Podcasts about Reis

In this episode of the Longevity Optimization Podcast, Dr. Carolina Reis Oliveira, co-founder and CEO of OneSkin, shares her journey in stem cell biology and the development of innovative products focused on skin and hair health. With a PhD in immunology and a background in stem cell and tissue engineering, Dr. Carolina leads OneSkin's research and development efforts to create molecules that target cellular aging, including the groundbreaking OS-01 peptide.OneSkin is a biotechnology company founded in 2016 and based in Silicon Valley, focused on developing anti-aging skin and hair products. Under Dr. Carolina Reis Oliveira's leadership, OneSkin aims to delay the onset of age-related diseases by targeting cellular aging mechanisms. Their flagship innovation, the OS-01 peptide, is scientifically designed to reduce senescent cells, promoting skin and hair health at a molecular level. The company combines cutting-edge research with practical applications to create products that support longevity and wellness.Save On OneSkin Hair Here: oneskin.co/KAYLALet's be friends!Instagram: https://www.instagram.com/kaylabarnes/?hl=enTikTok: https://www.tiktok.com/@femalelongevityX: https://x.com/femalelongevityWebsite: https://kaylabarnes.comJoin Female Longevity Community: https://kayla-barnes-lentz.circle.so/checkout/become-a-memberFollow One Skin:Instagram: https://www.instagram.com/oneskin.co/?hl=enTikTok: https://www.tiktok.com/@oneskin.coTimestamps00:00 Introduction to Longevity and Skin Health02:50 Understanding Hair Biology and Growth Phases07:00 Root Causes of Hair Loss10:10 Addressing Hair Loss: Diagnosis and Treatments12:03 Current Hair Loss Products and Their Limitations17:12 Innovative Solutions: OS1 Hair Product Development20:51 Clinical Study Results and Efficacy of Hair Treatments24:22 Combining Therapies for Optimal Hair Health25:03 Scalp Care and Hair Washing Practices28:24 Understanding Scalp Health and Microbiome33:55 Preventative Measures for Hair Loss39:57 Innovative Approaches to Hair Thinning46:18 The Science Behind Peptides and Hair Care

