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My guest today is Dr. Sabine Hazan: a physician, specialist in gastro-enterology, internal medicine, hepatology and Gut Flora/Microbiome. This episode is all about Healing the body & the world through the Microbiome. Sabine has 20+ years of experience leading 300+ clinical trials for cutting-edge research. Since March 2020, she's been at the forefront of Covid research, leading clinical trials for its treatment. We talked about: 2:00 - Sabine's Covid research through the Microbiome & Bifidobacterium 10:30 - Bifido in severe Covid patients vs. immuned to Covid patients 15:00 - natural immunity to Covid: learning & researching 19:00 - how much Bifidobacterium do we have? 22:20 - censorship in science, the price we pay & building new uncensored alternatives 29:30 - Sabine's healing philosophy 36:00 - the PCR tests lie, lack of doctors' training for Covid treatment, and C19 jabs 45:00 - C19 jabs adverse reactions & the bad pregnancy clinical trials 47:40 - is mRNA affecting Bifidobacterium? 49:20 - ways to increase your natural immunity, probiotics 55:00 - doctor-patient relationship, and trust in doctors 1:02:20 - the autism Microbiome treatment, research on autism-vaccines connection 1:17:00 - Sabine's words of hope I hope you enjoy the show; please share it, and leave a review! Sabine's website | Twitter Efrat's Twitter | Telegram | You're The Voice links | Efrat's links Support Efrat's journalistic work: https://www.buymeacoffee.com/efenigson
One of the most important bacteria you have is called Bifidobacteria. They call it the young bacteria which is extremely important for adults too, although it often diminishes when it doesn't have to. Bifdio helps to activate your immune system and more. Learn how to build it up and keep it strong. Episode link: https://www.culturedfoodlife.com/podcast/episode-239-building-up-the-all-important-bifido-bacteria/ Check out this link: https://www.culturedfoodlife.com/building-up-the-all-important-bifido-bacteria/
Today, I am blessed to have here with me Martha Carlin. She is the founder and CEO of BiotiQuest. This company strives to help people feel better by advocating gut metabolism as the key to regaining health by enabling the body to produce and absorb essential nutrients and detoxify toxins effectively. Martha is a citizen scientist. She began her journey to help her husband with Parkinson's disease. Ultimately, her goal is to end the suffering of people with Parkinson's disease by making a cure. Martha shares her discoveries with her undying passion and helps the science world step forward. In this episode, Martha Carlin speaks about our digestive system and its impact on us. She also discusses why the immune system is the one that kills us, not the pathogen. Martha talks about the right time to eat fruits and talks about the sugar shift biotic formula and its clinical trial results. Tune in as we chat about the Krebs Cycle, how the digestive system works, lipopolysaccharide, the Sugar Shift Formula, and antibiotics. Get your BiotiQuest products at 15% off here. http://www.biotiquest.com use the coupon code ketok15 at checkout. Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E S P ON S O R S Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [04:01] You Are What You Eat: Take Care of Your Digestive System! - We are what we eat. That greatly impacts what's going on in the digestive tract. - Lipopolysaccharide is a cell wall component of gram-negative bacteria. When bacteria break down and die, bits of their cell wall remains, and this LPS can enter your bloodstream and trigger inflammation. - Gram-negative bacteria are potential indicators of Parkinson's and other diseases. - A blood test is the easiest way to know if you have high levels of LPS. - Other than LPS, bacteria produce proteins or peptides, which can cause autoimmune diseases. [14:59] You are Being Killed by Your Immune System Response, Not The Pathogen! - When you get an LPS challenge, you can become LPS tolerant. - It's your immune system response that kills you, not the pathogen itself. - The more and more traffic that builds up slowly with that LPs, the more problems you start to see. - Mitohormesis and LPS can both can reprogram macrophages. [24:11] Do You Love Fruits? Eat In the Right Time and Build Your Metabolism - When the season arrives and fruit ripens, you need to eat some fruit. - In this day and age, fruits are always available, and we might always be tempted to eat them. That is something we want to avoid doing. - The goal is to build that metabolism to introduce fruit. - There's just everything in moderation. [29:52] Sugar Shift Formula: Helping People into Ketosis and Improve Blood Sugar - The sugar shift probiotic formula helps people get into ketosis and improve their blood sugar. - The result of the clinical trial is that the group taking the formula stabilized their HBA1C while the group that did not continue to rise. - There was a marked drop in both 90 Day and 80-day marks in the serum lipopolysaccharide. - In indigenous populations, breastfed babies will carry a specific Bifido and fanta strain, a single colony that trains the immune system. [42:09] How Long Does It Take for the Gut Microbiome to Recover From Taking Antibiotics? - Microbiome NEVER recovers from a macrolide. - You have more problems with the resistance that's left behind than you have with antibiotics. - People don't realize how much antibiotics are in the food supply. - All pre-packaged convenience food contains anti-enzymatic things. AND MUCH MORE! Resources from this episode: ● Get Your BiotiQuest products at 15% off here. http://www.biotiquest.com use the coupon code ketok15 at checkout. ● Martha's Quest: https://www.marthasquest.com/ ● Follow Martha Carlin: ● Twitter: https://twitter.com/mcarlin33 ● Linkedin: https://www.linkedin.com/in/marthacarlin/ ● Come and Join us at Keto Con With Martha: https://www.ketocon.org/ketocon-2023/ use ketokamp at checkout for $50 off. ● Join the Keto Kamp Academy: https://ketokampacademy.com/7-day-trial-a ● Watch Keto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E S P ON S O R S Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. *Some Links Are Affiliates* // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸ tiktok | @thebenazadi https://www.tiktok.com/@thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
In this week's episode of ReInvent Healthcare, we're discussing digestion, and the genetic factors that influence the microbiome. Our guest Steph Jackson is a graduate of our nutritional endocrinology program and is our resident microbiome expert. Steph is an ex yogurt maker, currently called the ‘Gut Whisperer' by her clients. She advocates using probiotic bacteria functionally in consideration of each and every person's unique biochemistry, in order to achieve optimal health. Tune in to learn how intricately our digestive bacteria is connected to food and overall health and the role our genes play with all of these factors. IN THIS EPISODE: [03:00] Is there a higher likelihood of having Celiac or Crohn's, if testing positive to certain genes? [5:15] FUT2 SNP gene that is responsible for our secretion of H antigen into our mucosa. [10:00] The Bifido bacteria are like the grandmother of all the short chain fatty acid producing bacteria in the large intestine. [12:50] RS 110402, and RS 242924 are the RS numbers to search for when testing for gut stress and IBS. If you test positive for these numbers, the stress you feel is more likely to affect your gut, than someone else without these results. [16:00] Stress isn't good in any context, unless it's a healthy stress like going for a run. [18:30] AOC1 gene RS 10156191, RS 2052129, RS 1049742. These are RS numbers to search in regards to histamine. [22:00] Many people have mast cell activation and histamine intolerance, and they're struggling and limiting their diet. There may be another reason why the body is sending out these signals. [30:20] The NLRP3 gene that's been associated with Crohn's, colitis, and even celiac disease. RS 10754558 and RS 10733113. [32:00] With the RS 4353135 T variation, there is an increased prevalence of Crohn's. RS 3806265 C variation, it encodes the making of cryopyrin. KEY TAKEAWAYS: Single nucleotide polymorphisms, and the genetic variations can affect the way certain biochemical pathways work for digestion. Due to genetics, stress may affect some people's gut health more than others. Stress isn't good in any sense, unless it's the healthy kind associated with exercise. GUEST BIO: Steph Jackson, ex-yogurt maker now called the Gut Whisperer by her clients, advocates using probiotic bacteria functionally in consideration of your own biochemistry in order to achieve optimal health. After doing the research to build her non-dairy yogurt company she could not keep quiet about some of the things she discovered and is now using her experience in education and curriculum design to create the Friendly Flora Collective. If you are fascinated by how intricately our digestive bacteria are connected to our food and our overall health you will enjoy our time together today. RESOURCES: reinventhealthcare.com/genes/ www.plantpoweredprobiotics.com https://www.friendlyfloracollective.com/
Apparently there is a “dream team” when it comes to a bacteria profile shared by the leanest, healthiest and longest lived people in the world. Bifido bacteria and Akkermansia muciniphila can help your body use food more efficiently and store less calories. Ever wonder why some people seem to stay lean more easily? There’s a good chance they have more beneficial gut bacteria performing important roles like processing food, stabilizing blood sugar and staving off cravings. In this week’s podcast we’re talking about why a gut reset may be just what you need in your weight loss and health journey. For more information and to access the show notes for this episode, visit my website here: https://www.thechristiannutritionist.com/podcast/100
We know that gut health is trending, it's pretty hot right now, right?! Well, tune in to today's episode as Mase explores SIBO with a bonafide SIBO doctor. Small intestinal bacterial overgrowth, it's a deep dive today, exploring what the heck is this actually?! Mason and Dr Nirala cover the nuanced approach required to treating SIBO, exploring why it may be overdiagnosed and other gut symptoms (constipation, food sensitivities and more). If you've ever traveled to a third world country, got some sort of bug, 'fixed it' and then realised you never truly recovered, then today's episode is for you! (Also, if gut health and immunity are important to you, you are going to love today's episode.) Dive in, here are some of the stuff discussed in today's episode: The nuanced nature of SIBO when compared to irritable bowel syndrome To heal from SIBO, a strategic approach is required, not just a one-size-fits-all What role chronic stress plays in suffering from SIBO How hypothyroidism, mould exposure and other autoimmune diseases are connected to SIBO The misunderstanding around 'reseeding' the gut How the 'breath' test works in diagnosing SIBO Which foods to avoid during SIBO Dr Nirala's dietary treatment plan Dr Nirala covers the three possible treatment plans (herbs, antibiotics, diet) A brief touch on the Blood Type diets Who is Nirala Jacobi? Dr. Nirala Jacobi, BHSc, ND (USA) graduated from Bastyr University in 1998 with a doctorate in naturopathic medicine. Dr Nirala practiced as a primary care physician in Montana for 7 years before arriving in Australia and is considered one of Australia’s leading experts in the treatment of small intestine bacterial overgrowth (SIBO), a common cause of IBS. Dr Nirala is the medical director for SIBOtest, an online testing service for practitioners. Dr Nirala is so passionate about educating practitioners that she founded “The SIBO Doctor”, an online professional education platform. Dr Nirala lectures nationally and internationally about the assessment and treatment of SIBO and is the host of the popular podcast The SIBO Doctor podcast for practitioners. Dr Nirala is the medical director and senior naturopathic physician at The Biome Clinic, center for functional digestive disorders in Mullumbimby, New South Wales. Dr Nirala is the co-founder of the Australian Naturopathic Summit. When she is not actively researching, seeing patients or lecturing, Dr Nirala can be found enjoying the beauty of nature Resources: Dr Nirala's Instagram The Human Microbiome Project Dr Nirala's FREE SIBO Questionnaire The SIBO Success Plan 8 Hour Course SIBO Mastery Program (for practitioners) Visceral Manipulation Barral Institute Feeding Your Microbiome (Dr Nirala Podcast with Dr B) The Blue Zones book Healthy to 100 book Blood Type Diet Q: How Can I Support The SuperFeast Podcast? A: Tell all your friends and family and share online! We’d also love it if you could subscribe and review this podcast on iTunes. Or check us out on Stitcher, CastBox, iHeart RADIO:)! Plus we're on Spotify! Check Out The Transcript Here: Mason: (00:00) Hi, Nirala. Nirala Jacobi: (00:02) Hi, Mason. Mason: (00:03) Did I pronounce your name correctly? Nirala Jacobi: (00:04) You did. Mason: (00:06) Okay. Nirala Jacobi? Nirala Jacobi: (00:07) Very good. Mason: (00:08) Yeah, yay. Nirala Jacobi: (00:12) Yes. Mason: (00:13) Okay. Guys, got to do it in person today, which is- Nirala Jacobi: (00:17) What were the chances of that? Mason: (00:19) Considering you live in Wilson's Creek, I think they're pretty good. But in terms of the chances of doing it, two people, that's a party but I think that's a legal party at these times, isn't it? Nirala Jacobi: (00:29) These days, it is. Mason: (00:31) Oh, pretty legal. Goji is sitting in the room if you hear Goj wrestling around, but dogs don't count. Guys, we're talking about SIBO. We got the SIBO Doctor here. I'm following you on Instagram for, I think, like three years. Nirala Jacobi: (00:51) Wow. Okay. Mason: (00:51) Yeah. I've been aware of your work. SIBO has been one of those things I used to say, facetiously, that it got trendy about three years ago in terms of I don't know where you see the mass awareness come about in the naturopathic and medical circles or whether it's even really accepted in the medical circles but, obviously, you would have watched the trend occur and then the mass misdiagnosis and then realisation that we're actually able to test and find out that it is this SIBO, which we'll find out from you what it is. Why did it, all of a sudden, hit mass consciousness? What I see a few years ago anyway. Nirala Jacobi: (01:42) I'm going to go back nine years. I've been a naturopathic doctor for about 22 years now. I have practised in Montana and saw everything from heart