry at the University of Cambridge and author of 'The Inflamed Mind: A Radical New Approach to Depression'...

There tends to be a clear distinction between physical and mental health in the way they are both handled and treated but should this distinction be dropped so that they are both simply considered ‘health'? Sean was joined by Edward Bullmore, Professor of Psychiatry at the University of Cambridge and author of 'The Inflamed Mind: A Radical New Approach to Depression'...

When we think of a severe mental health crisis, we may think of experiences that get labeled as psychosis, schizophrenia, or other extreme states that require intensive support. But what if these experiences also held rich meaning and opportunity for healing when we can care for them without pathologizing or stripping away autonomy? In this episode you'll hear my personal story of surviving a mental health crisis outside the system, having an intense spiritual awakening, and learning vital lessons about the root causes of mental health concerns. In this episode you'll learn: what it's like to survive an experience of “psychosis” from someone who has lived it why even the most serious mental health crises can be generative how to use multiple frameworks to understand why a mental health crisis happened what autoimmunity, trauma, ancestry, spiritual awakening, and structural oppression all have to do with psychosis and mental health crises Links: 1:1 Holistic Counseling Sessions - https://www.jazminerussell.com/my-practice-1 Breathwork Sessions - https://www.jazminerussell.com/breathwork-sessions Energy Healing Sessions - https://www.jazminerussell.com/energy-healing Research: The Inflamed Mind by Dr. Edward Bullmore (a book about links between immune system and mental health) https://www.goodreads.com/book/show/39899586-the-inflamed-mind Dube, et al(2009). Cumulative childhood stress and autoimmune diseases in adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318917/ Jeppesen, & Benros, (2019). Autoimmune diseases and psychotic disorders. https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00131/full Jordan, Malla & Iyer(2019). “It's Brought Me a Lot Closer to Who I Am”: A mixed methods study of posttraumatic growth and positive change following a first episode of psychosis. https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00480/full Phillips III, Lukoff, & Stone (2009). Integrating the spirit within psychosis: Alternative conceptualizations of psychotic disorders. Read, et al (2005). Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications. https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0447.2005.00634.x Ritunnano, Humpston, & Broome (2021) Finding order within the disorder: a case study exploring the meaningfulness of delusions https://www.researchgate.net/publication/348416655_Finding_order_within_the_disorder_a_case_study_exploring_the_meaningfulness_of_delusions

Research showing that the chemical imbalance theory of mental health is a myth has just hit news cycles again, but this is not the first time this theory has been debunked. Many working in the field have known there is little evidence to support this theory, so why is it only recently the public has been informed? How did this myth originate and where do we go from here? In this episode you'll learn what current research is showing about the lack of evidence for links between depression and serotonin the history behind the chemical imbalance theory and how it became popularized why psychiatrists and people in the field have know the chemical imbalance theory is a myth for years and why the public wasn't informed what this means for antidepressants and psychotropic medication Links: Institute for the Development of Human Arts - http://www.idha-nyc.org/ Research The serotonin theory of depression: a systematic umbrella review of the evidence (Montcrieff et al). https://www.nature.com/articles/s41380-022-01661-0.pdf Time lag in medical science: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241518/ Montcrieff's response to criticism: https://www.madinamerica.com/2022/07/response-criticism-serotonin-paper/ Rolling stones article about fueling right wing media: https://www.rollingstone.com/culture/culture-news/ssri-right-wing-attack-joanna-moncrieff-1388067/ Moncrieff's Response to Rolling Stone article: https://joannamoncrieff.com/2022/08/03/first-they-ignore-you-then-they-ridicule-you-and-then-they-attack-you/ Healing by Thomas insel https://www.thomasinselmd.com/healing Antidepressant effect rates: https://bmjopen.bmj.com/content/9/6/e024886 & https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418603/ Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020392 Other research on chemical imbalance theory & public perception :https://diginole.lib.fsu.edu/islandora/object/fsu:267045/datastream/PDF/view , Books describing history of chemical imbalance theory and over-reliance on pharmaceuticals for mental health treatment The inflamed mind by Dr. Edward Bullmore - https://www.goodreads.com/book/show/39899586-the-inflamed-mind Cracked by James Davies - https://www.simonandschuster.com/books/Cracked/James-Davies/9781639360253 Anatomy of an Epidemic by Robert Whitaker https://robertwhitakerbooks.com/anatomy-of-an-epidemic/