On this episode of The Wholesome Fertility Podcast, I am joined by Dr. Nirali Jain (eggspert_md), a board-certified OB/GYN and reproductive endocrinologist at Reproductive Medical Associates (RMA). Dr. Jain shares her expert insights on fertility preservation for individuals undergoing cancer treatment, a crucial yet often overlooked aspect of reproductive care. We explore what options are available for fertility preservation, including egg and sperm freezing, and why it's so important to initiate these discussions before starting chemotherapy or radiation. Dr. Jain also explains the difference between Letrozole and Clomid, the impact of estrogen-sensitive cancers on IVF treatments, and innovative approaches like random-start cycles and DuoStim protocols. Whether you're facing a cancer diagnosis or simply thinking proactively about your reproductive future, this conversation is filled with knowledge and reassurance. Key Takeaways: Why it's essential to discuss fertility before starting cancer treatment. The role of Letrozole in estrogen-sensitive cancers and fertility preservation. Differences between Letrozole and Clomid, and why Letrozole is often preferred. How new protocols like DuoStim and random-start cycles are improving outcomes. Why fertility preservation is important even for those without a cancer diagnosis. Guest Bio: Dr. Nirali Jain (@eggspert_md) is a board-certified OB/GYN and fertility specialist at Reproductive Medicine Associates (RMA) in Basking Ridge, New Jersey. She earned both her undergraduate degree in neurobiology (with a minor in dance!) and her medical degree from Northwestern University, before completing her residency at Weill Cornell/NYP, where she served as co-Chief Resident, and her fellowship in reproductive endocrinology and infertility at NYU Langone. Deeply passionate about women's health and fertility preservation, Dr. Jain blends the latest research and cutting-edge treatments with compassionate, patient-centered care. Her interests include third-party reproduction and oncofertility, and she is especially passionate about supporting patients navigating fertility preservation through a cancer diagnosis. Outside of the clinic, Dr. Jain is a trained dancer, a dedicated global traveler, and an adventurer working toward hiking all seven continents with her husband. Her diverse experiences, from international medical rotations to personal connections with friends and family navigating infertility, have shaped her into a warm, resourceful, and determined advocate for her patients. Links and Resources: Visit RMA websiteFollow Dr. Nirali Jain on Instagram For more information about Michelle, visit www.michelleoravitz.com To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. --  Transcript:   # TWF-Jain-Nirali (Video) ​[00:00:00]  **Michelle Oravitz:** Welcome to the podcast Jain.  **Dr. Nirali Jain:** Thanks so much for having me **Michelle Oravitz:** Yeah, so. **Michelle Oravitz:** I'm very excited to talk about this topic, which, um, actually you don't really hear a lot of people talking about, which is how to preserve your fertility if you're going through a cancer diagnosis and if you have to go through treatments. 'cause obviously that can impact a lot on fertility. **Michelle Oravitz:** I have, um, seen actually like a colleague of mine go through. And she also preserved her fertility and, and now she has a baby boy. so it's really nice. **Michelle Oravitz:** to **riverside_nirali_jain_raw-video-cfr_michelle_oravitz's _0181:** so nice. **Michelle Oravitz:** So I'd love for you first to introduce yourself and kind Of give us a background on how you got into this work. **Dr. Nirali Jain:** Of course. Um, so I am Dr. Narly Jane. I am, um, an OB GYN by training, and then I did an additional, after completing four years of residency in OB GYN and getting board certified in that, I did an additional training in reproductive endocrinology and [00:01:00] infertility or otherwise known as REI. So now I'm a fertility specialist. **Dr. Nirali Jain:** Um, I trained at Northwestern in Chicago, so I went to undergrad and medical school there. And then, um, home has always been New Jersey for me, so I moved back out east to New Jersey. Um, I did all my training actually in New York City at Cornell for residency and NYU for fellowship. Um, and then moved to the suburbs. **Dr. Nirali Jain:** Um, and now I'm a fertility specialist in, in Basking Ridge at Reproductive Medical Associates.  **Michelle Oravitz:** Very impressive background. That's awesome.  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** I'd love to hear just really. About what your process is. If a person has been diagnosed with cancer, like what is the process? What are some of the things that you address if they are trying to preserve fertility, and what are some of the concerns going  **Dr. Nirali Jain:** yeah, yeah. All great questions. So, you know, there's a lot of us, uh, the Reis. Are a very small, [00:02:00] there's a very small number of us. So in terms of specializing in fertility preservation, technically we all are certified to treat patients with cancer and kind of move them through fertility preservation before starting chemotherapy. **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** Um, luckily we've been working closely with oncologists in the past several years just to establish some type of streamlined system because having a diagnosis of cancer and hearing all that information. Especially when you're young is so hard. So I think that's, that's where my interest started in terms of being able to speak to and counsel cancer patients. **Dr. Nirali Jain:** I think it is a very specific niche that you really have to be comfortable with in our field. Um, I. So I'll kind of walk you through, you know, what it, what does it look like, right? Um, you go into your oncologist's office suspecting that you have this, this lump. I'll take breast cancer, for example. It could really be any kind of cancer. **Dr. Nirali Jain:** Um, but breast cancer in a reproductive age patient or someone that's in those years where you're starting [00:03:00] to think about building a family, planning a family, um, or if you have kids at home, that's usually the type of patient that we see come in with a breast cancer diagnosis. So. Kinda just taking that, for example, um, the minute that you're diagnosed, it's really your oncologist's responsibility to counsel you on what treatment options are going to be offered to you. **Dr. Nirali Jain:** And then based off of the treatment options, it's important to know how that affects your reproduction. So how does it affect your ovaries in the short term, in the long term, um, in any way possible. So. Once a patient is initially referred from their oncologist to myself or any other fertility specialist, they come into my office and we just have a 30 minute conversation really talking about family planning goals. **Dr. Nirali Jain:** Any kids that they've had in the past either naturally conceived or through um, IVF, and then we talk about where they're at in their relationship. Are they married, are they not? Are they with a partner, [00:04:00] a male partner, a female partner, whatever it might be. It's important to know the social standpoint, um, especially in this sensitive phase of life. **Dr. Nirali Jain:** So patient patients usually spend anywhere from 30 minutes to an hour. Um, just kind of talking through where they're at, how they're feeling, what their ultimate childbearing goals are. And then from there we do an ultrasound and that's when I'm really able to see, you know, the, the reproductive status. **Dr. Nirali Jain:** So what do the ovaries look like? What does the uterus look like? Is there something that I need to be concerned about from a baseline GYN standpoint? Um, and all of those conversations are happening in real time. So. I think one of the things is patients come in and they're like, I'm already so overwhelmed with all this information from my oncologist, and now my fertility specialist is throwing all this information at me. **Dr. Nirali Jain:** Luckily, the way I like to frame it is you come in and you just let go. Like you let us do the work because in the background we're the ones talking to your oncologist. We're the [00:05:00] ones giving that feedback and creating a timeline with your oncologist. Um, and really I think just getting in the door is the hardest part. **Dr. Nirali Jain:** So once patients are here to see us, we go through the whole workup. We do anything that we would do for a normal patient that came in for fertility preservation. And then based off of where they're at in their journey, we talk about what makes sense for them, whether that means freezing embryos, freezing eggs, they're very similar in terms of the, the few weeks leading up to the egg retrievals. **Dr. Nirali Jain:** So I have that whole conversation just at the initial visit. And then from there we talk about the timeline behind the scenes and make sure that it works with their lives before moving forward. **Michelle Oravitz:** So for people listening to this, why, and this might be an obvious question, but to some it might not be,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** why would somebody want to preserve. eggs or sperm. 'cause I've had actually some couples  **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** come to me where the husband preserved the sperm and they had to go through IVF just because he was going [00:06:00] through cancer treatments. So he had to preserve the sperm ahead of time.  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** people need to consider doing that before doing cancer treatments?  **Dr. Nirali Jain:** So there are certain cancer treatments that do affect the ovaries and the sperm health, and you know, for men and women, it affects your reproductive organs. In a similar way, um, depending on the type of chemotherapeutic agent, there are some that are more dangerous in terms of, um, being toxic to your ovaries or toxic to your sperm. **Dr. Nirali Jain:** And those are the instances where we are really thinking about what's the long-term impact because there's medications that oncologists do give patients, and our oncologists are amazing, the ones that we work with, Memorial Sloan Kettering from Reproductive Medical Associates through RMA, um, and. **Dr. Nirali Jain:** They're just so good at what they do and are so well-trained, so they know in the back of their mind, is this going to impact your ovaries or your sperm health or not? Um, and I [00:07:00] think that any chemotherapy, you know, your ovaries are these, these small organs that are constantly turning over follicles every month. **Dr. Nirali Jain:** So every month we're losing those eggs, and if they don't become. If an egg isn't ovulated, it doesn't become a baby, it's just gonna die off. So I counsel even patients that don't have cancer, I counsel them on fertility preservation as young as possible. You know, between the ages of 28 and 35, that's like the best time to preserve your fertility. **Dr. Nirali Jain:** So in cancer patients, there's an extra level added to that where even if they are a little bit younger, a little bit older. Your eggs are not gonna be the same quality. There's gonna be higher level of chromosomal errors, more DNA breakage, um, and, and bigger issues that lead to issues with conceiving naturally afterwards. **Dr. Nirali Jain:** So I think that it's important to consider how that chemotherapy is going to affect them or how surgery would affect them if it was, for example, a GYN cancer where [00:08:00] we're removing a whole ovary, you know, what, what do we have to do to preserve your fertility in that case? And those are important conversations to have. **Michelle Oravitz:** Yeah. for sure. I know that a lot of people are also concerned, you know, with going through the IVF process, you're taking in a lot of estrogen, a lot of hormones, and many cancers are actually estrogen sensitive. So I wanted to talk to you about that. 'cause I know that the data shows that it's. It's been fine, which some people might find surprising, but I wanted you to address that and just kind of **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** from your perspective.  **Dr. Nirali Jain:** That's so interesting that you asked that question because I actually, my whole I I graduated fellowship last year and my entire, like passion project in fellowship was looking at one of the drugs that we use to suppress the estrogen levels specifically in cancer patients. Um, and I had presented this at a few of our reproductive meetings. **Dr. Nirali Jain:** Um, A SRM is one of our annual meetings where all of the reiss get together. A lot of male fertility [00:09:00] specialists come and we kinda just talk about. Specific things and fertility preservation for cancer patients is, has been an ongoing topic of interest for all of us. Um, and it's important to know that there are different medications that we can offer. **Dr. Nirali Jain:** Letrozole is the one that I, um, have a particular love for and I, uh, you know, I use all the time for my patients, um, for different reasons, but it suppresses the exposure that your body has to estrogen. And there's mixed data, um, out there in terms of, you know, does Letrozole suppression actually impact, you know, does it help or. **Dr. Nirali Jain:** Or does it have no impact on your future risk of cancer after treatment? Um, and that honestly is still up for debate. But what we do know is that there's no increased risk of cancer recurrence in patients that have undergone fertility preservation with or without Letrozole. Um, Letrozole is one of those things that we can give, and the way it works is basically. **Dr. Nirali Jain:** It masks that [00:10:00] conversion. It, it doesn't allow for conversion from those androgens in the male hormones over to estrogen. Um, and so your body doesn't really see that estrogen exposure. It stays nice and low throughout your cycle, and it does help with actually ovarian maturation and getting mature eggs harvested and, um, helps a little bit with, with quality too. **Dr. Nirali Jain:** So I think that it's really nice in terms of having that available to us, but know that. It's not, it's not essential that you have it, really, the data showing plus minus. Um, but there are certain things that we can do to protect the ovaries, protect your exposure to estrogen. Um, and so that shouldn't be top of mind of concern when we're going through fertility preservation, even with an estrogen sensitive cancer. **Michelle Oravitz:** Actually, so, uh, on a different topic, kind of going back to that, so Letrozole versus Clomid, I, it's like a, the questions I personally feel just based on what I've heard and like my own research that Letrozole would be kind of like the more. [00:11:00] Um, the, it's, it's a little better, but I know that it really depends on the person as well.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** they might do better with Clom, but I'd love to hear your perspective and kind of pick your brain on this.  **Dr. Nirali Jain:** totally. You're choosing all the, all the right questions because these are all of my, my specific interests and niches. So  **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** Letrozole is basically, you know, we use Letrozole and Clomid in. Patients that don't have cancer and patients that come in for an intrauterine insemination, that's kind of the most common scenario where we're thinking about, you know, which medication is better? **Dr. Nirali Jain:** Letrozole or Clomid and Clomid used to be the, the most common medication that we use, we dose patients, you know, have 50 milligrams of Clomid, give them five days of the medication. It's an oral pill. Feels really easy and. The way it works is really, it recruits more than one follicle, so it really helps with the release of, um, more than one follicle growing more than one follicle in the ovary. **Dr. Nirali Jain:** Um, but it has a little bit [00:12:00] higher of a risk of twins because that's exactly what it's good at. Um, Clomid, not so much in the cancer. In the cancer front, it's not really used there because it's considered, from a scientific perspective, it's considered like a selective estrogen receptor modulator. So it doesn't necessarily suppress your estrogen levels in the same way that Letrozole does versus. **Dr. Nirali Jain:** Letrozole is an aromatase inhibitor, so it really blocks the chemical conversion of one drug or one hormone to the other hormone. Um, the reason we love Letrozole so much, and I don't mean to like gush over Letrozole, but um, it's a mono follicular agent, so it works really well at recruiting one follicle  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** you know, every OB-GYN's nightmare in a way is having multiples when you didn't intend on having multiples at all. **Michelle Oravitz:** so  **Dr. Nirali Jain:** Um. **Michelle Oravitz:** were saying that, um, there's more of a chance of twins, it's Clomid, not letrozole.  **Dr. Nirali Jain:** Yes, there's a higher chance with Clomid versus Letrozole. And I mean, don't get me wrong, there's a chance of twins with [00:13:00] any type of assisted reproductive technology. Even when we're doing single embryo transfers, there's a chance that it's gonna split. So, um, the chance is always there just like it is in the natural world. **Dr. Nirali Jain:** But we know for a fact that. CLO is really good at recruiting many follicles. It's good for certain patients that don't respond well to Letrozole. Um, but Letrozole is kind of our, our go-to drug these days just because of all the benefits that we've seen.  **Michelle Oravitz:** Awesome.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** These are all fun things to ask because I, I love talking to our eis 'cause there's so much information that I'm always  **Dr. Nirali Jain:** totally. **Michelle Oravitz:** learn a lot from my patients in my own research, but it's really cool. Picking your guys' brains. So another question I have, and I have actually talked to Dr. Andrea Elli, he's been on,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** and he does a lot of endometriosis and, and immune related work as well,  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** so. I'd love to know just from your perspective. One thing that I do know from, based on what I've heard is that the, [00:14:00] guess like you were just saying, that breast cancer or estrogen sensitive breast cancer doesn't seem to be affected by IVF cycles, however, and endometriosis lesions do get affected.  **Dr. Nirali Jain:** Yeah. **Dr. Nirali Jain:** that's a great question. So, you know, every, there are so many complex G mind diagnoses that the, that our patients come in with. Um, and endometriosis is a big one because there is clear data that endometriosis is linked to infertility. So we think about, you know, when a patient comes in with endometriosis, we really do think about the different treatment options and what are the short-term and long-term impacts of the hormones that we're giving 'em. **Dr. Nirali Jain:** Um, these days, again, kind of going back to Letrozole, we, letrozole is something that I give all of my endometriosis patients because it helps suppress their estrogen because we know.  **Michelle Oravitz:** interesting.  **Dr. Nirali Jain:** is very responsive to estrogen and leads to this dysfunctional regulation of all the endometrial tissue that can really flare in a, [00:15:00] in a cycle, or shortly after a cycle. **Dr. Nirali Jain:** I. So we really, for endometriosis patients, the, the best treatment is being on birth control because we don't see that hormonal fluctuation. The up and down of the estrogen and the progesterone, that's what leads to those flares. Um, so I really, I watch patients closely after their cycles too, because you definitely can have an endometriosis flare and we say the best treatment for endometriosis is pregnancy, right? **Dr. Nirali Jain:** That's when you're suppressed, that's when you're at your lowest. Um, and patients, my endo patients feel so good in pregnancy because they have. Hormones that are nice in that baseline, they're not getting periods of course. Um, and that's truly, truly the best treatment.  **Michelle Oravitz:** That's interesting.  **Dr. Nirali Jain:** But it is important to consider when you're going through infertility treatments. **Dr. Nirali Jain:** How does my endometriosis affect the short and long-term effects of the fertility medications? And really not to, not to say that they're bad in any way. I think a lot of endometriosis patients go through IVF and have success and do really, really well, and that's kind of the push that they need. [00:16:00] Um, but it's important to be mindful of the bigger picture here. **Dr. Nirali Jain:** It's not just, you're not just a number of. A patient with endo coming in, getting the same protocol. It's really individualized to the extent of your lesions, what symptoms you're having, what grade of endometriosis, where your lesions are. So we're the RAs are thinking about everything before we actually start your protocol. **Michelle Oravitz:** It's crazy how in depth it is, and it's, it, there's just so, it's so multifaceted,  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** when it's females  **Dr. Nirali Jain:** totally. **Michelle Oravitz:** are a little, I mean, they can, you know, there, there's definitely a number of things, but it's not as complicated and interconnected  **Dr. Nirali Jain:** Exactly. Exactly. That's so true. **Michelle Oravitz:** And so one question I actually have, this is kind of really off topic, but something that I was curious about. **Michelle Oravitz:** 'cause I heard about a while  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** a, a type of cancer treatment that was used. I'm not sure exactly what it was, but for some reason it actually caused follicles to grow, [00:17:00] or to multiply. And they were **Dr. Nirali Jain:** Interesting. **Michelle Oravitz:** this definitely. Puts, um, the whole idea of like a woman being born with all the follicles she'll ever have on its head, I thought that was really Interesting. **Michelle Oravitz:** Now I learned a little bit about it. I don't think it really went further than that,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** one of those things that they're like, Hmm, this is interesting. I don't know, it was kind of a random side effect of this chemo drug. I dunno if it was a chemo drug or a cancer drug.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** ever heard of that. **Michelle Oravitz:** So I was just **Dr. Nirali Jain:** I haven't, I mean, that's interesting. I feel like I'd have to look into that because that would be definitely a point of interest for a lot of Reis. But it kind of does go back to the point of, you know, women are really born with all the eggs we're ever gonna have. So it's about a million, and then it just goes down from there. **Dr. Nirali Jain:** And the, by the time you start having periods, I like to kind of show my patients a chart, but you have a couple hundred thousand eggs and you ovulate one egg a month. That's, you know. Able to [00:18:00] progress into a fertilized egg and then into a, an embryo into a baby, um, if that's your goal. But otherwise, patients that are having periods and not trying to actually get pregnant, we're losing hundreds of eggs a month. **Dr. Nirali Jain:** So.  **Michelle Oravitz:** Mm.  **Dr. Nirali Jain:** It's important to kind of think about that decline, and it's important to know that that rate can be faster in patients with cancer, patients with low ovarian reserve. And sometimes when you have the two compounded, that's when a fertility specialist is definitely, you know, in the queue to, to have a discussion with you in terms of what that means and how you can reach your family building goals despite being faced with that, with that challenge. **Michelle Oravitz:** Yeah. **Michelle Oravitz:** I mean, 'cause we know oxidative stress is one of the things that can cause, uh,  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** quality eggs, but it's also can cause cancer. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** um, similar, you know, like things that really deplete the body could definitely impact. Um, and then what are your thoughts? I know I'm asking you all kinds of random questions, **Dr. Nirali Jain:** I love it. **Michelle Oravitz:** are your thoughts about doing low simulation in certain [00:19:00] circumstances versus high stem? **Michelle Oravitz:** Sometimes people don't respond as well to higher stems.  **Dr. Nirali Jain:** Yeah, that's a great point. I think that it kind of all goes back to creating an individualized protocol. If. A patient's going to a practice and basically just getting a protocol saying, this is our standard. We start with our standard of, you know, I, I think about the standard, which is 300 of the FSH or that pen that you dial up, and then 150 units of that powder vial. **Dr. Nirali Jain:** And we have patients mixing powders all the time, and that's kind of our blanket protocol that we give patients. But that's not really what's happening behind the scenes. And if you're given a protocol that's, and being told, you know, this is kind of what we give to everyone, it's probably not the right fit for you. **Michelle Oravitz:** Yeah, I  **Dr. Nirali Jain:** Um, there are certain patients that respond to a much lower dose and do really, really well, and then some patients that need a much higher dose. Um, and I think it's, that's kind of like the fun part of being an REI of being able to individualize the [00:20:00] protocol to the patient. Um, and I know for a fact there are so many, luckily, you know, we have so many leaders in REI that have been. **Dr. Nirali Jain:** Have dedicated their entire careers to researching these different protocols and how they can help different patients. Um, patients with lower a MH, you know, might benefit from a duo stim protocol, for example. That's kind of the first one that comes to mind, but a protocol where we're using those follicles from the second half of a cycle. **Dr. Nirali Jain:** I would've never thought that those were the follicles that  **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** would be better than the first half of the cycle,  **Michelle Oravitz:** Wait,  **Dr. Nirali Jain:** but, **Michelle Oravitz:** that. Explain that. Um, because I think that that's kind of a unique  **Dr. Nirali Jain:** mm-hmm.  **Michelle Oravitz:** that I haven't heard of.  **Dr. Nirali Jain:** Yeah, so there's this new day. It's still kind of developing, but um, kind of going back to, you know, what's an individualized protocol? Duo STEM is one of the newer protocols that we've started using. I, I've used it once or twice in patients. Um, but it goes back to the research that shows that you might actually have two different periods of time in a menstrual cycle where you could potentially recruit [00:21:00] follicles. **Dr. Nirali Jain:** You could have a follicular phase where there's a certain cohort of follicles recruited, and then you have a follicle that forms creates a corpus glut.  **Michelle Oravitz:** um, protocols  **Dr. Nirali Jain:** Yep. And then you basically go through the follicular protocol and then a few days after a retrieval, instead of waiting for a new follicular cohort or follicular recruitment from the first half of your menstrual cycle, you actually use the luteal phase and you recruit those follicles that would've actually died off or have been prematurely recruited in a prior cycle. **Dr. Nirali Jain:** So **Michelle Oravitz:** that's So  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** you just do a similar, I guess, um, medicine,  **Dr. Nirali Jain:** go right back into it.  **Michelle Oravitz:** do the same exact thing, but right after ovulation.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** Fascinating. That's really interesting.  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** has been your experience with that?  **Dr. Nirali Jain:** I think it's, honestly, it's mixed. Um, so far, you know, our data from fertility and sterility and A SRM, it, it shows support for these DUO STEM [00:22:00] protocols, saying that if patients don't have that great quality of eggs or if they have a very low number, maybe they'd benefit from starting the meds earlier and recruiting follicles. **Dr. Nirali Jain:** A little bit earlier. Um, so we've seen positive results so far. A lot of work to be done in terms of really understanding it. Um, and of course, as a new attending, I have a lot more experience to kind of build on. Um, but I, I have seen success from it. **Michelle Oravitz:** That's fascinating. Are there any other new technologies, like new add-ons, um, that you've seen, that you've found to be really cool or interesting?  **Dr. Nirali Jain:** I think the biggest thing, actually, kind of going back to our whole topic for today is fertility preservation cancer patients. One of the biggest things that I've learned recently is that we used to start fertility, um, patients. You know, only in the beginning of the cycle days, two or three is technically like when most. **Dr. Nirali Jain:** Most clinics, um, start patients, but for our cancer patients, sometimes you don't have that time. You don't wanna wait a full month to [00:23:00] restart, um, your, you know, your menstrual cycle and then do the fertility preservation and then delay chemotherapy a full month. So we started doing what we call random starts. **Dr. Nirali Jain:** So you basically start a patient whenever they come in. You know, it could be the day after your consultation, the day of your consultation. I've kind of seen all of the above. Um, and we've seen really good success with random starts, per se. Um, and we've been doing a lot more of that, where it's not as dependent on where you're at in your cycle. **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** Um, obviously there's a difference in outcomes. You might not be a great candidate for it, so definitely it's worth talking to your doctor about it. But it kind of gives relief to our cancer patients where if you have a new cancer diagnosis and you're like, oh, I just finished my period, like, I can't even start a cycle until next month. **Dr. Nirali Jain:** That's not always true. Um, so it's always worth it to go into see a fertility specialist and just get, you know, get the data that you need right away, and then you can make a decision later on. **Michelle Oravitz:** For sure. Um, Yeah. **Michelle Oravitz:** and I wanted to kind of cover a lot of different topics 'cause I know that [00:24:00] some people are gonna wanna hear what you have to say that don't necessarily, or, uh, have cancer. But it is important. I, I think that, you know, if you get to thirties and you haven't gotten married or you don't have a partner, I think it's really important to preserve your fertility in general.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** important thing. And then if you were going through a cancer diagnosis and you decided to preserve your fertility, um, guess more for women because they're eventually going to be thinking about transfers after they go through treatment. So what are some of the things that they would need to consider as far as that goes? **Michelle Oravitz:** Like after the  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** then they go through the cancer treatments. Um, and then what, how long should they  **Dr. Nirali Jain:** yeah. Like what does it look like? So I've had patients that come back, you know, in my fellowship training I did a, a couple research projects on patients that came back to pursue an embryo transfer, um, after chemotherapy agent. And basically compared them to how they did, um, [00:25:00] compared to patients that didn't have cancer and just froze their embryos or froze their eggs and then came back to pursue a transfer and. **Dr. Nirali Jain:** I think the, the most reassuring thing from the preliminary data that we have is saying that there's no difference in pregnancy rates and no difference in life birth,  **Michelle Oravitz:** Awesome.  **Dr. Nirali Jain:** of whether they had chemotherapy or not. After freezing those eggs and going through fertility preservation.  **Michelle Oravitz:** Amazing.  **Dr. Nirali Jain:** Um, in terms of where your body needs to be, I think the oncologist, we, we wait for their green light. **Dr. Nirali Jain:** We wait for their signal to say, you know, she's safe to carry a pregnancy.  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** And then once we do that, we basically treat you like any other patient. So if you're coming in for a cycle, if you're having periods, then it's reasonable to try a natural cycle protocol, wait for your body to naturally ovulate an egg. **Dr. Nirali Jain:** And instead of obviously hoping that egg will fertilize, we, um, use a corpus luteum. We use the progesterone from the corpus luteum to really support this embryo being implanted into the uterus. Um. Yeah. [00:26:00] And then there's also another side. I mean, some patients don't get their periods back and they always ask like, what if I never get my period back? **Dr. Nirali Jain:** What if I'm just like in menopause because of the chemotherapy agents? And for that, we can start you on a synthetic protocol or basically an estrogen dependent protocol where you take an estrogen pill for a certain number of days. We monitor your lining, then we start progesterone, um, to support your hormones from that perspective instead of relying on your ovaries to release the progesterone that they need, um, and then doing the embryo transfer a few, few days after progesterone starts. **Dr. Nirali Jain:** So there's definitely different protocols depending on where your menstrual health is at after the chemotherapy or after the cancer treatment. Um, but it's important to kind of just know that. That there's options. It doesn't mean that it's the end of the road if you all of a sudden stop getting your period. **Michelle Oravitz:** Yeah, for sure. I mean, 'cause you, technically speaking, you can really control a lot of that. More so for transfers  **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** Retrievals really is kind of like what [00:27:00] eggs you have, what the quality is. But people can be in complete menopause and you guys can still control their cycles for transfer, which is kind of. A huge difference  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** in the  **Dr. Nirali Jain:** exactly. That's exactly right. Yeah. **Michelle Oravitz:** interesting. Any other, um, new, new things that you're, you guys are excited about? I always like to hear about like the new and upcoming things  **Dr. Nirali Jain:** Of course.  **Michelle Oravitz:** actually before, which I thought was fascinating. Yeah.  **Dr. Nirali Jain:** I feel like there's always like updates and, and new data and things like that coming out, but just know, I think it's important for patients to know, like we're constantly, we're, the reason I chose to even pursue this field was because it's new. Right. There's something that we are discovering every day, every year, and that's what makes our, our conferences so important to attend, um, to really just stay up to date. **Dr. Nirali Jain:** Um, but we are, uh, constantly updating our embryology standards, the way we thaw our eggs, and the success rate associated with a thaw and [00:28:00] how we treat our embryos and the media that we use, right? Like, so we're really thinking about the basic science perspective every single day, and that's what makes this field so unique. **Michelle Oravitz:** It is really awesome. And so do you guys specialize specifically on, um. Egg freezing and, and I mean specific fertility preservation in patients that do that have cancer that are going through treatments, do you guys specialize specifically in that? I mean, I know you do range  **Dr. Nirali Jain:** Yeah. Yeah, because it's such a small community, we all have our own niches and we all kind of have our own interests and  **Michelle Oravitz:** Yeah.  **Dr. Nirali Jain:** no like specific training. There are a couple courses that you take that I took in in training as well, just to kind of understand what it sounds like to, I. Council of fertility preservation, patient with and without cancer. **Dr. Nirali Jain:** Um, and then, you know, you kind of just learn by experience and you form a niche for something that you're passionate about. 'cause that's what makes you, you know, really thorough in, in your treatment. [00:29:00] So that's one of my interests. Um, and, but I would say,  **Michelle Oravitz:** training for that. It's just like  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** just know how to treat that in  **Dr. Nirali Jain:** exactly.  **Michelle Oravitz:** especially if you're interested in doing that.  **Dr. Nirali Jain:** Exactly. That's exactly right. It's kind of, it just comes with the experience comes with your mentors and who you're surrounded by, and everyone kind of helps each other get to that point. But there are several specialists in our practice at RMA that specialize specifically in fertility preservation in cancer patients. **Dr. Nirali Jain:** So we have a close communication with our oncologist and they know who to refer to within the practice because everyone has their own little interests.  **Michelle Oravitz:** Amazing.  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Um, definitely. I, like I said, I really enjoy picking your brain because it's a lot of fun for me. I, I do  **Dr. Nirali Jain:** Totally.  **Michelle Oravitz:** acupuncture, so  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** and I, I think that it's just so crazy that our fields don't work together. I mean, we kind of do, but I think, I just feel like it would be so great  **Dr. Nirali Jain:** exactly.[00:30:00]  **Michelle Oravitz:** the expertise because you guys have immense. Benefits like in, in, uh, technology and incredible innovations and, and then the natural aspect of really understanding the, the body. And I, I just think that it would work so amazing together if it was more of like a thing. 'cause it, I know in China they actually combine the two  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** eastern.  **Dr. Nirali Jain:** Yeah, I mean I think that that's so important and there is data that shows, you know, there's actually a recent study that came out just a few weeks ago on the benefits of acupuncture for fertility patients. And we know that, I mean, I recommend it to all of my patients, specifically the day of the embryo transfer. **Dr. Nirali Jain:** We, luckily, we offer it on site at RMA and we have acupuncturists that come in and, and do a session before and after the embryo transfer, and I think. A lot of that is targeted towards stress relief. But I also think that holistically it's important to feel at your best when we're doing something that's so crucial to your, to your health. **Dr. Nirali Jain:** So to really focus on the diet, focus on stress relief, [00:31:00] focus on meditation, yoga, whatever it takes to get to your best wellbeing when you're going through fertility treatments, um, is so important. So I appreciate  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** like you that really specialize in the other side of. Of this, because I do consider it still part of the holistic medicine that we need to really maximize success for our patients. **Michelle Oravitz:** Awesome. Well,  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** Jane, this is such a pleasure Of talking to you. You've given us some, so much great information and we've definitely dived into a, do a topic that I don't typically, I haven't yet spoken about. But, um, that being said, it's such an important topic to talk about. And thank you so much for coming on today. **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** course. **Michelle Oravitz:** I get off, how can people find you?  **Dr. Nirali Jain:** That's a great question. So I have, um, a social media page. I, it's called Expert nc. So like EGG,  **Michelle Oravitz:** I  **Dr. Nirali Jain:** um, expert nc. Try, tried to make it a little bit humorous. Um, but I'm all over social [00:32:00] media and would love to hear from anyone that is listening. I, you know, every, every day I get different, um, dms and I'm happy to respond. **Dr. Nirali Jain:** I love hearing about everyone else's. Stories and things like that. Um, so that is kind of my main, main social media platform. Um, and then through like RMA and Reproductive Medical Associates, we also have a YouTube channel. We have an Instagram page, um, of our office available, um, as well that is public. **Dr. Nirali Jain:** So you can find us pretty easily if you just kind of hit Google. But um, yeah, I'm kind of developing my social media platform as the expert and I hope it grows.  **Michelle Oravitz:** Love it. Great.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** was such a pleasure talking to you. Thank you. so much **Dr. Nirali Jain:** Thank you. **Michelle Oravitz:** today.  **Dr. Nirali Jain:** Of course. Thank you so much for having me.  [00:33:00]   