disease to urinary tract infections to actual IBS or irritable bowel syndrome. We had really good result rates, but there was always a subset of patients that just did not improve. Then fast forward nine years ago, I sat in a lecture at one of our conferences and heard about SIBO. It was like a light bulb went on because it explained those cases that just didn't improve with conventional naturopathic approaches even to irritable bowel syndrome. Nirala Jacobi: (02:27) Then, I started to become an expert in SIBO. I moved here about 15 years ago, Australia, but I became an expert and started lecturing for other supplement companies and to practitioners and started a breath testing company because there was just nothing here at all about SIBO. I think one of the reasons why it has really exponentially grown the interest is if you think that about 11% of the world's industrialised nation has IBS. IBS, according to conventional medical texts and the conventional medical approach, has no real cure. Nirala Jacobi: (03:18) To find something that actually is the cause of IBS that is so profoundly responsive to treatment, I think, really gave hope to a lot of people. Now, of course, with that comes the fact that SIBO is often, as you mentioned, I do think there is an element of overdiagnosis. Everybody just basically treats according to the symptoms, which is not what I recommend at all. Because in that case, you can use antimicrobials and things like that for far too long. Nirala Jacobi: (03:53) I think it has to do with the fact that there really wasn't other options for people. They really improved when they began to treat SIBO, or I saw a dramatic improvement in my patients when we finally treated the cause rather than just giving probiotics and giving fibre and giving all of the stuff that we know how to do, and people were actually getting worse, not better with those approaches. That was really my journey into this. Mason: (04:22) That was probably about a time when I think naturopathic medicine got a little bit more integrated even. There were all these different pockets. All of a sudden, naturopaths, even though they were specialising in particular areas, became aware of just all these different specialisations, became I did say trendy for that reason, because it was about the end of that era where people were really trusting health coaches who would read up about the symptoms of SIBO and, therefore, put their clients onto an antimicrobial or whatever it was and just flying blind. You've got the breath test of your business where I see it's like if you're in Chinese medicine, you are doing pulse and tongue and the questions diagnosis. If you're in naturopathic medicine, you need that testing most of the time, I'd imagine. Nirala Jacobi: (05:25) Yeah. I'm a gastrointestinal specialist. I don't just do SIBO. I specialise in functional gastrointestinal disorders, so I do a number of tests. This, I think, is a big shortcoming of practitioners where they consider the finances of ordering a test for a patient. I always tell practitioners that I teach, "You're not their accountant. You don't know if they want to test or not want to test, but it's your job to give them the best options and the diagnosis," because if you're just reading, you're not going to get better because SIBO is a really distinct condition that requires a really strategic approach. There's different kinds of SIBO. Mason: (06:10) That's always what happens. Yeah. It's the same with PCOS or whatever it is. There's different arms. Obviously, there's different sources. There's mainly four major causes, is that right? Nirala Jacobi: (06:25) There's four major groups of causes. Mason: (06:27) Okay, okay. Nirala Jacobi: (06:29) But maybe what we should do is backtrack and really define what SIBO is, right? Mason: (06:33) Yeah, good idea. Well leading, you can tell you have a podcast. Nirala Jacobi: (06:35) Yeah. All right. Let's talk about ... so that people can really understand that it's not just bacterial overgrowth, and as soon as you kill the bacteria, boom, that's it, you're cured. In some instances, that's the case, but it's actually the exception rather than the norm. But SIBO stands for small intestinal bacterial overgrowth. It's a condition where bacteria that are typically usually found in the large intestine are, for some reason, found in the small intestine. Nirala Jacobi: (07:03) Now, the surface area of your small intestine is about the surface area of a double tennis court. Imagine having a massive bacterial overgrowth right where you absorb your nutrients, where you release your enzymes, where you do all of these different important digestive functions and, all of a sudden, that surface area is just chock-a-block with bacteria. These bacteria ferment the food that you're eating into hydrogen gas. There's a group of bacteria or a phylum called proteobacteria. The main gram-negative bacteria in that group are Klebsiella, Proteus, E. coli, those types of bacteria that are the biggest culprit for causing SIBO. Nirala Jacobi: (07:47) Why is this happening? This is how we get into the underlying causes. I think one of the main driving cause of SIBO is, imagine you've gone to Bali, you had a case of food poisoning, or if your listener is in America, you've gone somewhere else and you had food poisoning. You came home, it resolved, but then you still have ongoing digestive symptoms. Actually, over time, they become worse, you go to the doctor, they diagnose you with IBS. That is the classic scenario. Nirala Jacobi: (08:19) What happens there is the bacteria that caused the food poisoning are not the bacteria that are causing SIBO, but they're the bacteria that are damaging to the enteric nervous system, which is really the motility, the brain of your gut. You are meant to have this innate ability to clear bacteria from the upper gut, because the body doesn't want them there. You're supposed to sweep them all towards the small intestine. When you've had a case of food poisoning that results in this damage, you actually cannot effectively clear these bacteria from your upper gut. Mason: (08:55) What is it that's affected in the small intestine and it stops you from having the motility to move it out? Nirala Jacobi: (09:03) This part of the nervous system is called the migrating motor complex. It's a part of the enteric nervous system. Enteric just means digestive or your gut. It's basically the brain in the gut. This particular section of the small intestine is meant to clear these bacteria out every 90 minutes on an empty stomach. Imagine that you've had this food poisoning and it damaged that section or that particular part of what clears the gut out in the upper gut. Nirala Jacobi: (09:32) That actually can be tested with a blood test. We're trying to get it to Australia. Because of COVID, we've had some issues. But we do want to offer this test for people to test for these antibodies, because if you know that's the cause, the proper treatment for SIBO for you would be to have antimicrobials, whether that's the conventional antibiotics that are indicated for this or herbs. Then you must follow it up with something called a prokinetic, which is a medicine that aims to reset this migrating motor complex. That's probably the biggest group of people that have this as an underlying cause. Nirala Jacobi: (10:10) But then you also have people that just were totally stressed out for a long time. Chronic stress, as you probably have discussed this before, causes you to be in this chronic fight or flight. If you're in chronic fight or flight, you're not in rest and digest, it turns off your digestion. These natural antibiotic fluids, like hydrochloric acid, bile, digestive enzymes that are meant to kill bacteria are very poorly produced and, therefore, you suffer not just from maldigestion, but then also bacterial overgrowth. That's a different kind of cause of SIBO that then wouldn't necessarily require the prokinetics. Mason: (10:50) Like a stealthy, slow-grown... Nirala Jacobi: (10:54) Yeah, yeah. Mason: (10:54) I like that you're just actually bringing up those antibacterial fluids. I was going to ask you, and you did it straight away. Nirala Jacobi: (11:04) Yeah. Then the other one, there's more, the fourth group ... The first one would be a matter of a problem with motility. That is not just this, what we call, post-infectious IBS. It can also be hypothyroidism, other autoimmune diseases, mould exposure. All kinds of things can cause this problem with motility. Then you have these digestive factors, and not a big one because a lot of people don't think about this, but previous abdominal surgery that causes scar tissue known as adhesions that actually attach to the small intestine in the abdominal cavity and cause like a kink in the garden hose. That prevents bacteria from leaving the small intestine. Also for that, you would need prokinetics. You can see how it's so much more intricate than just, "Here are some antibiotics," or "Here's berberine and here's Allimax." Nirala Jacobi: (11:59) One last thing I'll say about SIBO before the next question is that there are two groups. I've mentioned the proteobacteria that produce hydrogen. There's another group of ancient organisms. They probably live on Mars, too. Honestly, they're like extremophiles. They live on the bottom of the ocean. There are these ancient archaea. They're not even bacteria. They produce methane. Methane, we know, causes constipation. If you're somebody that's been diagnosed with SIBO methane or SIBO-C or SIBO constipation, it's likely that your methane is high. That's a different kind of treatment. That's starting to be thought of as actually a separate condition. That's advanced SIBO discussion. Mason: (12:46) I like that. We always got this travelling of these bacteria up through the ... Is it the ileocecal valve? Nirala Jacobi: (12:55) Ileocecal valve. Mason: (12:57) Ileocecal valve. Is that a constant occurrence of reality? Nirala Jacobi: (13:00) No. Mason: (13:00) No? Nirala Jacobi: (13:01) No, that is not how it happens. These bacteria, they are normal in very, very small amounts. Nothing in your body is really sterile. Nothing really, even though we think it is, but it's not really. Mason: (13:17) But we've been told it is. Nirala Jacobi: (13:17) Yes, exactly. Mason: (13:17) Programmed. Nirala Jacobi: (13:18) Yeah. It's like modern medicine at the time thought that's what it was, but it turns out that one of the most famous bacteria that survives the stomach is H. pylori. We know it can survive very well there. But you have maybe 1,000 bacteria or colony-forming unit per mil in the upper gut, just below the stomach, the duodenum. Then as you progress towards the large intestine, actually, the diversity and the sheer number of bacteria increases. That's normal. Nirala Jacobi: (14:00) These bacteria, even though gram-negatives that cause SIBO, are actually not pathogens. They're called pathobionts. Pathobionts are organisms that you normally find in low amounts. But when they get overgrown, they become pathogenic. I often tell people, my patients, I say, "Your gut is like a white supremacists neighbourhood. It's just one kind of bacteria, and you need diversity and you need low numbers of those organisms." That's what we're aiming for. Mason: (14:36) There's, I guess, an as above, so below, we've sterilised everything in our environment, in our house, and we have low bacterial biodiversity there, we're going to see low bacterial biodiversity internally. Is there a particular macro or even micronutrient cycles that that gram-negative bacteria ... What did you say? What was the group? Nirala Jacobi: (15:02) The group is called proteobacteria. Mason: (15:03) Proteobacteria. Is there anything that would feed them excessively? Nirala Jacobi: (15:08) No, it's basically food. Those bacteria are usually found in higher amounts in the large intestine. They're normal there. A pathobiont becomes problematic when it outgrows its environment or the other bacteria in that location. They've actually just did a microbiome assessment study on the small intestine. I think the other reason, just to briefly sidetrack to get back to your first question, why is this such a big deal now, is because we know so much more. Nirala Jacobi: (15:44) The Human Microbiome Project that's undergoing, it's like discovering the universe, because what happened before we were able to actually understand what was happening in the small intestine, we couldn't culture out these organisms because they would die. They were anaerobes. They couldn't be cultured out. Now that we have this different technology that uses RNA and DNA, we can understand far more. Now we actually understand the normal microbiome of the small intestine a lot more. It's totally fascinating to be in this field of microbiome research. Mason: (16:26) Of the large intestine bacterial testing and analysis of the biome, testing has got a little bit more efficacy with that, is that right? Nirala Jacobi: (16:33) Oh, way more. Mason: (16:34) Way more? Nirala Jacobi: (16:36) Way more, because it used to be culture-based, it turns out it's like fairy dust of what actually is in the large intestine as a representation of the ... We know about Lactobacillus and Bifidobacterium. That is literally just 2% to 5% of your entire microbiome. There are so many more species that do fascinating things. Mason: (16:59) We've had the chat on the podcast a couple of times of why just throwing a probiotic in the gut is ... Quite often, you can get a little bit more sophisticated. Nirala Jacobi: (17:09) I think we're at that place now where ... I'm somebody who used to just do a probiotic. "Yeah, just a couple of Bifido, couple of Lacto, you're good." But now, I'm way more strain-specific. I would use Bifidobacterium lactis HN019 if you're constipated. I'm not going to necessarily give a whole combination of products, or I give you Lactobacillus rhamnosus if you have leaky gut and eczema, for example. It's a lot more fun now than it used to be. Mason: (17:46) Yeah, I can imagine. It's like rather than just having your shotgun, you got the Men in Black chamber. You walk and there's all different types of guns and grenades all over the wall, but in a more life-giving kind of ... Like a seed gun. Nirala Jacobi: (18:01) I like that. Actually, this brings up a really important point, is that even when I went to naturopathic medical school, it was taught to us that we could reseed the gut. Remember that? Mason: (18:15) Mm-hmm (affirmative). Nirala Jacobi: (18:15) We cannot do that. These Lactobacillus and Bifidobacterium, they are response modifiers. They actually do something that is not involving reseeding. If you've lost a lot of your native species because