-> O livro «Política a 45 Graus» já está em pré-venda: aqui   Caetano Reis e Sousa é doutorado em imunologia pela Universidade de Oxford e é actualmente Assistant Research Director no Francis Crick Institute, em Londres, onde é também Senior Group Leader do laboratório de investigação em imunologia. A sua investigação centra-se nos mecanismos celulares e moleculares envolvidos na detecção de infecções, cancro e lesões pelo sistema imunitário.  -> Apoie este projecto e faça parte da comunidade de mecenas do 45 Graus em: 45graus.parafuso.net/apoiar A Biologia é de uma complexidade incrível, e o corpo humano é bom exemplo disso. A combinação de órgãos, tecidos, células, moléculas, etc que constitui o nosso corpo não só consegue a proeza de produzir um organismo funcional, como, para a maioria de nós, tirando um ou outro percalço em que precisamos de ir à ‘oficina', o nosso corpo é capaz de desempenhar todas as funções necessárias à vida durante sete, oito ou mesmo mais décadas -- algo que não se pode dizer da grande maioria dos electrodomésticos, carros ou computadores. Por isso, mesmo com os avanços da ciência, há ainda muitos mistérios sobre a Biologia; e mesmo com os progressos na tecnologia, a ‘engenharia natural' continua a estar, na maioria das áreas, muito à frente daquilo que conseguimos criar artificialmente.  Um exemplo óbvio disso é o cérebro: apesar dos progressos na computação, continuamos muito longe de criar algo que se assemelhe a uma inteligência artificial tão abrangente como a mente humana.  E a seguir ao cérebro, o sistema biológico mais complexo que conhecemos é o sistema imunitário. O sistema imunitário é composto por uma rede intrincada de órgãos, células e moléculas que agem em sintonia, em todo o corpo, para nos protegerem de todo o tipo de de vírus, bactérias, fungos e outras agressões que sofremos. A forma como todas as componentes do sistema imunitário interagem entre si -- e também com os outros órgãos e células do corpo -- é tão complexa que ainda não a compreendemos completamente. Ao mesmo tempo, a centralidade do sistema imunitário no corpo de organismos como nós implica que, para respondermos à maioria dessas dúvidas, temos de conseguir responder a questões mais vastas da Biologia e da própria evolução. Esta complexidade é resultado de uma espécie de “corrida às armas” evolutiva: à medida que os organismos se foram tornando mais complexos, foram-se tornando também alvo maior de agentes patogénicos, os quais foram desenvolvendo estratégias cada vez mais variadas. Esta tendência obrigou o sistema imunitário, em particular dos vertebrados, a desenvolver uma complexidade elevada, numa espécie de “corrida às armas evolutiva”.  Caetano Reis e Sousa é a pessoa ideal para compreender melhor o sistema imunitário. Durante a nossa conversa, comecei por pedir ao convidado para explicar como funciona o sistema imunitário. Como veremos, o sistema imunitário dos vertebrados tem duas componentes distintas, que actuam em momentos diferentes. Num momento inicial, quando um agente patogénico entra no corpo, ou sofremos uma lesão, a primeira resposta é dada pelo chamado sistema “inato”. Mas as “armas”, deste sistema 1, são, digamos, pouco diferenciadas -- e isso por vezes não são suficientes para debelar a infecção. Quando isso acontece, entra em funcionamento o sistema 2, que tem uma resposta mais potente e específica para a bactéria, vírus ou fungo em causa. É neste sistema 2, o chamado sistema “adquirido”, que pensamos quando pensamos na resposta imunitária do corpo, por exemplo aos vírus da gripe ou da covid-19. Este sistema 2 tem, ele próprio, duas vertentes que actuam em paralelo para combater a infecção: uma através das células B, que produzem os conhecidos anticorpos para atacar directamente os patogéneos; a outra através das células T, que actuam sobre as células já infectadas.  Embora o sistema imunitário seja, de facto, extremamente eficaz, tem, como todos os sistemas biológicos, falhas e limitações, que também discutimos neste episódio -- com é o caso das alergias, das doenças auto-imunes e mesmo do facto, ainda não totalmente explicado, de irmos perdendo, ao longo do tempo, a imunidade ao vírus da Covid-19 (por razões que ainda não se sabe completamente). Para além de nos proteger de infecções causadas por agentes externos, o sistema imunitário tem também a capacidade de destruir células cancerígenas. Esta vertente do sistema ainda não é totalmente compreendida, mas está na base de uma área de ponta da imunologia que também discutimos: a tentativa de desenvolver vacinas terapeuticas que permitam direccionar o sistema imunitário dos doentes para combater o cancro.  Esta foi, por isso, uma conversa boa para quem, como eu, se interessa por todos os temas, mas também uma conversa com uma componente prática, sobretudo para quem, como eu, tem filhos pequenos. Por exemplo, será que devemos lavar zelosamente as mãos várias vezes ao dia, ou isso impede-nos de ganhar imunidade; será que é possível estimular o nosso sistema imunitário? E a febre, é só uma chatice que devemos baixar com medicamentos, ou tem alguma função em melhorar a resposta do organismo a infecções? Foram estas e outras questões da imunologia que discuti neste episódio com Caetano Reis e Sousa. _______________ Índice da conversa: (07:28) O que é e como funciona o sistema imunitário? (10:10) Como é que o sistema imunitário distingue patogéneos de, por exemplo, bactérias boas ou inofensivas (comensais)? (19:5) Sistema imunitário inato vs adquirido. Células dendríticas ligam os dois sistema.  (23:25) Temos informação imunitária (células T) para todos os patogéneos que podem existir? Células B (produzem anticorpos). Peculiaridades do vírus da (Covid-19) vs vírus da gripe. Quando a resposta imunitária contribui para os sintomas.  (35:44) Como é que uma mutação no vírus pode diminuir a resposta imunitária? (42:14) Há populações com maior imunidade genética do que outras? (46:29) Como é que o sistema imunitário reage ao cancro (e porque não é tão eficaz como a patogeneos)? Vacinas anti-cancro (54:10) Porque, ao contrário da gripe, só somos infectados por varicela uma vez na vida? RSV (57:32) Afinal, devemos andar sempre a lavar as mãos ou é importante expormo-nos, para ganhar imunidade? Edward Jenner and the history of smallpox and vaccination (1:00:16) É possível melhorar o nosso sistema imunitário? (56:44) Porque é que o nosso sistema imunitário enfraquece à medida que envelhecemos? (1:04:31) Transplantes. Primeiro transplante de coração de porco para humano. (1:08:05) Doenças auto-imunes. Ligação à depressão. Livro: The Inflamed Mind: A Radical New Approach to Depression, de Edward Bullmore (1:12:39) Alergias. Intolerâncias alimentares. (1:18:58) Para que serve a febre? _______________ Obrigado aos mecenas do podcast: Julie Piccini, Ana Raquel Guimarães Galaró family, José Luís Malaquias, Francisco Hermenegildo, Nuno Costa, Abílio Silva, Salvador Cunha, Bruno Heleno, António llms, Helena Monteiro, BFDC, Pedro Lima Ferreira, Miguel van Uden, João Ribeiro, Nuno e Ana, João Baltazar, Miguel Marques, Corto Lemos, Carlos Martins, Tiago Leite Tomás Costa, Rita Sá Marques, Geoffrey Marcelino, Luis, Maria Pimentel, Rui Amorim, RB, Pedro Frois Costa, Gabriel Sousa, Mário Lourenço, Filipe Bento Caires, Diogo Sampaio Viana, Tiago Taveira, Ricardo Leitão, Pedro B. Ribeiro, João Teixeira, Miguel Bastos, Isabel Moital, Arune Bhuralal, Isabel Oliveira, Ana Teresa Mota, Luís Costa, Francisco Fonseca, João Nelas, Tiago Queiroz, António Padilha, Rita Mateus, Daniel Correia, João Saro João Pereira Amorim, Sérgio Nunes, Telmo Gomes, André Morais, Antonio Loureiro, Beatriz Bagulho, Tiago Stock, Joaquim Manuel Jorge Borges, Gabriel Candal, Joaquim Ribeiro, Fábio Monteiro, João Barbosa, Tiago M Machado, Rita Sousa Pereira, Henrique Pedro, Cloé Leal de Magalhães, Francisco Moura, Rui Antunes7, Joel, Pedro L, João Diamantino, Nuno Lages, João Farinha, Henrique Vieira, André Abrantes, Hélder Moreira, José Losa, João Ferreira, Rui Vilao, Jorge Amorim, João Pereira, Goncalo Murteira Machado Monteiro, Luis Miguel da Silva Barbosa, Bruno Lamas, Carlos Silveira, Maria Francisca Couto, Alexandre Freitas, Afonso Martins, José Proença, Jose Pedroso, Telmo , Francisco Vasconcelos, Duarte , Luis Marques, Joana Margarida Alves Martins, Tiago Parente, Ana Moreira, António Queimadela, David Gil, Daniel Pais, Miguel Jacinto, Luís Santos, Bernardo Pimentel, Gonçalo de Paiva e Pona , Tiago Pedroso, Gonçalo Castro, Inês Inocêncio, Hugo Ramos, Pedro Bravo, António Mendes Silva, paulo matos, Luís Brandão, Tomás Saraiva, Ana Vitória Soares, Mestre88 , Nuno Malvar, Ana Rita Laureano, Manuel Botelho da Silva, Pedro Brito, Wedge, Bruno Amorim Inácio, Manuel Martins, Ana Sousa Amorim, Robertt, Miguel Palhas, Maria Oliveira, Cheila Bhuralal, Filipe Melo, Gil Batista Marinho, Cesar Correia, Salomé Afonso, Diogo Silva, Patrícia Esquível , Inês Patrão, Daniel Almeida, Paulo Ferreira, Macaco Quitado, Pedro Correia, Francisco Santos, Antonio Albuquerque, Renato Mendes, João Barbosa, Margarida Gonçalves, Andrea Grosso, João Pinho , João Crispim, Francisco Aguiar , João Diogo, João Diogo Silva, José Oliveira Pratas, João Moreira, Vasco Lima, Tomás Félix, Pedro Rebelo, Nuno Gonçalves, Pedro , Marta Baptista Coelho, Mariana Barosa, Francisco Arantes, João Raimundo, Mafalda Pratas, Tiago Pires, Luis Quelhas Valente, Vasco Sá Pinto, Jorge Soares, Pedro Miguel Pereira Vieira, Pedro F. Finisterra, Ricardo Santos _______________ Esta conversa foi editada por: Hugo Oliveira _______________ Bio: Caetano Reis e Sousa é licenciado pelo Imperial College em 1989 e doutorado pela Universidade de Oxford em 1992. Após um pós-doutoramento no NIH, montou seu laboratório em 1998 no ICRF, mais tarde se tornando o Instituto de Pesquisa de Londres do CRUK e agora integrado ao Instituto Francis Crick. Ele ajudou a definir as células e vias envolvidas na detecção imunológica inata de vírus de RNA, fungos e células mortas. Iago da Espada pela sua terra natal Portugal em 2009. Recebeu vários prémios, incluindo o Prémio Louis-Jeantet de Medicina 2017 e o Prémio Bial 2019 em Biomedicina. Ele também é professor de Imunologia no Imperial College e professor honorário da UCL e King's College London e co-fundador da Adendra Therapeutics