IVIRMA is so big, they had 1,400 people just at their international congress. But what does it take to implement change, scale care, and keep the patient experience high inside an organization that large?This week's guest, Dr. Thomas Molinaro, Chief Medical Officer of IVIRMA North America, shares what's working, what's still being figured out, and what challenges fertility networks of every size should be preparing for.Tune in to hear about:The AI solution they're using to save REI time (and how it's going so far)What they've learned from piloting patient journey platformsTheir APP-to-REI ratio and how they approach shared workflowsThe evolving debate over who performs ultrasounds (REIs or sonographers?)The marketing on behalf of REIs before the patient walks in that is critical to careIf you're curious about the operational future of large fertility networks—or want a blueprint for scaling thoughtfully—don't miss this episode with Dr. Molinaro.

O tema deste podcast é “A Vila dos Trabalhadores do Vale dos Reis – Deir el-Medina ” com o Prof. Dr. Moacir Elias Santos. O Vale dos Reis é a região onde foram construídas as tumbas dos faraós que governaram o Egito durante o Reino Novo. Ao observar as tumbas faraônicas, nota-se que foram realizadas por uma mão de obra especializada. O Prof. Dr. Moacir Elias Santos conversou conosco sobre a vila de Deir el-Medina, organizada para abrigar os trabalhadores que construíram as tumbas do Vale dos Reis. Quem eram essas pessoas, como estavam organizadas e como era o seu cotidiano foram algumas das questões abordadas nesta entrevista.

Anexos al abecé de la música popular de Brasil en forma de compilaciones. Intervienen: Martinho da Vila, Nelson Cavaquinho, Maria Creuza, Joâo Bosco, Mestre Marçal, Joâo Nogueira, Maria Bethânia, Carmen Miranda, Mário Reis, Orlando Silva, Isaura Garcia, Jacob do Bandolim, Linda Batista, Nelson Gonçalves, Os Originais do Samba y Martinho da Vila.Escuchar audio

Um Bom Dia Para Você! Todos os dias, às 06h30. Lindas mensagens de vida para o seu dia-a-dia, com Padre Dirceu Junior dos Reis.

Um Bom Dia Para Você! Todos os dias, às 06h30. Lindas mensagens de vida para o seu dia-a-dia, com Padre Dirceu Junior dos Reis.

OB/GYNs are entering the IVF space—but what role should they play?This debate is heating up in fertility medicine, and Dr. Stephanie Kuku, a former OB/GYN surgeon in the NHS and now Chief Knowledge Officer at Conceivable Life Sciences, offers her global, tech-forward perspectiveIn this episode, she talks through:What REIs and OB/GYNs really need from each otherWhere the line is on fertility care qualificationsWhat REI oversight could look like in different countriesHow new tech may expand REI roles (not replace them)How Conceivable is building collaborative care models (including their current 100-patient IRB study)The field is changing. How will REIs lead the way forward?

Por Pr. Miquéias Lima. | 2 Reis 5:1-19 | https://bbcst.net/R9269N

Nach den Platin-Podcasts 549 und 658 stand einer DER weltweit erfolgreichsten Sportkletterer, Alex Megos, Jürgen Reis bereits zum dritten Mal Frage und Antwort. Mittlerweile ist der 31-jährige Erlanger nicht mehr „nur“ Kletterprofi, sondern als Mitgesellschafter der „Frankenjura Academy“ auch im Climbing-Business aktiv. Doch welches konkrete und wohl einzigartige Konzept steckt hinter dem „Kompetenzzentrum für den Klettersport in Deutschland“, wie es die Website der Kletter- und Boulderhalle verspricht? Wie resümiert Alex insbesondere das vergangene Jahr und das bereits höchst erfolgreich gestartete 2025? Was für Ziele stehen in den kommenden Monaten an und wie will er – speziell bei Felsprojekten – sein persönliches Anliegen eines möglichst klimaschonenden Kletterlifestyles noch optimaler umsetzen? Last, but not least: Wie und wie umfangreich trainiert der Ausnahmeathlet mit über 30, um idealerweise noch jahrelang seinen Status eines weltweit anerkannten Elitekletterers zu wahren? Alle Antworten erwarten Dich in dieser kurzweilig-faktengeladenen, absoluten High-End-Sendung. Inklusive Power-of-music-Finale via Profimusiker Mark Protze!

Musk by Alyssa Ashley (1969) + Miloš Forman's Hair (1979) + Jacques Levy's Oh! Calcutta! (1972) + Brian DePalma's Hi, Mom! (1970) with Samuel Reis 5/16/25 S7E32 To hear the complete continuing story of The Perfume Nationalist please subscribe on Patreon. 

Quem são os maiores astros do cinema de ação? Hoje julgamos todos eles por sua fama e pelo impacto de seus filmes. Quem será uma lenda?Quem ficará como coadjuvante? Quem você acha que foi injustiçado? Veja também as dicas de lançamentos de séries, livros e filmes, tudo nessa edição de Café Antagonista #63Café Antagonista 2025 é o seu ponto de encontro semanal para ficar bem informado.     Apresentado por José Inácio Pilar, o programa vai ao ar todos os sábados, às 10h e 16h, trazendo uma análise inteligente dos principais acontecimentos do Brasil e do mundo.     Com um jornalismo independente e sem amarras, debate política, economia, notícias  e bastidores exclusivos com um olhar crítico e direto. Inscreva-se no canal para não  perder nenhuma edição do Café Antagonista 2025!                                                                                                                                                          #caféantagonista     Não espere mais, assine agora e garanta 2 anos com 30% OFF - últimos dias.   2 anos de assinatura do combo O Antagonista e Crusoé com um super desconto de 30% adicional* utilizando o voucher 10A-PROMO30 Use o cupom 10A-PROMO30 e assine agora:  café-antagonista (https://bit.ly/promo2anos-cafe)   (*) desconto de 30% aplicado sobre os valores promocionais vigentes do Combo anual | Promoções não cumulativas com outras campanhas vigentes. | **Promoção válida só até o dia 31/05 

Leitura Bíblica Do Dia: João 1:6-13 Plano De Leitura Anual: 2 Reis 24–25; João 5:1-24 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Em 1859, J. A. Norton se declarou imperador dos Estados Unidos. Tendo feito fortuna (e perdido tudo) ele queria ter uma nova identidade e ser o primeiro imperador americano. Quando um jornal publicou o seu “pronunciamento imperial”, os leitores deram gargalhadas. Norton fez pronunciamentos visando corrigir os males da sociedade, imprimiu moeda própria, escreveu à rainha Vitória, propondo-lhe casamento e a união de seus reinos. Vestia-se com uniformes militares reais feitos sob medida. Alguém disse que ele parecia “um rei, cada centímetro”, mas não o era. Não podemos inventar o que somos. Passamos anos tentando descobrir quem somos e questionando sobre o nosso valor. Falhamos, na tentativa de nos definirmos. Somente Deus pode nos dizer quem somos! Ainda bem que Ele nos chama de Seus filhos e filhas quando recebemos a salvação em Seu Filho, Jesus. João escreveu: “Mas, a todos que creram nele e o aceitaram, ele deu o direito de se tornarem filhos de Deus” (JOÃO 1:12). E esta identidade que temos em Cristo é uma dádiva. Somos Seus filhos amados que “não nasceram segundo a ordem natural, nem como resultado da paixão ou da vontade humana, mas nasceram de Deus” (v.13). Deus nos dá nova identidade em Cristo. Podemos parar de nos esforçar e nos compararmos com os outros, porque Ele nos diz quem somos. Por: WINN COLLIER

Außerdem: Aufgewärmter Reis - Warum er gefährlich und gesund sein kann (06:25) // Habt Ihr Feedback, Anregungen oder Fragen, die wir wissenschaftlich einordnen sollen? Dann meldet Euch über Whatsapp oder Signal unter 0162 344 86 48 oder per Mail: quarksdaily@wdr.de. Von Sebastian Sonntag.