you were on chronic antibiotics for acne, or Lyme disease, or whatever that may be, if you've lost a lot of your species or have really reduced them, probiotics will not reseed what you've lost. You can't do that. It's a really important point because some practitioners still preach this method, but I had to really switch my thinking. I tell my patients, "I'm going to give you this probiotic for this symptom. I'm not going to give it to you because you're reseeding." You can't do that. Not if it's 5% or 2% of the gut. Mason: (19:01) In terms of it being for the symptoms specifically, is that because the probiotic is able to do it like having a short-term effect within the gut and then it's on its way? Nirala Jacobi: (19:11) Yes, exactly. Exactly. That's what probiotic research is really good at, is seeing what symptoms a particular strain can alleviate. Mason: (19:24) Obviously, we've touched that medication and antibiotics can be another reason why we could lead to SIBO and IBS. Nirala Jacobi: (19:33) Medications like proton pump inhibitors that stop stomach acid, there's some debate whether or not, but I have seen people definitely have a problem with SIBO after using chronically proton pump inhibitors, and others that are more slowing the gut down. Medications like opiates and things like that, morphine will really slow it down. But then that's pretty temporary, you're not going to see chronic SIBO with that. Mason: (20:05) Yeah. The stress factor, you're looking at a combination, mould exposure, stress, and antibiotic here and there, it's kind of a cocktail of reasons, I imagine. Nirala Jacobi: (20:18) This is always the overwhelming part for people. It's like, "Oh, my God, where do I even begin?" But this is where a really skilled practitioner can ... I actually have a questionnaire that you can get on thesibodoctor.com. That is a questionnaire about finding the cause for SIBO. You can download it, it's free, as is the diet that I've devised for SIBO. You can take that to your practitioner and it can whittle it down to what the possible causes are. It goes through these four groups of causes. Mason: (20:52) That's cool. Something that I really like about your approach is I'm hearing just on your website right here, you've got the patient course, practitioner course. Obviously, you're a practitioner and you've got a focus on the patient being able to understand it and get to the source themselves, getting, for lack of a better word, empowered around it, getting informed, and then bridging the way that they can then take that questionnaire and they can create a dialogue between them and their practitioner. Mason: (21:25) It's something we always ... You go there automatically. It's why I like your work. It's something we always try to do and talk about on the podcast when we're chatting with practitioners as well, because it diffuses it. You've even got great resources there of like once you've treated yourself, how are you going to stay out of that practitioner office, which it's overlooked quite heavily. I don't know what your thoughts are on that. Nirala Jacobi: (21:49) The SIBO Success Plan, which is the patient course, it's an eight-hour course that goes through everything from leaky gut to all these different things, it really was born out of a necessity. In a perfect world, everybody would have a practitioner that is SIBO savvy that can nail this thing for you. But I got calls from people or emails from people in Finland and from all over the world that just said, "There's no one here. No one can help me." This is the course that really had to be made for people like that. They don't have a practitioner. Mason: (22:26) You go straight to sibodoctor.com/sibo-success-plan/. So good. Eight hours? Nirala Jacobi: (22:35) It's eight hours because it's eight modules. One of the reasons I shouldn't say I love SIBO, because SIBO is a medical condition, but if a practitioner is listening to this, if you can master SIBO, you got the gut down. You understand practically most of the things that can go wrong with the gut, bearing in mind that there are other issues that are more anatomical problems and stuff. Nirala Jacobi: (23:06) But everything from, like I mentioned, leaky gut, the effects of stress on the gut, what to do when you're constipated, how to help yourself with different home treatments, I have an online dispensary guide that guides you through all the major products that are out there that are for SIBO, and pros and cons and stuff like that, and food sensitivities, histamine intolerance, salicylates, oxalates, SIFO. SIFO is small intestine fungal overgrowth, which often accompanies SIBO. There's a lot there that I had to cover to really make it comprehensive for people. Mason: (23:46) Do you do a leaky gut analysis on a patient as well? Is there always going to be a presence of SIBO and therefore- Nirala Jacobi: (23:55) Not always. No. Mason: (23:57) No? Nirala Jacobi: (23:57) The thing is SIBO can cause leaky gut. Mason: (24:00) Can cause... Right. Nirala Jacobi: (24:00) But just because you have leaky gut doesn't mean you have SIBO. But it is a major cause of it. They've even done research on, all right, well, one month after clearing SIBO, the intestinal permeability was also resolved. If you have the wherewithal and the fortitude to get rid of SIBO, then you can also get rid of leaky gut. Mason: (24:24) I think it's important that you said you do love SIBO because it's, as I mentioned before in the podcast, we're at that point where my mum, she's nine years post-aneurysm, 24-hour care, in a wheelchair all the time. We've done well to keep her off medications and keep her going well, but it's just this bloating that's been there and it finally got to the point where we're like, "Right, we got to test for SIBO," and so we've got there. We're doing the breath test thing. Is it five days? Nirala Jacobi: (24:52) No, it depends on if you're constipated. Mason: (24:55) All right. Nirala Jacobi: (24:55) If you're constipated, it's a 48-hour prep for this test because what we want to do is have bacterial fermentation really down, really reduced before you then start the test, which is a three-hour test where, first, you get up in the morning, you drink this very sugary drink. That's a prebiotic substance that promotes the growth of those bacteria that you've starved over the past two days, one or two days. Then you're measuring your breath every 20 minutes. If we see a rise of hydrogen or methane before 90 minutes, that's the window of SIBO. Mason: (25:36) Yeah. If you get the methane, then we're going into that real nerdy, new sector of SIBO. Is that right? Nirala Jacobi: (25:46) Yeah. [Laughing]. Mason: (25:47) For that instance, my stepdad, he's managing that and he's just looking at like, "All right, test, okay, we can handle it," and trying to get a bunch of carers to all unite and align on that and then looking at having the management of the diet. I think the SIBO diet is the thing. That's why I say I appreciate you saying that you love SIBO because ... But I am curious when you're approaching, how do you keep the excitement up with your patients when you're- Nirala Jacobi: (26:21) That's a really good question. I think that even just this morning, I spoke with somebody who has been ill for so long, and I'm not saying that just curing her SIBO is going to be the be-all, end-all. People are complicated. There's no one approach to it. You can have somebody who has childhood trauma. We know from studies that even childhood trauma can cause what they call adverse childhood events. It can cause a major shift in the microbiome, for example. Nirala Jacobi: (26:53) You can have somebody like that that you work with in finding a good practitioner around trauma and regulating their own nervous system. Then you have somebody who just discovered that their house was full of mould, or you have somebody who has an autoimmune disorder or chronic viral infection. It always is different presentations. It forced me to really become really good at all these different conditions, and that's why I think if you can really not just look at SIBO, but the underlying causes for me is where it's really at where I continue to learn also. Mason: (27:32) Yeah. I guess that's the exciting part, is knowing that you're not just going to have another random go at figuring out what's wrong with you, but you're actually ticking things off to be like, "Look, if it's not this, great. We know it's not this. We know it's not this. We know it's not moulds. That means you're getting closer." I think just the trouble is finding a good practitioner. Nirala Jacobi: (27:56) We have an answer for that. On thesibodoctor.com, we have also the SIBO Mastery Program for practitioners. After they've completed all three levels, they're eligible to be listed free as a SIBO doctor approved practitioner, so all the people that are listed in there. We had to purge a whole bunch. We had to start fresh from scratch this January. As we go along, this list will get bigger and bigger, but they all have taken these very extensive training courses that covers all of these topics. I think you're pretty safe. A lot of them do Zoom calls. I will say that. Nowadays, we're forced to do more and more virtually. Mason: (28:37) Which is amazing. Nirala Jacobi: (28:39) It's amazing. It has its drawbacks. I do, as a practitioner, a hands-on practitioner that does physical assessment and certain manoeuvres, I miss that part but- Mason: (28:50) Can you explain what the physical assessment and manoeuvres are? Nirala Jacobi: (28:54) In America, we're trained like physicians. We're actually like naturopathic GPs, if you will. We're trained in physical exams. I always enjoyed that part of my practise, too. Some people have things like the ileocecal valve problem, which is the valve between the small and the large intestine and it can be stuck open, and then you have this backflow problem with bacteria. You can easily manipulate that with using different manoeuvres, or the hiatal hernia manoeuvre, which is part of the stomach moving into the thorax. It's those kinds of things, as well as physical exam and stuff like that. You get a lot of information from looking at somebody's body, for sure. Mason: (29:39) Yeah, 100%. I can get the drawback, if we can get back to getting in-person as much as possible, great. Otherwise, if you're in Finland and you don't have a practitioner, "Oh, well, that's wonderful." Nirala Jacobi: (29:49) Honestly, well, 90% of my practise is virtual, and then sometimes I'm like, "Okay, stand up, lift your shirt, press there." That will have the work. Mason: (29:58) Yeah, you do what you have to do. Nirala Jacobi: (29:59) Yeah. Mason: (29:59) Do you ever recommend for people to be physically manipulating their own gut with massage as treatment? Nirala Jacobi: (30:07) That's a great question because let's hypothetically say ... Well, let me rephrase it. Yes, if it's for just the ileocecal valve. I do have a little video on my Facebook page, The SIBO Doctor, where I go through how to do it, how to actually release the ileocecal valve yourself. It's not going to be as great as when a trained practitioner does it, but it's good. The massaging of the gut, let's hypothetically say that you're a patient that's listening to this and you're like, "Oh yeah, I may have SIBO." Nirala Jacobi: (30:45) You may have had abdominal surgery for things like you may have had caesarian or you may have had your appendix out or you may have your gallbladder out or the myriad of other things that would be considered routine surgeries, and you have adhesions. That is not a good thing to massage your own belly because it can trigger more scar tissue formation, but light touch, we're just talking light touch. For that scenario, I usually refer to a visceral manipulation practitioner. Mason: (31:17) What's that? Nirala Jacobi: (31:19) Visceral manipulation, so the viscera are the organ up in the abdomen. It's extremely light touch but they are trained to actually feel the rhythms of these organs. Don't ask me what that is. Mason: (31:31) Actually, Tahnee, my fiancée, she's a Chi Nei Tsang practitioner. Do you know that? It's Daoist abdominal massage. Nirala Jacobi: (31:37) Oh, okay. Yeah. Mason: (31:38) We've talked a little bit about it. I was wondering whether that's what you were talking about. Nirala Jacobi: (31:41) Right. No. Visceral manipulation, as far as I know, there's a group from The Barral Institute and they have a very specific technique to very gently break down scar tissue or break up scar tissue. Mason: (31:58) Okay. That's good to get that resource because there's people listening to the podcast, like Tahnee's not practising and she gets asked a lot about doing abdominal massage, so to be able to tune in with another group of practitioners that are doing this I think will help a lot of people. All right. Well, that's going to be in the show notes, gang. When we do get to treatment and, obviously, the dietary charts, there's different phases of healing of SIBO? Nirala Jacobi: (32:27) No, so what happened is, okay, so in a nutshell, the food that promotes or that feeds the bacteria are foods that are high in fibre. That makes sense. Those are healthy foods that feed our own microbiome. That's why we want to eat them. In a case of SIBO, the bacteria are like miles further up so they're fermenting in the wrong place, and so you want to minimise those foods. Those foods are known as from FODMAPs, so Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols. Did I miss it all? Did we miss one? Anyways, so these are fermentable fibres. Mason: (33:06) Forgot the A? Nirala Jacobi: (33:09) And. Mason: (33:09) Oh, okay. Nirala Jacobi: (33:13) I know, right? Those are the foods that typically are to be avoided when you suffer from SIBO. What I did is I took that diet from Monash. Fantastic work that they did over there to really pinpoint this. Before then, we didn't really know. I took that and put my own spin on it because I found even with that, people were reacting. I made it more restrictive, also added in SCD stuff and that type of thing, because I'm a very structured person and I don't like wishy-washy, vague treatment plans, and so I needed to structure it for myself. Nirala Jacobi: (33:49) What I found is that I got very good results by having a diet that was in two phases. Then I called it the bi-phasic diet. Phase one was the most restrictive part where you have almost no grains and no fruit and really the high-fermenting foods, and you are basically getting tested for SIBO and you're waiting for your test result. I was already seeing dramatic improvement by the time they came back and yes, indeed, the test says it's SIBO, so then we initiated