مروری بر دلایل بروز افسردگی؛از کوچکترین سلول های مغز ما، تا دوستی های ما______توی این شماره از پادکست سای‌کلیک از دلایل بروز افسردگی گفتم.از اینکه چی میشه که آدما افسرده میشن. دونستن از دلایل بروز افسردگی فقط برای آدمایی که افسردگی رو تجربه می‌کنند نیست، دونستن از افسردگی توی دنیای امروز برای هر کسی لازمه، چون هر آدمی، واقعاً هر آدمی، ممکنه حداقل در دوره‌ای از زندگیش افسردگی رو تجربه کنه، یا حداقل یکی از عزیزان یا دوستان و اطرافیانش دچار افسردگی بشن.اینکه ما از دلایل بروز افسردگی بدونیم نه‌تنها می‌تونیم درک بهتری از شرایط خودمون داشته باشیم که درک بهتری از آدمای اطراف‌مون هم خواهیم داشت. چه‌بسا بتونیم به خودمون و اطرافین‌مون کمک کنیم در مسیر پر پیچ‌و‌خمی که دارند راحت‌تر قدم بردارند.در این پادکست از چند خطای شناختی )خطا در منطق( گفتم که از نظر روانشناسان حوزه روانشناسی شناختی دلایل بروز افسردگی هستند. از این گفتم که دوستی‌ها و روابط عمیق چطور می‌تونن به بهبود افسردگی کمک کنند و چطور می‌تونن پیچیده‌ترش کنن.اگه دوست دارید بدونید داروی افسردگی‌ای که خودتون یا عزیزان‌تون استفاده می‌کنید چکاری انجام میده که افسردگی، رو حداقل برای دوره‌ای، بهبود میده توی این شماره پادکست می‌تونید به زبون ساده ازش بشنوید.گردآوری و تألیف: فروغ فریدونی__________References:So depression is an inflammatory disease, but where does the inflammation come from?:https://pubmed.ncbi.nlm.nih.gov/24228900/.EPA but Not DHA Appears To Be Responsible for the Efficacy of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation in Depression: Evidence from a Meta-Analysis of Randomized Controlled Trials: Journal of the American College of Nutrition: Vol 28, No5: https://www.tandfonline.com/doi/full/10.1080/07315724.2009.10719785.APA Dictionary of psychologyPsychological Science. Michael S.Gazzaniga.The Inflamed Mind, Edward Bullmore.Hubermanlab.com