Leitura Bíblica Do Dia: Salmo 19:1-6 Plano De Leitura Anual: 2 Reis 22–23; João 4:31-58 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Em 2021, um esforço internacional possibilitou o lançamento do telescópio espacial James Webb para investigar profundamente o Universo, a cerca de 1,5 milhão de quilômetros da Terra. Essa incrível ferramenta de tecnologia astronômica se deslocará pelas profundezas do espaço e examinará as estrelas e outras maravilhas celestes; se tudo funcionar, o James Webb nos proverá com fotos incríveis e muita informação. Mas a sua missão não é nova. Na verdade, o profeta Isaías contemplava as estrelas quando disse: “Olhem para os céus; quem criou as estrelas? Ele as faz sair como um exército, uma após a outra…” (ISAÍAS 40:26). “Noite após noite” elas nos falam do nosso Criador que trouxe este Universo imenso e insondável à existência (SALMO 19:2), com cada um dos incontáveis corpos celestes luminosos que silenciosamente agraciam nosso céu noturno (v.3). Foi o próprio Deus quem decidiu quantas destas luzes existiriam: “Conta as estrelas e chama cada uma pelo nome” (SALMO 147:4). Quando a humanidade envia sondas elaboradas e fascinantes para explorar o espaço, podemos usufruir das maravilhas encantadas que elas captam, porque cada uma delas aponta para Aquele que fez o sistema solar e tudo o que existe além dele. Sim, os céus, as estrelas e tudo que existe “proclamam a glória de Deus” (19:1). Por: DAVE BRANON

 A medicina passou por inúmeras transformações ao longo dos anos – desde avanços tecnológicos até mudanças na relação entre médicos e pacientes. Mas, no centro da profissão, continua um pilar essencial: o cuidado.Neste episódio, Drauzio Varella recebe o dr. Rogério Reis, vice-presidente dos Hospitais Rede Américas, e o dr. Gustavo Fernandes, vice-presidente da Oncologia Américas, para uma conversa sobre os desafios da profissão médica.Vamos explorar a realidade da rotina médica: como é, de fato, o dia a dia de um médico? Quais são os principais desafios da profissão? Quais dilemas e pressões esses profissionais enfrentam? E como as novas tecnologias estão transformando a prática médica e a rotina hospitalar?Assista!Conteúdo produzido em parceria com Rede Américas.Veja também: Qual é o papel da enfermagem?

Leitura Bíblica Do Dia: Salmo 147:1-5 Plano De Leitura Anual: 2 Reis 19–21; João 4:1-30  Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira:  Às vezes, viver com dor e fadiga crônica leva-nos a ficar isolados em casa, solitários. Várias vezes, já me senti ignorada por Deus e pelos outros. Ao orar numa caminhada matinal com meu cão de serviço, eu lutava com esses sentimentos. Percebi um balão voando no céu; as pessoas nele podiam ter uma vista panorâmica do meu bairro, mas não me viam. Enquanto passava pela casa dos vizinhos, pensei e suspirei. Quantas pessoas por detrás daquelas portas se sentiam despercebidas e insignificantes? Então pedi ao Senhor que me desse oportunidades para demonstrar aos meus vizinhos que eles são vistos e têm valor para mim e para Ele. Deus determinou o número exato das estrelas que Ele criou, nomeando-as uma a uma (SALMO 147:4); isso mostra como o Senhor é detalhista. A Sua força (Sua percepção, discernimento e conhecimento) não tem limites no passado, presente ou futuro (v.5) Deus ouve cada lamento desesperado e vê cada lágrima silenciosa com a mesma clareza com que percebe os suspiros de alegria e as fortes gargalhadas. Ele vê quando tropeçamos e quando estamos triunfantes. Ele entende nossos medos mais profundos, nossos pensamentos mais íntimos e nossos sonhos mais selvagens. Sabe de onde viemos e para onde vamos. À medida que Deus nos ajuda a perceber e amar nosso próximo, podemos confiar que Ele nos vê, compreende e se importa conosco.  Por: XOCHITL DIXON 

Autorin Dacia Maraini wurde in den 1940er Jahren mit ihrer Familie in einem Internierungslager in Japan gefangen gehalten. In „Ein halber Löffel Reis“ verarbeitet sie ihre traumatischen Erinnerungen. Sie schreibt über Hunger und die Macht der Poesie. Maraini, Dacia www.deutschlandfunkkultur.de, Lesart

Autorin Dacia Maraini wurde in den 1940er Jahren mit ihrer Familie in einem Internierungslager in Japan gefangen gehalten. In „Ein halber Löffel Reis“ verarbeitet sie ihre traumatischen Erinnerungen. Sie schreibt über Hunger und die Macht der Poesie. Maraini, Dacia www.deutschlandfunkkultur.de, Lesart

What if a single mistake by the European Central Bank could send Europe into a recession? Ricardo Reis, one of the most awarded Portuguese economists of his generation, dismantles the myths around inflation and shows why keeping it under control is a delicate art - with inevitable costs.In this episode of It's Not That Simple, the professor of Economics at the London School of Economics, dismantles the idea that this variable can be easily controlled - especially when political decisions, public expectations, and global shocks intersect.In this conversation, Ricardo Reis reminds that the pandemic and the war in Ukraine were two major tests for monetary policy. In 2020, central banks feared deflation and lowered interest rates. In 2021, people spent more than expected - and inflation surged. When the second shock hit - the war - expectations were already unanchored. «It was this accumulated error that made 2022 inflation more persistent».The response - raising rates - worked. «Inflation fell without unemployment rising, but it would have dropped faster if there had been a recession». That's the dilemma that Reis knows well, because he is also an academic consultant to the Bank of England, the Riksbank and the Federal Reserve Bank of Richmond.And now? The worst is behind us, but expectations have changed. The trust  in the ECB is no longer what it once was.Beyond that, the tariffs imposed by the US on imported goods are the next test, according to the professor. «They'll generate domestic inflation and a recession», but the risk is global, as they trigger trade wars and could force Europe to retaliate. Could the result be a recession in Europe, as well?

Leitura Bíblica Do Dia: Romanos 12:9-18 Plano De Leitura Anual: 2 Reis 17–18; João 3:19-36 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Correr uma maratona significa extenuar-se ao limite, física e mentalmente. Porém, para a estudante Susana, 14, a corrida tem a ver com levar outra pessoa no percurso. Ela sempre leva seu irmão mais velho, Jessé, empurrando a cadeira de rodas dele. Quando Jessé tinha quase dois anos, ele teve uma parada cardíaca que o deixou com uma lesão neurológica grave e paralisia cerebral. Hoje, Susana renuncia os seus próprios objetivos na corrida para que Jessé possa competir com ela. Quanto amor e abnegação! O apóstolo Paulo pensou em amor e sacrifício quando encorajou os seus leitores a amarem-se “com amor fraternal” (ROMANOS 12:10). Ele sabia que os cristãos romanos lutavam com a inveja, ira e fortes desentendimentos (v.18). Por isso, ele os encorajava a permitir que o amor divino fosse a regra no coração de cada um. Este tipo de amor, enraizado no amor de Cristo, sempre lutaria para dar o melhor possível em favor do outro. Seria sincero e levaria a um compartilhamento generoso (v.13). Quem ama dessa forma deseja considerar os outros mais dignos de honra do que eles próprios (v.10,16). Como seguidores de Jesus, continuamos na corrida do amor ao mesmo tempo ajudando outros a finalizá-la. Isso pode ser difícil, porém honra a Jesus. Então, por amor, confiemos que Deus nos fortalece a amar e servir as pessoas. Por: MARVIN WILLIAMS