antimicrobials. That then prevented a massive die-off reaction of just throwing in antimicrobials in a system that was still really activated. Mason: (34:33) Okay. You've got them going for, what, a couple of weeks now? Nirala Jacobi: (34:35) A couple weeks, yeah. Yeah. I really did it for practitioners so that they could also tailor it. It still has different food ... Some people are very sensitive to histamines when they have SIBO, and that means no fermented foods, so no sauerkraut, those kinds of- Mason: (34:55) That was very confusing for people, I think, about 10 years ago when capers and sauerkraut and body ecology diet and all that were going off real big time, and then some people will just get these intense levels of bloating every time they'd eat sauerkraut and kimchis and they wouldn't get it. They're like, "What's going on? This is a healthy food." Nirala Jacobi: (35:14) "Persist. Persist. Keep it up. It's just your body detoxing." No, it's your body reacting. Mason: (35:18) Yeah. Herxing became the ultimate. Just, "Oh, it's just a Herx." Nirala Jacobi: (35:20) Yeah, yeah. Exactly. Mason: (35:24) Is that normally enough to reduce the die-off from being too hard for someone just recently getting on the diet for a couple of weeks? Nirala Jacobi: (35:32) It depends. The other thing is if somebody's really constipated, I don't start antimicrobials until at least even with the aid of magnesium oxide or something, I get their bowels moving, because if you add in antimicrobials in a really constipated system, you really are begging for a Herxheimer reaction because the river is not flowing, there's algae growing, it's muddy, it's not moving, it cannot clear out these toxins. I get the system ready before I add in antimicrobials. Mason: (36:06) That's the most important part, is getting the river flowing. Nirala Jacobi: (36:11) If you're constipated. Mason: (36:11) If you're constipated. Nirala Jacobi: (36:12) Yeah, I would say that that's often when people feel really horrible, when they start something like that and it's just not working. It's ironic because with these archaea or these methanogens as we call them, these organisms that produce methane, once it's actually reduced by the help of antimicrobials, you can expect that the bowel returns to normal, but you can't expect it if you're using some form of garlic extract to combat your methanogens. It will take you a couple of months, or if not longer, to really reduce that level to such an extent that you can have spontaneous bowel movements. Mason: (36:53) What antimicrobials are you normally using? Nirala Jacobi: (36:57) When we talk about treatment, there's three kinds. You have your herbs. You have your conventional antibiotics, and these are very specific antibiotics that are not for ear infections or sinusitis. Then you have a third treatment called the elemental diet. Herbs are usually berberine-containing plants, some essential oils like oregano, clove, those kinds of things. There's a bunch of herbs that I use and an extract or a low-fructans kind of garlic. Garlic typically is a FODMAP food, but if we use it with a high-allicine content, we can use quite a lot of it without a problem for these archaea, and we know that they're really effective for that. Then when you look at antibiotics, you're looking at rifaximin, which is a type of antibiotic that stays in the small intestine, doesn't get absorbed, and it's bile-soluble so it works in that perfect environment. Mason: (37:57) Like the way doxycycline works, I think. Nirala Jacobi: (38:00) No, doxy is way more broader and you will absorb some of that. Rifaximin is not absorbed. It stays in the upper gut. Then you have neomycin for the methanogens. Some people use metronidazole or Flagyl, and I shy away from that because I think as practitioners, we're the custodians of our patient's microbiome and we have to really respect that. Some people, I have seen some shocking microbiomes, let me tell you, by just looking at stool tests and things like that. Stool tests will not give you any information about the small intestine but, very often, it's not like it's only in the small intestine. Problems continue on with the large intestine. Mason: (38:44) You're going to have an overgrowth most likely in the large intestine? Nirala Jacobi: (38:45) Yeah. I've seen microbiomes that are completely denuded, like a clear-cut rainforest, and you're trying to regrow it and no wonder they're so reactive. You had actually mentioned my last podcast guest on my show was the guy who wrote Fibre Fueled, Dr. B., Dr. Will B. Mason: (39:10) Dr. Will B. Yeah, that's what I call him instead of [mumbling]. Nirala Jacobi: (39:11) Bulsiewicz. I think it's Bulsiewicz. Mason: (39:15) Yeah, I can never... We were in Arizona. Nirala Jacobi: (39:19) Oh, right. Mason: (39:20) I met him at the mindbodygreen weekend. We had a we called it dads gone wild night... Nirala Jacobi: (39:28) Oh, do tell. Do tell. Mason: (39:29) Yeah, it wasn't that exciting. It was just me, the DJ, and Dr. B just having chats about the gut and veganism and getting on the gluten-free beers. Nirala Jacobi: (39:44) All right. That sounds like a hell of a party. Mason: (39:49) Yeah, it actually was. I think tequila made its way at some point, which is wonderful. Nirala Jacobi: (39:54) You were in Arizona after all. Mason: (39:55) Exactly. Nirala Jacobi: (39:56) Anyway, I really appreciated having him on the show because here he was, a gastroenterologist, epidemiologist, highly, highly trained specialist, and he had a sort of "Come to Jesus" moment when he really started to study the microbiome and started to work on it for himself. Now, he's like a complete convert about protecting the microbiome and regrowing it. I just think he's done a really good job with that book. Mason: (40:25) Is that where his book is coming from? From that angle or- Nirala Jacobi: (40:28) Fibre Fueled, yeah. I'm not his publicist, but I have the book and I read it and it's pretty good. Half the book is recipes, so vegan recipes, and how to regrow it. One word of caution, don't start with SIBO with that. We had this conversation. You can listen in on The SIBO Doctor podcast if you want to listen to the Feeding Your Microbiome. That shift is slowly happening. There's a lot more respect for the microbiome. I know of a lot of physicians who look back on medicine, on what it's done with antibiotics with real regret of like this was the wrong thing to do to just prescribe amoxicillin for every child's ear infection, or to prescribe for sinusitis, for these types of things. Still, to this day, it's happening day in, day out not just here but across the world where it's just way over prescribed, and it will catch up with you. Mason: (41:33) It's an important part of any practitioner's arsenal to be able to reflect on what they're doing and not be too concrete and make sure you don't have too much morality and judgement of yourself if you did just follow the doctrine at the time, but make sure you've got the capacity to... motility to actually move on to what's important, because I know I wasn't really up on the conversation on testing the microbiome and I think we were chatting about that. Mason: (42:01) Since then, I've got a naturopathic friend who he's basically moved a huge amount of his practise over to testing the microbiome and talking about how it takes out a lot of the guesswork, not only is it the antibiotics and seeing exactly the effect that they're having, which is great as well because you know what you've wiped out, but just dietarily as well, if it's vegan, high-carb, if it's carnivore or just high ... Whatever it is. Nirala Jacobi: (42:32) Yeah, carnivore, I would never promote. Never because it is so hard on the microbiome. It just is. That's basically just meat, and unless you live in countries where, for centuries, that's what you did and I just ... Anyways, that's digressing but they are, and we agreed on that. We totally agreed that most diets, really if it already has a diet, then it's a fad mostly. What we know is where people live the longest and, to me, that's evidence and that's the Blue Zones. Nirala Jacobi: (43:14) That's Dan Buettner's work. He wrote a book called the Blue Zones where people lived to be the oldest in the world, fully functional, still doing their daily work, very cognitively attentive, and very happy. There were seven hotspots in the world. They all had different things, but what they all had in common was 80% plant-based diet. For me, I'd go by that. I'd go by that. If people do well on veganism, then do that because the more plants you can eat, the more diverse your bacterial blueprint will be. Mason: (43:56) That's always with the Blue Zones. Yeah, I first heard about it ... The book I got was Healthy Till 100, I believe it was. That book included a couple of other places. I'll put it in the show notes, guys, the scientifically proven secrets of, I think, the world's longest living people. Vilcabamba was in there in Ecuador, which I think isn't in there with Dan's work but, otherwise, it's like Okinawa, Sardinia. Nirala Jacobi: (44:26) Yeah, and Loma Linda which is like eating processed vegetarian food. Mason: (44:33) I think that their faith gets involved. Nirala Jacobi: (44:33) Yeah, I don't know, but they got there in there, Sardinia. Mason: (44:37) Maybe they're just right. Nirala Jacobi: (44:38) Maybe. Well, who knows? Mason: (44:40) Maybe their prayers are just better than health. Nirala Jacobi: (44:41) Yeah, respect Loma Linda, California. Mason: (44:44) Oh, that's right, John Robbins was the author of that book I was talking about. I like him. He balances out, because I think the thing with Dan's work which always I'm like, "So good," then he's like ... because I'm only talking about his behalf and it's like because it's 80% to 90% plant food and then 100% is the obvious conclusion, which I don't find to be the obvious conclusion. Nirala Jacobi: (45:09) No, because I think and I will say if you look at the standard bi-phasic diet just to keep it in the SIBO spectrum, the standard bi-phasic diet is very animal protein heavy. Then I created a vegetarian bi-phasic diet, which is very amenable to vegans, and it's not just about taking the meat. That was a lot of work that I co-authored that with our clinical nutritionist, Anne Criner, here at our clinic. Then we have a third one which is the histamine bi-phasic. But there is something. Nirala Jacobi: (45:41) A lot of people have tried veganism and it's just like, constitutionally, they just couldn't do it. I don't know what the answer is for those people because there are some people that just they get weak. Dr. B would probably argue that he thinks that everybody can live like ... I think, I shouldn't speak for him, but I don't know. I find that everybody is a bit different. Mason: (46:09) Yeah, I'm with you as well. I find if you take one part of the body and solely focus on it, same if you're only focusing on the large intestine and the microbiome and not cellular, in particular cellular markers, then I can see how it would be really easy to justify a vegan diet. I was vegan and raw foodist for quite a while and then moved away from that direction and just was really questioning my need to eat a certain amount of domesticated vegetable and fruit matter. Mason: (46:46) Then once I got back into the microbiome, I've really come to peace and to terms with the fact that, "No, you know what, that's ..." I was really rocking. I was rocking with that majority of my well-being, and even moving back into lentils and legumes and beans, which had a huge chip on my shoulder about. But then just staying open to ensuring there's potentially ... Like in the Blue Zones, meats are normally a side dish, and I like that. Nirala Jacobi: (47:15) Yeah. I do, too. I know myself, I haven't eaten red meat in 40 years probably but I eat chicken occasionally. That's my one and only animal that I eat because also the carbon footprint. It's whole 'nother conversation, Mason. Nothing to do with SIBO. But in a nutshell, the diet is a therapeutic diet. It's not a stay-on-it forever diet. Mason: (47:40) Greaaaaat distinction. I'm going to have to get excited about the diet. I'm going to have to get my mum, because I'll let you all know how. Maybe if I can have a chat again, get you back on here after, I'm going to use all your resources, all the listeners are going to ... I'll keep you in the loop of where mum's at, especially. Nirala Jacobi: (48:02) Sure. Mason: (48:03) Yeah, I'll let you know on an intro at some point where she comes back with in the test. If it's positive, then we'll go on that journey together. With meat and impact. Have you tried a wild, invasive deer or anything from around here. It's like- Nirala Jacobi: (48:21) No, but I'm not opposed to it. I trust my body and I just have no affinity towards those things. Red meat, just no. Mason: (48:35) Yeah, that's fair enough. Nirala Jacobi: (48:38) We're really covering a lot of ground, but there's something about the whole blood type thing that I can tell you as a practitioner, that's been nearly a quarter of a century in practise that there's something about that. Blood type As tend to have a little bit harder time with digesting animal protein. Mason: (48:58) Is that just going back to the classic book, The Blood Type Diet? Nirala Jacobi: (49:02) Dr. D'Adamo. Mason: (49:03) Yeah, D'Adamo. That's right. Nirala Jacobi: (49:06) Yeah. Look, it's still got work to do, but I think there's elements that I certainly have seen be proved in practise. For me, I don't just need theories, I actually need evidence. For me, evidentially, I have seen that in practise, that people that are blood type O, they fade sometimes on a vegan diet because I don't know. I never got so fully into it that I can rattle off the science right now, but it has to do with rhesus factor and different ... Well, the theory was really that when we originated ... See, an evolution story. Nirala Jacobi: (49:47) When we originated in Africa, everybody was blood type O because you needed to be able to eat dead animals and stuff. You had a very forgiving type of blood type that was not very reactive. Then as we moved north and into Europe, it wasn't really economical to eat your animals, and so you became more farmers and started to grow things, and that was blood type A. Then as you move further north, you had natural refrigeration, and that was the AB type or the B type, which can handle dairy really well. That's the theory anyways. I can tell you that much. Mason: (50:22) It's a good theory. Nirala Jacobi: (50:23) It's a good theory. Mason: (50:23) That was always the thing with The Blood Type Diet. Nirala Jacobi: (50:26) It checks out. Mason: (50:27) It checks out. I remember