افسردگی نقطه‌ مقابل سرزندگیبخش اول: تشخیص و نشانه‌هاتوی این قسمت و قسمت‌های بعدی پادکست سای_کلیک به تمام سوالاتی که ممکنه در مورد افسردگی داشته باشید پاسخ میدم و خواهم داد. اینکه چطور بفهمیم آیا اصلاً افسرده هستیم یا اینکه خلق‌پایین و غم‌مون زودگذره و افسردگی نیست. افسردگی دقیقاً چی هست؟ آیا منفعتی هم برای بشر داره؟ نقش تکاملی افسردگی در حیات بشر چیه؟ چرا در بعضی‌هامون به وجود میاد در بعضی دیگه نه؟ آیا همه افسردگی‌ها به یک شکل تجربه میشن؟ و اینکه با افسردگی چه باید کرد؟References:So depression is an inflammatory disease, but where does the inflammation come from?:https://pubmed.ncbi.nlm.nih.gov/24228900EPA but Not DHA Appears To Be Responsible for the Efficacy of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation in Depression: Evidence from a Meta-Analysis of Randomized Controlled Trials: Journal of the American College of Nutrition: Vol 28, No5: https://www.tandfonline.com/doi/full/10.1080/07315724.2009.10719785.Psychological Science. Michael S.Gazzaniga.Lost Connections: Why You're Depressed and How to Find Hope, Johann Hari.The Inflamed Mind, Edward Bullmore.Hubermanlab.com

The Link Between Inflammation and Depression with Prof. Ed BullmoreAir Date Live Streaming on OMTimes TV 1 July at 12:00 PM ET/9:00 AM PT Watch the Livestream on OMTimes Radio & TV Facebook or OMTimesTV YoutubeAir Date OMTimes Radio 8 July at 12:00 ET/9:00 PTTHE INFLAMED MIND: a radical new approach to depression with Prof. Ed BullmoreWorldwide, depression will be the single biggest cause of disability in the next 20 years. but treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still…until now…This week, Rebecca and Sandie talk to world expert in neuroscience and mental health, Professor Edward Bullmore whose game changing bestseller… The Inflamed Mind: A Radical New Approach to Depression reveals the breakthrough new science on the link between depression and inflammation of the body and brain.Prof. Edward Bullmore trained in medicine at the University of Oxford and St. Bartholomew's hospital, London; and then in psychiatry at the Bethlem Royal & Maudsley hospital, London. He moved to Cambridge as Professor of Psychiatry in 1999 and was head of the Department of Psychiatry from 2014-2021. He is currently Director of the Wolfson Brain Imaging Centre, and Deputy Head of the School of Clinical Medicine. He has published more than 500 scientific papers which have been highly cited, and has been elected a fellow of the Royal College of Physicians, the Royal College of Psychiatrists, and the Academy of Medical Sciences.Visit the CRACKED! The Podcast show page https://omtimes.com/iom/shows/cracked-the-podcast/Connect with Sandie Sedgbeer at https://www.sedgbeer.comConnect with Rebecca Schaper at https://www.rebeccaschaper.com/#EdBullmore #TheInflamedMind #RebeccaSchaper #SandieSedgbeer #CrackedThePodcast

È ormai evidente che esiste un nesso tra infiammazione e depressione. In molti pazienti affetti da artrite o da altre malattie infiammatorie, il rischio di depressione aumenta; in molti pazienti colpiti da depressione, invece, aumenta la concentrazione nel sangue delle citochine, le proteine infiammatorie. Ma come è stata interpretata (o screditata) questa connessione dal dualismo cartesiano tipico della medicina occidentale? Alcuni studi dimostrano come e perché l'infiammazione può rientrare tra le cause della depressione. Quali sono i fattori di rischio conosciuti ‒ lo stress sociale, ad esempio ‒ che possono causare infiammazioni? In quale prospettiva futura si potranno utilizzare nuove medicine antinfiammatorie per il trattamento della depressione?