Send us a textEp 275 Wilson Reis BEFORE the UFC Wilson Reis came to us through a legendary team consisting of Macaco & Godoi; Reis witnessed the split between the two master coaches.  We talk about the highs, the lows and the controversy between Godoi and MacacoSpecial Thank You to Matt Giancarlo for sitting in and lining this up Ep 275 Wilson Reis BEFORE the UFC 0:00 plugs/ promotions 0:42 Lytes out intro 1:14 guest introduction1:42 interview start 2:13 American jiu jitsu vs Brazilian Jiu Jitsu 2:59 making adjustments training in the US6:58 4 toughest American grapplers 9:19 beginnings in Jiu Jitsu 11:27 finding Acadamia de Macaco14:15 fallout between Macaco and Godoi 19:43 Macaco and Godoi black belt ceremony 21:16 choosing to stay with Godoi after split 25:24 experience with Charles Oliveira 27:26 plugs/ promotions 28:32 becoming a world champion at brown belt 29:50 rumor of switching to Gracie Barra 31:11 motivation for moving to the United States 32:53 relationship with Lloyd Irvin34:18 Wilson Reis vs Baba Shigeyasu36:26 Wilson Reis vs Justin Robbins37:58 Wilson Reis vs Bryan Caraway41:44 Elite XC financial issues 43:07 Wilson Reis vs Abel Cullum45:29 training with Eddie Alvarez 46:50 managed by Matt Stansell in Bellator 50:28 experience at Bellator 2 51:27 hanging out with Hector Lombard 53:13 thoughts on Alexis Vila 53:50 switching management to KO Reps 55:10 struggles fighting Brazilian opponents 55:52 training partner Matt Makowski56:45 training partner Jared Weiner57:08 problems with X guard in MMA58:32 Wilson Reis vs Deividas Taurosevicius59:21 Wilson Reis vs Zac George1:00:32 Wilson Reis rematch with Patricio Pitbul1:01:30 cancelled bout with Farkhad Sharipov1:03:15 released from Bellator 1:03:27 Wilson Reis vs Bruno Menzezes in Brazil 1:05:00 coaching on TUF 16 1:06:19 thoughts on Myles Jury 1:08:04 Billy Vaughan1:09:07 Wilson Reis vs Owen Roddy1:10:43 cancelled bout with Hugo Viana1:12:01 Wilson Reis vs Ivan Menjivar 1:16:39 advice to fighters 1:18:59 interview wrap up 1:19:46 outro/ closing thoughts Subscribe to the Lytes Out Podcast:https://www.youtube.com/@MMAHistoryPodcastDiscord:https://discord.gg/s3mV6wyNgvSocials: Facebook -https://www.facebook.com/groups/1027449255187255/?mibextid=oMANbwInstagram - https://www.instagram.com/lytesoutpodcast/iTunes - https://podcasts.apple.com/us/podcast/lytes-out-podcast/id1568575809 Spotify - https://open.spotify.com/show/3q8KsfqrSQSjkdPLkdtNWb Mike - The MMA Detective - @mikedavis632 Cash App - $mikedavis1231Venmo - Mike-Davis-63ZELLE: Cutthroatmma@gmail.com / ph#: 773-491-5052 Follow the #LOP team on Instagram: Chris Lytle - Founder/Owner - @chrislightsoutlytle Mike Davis - MMA Detective - @mikedavis632 Joey Venti - Assistant - @aj_ventitreTyson Green - Producer - @ty.green.weldingAndrew Mendoza - Timestamps - @ambidexstressAndy Campbell - Social Media Manager - @martial_mindset_Josh Campbell - ContributerJohn Perretti - Historical ContributerOutro song: Power - https://tunetank.com/t/2gji/1458-power#MMA #UFC #NHB #LytesOutPodcast #LytesOut #MixedMartialArts #ChrisLytle #MMADetective #MikeDavis #MMAHistory #OldSchoolMMA #FiftyFightClub #MMAPodcast #FightPodcastSupport the show

Leitura Bíblica Do Dia: Tiago 1:19-26 Plano De Leitura Anual: 2 Reis 15–16; João 3:1-18 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Furioso, gritei quando um caminhão cortou a minha frente. Então vi um número de telefone e a mensagem: “Como estou dirigindo?”. Liguei de meu celular e uma mulher me atendeu, perguntando o motivo do contato. Despejei toda a minha frustração, e ela anotou a placa do caminhão. Então, ela disse, com a voz desanimada: “Sabe, o senhor também pode ligar para registrar elogios a um bom motorista”. A voz cansada da atendente imediatamente feriu minha arrogante presunção. Senti-me totalmente constrangido. Em meu zelo por “justiça”, não parei para refletir sobre como meu tom rude poderia afetar aquela mulher no seu trabalho já difícil. A desconexão entre a minha fé e o fruto que produzi foi devastadora. O livro de Tiago aborda sobre a lacuna que há entre nossas ações e nossas convicções. “Entendam isto, meus amados irmãos: estejam todos prontos para ouvir, mas não se apressem em falar nem em se irar. A ira humana não produz a justiça divina” (TIAGO 1:19-20). Depois, o autor complementa: “Não se limitem, porém, a ouvir a palavra; ponham-na em prática” (v.22). Nenhum de nós é perfeito. Às vezes, nossa “direção” na vida precisa de ajustes, que se iniciam pela confissão e pedidos de socorro a Deus, confiando que Ele vai continuar aperfeiçoando os detalhes do nosso caráter. Por: ADAM R. HOLZ

Por Pr. Wander Gomes. | 2 Reis 8:1-5 | https://bbcst.net/R9262N

Por Pra. Raquel Nascimento. | 2 Reis 8:1-6 | https://bbcst.net/R9262M2

Por Pr. Wander Gomes. | 2 Reis 8:1-5 | https://bbcst.net/R9262N

Por Pra. Raquel Nascimento. | 2 Reis 8:1-6 | https://bbcst.net/R9262M2

Leitura Bíblica Do Dia: 1 Tessalonicenses 2:7-12 Plano De Leitura Anual: 2 Reis 13–14; João 2 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Assisti o vídeo viral de uma mamãe urso tentando atravessar uma rua movimentada com seus quatro agitados filhotes. Assisti e, rindo, identifiquei-me com a mamãe urso que, um a um, carregava cada filhote até o outro lado da rua, apenas para vê-los correr de volta para onde estavam. Após muitas tentativas frustradas, a mãe finalmente conseguiu encurralar todos os filhotes, e a família atravessou a estrada em segurança. Criar filhos é um trabalho incansável e é a imagem que Paulo usou para descrever seu cuidado pela igreja de Tessalônica. Em vez de enfatizar a sua autoridade, o apóstolo comparou seu trabalho entre eles com o cuidado de um pai e uma mãe com filhos pequenos (1 TESSALONICENSES 2:7,11). Paulo foi motivado por seu profundo amor àquela igreja (v.8) e, assim, continuamente os encorajava, confortava e aconselhava para que eles vivessem “de modo que Deus[considerasse] digno” (v.12). O ardente chamado para que vivessem em santidade vinha do desejo amoroso de que eles honrassem a Deus em todas as áreas da vida deles. O exemplo de Paulo pode nos ensinar ao exercermos liderança, especialmente quando as responsabilidades nos cansam. Empoderados pelo Espírito de Deus, podemos amar, com gentileza e persistência, os que estão sob os nossos cuidados ao encorajar e guiá-los em direção a Jesus. Por: LISA SAMRA

Leitura Bíblica Do Dia: Gênesis 31:19-21; 32:22-30 Plano De Leitura Anual: 2 Reis 10–12; João 1:29-51 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Uma estatueta de madeira, um deus familiar, fora roubado e sua proprietária reportou o caso à polícia. Pensando terem encontrado o ídolo, os oficiais a chamaram para fazer o reconhecimento, perguntando-lhe: “Este é o seu deus?”. Ela respondeu, tristemente: “Não, meu deus é muito maior e mais bonito do que este”. Há tempos, muitos tentam dar forma ao conceito de divindade, esperando ser protegidos pelo deus que criaram. Talvez tenha ido por isso que Raquel, esposa de Jacó, “roubou os ídolos da casa que pertenciam a seu pai” quando fugiram de Labão (GÊNESIS 31:19). Mas a mão de Deus estava sobre Jacó, apesar da idolatria oculta (v.34). Nessa mesma viagem, Jacó lutou a noite inteira com “um homem” (32:24). Ele percebeu que seu oponente não era um simples ser humano e disse, ao nascer do dia: “Não o deixarei ir enquanto não me abençoar” (v.26). O homem mudou seu nome para Israel (Deus luta) e o abençoou (vv.28-29). Jacó chamou aquele lugar de Peniel (a face de Deus), pois disse: “Vi Deus face a face e, no entanto, minha vida foi poupada” (v.30). Este Deus, único e verdadeiro, é infinitamente maior e mais belo do que qualquer coisa que possamos imaginar. Ele não pode ser esculpido, roubado ou escondido. Porém, como Jacó descobriu, podemos nos aproximar dele! Jesus ensinou os Seus discípulos a chamar este Deus de “Pai nosso que estás no céu…” (MATEUS 6:9). Por: TIM GUSTAFSON

Zen is a practice to deeply explore and fully live our true Self. Might the Koan about the stone deep down in the sea of Ise be a helpful pointer

Leitura Bíblica Do Dia: João 20:11-18 Plano De Leitura Anual: 2 Reis 7–9; João 1:1-28 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Dois irmãos foram adotados por famílias diferentes, mas um teste de DNA possibilitou seu reencontro quase 20 anos depois. Quando Vicente leu a mensagem de Celso, ele pensou: “Quem é esse estranho?”. Celso perguntou o seu nome antes da adoção, e ele disse: “Túlio”. Assim, Celso teve certeza de que aquele era seu irmão. Ele foi reconhecido pelo nome! Veja como um nome é essencial na história da Páscoa. Maria Madalena foi até o túmulo de Cristo e chorou ao perceber que Seu corpo havia sumido. Jesus lhe perguntou: “Mulher, por que está chorando?” (JOÃO 20:15). No entanto, ela não o reconheceu até que Ele dissesse seu nome: “Maria!” (v.16). Ao ser chamada, ela “exclamou: ‘Rabôni!' (que, em aramaico, quer dizer ‘Mestre!')” (v.16). A reação dela expressa a alegria que os seguidores de Jesus sentem na manhã de Páscoa, reconhecendo que nosso Cristo ressurreto venceu a morte por nós e trata a cada um de nós como Seus filhos. Como Ele disse a Maria: “Eu vou subir para meu Pai e Pai de vocês, para meu Deus e Deus de vocês" (v.17). Os dois irmãos reunidos fizeram um pacto de se reaproximarem e aprofundarem seu relacionamento. Na Páscoa, louvamos a Jesus por levar Seu sacrifício ao patamar mais elevado do amor a todos os que Ele reconhece como Seus. Ele vive, por amor a mim e a você! Por: PATRICIA RAYBON

Leitura Bíblica Do Dia: Lucas 1:1-4 Plano De Leitura Anual: 2 Reis 4–6; Lucas 24:36-53  Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira:  Certa igreja estava dividida. “Por qual motivo?”, perguntei, e me responderam: “Se a Terra é plana”. Meses depois, vi uma reportagem sobre um homem armado que invadiu um restaurante para resgatar crianças que estariam sofrendo abusos na sala dos fundos. Sequer havia sala nos fundos do local, e o homem foi preso. Nos dois casos, as pessoas agiram a partir de teorias conspiratórias tiradas da internet. Os cristãos devem ser bons cidadãos (ROMANOS 13:1-7) e, como tais, não espalhar informações falsas. Nos dias de Lucas, muito se dizia sobre Jesus (LUCAS 1:1), e algumas falsidades. Lucas não replicou tudo o que escutava, mas agiu como um jornalista investigativo, conversando com testemunhas oculares (v.2), pesquisando “tudo detalhadamente desde o início” (v.3) e escrevendo seus achados num evangelho repleto de nomes, citações e fatos históricos baseados em informações de primeira mão, não em alegações incertas. Façamos o mesmo! Informação falsa é algo que divide comunidades e ameaça vidas; portanto, verificar os fatos é um ato de amor ao próximo (LUCAS 10:27). Ao nos depararmos com uma história sensacional, verifiquemos as alegações com especialistas qualificados e confiáveis, buscando a verdade (sem espalhar o erro). Isso traz credibilidade ao evangelho. Afinal, adoramos aquele que é cheio de verdade (JOÃO 1:14).  Por: SHERIDAN VOYSEY