The Blood Type Diet was a funny one because every practitioner I've talked to has said there is something to this- Nirala Jacobi: (50:35) Yeah, there's something to it. Mason: (50:36) But the science was never rock solid so it was open for criticism, yet anecdotally, it was on point. I love it. It's good to know. It's good to go into that world because as soon as you get into, as you said, you made that decision, it's why it's hard sometimes to listen to a practitioner talk about diet long-term because you know that the mindset is based on healing. Then as you said, this is a healing- Nirala Jacobi: (51:03) Therapeutic. Mason: (51:03) Therapeutic diet. Huge distinction because, otherwise, you stay in a "I'm sick" mentality long-term. Nirala Jacobi: (51:11) Right. Look, I always tell my patients when you travel ... Well, it's a different world now, but if you were going to see Paris, I don't want you on this diet. I want you to eat baguette and dip it in the cafe au lait. I want you to eat things that you enjoy. Most of the time, when people travelling and they suffer from food sensitivity, it actually miraculously goes away. Of course, celiac disease is a different story, but there is this element of you just having just more endorphins and your secretory IgA goes up and all of that, and people can tolerate a lot of foods that they would not normally tolerate in a happy setting and a happy live-your-life, I want you to drink wine if you're in Italy. Why restrict ourselves to this myopic thinking, it has to look this way? Mason: (52:03) It's refreshing. I like the way that you're bridging over there. It's something that I've always liked about your accessible approach because it's like bridge into what's actually going on and then I'm going to see your bridge out over there to live your life because, obviously, people do get addicted to being sick and something being wrong and then the fear of if I do something outside of the therapeutic- Nirala Jacobi: (52:23) There's a lot of fear. There's a lot of food fear and there's this whole new term of orthorexia. Mason: (52:29) Yeah, exactly. Nirala Jacobi: (52:30) That's a real thing. A lot of people are so concerned about having made some small error on the bi-phasic diet. I'm like, "You've made no error. It's fine." Not just the bi-phasic diet but also anything, really. They get very, very hooked on that they did something wrong, and there's a lot of food fear and that. Imagine, you're sitting down to eat your meal and you're already worried about the food. Sometimes, I tell people sit for two minutes and just appreciate the food, just take a moment and get into a rest and digest before you eat. Mason: (53:13) That's where the prayer comes in, the grace. Nirala Jacobi: (53:16) It used to be prayer, it used to be grace, all of that. That's all. It's a thing. Mason: (53:21) I feel like we go down this rabbit hole, that's probably another podcast talking about the orthorexia. I know it very well. I've had to go. I was so down the rabbit hole of raw foodism. I had to go and start eating things that I swore I would never eat again to start cracking myself out of just like that scrubbing myself clean with my diet. It's hardcore, and it isn't orthorexia, and it isn't eating disorder in varying degrees. But thanks for bringing it up, because especially when you're promoting a therapeutic diet, I always think the duty of care comes with making sure that people and patients are aware not to get stuck in it. Thank you for that. Nirala Jacobi: (54:00) My pleasure. Mason: (54:02) I had really a lot of fun chatting with you. Nirala Jacobi: (54:03) I did, too. We've covered a lot of ground. Mason: (54:06) We've covered a lot of ground. We run really fast on this podcast. Look, let's just repeat it again. The SIBO Doctor podcast, and it was episode 64 and 65 that we just talked about with Dr Will B. Worth probably checking out. Nirala Jacobi: (54:26) It's on iTunes. It's on everywhere. You can go to The SIBO Doctor and just look around. There's resources. All the guides are free downloads, the handout on bringing that to your practitioner in terms of what caused you SIBO. It's a free download. There's a lot of videos, lots of stuff. I'm on Instagram, Dr. Nirala Jacobi, the SIBO Doctor. Mason: (54:46) Perfecto. Thank you so much. Nirala Jacobi: (54:48) Boom. Mason: (54:49) Boom. Nirala Jacobi: (54:50) Mic drop. Mason: (54:52) All right. All right. That didn't work. That was a terrible mic drop. Nirala Jacobi: (54:55) No, that's a very sensitive, very fancy road microphone.
Become an expert on bifidobacterium and beneficial gut bacteria. Listen to this episode for the ultimate crash course on bifidobacterium. Learn about everything possible related to bifido, citing studies and more.
In part two of our episode with Ali Miller, RD from AliMillerRD.com we discuss considerations for cesarean births including: concerns for mom and baby, how to address these concerns with a food-as-medicine approach, vaginal inoculation, and tips for a speedy recovery! Ali shares her story of home birth turned hospital cesarean and how she took action to ensure optimal health for herself and her baby, Stella. It's a truly inspiring story! Because our conversation was jam-packed with resources to support those planning or recovering from a cesarean birth, we decided to split the episode into two parts. That way, you'll be able to take in all of this great information without feeling overwhelmed (in a good way!). Topics discussed in Part 1 (episode 69): Ali's story Her original birth plan and how that changed How she managed the change in birth plan (emotionally, mentally, physically) The differences between a gentle (or natural or family-centered) cesearean and a traditional cesarean Topics discussed in Part 2 (episode 70): Concerns of cesarean sections How to address these concerns with a food-as-medicine, functional medicine approach Considerations for mom and baby Vaginal inoculation and supplements Low-carb, moderate protein, high-fat diets during pregnancy and nursing How Ali feeds her toddler Ali's practice, cookbook, and services Ali's bio: Ali Miller is an integrative functional medicine practitioner with a background in naturopathic medicine. She is a Registered and Licensed Dietitian, Certified Diabetes Educator, certified weight management specialist, recognized leader, speaker, educator, and advocate in her field. Ali has a passion to create public awareness regarding the significant role diet plays in our overall health and believes everything we put in our body can contribute towards optimal health or dysfunction and disease. Her Food-As-Medicine philosophy is supported by up-to-date scientific research for a functional approach to healing the body. Ali’s message has influenced millions through media with weekly television segments, corporate outreach and within the medical community, and named one of Houston's 50 most influential women of 2015. Ali’s expertise can be accessed through her website: www.alimillerRD.com offering a blog, podcasts, online learning, and access to her practice in Montrose, Naturally Nourished. Enjoy the listen! Click here to listen or find the podcast on iTunes or Stitcher! Shownotes: AliMillerRD.com Naturally Nourished: Food-as-Medicine for Optimal Health cookbook Supplements mentioned on podcast: Upspring Well-Baby multi-vitamin (baby) Metagenics UltraFlora probiotic (baby) Nordic Naturals EPA/DHA (baby and mom) Systemic Enzyme Complex by Pure Encapsulations (mom) Basic Prenatal by Thorne (mom) S-Acetyl Glutathione with NAC (mom) 60 billion blend of Bifido and Lactobacillus-based probiotic and a wide spectrum blend of 20 billion strains (mom) Steph’s Healthy Mama, Happy Baby Virtual Pregnancy Handbook Disclaimer Please remember that the views on this podcast and website are not meant to be substituted for medical advice, shouldn’t be used to diagnose, treat or cure any conditions, and are intended for general information purposes only.
In this episode, Stephanie interviews Ali Miller, RD from AliMillerRD.com to discuss considerations for cesarean births including: the mental and emotional side of changing your birth plan, concerns for mom and baby, and tips for a speedy recovery! Ali shares her story of home birth turned hospital cesarean and how she took action to ensure optimal health for herself and her baby, Stella. It's a truly inspiring story! Because our conversation was jam-packed with resources to support those planning or recovering from a cesarean birth, we decided to split the episode into two parts. That way, you'll be able to take in all of this great information without feeling overwhelmed (in a good way!). Topics discussed in Part 1: Ali's story Her original birth plan and how that changed How she managed the change in birth plan (emotionally, mentally, physically) The differences between a gentle (or natural or family-centered) cesearean and a traditional cesarean Topics discussed in Part 2: Concerns of cesarean sections How to address these concerns with a food-as-medicine, functional medicine approach Considerations for mom and baby Vaginal inoculation and supplements Low-carb, moderate protein, high-fat diets during pregnancy and nursing How Ali feeds her toddler Ali's practice, cookbook, and services Ali's bio: Ali Miller is an integrative functional medicine practitioner with a background in naturopathic medicine. She is a Registered and Licensed Dietitian, Certified Diabetes Educator, certified weight management specialist, recognized leader, speaker, educator, and advocate in her field. Ali has a passion to create public awareness regarding the significant role diet plays in our overall health and believes everything we put in our body can contribute towards optimal health or dysfunction and disease. Her Food-As-Medicine philosophy is supported by up-to-date scientific research for a functional approach to healing the body. Ali’s message has influenced millions through media with weekly television segments, corporate outreach and within the medical community, and named one of Houston's 50 most influential women of 2015. Ali’s expertise can be accessed through her website: www.alimillerRD.com offering a blog, podcasts, online learning, and access to her practice in Montrose, Naturally Nourished. Enjoy the listen! Click here to listen or find the podcast on iTunes or Stitcher! Shownotes: AliMillerRD.com Naturally Nourished: Food-as-Medicine for Optimal Health cookbook Supplements mentioned on podcast: Upspring Well-Baby multi-vitamin (baby) Metagenics UltraFlora probiotic (baby) Nordic Naturals EPA/DHA (baby and mom) Systemic Enzyme Complex by Pure Encapsulations (mom) Basic Prenatal by Thorne (mom) S-Acetyl Glutathione with NAC (mom) 60 billion blend of Bifido and Lactobacillus-based probiotic and a wide spectrum blend of 20 billion strains (mom) Steph’s Healthy Mama, Happy Baby Virtual Pregnancy Handbook Disclaimer Please remember that the views on this podcast and website are not meant to be substituted for medical advice, shouldn’t be used to diagnose, treat or cure any conditions, and are intended for general information purposes only.
Lauren Petersen, PhD, is a postdoctoral associate working for Dr. George Weinstock and investigating the microbiome. Our knowledge of the 100 trillion microorganisms that inhabit the human body is still very limited, but the advent of next-generation sequencing technology has allowed researchers to start understanding what kind of microorganisms inhabit the human body and identifying the types of genes these organisms carry. As part of the NIH-funded Human Microbiome Project, her lab is focused on developing and applying the latest technologies to characterize the microbiome and its impact on human health. One of her main projects is metatranscriptomic analysis whereby they are attempting to characterize gene expression of an entire community from human samples such as stool and saliva. Gaining information on what signals or environmental factors can trigger changes in global gene expression of an entire microbial community may provide us with the tools to better treat certain types of diseases in humans. Lauren is currently working on the Athlete Microbiome Project. By collecting stool and saliva samples from a cohort of highly fit professional cyclists, she will make an attempt to understand how their microbiomes may differ from those of the general population. The goal is to characterize the species present, the genes they carry, and how gene expression is modulated in athletes who push their bodies to the limit. Here’s the outline of this interview with Lauren Petersen: [00:00:28] George Weinstock, PhD. [00:01:27] Jeremy Powers interview. [00:01:43] Jeff Kendall-Weed. [00:02:15] Why care about the gut microbiome? [00:03:32] Metabolic functions. [00:03:51] NIH Human Microbiome Project. [00:04:39] Phase II longitudinal study. [00:06:01] Microbial diversity. [00:07:33] Lyme and antibiotics. [00:08:15] Chronic Fatigue Syndrome. [00:09:35] Gordon conferences - Rob Knight. [00:10:27] American Gut Project. [00:10:48] Firmicutes and Bacteroidetes. [00:11:05] Enterobacteriaceae. [00:11:59] Fecal transplant. [00:13:16] Screening donors. [00:13:32] DIY. [00:13:52] C. diff. [00:14:14] Transplants started in the 50s. [00:14:47] IBS. [00:16:12] Healthy donor. [00:17:43] Within a month, Lauren was feeling a lot better. [00:18:13] Instantaneous improvement on the bike. [00:19:22] No more stomach issues, "more energy than I knew what to do with". [00:19:54] Retest data showed perfect match with donor. [00:20:56] Sequencing large vs. small intestinal microbes. [00:21:28] FDA has no idea what to do. [00:23:02] Strategies for maintaining a healthy gut microbiome. [00:23:31] Whole foods, lots of fruit and vegetables. [00:23:48] No gels. [00:24:26] Athlete Microbiome Project. [00:26:34] Microbiome doping? [00:27:05] Ruminococcus - starch digester. [00:28:26] Enterotype - the dominate species in the gut. [00:28:56] Prevotella. [00:30:14] Teasing apart the cause and the effect. [00:32:28] Endotoxins released during intense exercise. [00:32:49] 25 participants at the time of recording, I'm number 26! [00:33:29] Matching cohort of healthy controls. [00:34:28] Ibis World Cup racer. [00:35:01] uBiome. [00:35:08] My app. [00:35:54] The problem with 16S sequencing. [00:36:16] Missing bifidobacteria. [00:37:05] A combination of methods is required for accurate testing. [00:38:30] New commercially available test? [00:39:11] Probiotic quality. [00:40:04] Testing probiotics. [00:41:37] Bifido doesn't like oxygen (or your stomach). [00:42:02] Lactobacillus is more resilient. [00:42:50] Bifido love fructooligosaccharides. [00:43:36] Lack of association with dietary restrictions. [00:44:53] Feed your microbiome!