A deep dive into why I've been quiet on the podcast the last couple of months. I got sick with c*vid. In this episode I share every detail with you about my illness process, the lingering effect it has had on my life, and all the supplements and remedies I took/am taking to heal. My personal healing on a mental and physical level has been entirely interconnected, and I am excited to share about a book I've been reading with scientific evidence as to how and why the body and mind are intertwined. Notes:Trigger warning: c*vid, sickness, panic attacks, depression, isolation. As always, please post comments from a space of love and curiosity, never of reactivity or judgement.Book: The Inflamed Mind by Edward Bullmore. Resources:follow us on instagram: @reddustrisingKarli's personal instagram: @astoldbykarliKarli's website: www.karliblalock.comHeart Centered Activism:Here is my site for heart-centered activism: https://www.karliblalock.com/activismGratitude:To Paige Bell @paigebelldesigns for the cover art and title treatmentTo Bryan and Ricky of Slow Cats for the musicSupport the show (https://venmo.com/KarliBee)Like, subscribe, share, follow, rate, review and tell your friends! Support the show (https://venmo.com/KarliBee)

In the second part of our discussion of inflammation and depression with Professor Edward Bullmore we turn towards treatments and prevention. How can inflammation be targeted to treat depression? What are the barriers to this and who should be involved? Could this reduce stigma surrounding depression?

Professor Edward Bullmore, head of the Department of Psychiatry at the University of Cambridge, joins us in the first of two episodes on the relationship between inflammation and depression. We discuss the evidence that inflammation can be a driver of depression, how this relationship might work mechanistically and what this new understanding means for our overall perspective of depression.

Could depression be caused by inflammation?  Cambridge psychiatrist Ed Bullmore makes the case for his radical new theory, from his bestselling book The Inflamed Mind. Here's the breakdown... 6:12 There’s a Cartesian divide in the way we practice medicine.  Professor Bullmore argues that we need to find more integrated ways of treating body and mind. 8:52 The case of Mrs P who was suffering from arthritis and depression. But what was causing what? 12:31 Is this theory a biomedical or psychosocial approach to depression? Professor Bullmore argues that it can bridge the two. 18:07 There will never be just one theory for depression.  19:12 We chat through the enormous range of options on the DSM criterion for depression. Symptoms of depression can include losing weight and gaining weight, sleeping too much and sleeping too little.  21:50 Everyone has a 25% lifetime risk of depression - that’s 1 in every family. 23:11 Why depression may be a bit like fever: one symptom with myriad underlying causes, all of which need different treatments. 25:07 WHAT IS THE EVIDENCE? We finally get around to talking through the different sources of evidence for the Inflammatory theory of depression. Animal studies, longitudinal studies.  27:41 What is ‘inflammation’? 31:00 Can you have inflammation without having any apparent illness or injury? 35:40 Why you might want to try rubbing your auricles. Seriously, it’s nice. 38:47 Is it time to ditch the serotonin theory of depression once and for all? 44:22 Why did the big pharmaceutical companies start abandoning research into psychiatric drugs from 2010? 51:20 New research into the depression-inflammation link is now underway: what’s going on and what are we hoping to find? 54:52 Professor Bullmore shares his aspiration for the next 10 years: to integrate mental and physical healthcare in the way medical are trained and in the way they practice. The Inflamed Mind at Amazon Get in touch with Ilan or join the conversation! You can find NOUS on Twitter @NSthepodcast or on email at nousthepodcast@gmail.com

“Alimentazione e salute mentale”, un libro con uno sguardo diverso su corpo e mente..In questa puntata parliamo dei corpi delle persone con un disturbo psichico; quel corpo che è quasi un rimosso, quando si parla di salute mentale. Corpi che troppo spesso sono vittima degli effetti collaterali di psicofarmaci e di cattivi stili di vita di cui ci si occupa troppo poco, come fossero conseguenze inevitabili del disturbo psichico. Un esempio: alcuni psicofarmaci provocano un forte acquisto di peso, anche 10 o 20 chili, che in breve tempo trasforma il corpo...Marie Francois Delatour, presidente del CUFO (Comitato Utenti, Familiari e Operatori), che riunisce 34 associazione della salute mentale, insieme alla nutrizionista Anna di Muzio, ha scritto un libro dal titolo “Alimentazione e salute mentale”, edito da Pendragon...“Lo spunto principale del libro è stata proprio la preoccupazione dei familiari e dei pazienti rispetto agli effetti collaterali di molti psicofarmaci. - racconta Delatour - Da qui nel 2015 è partito un percorso con l'Azienda USL di Bologna, per migliorare il benessere fisico delle persone con disagio psichico, attraverso piani alimentari, diete personalizzate, attività fisica e un continuo monitoraggio degli obiettivi raggiunti dai singoli pazienti...I risultati sono stati subito evidenti: riduzione del peso, migliore qualità del sonno, un'attività intestinale più regolare e in alcuni casi anche una riduzione delle quantità di farmaci assunti”. Il programma ha coinvolto famiglie, utenti accolti in gruppi appartamento o in altre strutture residenziali; molti all'inizio del progetto non cucinavano mai in casa e spesso non sapevano realizzare neanche le ricette più semplici. Poi “hanno scoperto il piacere di cucinare insieme e anche della convivialità della tavola. Il cibo è diventato lo strumento per stare con gli altri”...“Alimentazione e salute mentale” non insegna solo a mangiare meglio: una parte del libro è dedicata a teorie di cui oggi si sente parlare sempre più spesso, che collegano alcuni disturbi mentali con il sistema immunitario, lo stato di alcuni organi, primo tra tutti l'intestino, ed i livelli di infiammazione presenti nel corpo. Per esempio, viene ricordata la recente traduzione di un libro di Edward Bullmore - neuropsichiatra, neuroscienziato e dal 1999 professore di psichiatria all'università di Cambridge: La mente in fiamme – un nuovo approccio alla depressione, (Bollati-Boringhieri). Il testo inizia con spiegazioni sul funzionamento del sistema immunitario e con risultati di studi secondo i quali l'infiammazione del corpo puo' rientrare tra le cause della depressione (per chi vuole approfondire)...Secondo questo approccio, curare un disturbo psichico non vuol dire solo attenuarne i sintomi, ma prendersi cura del paziente nel suo complesso, corpo e mente - che non sono ambiti così separati.