Leitura Bíblica Do Dia: Isaías 61:1-3 Plano De Leitura Anual: 2 Reis 1–3; Lucas 24:1-35 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Sempre muito ativo, Carlos caçava, pescava e praticava motocross e skate. Mas ele acidentou-se de moto e ficou paralisado do tronco para baixo. Em pouco tempo, ele ficou depressivo e sem perspectivas de futuro. Um dia, porém, alguns de seus amigos o levaram para caçar novamente. Por um tempo, ele apreciou a beleza ao seu redor e se esqueceu de sua lesão. Essa experiência trouxe-lhe cura interior e inspirou-lhe um novo propósito de vida: proporcionar a mesma experiência para outras pessoas como ele através de uma ONG. Ele diz que seu acidente foi “uma bênção disfarçada […]. Agora eu posso servir à comunidade, algo que sempre quis. Estou feliz”. Ele se realiza em prover um local de cura para as pessoas com deficiências motoras graves e seus cuidadores. O profeta Isaías anunciou a vinda daquele que traria cura para os feridos (ISAÍAS 61). Ele iria “consolar os de coração quebrantado” e “dizer aos que choram” (vv.1-2). Depois que Jesus leu essa profecia na sinagoga de sua cidade natal, disse: “Hoje se cumpriram as Escrituras que vocês acabaram de ouvir” (LUCAS 4:21). Jesus veio para nos salvar e tornar-nos completos. Você precisa de cura interior? Volte-se para Jesus e Ele lhe dará “um manto de louvor em vez de espírito deprimido” (v.3). Por: ANNE CETAS

Boek 2 in de Moedige vrouwen-serie. In 1939 ontvlucht de joodse Maria Berlijn. In 2023 reist haar kleindochter Sandra in haar voetsporen om meer te leren over haar oma's verleden. Uitgegeven door Uitgeverij De Fontein Spreker: Marjolein Algera

Leitura Bíblica Do Dia: Lucas 17:11-19 Plano De Leitura Anual: 1 Reis 21–22; Lucas 23:26-56 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Hansle Parchment estava numa enrascada. Ele pegou o ônibus errado para a sua semifinal nas Olimpíadas de Tóquio e, sem dinheiro para outra passagem, ficou sem esperanças de chegar a tempo ao estádio. Ainda bem que ele encontrou Trijana Stojkovic, que era voluntária nos Jogos. Ela lhe deu dinheiro suficiente para uma corrida de táxi. Parchment chegou a tempo de competir e, alguns dias depois, conquistou o ouro na sua categoria. Depois, ele procurou por Stojkovic e agradeceu-lhe por sua gentileza. Em Lucas 17, lemos sobre um leproso samaritano que voltou para agradecer a Jesus por sua cura (vv.15-16). O Senhor entrou num vilarejo onde encontrou dez leprosos e, atendendo ao que pediram, curou-os pela Sua graça e poder. Todos ficaram felizes com a cura, mas apenas um voltou para expressar gratidão. Ele “ao ver- -se curado, voltou a Jesus, louvando a Deus em alta voz. Lançou-se a seus pés, agradecendo-lhe pelo que havia feito” (vv.15-16). Experimentamos diariamente as bênçãos de Deus de variadas formas. Às vezes, é algo dramático, como ter uma oração atendida quanto a um sofrimento duradouro ou a ajuda oportuna de um estranho. Às vezes, as Suas bênçãos também nos alcançam de maneira comum, como quando temos uma tarefa ao ar livre e o tempo fica bom. Como o leproso samaritano, lembremo-nos de agradecer a Deus por Sua bondade sobre nós. Por: POH FANG CHIA

Leitura Bíblica Do Dia: Êxodo 2:11-15 Plano De Leitura Anual: 1 Reis 19–20; Lucas 23:1-25 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Um homem cometeu um crime chocante e foi condenado à prisão perpétua. Nos anos seguintes, estando preso na solitária, ele começou um processo de cura mental e espiritual, arrependeu-se e foi restaurado por Jesus. Hoje, ele tem alguns momentos de interação com outros detentos. Pela graça de Deus, alguns deles receberam Jesus como Salvador e encontraram o Seu perdão, a partir desse testemunho pessoal. Moisés, reconhecido hoje como um grande homem de fé, também cometeu um crime chocante. Quando “viu um egípcio espancar um hebreu”, ele “olhou para todos os lados e, […] matou o egípcio” (ÊXODO 2:11-12). Apesar do seu pecado, Deus, em Sua graça, não rejeitou o Seu servo imperfeito. Ele escolheu Moisés para libertar Seu povo da opressão (3:10). Em Romanos, lemos: “Mesmo assim, do tempo de Adão até o de Moisés, todos morreram, incluindo os que não desobedeceram a uma ordem explícita de Deus” (5:14). Mas, nos versículos seguintes, Paulo afirma que a “graça de Deus” torna possível que nós, apesar de nossos pecados anteriores, sejamos transformados por Ele (vv.15-16). Podemos pensar que os nossos erros nos impedem de conhecer o perdão de Deus e de sermos usados para Sua honra. Mas, por Sua graça, em Jesus podemos ser transformados e libertos para ajudar outros a serem transformados também. Por: TOM FELTEN

Leitura Bíblica Do Dia: 2 Crônicas 20:1-12 Plano De Leitura Anual: 1 Reis 16–18; Lucas 22:27-71 O devocional de hoje está uma bênção! Marque um amigo aqui nos comentários para ler com você! Quando meu filho precisou de uma cirurgia ortopédica, ficamos muito gratos pelo cirurgião que o operou. O médico, prestes a se aposentar, garantiu-nos de que havia ajudado inúmeras pessoas com o mesmo problema. Mesmo assim, ele orou a Deus antes da cirurgia, pedindo que Deus nos desse um bom resultado. E Ele nos abençoou. Josafá, um líder experiente de Judá, também orou durante uma crise. Três nações haviam se unido contra ele e estavam vindo para guerrear. Apesar de ele ter mais de 20 anos de experiência, o rei decidiu perguntar a Deus o que fazer. Ele orou: “Clamaremos a ti em nossa angústia, e tu nos ouvirás e nos salvarás” (2 CRÔNICAS 20:9). Também pediu orientação: “Não sabemos o que fazer, mas esperamos o socorro que vem de ti" (v.12). A atitude humilde de Josafá diante do desafio abriu seu coração para a ação de Deus, que veio em forma de encorajamento e intervenção divina (vv.15-17,22). Não importa quanta experiência tenhamos em determinada área, orar por ajuda desenvolve em nós uma santa confiança em Deus. A oração nos faz lembrar de que Ele sabe mais do que nós e está no controle de tudo. Ficamos em um lugar de humildade, uma postura que Deus se agrada em responder e nos ajudar, independentemente do que acontecerá. Por: JENNIFER BENSON SCHULDT

Leitura Bíblica Do Dia: 2 Coríntios 4:16–5:5 Plano De Leitura Anual: 1 Reis 14–15; Lucas 22:21-46 Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira

“O homem é um animal que ri”, esta é mais uma das grandes definições que a filosofia criou para caracterizar o ser humano. Mas ao longo de toda a sua história a filosofia pouco se pronunciou sobre o riso, e menos ainda fez rir. Não surpreende, é improvável imaginar que do abismo do questionamento saia uma boa piada. O mistério do riso parece uma questão menor em face de perguntas tão sérias, e são poucos os filósofos que se lembram de rir quando questionam a existência de Deus ou analisam o problema do mal. Afinal, quais foram os filósofos ousados – ou seriam irreverentes? – o bastante para escrever uma apologia do riso? ParticipantesMayra TrindadeRafael LauroRafael TrindadeLinksTexto lidoOutros LinksFicha TécnicaCapa: Felipe FrancoEdição: Pedro JanczurAss. Produção: Bru AlmeidaTexto: Rafael TrindadeGosta do nosso programa?Contribua para que ele continue existindo, seja um assinante!Support the show

Leitura Bíblica Do Dia: João 17:3-12 Plano De Leitura Anual: 1 Reis 12–13; Lucas 22:1-20 Vamos ler o devocional juntos? Separe um tempo especial para Deus hoje e faça sua reflexão diária: “Não tema a morte; tema uma vida não vivida, Winnie”, disse Angus Tuck. É especialmente interessante que essa fala seja de alguém que não morreria. No filme A fonte misteriosa (2002), a família Tuck havia se tornado imortal, e o jovem apaixonado por Winnie, implora que ela busque a imortalidade também, para que ambos vivessem juntos para sempre. Mas o sábio Angus compreendia que viver eternamente, em si, não traria contentamento. Nossa cultura diz que a verdadeira felicidade é ser saudável, jovem e cheio de energia para sempre. Mas nada disso nos concede satisfação. Antes de ir para a cruz, Jesus orou por Seus discípulos e futuros seguidores, dizendo: “E a vida eterna é isto: conhecer a ti, o único Deus verdadeiro, e a Jesus Cristo, a quem enviaste ao mundo” (JOÃO 17:3). A nossa realização como pessoas decorre do relacionamento com Deus por meio da fé em Jesus. Ele é a nossa esperança para o futuro e a alegria para o presente. Jesus orou para que Seus discípulos assumissem o padrão da nova vida: que obedecessem a Deus (v.6), cressem que Jesus fora enviado pelo Pai (v.8) e fossem unidos (v.11). Como seguidores de Cristo, olhamos com expectativa para o futuro em que viveremos eternamente com Ele. Mas, enquanto estamos na Terra, podemos viver a “vida plena, que satisfaz” (10:10) que Jesus prometeu, aqui e agora. Por: KAREN PIMPO

#585 - Salmo 110 - Reis Sacerdotes - A vitória do Cordeiro e dos Santos | JB Carvalho by JB Carvalho