Infants are bathed in protective, beneficial microflora as they pass through their mother’s birth canal. As a result, babies delivered vaginally are bathed with friendly, protective Bifido bacteria. In contrast, babies delivered by caesarian section (C-section) become bathed in the bacteria from their environment. When this occurs, babies lose out on the benefits that B. infantis supplies. They miss the natural boost to their defenses, and don't receive the digestive support for their inexperienced gastrointestinal tract–not the best start to lifelong health. The post 161 – Infants Need Specific Probiotics – My Interview with Natasha Trenev appeared first on Health Quest Podcast.
Dr. Josephine Yuen is the Ex Dir of E3S Center a collaboration of UCB, MIT, Stanford and UTEP. She is a Physical Chemist, Ph.D. from Cornell. She explains the e3s Center goals, Community College program, and focus on getting the research right.TranscriptSpeaker 1: Spectrum's next Speaker 2: [inaudible] [inaudible]. [inaudible]. Speaker 1: Welcome to spectrum [00:00:30] the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hi and good afternoon. My name is Brad Swift. I'm the host of today's show. Our guest is Dr Josephine u n. She is the executive director of the [inaudible] center, a collaboration of UC Berkeley, MIT, Stanford, [00:01:00] and the University of Texas at El Paso. Dr [inaudible] is a physical chemist by training with a phd from Cornell University and she was also a postdoctoral fellow at the Argonne National Laboratory. She became a member of technical staff in bell laboratories and eventually held director level positions in product development, product management, manufacturing and supply line management. More recently, she was the CEO of try form x INC which develops and manufactures precision polymer [00:01:30] optics for the communications consumer products and medical industries. After spending 30 years in industry, she was a program director at the National Science Foundation. Today she talks with me about the [inaudible] center here at Berkeley, Josephine Ewen. Welcome to spectrum. Speaker 1: Thank you.Speaker 3: What is the origin story of e three s? How did it all get started? Speaker 1: Well, let's first understand what e three s stands for. It's [00:02:00] an acronym and this acronym for a center does headquarted in UC Berkeley and it's the center for energy efficient electronics science. Our story really began at the National Science Foundation. The National Science Foundation has several programs that fund centers intended to bring researchers from many institutions together to solve difficult problems [00:02:30] and one of those programs is the science and Technology Center program. Way Back and I believe most probably was 2008 there was a solicitation asking technical community and that is universities. Did you submit proposals for a new science and technology center? This type of solicitation comes out once every three years or so and so in two and nine professor [00:03:00] [inaudible] off the east department submitted a proposal that brings together researchers from various institutions, namely UC Berkeley, MIT, and Stanford to propose a new center, a new center that will do research necessary to come up with an alternative to the current day trend system. Speaker 1: No, you may want to ask, why do we need that? After all, transistors are everywhere and [00:03:30] it's in every aspects of our life. The reason we need an alternative is that we need an nutrient system or any kind of electronic components that would draw significantly less energy. Pol consumption in electronic devices have been dropping by virtue of the fact that through miniature isolation, the electronic industry has made great gains, not only in power consumption but in the cost of the device, [00:04:00] but unfortunately, miniaturization has hit a brick wall. It no longer is delivering the benefits it has delivered 10 plus years ago and you can see it by the very fact that the operating voltage of those devices in the past 10 plus years ago when the line was shrinks, you can see a big drop in the operating voltage, but in the last 10 years it's more or less flattened out and [00:04:30] even though the line was has shrunk further, we see that the operating voltage is around a vote, maybe slightly less than a vote now in the state of the art devices, but really we want to get to a device that can operate in the millivolt range and that is what the centers set out to do and we're doing the research necessary to get there. [inaudible] Speaker 3: I wanted to have [00:05:00] you talk about the themes of research at e three s and what made choosing themes and appealing method for your organization? Speaker 1: The center is researching different scientific concepts to achieve different device approaches. No one knows what is the best approach at this point. The current c Moss transistor is ubiquitous. There's no reason to believe is replacing will be [00:05:30] equally ubiquitous. The replacement may be a different solution for different application. That's why our research portfolio includes four themes. Not all four themes address the transistor. If you think of a integrated circuit, it's really a network of switches and the wires that connect us, which is three of the themes, address a different [00:06:00] type of switch while one theme address, how do you have more efficient wires or lower power consumption wires? Today's wars are copper wires, metal to wires, but we are doing research to have the communication between switches being done optically Speaker 3: and just for the record, what are the four themes? Speaker 1: The first theme is Nano Electronics. [00:06:30] The second theme is Nano mechanics. The third theme is nanophotonics and the fourth theme is Nano magnetics and you can see the first, second and fourth addresses. How do you get a different type of switch? While the third theme addresses the interconnection, namely the use of light for the interconnection amongst the switches [00:07:00] that we also call optical interconnect. Speaker 3: How interdisciplinary is the center? Do you have a sense of that in terms of the investigators and the researchers? Speaker 1: The center is highly into disciplinary disciplines involved. Our electrical engineering, chemistry material science and Physics Speaker 4: [inaudible]Speaker 3: [00:07:30] you are listening to spectrum of public affairs show on k a l x Berkeley public. Our guest is Josephine n. She is the executive director of the three s center. In the next segment she details the e three s community college outreach group. [inaudible]. An [00:08:00] interesting part of the e three s center is the program you've developed with community colleges. Do you want to explain how that program began and what its goals are? Speaker 1: A science and technology center is expected to educate besides do research and the education is not only have graduate students, so in I'll propose which NSF we decided to focus [00:08:30] on community college students. The reason we decided to do that is because in California we have the largest community college system in the country and many women and underrepresented minority start their post high school education. In community colleges. Our needs to increase its output of workers in this fuse [00:09:00] state utilizes science and technology disciplines and in order to do that we have to be able to encourage and groom participants from populations that are typically underrepresented in the technical world and this really based on that consideration that we say less focus on encouraging students, helping students from community colleges [00:09:30] develop a career in science and engineering. Speaker 3: What can you tell me about how the program is working and how people participate in it? From the community college side, Speaker 1: we have a program on campus called the transfer to excellence and this program while started by the East Rehab Center has now expanded to include other centers. This has been made possible because in addition to [00:10:00] the east area centers grind, the National Science Foundation also gave us an additional three years grant to expand the community college program and that has allowed the program to place students not only in the [inaudible] center but also to other centers on campus. Namely coins, the deals with Nana mechanics and also [inaudible] that deals with [00:10:30] synthetic bio fuse. The students from community college come on campus in the summer for nine weeks to do research, the first weakest bootcamp with the learn some of the basics to prepare them to go into the labs and then for the other eight weeks they work in the lab on individual projects and at the end, in the last week of the internship, they have to [00:11:00] present their work both in terms of giving talks and also in the form of posters in a poster session and that typically takes place at the beginning of August. And how large is that program? Last summer we hosted approximately 15 students. Speaker 3: Does that sort of what your target is for each summer? Speaker 1: Yes. Between 12 to 15 is off target [inaudible]. Speaker 3: And how do people [00:11:30] in community colleges get involved in it? How do they get selected or how do they apply? Speaker 1: In the fall we go through what we consider our recruitment face. We Post the information about the program on the website of our center. The staff of the center also goes out on campus to recruit. We host workshops to share information about a program and also to provide pointers to potential [00:12:00] applicants, how best to prepare the application. We also have webinars with, again, the purpose of encouraging and guiding potential applicants and how to apply and we also work with various community college or Nay stations to promote the program. For example, we ran a workshop in a Mesa conference. Is it statewide? [00:12:30] Yes. We're very proud to say that we have brought students from Mount Shasta down to south of San Diego from the bay area to the central valley Speaker 3: and I suppose the hope is that the students will then go to four year colleges get degrees. Are you tracking at all their progress in that effort? Speaker 1: Yes. Clearly the number one goal of this program [00:13:00] is to use research to deepen the interests of these students in science and engineering and you can ensure that they will get a good career in science engineering. Minimally a four year degree is necessary, so helping the students to transfer to a four year institution is number one goal. In addition, we want to excite them enough that they would even set this sites to go to graduate [00:13:30] school. The program provides one on one advising on the transfer process, particularly to UC Berkeley but also to four year institution in general and this advising is done by tap advices, which is the transfer alliance projects. There's part of UC Berkeley's campus, 87% of our 2012 class has transferred [00:14:00] to to what you see last fall. Most of them came to UC Berkeley, but others went to other ucs as well and I believe one of them actually transferred to Columbia Speaker 3: and for students that are in community colleges it might be listening. The best way to find out about it is to go on your website. Speaker 1: Yes. That's the best way to find out about the program and is also through our website which is www.ethrees-center.org [00:14:30] this website not only provides information but it just through this website you do your online application, Speaker 3: the community college students that are coming, what are their science requirements? Speaker 1: The program takes students the summer before they apply to transfer to a four year institution. By then we expect the students [00:15:00] to have completed two calculus courses and three signs or engineering courses including one laboratory course. Speaker 2: Okay. Speaker 5: From is a science and technology show on KALX Berkeley. We are talking with Josephine. You went [00:15:30] in the next segment she talks about the hope of research migrating from the lab to Congress. Speaker 2: [inaudible]Speaker 3: the center's focus now is on research. Is there at some point if you're successful with your research, a capability to implement and build something that would be a prototype of sorts. Speaker 1: [00:16:00] We are very much in the science face of our center. As a matter of fact, we are very much encouraged by our funder to really focus on understanding the science as opposed to just using empirical methods to achieve device demonstration. Part of the center's strategic plan costs for at the end of our sentence life, which we expect to be 10 years. We will be [00:16:30] able to have one technology, namely our science will be mature enough that we have a technology that can be commercialized. On the other hand, we are expected along the way to be able to really understand how realistic our approaches so we will be expected to have certain types of prototype demonstration in the second five years [00:17:00] of our center. Also each theme we expect that I'll research may have some near term applications and actually as a example in theme three which is the Nanophotonics we expect that I'll work in photo detectors can have near term applications. Speaker 3: So in a sense kind of spinning off some of the early successes within the center or do you have to move it out of the center to other [00:17:30] players? Speaker 1: They have different ways of transferring the knowledge that we gained through our research. The center has industry partners. This industry partners are leaders in the electronics industry. They have recognized the neat off the center and we should clearly we see them s one of the avenues to transfer technology that Nia term along the term [00:18:00] technologies that may come after center, but as you know, they also many other venues including potentially some of our students taking technologies and creating companies [inaudible] Speaker 3: so the industry partners also are able to feed back to you, give you some reflection on your research. Speaker 1: The feedback will enable the center to conduct this research to be practical and useful Speaker 3: [00:18:30] with the publications. Are there any restrictions on who you can publish with? Are you seeking out open source journals? Speaker 1: The Sentis research results are publish through peer review journals. Many of these journals, one could argue is not open source because you need a subscription to get to them. However, the journals allow the authors to post the papers on [00:19:00] their own website. I'll send to identifies on our website, our list of publications and through the authors own website, the public can gain access to those papers. Speaker 3: Are there other centers or other research groups that are doing very similar work that you pay close attention to? Speaker 1: Yes, there is a center in Notre Dame that [00:19:30] is partially funded by DARPA and another government agency. That center involves not only Notre Dame, Bifido is headquartered there, but it also has members from many of the academic institutions. The name of the center is leased. The center has similar goals as us. We are not the only people that recognized the problem the semiconductor industry is facing, [00:20:00] so there are many efforts and many researchers around the world working on different approaches to solving the problem. We are one of several centers. We