“Alimentazione e salute mentale”, un libro con uno sguardo diverso su corpo e mente..In questa puntata parliamo dei corpi delle persone con un disturbo psichico; quel corpo che è quasi un rimosso, quando si parla di salute mentale. Corpi che troppo spesso sono vittima degli effetti collaterali di psicofarmaci e di cattivi stili di vita di cui ci si occupa troppo poco, come fossero conseguenze inevitabili del disturbo psichico. Un esempio: alcuni psicofarmaci provocano un forte acquisto di peso, anche 10 o 20 chili, che in breve tempo trasforma il corpo...Marie Francois Delatour, presidente del CUFO (Comitato Utenti, Familiari e Operatori), che riunisce 34 associazione della salute mentale, insieme alla nutrizionista Anna di Muzio, ha scritto un libro dal titolo “Alimentazione e salute mentale”, edito da Pendragon...“Lo spunto principale del libro è stata proprio la preoccupazione dei familiari e dei pazienti rispetto agli effetti collaterali di molti psicofarmaci. - racconta Delatour - Da qui nel 2015 è partito un percorso con l’Azienda USL di Bologna, per migliorare il benessere fisico delle persone con disagio psichico, attraverso piani alimentari, diete personalizzate, attività fisica e un continuo monitoraggio degli obiettivi raggiunti dai singoli pazienti...I risultati sono stati subito evidenti: riduzione del peso, migliore qualità del sonno, un’attività intestinale più regolare e in alcuni casi anche una riduzione delle quantità di farmaci assunti”. Il programma ha coinvolto famiglie, utenti accolti in gruppi appartamento o in altre strutture residenziali; molti all’inizio del progetto non cucinavano mai in casa e spesso non sapevano realizzare neanche le ricette più semplici. Poi “hanno scoperto il piacere di cucinare insieme e anche della convivialità della tavola. Il cibo è diventato lo strumento per stare con gli altri”...“Alimentazione e salute mentale” non insegna solo a mangiare meglio: una parte del libro è dedicata a teorie di cui oggi si sente parlare sempre più spesso, che collegano alcuni disturbi mentali con il sistema immunitario, lo stato di alcuni organi, primo tra tutti l’intestino, ed i livelli di infiammazione presenti nel corpo. Per esempio, viene ricordata la recente traduzione di un libro di Edward Bullmore - neuropsichiatra, neuroscienziato e dal 1999 professore di psichiatria all'università di Cambridge: La mente in fiamme – un nuovo approccio alla depressione, (Bollati-Boringhieri). Il testo inizia con spiegazioni sul funzionamento del sistema immunitario e con risultati di studi secondo i quali l’infiammazione del corpo puo’ rientrare tra le cause della depressione (per chi vuole approfondire)...Secondo questo approccio, curare un disturbo psichico non vuol dire solo attenuarne i sintomi, ma prendersi cura del paziente nel suo complesso, corpo e mente - che non sono ambiti così separati.

“Alimentazione e salute mentale”, un libro con uno sguardo diverso su corpo e mente..In questa puntata parliamo dei corpi delle persone con un disturbo psichico; quel corpo che è quasi un rimosso, quando si parla di salute mentale. Corpi che troppo spesso sono vittima degli effetti collaterali di psicofarmaci e di cattivi stili di vita di cui ci si occupa troppo poco, come fossero conseguenze inevitabili del disturbo psichico. Un esempio: alcuni psicofarmaci provocano un forte acquisto di peso, anche 10 o 20 chili, che in breve tempo trasforma il corpo...Marie Francois Delatour, presidente del CUFO (Comitato Utenti, Familiari e Operatori), che riunisce 34 associazione della salute mentale, insieme alla nutrizionista Anna di Muzio, ha scritto un libro dal titolo “Alimentazione e salute mentale”, edito da Pendragon...“Lo spunto principale del libro è stata proprio la preoccupazione dei familiari e dei pazienti rispetto agli effetti collaterali di molti psicofarmaci. - racconta Delatour - Da qui nel 2015 è partito un percorso con l’Azienda USL di Bologna, per migliorare il benessere fisico delle persone con disagio psichico, attraverso piani alimentari, diete personalizzate, attività fisica e un continuo monitoraggio degli obiettivi raggiunti dai singoli pazienti...I risultati sono stati subito evidenti: riduzione del peso, migliore qualità del sonno, un’attività intestinale più regolare e in alcuni casi anche una riduzione delle quantità di farmaci assunti”. Il programma ha coinvolto famiglie, utenti accolti in gruppi appartamento o in altre strutture residenziali; molti all’inizio del progetto non cucinavano mai in casa e spesso non sapevano realizzare neanche le ricette più semplici. Poi “hanno scoperto il piacere di cucinare insieme e anche della convivialità della tavola. Il cibo è diventato lo strumento per stare con gli altri”...“Alimentazione e salute mentale” non insegna solo a mangiare meglio: una parte del libro è dedicata a teorie di cui oggi si sente parlare sempre più spesso, che collegano alcuni disturbi mentali con il sistema immunitario, lo stato di alcuni organi, primo tra tutti l’intestino, ed i livelli di infiammazione presenti nel corpo. Per esempio, viene ricordata la recente traduzione di un libro di Edward Bullmore - neuropsichiatra, neuroscienziato e dal 1999 professore di psichiatria all'università di Cambridge: La mente in fiamme – un nuovo approccio alla depressione, (Bollati-Boringhieri). Il testo inizia con spiegazioni sul funzionamento del sistema immunitario e con risultati di studi secondo i quali l’infiammazione del corpo puo’ rientrare tra le cause della depressione (per chi vuole approfondire)...Secondo questo approccio, curare un disturbo psichico non vuol dire solo attenuarne i sintomi, ma prendersi cura del paziente nel suo complesso, corpo e mente - che non sono ambiti così separati.

Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... Until now with Edward Bullmore's The Inflamed Mind: A Radical New Approach to Depression. In this game-changing book, University of Cambridge professor of psychiatry Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycles of stress, inflammation, and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how the mind, brain, and body all work together in a sometimes misguided effort to help us survive in a hostile world. His book offers insights into how we could start getting to grips with depression and other mental disorders much more effectively in the future. And I had the pleasure of chatting with him in this episode of The No BS Anxiety Talk Show. ___________________________________ Connect with Edward Twitter: https://twitter.com/edbullmore Buy The Inflamed Mind Amazon: https://amzn.to/2pU4vDf Audible: https://adbl.co/2QUyh64 ___________________________________ Connect with Nicky and The No BS Anxiety Talk Show: Site: https://www.nickycullen.com/ Instagram: https://www.instagram.com/nickycullencom/ Facebook: https://www.facebook.com/nickycullencom/ The No BS Anxiety Support Group: https://www.facebook.com/groups/1188295271319465/

> Sign Up For Our Newsletter: http://www.firsthuman.com/being-human-newsletter/Early in his career, Professor Edward Bullmore, Head of Psychiatry, suffered an infected tooth. During his recovery, Edward felt uncharacteristically depressed. Was he down just because he was dwelling on the misfortune of his sore tooth? Or perhaps - perhaps he was depressed as a direct result of his physical infection. Was his depression actually emerging in his body as it fought the contamination? His idea was heresy within his medical community. As Descartes taught us, the mind is the mind, and the body is the body.In this episode with Professor Bullmore, now Head of Psychiatry at the University of Cambridge, we talk:- The mechanics of how inflammation can cause depression- Why the drugs industry has stalled on new mental drugs - The exciting potential for a new class of mental health drugs - Losing the distinction of 'mental' health. Is it just health?Links: The Inflamed Mind

> Sign Up For Our Newsletter: http://www.firsthuman.com/being-human-newsletter/Early in his career, Professor Edward Bullmore, Head of Psychiatry, suffered an infected tooth. During his recovery, Edward felt uncharacteristically depressed. Was he down just because he was dwelling on the misfortune of his sore tooth? Or perhaps - perhaps he was depressed as a direct result of his physical infection. Was his depression actually emerging in his body as it fought the contamination? His idea was heresy within his medical community. As Descartes taught us, the mind is the mind, and the body is the body.In this episode with Professor Bullmore, now Head of Psychiatry at the University of Cambridge, we talk:- The mechanics of how inflammation can cause depression- Why the drugs industry has stalled on new mental drugs - The exciting potential for a new class of mental health drugs - Losing the distinction of 'mental' health. Is it just health?Links: The Inflamed Mind

> Sign Up For Our Newsletter: http://www.firsthuman.com/being-human-newsletter/Early in his career, Professor Edward Bullmore, Head of Psychiatry, suffered an infected tooth. During his recovery, Edward felt uncharacteristically depressed. Was he down just because he was dwelling on the misfortune of his sore tooth? Or perhaps - perhaps he was depressed as a direct result of his physical infection. Was his depression actually emerging in his body as it fought the contamination? His idea was heresy within his medical community. As Descartes taught us, the mind is the mind, and the body is the body.In this episode with Professor Bullmore, now Head of Psychiatry at the University of Cambridge, we talk:- The mechanics of how inflammation can cause depression- Why the drugs industry has stalled on new mental drugs - The exciting potential for a new class of mental health drugs - Losing the distinction of 'mental' health. Is it just health?Links: The Inflamed Mind

The inflamed mind: a radical new approach to depression

It is thought that depression will be the single biggest cause of disability worldwide in the next 20 years; however, treatment for depression has not changed much in the last three decades. In his game-changing book, ‘The Inflamed Mind: A radical new approach to depression’, Professor Edward Bullmore reveals the breakthrough links found between depression and inflammation of the body and brain, representing a whole new way of looking at how mind, brain and body all work together. Here he discusses this fascinating book with Dr Raj Persaud and outlines a future revolution in the treatment of depression.

Scientists predict that depression will be the largest cause of disability worldwide in the next 20 years. But treatment for it hasn’t changed much in the last three decades. In his new book “The Inflamed Mind: A Radical New Approach to Depression” released on December 31 on Picador, University of Cambridge Professor of Psychiatry Edward Bullmore reveals the link between depression and the inflammation of the body and brain. “The Inflamed Mind” goes beyond the clinic and the lab to examine how mind, brain and body all work together in an often-misguided effort to help us survive in a hostile world. In this installment of “Leonard Lopate at Large” on WBAI, Edward Bullmore discusses the science behind the methodology he outlined in the book.

Andrew Marr starts the year in search of happiness with the behavioural scientist and happiness professor Paul Dolan. Dolan has advised the government on how to measure wellbeing, and in his latest book Happy Ever After argues that we’ve been sold a lie about the sources of happiness. The route to fulfilment may be far more unexpected that we thought. The writer Laura Freeman deplores what she calls the current Pollyana tendencies to ‘keep smiling’ via the mood-tracker apps on your phone. Freeman recounts how she herself found an appetite for life, after years of suffering with anorexia, through her love of reading. The science journalist Linda Geddes explores the impact of sunlight on our minds and bodies. In Chasing the Sun she looks at its significance in improving our health, sleep, productivity and mood. But what if our mood is really affected not by our mind, but our bodies? Professor Edward Bullmore has studied the link between mental health and physical inflammation, and argues that we need to look more closely at our immune system in the treatment of depression. Producer: Katy Hickman

Is depression in the body or the mind? It may seem like a dumb question, but that is really because often we don't know the answer. In some cases depression may be caused by simple inflammation in the body, meaning conventional anti-depressants are useless, and possibly harmful. Professor Edward Bullmore hopes his fascinating new book The Inflamed Mind could be the start of a totally new way of treating depression. It's a really fascinating read. See more at theinflamedmind.co.uk. 