Leitura bíblica do dia: 1 Pedro 3:8-16 Plano De Leitura Anual: 1 Reis 10–11; Lucas 21:20-38 Na última primavera, na véspera do dia em que eu começaria a sulcar o solo do meu quintal, uma forte ventania espalhou as sementes de uma árvore de plátano que temos ali. Quando passamos o arado para descompactar a terra, centenas de sementes de plátano foram plantadas. Em apenas 15 dias, havia uma floresta nascendo no meu gramado! Apesar de estar frustrada com a folhagem fora do lugar, fiquei impressionada com a abundância de nova vida que uma única árvore havia gerado. Para mim, cada árvore em miniatura representava um retrato da novidade de vida em Cristo que eu, apenas uma pessoa, posso compartilhar com os outros. Cada um de nós terá incontáveis oportunidades para explicar “a respeito de [nossa] esperança” (1 PEDRO 3:15) ao longo da vida. Quando sofremos “por fazer o que é certo” (v.14) com a esperança que Jesus dá, isso é visível para as pessoas ao nosso redor e pode chamar a atenção daqueles que ainda não conhecem a Deus pessoalmente. Se estivermos preparados para as suas perguntas, poderemos compartilhar a semente pela qual Deus trará vida nova. Não precisamos compartilhá-la com todos ao mesmo tempo, como numa “ventania espiritual”. Ao invés disso, podemos gentil e respeitosamente plantar uma semente de fé no coração que estiver pronto para recebê-la. Por: KIRSTEN HOLMBERG

Neste episódio de Perguntar Não Ofende, voltamos ao tema do impacto dos smartphones nas escolas e no desenvolvimento das crianças e adolescentes. Partindo de novos dados alarmantes — como o facto de os menores passarem, em média, dois meses por ano em frente a ecrãs — debatemos os efeitos da dependência digital, a queda da socialização presencial e a correlação com problemas como ansiedade, depressão e baixa autoestima. A conversa ganha atualidade com a exibição da série “Adolescência” no Reino Unido e a recente reabertura do debate político em Portugal sobre a proibição de smartphones nas escolas. Os convidados são Matilde Sobral e Mariana Reis, fundadoras da Mirabilis, e Augusto Carreira, referência em pedopsiquiatria. Juntos, discutimos a necessidade urgente de agir e de devolver às crianças tempo real para crescerem, brincarem e partilharem emoções.See omnystudio.com/listener for privacy information.

Leitura Bíblica Do Dia: PROVÉRBIOS 18:1-8 Plano De Leitura Anual: 1 REIS 8–9; LUCAS 21:1-19  Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira:  O jornal declarou que Pipo matou o gato que pertencia à esposa do governador, mas isso não era verdade. A única coisa de que ele pode ter sido culpado foi mastigar o sofá na mansão do governador. Pipo era um cão labrador pertencente ao governador da Pensilvânia, na década de 1920. O cachorro foi de fato enviado à Penitenciária Estadual, onde sua foto foi tirada com um número de identificação de prisioneiro. Quando um repórter de jornal soube disso, inventou a história do gato. Porque sua reportagem apareceu no jornal, muitos creram que Pipo era realmente um matador de gatos. O rei Salomão conhecia bem o poder da desinformação. Ele escreveu: “Calúnias são petiscos saborosos que descem até o íntimo de quem ouve” (PROVÉRBIOS 18:8). Às vezes, nossa natureza humana nos faz querer crer em coisas sobre os outros que não são verdadeiras. Porém, mesmo quando os outros acreditam em mentiras sobre nós, Deus ainda pode nos usar para o bem. Na verdade, o governador tinha enviado Pipo para a prisão para que ele pudesse ser amigo dos encarcerados, e Pipo serviu por muitos anos como cão de terapia. Os propósitos de Deus para a nossa vida ainda permanecem, independentemente do que os outros digam ou pensem. Quando nos caluniarem, lembremo-nos de que a opinião de Deus e o Seu amor por nós é o que mais importa.  Por: JAMES BANKS 

Leitura Bíblica Do Dia: SALMO 145:9-13 Plano De Leitura Anual: 1 REIS 6–7; LUCAS 20:27-47  Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira: Sou muito ansiosa. Cedo de manhã é o pior momento porque estou sozinha com meus pensamentos. Por isso gravei esta citação de Hudson Taylor no espelho do meu banheiro, onde eu posso vê-la quando estou me sentindo vulnerável: “Existe um Deus vivo. Ele fala por meio da Bíblia. Ele é verdadeiro em Suas palavras e fará tudo o que prometeu”. As palavras de Taylor resultam de anos de caminhada com Deus e nos lembram de quem Ele é e tudo o que Ele pode fazer em nossos momentos de enfermidade, pobreza, solidão e tristeza. Taylor não apenas sabia que Deus é fiel, ele vivenciou a Sua fidelidade. E porque ele confiava nas promessas de Deus e o obedecia, milhares de pessoas entregaram a sua vida a Jesus. Confiar em Deus e Seus caminhos ajudou Davi a reconhecer que o Senhor é fiel. Ele escreveu o Salmo 145, uma canção de louvor ao Deus que ele tinha experimentado ser bom, compassivo e fiel a todas as Suas promessas. Quando confiamos e seguimos a Deus, percebemos (ou entendemos melhor) que Ele é quem Ele diz ser e que Ele é fiel à Sua palavra (v.13). E, como Davi, respondemos louvando-o e contando aos outros sobre Ele (vv.10-12). Quando enfrentamos tempos de ansiedade, Deus pode nos ajudar a não vacilar em nossa caminhada com Ele, pois Ele é fiel (HEBREUS 10:23) Por: KAREN HUANG 

What if our skin—our most visible organ—is actually one of the best gateways to longevity and vibrant health?This week's guest is Dr. Carolina Reis Oliveira—a brilliant scientist, a bio-chemist with a focus in stem cells and tissue engineer who's redefining what it means to age well. As co-founder and CEO of OneSkin, Carolina's using cutting-edge biotechnology to not only improve how skin looks—but how it functions at the cellular level.This conversation isn't just about skin. It's about the mindset behind bold innovation. It's about resilience, purpose, self-doubt, and what it takes to move through uncertainty when the stakes are high.As you listen, I invite you to tune into the psychology beneath her success. Ask yourself: What's your relationship with aging? And where in your life might courage and conviction unlock something greater?I think you're going to love this conversation with Dr. Carolina Reis Oliveira.____________________________OneSkin is offering a great discount to the Finding Mastery community. Go to https://www.oneskin.co/findingmastery and use the code FINDINGMASTERY for 15% off your order.____________________________Get Dr. Mike's Morning Mindset Routine here: https://findingmastery.com/morningmindset/Get exclusive discounts from our sponsors here: https://findingmastery.com/sponsors/Watch this episode and many more on our YouTube Channel.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Arkansas pitcher Reis Beuerlein is on the show after throwing a perfect game against Colorado State.

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you've been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that? In this episode, Dave Asprey uncovers the cellular biology of hair thinning with longevity researcher Carolina Reis Oliveira. You'll learn how senescent cells (aka zombie cells) hijack your scalp, disrupt follicle function, and silently accelerate hair loss—and how a breakthrough peptide might stop it cold. Carolina reveals brand-new clinical research on OS-01, a molecule shown to increase hair density by 40% in just 6 months. But this isn't a product pitch—it's a paradigm shift. Together, they explore the hidden drivers of hair aging, from hormone shifts and stress cascades to microbiome imbalances and inflammation, plus the real science behind what can actually regrow hair. What You'll Learn in This Episode: • How “zombie cells” (senescent cells) sabotage your hair from the inside out • The science behind the OS-01 peptide and how it reverses visible hair thinning • Why thinning hair isn't just genetic—and what else is driving it • How stress, hormones, and aging collide to trigger follicle dysfunction • What your scalp microbiome has to do with regrowth and hair density • How to stack red light, peptides, and topicals for real, measurable results ***Visit oneskin.co/DAVE and use code DAVE for and additional 15% off.*** Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OneSkin Instagram – https://www.instagram.com/oneskin.co/ • OneSkin Website: https://www.oneskin.co/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 01:52 — Intro • 02:59 — Is Aging Optional for Your Scalp? • 04:03 — Understanding Scalp and Hair Aging • 05:06 — The Role of Senescent Cells in Hair Loss • 07:25 — Hormonal Influences on Hair Health • 16:10 — Peptide Solutions for Hair Thinning • 18:05 — Clinical Studies and Results • 20:29 — Future of Hair Loss Treatments • 30:16 — Nutritional and Lifestyle Factors • 36:40 — Addressing Senescent Cells and Hair Growth • 37:29 — Minoxidil: Oral vs. Topical Use • 39:32 — Personal Experience with Hair Products • 40:25 — Combining Therapies for Hair Growth • 46:06 — Nutritional Factors in Hair Health • 52:20 — Sun Exposure and Hair Health • 56:40 — Coffee and Hair Growth • 01:00:01 — Launching the New Hair Product See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

José Eduardo Franco dos Reis é filho de brasileiros, e nasceu no município de Águas de Prata, interior paulista. Mas viveu como descendente da nobreza britânica por mais de quatro décadas. Em 1980, quando tinha 22 anos, ele criou o nome fictício de Edward Albert Lancelot Dodd Canterbury Caterham Wickfield e assumiu uma nova identidade – com a qual exerceu a função de juiz. Munido da documentação falsa, ele foi aprovado na Universidade de São Paulo para o curso de direito. Depois, passou em um dos concursos mais disputados do país: a magistratura. De 1995 até 2018, quando se aposentou, José Eduardo assinou mais de 5 mil sentenças como juiz Edward. A fraude só foi descoberta em outubro do ano passado, quando ele tentou tirar uma nova via do RG. Após a denúncia ser aceita, o juiz aposentado virou réu e sua aposentadoria foi suspensa — seu paradeiro é desconhecido desde que ele prestou depoimento. Quem conta essa história é Reynaldo Turollo Jr., repórter do g1 que revelou o caso. Turollo detalha os bastidores da apuração e o que o homem contou à polícia quando foi ouvido. "Ele fala que teve um irmão gêmeo que foi adotado e criado por uma família nobre inglesa”, conta.

Listen in as Bread of Life playwright Frank Pagliario, director Leslie Kincaid Burby, along with the cast of Nikaury Rodriguez, Jesse Castellanos, Miguel K. Reis, Laura Fois, & Cameron Mark Russell, discuss Catholic School upbringing, charismatic cults, Biblical and modern … Continue reading →