believe we differentiate ourselves in part because we have really put a strong emphasis on establishing the science and understanding what has prevented an easy solution. Speaker 3: In your personal [00:20:30] story, you've spent some time on both sides of the granting process being with the NSF. What does it like seeing both sides of the process?Speaker 1: I was the SPI, our program officer at the National Science Foundation before coming to UC Berkeley at the Star Center. A programs officer's job is to figure out what area to fund. And in conjunction with review panels, recommend [00:21:00] which particular proposals you fund. And then after the award, the program office is job is to advise, guide, oversee the delivery of results and ensure that the grantee is in compliance with the program requirements. But when you are grantee, your job is to deliver on what you promise. So a lot of the focus is on results delivery [00:21:30] while a programs office job is to facilitate guide help, but not directly involved with the results delivery [inaudible] which do you prefer? My background prior to going to national science foundation was in private industry. So I have a very strong operating background. So to a certain extent, one can argue that given the number of years I've spent [00:22:00] operating or delivering results, that comes to me more naturally. Speaker 6: Josephine n, thank you very much for coming on spectrum. Speaker 1: Thank you for having me. Speaker 2: [inaudible]Speaker 5: for more details [00:22:30] on the [inaudible] center and their educational program, which covers pre college undergraduate, graduate and postdoc opportunities. Go to the e three s website, which is e three s-center.org spectrum shows are archived on iTunes university and we have created a simple link to help you get there. The link is tiny url.com/kalx [00:23:00] spectrum Speaker 2: [inaudible].Speaker 5: We hope you can get out to a few of the science and technology events happening locally over the next two years. Two weeks. Speaker 6: Renee Rao and chase Jacabowski present the calendar this Monday, February 24th come check out the next edition of nerd night. East Bay featuring lectures such as explosions, [00:23:30] back drafts and sprinklers, how Hollywood gets fire science wrong by Joel Sipe. Then listen to Brian Dote from sweet Mary's coffee and he'll show us how a cherry becomes black gold in his lecture home coffee roasting on the with tools you probably already have and last Vincent tank way will teach us about hyper velocity launchers in his lecture. Hyper velocity launchers, how to launch a projectile at 10 meters per second. That's right. 10 meters per second. Once again, nerd night takes [00:24:00] place. February 24th at the new parkway cinema in Oakland. Doors Open at 7:00 PM on Monday, March 3rd Dr. Edward Stone of Caltech will be giving a talk about the voyager spacecraft missions into interstellar space launched in 1977 to explore Jupiter, Saturn, Uranus, and Neptune. The two voyager spacecrafts continue their journeys as they search for the Helio pause. Speaker 6: The heliopause is a boundary between the solar wind and the local interstellar medium. [00:24:30] Recently in August, 2012 voyager one seem to be finally entering into the heliopause. The spacecraft reported finding depleted low energy particles originating from inside the heliosphere as well as low energy cosmic rays from nearby regions of the Milky Way. These in subsequent observations of the heliopause are revealing new aspects of the complex interaction of our son with a local interstellar medium to hear a complete history and learn where the voyager is. Now. Join Dr. Stone on [00:25:00] March 3rd at 4:15 PM in [inaudible] room number one on my name, March 3rd at 7:30 PM hello fellow Dr Jacqueline. Ferritin will speak in the planetarium of the California Academy of Sciences. At the close of 2013 the Italian stars with planets orbiting them toppled more than 1000 the majority of these so-called exoplanets have not actually been seen, but rather inferred from their effect on their host stars through pain seeking technical methods and tremendous telescope [00:25:30] 10 handful of indirectly image and these giant planets have shown fascinating diversity in their sizes, temperatures, weather, and relationships to their parents. Speaker 6: Sends over the past several years, an entirely new and mysterious breed of planets has emerged. As genres have discovered a collection of orphans. Planets that are moving through the galaxy, seemingly unattached to a star in this talk fairly will highlight how we discovered these seemingly impossible objects and review how these strange, exotic planets may be key [00:26:00] players in our understanding of planet formation and evolution. Her talk will be held seven 30 on Monday night, March 3rd go to cal academy.org to reserve tickets. A feature of spectrum is to present new stories we find interesting. Tracy Jakubowski and Renee Rao present our news, the deal. Cal reports a new project from UC Berkeley. Researchers may soon allow the power of ocean waves to join solar and wind power as a commercialized source of energy. [00:26:30] The project is led by Marcus Lehman, a visiting graduate student in the Mechanical Engineering Department and supervised by razor alum and assistant professor of mechanical engineering and principal investigator of the research. Speaker 6: The project focuses on building a prototype of a sea floor carpet that can generate electricity by mimicking the properties of the muddy sea floor. Therefore, the group is designing a c floor carpet waive dampening system that will harness the energy of waves passing over it. Theoretically, the [00:27:00] energy generated by 10 meters of sea floor carpet will be roughly equivalent to the energy conducted by a stadium sized soccer field completely covered by solar panels. As more and more people move to live near coastlines, the researchers expect wave power to be a top contender as the next big renewable resource, especially because waves have very high energy density. The cost of building devices to harness wave power is high. LM said, the ocean is a difficult place to work and our devices have to be sturdy enough to combat [00:27:30] the oceans, corrosive and harsh environments, but there's an increasing need for clean and as socially acceptable forms of generating power. Speaker 6: We're working hard with scientists and engineers to make this happen and it's only a matter of time. A recent study published in the Open Access Journal microbiome examine the GI tract of premature infants in the neonatal intensive care unit or NICU. The lead author of the study, Brandon Brooks, a graduate student in the plant and microbial biology department at UC Berkeley, collaborated [00:28:00] with researchers university of Pittsburgh to swab the most touched surfaces at the NICU, as well as collect samples from two premature babies. In a small pilot study, they discovered the microbial environment of the baby's GI tracks was strikingly similar to that of the NICU, which was particularly interesting given that the premature babies were treated with antibiotics and should have had a very limited diversity of micro organisms within their GI tract. Well, most of the micro organisms were opportunistic. A few contain genes that conferred resistance [00:28:30] to antibiotics and disinfectant that was used within the NICU. The study provided an important insight into how the pathogenic, as well as nonpathogenic organisms are able to move from even the most sterile of environments to our bodies. Speaker 4: [inaudible] [inaudible] Speaker 7: the music heard during the show was written and produced by [00:29:00] Alex Simon Speaker 8: [inaudible].Speaker 7: Thank you for listening to spectrum. If you have comments about the show, please send them to us via email or email address, spectrum dev, QA, and lex@yahoo.com genus in two weeks time. [inaudible]. See acast.com/privacy for privacy and opt-out information.
Dr. Josephine Yuen is the Ex Dir of E3S Center a collaboration of UCB, MIT, Stanford and UTEP. She is a Physical Chemist, Ph.D. from Cornell. She explains the e3s Center goals, Community College program, and focus on getting the research right.TranscriptSpeaker 1: Spectrum's next Speaker 2: [inaudible] [inaudible]. [inaudible]. Speaker 1: Welcome to spectrum [00:00:30] the science and technology show on k a l x Berkeley, a biweekly 30 minute program bringing you interviews featuring bay area scientists and technologists as well as a calendar of local events and news. Speaker 3: Hi and good afternoon. My name is Brad Swift. I'm the host of today's show. Our guest is Dr Josephine u n. She is the executive director of the [inaudible] center, a collaboration of UC Berkeley, MIT, Stanford, [00:01:00] and the University of Texas at El Paso. Dr [inaudible] is a physical chemist by training with a phd from Cornell University and she was also a postdoctoral fellow at the Argonne National Laboratory. She became a member of technical staff in bell laboratories and eventually held director level positions in product development, product management, manufacturing and supply line management. More recently, she was the CEO of try form x INC which develops and manufactures precision polymer [00:01:30] optics for the communications consumer products and medical industries. After spending 30 years in industry, she was a program director at the National Science Foundation. Today she talks with me about the [inaudible] center here at Berkeley, Josephine Ewen. Welcome to spectrum. Speaker 1: Thank you.Speaker 3: What is the origin story of e three s? How did it all get started? Speaker 1: Well, let's first understand what e three s stands for. It's [00:02:00] an acronym and this acronym for a center does headquarted in UC Berkeley and it's the center for energy efficient electronics science. Our story really began at the National Science Foundation. The National Science Foundation has several programs that fund centers intended to bring researchers from many institutions together to solve difficult problems [00:02:30] and one of those programs is the science and Technology Center program. Way Back and I believe most probably was 2008 there was a solicitation asking technical community and that is universities. Did you submit proposals for a new science and technology center? This type of solicitation comes out once every three years or so and so in two and nine professor [00:03:00] [inaudible] off the east department submitted a proposal that brings together researchers from various institutions, namely UC Berkeley, MIT, and Stanford to propose a new center, a new center that will do research necessary to come up with an alternative to the current day trend system. Speaker 1: No, you may want to ask, why do we need that? After all, transistors are everywhere and [00:03:30] it's in every aspects of our life. The reason we need an alternative is that we need an nutrient system or any kind of electronic components that would draw significantly less energy. Pol consumption in electronic devices have been dropping by virtue of the fact that through miniature isolation, the electronic industry has made great gains, not only in power consumption but in the cost of the device, [00:04:00] but unfortunately, miniaturization has hit a brick wall. It no longer is delivering the benefits it has delivered 10 plus years ago and you can see it by the very fact that the operating voltage of those devices in the past 10 plus years ago when the line was shrinks, you can see a big drop in the operating voltage, but in the last 10 years it's more or less flattened out and [00:04:30] even though the line was has shrunk further, we see that the operating voltage is around a vote, maybe slightly less than a vote now in the state of the art devices, but really we want to get to a device that can operate in the millivolt range and that is what the centers set out to do and we're doing the research necessary to get there. [inaudible] Speaker 3: I wanted to have [00:05:00] you talk about the themes of research at e three s and what made choosing themes and appealing method for your organization? Speaker 1: The center is researching different scientific concepts to achieve different device approaches. No one knows what is the best approach at this point. The current c Moss transistor is ubiquitous. There's no reason to believe is replacing will be [00:05:30] equally ubiquitous. The replacement may be a different solution for different application. That's why our research portfolio includes four themes. Not all four themes address the transistor. If you think of a integrated circuit, it's really a network of switches and the wires that connect us, which is three of the themes, address a different [00:06:00] type of switch while one theme address, how do you have more efficient wires or lower power consumption wires? Today's wars are copper wires, metal to wires, but we are doing research to have the communication between switches being done optically Speaker 3: and just for the record, what are the four themes? Speaker 1: The first theme is Nano Electronics. [00:06:30] The second theme is Nano mechanics. The third theme is nanophotonics and the fourth theme is Nano magnetics and you can see the first, second and fourth addresses. How do you get a different type of switch? While the third theme addresses the interconnection, namely the use of light for the interconnection amongst the switches [00:07:00] that we also call optical interconnect. Speaker 3: How interdisciplinary is the center? Do you have a sense of that in terms of the investigators and the researchers? Speaker 1: The center is highly into disciplinary disciplines involved. Our electrical engineering, chemistry material science and Physics Speaker 4: [inaudible]Speaker 3: [00:07:30] you are listening to spectrum of public affairs show on k a l x Berkeley public. Our guest is Josephine n. She is the executive director of the three s center. In the next segment she details the e three s community college outreach group. [inaudible]. An [00:08:00] interesting part of the e three s center is the program you've developed with community colleges. Do you want to explain how that program began and what its goals are? Speaker 1: A science and technology center is expected to educate besides do research and the education is not only have graduate students, so in I'll propose which NSF we decided to focus [00:08:30] on community college students. The reason we decided to do that is because in California we have the largest community college system in the country and many women and underrepresented minority start their post high school education. In community colleges. Our needs to increase its output of workers in this fuse [00:09:00] state utilizes science and technology disciplines and in order to do that we have to be able to encourage and groom participants from populations that are typically underrepresented in the technical world and this really based on that consideration that we say less focus on encouraging students, helping students from community colleges [00:09:30] develop a career in science and engineering. Speaker 3: What can you tell me about how the program is working and how people participate in it? From the community college side, Speaker 1: we have a program on campus called the transfer to excellence and this program while started by the East Rehab Center has now expanded to include other