“There is no family in the country that’s going to be untouched by depression” Worldwide, depression will be the single biggest cause of disability in the next 20 years. But treatment for it has not changed much in the last three decades. In the world of psychiatry time has apparently stood still. Up until now, depression has not been considered to be a physical illness but rather something that is all in the mind. In this week’s episode, I talk to world-leading researcher, Professor of Psychiatry and author, Edward Bullmore, about the new science on the link between depression and inflammation of the body and brain. We delve into how and why we now know that mental disorders can have their root cause in the immune system and how identifying the root cause in each individual patient would lead to more effective targeted treatment. Professor Bullmore explains that stress is probably the biggest risk factor for depression and we talk about how lifestyle can be used to combat it. I hope you enjoy the conversation! My upcoming book 'The Stress Solution' is full of actionable tips to help you live a calmer, happier life. You can pre-order it on Amazon.Show notes available at drchatterjee.com/inflamedmindFollow me on instagram.com/drchatterjee/Follow me on facebook.com/DrChatterjee/Follow me on twitter.com/drchatterjeeuk See acast.com/privacy for privacy and opt-out information.

What does your gut health have to do with your mental health and physical health in general?  Functional medicine practitioners, Doctors Tamsin Lewis, Victoria Fenton, and Alberto Pertusa join me today to talk about my latest gut microbiome test results, the links between gut health and mental health, and the importance of gut health to our overall health and wellbeing. Visit https://www.bodyshotperformance.com/podcasts-blog for the complete show notes of every podcast episode. Topics Discussed in this Episode: The links between physical health, particularly gut health, and mental health The GI-MAP and its advantages over other gut microbiome tests What is candida, what are its symptoms, and how we can treat it How often you should get a gut test Gut protocols and gut supplements The gut microbiota-brain axis Key Takeaways: Gut health is absolutely paramount and we can actually prevent lots of things like autoimmune conditions, mental health conditions, as well as physical health conditions by keeping our gut healthy. The GI-MAP is an advanced form of testing the gut, which looks at the DNA of various pathogens in the gut as well as gut health markers. Candida can be totally asymptomatic, but one of the most common symptoms is sugar cravings and people not being able to regulate their sugar consumption. No gut protocol comes without consequences because we’re treating bacteria. Gut supplements are either supporters or treatments, and they sometimes cross over. Biofilms are the reason why gut issues remain. They can cover over the bacteria and basically protect them from your own immune system. There’s a common misnomer that excess acidity in the gut causes reflux and causes problems with digestion. It’s actually impaired production of acid that often makes things worse. Stress is one of the biggest things that affect gut health. It a bidirectional relationship -- stressed guts create stressed people and vice versa. Systemic inflammation, which is inflammation in the body and potentially the brain, is linked with potentially all mental conditions but the evidence is more for depression. Any protocol that potentially improves gut health could directly or indirectly improve mental health. Action Steps: Get a gut microbiome test, particularly the GI-MAP. Look at your gut microbiome in the context of you and how you feel, how your gut feels, how your energy feels and how your weight is. Tamsin Lewis said: “The bugs in the gut actually speak via the gut-brain axis. They actually speak to the brain via the nerves… there’s sort of the sickening process going on that these little things in the gut are waving via various neural mechanisms and then changing how you feel and function.” Victoria Fenton said: “These gut bugs can, to a certain extent, drive behaviour, because they need their food and their intake and they will actually be able to ask you to do that. It sounds nonsense, but actually, it can drive your cravings and it can change the way you want to select your food.” Alberto said: “What happens in the gut may actually be playing a significant role in what happens in the brain.” Thanks for listening! If you’re interested in finding out what your health IQ is, take the Health IQ test to find out, and get a free 39-page report built around our six signals, which are sleep, mental health, energy, body composition, digestion, and fitness. If you’ve enjoyed what you’ve heard on this episode and it’s added value to you, share the episode with someone you think could benefit from it. And don’t forget to leave a rating or a review and subscribe on Apple Podcasts. Links to things we discuss in the show: YouTube link to this episode Gut supplements: GastroMend Biocidin Liquid The Inflamed Mind: A Radical New Approach to Depression by Edward Bullmore Lesley Paterson More from Dr. Tamsin Lewis: Fibr Dr. Tamsin Lewis’ Website (SportieDoc) Dr. Tamsin Lewis’ Twitter (@SportieDoc Dr. Tamsin Lewis’ Instagram (@sportiedoc) More from Dr. Victoria Fenton: Fibr Dr. Victoria Fenton’s Website More from Dr. Alberto Pertusa: Dr. Alberto Pertusa’s Website Dr. Alberto Pertusa’s Twitter (@PsychiatristLDN) More from Leanne Spencer: Bodyshot Performance Bodyshot Performance Limited Facebook page Remove the Guesswork BOOK by Leanne SpencerRise and Shine BOOK by Leanne Spencer   Leanne’s Email

Leading professor of psychiatry Edward Bullmore introduces breakthrough new science on the link between depression and inflammation of the body and brain. Going beyond the clinic and the lab, Professor Bullmore presents a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. Offering insights into the story of Western medicine, he shows how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future. This event was recorded live at The RSA on Thursday 10th May 2018. Discover more about this event here: https://www.thersa.org/events/2018/05/a-new-approach-to-depression