centers. This has been made possible because in addition to [00:10:00] the east area centers grind, the National Science Foundation also gave us an additional three years grant to expand the community college program and that has allowed the program to place students not only in the [inaudible] center but also to other centers on campus. Namely coins, the deals with Nana mechanics and also [inaudible] that deals with [00:10:30] synthetic bio fuse. The students from community college come on campus in the summer for nine weeks to do research, the first weakest bootcamp with the learn some of the basics to prepare them to go into the labs and then for the other eight weeks they work in the lab on individual projects and at the end, in the last week of the internship, they have to [00:11:00] present their work both in terms of giving talks and also in the form of posters in a poster session and that typically takes place at the beginning of August. And how large is that program? Last summer we hosted approximately 15 students. Speaker 3: Does that sort of what your target is for each summer? Speaker 1: Yes. Between 12 to 15 is off target [inaudible]. Speaker 3: And how do people [00:11:30] in community colleges get involved in it? How do they get selected or how do they apply? Speaker 1: In the fall we go through what we consider our recruitment face. We Post the information about the program on the website of our center. The staff of the center also goes out on campus to recruit. We host workshops to share information about a program and also to provide pointers to potential [00:12:00] applicants, how best to prepare the application. We also have webinars with, again, the purpose of encouraging and guiding potential applicants and how to apply and we also work with various community college or Nay stations to promote the program. For example, we ran a workshop in a Mesa conference. Is it statewide? [00:12:30] Yes. We're very proud to say that we have brought students from Mount Shasta down to south of San Diego from the bay area to the central valley Speaker 3: and I suppose the hope is that the students will then go to four year colleges get degrees. Are you tracking at all their progress in that effort? Speaker 1: Yes. Clearly the number one goal of this program [00:13:00] is to use research to deepen the interests of these students in science and engineering and you can ensure that they will get a good career in science engineering. Minimally a four year degree is necessary, so helping the students to transfer to a four year institution is number one goal. In addition, we want to excite them enough that they would even set this sites to go to graduate [00:13:30] school. The program provides one on one advising on the transfer process, particularly to UC Berkeley but also to four year institution in general and this advising is done by tap advices, which is the transfer alliance projects. There's part of UC Berkeley's campus, 87% of our 2012 class has transferred [00:14:00] to to what you see last fall. Most of them came to UC Berkeley, but others went to other ucs as well and I believe one of them actually transferred to Columbia Speaker 3: and for students that are in community colleges it might be listening. The best way to find out about it is to go on your website. Speaker 1: Yes. That's the best way to find out about the program and is also through our website which is www.ethrees-center.org [00:14:30] this website not only provides information but it just through this website you do your online application, Speaker 3: the community college students that are coming, what are their science requirements? Speaker 1: The program takes students the summer before they apply to transfer to a four year institution. By then we expect the students [00:15:00] to have completed two calculus courses and three signs or engineering courses including one laboratory course. Speaker 2: Okay. Speaker 5: From is a science and technology show on KALX Berkeley. We are talking with Josephine. You went [00:15:30] in the next segment she talks about the hope of research migrating from the lab to Congress. Speaker 2: [inaudible]Speaker 3: the center's focus now is on research. Is there at some point if you're successful with your research, a capability to implement and build something that would be a prototype of sorts. Speaker 1: [00:16:00] We are very much in the science face of our center. As a matter of fact, we are very much encouraged by our funder to really focus on understanding the science as opposed to just using empirical methods to achieve device demonstration. Part of the center's strategic plan costs for at the end of our sentence life, which we expect to be 10 years. We will be [00:16:30] able to have one technology, namely our science will be mature enough that we have a technology that can be commercialized. On the other hand, we are expected along the way to be able to really understand how realistic our approaches so we will be expected to have certain types of prototype demonstration in the second five years [00:17:00] of our center. Also each theme we expect that I'll research may have some near term applications and actually as a example in theme three which is the Nanophotonics we expect that I'll work in photo detectors can have near term applications. Speaker 3: So in a sense kind of spinning off some of the early successes within the center or do you have to move it out of the center to other [00:17:30] players? Speaker 1: They have different ways of transferring the knowledge that we gained through our research. The center has industry partners. This industry partners are leaders in the electronics industry. They have recognized the neat off the center and we should clearly we see them s one of the avenues to transfer technology that Nia term along the term [00:18:00] technologies that may come after center, but as you know, they also many other venues including potentially some of our students taking technologies and creating companies [inaudible] Speaker 3: so the industry partners also are able to feed back to you, give you some reflection on your research. Speaker 1: The feedback will enable the center to conduct this research to be practical and useful Speaker 3: [00:18:30] with the publications. Are there any restrictions on who you can publish with? Are you seeking out open source journals? Speaker 1: The Sentis research results are publish through peer review journals. Many of these journals, one could argue is not open source because you need a subscription to get to them. However, the journals allow the authors to post the papers on [00:19:00] their own website. I'll send to identifies on our website, our list of publications and through the authors own website, the public can gain access to those papers. Speaker 3: Are there other centers or other research groups that are doing very similar work that you pay close attention to? Speaker 1: Yes, there is a center in Notre Dame that [00:19:30] is partially funded by DARPA and another government agency. That center involves not only Notre Dame, Bifido is headquartered there, but it also has members from many of the academic institutions. The name of the center is leased. The center has similar goals as us. We are not the only people that recognized the problem the semiconductor industry is facing, [00:20:00] so there are many efforts and many researchers around the world working on different approaches to solving the problem. We are one of several centers. We believe we differentiate ourselves in part because we have really put a strong emphasis on establishing the science and understanding what has prevented an easy solution. Speaker 3: In your personal [00:20:30] story, you've spent some time on both sides of the granting process being with the NSF. What does it like seeing both sides of the process?Speaker 1: I was the SPI, our program officer at the National Science Foundation before coming to UC Berkeley at the Star Center. A programs officer's job is to figure out what area to fund. And in conjunction with review panels, recommend [00:21:00] which particular proposals you fund. And then after the award, the program office is job is to advise, guide, oversee the delivery of results and ensure that the grantee is in compliance with the program requirements. But when you are grantee, your job is to deliver on what you promise. So a lot of the focus is on results delivery [00:21:30] while a programs office job is to facilitate guide help, but not directly involved with the results delivery [inaudible] which do you prefer? My background prior to going to national science foundation was in private industry. So I have a very strong operating background. So to a certain extent, one can argue that given the number of years I've spent [00:22:00] operating or delivering results, that comes to me more naturally. Speaker 6: Josephine n, thank you very much for coming on spectrum. Speaker 1: Thank you for having me. Speaker 2: [inaudible]Speaker 5: for more details [00:22:30] on the [inaudible] center and their educational program, which covers pre college undergraduate, graduate and postdoc opportunities. Go to the e three s website, which is e three s-center.org spectrum shows are archived on iTunes university and we have created a simple link to help you get there. The link is tiny url.com/kalx [00:23:00] spectrum Speaker 2: [inaudible].Speaker 5: We hope you can get out to a few of the science and technology events happening locally over the next two years. Two weeks. Speaker 6: Renee Rao and chase Jacabowski present the calendar this Monday, February 24th come check out the next edition of nerd night. East Bay featuring lectures such as explosions, [00:23:30] back drafts and sprinklers, how Hollywood gets fire science wrong by Joel Sipe. Then listen to Brian Dote from sweet Mary's coffee and he'll show us how a cherry becomes black gold in his lecture home coffee roasting on the with tools you probably already have and last Vincent tank way will teach us about hyper velocity launchers in his lecture. Hyper velocity launchers, how to launch a projectile at 10 meters per second. That's right. 10 meters per second. Once again, nerd night takes [00:24:00] place. February 24th at the new parkway cinema in Oakland. Doors Open at 7:00 PM on Monday, March 3rd Dr. Edward Stone of Caltech will be giving a talk about the voyager spacecraft missions into interstellar space launched in 1977 to explore Jupiter, Saturn, Uranus, and Neptune. The two voyager spacecrafts continue their journeys as they search for the Helio pause. Speaker 6: The heliopause is a boundary between the solar wind and the local interstellar medium. [00:24:30] Recently in August, 2012 voyager one seem to be finally entering into the heliopause. The spacecraft reported finding depleted low energy particles originating from inside the heliosphere as well as low energy cosmic rays from nearby regions of the Milky Way. These in subsequent observations of the heliopause are revealing new aspects of the complex interaction of our son with a local interstellar medium to hear a complete history and learn where the voyager is. Now. Join Dr. Stone on [00:25:00] March 3rd at 4:15 PM in [inaudible] room number one on my name, March 3rd at 7:30 PM hello fellow Dr Jacqueline. Ferritin will speak in the planetarium of the California Academy of Sciences. At the close of 2013 the Italian stars with planets orbiting them toppled more than 1000 the majority of these so-called exoplanets have not actually been seen, but rather inferred from their effect on their host stars through pain seeking technical methods and tremendous telescope [00:25:30] 10 handful of indirectly image and these giant planets have shown fascinating diversity in their sizes, temperatures, weather, and relationships to their parents. Speaker 6: Sends over the past several years, an entirely new and mysterious breed of planets has emerged. As genres have discovered a collection of orphans. Planets that are moving through the galaxy, seemingly unattached to a star in this talk fairly will highlight how we discovered these seemingly impossible objects and review how these strange, exotic planets may be key [00:26:00] players in our understanding of planet formation and evolution. Her talk will be held seven 30 on Monday night, March 3rd go to cal academy.org to reserve tickets. A feature of spectrum is to present new stories we find interesting. Tracy Jakubowski and Renee Rao present our news, the deal. Cal reports a new project from UC Berkeley. Researchers may soon allow the power of ocean waves to join solar and wind power as a commercialized source of energy. [00:26:30] The project is led by Marcus Lehman, a visiting graduate student in the Mechanical Engineering Department and supervised by razor alum and assistant professor of mechanical engineering and principal investigator of the research. Speaker 6: The project focuses on building a prototype of a sea floor carpet that can generate electricity by mimicking the properties of the muddy sea floor. Therefore, the group is designing a c floor carpet waive dampening system that will harness the energy of waves passing over it. Theoretically, the [00:27:00] energy generated by 10 meters of sea floor carpet will be roughly equivalent to the energy conducted by a stadium sized soccer field completely covered by solar panels. As more and more people move to live near coastlines, the researchers expect wave power to be a top contender as the next big renewable resource, especially because waves have very high energy density. The cost of building devices to harness wave power is high. LM said, the ocean is a difficult place to work and our devices have to be sturdy enough to combat [00:27:30] the oceans, corrosive and harsh environments, but there's an increasing need for clean and as socially acceptable forms of generating power. Speaker 6: We're working hard with scientists and engineers to make this happen and it's only a matter of time. A recent study published in the Open Access Journal microbiome examine the GI tract of premature infants in the neonatal intensive care unit or NICU. The lead author of the study, Brandon Brooks, a graduate student in the plant and microbial biology department at UC Berkeley, collaborated [00:28:00] with researchers university of Pittsburgh to swab the most touched surfaces at the NICU, as well as collect samples from two premature babies. In a small pilot study, they discovered the microbial environment of the baby's GI tracks was strikingly similar to that of the NICU, which was particularly interesting given that the premature babies were treated with antibiotics and should have had a very limited diversity of micro organisms within their GI tract. Well, most of the micro organisms were opportunistic. A few contain genes that conferred resistance [00:28:30] to antibiotics and disinfectant that was used within the NICU. The study provided an important insight into how the pathogenic, as well as nonpathogenic organisms are able to move from even the most sterile of environments to our bodies. Speaker 4: [inaudible] [inaudible] Speaker 7: the music heard during the show was written and produced by [00:29:00] Alex Simon Speaker 8: [inaudible].Speaker 7: Thank you for listening to spectrum. If you have comments about the show, please send them to us via email or email address, spectrum dev, QA, and lex@yahoo.com genus in two weeks time. [inaudible]. Hosted on Acast. See acast.com/privacy for more information.